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Wyszukujesz frazę ""Pertussis Toxin"" wg kryterium: Temat


Tytuł :
Multiple weak interactions between BvgA~P and ptx promoter DNA strongly activate transcription of pertussis toxin genes in Bordetella pertussis.
Autorzy :
Chen Q; Division of Bacterial, Parasitic, and Allergenic Products, Center For Biologics Evaluation and Research, FDA, Silver Spring, Maryland, United States of America.
Boucher PE; Division of Bacterial, Parasitic, and Allergenic Products, Center For Biologics Evaluation and Research, FDA, Silver Spring, Maryland, United States of America.
Stibitz S; Division of Bacterial, Parasitic, and Allergenic Products, Center For Biologics Evaluation and Research, FDA, Silver Spring, Maryland, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 May 13; Vol. 16 (5), pp. e1008500. Date of Electronic Publication: 2020 May 13 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
Bordetella pertussis*/genetics
Bordetella pertussis*/metabolism
DNA, Bacterial*/genetics
DNA, Bacterial*/metabolism
Pertussis Toxin*/biosynthesis
Pertussis Toxin*/genetics
Promoter Regions, Genetic*
Transcription Factors*/genetics
Transcription Factors*/metabolism
Transcription, Genetic*
Adhesins, Bacterial/biosynthesis ; Adhesins, Bacterial/genetics ; Gene Expression Regulation, Bacterial/physiology ; Virulence Factors, Bordetella/biosynthesis ; Virulence Factors, Bordetella/genetics
Czasopismo naukowe
Tytuł :
Engineering of an Iranian Bordetella pertussis strain producing inactive pertussis toxin.
Autorzy :
Nikbin VS; Pertussis Reference Laboratory, Bacteriology Department, Pasteur Institute of Iran, Tehran, Iran.
Keramati M; Nano-Biotechnology Department, Pasteur Institute of Iran, Tehran, Iran.
Noofeli M; Razi Vaccines and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
Tayebzadeh F; Pertussis Reference Laboratory, Bacteriology Department, Pasteur Institute of Iran, Tehran, Iran.
Kahali B; Pertussis Reference Laboratory, Bacteriology Department, Pasteur Institute of Iran, Tehran, Iran.
Shahcheraghi F; Pertussis Reference Laboratory, Bacteriology Department, Pasteur Institute of Iran, Tehran, Iran.
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Źródło :
Journal of medical microbiology [J Med Microbiol] 2020 Jan; Vol. 69 (1), pp. 111-119.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Bacterial/*genetics
Bordetella pertussis/*genetics
Bordetella pertussis/*immunology
Mutant Proteins/*genetics
Pertussis Toxin/*genetics
Pertussis Vaccine/*genetics
Animals ; Antigens, Bacterial/metabolism ; Antigens, Bacterial/toxicity ; CHO Cells ; Cell Survival/drug effects ; Cricetulus ; Iran ; Mutagenesis, Site-Directed ; Mutant Proteins/metabolism ; Mutant Proteins/toxicity ; Pertussis Toxin/metabolism ; Pertussis Toxin/toxicity ; Pertussis Vaccine/adverse effects ; Protein Engineering ; Vaccines, Attenuated/adverse effects ; Vaccines, Attenuated/genetics
Czasopismo naukowe
Tytuł :
Collaborative study for the calibration of the replacement International Standard for pertussis toxin for use in histamine sensitisation and CHO cell clustering assays.
Autorzy :
Douglas-Bardsley A; Division of Bacteriology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, EN6 3QG, UK.
Asokanathan C; Division of Bacteriology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, EN6 3QG, UK.
Tierney S; Division of Bacteriology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, EN6 3QG, UK.
Hockley J; Biostatistics, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, EN6 3QG, UK.
Markey K; Division of Bacteriology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, EN6 3QG, UK. Electronic address: .
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Źródło :
Biologicals : journal of the International Association of Biological Standardization [Biologicals] 2019 Nov; Vol. 62, pp. 85-92. Date of Electronic Publication: 2019 Sep 13.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Bordetella pertussis*
Pertussis Toxin*/analysis
Pertussis Toxin*/chemistry
Pertussis Toxin*/standards
Pertussis Vaccine*/analysis
Pertussis Vaccine*/chemistry
Pertussis Vaccine*/standards
Animals ; CHO Cells ; Calibration ; Cricetulus ; Freeze Drying ; Histamine
Czasopismo naukowe
Tytuł :
Assays for Determining Pertussis Toxin Activity in Acellular Pertussis Vaccines.
Autorzy :
Markey K; Division of Bacteriology, National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK. .
Asokanathan C; Division of Bacteriology, National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK.
Feavers I; Division of Bacteriology, National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK.
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Źródło :
Toxins [Toxins (Basel)] 2019 Jul 17; Vol. 11 (7). Date of Electronic Publication: 2019 Jul 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Pertussis Toxin/*analysis
Pertussis Vaccine/*analysis
Animals ; Biological Assay ; Humans ; Pertussis Toxin/toxicity
Czasopismo naukowe
Tytuł :
T cell and chemokine receptors differentially control CD8 T cell motility behavior in the infected airways immediately before and after virus clearance in a primary infection.
Autorzy :
Emo K; David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, Rochester, NY, United States of America.
Reilly EC; David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, Rochester, NY, United States of America.
Sportiello M; David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, Rochester, NY, United States of America.
Yang H; Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, United States of America.
Topham DJ; David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, Rochester, NY, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Aug 20; Vol. 15 (8), pp. e0227157. Date of Electronic Publication: 2020 Aug 20 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
CD8-Positive T-Lymphocytes/*immunology
Cell Movement/*physiology
Influenza A virus/*immunology
Animals ; CD8-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/physiology ; Cell Movement/drug effects ; Chemokines/immunology ; Influenza A virus/pathogenicity ; Male ; Mice ; Mice, Inbred C57BL ; Orthomyxoviridae ; Orthomyxoviridae Infections/immunology ; Pertussis Toxin/metabolism ; Pertussis Toxin/pharmacology ; Receptors, Chemokine ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Tytuł :
Boosting Teenagers With Acellular Pertussis Vaccines Containing Recombinant or Chemically Inactivated Pertussis Toxin: A Randomized Clinical Trial.
Autorzy :
Blanchard Rohner G; Department of Paediatrics, Children's Hospital of Geneva, University Hospitals of Geneva.; Center for Vaccinology and Neonatal Immunology, Department of Pediatrics and Pathology-Immunology, Medical Faculty and University Hospitals of Geneva, Switzerland.
Chatzis O; Department of Paediatrics, Children's Hospital of Geneva, University Hospitals of Geneva.; Center for Vaccinology and Neonatal Immunology, Department of Pediatrics and Pathology-Immunology, Medical Faculty and University Hospitals of Geneva, Switzerland.
Chinwangso P; BioNet-Asia Co, Ltd, Bangkok, Thailand.
Rohr M; Department of Paediatrics, Children's Hospital of Geneva, University Hospitals of Geneva.; Center for Vaccinology and Neonatal Immunology, Department of Pediatrics and Pathology-Immunology, Medical Faculty and University Hospitals of Geneva, Switzerland.
Grillet S; Center for Vaccinology and Neonatal Immunology, Department of Pediatrics and Pathology-Immunology, Medical Faculty and University Hospitals of Geneva, Switzerland.
Salomon C; Department of Paediatrics, Children's Hospital of Geneva, University Hospitals of Geneva.
Lemaître B; Laboratory of Vaccinology, University Hospitals of Geneva, Switzerland.
Boonrak P; Center of Excellence for Biomedical and Public Health Informatics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Lawpoolsri S; Center of Excellence for Biomedical and Public Health Informatics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Clutterbuck E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford.; National Institute for Health Research Oxford Biomedical Research Centre, United Kingdom.
Poredi IK; BioNet-Asia Co, Ltd, Bangkok, Thailand.
Wijagkanalan W; BioNet-Asia Co, Ltd, Bangkok, Thailand.
Spiegel J; BioNet-Asia Co, Ltd, Bangkok, Thailand.
Pham HT; BioNet-Asia Co, Ltd, Bangkok, Thailand.
Viviani S; BioNet-Asia Co, Ltd, Bangkok, Thailand.
Siegrist CA; Department of Paediatrics, Children's Hospital of Geneva, University Hospitals of Geneva.; Center for Vaccinology and Neonatal Immunology, Department of Pediatrics and Pathology-Immunology, Medical Faculty and University Hospitals of Geneva, Switzerland.
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Źródło :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2019 Mar 19; Vol. 68 (7), pp. 1213-1222.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Neutralizing/*blood
Immunization, Secondary/*methods
Pertussis Toxin/*immunology
Pertussis Vaccine/*immunology
Whooping Cough/*prevention & control
Adhesins, Bacterial/genetics ; Adhesins, Bacterial/immunology ; Adolescent ; Antibodies, Bacterial/blood ; Antitoxins/blood ; B-Lymphocyte Subsets/immunology ; Child ; Female ; Humans ; Immunologic Memory ; Male ; Pertussis Toxin/genetics ; Pertussis Vaccine/administration & dosage ; Switzerland ; Vaccines, Acellular/administration & dosage ; Vaccines, Acellular/immunology ; Vaccines, Synthetic/administration & dosage ; Vaccines, Synthetic/immunology ; Virulence Factors, Bordetella/genetics ; Virulence Factors, Bordetella/immunology
Czasopismo naukowe
Tytuł :
The global prevalence ptxP3 lineage of Bordetella pertussis was rare in young children with the co-purified aPV vaccination: a 5 years retrospective study.
Autorzy :
Wang Z; Xi'an Children's Hospital, 69 Xijunyuan Road, Xi'an, 710002, Shaanxi Province, China. .
Luan Y; Xi'an Center for Disease Control and Prevention, 599 Xiying Road, Xi'an, 710054, China.
Du Q; Xi'an Center for Disease Control and Prevention, 599 Xiying Road, Xi'an, 710054, China.
Shu C; Xi'an Children's Hospital, 69 Xijunyuan Road, Xi'an, 710002, Shaanxi Province, China.
Peng X; Xi'an Children's Hospital, 69 Xijunyuan Road, Xi'an, 710002, Shaanxi Province, China.
Wei H; Xi'an Children's Hospital, 69 Xijunyuan Road, Xi'an, 710002, Shaanxi Province, China.
Hou T; Xi'an Center for Disease Control and Prevention, 599 Xiying Road, Xi'an, 710054, China.
Liu Y; Xi'an Center for Disease Control and Prevention, 599 Xiying Road, Xi'an, 710054, China.
Liu X; Xi'an Children's Hospital, 69 Xijunyuan Road, Xi'an, 710002, Shaanxi Province, China. .
Li Y; Xi'an Children's Hospital, 69 Xijunyuan Road, Xi'an, 710002, Shaanxi Province, China. .
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2020 Aug 19; Vol. 20 (1), pp. 615. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Bordetella pertussis/*drug effects
Bordetella pertussis/*genetics
Pertussis Toxin/*genetics
Pertussis Vaccine/*therapeutic use
Whooping Cough/*epidemiology
Alleles ; Anti-Bacterial Agents/pharmacology ; Bordetella pertussis/isolation & purification ; Child, Preschool ; China/epidemiology ; Drug Resistance, Bacterial/drug effects ; Drug Resistance, Bacterial/genetics ; Erythromycin/pharmacology ; Genotype ; Humans ; Microbial Sensitivity Tests ; Nasopharynx/microbiology ; Pertussis Vaccine/immunology ; Prevalence ; RNA, Ribosomal, 23S/genetics ; Retrospective Studies ; Vaccination ; Whooping Cough/microbiology ; Whooping Cough/prevention & control
Czasopismo naukowe
Tytuł :
Genetically detoxified pertussis toxin induces superior antigen specific CD4 T cell responses compared to chemically detoxified pertussis toxin.
Autorzy :
Surendran N; a Center for Infectious Diseases and Immunology , Rochester General Hospital Research Institute , Rochester , NY , USA.
Pichichero M; a Center for Infectious Diseases and Immunology , Rochester General Hospital Research Institute , Rochester , NY , USA.
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Źródło :
Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2019; Vol. 15 (5), pp. 1167-1170. Date of Electronic Publication: 2019 Mar 19.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Lymphocyte Activation*
CD4-Positive T-Lymphocytes/*immunology
Pertussis Toxin/*immunology
Antigens, CD/genetics ; Antigens, Differentiation, T-Lymphocyte/genetics ; Cells, Cultured ; Fetal Blood/cytology ; Humans ; Inactivation, Metabolic ; Infant, Newborn ; Interleukin-17/immunology ; Lectins, C-Type/genetics ; Leukocytes, Mononuclear/immunology ; Pertussis Toxin/chemistry ; Pertussis Toxin/genetics ; Pertussis Vaccine/immunology
Czasopismo naukowe
Tytuł :
Neuroinflammation and B-Cell Phenotypes in Cervical and Lumbosacral Regions of the Spinal Cord in Experimental Autoimmune Encephalomyelitis in the Absence of Pertussis Toxin.
Autorzy :
Kummari E; Center for Environmental Health Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA.; Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA.
Nichols JM; Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA.
Yang EJ; Center for Environmental Health Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA.; Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA.
Kaplan BLF; Center for Environmental Health Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA, .; Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA, .
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Źródło :
Neuroimmunomodulation [Neuroimmunomodulation] 2019; Vol. 26 (4), pp. 198-207. Date of Electronic Publication: 2019 Aug 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
B-Lymphocytes/*immunology
Encephalomyelitis, Autoimmune, Experimental/*chemically induced
Inflammation/*immunology
Pertussis Toxin/*pharmacology
Spinal Cord/*immunology
Adjuvants, Immunologic/pharmacology ; Animals ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Female ; Lumbosacral Region ; Mice, Inbred C57BL ; Myelin-Oligodendrocyte Glycoprotein/immunology ; Myelin-Oligodendrocyte Glycoprotein/pharmacology ; Peptide Fragments/immunology ; Peptide Fragments/pharmacology ; Pertussis Toxin/immunology ; Phenotype ; Spinal Cord/drug effects
Czasopismo naukowe
Tytuł :
A Novel Role for Somatostatin in the Survival of Mouse Pancreatic Beta Cells.
Autorzy :
Damsteegt EL; Health Science Research Group, Department of Life Sciences, University of Roehampton, London, UK.
Hassan Z; Department of Diabetes, School of Life Course Sciences, King's College London, London, UK.
Hewawasam NV; Health Science Research Group, Department of Life Sciences, University of Roehampton, London, UK.
Sarnsamak K; Health Science Research Group, Department of Life Sciences, University of Roehampton, London, UK.
Jones PM; Department of Diabetes, School of Life Course Sciences, King's College London, London, UK.
Hauge-Evans AC; Health Science Research Group, Department of Life Sciences, University of Roehampton, London, UK, .
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Źródło :
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology [Cell Physiol Biochem] 2019; Vol. 52 (3), pp. 486-502. Date of Electronic Publication: 2019 Mar 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Proliferation/*drug effects
Glucose/*antagonists & inhibitors
Insulin-Secreting Cells/*drug effects
Islets of Langerhans/*drug effects
Pertussis Toxin/*antagonists & inhibitors
Somatostatin/*pharmacology
Animals ; Apoptosis/drug effects ; Caspase 3/genetics ; Caspase 3/metabolism ; Caspase 7/genetics ; Caspase 7/metabolism ; Cell Line ; Chemokine CCL2/genetics ; Chemokine CCL2/metabolism ; Gene Expression Regulation ; Glucose/pharmacology ; HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/metabolism ; Insulin-Secreting Cells/cytology ; Insulin-Secreting Cells/metabolism ; Interleukin-1beta/antagonists & inhibitors ; Interleukin-1beta/pharmacology ; Islets of Langerhans/metabolism ; Male ; Mice ; Mice, Inbred ICR ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; Palmitic Acid/antagonists & inhibitors ; Palmitic Acid/pharmacology ; Pertussis Toxin/pharmacology ; Tissue Culture Techniques ; Transcription Factor CHOP/genetics ; Transcription Factor CHOP/metabolism ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Tumor Necrosis Factor-alpha/pharmacology
Czasopismo naukowe
Tytuł :
Humanised monoclonal antibodies neutralise pertussis toxin by receptor blockade and reduced retrograde trafficking.
Autorzy :
Acquaye-Seedah E; Department of Biochemistry, The University of Texas at Austin, Austin, Texas.; Department of Chemical Engineering, The University of Texas at Austin, Austin, Texas.
Huang Y; Department of Cell and Molecular Biology, The University of Texas at Austin, Austin, Texas.; Department of Chemical Engineering, The University of Texas at Austin, Austin, Texas.
Sutherland JN; Department of Chemical Engineering, The University of Texas at Austin, Austin, Texas.
DiVenere AM; Department of Chemical Engineering, The University of Texas at Austin, Austin, Texas.
Maynard JA; Department of Biochemistry, The University of Texas at Austin, Austin, Texas.; Department of Cell and Molecular Biology, The University of Texas at Austin, Austin, Texas.; Department of Chemical Engineering, The University of Texas at Austin, Austin, Texas.
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Źródło :
Cellular microbiology [Cell Microbiol] 2018 Dec; Vol. 20 (12), pp. e12948. Date of Electronic Publication: 2018 Sep 23.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Monoclonal, Humanized/*pharmacology
Bordetella pertussis/*drug effects
Pertussis Toxin/*metabolism
Animals ; Antibodies, Monoclonal, Humanized/metabolism ; Bordetella pertussis/immunology ; Bordetella pertussis/metabolism ; CHO Cells ; Cricetulus ; Endocytosis/drug effects ; Humans ; Pertussis Toxin/toxicity ; Protein Transport/drug effects ; Receptors, IgG/metabolism
Czasopismo naukowe
Tytuł :
Antibody persistence after vaccination of adolescents with monovalent and combined acellular pertussis vaccines containing genetically inactivated pertussis toxin: a phase 2/3 randomised, controlled, non-inferiority trial.
Autorzy :
Pitisuttithum P; Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Ratchathewi, Bangkok, Thailand.
Chokephaibulkit K; Paediatric Infectious Diseases Unit, Department of Paediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, Thailand.
Sirivichayakul C; Department of Tropical Paediatrics, Faculty of Tropical Medicine, Mahidol University, Ratchathewi, Bangkok, Thailand.
Sricharoenchai S; Paediatric Infectious Diseases Unit, Department of Paediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, Thailand.
Dhitavat J; Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Ratchathewi, Bangkok, Thailand.
Pitisuthitham A; Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Ratchathewi, Bangkok, Thailand.
Phongsamart W; Paediatric Infectious Diseases Unit, Department of Paediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, Thailand.
Boonnak K; Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Ratchathewi, Bangkok, Thailand.
Lapphra K; Paediatric Infectious Diseases Unit, Department of Paediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, Thailand.
Sabmee Y; Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Ratchathewi, Bangkok, Thailand.
Wittawatmongkol O; Paediatric Infectious Diseases Unit, Department of Paediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, Thailand.
Chauhan M; BioNet-Asia, Bangjak, Prakanong, Bangkok, Thailand.
Wijagkanalan W; BioNet-Asia, Bangjak, Prakanong, Bangkok, Thailand.
Hommalai G; BioNet-Asia, Bangjak, Prakanong, Bangkok, Thailand.
Fortuna L; BioNet-Asia, Bangjak, Prakanong, Bangkok, Thailand.
Chinwangso P; BioNet-Asia, Bangjak, Prakanong, Bangkok, Thailand.
Poredi IK; BioNet-Asia, Bangjak, Prakanong, Bangkok, Thailand.
van den Biggelaar AHJ; BioNet-Asia, Bangjak, Prakanong, Bangkok, Thailand. Electronic address: .
Pham HT; BioNet-Asia, Bangjak, Prakanong, Bangkok, Thailand.
Viviani S; BioNet-Asia, Bangjak, Prakanong, Bangkok, Thailand.
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Źródło :
The Lancet. Infectious diseases [Lancet Infect Dis] 2018 Nov; Vol. 18 (11), pp. 1260-1268. Date of Electronic Publication: 2018 Sep 25.
Typ publikacji :
Clinical Trial, Phase II; Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Bacterial/*blood
Antitoxins/*blood
Pertussis Toxin/*immunology
Pertussis Vaccine/*immunology
Adolescent ; Asia ; Drug-Related Side Effects and Adverse Reactions/epidemiology ; Drug-Related Side Effects and Adverse Reactions/pathology ; Female ; Humans ; Male ; Pertussis Toxin/genetics ; Pertussis Vaccine/administration & dosage ; Pertussis Vaccine/adverse effects ; Pertussis Vaccine/genetics ; Seroconversion ; Single-Blind Method ; Time Factors ; Vaccines, Acellular/administration & dosage ; Vaccines, Acellular/adverse effects ; Vaccines, Acellular/genetics ; Vaccines, Acellular/immunology ; Vaccines, Combined/administration & dosage ; Vaccines, Combined/adverse effects ; Vaccines, Combined/genetics ; Vaccines, Combined/immunology ; Vaccines, Synthetic/administration & dosage ; Vaccines, Synthetic/adverse effects ; Vaccines, Synthetic/genetics ; Vaccines, Synthetic/immunology
Czasopismo naukowe
Tytuł :
Mucosal and systemic immune responses elicited by recombinant Lactococcus lactis expressing a fusion protein composed of pertussis toxin and filamentous hemagglutinin from Bordetella pertussis.
Autorzy :
Torkashvand A; Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran.
Bahrami F; Department of Immunology, Pasteur Institute of Iran, 69 Pasteur Ave., Tehran, 13169-43551, Islamic Republic of Iran.
Adib M; Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran.
Ajdary S; Department of Immunology, Pasteur Institute of Iran, 69 Pasteur Ave., Tehran, 13169-43551, Islamic Republic of Iran. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2018 Jul; Vol. 120, pp. 155-160. Date of Electronic Publication: 2018 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Immunization*
Adhesins, Bacterial/*immunology
Antigens, Bacterial/*immunology
Immunity, Mucosal/*immunology
Lactococcus lactis/*genetics
Lactococcus lactis/*metabolism
Pertussis Toxin/*immunology
Recombinant Fusion Proteins/*immunology
Virulence Factors, Bordetella/*immunology
Adhesins, Bacterial/genetics ; Administration, Intranasal ; Administration, Oral ; Animals ; Antibodies, Bacterial/blood ; Antibodies, Bacterial/immunology ; Antigens, Bacterial/genetics ; Cytokines/metabolism ; Female ; Gene Expression Regulation, Bacterial ; Genetic Vectors ; Immunoglobulin A ; Immunoglobulin G/blood ; Interferon-gamma/metabolism ; Lung/immunology ; Mice ; Mice, Inbred BALB C ; Pertussis Toxin/genetics ; Recombinant Fusion Proteins/genetics ; Spleen/immunology ; Th1 Cells/immunology ; Vaccines, Combined ; Virulence Factors, Bordetella/genetics ; Whooping Cough/prevention & control
Czasopismo naukowe
Tytuł :
Pertussis in infants, in their mothers and other contacts in Casablanca, Morocco.
Autorzy :
Katfy, Khalid (AUTHOR)
Diawara, Idrissa (AUTHOR)
Maaloum, Fakhredine (AUTHOR)
Aziz, Siham (AUTHOR)
Guiso, Nicole (AUTHOR)
Fellah, Hassan (AUTHOR)
Slaoui, Bouchra (AUTHOR)
Zerouali, Khalid (AUTHOR)
Belabbes, Houria (AUTHOR)
Elmdaghri, Naima (AUTHOR)
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Źródło :
BMC Infectious Diseases. 1/14/2020, Vol. 20 Issue 1, p1-9. 9p. 3 Diagrams, 3 Charts, 1 Graph.
Czasopismo naukowe
Tytuł :
Characterization of Individual Human Antibodies That Bind Pertussis Toxin Stimulated by Acellular Immunization.
Autorzy :
Acquaye-Seedah E; Department of Biochemistry, The University of Texas at Austin, Austin, Texas, USA.
Reczek EE; Excelimmune, Inc., Woburn, Massachusetts, USA.
Russell HH; Excelimmune, Inc., Woburn, Massachusetts, USA.
DiVenere AM; McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, Texas, USA.
Sandman SO; Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, Michigan, USA.
Collins JH; Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, Michigan, USA.
Stein CA; Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, Michigan, USA.
Whitehead TA; Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, Michigan, USA.; Department of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, Michigan, USA.; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan, USA.
Maynard JA; Department of Biochemistry, The University of Texas at Austin, Austin, Texas, USA .; McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, Texas, USA.
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Źródło :
Infection and immunity [Infect Immun] 2018 May 22; Vol. 86 (6). Date of Electronic Publication: 2018 May 22 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antibodies, Bacterial/*immunology
Pertussis Toxin/*immunology
Pertussis Vaccine/*immunology
Adult ; Amino Acid Sequence ; Antibodies, Bacterial/blood ; Epitopes/immunology ; Humans ; Models, Molecular ; Pertussis Toxin/chemistry ; Protein Binding ; Protein Conformation ; Protein Subunits ; Vaccines, Acellular/immunology
Czasopismo naukowe
Tytuł :
An ELISA method to estimate the mono ADP-ribosyltransferase activities: e.g in pertussis toxin and vaccines.
Autorzy :
Asokanathan C; Division of Bacteriology, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK. Electronic address: .
Tierney S; Division of Bacteriology, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Ball CR; TDI, National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Buckle G; Division of Bacteriology, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Day A; Division of Bacteriology, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Tanley S; Division of Bacteriology, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Bristow A; TDI, National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Markey K; Division of Bacteriology, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Xing D; Division of Bacteriology, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Yuen CT; TDI, National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
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Źródło :
Analytical biochemistry [Anal Biochem] 2018 Jan 01; Vol. 540-541, pp. 15-19. Date of Electronic Publication: 2017 Nov 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enzyme-Linked Immunosorbent Assay*
ADP Ribose Transferases/*analysis
ADP Ribose Transferases/*metabolism
Enzyme Assays/*methods
Pertussis Toxin/*metabolism
Vaccines, Conjugate/*metabolism
ADP Ribose Transferases/antagonists & inhibitors ; Chromatography, High Pressure Liquid ; Clostridium/enzymology ; Escherichia coli/enzymology ; Escherichia coli/metabolism ; Humans ; Peptides/chemistry ; Peptides/metabolism ; Pertussis Toxin/analysis ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Substrate Specificity ; Vaccines, Conjugate/analysis
Czasopismo naukowe
Tytuł :
Neutralization of pertussis toxin by a single antibody prevents clinical pertussis in neonatal baboons.
Autorzy :
Nguyen AW; Department of Chemical Engineering, University of Texas at Austin, Austin, TX 78712, USA.
DiVenere AM; Department of Chemical Engineering, University of Texas at Austin, Austin, TX 78712, USA.
Papin JF; Division of Comparative Medicine, Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Connelly S; Synthetic Biologics, 9605 Medical Center Dr., Suite 270, Rockville, MD 20850, USA.
Kaleko M; Synthetic Biologics, 9605 Medical Center Dr., Suite 270, Rockville, MD 20850, USA.
Maynard JA; Department of Chemical Engineering, University of Texas at Austin, Austin, TX 78712, USA.
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Źródło :
Science advances [Sci Adv] 2020 Feb 05; Vol. 6 (6), pp. eaay9258. Date of Electronic Publication: 2020 Feb 05 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Bacterial/*immunology
Antibodies, Neutralizing/*immunology
Bordetella pertussis/*immunology
Monkey Diseases/*prevention & control
Pertussis Toxin/*immunology
Whooping Cough/*veterinary
Animals ; Antibodies, Bacterial/administration & dosage ; Antibodies, Neutralizing/administration & dosage ; Leukocyte Count ; Mice ; Monkey Diseases/diagnosis ; Monkey Diseases/mortality ; Neutralization Tests ; Papio
Czasopismo naukowe
Tytuł :
Androgen dihydrotestosterone (DHT) promotes the bladder cancer nuclear AR-negative cell invasion via a newly identified membrane androgen receptor (mAR-SLC39A9)-mediated Gαi protein/MAPK/MMP9 intracellular signaling.
Autorzy :
Chen J; Departments of Urology, Xiangya Hospital, Central South University, 410008, Changsha, China.; George Whipple Lab for Cancer Research, Departments of Pathology, Urology, Radiation Oncology, and The Wilmot Cancer Center, University of Rochester Medical Institute, Rochester, NY, USA.
Chou F; George Whipple Lab for Cancer Research, Departments of Pathology, Urology, Radiation Oncology, and The Wilmot Cancer Center, University of Rochester Medical Institute, Rochester, NY, USA.
Yeh S; George Whipple Lab for Cancer Research, Departments of Pathology, Urology, Radiation Oncology, and The Wilmot Cancer Center, University of Rochester Medical Institute, Rochester, NY, USA.
Ou Z; Departments of Urology, Xiangya Hospital, Central South University, 410008, Changsha, China.; George Whipple Lab for Cancer Research, Departments of Pathology, Urology, Radiation Oncology, and The Wilmot Cancer Center, University of Rochester Medical Institute, Rochester, NY, USA.
Shyr C; Sex Hormone Research Center, Departments of Urology and Medical Technology, China Medical University/Hospital, 404, Taichung, Taiwan.
Huang C; Sex Hormone Research Center, Departments of Urology and Medical Technology, China Medical University/Hospital, 404, Taichung, Taiwan.
Xiang Z; George Whipple Lab for Cancer Research, Departments of Pathology, Urology, Radiation Oncology, and The Wilmot Cancer Center, University of Rochester Medical Institute, Rochester, NY, USA.
Sun Y; George Whipple Lab for Cancer Research, Departments of Pathology, Urology, Radiation Oncology, and The Wilmot Cancer Center, University of Rochester Medical Institute, Rochester, NY, USA.
Messing E; George Whipple Lab for Cancer Research, Departments of Pathology, Urology, Radiation Oncology, and The Wilmot Cancer Center, University of Rochester Medical Institute, Rochester, NY, USA.
Zu X; Departments of Urology, Xiangya Hospital, Central South University, 410008, Changsha, China. .
Chang C; George Whipple Lab for Cancer Research, Departments of Pathology, Urology, Radiation Oncology, and The Wilmot Cancer Center, University of Rochester Medical Institute, Rochester, NY, USA. .; Sex Hormone Research Center, Departments of Urology and Medical Technology, China Medical University/Hospital, 404, Taichung, Taiwan. .
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Źródło :
Oncogene [Oncogene] 2020 Jan; Vol. 39 (3), pp. 574-586. Date of Electronic Publication: 2019 Sep 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cation Transport Proteins/*metabolism
Cell Membrane/*metabolism
Dihydrotestosterone/*metabolism
Urinary Bladder/*pathology
Urinary Bladder Neoplasms/*pathology
Androgen Antagonists/pharmacology ; Animals ; Cation Transport Proteins/genetics ; Cell Line, Tumor ; Cell Movement ; Cystectomy ; Datasets as Topic ; Disease Progression ; Female ; GTP-Binding Protein alpha Subunits, Gi-Go/antagonists & inhibitors ; GTP-Binding Protein alpha Subunits, Gi-Go/genetics ; GTP-Binding Protein alpha Subunits, Gi-Go/metabolism ; Humans ; Indazoles/pharmacology ; MAP Kinase Signaling System/drug effects ; MAP Kinase Signaling System/genetics ; Male ; Matrix Metalloproteinase 9/metabolism ; Mice ; Middle Aged ; Neoplasm Invasiveness/pathology ; Pertussis Toxin/pharmacology ; Piperazines/pharmacology ; Prognosis ; RNA, Small Interfering/metabolism ; Urinary Bladder/cytology ; Urinary Bladder/surgery ; Urinary Bladder Neoplasms/mortality ; Urinary Bladder Neoplasms/surgery
Czasopismo naukowe
Tytuł :
Thyrotropin Causes Dose-dependent Biphasic Regulation of cAMP Production Mediated by G s and G i/o Proteins.
Autorzy :
Neumann S; Laboratory of Endocrinology and Receptor Biology (S.N., S.S.M., B.M.-S., E.E., D.J., C.C.K., M.C.G.) and Metabolic Disease Branch (J.K.-G.), National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Malik SS; Laboratory of Endocrinology and Receptor Biology (S.N., S.S.M., B.M.-S., E.E., D.J., C.C.K., M.C.G.) and Metabolic Disease Branch (J.K.-G.), National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Marcus-Samuels B; Laboratory of Endocrinology and Receptor Biology (S.N., S.S.M., B.M.-S., E.E., D.J., C.C.K., M.C.G.) and Metabolic Disease Branch (J.K.-G.), National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Eliseeva E; Laboratory of Endocrinology and Receptor Biology (S.N., S.S.M., B.M.-S., E.E., D.J., C.C.K., M.C.G.) and Metabolic Disease Branch (J.K.-G.), National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Jang D; Laboratory of Endocrinology and Receptor Biology (S.N., S.S.M., B.M.-S., E.E., D.J., C.C.K., M.C.G.) and Metabolic Disease Branch (J.K.-G.), National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Klubo-Gwiezdzinska J; Laboratory of Endocrinology and Receptor Biology (S.N., S.S.M., B.M.-S., E.E., D.J., C.C.K., M.C.G.) and Metabolic Disease Branch (J.K.-G.), National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Krieger CC; Laboratory of Endocrinology and Receptor Biology (S.N., S.S.M., B.M.-S., E.E., D.J., C.C.K., M.C.G.) and Metabolic Disease Branch (J.K.-G.), National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Gershengorn MC; Laboratory of Endocrinology and Receptor Biology (S.N., S.S.M., B.M.-S., E.E., D.J., C.C.K., M.C.G.) and Metabolic Disease Branch (J.K.-G.), National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2020 Jan; Vol. 97 (1), pp. 2-8. Date of Electronic Publication: 2019 Nov 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Cyclic AMP/*metabolism
GTP-Binding Protein alpha Subunits, Gi-Go/*metabolism
Receptors, Thyrotropin/*metabolism
Signal Transduction/*drug effects
Thyrotropin/*administration & dosage
Dose-Response Relationship, Drug ; Down-Regulation ; Dynamin I/genetics ; Dynamin I/metabolism ; GTP-Binding Protein alpha Subunits, Gi-Go/antagonists & inhibitors ; GTP-Binding Protein alpha Subunits, Gi-Go/genetics ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Pertussis Toxin/administration & dosage ; Receptors, Thyrotropin/genetics ; Signal Transduction/genetics ; beta-Arrestin 2/genetics ; beta-Arrestin 2/metabolism
Czasopismo naukowe

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