Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease.
Autorzy:
Ricke-Hoch M; Department of Cardiology and Angiology, Hannover Medical School, Hanover, Germany. Stelling E; Department of Cardiology and Angiology, Hannover Medical School, Hanover, Germany. Lasswitz L; Institute of Experimental Virology, TWINCORE, Center for Experimental and Clinical Infection Research Hannover, Hanover, Germany. Gunesch AP; Institute of Experimental Virology, TWINCORE, Center for Experimental and Clinical Infection Research Hannover, Hanover, Germany.; German Center for Infection Research, Hanover-Braunschweig Site, Braunschweig, Germany.; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hanover, Germany. Kasten M; Department of Cardiology and Angiology, Hannover Medical School, Hanover, Germany. Zapatero-Belinchón FJ; Institute of Experimental Virology, TWINCORE, Center for Experimental and Clinical Infection Research Hannover, Hanover, Germany.; Department of Clinical Microbiology, Virology & Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå, Sweden. Brogden G; Institute of Experimental Virology, TWINCORE, Center for Experimental and Clinical Infection Research Hannover, Hanover, Germany. Gerold G; Institute of Experimental Virology, TWINCORE, Center for Experimental and Clinical Infection Research Hannover, Hanover, Germany.; Department of Clinical Microbiology, Virology & Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå, Sweden.; Department of Biochemistry, University of Veterinary Medicine Hannover, Hanover Germany. Pietschmann T; Institute of Experimental Virology, TWINCORE, Center for Experimental and Clinical Infection Research Hannover, Hanover, Germany.; German Center for Infection Research, Hanover-Braunschweig Site, Braunschweig, Germany. Montiel V; Pole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique, and Cliniques Universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Brussels, Belgium. Balligand JL; Pole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique, and Cliniques Universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Brussels, Belgium. Facciotti F; Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan, Italy. Hirsch E; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy. Gausepohl T; Department of Cardiology and Angiology, Hannover Medical School, Hanover, Germany. Elbahesh H; Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine in Hannover (TiHo), Hannover, Germany. Rimmelzwaan GF; Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine in Hannover (TiHo), Hannover, Germany. Höfer A; Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), German Center for Lung Research, Hanover, Germany.; Institute for Pathology, Hannover Medical School, Hanover, Germany. Kühnel MP; Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), German Center for Lung Research, Hanover, Germany.; Institute for Pathology, Hannover Medical School, Hanover, Germany. Jonigk D; Biomedical Research in Endstage and Obstructive Lung Disease (BREATH), German Center for Lung Research, Hanover, Germany.; Institute for Pathology, Hannover Medical School, Hanover, Germany. Eigendorf J; Institute of Sports Medicine, Hannover Medical School, Hanover, Germany. Tegtbur U; Institute of Sports Medicine, Hannover Medical School, Hanover, Germany. Mink L; Institute of Sports Medicine, Hannover Medical School, Hanover, Germany. Scherr M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hanover, Germany. Illig T; Hannover Unified Biobank (HUB), Hannover Medical School, Hanover, Germany. Schambach A; Institute of Experimental Hematology, Hannover Medical School, Hanover, Germany.; Division of Hematology and Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States of America. Pfeffer TJ; Department of Cardiology and Angiology, Hannover Medical School, Hanover, Germany. Hilfiker A; Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hanover, Germany. Haverich A; Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hanover, Germany. Hilfiker-Kleiner D; Department of Cardiology and Angiology, Hannover Medical School, Hanover, Germany.; Department of Cardiovascular Complications of Oncologic Therapies, Medical Faculty of the Philipps University Marburg, Marburg, Germany.
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Źródło:
PloS one [PLoS One] 2021 Aug 04; Vol. 16 (8), pp. e0255335. Date of Electronic Publication: 2021 Aug 04 (Print Publication: 2021).
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