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Tytuł:
Case Report: Performing a Medication Safety Review Assisted by Pharmacogenomics to Explain a Prescribing Cascade Resulting in a Patient Fall.
Autorzy:
Russell J; Tabula Rasa HealthCare, Office of Translational Research and Residency Programs, Moorestown, NJ 08057, USA.
Arwood MJ; Tabula Rasa HealthCare, Precision Pharmacotherapy Research and Development Institute, Orlando, FL 32827, USA.
Toro-Pagán NMD; Tabula Rasa HealthCare, Office of Translational Research and Residency Programs, Moorestown, NJ 08057, USA.
Amin NS; Tabula Rasa HealthCare, Office of Translational Research and Residency Programs, Moorestown, NJ 08057, USA.
Cambridge MD; Franciscan Senior Health and Wellness, Program of All-Inclusive Care for the Elderly (PACE), Indianapolis, IN 46259, USA.
Turgeon J; Tabula Rasa HealthCare, Precision Pharmacotherapy Research and Development Institute, Orlando, FL 32827, USA.; Faculty of Pharmacy, Université de Montréal, Montréal, QC H3C 3J7, Canada.
Michaud V; Tabula Rasa HealthCare, Precision Pharmacotherapy Research and Development Institute, Orlando, FL 32827, USA.; Faculty of Pharmacy, Université de Montréal, Montréal, QC H3C 3J7, Canada.; Faculty of Pharmacy, University of Montreal Hospital Research Center (CRCHUM), Montréal, QC H2X 0A9, Canada.
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Źródło:
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2023 Jan 06; Vol. 59 (1). Date of Electronic Publication: 2023 Jan 06.
Typ publikacji:
Case Reports
MeSH Terms:
Pharmacogenetics*/methods
Depressive Disorder, Major*/drug therapy
Depressive Disorder, Major*/genetics
Humans ; Hydrocodone/therapeutic use ; Antidepressive Agents/adverse effects ; Fluoxetine/therapeutic use
Raport
Szczegóły
Tytuł:
Patient-derived cell-based pharmacogenomic assessment to unveil underlying resistance mechanisms and novel therapeutics for advanced lung cancer.
Autorzy:
Yu N; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.
Hwang M; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.
Lee Y; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.
Song BR; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.
Kang EH; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.
Sim H; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.
Ahn BC; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.
Hwang KH; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.
Kim J; Department of Precision Medicine, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju, 28159, Republic of Korea.
Hong S; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea.
Kim S; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea. .
Park C; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea. .
Han JY; Research Institute, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Republic of Korea. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Jan 30; Vol. 42 (1), pp. 37. Date of Electronic Publication: 2023 Jan 30.
Typ publikacji:
Journal Article
MeSH Terms:
Pharmacogenetics*
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Humans ; Phosphatidylinositol 3-Kinases/genetics ; ErbB Receptors/metabolism ; Drug Resistance, Neoplasm/genetics ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Phosphoinositide-3 Kinase Inhibitors/pharmacology ; Cell Line, Tumor ; Mutation ; Epithelial-Mesenchymal Transition/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Publication bias in pharmacogenetics of adverse reaction to antiseizure drugs: An umbrella review and a meta-epidemiological study.
Autorzy:
Bally S; Laboratoire de Biométrie et Biologie Evolutive UMR5558, Université Lyon 1, CNRS, Villeurbanne, France.
Cottin J; Service Hospitalo-Universitaire de Pharmacotoxicologie, Pôle de Santé Publique, Hospices Civils de Lyon, Lyon, France.
Gagnieu MC; Laboratoire de Pharmacologie, Groupement Hospitalier Sud, Hospices Civils De Lyon, Lyon, France.
Lega JC; Laboratoire de Biométrie et Biologie Evolutive UMR5558, Université Lyon 1, CNRS, Villeurbanne, France.; Service de Médecine Interne et Vasculaire, Hôpital Lyon Sud, Hospices Civils de Lyon, Lyon, France.
Verstuyft C; CESP, MOODS Team, INSERM, Faculté de Médecine, Université Paris-Saclay, Le Kremlin Bicêtre, France.; Service de Génétique Moléculaire, Pharmacogénétique et Hormonologie de Bicêtre, Hôpitaux Universitaires Paris-Sud, Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Le Kremlin Bicêtre, France.
Rheims S; Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon 1 University, Lyon, France.
Lesca G; Service de Génétique, Groupement Hospitalier Est, Hospices Civils De Lyon, Université Lyon 1, Lyon, France.
Cucherat M; Laboratoire de Biométrie et Biologie Evolutive UMR5558, Université Lyon 1, CNRS, Villeurbanne, France.; Service Hospitalo-Universitaire de Pharmacotoxicologie, Pôle de Santé Publique, Hospices Civils de Lyon, Lyon, France.
Grenet G; Service Hospitalo-Universitaire de Pharmacotoxicologie, Pôle de Santé Publique, Hospices Civils de Lyon, Lyon, France.
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Źródło:
PloS one [PLoS One] 2022 Dec 30; Vol. 17 (12), pp. e0278839. Date of Electronic Publication: 2022 Dec 30 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Pharmacogenetics*
Stevens-Johnson Syndrome*
Humans ; Publication Bias ; Systematic Reviews as Topic ; HLA-B Antigens ; Epidemiologic Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Considerations into pharmacogenomics of COVID-19 pharmacotherapy: Hope, hype and reality.
Autorzy:
Al-Taie A; Clinical Pharmacy Department, Faculty of Pharmacy, Istinye University, Istanbul, Turkey. Electronic address: .
Büyük AŞ; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Istinye University, Istanbul, Turkey.
Sardas S; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Istinye University, Istanbul, Turkey.
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Źródło:
Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2022 Dec; Vol. 77, pp. 102172. Date of Electronic Publication: 2022 Oct 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pharmacogenetics*
COVID-19 Drug Treatment*
Humans ; Precision Medicine ; Pandemics
Czasopismo naukowe
Szczegóły
Tytuł:
Integrating pharmacogenomics into precision pain management.
Autorzy:
Bates J; Department of Veterans Affairs, Durham, NC, USA.
Fudin J; Remitigate Therapeutics, Delmar, NY, USA.
Patel JN; Department of Cancer Pharmacology and Pharmacogenomics, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA. .
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Źródło:
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [Support Care Cancer] 2022 Dec; Vol. 30 (12), pp. 10453-10459. Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pharmacogenetics*/methods
Pain Management*
Humans ; Pain/drug therapy
Czasopismo naukowe
Szczegóły
Tytuł:
A paradigm shift in pharmacogenomics: From candidate polymorphisms to comprehensive sequencing.
Autorzy:
Zhou Y; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Koutsilieri S; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Eliasson E; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Lauschke VM; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany.
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Źródło:
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2022 Dec; Vol. 131 (6), pp. 452-464. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pharmacogenetics*/methods
High-Throughput Nucleotide Sequencing*/methods
Humans ; Polymorphism, Genetic ; Sequence Analysis, DNA/methods
Czasopismo naukowe
Szczegóły
Tytuł:
Long-read HiFi sequencing of NUDT15: Phased full-gene haplotyping and pharmacogenomic allele discovery.
Autorzy:
Scott ER; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Yang Y; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Botton MR; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Sema4, Stamford, Connecticut, USA.
Seki Y; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Hoshitsuki K; School of Pharmacy, University of Pittsburgh, Pennsylvania, Pittsburgh, USA.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Harting J; Pacific Biosciences, Menlo Park, California, USA.
Baybayan P; Pacific Biosciences, Menlo Park, California, USA.
Cody N; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Sema4, Stamford, Connecticut, USA.
Nicoletti P; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Sema4, Stamford, Connecticut, USA.
Moriyama T; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Chakraborty S; Pacific Biosciences, Menlo Park, California, USA.
Yang JJ; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Edelmann L; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Sema4, Stamford, Connecticut, USA.
Schadt EE; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Sema4, Stamford, Connecticut, USA.
Korlach J; Pacific Biosciences, Menlo Park, California, USA.
Scott SA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Sema4, Stamford, Connecticut, USA.
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Źródło:
Human mutation [Hum Mutat] 2022 Nov; Vol. 43 (11), pp. 1557-1566. Date of Electronic Publication: 2022 Sep 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Pharmacogenetics*
Alleles ; Genotype ; Haplotypes ; Humans ; Sequence Analysis, DNA/methods
Czasopismo naukowe
Szczegóły
Tytuł:
Precision medicine from a citizen perspective: a survey of public attitudes towards pharmacogenomics in Flanders.
Autorzy:
Edris A; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
Callier E; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
Lahousse L; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2022 Sep 12; Vol. 15 (Suppl 3), pp. 193. Date of Electronic Publication: 2022 Sep 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pharmacogenetics*
Precision Medicine*
Adolescent ; Adult ; Attitude ; Cross-Sectional Studies ; Female ; Humans ; Male ; Public Opinion ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetic Variation among Pharmacogenes in the Sardinian Population.
Autorzy:
Idda ML; Institute for Genetic and Biomedical Research, National Research Council, 07100 Sassari, Italy.
Zoledziewska M; Institute for Genetic and Biomedical Research, National Research Council, 09042 Monserrato, Italy.
Urru SAM; Hospital Pharmacy Unit, Trento General Hospital, Autonomous Province of Trento, 38122 Trento, Italy.; Department of Chemistry and Pharmacy, School of Hospital Pharmacy, University of Sassari, 07100 Sassari, Italy.
McInnes G; Biomedical Informatics Training Program, Stanford University, Stanford, CA 94305, USA.
Bilotta A; Department of Biomedical Sciences, School of Medicine, University of Sassari, 07100 Sassari, Italy.
Nuvoli V; Department of Biomedical Sciences, School of Medicine, University of Sassari, 07100 Sassari, Italy.
Lodde V; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Orrù S; Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, 09126 Cagliari, Italy.
Schlessinger D; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Cucca F; Institute for Genetic and Biomedical Research, National Research Council, 09042 Monserrato, Italy.; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Floris M; Institute for Genetic and Biomedical Research, National Research Council, 07100 Sassari, Italy.; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 02; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 02.
Typ publikacji:
Journal Article
MeSH Terms:
Pharmacogenetics*
Precision Medicine*
Gene Frequency ; Genetic Variation ; Pharmacogenomic Testing ; Pharmacogenomic Variants
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Fetal pharmacogenomics: A promising addition to complex neonatal care.
Autorzy:
Raymond M; Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA, USA.
Critchlow E; Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
Rice SM; Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA, USA.
Wodoslawsky S; Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
Berger SI; Center for Genetic Medicine Research at Children's National, Washington, DC, USA.
Hegde M; PerkinElmer Genomics, Atlanta, GA, USA.
Empey PE; Department of Pharmacy and Therapeutics, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Al-Kouatly HB; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA, USA. Electronic address: .
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Źródło:
Molecular genetics and metabolism [Mol Genet Metab] 2022 Sep-Oct; Vol. 137 (1-2), pp. 140-145. Date of Electronic Publication: 2022 Aug 12.
Typ publikacji:
Clinical Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytochrome P-450 CYP2D6*/genetics
Pharmacogenetics*/methods
Humans ; Infant, Newborn ; Cytochrome P-450 CYP2C19/genetics ; Cytochrome P-450 CYP2C9 ; Fetus ; Liver-Specific Organic Anion Transporter 1 ; Prospective Studies
Czasopismo naukowe
Szczegóły
Tytuł:
Pharmacogenetics of siponimod: A systematic review.
Autorzy:
Díaz-Villamarín X; Pharmacology Department. University of Granada (UGR), Granada, Spain; Pfizer - University of Granada, Junta de Andalucía Centre for Genomics and Oncological Research (GENYO), Granada, Spain. Electronic address: .
Piñar-Morales R; Neurology Department, Hospital Universitario Clínico San Cecilio-Instituto de Investigación Biosanitaria de Granada (ibs.Granada), Granada, Spain.
Barrero-Hernández FJ; Neurology Department, Hospital Universitario Clínico San Cecilio-Instituto de Investigación Biosanitaria de Granada (ibs.Granada), Granada, Spain.
Antúnez-Rodríguez A; Pfizer - University of Granada, Junta de Andalucía Centre for Genomics and Oncological Research (GENYO), Granada, Spain.
Cabeza-Barrera J; Pharmacy Department, Hospital Universitario Clínico San Cecilio-Instituto de Investigación Biosanitaria de Granada (ibs.Granada), Granada, Spain.
Morón-Romero R; Pharmacy Department, Hospital Universitario Clínico San Cecilio-Instituto de Investigación Biosanitaria de Granada (ibs.Granada), Granada, Spain.
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Sep; Vol. 153, pp. 113536. Date of Electronic Publication: 2022 Aug 12.
Typ publikacji:
Journal Article; Review; Systematic Review
MeSH Terms:
Azetidines*
Pharmacogenetics*
Benzyl Compounds/adverse effects ; Cytochrome P-450 CYP2C9/genetics ; Cytochrome P-450 CYP2C9/metabolism ; Genotype
Czasopismo naukowe
Szczegóły
Tytuł:
Pharmacogenetics may explain part of the interindividual variability of dobutamine pharmacodynamics in neonates.
Autorzy:
Hallik M; Department of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Soeorg H; Department of Microbiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Kahre T; Department of Clinical Genetics, United Laboratories, Tartu University Hospital, Tartu, Estonia.; Department of Clinical Genetics, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Murumets Ü; Department of Clinical Genetics, United Laboratories, Tartu University Hospital, Tartu, Estonia.
Ilmoja ML; Department of Anaesthesiology and Intensive Care, Tallinn Children's Hospital, Tallinn, Estonia.
Kipper K; Institute of Chemistry, University of Tartu, Tartu, Estonia.; Chalfont Centre for Epilepsy, Buckinghamshire, UK.; Department of Clinical and Experimental Epilepsy, Faculty of Brain Sciences, University College London, UK.
Metsvaht T; Department of Paediatrics, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
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Źródło:
British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 Sep; Vol. 88 (9), pp. 4155-4162. Date of Electronic Publication: 2022 Apr 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dobutamine*/pharmacology
Pharmacogenetics*
Critical Illness ; Female ; Heart Rate/genetics ; Humans ; Infant, Newborn ; Polymorphism, Single Nucleotide ; Pregnancy
Czasopismo naukowe
Szczegóły
Tytuł:
Fetal pharmacogenetic screening to improve neonatal pharmacotherapy: From feasibility to personalized practice.
Autorzy:
Yalcin N; Department of Clinical Pharmacy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Allegaert K; Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Leuven, Belgium; Leuven Child and Youth Institute, KU Leuven, Leuven, Belgium; Department of Clinical Pharmacy, Erasmus MC, Rotterdam, the Netherlands. Electronic address: .
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Źródło:
Molecular genetics and metabolism [Mol Genet Metab] 2022 Sep-Oct; Vol. 137 (1-2), pp. 210-212. Date of Electronic Publication: 2022 Sep 17.
Typ publikacji:
Journal Article
MeSH Terms:
Pharmacogenomic Testing*
Pharmacogenetics*
Female ; Infant, Newborn ; Pregnancy ; Humans ; Feasibility Studies ; Precision Medicine ; Prenatal Diagnosis
Czasopismo naukowe
Szczegóły
Tytuł:
Genetic polymorphisms of pharmacogenomic VIP variants in the Lahu population from Yunnan Province.
Autorzy:
Dou X; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, China.
Yang S; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, China.
Zhang W; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, China.
Meng W; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, China.
Zhao W; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, China.
Hao J; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, China.
Hu X; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, China.
Guo L; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, China.
Jin T; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, China; School of Medicine, Xizang Minzu University, Xianyang, Shaanxi 712082, China. Electronic address: .
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Źródło:
Gene [Gene] 2022 Nov 30; Vol. 844, pp. 146825. Date of Electronic Publication: 2022 Aug 19.
Typ publikacji:
Journal Article
MeSH Terms:
Cytochrome P-450 CYP3A*/genetics
Pharmacogenetics*
China ; Cyclooxygenase 2/genetics ; Gene Frequency ; Genotype ; Humans ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Szczegóły
Tytuł:
Evaluating the frequency and the impact of pharmacogenetic alleles in an ancestrally diverse Biobank population.
Autorzy:
Verma SS; Department of Pathology & Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Keat K; Genomics & Computational Biology PhD Program, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Li B; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.
Hoffecker G; Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Risman M; Department of Genetics and Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Sangkuhl K; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.
Whirl-Carrillo M; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.
Dudek S; Department of Genetics and Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Verma A; Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Klein TE; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.; Department of Biomedical Data Science and Medicine (BMIR), Stanford University, Stanford, CA, USA.
Ritchie MD; Department of Genetics and Institute for Biomedical Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Tuteja S; Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. .
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Corporate Authors:
Regeneron Genetics Center
Źródło:
Journal of translational medicine [J Transl Med] 2022 Nov 28; Vol. 20 (1), pp. 550. Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Pharmacogenetics*
Biological Specimen Banks*
Humans ; Alleles ; Cytochrome P-450 CYP2C19 ; Clopidogrel ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pharmacogenomics in the era of personalised medicine.
Autorzy:
White C; Maitland Hospital, Maitland, NSW.; University of Newcastle, Newcastle, NSW.
Scott R; University of Newcastle, Newcastle, NSW.; Pathology North, Newcastle, NSW.
Paul CL; University of Newcastle, Newcastle, NSW.; Priority Research Centre for Health Behaviour, University of Newcastle, Newcastle, NSW.
Ackland SP; Lake Macquarie Private Hospital, Gateshead, NSW.; Hunter Cancer Research Alliance, Newcastle, NSW.
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Źródło:
The Medical journal of Australia [Med J Aust] 2022 Nov 21; Vol. 217 (10), pp. 510-513. Date of Electronic Publication: 2022 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Pharmacogenetics*
Precision Medicine*
Humans
Czasopismo naukowe
Szczegóły
Tytuł:
Pharmacogenomics in Psychiatry Practice: The Value and the Challenges.
Autorzy:
Alchakee A; College of Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates.; Sharjah Institute for Medical Research, Sharjah 27272, United Arab Emirates.
Ahmed M; Sharjah Institute for Medical Research, Sharjah 27272, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.
Eldohaji L; Sharjah Institute for Medical Research, Sharjah 27272, United Arab Emirates.
Alhaj H; College of Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates.; Sharjah Institute for Medical Research, Sharjah 27272, United Arab Emirates.
Saber-Ayad M; College of Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates.; Sharjah Institute for Medical Research, Sharjah 27272, United Arab Emirates.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 03; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pharmacogenetics*
Psychiatry*
Humans ; Cytochrome P-450 CYP2D6/genetics ; Cytochrome P-450 Enzyme System/genetics ; Cytochrome P-450 Enzyme System/metabolism ; Psychotropic Drugs/adverse effects ; Psychotropic Drugs/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Methadone pharmacogenetics in vitro and in vivo: Metabolism by CYP2B6 polymorphic variants and genetic variability in paediatric disposition.
Autorzy:
Wang PF; Department of Anesthesiology, Duke University, Durham, NC, USA.
Sharma A; Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA, USA.
Montana M; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.
Neiner A; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.
Juriga L; University of Missouri, Columbia, MO, USA.
Reddy KN; Department of Pediatric Anesthesiology, Arkansas Children's Hospital, Little Rock, AK, USA.
Tallchief D; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.
Blood J; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.
Kharasch ED; Department of Anesthesiology, Duke University, Durham, NC, USA.
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Źródło:
British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 Nov; Vol. 88 (11), pp. 4881-4893. Date of Electronic Publication: 2022 Jun 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Methadone*
Pharmacogenetics*
Cytochrome P-450 CYP2B6/genetics ; Cytochrome P-450 CYP2B6/metabolism ; Cytochrome P-450 Enzyme System/metabolism ; Cytochromes b
Czasopismo naukowe
Szczegóły
Tytuł:
PharmaKoVariome database for supporting genetic testing.
Autorzy:
Kim J; Personal Genomics Institute (PGI), Genome Research Foundation (GRF), Cheongju 28190, Republic of Korea.
Choi JP; Personal Genomics Institute (PGI), Genome Research Foundation (GRF), Cheongju 28190, Republic of Korea.
Kim MS; Personal Genomics Institute (PGI), Genome Research Foundation (GRF), Cheongju 28190, Republic of Korea.
Bhak J; Personal Genomics Institute (PGI), Genome Research Foundation (GRF), Cheongju 28190, Republic of Korea.; Korean Genomics Center (KOGIC), Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.; Department of Biomedical Engineering, School of Life Sciences, UNIST, Ulsan 44919, Republic of Korea.; Clinomics, Inc., Ulsan 44919, Republic of Korea.
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Źródło:
Database : the journal of biological databases and curation [Database (Oxford)] 2022 Oct 18; Vol. 2022.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytochrome P-450 CYP2D6*/genetics
Pharmacogenetics*
Humans ; Cytochrome P-450 CYP2B6/genetics ; Genotype ; Genetic Testing ; Pharmaceutical Preparations ; Nucleotides
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Role of Pharmacogenomics in Opioid Prescribing.
Autorzy:
Wong AK; Parkville Integrated Palliative Care Service, The Royal Melbourne Hospital, 300 Grattan St, Parkville, Victoria, 3050, Australia. .; Department of Medicine, University of Melbourne, Eastern Hill Campus, Victoria Parade, Fitzroy, Victoria, 3065, Australia. .; Peter MacCallum Cancer Centre, Melbourne, Victoria, 3000, Australia. .
Somogyi AA; Discipline of Pharmacology, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, 5005, Australia.
Rubio J; Florey Institute of Neuroscience & Mental Health, 30 Royal Parade, Parkville, Victoria, 3052, Australia.
Philip J; Parkville Integrated Palliative Care Service, The Royal Melbourne Hospital, 300 Grattan St, Parkville, Victoria, 3050, Australia.; Department of Medicine, University of Melbourne, Eastern Hill Campus, Victoria Parade, Fitzroy, Victoria, 3065, Australia.; Peter MacCallum Cancer Centre, Melbourne, Victoria, 3000, Australia.; Palliative Care Service, St Vincent's Hospital, Victoria Parade, Fitzroy, Victoria, 3065, Australia.
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Źródło:
Current treatment options in oncology [Curr Treat Options Oncol] 2022 Oct; Vol. 23 (10), pp. 1353-1369. Date of Electronic Publication: 2022 Aug 24.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Analgesics, Opioid*/administration & dosage
Pharmacogenetics*
Codeine/administration & dosage ; Cytochrome P-450 CYP2B6/genetics ; Cytochrome P-450 CYP2D6/genetics ; Humans ; Methadone/administration & dosage ; Oxycodone/administration & dosage ; Practice Patterns, Physicians' ; Tramadol/administration & dosage
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 17831

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