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Podgląd okładki
Tytuł :
Pharmacogenomics in Pain Management: A Review of Relevant Gene-Drug Associations and Clinical Considerations.
Autorzy :
Brandl E; Memphis Veterans Affairs Medical Center, Memphis, TN, USA.
Halford Z; Union University College of Pharmacy, Jackson, TN, USA.
Clark MD; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Herndon C; Southern Illinois University Edwardsville School of Pharmacy, Edwardsville, IL, USA.; St Louis University School of Medicine, MO, USA.
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Źródło :
The Annals of pharmacotherapy [Ann Pharmacother] 2021 Dec; Vol. 55 (12), pp. 1486-1501. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Pharmaceutical Preparations*
Pharmacogenetics*
Humans ; Pain/drug therapy ; Pain/genetics ; Pain Management ; Pharmacogenomic Testing
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Profiling of warfarin pharmacokinetics-associated genetic variants: Black Africans portray unique genetic markers important for an African specific warfarin pharmacogenetics-dosing algorithm.
Autorzy :
Ndadza A; Pharmacogenomics and Drug Metabolism Research Group, Division of Human Genetics, Department of Pathology & Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Muyambo S; Department of Clinical Pharmacology, College of Health Science, University of Zimbabwe, Harare, Zimbabwe.; Department of Biological Sciences, Faculty of Science and Engineering, Bindura University of Science and Education, Bindura, Zimbabwe.
Mntla P; Department of Cardiology, Sefako Makgatho Health Sciences University and Dr. George Mukhari Hospital, Pretoria, South Africa.
Wonkam A; Pharmacogenomics and Drug Metabolism Research Group, Division of Human Genetics, Department of Pathology & Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Chimusa E; Pharmacogenomics and Drug Metabolism Research Group, Division of Human Genetics, Department of Pathology & Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Kengne AP; Non-Communicable Diseases Research Unit, South African Medical Research Council and University of Cape Town, Cape Town, South Africa.
Ntsekhe M; Division of Cardiology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Dandara C; Pharmacogenomics and Drug Metabolism Research Group, Division of Human Genetics, Department of Pathology & Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Dec; Vol. 19 (12), pp. 2957-2973. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pharmacogenetics*
Warfarin*
Algorithms ; Anticoagulants ; Blacks ; Cytochrome P-450 CYP2C9/genetics ; Genetic Markers ; Genotype ; Humans ; Vitamin K Epoxide Reductases/genetics
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
An Investigation of the Knowledge Overlap between Pharmacogenomics and Disease Genetics.
Autorzy :
Li B; Department of Biomedical Data Science, Stanford University, 1265 Welch Road, Stanford, CA 94305, USA.
Whirl-Carrillo M
Wright MW
Babb L
Rehm HL
Klein TE
Pokaż więcej
Źródło :
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing [Pac Symp Biocomput] 2022; Vol. 27, pp. 385-396.
Typ publikacji :
Journal Article
MeSH Terms :
Computational Biology*
Pharmacogenetics*
Databases, Factual ; Genetic Testing ; Humans ; Precision Medicine
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Genophenotypic Factors and Pharmacogenomics in Adverse Drug Reactions.
Autorzy :
Cacabelos R; Department of Genomic Medicine, International Center of Neuroscience and Genomic Medicine, EuroEspes Biomedical Research Center, Bergondo, 15165 Corunna, Spain.
Naidoo V; Department of Neuroscience, International Center of Neuroscience and Genomic Medicine, EuroEspes Biomedical Research Center, Bergondo, 15165 Corunna, Spain.
Corzo L; Department of Medical Biochemistry, International Center of Neuroscience and Genomic Medicine, EuroEspes Biomedical Research Center, Bergondo, 15165 Corunna, Spain.
Cacabelos N; Department of Medical Documentation, International Center of Neuroscience and Genomic Medicine, EuroEspes Biomedical Research Center, Bergondo, 15165 Corunna, Spain.
Carril JC; Departments of Genomics and Pharmacogenomics, International Center of Neuroscience and Genomic Medicine, EuroEspes Biomedical Research Center, Bergondo, 15165 Corunna, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 10; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug-Related Side Effects and Adverse Reactions/*genetics
Drug-Related Side Effects and Adverse Reactions/*metabolism
Pharmacogenetics/*trends
Biomarkers ; COVID-19/drug therapy ; Cardiovascular Diseases/drug therapy ; Central Nervous System Diseases/drug therapy ; Cost-Benefit Analysis ; Drug Development ; Genotype ; Humans ; Neoplasms/drug therapy ; Pharmaceutical Preparations ; Pharmacogenetics/methods ; Phenotype
Czasopismo naukowe
Szczegóły Pełny tekst Pełny tekst
Podgląd okładki
Tytuł :
Use of Pharmacogenomics to Guide Proton Pump Inhibitor Therapy in Clinical Practice.
Autorzy :
Harris DM; Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA. .
Stancampiano FF; Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA.
Burton MC; Division of Hospital Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Moyer AM; Department of Laboratory Genetics and Genomics, Mayo Clinic, Rochester, MN, USA.
Schuh MJ; Department of Pharmacy, Mayo Clinic, Jacksonville, FL, USA.
Valery JR; Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA.
Bi Y; Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA.
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Źródło :
Digestive diseases and sciences [Dig Dis Sci] 2021 Dec; Vol. 66 (12), pp. 4120-4127. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Pharmacogenetics*
Pharmacogenomic Variants*
Polymorphism, Genetic*
Cytochrome P-450 CYP2C19/*genetics
Proton Pump Inhibitors/*pharmacokinetics
Algorithms ; Clinical Decision-Making ; Cytochrome P-450 CYP2C19/metabolism ; Decision Support Techniques ; Genotype ; Humans ; Pharmacogenomic Testing ; Phenotype ; Predictive Value of Tests ; Proton Pump Inhibitors/adverse effects ; Race Factors ; Racial Groups/genetics
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Pharmacogenomics insights into precision pediatric oncology.
Autorzy :
Ramos KN; St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, Missouri.
Gregornik D; Children's Minnesota Hospital, University of Minnesota, Minneapolis, Minnesota.
Ramos KS; Institute of Biosciences and Technology, Texas A&M Health, Houston, Texas, USA.
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Źródło :
Current opinion in pediatrics [Curr Opin Pediatr] 2021 Dec 01; Vol. 33 (6), pp. 564-569.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neoplasms*/drug therapy
Neoplasms*/genetics
Pharmacogenetics*
Cardiotoxicity ; Child ; Humans ; Medical Oncology ; Mercaptopurine
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Description of Pharmacogenomic Testing Among Patients Admitted to the Intensive Care Unit After Cardiovascular Surgery.
Autorzy :
Peterson PE; Nursing Research Division, Department of Nursing, Mayo Clinic, Rochester, MN, USA.
Nicholson WT; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.
Moyer AM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Arendt CJ; Department of Pharmacy, Mayo Clinic, Rochester, MN, USA.
Smischney NJ; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.
Seelhammer TG; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.
Krecke CA; Nursing Research Division, Department of Nursing, Mayo Clinic, Rochester, MN, USA.
Haney RM; Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA.
Yaw EJ; Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA.
Chlan LL; Nursing Research Division, Department of Nursing, Mayo Clinic, Rochester, MN, USA.
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Źródło :
Journal of intensive care medicine [J Intensive Care Med] 2021 Nov; Vol. 36 (11), pp. 1281-1285. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article
MeSH Terms :
Pharmacogenetics*
Pharmacogenomic Testing*
Aged ; Cross-Sectional Studies ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Prospective Studies
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Clinical Design and Analysis Strategies for the Development of Gene Therapies: Considerations for Quantitative Drug Development in the Age of Genetic Medicine.
Autorzy :
McIntosh A; Novartis Gene Therapies, Bannockburn, Illinois, USA.
Sverdlov O; Novartis Pharmaceuticals, Cambridge, Massachusetts, USA.
Yu L; Novartis Gene Therapies, Bannockburn, Illinois, USA.
Kaufmann P; Novartis Gene Therapies, Bannockburn, Illinois, USA.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Nov; Vol. 110 (5), pp. 1207-1215. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Clinical Trials as Topic/*methods
Drug Development/*methods
Genetic Therapy/*methods
Pharmacogenetics/*methods
Translational Research, Biomedical/*methods
Drug Development/trends ; Genetic Therapy/trends ; Humans ; Pharmacogenetics/trends ; Translational Research, Biomedical/trends
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Validation of a Large Custom-Designed Pharmacogenomics Panel on an Array Genotyping Platform.
Autorzy :
Tang NY; Department of Pathology, Advanced Technology Clinical Laboratory, The University of Chicago, Chicago, IL.
Pei X; Department of Pathology, Advanced Technology Clinical Laboratory, The University of Chicago, Chicago, IL.
George D; Department of Pathology, Advanced Technology Clinical Laboratory, The University of Chicago, Chicago, IL.
House L; Department of Pathology, Advanced Technology Clinical Laboratory, The University of Chicago, Chicago, IL.
Danahey K; Center for Personalized Therapeutics, The University of Chicago, Chicago, IL.; Center for Research Informatics, The University of Chicago, Chicago, IL.
Lipschultz E; Center for Personalized Therapeutics, The University of Chicago, Chicago, IL.; Center for Research Informatics, The University of Chicago, Chicago, IL.
Ratain MJ; Center for Personalized Therapeutics, The University of Chicago, Chicago, IL.; Department of Medicine, The University of Chicago, Chicago, IL.
O'Donnell PH; Center for Personalized Therapeutics, The University of Chicago, Chicago, IL.; Department of Medicine, The University of Chicago, Chicago, IL.
Yeo KJ; Department of Pathology, Advanced Technology Clinical Laboratory, The University of Chicago, Chicago, IL.; Center for Personalized Therapeutics, The University of Chicago, Chicago, IL.
van Wijk XMR; Department of Pathology, Advanced Technology Clinical Laboratory, The University of Chicago, Chicago, IL.; Center for Personalized Therapeutics, The University of Chicago, Chicago, IL.
Pokaż więcej
Źródło :
The journal of applied laboratory medicine [J Appl Lab Med] 2021 Nov 01; Vol. 6 (6), pp. 1505-1516.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Pharmacogenetics*
Polymorphism, Single Nucleotide*/genetics
Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; Reproducibility of Results
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Pharmacogenomics for Clinical Trials of COVID-19 Medicines: Why Is This Important Now?
Autorzy :
Şardaş S; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Istinye University, Istanbul, Turkey.
Özdemir V; OMICS: A Journal of Integrative Biology, New Rochelle, New York, USA.
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Źródło :
Omics : a journal of integrative biology [OMICS] 2021 Nov; Vol. 25 (11), pp. 679-680. Date of Electronic Publication: 2021 Oct 25.
Typ publikacji :
Editorial
MeSH Terms :
Pandemics*
SARS-CoV-2*
COVID-19/*drug therapy
Pharmacogenetics/*methods
Antiviral Agents/therapeutic use ; COVID-19/genetics ; Clinical Trials as Topic/methods ; Drug Repositioning ; Humans ; Pharmacogenetics/trends ; Precision Medicine ; Proof of Concept Study
Opinia redakcyjna
Szczegóły
Podgląd okładki
Tytuł :
Comparison of clinical pharmacogenetic recommendations across therapeutic areas.
Autorzy :
Shugg T; Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, Michigan.; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Pasternak AL; Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, Michigan.
Luzum JA; Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, Michigan.
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Źródło :
Pharmacogenetics and genomics [Pharmacogenet Genomics] 2022 Feb 01; Vol. 32 (2), pp. 51-59.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Pharmacogenetics*
Pharmacogenomic Testing*
Genetic Markers ; Genetic Testing ; Humans
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Characterization of Pharmacogenetic Information in Food and Drug Administration Drug Labeling and the Table of Pharmacogenetic Associations.
Autorzy :
Cheng CM; First Databank, Inc, South San Francisco, CA, USA.
So TW; First Databank, Inc, South San Francisco, CA, USA.
Bubp JL; First Databank, Inc, South San Francisco, CA, USA.
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Źródło :
The Annals of pharmacotherapy [Ann Pharmacother] 2021 Oct; Vol. 55 (10), pp. 1185-1194. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Drug-Related Side Effects and Adverse Reactions*
Pharmacogenetics*
Cross-Sectional Studies ; Drug Labeling ; Humans ; United States ; United States Food and Drug Administration
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Reviewing pharmacogenetics to advance precision medicine for opioids.
Autorzy :
Magarbeh L; Department of Pharmacology and Toxicology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Centre for Addiction and Mental Health, Toronto, ON, Canada.
Gorbovskaya I; Institute of Medical Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Centre for Addiction and Mental Health, Toronto, ON, Canada.
Le Foll B; Department of Pharmacology and Toxicology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Department of Family and Community Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Centre for Addiction and Mental Health, Toronto, ON, Canada; Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada; Acute Care Program, Centre for Addiction and Mental Health, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Jhirad R; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Office of the Chief Coroner and Ontario Forensic Pathology Service, Toronto, ON, Canada.
Müller DJ; Department of Pharmacology and Toxicology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Institute of Medical Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Centre for Addiction and Mental Health, Toronto, ON, Canada. Electronic address: .
Pokaż więcej
Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Oct; Vol. 142, pp. 112060. Date of Electronic Publication: 2021 Sep 12.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Pharmacogenetics*
Analgesics, Opioid/*administration & dosage
Precision Medicine/*methods
Analgesics, Opioid/pharmacokinetics ; Analgesics, Opioid/pharmacology ; Animals ; Cytochrome P-450 CYP2D6/genetics ; Dose-Response Relationship, Drug ; Humans ; Pain/drug therapy ; Randomized Controlled Trials as Topic ; Receptors, Opioid, mu/genetics
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants.
Autorzy :
Eap CB; Unit of Pharmacogenetics and Clinical Psychopharmacology, Center for Psychiatric Neurosciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Lausanne, Switzerland, Geneva, Switzerland.
Gründer G; Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Baumann P; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Ansermot N; Unit of Pharmacogenetics and Clinical Psychopharmacology, Center for Psychiatric Neurosciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Conca A; Department of Psychiatry, Health Service District Bolzano, Bolzano, Italy.; Department of Child and Adolescent Psychiatry, South Tyrolean Regional Health Service, Bolzano, Italy.
Corruble E; INSERM CESP, Team ≪MOODS≫, Service Hospitalo-Universitaire de Psychiatrie, Universite Paris Saclay, Le Kremlin Bicetre, France.; Service Hospitalo-Universitaire de Psychiatrie, Hôpital Bicêtre, Assistance Publique Hôpitaux de Paris, Le Kremlin Bicêtre, France.
Crettol S; Unit of Pharmacogenetics and Clinical Psychopharmacology, Center for Psychiatric Neurosciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Dahl ML; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
de Leon J; Eastern State Hospital, University of Kentucky Mental Health Research Center, Lexington, KY, USA.
Greiner C; Bundesinstitut für Arzneimittel und Medizinprodukte, Bonn, Germany.
Howes O; King's College London and MRC London Institute of Medical Sciences (LMS)-Imperial College, London, UK.
Kim E; Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, South Korea.; Department of Psychiatry, Seoul National University College of Medicine, Seoul, South Korea.
Lanzenberger R; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Meyer JH; Campbell Family Mental Health Research Institute, CAMH and Department of Psychiatry, University of Toronto, Toronto, Canada.
Moessner R; Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.
Mulder H; Department of Clinical Pharmacy, Wilhelmina Hospital Assen, Assen, The Netherlands.; GGZ Drenthe Mental Health Services Drenthe, Assen, The Netherlands.; Department of Pharmacotherapy, Epidemiology and Economics, Department of Pharmacy and Pharmaceutical Sciences, University of Groningen, Groningen, The Netherlands.; Department of Psychiatry, Interdisciplinary Centre for Psychopathology and Emotion Regulation, University of Groningen, Groningen, The Netherlands.
Müller DJ; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.
Reis M; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.; Clinical Chemistry and Pharmacology, Skåne University Hospital, Lund, Sweden.
Riederer P; Center of Mental Health, Clinic and Policlinic for Psychiatry, Psychosomatics and Psychotherapy, University Hospital Würzburg, Würzburg, Germany.; Department of Psychiatry, University of Southern Denmark Odense, Odense, Denmark.
Ruhe HG; Department of Psychiatry, Radboudumc, Nijmegen, the Netherlands.; Donders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, Netherlands.
Spigset O; Department of Clinical Pharmacology, St. Olav University Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Spina E; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Stegman B; Institut für Pharmazie der Universität Regensburg, Regensburg, Germany.
Steimer W; Institute for Clinical Chemistry and Pathobiochemistry, Technical University of Munich, Munich, Germany.
Stingl J; Institute for Clinical Pharmacology, University Hospital of RWTH Aachen, Germany.
Suzen S; Department of Toxicology, Faculty of Pharmacy, Ankara University, Ankara, Turkey.
Uchida H; Department of Neuropsychiatry, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Unterecker S; Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Würzburg, Germany.
Vandenberghe F; Unit of Pharmacogenetics and Clinical Psychopharmacology, Center for Psychiatric Neurosciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Hiemke C; Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany.
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Źródło :
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry [World J Biol Psychiatry] 2021 Oct; Vol. 22 (8), pp. 561-628. Date of Electronic Publication: 2021 May 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Pharmacogenetics*
Psychiatry*
Antidepressive Agents/pharmacology ; Drug Monitoring ; Humans ; Neuroimaging
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
The L125F MATE1 variant enriched in populations of Amerindian origin is associated with increased plasma levels of metformin and lactate.
Autorzy :
Morales-Rivera MI; Immunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, CDMX, Mexico; Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México, CDMX, Mexico.
Alemón-Medina R; Pharmacology Laboratory, Instituto Nacional de Pediatría, SSA, CDMX, Mexico.
Martínez-Hernández A; Immunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, CDMX, Mexico.
Gómez-Garduño J; Pharmacology Laboratory, Instituto Nacional de Pediatría, SSA, CDMX, Mexico.
Mirzaeicheshmeh E; Immunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, CDMX, Mexico.
Altamirano-Bustamante NF; Endocrinology Department, Instituto Nacional de Pediatría, SSA, CDMX, Mexico.
Ilizaliturri-Flores I; Unidad Profesional Interdisciplinaria de Ingeniería, IPN, Hidalgo, Mexico.
Mendoza-Caamal EC; Immunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, CDMX, Mexico.
Pérez-Guillé MG; Pharmacology Laboratory, Instituto Nacional de Pediatría, SSA, CDMX, Mexico.
García-Álvarez R; Pharmacology Laboratory, Instituto Nacional de Pediatría, SSA, CDMX, Mexico.
Contreras-Cubas C; Immunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, CDMX, Mexico.
Centeno-Cruz F; Immunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, CDMX, Mexico.
Revilla-Monsalve C; Medical Research Unit in Metabolic Diseases, UMAE Hospital de Cardiología, Centro Médico Nacional Siglo XXI, IMSS, CDMX, Mexico.
García-Ortiz H; Immunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, CDMX, Mexico.
Barajas-Olmos F; Immunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, CDMX, Mexico.
Orozco L; Immunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, CDMX, Mexico. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Oct; Vol. 142, pp. 112009. Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
Pharmacogenetics*
Hypoglycemic Agents/*pharmacokinetics
Metformin/*pharmacokinetics
Organic Cation Transport Proteins/*genetics
Adolescent ; Adult ; Child ; Cohort Studies ; Female ; Genetic Variation ; Genotype ; Humans ; Indians, North American/genetics ; Lactic Acid/blood ; Male ; Mexico ; Molecular Dynamics Simulation
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Elucidating the role of pharmacogenetics in irinotecan efficacy and adverse events in metastatic colorectal cancer patients.
Autorzy :
Riera P; Pharmacy Department, Hospital De La Santa Creu I Sant Pau, Barcelona, Spain.; U705, Isciii Center for Biomedical Research on Rare Diseases (Ciberer), Barcelona, Spain.
Páez D; U705, Isciii Center for Biomedical Research on Rare Diseases (Ciberer), Barcelona, Spain.; Medical Oncology Department, Hospital De La Santa Creu I Sant Pau, Barcelona, Spain.
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Źródło :
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2021 Oct; Vol. 17 (10), pp. 1157-1163. Date of Electronic Publication: 2021 Sep 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Pharmacogenetics*
Colorectal Neoplasms/*drug therapy
Irinotecan/*administration & dosage
Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Diarrhea/chemically induced ; Dose-Response Relationship, Drug ; Genotype ; Glucuronosyltransferase/genetics ; Humans ; Irinotecan/adverse effects ; Neutropenia/chemically induced ; Precision Medicine ; Topoisomerase I Inhibitors/administration & dosage ; Topoisomerase I Inhibitors/adverse effects
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Pharmacist-Led Medication Evaluation Considering Pharmacogenomics and Drug-Induced Phenoconversion in the Treatment of Multiple Comorbidities: A Case Report.
Autorzy :
Del Toro-Pagán NM; Office of Translational Research and Residency Programs, Tabula Rasa HealthCare, Moorestown, NJ 08057, USA.
Matos A; Office of Translational Research and Residency Programs, Tabula Rasa HealthCare, Moorestown, NJ 08057, USA.
Thacker D; Precision Pharmacotherapy Research & Development Institute, Tabula Rasa HealthCare, Orlando, FL 32827, USA.
Turgeon J; Precision Pharmacotherapy Research & Development Institute, Tabula Rasa HealthCare, Orlando, FL 32827, USA.; Faculty of Pharmacy, Université de Montréal, Montréal, QC H3C 3J7, Canada.
Amin NS; Office of Translational Research and Residency Programs, Tabula Rasa HealthCare, Moorestown, NJ 08057, USA.
Michaud V; Precision Pharmacotherapy Research & Development Institute, Tabula Rasa HealthCare, Orlando, FL 32827, USA.; Faculty of Pharmacy, Université de Montréal, Montréal, QC H3C 3J7, Canada.
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Źródło :
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2021 Sep 10; Vol. 57 (9). Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Case Reports
MeSH Terms :
Pharmaceutical Preparations*
Pharmacogenetics*
Cytochrome P-450 CYP2D6 ; Humans ; Pharmacists ; Quality of Life
Raport
Szczegóły
Podgląd okładki
Tytuł :
Pharmacogenetic-based management of depression: Role of traditional Persian medicine.
Autorzy :
Jalali A; Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Firouzabadi N; Department of Pharmacology & Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Zarshenas MM; Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Sep; Vol. 35 (9), pp. 5031-5052. Date of Electronic Publication: 2021 May 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Depression*/drug therapy
Depression*/genetics
Pharmacogenetics*
Phytotherapy*
Humans ; Medicine, Traditional ; Plants, Medicinal
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Cyclophosphamide bioactivation pharmacogenetics in breast cancer patients.
Autorzy :
Helsby N; Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. .
Yong M; Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Burns K; Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Findlay M; Cancer Trials New Zealand, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.; Auckland Regional Cancer and Blood Service, Auckland City Hospital, Grafton, Auckland, New Zealand.
Porter D; Auckland Regional Cancer and Blood Service, Auckland City Hospital, Grafton, Auckland, New Zealand.
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Źródło :
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2021 Sep; Vol. 88 (3), pp. 533-542. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pharmacogenetics*
Breast Neoplasms/*drug therapy
Cyclophosphamide/*administration & dosage
Cytochrome P-450 CYP2C19/*genetics
Adult ; Aged ; Antineoplastic Agents, Alkylating/administration & dosage ; Antineoplastic Agents, Alkylating/pharmacokinetics ; Antineoplastic Agents, Alkylating/pharmacology ; Breast Neoplasms/genetics ; Cyclophosphamide/analogs & derivatives ; Cyclophosphamide/metabolism ; Cyclophosphamide/pharmacokinetics ; Cyclophosphamide/pharmacology ; Cytochrome P-450 CYP2B6/genetics ; Dose-Response Relationship, Drug ; Female ; Genotype ; Humans ; Middle Aged ; Polymorphism, Single Nucleotide ; Young Adult
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
Genotyping HLA alleles to predict the development of Severe cutaneous adverse drug reactions (SCARs): state-of-the-art.
Autorzy :
Jantararoungtong T; Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.; Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand.
Tempark T; Division of Dermatology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Koomdee N; Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.; Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand.
Medhasi S; Center of Medical Genomics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Sukasem C; Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.; Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand.; Preventive Genomics and Family Check-up Services Center, Bumrungrad International Hospital, Bangkok, Thailand.
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Źródło :
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2021 Sep; Vol. 17 (9), pp. 1049-1064. Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Pharmacogenetics*
Drug Eruptions/*genetics
HLA Antigens/*genetics
Acute Generalized Exanthematous Pustulosis/genetics ; Acute Generalized Exanthematous Pustulosis/physiopathology ; Alleles ; Cost-Benefit Analysis ; Drug Eruptions/physiopathology ; Drug Hypersensitivity Syndrome/genetics ; Drug Hypersensitivity Syndrome/physiopathology ; Genotype ; Humans ; Mass Screening ; Stevens-Johnson Syndrome/genetics ; Stevens-Johnson Syndrome/physiopathology
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 36199

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