Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Pharmacology"" wg kryterium: Temat


Starter badań:

Tytuł:
Hallmarks of neurodegenerative disease: A systems pharmacology perspective.
Autorzy:
Bloomingdale P; Quantitative Pharmacology and Pharmacometrics, Merck & Co., Inc., Boston, Massachusetts, USA.
Karelina T; InSysBio, Moscow, Russia.
Ramakrishnan V; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
Bakshi S; Certara QSP, Oss, The Netherlands.; Certara QSP, Princeton, New Jersey, USA.
Véronneau-Veilleux F; Faculté de Pharmacie, University of Montreal, Montreal, Quebec, Canada.
Moye M; Quantitative Pharmacology and Pharmacometrics, Merck & Co., Inc., Boston, Massachusetts, USA.
Sekiguchi K; Shionogi & Co., Ltd., Osaka, Japan.; SUNY Downstate Medical Center, New York, New York, USA.
Meno-Tetang G; Neuroscience, Biopharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Mohan A; Vantage Research, Chennai, Tamil Nadu, India.
Maithreye R; Vantage Research, Chennai, Tamil Nadu, India.
Thomas VA; Amgen, South San Francisco, California, USA.
Gibbons F; Clinical Pharmacology and Pharmacometrics, Biogen, Cambridge, Massachusetts, USA.
Cabal A; Eisai, Nutley, New Jersey, USA.
Bouteiller JM; Center for Neural Engineering, Department of Biomedical Engineering at the Viterbi School of Engineering, Los Angeles, California, USA.; Institute for Technology and Medical Systems Innovation, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Geerts H; Certara QSP, Oss, The Netherlands.
Pokaż więcej
Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2022 Nov; Vol. 11 (11), pp. 1399-1429. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neurodegenerative Diseases*/drug therapy
Parkinson Disease*/drug therapy
Pharmacology*
Humans ; Network Pharmacology ; Disease Progression ; Models, Theoretical
Czasopismo naukowe
Tytuł:
Development of and insights from systems pharmacology models of antibody-drug conjugates.
Autorzy:
Lam I; Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Pilla Reddy V; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Ball K; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Arends RH; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
Mac Gabhann F; Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Pokaż więcej
Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2022 Aug; Vol. 11 (8), pp. 967-990. Date of Electronic Publication: 2022 Jul 03.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunoconjugates*/pharmacokinetics
Pharmacology*
Humans ; Models, Biological ; Network Pharmacology
Czasopismo naukowe
Tytuł:
Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model.
Autorzy:
Ruiz-Martinez A; Department of Biomedical Engineering, Johns Hopkins, University School of Medicine, Baltimore, Maryland, United States of America.
Gong C; Department of Biomedical Engineering, Johns Hopkins, University School of Medicine, Baltimore, Maryland, United States of America.
Wang H; Department of Biomedical Engineering, Johns Hopkins, University School of Medicine, Baltimore, Maryland, United States of America.
Sové RJ; Department of Biomedical Engineering, Johns Hopkins, University School of Medicine, Baltimore, Maryland, United States of America.
Mi H; Department of Biomedical Engineering, Johns Hopkins, University School of Medicine, Baltimore, Maryland, United States of America.
Kimko H; Clinical Pharmacology & Quantitative Pharmacology, AstraZeneca, Gaithersburg, Maryland, United States of America.
Popel AS; Department of Biomedical Engineering, Johns Hopkins, University School of Medicine, Baltimore, Maryland, United States of America.; Department of Oncology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America.
Pokaż więcej
Źródło:
PLoS computational biology [PLoS Comput Biol] 2022 Jul 22; Vol. 18 (7), pp. e1010254. Date of Electronic Publication: 2022 Jul 22 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Neoplasms*/therapy
Pharmacology*/methods
Combined Modality Therapy ; Humans ; Immunotherapy/methods ; Models, Biological ; Network Pharmacology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Quantitative system pharmacology as a legitimate approach to examine extrapolation strategies used to support pediatric drug development.
Autorzy:
Azer K; Axcella Therapeutics, Cambridge, Massachusetts, USA.
Barrett JS; Critical Path Institute, Tucson, Arizona, USA.
Pokaż więcej
Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2022 Jul; Vol. 11 (7), pp. 797-804. Date of Electronic Publication: 2022 May 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Drug Development*
Pharmacology*
Adult ; Benchmarking ; Child ; Drug Discovery ; Humans ; Models, Biological ; Network Pharmacology ; Research Design
Czasopismo naukowe
Tytuł:
The Mechanism of Crocetin Targeting Cardiovascular Disease Based on Network Pharmacology Constrained by Spectral Experiments.
Autorzy:
Geng Z; College of Chemistry and Materials Engineering, Zhejiang Agriculture & Forestry University, Hangzhou, Zhejiang, 311300, China.
Guo M; College of Chemistry and Materials Engineering, Zhejiang Agriculture & Forestry University, Hangzhou, Zhejiang, 311300, China.
Zhou Q; College of Chemistry and Materials Engineering, Zhejiang Agriculture & Forestry University, Hangzhou, Zhejiang, 311300, China.
Pan L; College of Forestry and Biotechnology, Zhejiang Agriculture & Forestry University, Hangzhou Zhejiang, 311300, China.
Pokaż więcej
Źródło:
Chemistry & biodiversity [Chem Biodivers] 2022 Nov; Vol. 19 (11), pp. e202200685. Date of Electronic Publication: 2022 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiovascular Diseases*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Humans ; Molecular Docking Simulation ; Network Pharmacology ; Carotenoids/pharmacology ; Carotenoids/chemistry ; Medicine, Chinese Traditional ; Receptor, Muscarinic M1 ; Receptors, Adrenergic, alpha-1
Czasopismo naukowe
Tytuł:
Exploration of molecular targets and mechanisms of Chinese medicinal formula Acacia Catechu -Scutellariae Radix in the treatment of COVID-19 by a systems pharmacology strategy.
Autorzy:
Feng T; Department of Chinese Materia Medica and Natural Medicines, School of Pharmacy, Air Force Medical University, Xi'an, China.
Zhang M; Department of Chinese Materia Medica and Natural Medicines, School of Pharmacy, Air Force Medical University, Xi'an, China.
Xu Q; Department of Chinese Materia Medica and Natural Medicines, School of Pharmacy, Air Force Medical University, Xi'an, China.
Song F; Department of Chinese Materia Medica and Natural Medicines, School of Pharmacy, Air Force Medical University, Xi'an, China.
Wang L; School of Medicine, Shaanxi Energy Institute, Xianyang, China.
Gai S; Department of Chinese Materia Medica and Natural Medicines, School of Pharmacy, Air Force Medical University, Xi'an, China.
Tang H; Department of Chinese Materia Medica and Natural Medicines, School of Pharmacy, Air Force Medical University, Xi'an, China.
Wang S; Department of Chinese Materia Medica and Natural Medicines, School of Pharmacy, Air Force Medical University, Xi'an, China.; College of Life Science and Medicine, Northwest University, Xi'an, China.
Zhou L; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Li H; Department of Chinese Materia Medica and Natural Medicines, School of Pharmacy, Air Force Medical University, Xi'an, China.
Pokaż więcej
Źródło:
Phytotherapy research : PTR [Phytother Res] 2022 Nov; Vol. 36 (11), pp. 4210-4229. Date of Electronic Publication: 2022 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/drug therapy
Acacia*
Catechin*
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Humans ; SARS-CoV-2 ; Scutellaria baicalensis ; Molecular Docking Simulation ; Quercetin/pharmacology ; Quercetin/therapeutic use ; Network Pharmacology ; Phosphatidylinositol 3-Kinases ; Medicine, Chinese Traditional
Czasopismo naukowe
Tytuł:
Network Pharmacology Analysis and Experimental Validation of Kaempferol in the Treatment of Ischemic Stroke by Inhibiting Apoptosis and Regulating Neuroinflammation Involving Neutrophils.
Autorzy:
Zhang SS; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.; Beijing Key Laboratory of Drug Target Identification and New Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.
Liu M; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.; Beijing Key Laboratory of Drug Target Identification and New Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.
Liu DN; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.; Beijing Key Laboratory of Drug Target Identification and New Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.
Shang YF; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.; Beijing Key Laboratory of Drug Target Identification and New Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.
Du GH; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.; Beijing Key Laboratory of Drug Target Identification and New Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.
Wang YH; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.; Beijing Key Laboratory of Drug Target Identification and New Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100006, China.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 21; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Ischemic Stroke*
Brain Ischemia*/drug therapy
Brain Ischemia*/metabolism
Animals ; Rats ; Kaempferols/pharmacology ; Kaempferols/therapeutic use ; Neutrophils/metabolism ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Toll-Like Receptor 4/metabolism ; Cyclooxygenase 2/metabolism ; Myeloid Differentiation Factor 88/metabolism ; Brain-Derived Neurotrophic Factor/metabolism ; Neuroinflammatory Diseases ; Network Pharmacology ; Apoptosis Regulatory Proteins/metabolism
Czasopismo naukowe
Tytuł:
Pingyin rose essential oil alleviates LPS-Induced inflammation in RAW 264.7 cells via the NF-κB pathway: an integrated in vitro and network pharmacology analysis.
Autorzy:
Raka RN; Beijing Engineering and Technology Research Center of Food Additives, College of Food and Health, Beijing Technology and Business University, Building No. 8, Fucheng Road 11#, Haidian District, (BTBU), Beijing, 100048, China.
Zhiqian D; Beijing Engineering and Technology Research Center of Food Additives, College of Food and Health, Beijing Technology and Business University, Building No. 8, Fucheng Road 11#, Haidian District, (BTBU), Beijing, 100048, China.
Yue Y; College of Chemical and Materials Engineering, Beijing Technology and Business University, Building No. 1, Fucheng Road 11#, Haidian District, Beijing, 100048, China.
Luchang Q; College of Chemical and Materials Engineering, Beijing Technology and Business University, Building No. 1, Fucheng Road 11#, Haidian District, Beijing, 100048, China.
Suyeon P; College of Chemical and Materials Engineering, Beijing Technology and Business University, Building No. 1, Fucheng Road 11#, Haidian District, Beijing, 100048, China.
Junsong X; Beijing Engineering and Technology Research Center of Food Additives, College of Food and Health, Beijing Technology and Business University, Building No. 8, Fucheng Road 11#, Haidian District, (BTBU), Beijing, 100048, China. .
Hua W; College of Chemical and Materials Engineering, Beijing Technology and Business University, Building No. 1, Fucheng Road 11#, Haidian District, Beijing, 100048, China. .
Pokaż więcej
Źródło:
BMC complementary medicine and therapies [BMC Complement Med Ther] 2022 Oct 14; Vol. 22 (1), pp. 272. Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Oils, Volatile*/pharmacology
Rosa*/metabolism
Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Farnesol/adverse effects ; Inflammation/metabolism ; Lipopolysaccharides/adverse effects ; Mice ; Molecular Docking Simulation ; Monoterpenes ; NF-kappa B/metabolism ; Network Pharmacology ; RAW 264.7 Cells ; Reactive Oxygen Species ; Superoxide Dismutase
Czasopismo naukowe
Tytuł:
Integrated LC-MS/MS method and network pharmacology for exploring the characterization and mechanism of neuroprotective effect of Vitis amurensis Rupr. wine polyphenol.
Autorzy:
Zhang Y; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.
Yuan D; Jiangsu Haosen Pharmaceutical Group Co., Ltd, Lianyungang, China.
Guo J; School of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, China.
Jiang J; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Yao H; School of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, China.
Chen Z; School of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, China.
Li L; School of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, China.
Cui Y; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.
Pokaż więcej
Źródło:
Journal of food biochemistry [J Food Biochem] 2022 Oct; Vol. 46 (10), pp. e14316. Date of Electronic Publication: 2022 Jul 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuroprotective Agents*/analysis
Neuroprotective Agents*/pharmacology
Proanthocyanidins*/analysis
Vitis*
Wine*/analysis
Anthocyanins/analysis ; Chromatography, Liquid ; ErbB Receptors/analysis ; Flavonoids/analysis ; Flavonoids/pharmacology ; Network Pharmacology ; Phenols/analysis ; Phosphatidylinositol 3-Kinases ; Polyphenols/analysis ; Polyphenols/pharmacology ; Proto-Oncogene Proteins c-akt ; Quercetin ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł:
Exploring the Therapeutic Effects of Black Ginseng on Non-Alcoholic Fatty Liver Disease by Using Network Pharmacology and Molecular Docking.
Autorzy:
Wei W; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130117, China.
Liu L; College of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin, 132101, China.
Liu X; School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, 130117, China.
Tao Y; School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, 130117, China.
Zhao X; Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China.; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China.
Gong J; School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, 130117, China.
Wang Y; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130117, China.
Liu S; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130117, China.
Pokaż więcej
Źródło:
Chemistry & biodiversity [Chem Biodivers] 2022 Oct; Vol. 19 (10), pp. e202200719. Date of Electronic Publication: 2022 Sep 23.
Typ publikacji:
Journal Article
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/drug therapy
Panax*/metabolism
Ginsenosides*/pharmacology
Ginsenosides*/therapeutic use
Choline Deficiency*/metabolism
Choline Deficiency*/pathology
Mice ; Animals ; Alanine Transaminase ; Molecular Docking Simulation ; Proto-Oncogene Proteins c-akt/metabolism ; Network Pharmacology ; Aspartate Aminotransferases ; Liver ; Methionine/metabolism ; Methionine/pharmacology
Czasopismo naukowe
Tytuł:
Multi-scale mechanism of antiviral drug-alike phytoligands from Ayurveda in managing COVID-19 and associated metabolic comorbidities: insights from network pharmacology.
Autorzy:
Choudhary N; Centre for Computational Biology and Bioinformatics, School of Life Sciences, Central University of Himachal Pradesh, Dharamshala, 176206, India.
Singh V; Centre for Computational Biology and Bioinformatics, School of Life Sciences, Central University of Himachal Pradesh, Dharamshala, 176206, India. .
Pokaż więcej
Źródło:
Molecular diversity [Mol Divers] 2022 Oct; Vol. 26 (5), pp. 2575-2594. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/chemistry
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
COVID-19*/drug therapy
Comorbidity ; Humans ; Molecular Docking Simulation ; Network Pharmacology ; Phytochemicals/pharmacology ; SARS-CoV-2
Czasopismo naukowe
Tytuł:
The potential mechanism of Bupleurum against anxiety was predicted by network pharmacology study and molecular docking.
Autorzy:
Wu HB; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Xiao YG; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Chen JS; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Qiu ZK; Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China. .
Pokaż więcej
Źródło:
Metabolic brain disease [Metab Brain Dis] 2022 Jun; Vol. 37 (5), pp. 1609-1639. Date of Electronic Publication: 2022 Apr 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Anxiety Agents*/pharmacology
Anti-Anxiety Agents*/therapeutic use
Bupleurum*
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Stigmasterol/*pharmacology
Anxiety/drug therapy ; Molecular Docking Simulation ; Network Pharmacology ; Stigmasterol/chemistry
Czasopismo naukowe
Tytuł:
Exploring the mechanisms of Gui Zhi Fu Ling Wan on varicocele via network pharmacology and molecular docking.
Autorzy:
Wang R; Department of Surgery, The Third Hospital of Guangdong Medical University (Longjiang Hospital of Shunde District), Foshan, China.
Qiao X; Department of Gynecology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Wang X; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Pokaż więcej
Źródło:
Andrologia [Andrologia] 2022 Dec; Vol. 54 (11), pp. e14635. Date of Electronic Publication: 2022 Nov 13.
Typ publikacji:
Journal Article
MeSH Terms:
Varicocele*/drug therapy
Varicocele*/genetics
Cinnamomum aromaticum*
Wolfiporia*
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Male ; Humans ; Molecular Docking Simulation ; Vascular Endothelial Growth Factor A ; Network Pharmacology ; Phosphatidylinositol 3-Kinases ; Medicine, Chinese Traditional ; Cyclooxygenase 2
Czasopismo naukowe
Tytuł:
Study on the mechanism of anti-acute lung injury of Shuanghuanglian oral liquid based on identification of transitional components in blood and network pharmacology.
Autorzy:
Li R; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Zhu Y; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yu M; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Liu T; School of Pharmacy, Shenyang Medical College, Shenyang 110034, China.
Zhao Y; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: .
Yu Z; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: .
Pokaż więcej
Źródło:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2022 Dec 01; Vol. 1212, pp. 123498. Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal*/pharmacology
Acute Lung Injury*/drug therapy
Rats ; Animals ; Follow-Up Studies ; Network Pharmacology ; Phosphatidylinositol 3-Kinases ; Medicine, Chinese Traditional
Czasopismo naukowe
Tytuł:
The mechanism of triptolide in the treatment of connective tissue disease-related interstitial lung disease based on network pharmacology and molecular docking.
Autorzy:
Zhu W; Department of Rheumatology, Nanjing University of Chinese Medicine, Nanjing, China.
Li Y; Department of Pneumology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.; Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Zhao J; Department of Rheumatology, Nanjing University of Chinese Medicine, Nanjing, China.
Wang Y; Department of Rheumatology, Nanjing University of Chinese Medicine, Nanjing, China.; Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Li Y; Department of Rheumatology, Nanjing University of Chinese Medicine, Nanjing, China.; Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Wang Y; Department of Rheumatology, Nanjing University of Chinese Medicine, Nanjing, China.; Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Pokaż więcej
Źródło:
Annals of medicine [Ann Med] 2022 Dec; Vol. 54 (1), pp. 541-552.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Connective Tissue Diseases*
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Lung Diseases, Interstitial*/drug therapy
Diterpenes ; Epoxy Compounds ; Humans ; Molecular Docking Simulation ; Network Pharmacology ; Phenanthrenes ; Phosphatidylinositol 3-Kinases
Czasopismo naukowe
Tytuł:
A quantitative systems pharmacology model for simulating OFF-Time in augmentation trials for Parkinson's disease: application to preladenant.
Autorzy:
Rose R; Certara QSP-UK, Canterbury Innovation Centre, University Road, Canterbury, CT2 7FG, UK.
Mitchell E; Certara QSP-UK, Canterbury Innovation Centre, University Road, Canterbury, CT2 7FG, UK.
Van Der Graaf P; Certara QSP-UK, Canterbury Innovation Centre, University Road, Canterbury, CT2 7FG, UK.
Takaichi D; Kyowa-Kirin, 1-9-2 Otemachi, Chiyoda-ku, Tokyo, 100-0004, Japan.
Hosogi J; Kyowa-Kirin, 1-9-2 Otemachi, Chiyoda-ku, Tokyo, 100-0004, Japan.
Geerts H; Certara QSP-US, Westwind Dr 686, Berwyn, PA, 19312, USA. .
Pokaż więcej
Źródło:
Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2022 Dec; Vol. 49 (6), pp. 593-606. Date of Electronic Publication: 2022 Oct 09.
Typ publikacji:
Journal Article
MeSH Terms:
Levodopa*/pharmacology
Parkinson Disease*/drug therapy
Humans ; Antiparkinson Agents/pharmacology ; Antiparkinson Agents/therapeutic use ; Network Pharmacology
Czasopismo naukowe
Tytuł:
A network pharmacology approach to predict potential targets and mechanisms of " Ramulus Cinnamomi (cassiae) - Paeonia lactiflora " herb pair in the treatment of chronic pain with comorbid anxiety and depression.
Autorzy:
Pan HT; Acupuncture Anesthesia Clinical Research Institute, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xi ZQ; Acupuncture Anesthesia Clinical Research Institute, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wei XQ; Acupuncture Anesthesia Clinical Research Institute, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wang K; Acupuncture Anesthesia Clinical Research Institute, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Pokaż więcej
Źródło:
Annals of medicine [Ann Med] 2022 Dec; Vol. 54 (1), pp. 413-425.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chronic Pain*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Paeonia*
Anxiety/complications ; Anxiety/drug therapy ; Anxiety Disorders/drug therapy ; Depression/complications ; Depression/drug therapy ; Humans ; Network Pharmacology
Czasopismo naukowe
Tytuł:
Mechanism of lily bulb and Rehmannia decoction in the treatment of lipopolysaccharide-induced depression-like rats based on metabolomics study and network pharmacology.
Autorzy:
Chi X; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, PR China.
Xue X; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Pan J; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Wu J; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Shi H; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Wang Y; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Lu Y; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Zhang Z; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Ma K; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Pokaż więcej
Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 1850-1864.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Lilium*
Rehmannia*
Animals ; Antidepressive Agents/pharmacology ; Cytokines ; Depression/chemically induced ; Depression/drug therapy ; Endocannabinoids ; Fluoxetine ; Glycosylphosphatidylinositols ; Hormones ; Interleukin-6 ; Lipopolysaccharides/toxicity ; Metabolomics/methods ; Network Pharmacology ; Plant Extracts ; Rats ; Serotonin ; Tumor Necrosis Factor-alpha ; gamma-Aminobutyric Acid
Czasopismo naukowe
Tytuł:
Exploring the pharmacological mechanism of Shengjing capsule on male infertility by a network pharmacology approach.
Autorzy:
Wang M; Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
Wang Q; Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Jiang H; Department of Reproductive Medicine Center, Peking University Third Hospital, Beijing, 100191, China.; Department of Andrology, Peking University Third Hospital, Beijing, 100191, China.
Du Y; Fuyang People's Hospital, Anhui Medical University, Fuyang, 236000, Anhui, China.
Zhang X; Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China. .
Pokaż więcej
Źródło:
BMC complementary medicine and therapies [BMC Complement Med Ther] 2022 Nov 18; Vol. 22 (1), pp. 299. Date of Electronic Publication: 2022 Nov 18.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Infertility, Male*/drug therapy
Humans ; Male ; Network Pharmacology ; Medicine, Chinese Traditional/methods ; DEAD-box RNA Helicases
Czasopismo naukowe
Tytuł:
Biochemical Targets and Molecular Mechanism of Ginsenoside Compound K in Treating Osteoporosis Based on Network Pharmacology.
Autorzy:
Zhang S; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China.; Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an 710069, China.; Biotech. & Biomed. Research Institute, Northwest University, Xi'an 710069, China.
Shen S; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China.; Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an 710069, China.; Biotech. & Biomed. Research Institute, Northwest University, Xi'an 710069, China.
Ma P; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China.; Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an 710069, China.; Biotech. & Biomed. Research Institute, Northwest University, Xi'an 710069, China.
Fan D; Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China.; Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi'an 710069, China.; Biotech. & Biomed. Research Institute, Northwest University, Xi'an 710069, China.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 11; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Ginsenosides*/pharmacology
Ginsenosides*/therapeutic use
Osteoporosis*/drug therapy
Humans ; Molecular Docking Simulation ; Phosphatidylinositol 3-Kinases ; Network Pharmacology
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies

Prześlij opinię

Twoje opinie są dla nas bardzo ważne i mogą być niezwykle pomocne w pokazaniu nam, gdzie możemy dokonać ulepszeń. Bylibyśmy bardzo wdzięczni za poświęcenie kilku chwil na wypełnienie krótkiego formularza.

Formularz