Temat: "Pharmacology" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Systematic analysis of the material basis and mechanism of total saponins of mountain cultivated ginseng against doxorubicin-induced cardiotoxicity based on integrating network pharmacology and in vivo substance profiling.
Autorzy:: Liu H; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Zhang H; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Nie J; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Yu Y; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Li Q; Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Lv C; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Lu J; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.; Pokaż więcej
Źródło:: Phytochemical analysis : PCA [Phytochem Anal] 2023 Oct; Vol. 34 (7), pp. 755-771. Date of Electronic Publication: 2022 Dec 18.
Typ publikacji:: Journal Article
MeSH Terms:: Saponins*/pharmacology
Ginsenosides*/pharmacology
Panax*/chemistry
Cardiotoxicity ; Molecular Docking Simulation ; Network Pharmacology ; Doxorubicin/pharmacology ; Doxorubicin/metabolism

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Skocz do pozycji: 2.

Tytuł:: Exploring the mechanism by which quercetin re-sensitizes breast cancer to paclitaxel: network pharmacology, molecular docking, and experimental verification.
Autorzy:: Yang Y; Department of Basic Clinical Laboratory Medicine, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, China.
Yan J; Department of Basic Clinical Laboratory Medicine, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, China.
Huang J; Center for Clinical Laboratories, the Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, China.
Wu X; Department of Basic Clinical Laboratory Medicine, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, China.
Yuan Y; Department of Basic Clinical Laboratory Medicine, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, China.
Yuan Y; Department of Clinical Laboratory, The First People's Hospital of Guiyang, Guiyang, 550002, China.
Zhang S; Department of Basic Clinical Laboratory Medicine, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, China. .; Center for Clinical Laboratories, the Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, China. .
Mo F; Department of Basic Clinical Laboratory Medicine, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, China. .; Center for Clinical Laboratories, the Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, China. .; Pokaż więcej
Źródło:: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2023 Nov; Vol. 396 (11), pp. 3045-3059. Date of Electronic Publication: 2023 May 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Paclitaxel*/pharmacology
Neoplasms*
Molecular Docking Simulation ; Quercetin/pharmacology ; Network Pharmacology ; ErbB Receptors

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Skocz do pozycji: 3.

Tytuł:: Protective effect of liriodendrin on IgG immune complex-induced acute lung injury via inhibiting SRC/STAT3/MAPK signaling pathway: a network pharmacology research.
Autorzy:: Zhang S; Graduate School, Tianjin Medical University, Tianjin, China.
Hu D; Graduate School, Tianjin Medical University, Tianjin, China.
Zhuo Y; Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Tianjin Nankai Hospital, Tianjin, China.
Cui L; Graduate School, Tianjin Medical University, Tianjin, China.
Li D; Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Tianjin Nankai Hospital, Tianjin, China.
Zhang L; Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Tianjin Nankai Hospital, Tianjin, China.
Yang L; Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Tianjin Nankai Hospital, Tianjin, China. .
Wang X; Graduate School, Tianjin Medical University, Tianjin, China. .; Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Tianjin Nankai Hospital, Tianjin, China. .; Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair, Institute of Integrative Medicine for Acute Abdominal Diseases, Tianjin University, Tianjin, China. .; Pokaż więcej
Źródło:: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2023 Nov; Vol. 396 (11), pp. 3269-3283. Date of Electronic Publication: 2023 May 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antigen-Antibody Complex*/pharmacology
Antigen-Antibody Complex*/therapeutic use
Acute Lung Injury*/drug therapy
Acute Lung Injury*/prevention & control
Acute Lung Injury*/etiology
Mice ; Animals ; Interleukin-6 ; Tumor Necrosis Factor-alpha/pharmacology ; Molecular Docking Simulation ; Network Pharmacology ; Signal Transduction ; Lung/pathology ; Cytokines/metabolism ; Immunoglobulin G/pharmacology ; Immunoglobulin G/therapeutic use ; Lipopolysaccharides/pharmacology

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Skocz do pozycji: 4.

Tytuł:: Anti-atherosclerotic effects of naringenin and quercetin from Folium Artemisiae argyi by attenuating Interleukin-1 beta (IL-1β)/ matrix metalloproteinase 9 (MMP9): network pharmacology-based analysis and validation.
Autorzy:: Zhang L; Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Huanggang Normal University, Huanggang, 438000, China.; Hubei Collaborative Innovation Center for the Characteristic Resources Exploitation of Dabie Mountains, Huanggang Normal University, Huanggang, 438000, China.
Yang Z; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.; Tianjin Key Laboratory of Translational Research of TCM Prescription and Syndrome, Tianjin, China.
Li X; Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Huanggang Normal University, Huanggang, 438000, China.
Hua Y; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.; Tianjin Key Laboratory of Translational Research of TCM Prescription and Syndrome, Tianjin, China.
Fan G; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.; Tianjin Key Laboratory of Translational Research of TCM Prescription and Syndrome, Tianjin, China.
He F; Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Huanggang Normal University, Huanggang, 438000, China. .; Hubei Collaborative Innovation Center for the Characteristic Resources Exploitation of Dabie Mountains, Huanggang Normal University, Huanggang, 438000, China. .; Pokaż więcej
Źródło:: BMC complementary medicine and therapies [BMC Complement Med Ther] 2023 Oct 25; Vol. 23 (1), pp. 378. Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:: Journal Article
MeSH Terms:: Drugs, Chinese Herbal*/pharmacology
Atherosclerosis*/drug therapy
Humans ; Matrix Metalloproteinase 9 ; Quercetin/pharmacology ; Network Pharmacology ; Interleukin-1beta ; Molecular Docking Simulation ; Vascular Endothelial Growth Factor A ; Interleukin-6

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Skocz do pozycji: 5.

Tytuł:: Anti-Inflammatory and Antioxidant Activities of Lipophilic Fraction from Liriope platyphylla Seeds Using Network Pharmacology, Molecular Docking, and In Vitro Experiments.
Autorzy:: Truong VL; School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.; Food and Bio-Industry Research Institute, School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Bae YJ; School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Rarison RHG; School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Bang JH; School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Park SY; School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Jeong WS; School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.; Food and Bio-Industry Research Institute, School of Food Science & Biotechnology, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 06; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants*/pharmacology
Antioxidants*/therapeutic use
Nitric Oxide*/metabolism
Molecular Docking Simulation ; Kelch-Like ECH-Associated Protein 1/metabolism ; Network Pharmacology ; NF-E2-Related Factor 2/metabolism ; Anti-Inflammatory Agents/therapeutic use ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use

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Skocz do pozycji: 6.

Tytuł:: Identification of quality markers for Cyanotis arachnoidea and analysis of its physiological mechanism based on chemical pattern recognition, network pharmacology, and experimental validation.
Autorzy:: Hu J; Hebei University of Chinese Medicine, Shijiazhuang, China.
Feng Y; Hebei University of Chinese Medicine, Shijiazhuang, China.
Li B; Hebei University of Chinese Medicine, Shijiazhuang, China.
Wang F; Hebei University of Chinese Medicine, Shijiazhuang, China.
Qian Q; Hebei University of Chinese Medicine, Shijiazhuang, China.; Hebei Traditional Chinese Medicine Formula Granule Engineering & Technology Innovate Center, Shijiazhuang, China.; Quality Evaluation & Standardization Hebei Province Engineering Research Center of Traditional Chinese Medicine, Shijiazhuang, China.
Tian W; Hebei University of Chinese Medicine, Shijiazhuang, China.; Hebei Traditional Chinese Medicine Formula Granule Engineering & Technology Innovate Center, Shijiazhuang, China.; Quality Evaluation & Standardization Hebei Province Engineering Research Center of Traditional Chinese Medicine, Shijiazhuang, China.
Niu L; Hebei University of Chinese Medicine, Shijiazhuang, China.; Hebei Traditional Chinese Medicine Formula Granule Engineering & Technology Innovate Center, Shijiazhuang, China.; Quality Evaluation & Standardization Hebei Province Engineering Research Center of Traditional Chinese Medicine, Shijiazhuang, China.
Wang X; Hebei University of Chinese Medicine, Shijiazhuang, China.; Hebei Traditional Chinese Medicine Formula Granule Engineering & Technology Innovate Center, Shijiazhuang, China.; Quality Evaluation & Standardization Hebei Province Engineering Research Center of Traditional Chinese Medicine, Shijiazhuang, China.; Pokaż więcej
Źródło:: PeerJ [PeerJ] 2023 Sep 11; Vol. 11, pp. e15948. Date of Electronic Publication: 2023 Sep 11 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ecdysterone*/pharmacology
Commelinaceae*
Molecular Docking Simulation ; Network Pharmacology ; Phosphatidylinositol 3-Kinases ; Hypoglycemic Agents/pharmacology

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Skocz do pozycji: 7.

Tytuł:: Mechanism of action of Huangbaichen Sanwei formulation in treating T2DM based on network pharmacology and molecular docking.
Autorzy:: Li C; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China.
Shen J; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China.
Jing X; College of pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Zhang K; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China.
Liu L; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China.
Wang Y; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China.
Zhang H; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China.
Sun J; Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China.; Pokaż więcej
Źródło:: Medicine [Medicine (Baltimore)] 2023 Nov 17; Vol. 102 (46), pp. e36146.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Type 2*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Humans ; Molecular Docking Simulation ; Network Pharmacology ; Protein Interaction Maps ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Medicine, Chinese Traditional

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Skocz do pozycji: 8.

Tytuł:: Network pharmacology and experimental validation methods to reveal the active compounds and hub targets of Curculigo orchioides Gaertn in rheumatoid arthritis.
Autorzy:: Liu X; Department of Pharmacy, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi Qizhi Road, Chongqing, 400021, China.
Huang M; Department of Pharmacy, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi Qizhi Road, Chongqing, 400021, China.
Wang L; Department of Pharmacy, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi Qizhi Road, Chongqing, 400021, China.
Li J; Department of Pharmacy, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi Qizhi Road, Chongqing, 400021, China.
Wu W; Department of Pharmacy, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi Qizhi Road, Chongqing, 400021, China. .
Wang Q; Department of Pharmacy, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi Qizhi Road, Chongqing, 400021, China. .; Pokaż więcej
Źródło:: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2023 Nov 13; Vol. 18 (1), pp. 861. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:: Journal Article
MeSH Terms:: Curculigo*
Arthritis, Rheumatoid*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Animals ; Rats ; Matrix Metalloproteinase 9 ; Network Pharmacology ; Cyclooxygenase 2 ; Molecular Docking Simulation ; Glucosides

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Skocz do pozycji: 9.

Tytuł:: Network Pharmacology Combined with Machine Learning to Reveal the Action Mechanism of Licochalcone Intervention in Liver Cancer.
Autorzy:: Guo F; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Science, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
Yang X; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Science, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
Hu C; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Science, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
Li W; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Science, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
Han W; Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Science, Jilin University, 2699 Qianjin Street, Changchun 130012, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 03; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:: Journal Article
MeSH Terms:: Chalcones*/pharmacology
Chalcones*/chemistry
Liver Neoplasms*/drug therapy
Humans ; Network Pharmacology ; Flavonoids ; NF-kappa B

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Skocz do pozycji: 10.

Tytuł:: Integrated network pharmacology to investigate the mechanism of Salvia miltiorrhiza Bunge in the treatment of myocardial infarction.
Autorzy:: Huang X; School of pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Zhang M; First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Song Y; Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Sun B; Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Lin L; Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Song X; School of pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Li C; Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.; Pokaż więcej
Źródło:: Journal of cellular and molecular medicine [J Cell Mol Med] 2023 Nov; Vol. 27 (22), pp. 3514-3525. Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:: Journal Article
MeSH Terms:: Salvia miltiorrhiza*
Myocardial Infarction*/drug therapy
Myocardial Infarction*/genetics
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Humans ; Network Pharmacology ; Reproducibility of Results ; Databases, Genetic ; Medicine, Chinese Traditional ; Molecular Docking Simulation

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Skocz do pozycji: 11.

Tytuł:: An integrated approach based on ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry, network pharmacology, and molecular docking to study the key effective compounds and mechanism of action of Platycodi Radix in the treatment of chronic obstructive pulmonary disease.
Autorzy:: Wang M; School of Pharmaceutical Sciences, Jilin University, Changchun, China.
Pei S; School of Pharmaceutical Sciences, Jilin University, Changchun, China.
Xie L; Chengdu Meishi International School, Chengdu, China.
Li H; School of Pharmaceutical Sciences, Jilin University, Changchun, China.
Tang S; School of Pharmaceutical Sciences, Jilin University, Changchun, China.
Li Y; School of Pharmaceutical Sciences, Jilin University, Changchun, China.
Chen Z; School of Pharmaceutical Sciences, Jilin University, Changchun, China.
Liu S; National Center of Mass Spectrometry, Changchun and Jilin Provincial Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China.
Liu Z; School of Pharmaceutical Sciences, Jilin University, Changchun, China.; Pokaż więcej
Źródło:: Journal of separation science [J Sep Sci] 2023 Nov; Vol. 46 (21), pp. e2300398. Date of Electronic Publication: 2023 Sep 08.
Typ publikacji:: Journal Article
MeSH Terms:: Pulmonary Disease, Chronic Obstructive*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Humans ; Molecular Docking Simulation ; Network Pharmacology ; Chromatography, Liquid ; Mass Spectrometry
SCR Organism:: Hygrophila, gastropods

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Skocz do pozycji: 12.

Tytuł:: Investigating the Underlying Mechanisms of Ardisia japonica Extract's Anti-Blood-Stasis Effect via Metabolomics and Network Pharmacology.
Autorzy:: He C; School of Pharmacy, Minzu University of China, Beijing 100081, China.; Faculty of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China.
Hao E; Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Guangxi University of Chinese Medicine, Nanning 530200, China.
Du C; Faculty of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China.
Wei W; Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Guangxi University of Chinese Medicine, Nanning 530200, China.
Wang X; Faculty of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China.
Liu T; School of Pharmacy, Minzu University of China, Beijing 100081, China.
Deng J; Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Guangxi University of Chinese Medicine, Nanning 530200, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Oct 27; Vol. 28 (21). Date of Electronic Publication: 2023 Oct 27.
Typ publikacji:: Journal Article
MeSH Terms:: Ardisia*
Drugs, Chinese Herbal*/pharmacology
Rats ; Animals ; Network Pharmacology ; Molecular Docking Simulation ; Phosphatidylinositol 3-Kinases ; Metabolomics/methods ; Inflammation/drug therapy

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Skocz do pozycji: 13.

Tytuł:: Network pharmacology and experimental verification of the potential mechanism of Er-Xian decoction in aplastic anemia.
Autorzy:: Ye M; Department of Hematology, The Affiliated Hospital of Panzhihua University, Panzhihua, China.
Liu G; Department of Pharmacy, The Affiliated Hospital of Panzhihua University, Panzhihua, China.
Yang Y; School of Basic Medicine, Panzhihua University, Panzhihua, China.
Yang H; Department of Clinical Laboratory, The Affiliated Hospital of Panzhihua University, Panzhihua, China.
Ren J; Department of Clinical Laboratory, The Affiliated Hospital of Panzhihua University, Panzhihua, China.
Chen W; Department of Pharmacy, The Affiliated Hospital of Panzhihua University, Panzhihua, China.
Gao Z; Department of Hematology, The Affiliated Hospital of Panzhihua University, Panzhihua, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Oct 13; Vol. 13 (1), pp. 17385. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anemia, Aplastic*/drug therapy
Berberine*
Drugs, Chinese Herbal*/pharmacology
Animals ; Mice ; Network Pharmacology ; Janus Kinases ; Luteolin/pharmacology ; Molecular Docking Simulation ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt ; STAT Transcription Factors ; Signal Transduction ; Class I Phosphatidylinositol 3-Kinases

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Skocz do pozycji: 14.

Tytuł:: Chemical profiling and mechanistic studies of Zhi-Shang-Feng granules against influenza virus by high-performance liquid chromatography coupled with Q exactive focus hybrid quadrupole orbitrap high-resolution mass spectrometry in combination with network pharmacology analysis.
Autorzy:: Xie YY; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, P. R. China.; Guangdong Research Center for Quality Engineering Technology of Traditional Chinese Medicine, Guangzhou, P. R. China.; Key Laboratory of Digitalized Quality Evaluation Technology of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, Guangzhou, P. R. China.
Luo JY; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, P. R. China.; Guangdong Research Center for Quality Engineering Technology of Traditional Chinese Medicine, Guangzhou, P. R. China.; Key Laboratory of Digitalized Quality Evaluation Technology of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, Guangzhou, P. R. China.
Hu H; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, P. R. China.; Guangdong Research Center for Quality Engineering Technology of Traditional Chinese Medicine, Guangzhou, P. R. China.; Key Laboratory of Digitalized Quality Evaluation Technology of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, Guangzhou, P. R. China.
Pan J; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, P. R. China.; Guangdong Research Center for Quality Engineering Technology of Traditional Chinese Medicine, Guangzhou, P. R. China.; Key Laboratory of Digitalized Quality Evaluation Technology of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, Guangzhou, P. R. China.
Jiang M; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, P. R. China.; Guangdong Research Center for Quality Engineering Technology of Traditional Chinese Medicine, Guangzhou, P. R. China.; Key Laboratory of Digitalized Quality Evaluation Technology of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, Guangzhou, P. R. China.
Wang SM; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, P. R. China.; Guangdong Research Center for Quality Engineering Technology of Traditional Chinese Medicine, Guangzhou, P. R. China.; Key Laboratory of Digitalized Quality Evaluation Technology of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, Guangzhou, P. R. China.; Pokaż więcej
Źródło:: Journal of separation science [J Sep Sci] 2023 Oct; Vol. 46 (20), pp. e2200839. Date of Electronic Publication: 2023 Aug 13.
Typ publikacji:: Journal Article
MeSH Terms:: Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/chemistry
Orthomyxoviridae*
Chromatography, High Pressure Liquid ; Network Pharmacology ; Mass Spectrometry/methods

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Skocz do pozycji: 15.

Tytuł:: Elucidating the mechanisms underlying the anti-hyperlipidemic effects of Laportea bulbifera using integrated serum metabolomics and network pharmacology.
Autorzy:: Shi Q; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Lin Y; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Huang L; Department of Pharmacy, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jin S; College of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Huang R; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Zhang L; College of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Song C; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Xu L; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Zhang S; Department of Pharmacy, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Pokaż więcej
Źródło:: Biomedical chromatography : BMC [Biomed Chromatogr] 2023 Oct; Vol. 37 (10), pp. e5707. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:: Journal Article
MeSH Terms:: Plants, Medicinal*
Drugs, Chinese Herbal*/pharmacology
Rats ; Animals ; Rats, Sprague-Dawley ; Network Pharmacology ; Metabolomics/methods

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Skocz do pozycji: 16.

Tytuł:: Combining network pharmacology and in vitro and in vivo experiments to study the mechanism of Keluoxin in the treatment of radiation nephropathy†.
Autorzy:: Deng L; Nephrology Department of The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, China, No. 4, North Section 4, Second Ring Road, Chengdu 610057, China.
Wang S; Nephrology Department of The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, China, No. 4, North Section 4, Second Ring Road, Chengdu 610057, China.
Leng X; Nephrology Department of The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, China, No. 4, North Section 4, Second Ring Road, Chengdu 610057, China.
Yao P; Nephrology Department of The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, China, No. 4, North Section 4, Second Ring Road, Chengdu 610057, China.
Li C; Physical Examination Center of General Hospital of Western Warzone, China, No. 270 Tianhui Road, Rongdu Avenue, Chengdu, Sichuan Province 610083, China.
Zheng Y; Nephrology Department of The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, China, No. 4, North Section 4, Second Ring Road, Chengdu 610057, China.; Pokaż więcej
Źródło:: Journal of radiation research [J Radiat Res] 2023 Sep 22; Vol. 64 (5), pp. 769-782.
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-6*
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Animals ; Mice ; Network Pharmacology ; Tumor Necrosis Factor-alpha ; Databases, Factual ; Disease Models, Animal

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Skocz do pozycji: 17.

Tytuł:: Mechanisms underlying the therapeutic effects of isoflavones isolated from chickpea sprouts in treating osteoporosis based on network pharmacology.
Autorzy:: Huang J; Clinical Medicine Institute, State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China; Department of Trauma Orthopaedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China; Key Laboratory of High Incidence Disease Research in Xinjiang(Xinjiang Medical University), Ministry of Education, Urumqi, 830011, Xinjiang, China; Xinjiang Clinical Research Centre for Orthopaedics, Urumqi, 830011, Xinjiang, China.
Wang X; Department of Trauma Orthopaedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China; Key Laboratory of High Incidence Disease Research in Xinjiang(Xinjiang Medical University), Ministry of Education, Urumqi, 830011, Xinjiang, China; Xinjiang Clinical Research Centre for Orthopaedics, Urumqi, 830011, Xinjiang, China.
Zheng J; Department of Joint Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China; Key Laboratory of High Incidence Disease Research in Xinjiang(Xinjiang Medical University), Ministry of Education, Urumqi, 830011, Xinjiang, China; Xinjiang Clinical Research Centre for Orthopaedics, Urumqi, 830011, Xinjiang, China.
Jia Q; Department of Trauma Orthopaedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China; Key Laboratory of High Incidence Disease Research in Xinjiang(Xinjiang Medical University), Ministry of Education, Urumqi, 830011, Xinjiang, China; Xinjiang Clinical Research Centre for Orthopaedics, Urumqi, 830011, Xinjiang, China.
Wang X; Department of Trauma Orthopaedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China; Key Laboratory of High Incidence Disease Research in Xinjiang(Xinjiang Medical University), Ministry of Education, Urumqi, 830011, Xinjiang, China; Xinjiang Clinical Research Centre for Orthopaedics, Urumqi, 830011, Xinjiang, China.
Xie Z; Department of Trauma Orthopaedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China; Key Laboratory of High Incidence Disease Research in Xinjiang(Xinjiang Medical University), Ministry of Education, Urumqi, 830011, Xinjiang, China; Xinjiang Clinical Research Centre for Orthopaedics, Urumqi, 830011, Xinjiang, China. Electronic address: .
Ma H; Clinical Medicine Institute, State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830011, Xinjiang, China; Key Laboratory of High Incidence Disease Research in Xinjiang(Xinjiang Medical University), Ministry of Education, Urumqi, 830011, Xinjiang, China; Xinjiang Clinical Research Centre for Orthopaedics, Urumqi, 830011, Xinjiang, China. Electronic address: .; Pokaż więcej
Źródło:: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Sep 03; Vol. 671, pp. 26-37. Date of Electronic Publication: 2023 May 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Isoflavones*/pharmacology
Isoflavones*/therapeutic use
Cicer*/chemistry
Cicer*/metabolism
Osteoporosis*/drug therapy
Osteoporosis*/prevention & control
Rats ; Animals ; Network Pharmacology ; Molecular Docking Simulation

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 18.

Tytuł:: Protective effects of Typhonii Rhizoma in rheumatoid arthritis rats revealed by integrated metabolomics and network pharmacology.
Autorzy:: Zhang X; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Wang B; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Chen S; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, China.; Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment and Chinese Medicine Development of Henan Province, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Fu Y; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, China.; Henan Lingrui Pharmaceutical Company, Xinyang, Henan, China.; Pokaż więcej
Źródło:: Biomedical chromatography : BMC [Biomed Chromatogr] 2023 Sep; Vol. 37 (9), pp. e5683. Date of Electronic Publication: 2023 May 24.
Typ publikacji:: Journal Article
MeSH Terms:: Arthritis, Experimental*/drug therapy
Arthritis, Experimental*/metabolism
Arthritis, Rheumatoid*/drug therapy
Arthritis, Rheumatoid*/metabolism
Drugs, Chinese Herbal*/pharmacology
Rats ; Animals ; Network Pharmacology ; Metabolomics/methods ; Inflammation/metabolism

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 19.

Tytuł:: Predicting the anti-inflammatory mechanism of Radix Astragali using network pharmacology and molecular docking.
Autorzy:: Ren J; College of Medicine, Tibet University, Lhasa, China.
Ding Y; College of Medicine, Tibet University, Lhasa, China.
Li S; College of Medicine, Tibet University, Lhasa, China.; School of Medicine, Chongqing University, Chongqing, China.
Lei M; Department of Science and Technology of Tibet Autonomous Region, Lhasa, China.; Pokaż więcej
Źródło:: Medicine [Medicine (Baltimore)] 2023 Sep 01; Vol. 102 (35), pp. e34945.
Typ publikacji:: Journal Article
MeSH Terms:: Network Pharmacology*
Kaempferols*/pharmacology
Humans ; Molecular Docking Simulation ; Interleukin-10 ; Toll-Like Receptor 4 ; Anti-Inflammatory Agents/pharmacology

Czasopismo naukowe

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Szczegóły

Skocz do pozycji: 20.

Tytuł:: The Anti-atherosclerosis Mechanism of Ziziphora clinopodioides Lam. Based On Network Pharmacology.
Autorzy:: Liu H; School of Chinese Pharmacy, Beijing University of Chinese Medicine, 102488, Beijing, China.; College of Traditional Chinese Medicine, Xinjiang Medical University, 830011, Urumqi, China.; Xinjiang Key Laboratory of Famous Prescription and Science of Formulas, 830011, Urumqi, China.
Zhang J; College of Traditional Chinese Medicine, Xinjiang Medical University, 830011, Urumqi, China.; Xinjiang Key Laboratory of Famous Prescription and Science of Formulas, 830011, Urumqi, China.
Yan X; School of Chinese Pharmacy, Beijing University of Chinese Medicine, 102488, Beijing, China.; College of Traditional Chinese Medicine, Xinjiang Medical University, 830011, Urumqi, China.; Xinjiang Key Laboratory of Famous Prescription and Science of Formulas, 830011, Urumqi, China.
An D; College of Traditional Chinese Medicine, Xinjiang Medical University, 830011, Urumqi, China. .; Xinjiang Key Laboratory of Famous Prescription and Science of Formulas, 830011, Urumqi, China. .
Lei H; School of Chinese Pharmacy, Beijing University of Chinese Medicine, 102488, Beijing, China. hm_.; Pokaż więcej
Źródło:: Cell biochemistry and biophysics [Cell Biochem Biophys] 2023 Sep; Vol. 81 (3), pp. 515-532. Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:: Journal Article
MeSH Terms:: Network Pharmacology*
Drugs, Chinese Herbal*
Proprotein Convertase 9 ; Molecular Docking Simulation ; Flavonoids/pharmacology

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