Temat: "Pharmacology" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Insights into the mechanisms underlying opioid use disorder and potential treatment strategies.
Autorzy:: Cao DN; Beijing Key Laboratory of Neuropsychopharmacology, State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Li F; Beijing Key Laboratory of Neuropsychopharmacology, State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Wu N; Beijing Key Laboratory of Neuropsychopharmacology, State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Li J; Beijing Key Laboratory of Neuropsychopharmacology, State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (7), pp. 862-878. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Opioid-Related Disorders*/drug therapy
Buprenorphine*/pharmacology
Buprenorphine*/therapeutic use
Humans ; Analgesics, Opioid/pharmacology ; Analgesics, Opioid/therapeutic use ; Methadone/pharmacology ; Methadone/therapeutic use ; Naltrexone/pharmacology ; Naltrexone/therapeutic use

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: The anomalous pharmacology of fentanyl.
Autorzy:: Kelly E; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Sutcliffe K; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Cavallo D; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Ramos-Gonzalez N; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Alhosan N; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Henderson G; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (7), pp. 797-812. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Fentanyl*/pharmacology
Drug Overdose*/drug therapy
Drug Overdose*/epidemiology
Humans ; Analgesics, Opioid/pharmacology ; Analgesics, Opioid/therapeutic use ; Narcotic Antagonists ; Naloxone/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: Fifty years with aspirin and platelets.
Autorzy:: Patrono C; Department of Pharmacology, Catholic University School of Medicine, Rome, Italy.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Jan; Vol. 180 (1), pp. 25-43. Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Aspirin*/pharmacology
Cyclooxygenase Inhibitors*/pharmacology
Blood Platelets ; Platelet Aggregation Inhibitors/pharmacology ; Cyclooxygenase 2/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: The flavonoid GL-V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells.
Autorzy:: Zhao J; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.
Bai D; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.
Qi L; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.
Cao W; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.
Du J; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.
Gu C; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.
Zhou C; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.
Gao Y; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.
Zhang L; Department of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Zhao Y; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.
Lu N; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (8), pp. 1072-1089. Date of Electronic Publication: 2022 Dec 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hepatic Stellate Cells*
Flavonoids*/pharmacology
Mice ; Animals ; Humans ; GATA4 Transcription Factor/metabolism ; GATA4 Transcription Factor/pharmacology ; Liver Cirrhosis/metabolism ; Liver/metabolism ; Fibrosis

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: A novel G protein-biased agonist at the μ opioid receptor induces substantial receptor desensitisation through G protein-coupled receptor kinase.
Autorzy:: Groom S; Department of Pharmacy and Pharmacology, University of Bath, Bath, UK.; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Blum NK; Institute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Conibear AE; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Disney A; Department of Pharmacy and Pharmacology, University of Bath, Bath, UK.
Hill R; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.; School of Life Sciences, University of Nottingham, Nottingham, UK.
Husbands SM; Department of Pharmacy and Pharmacology, University of Bath, Bath, UK.
Li Y; Department of Drug Discovery and Biomedical Sciences, University of South Carolina, Columbia, South Carolina, USA.
Toll L; Department of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA.
Kliewer A; Institute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Schulz S; Institute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Henderson G; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Kelly E; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Bailey CP; Department of Pharmacy and Pharmacology, University of Bath, Bath, UK.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Apr; Vol. 180 (7), pp. 943-957. Date of Electronic Publication: 2020 Dec 27.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Analgesics, Opioid*/pharmacology
Receptors, Opioid, mu*/metabolism
Rats ; Humans ; Animals ; GTP-Binding Proteins/metabolism ; Morphine/pharmacology ; Signal Transduction ; G-Protein-Coupled Receptor Kinases/metabolism ; Mammals/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe pathways.
Autorzy:: Liu Y; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, PR China.
Li H; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, PR China.
Luo Z; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, PR China.
Yu Y; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, PR China.
Yang J; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, PR China.
Zhang M; Department of Hematology, Union Hospital of Huazhong University of Science and Technology, Wuhan, Hubei, PR China.
Law BYK; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau SAR, PR China.
Huang Z; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, PR China.
Li W; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, PR China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Mar; Vol. 180 (6), pp. 701-720. Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antimalarials*/pharmacology
Antimalarials*/therapeutic use
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/metabolism
Leukemia, Myeloid, Acute*/pathology
Female ; Animals ; Mice ; Artesunate/pharmacology ; Reactive Oxygen Species/metabolism ; Mice, Inbred C57BL ; Apoptosis ; Cell Line, Tumor ; Receptors, Transferrin/therapeutic use

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Icariside II preconditioning evokes robust neuroprotection against ischaemic stroke, by targeting Nrf2 and the OXPHOS/NF-κB/ferroptosis pathway.
Autorzy:: Gao J; School of Pharmacy, Zunyi Medical University, Zunyi, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province, Zunyi Medical University, Zunyi, China.
Ma C; School of Pharmacy, Zunyi Medical University, Zunyi, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province, Zunyi Medical University, Zunyi, China.
Xia D; School of Pharmacy, Zunyi Medical University, Zunyi, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province, Zunyi Medical University, Zunyi, China.
Chen N; School of Pharmacy, Zunyi Medical University, Zunyi, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province, Zunyi Medical University, Zunyi, China.
Zhang J; School of Pharmacy, Zunyi Medical University, Zunyi, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province, Zunyi Medical University, Zunyi, China.
Xu F; Spemann Graduate School of Biology and Medicine (SGBM), Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Li F; School of Pharmacy, Zunyi Medical University, Zunyi, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province, Zunyi Medical University, Zunyi, China.
He Y; School of Pharmacy, Zunyi Medical University, Zunyi, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province, Zunyi Medical University, Zunyi, China.
Gong Q; School of Pharmacy, Zunyi Medical University, Zunyi, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.; Department of Pharmacology, Key Laboratory of Basic Pharmacology of Guizhou Province, Zunyi Medical University, Zunyi, China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Feb; Vol. 180 (3), pp. 308-329. Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain Ischemia*/drug therapy
Brain Ischemia*/prevention & control
Brain Ischemia*/metabolism
Ferroptosis*
Stroke*/drug therapy
Stroke*/prevention & control
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Ischemic Stroke*
Mice ; Animals ; NF-kappa B/metabolism ; Neuroprotection ; NF-E2-Related Factor 2/metabolism ; Signal Transduction ; Flavonoids/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Immunopathology of terminal complement activation and complement C5 blockade creating a pro-survival and organ-protective phenotype in trauma.
Autorzy:: Yang Z; US Army Institute of Surgical Research, JBSA-Fort Sam Houston, San Antonio, Texas, USA.
Nunn MA; Akari Therapeutics, London, UK.
Le TD; US Army Institute of Surgical Research, JBSA-Fort Sam Houston, San Antonio, Texas, USA.
Simovic MO; US Army Institute of Surgical Research, JBSA-Fort Sam Houston, San Antonio, Texas, USA.; The Geneva Foundation, Tacoma, Washington, USA.
Edsall PR; US Army Institute of Surgical Research, JBSA-Fort Sam Houston, San Antonio, Texas, USA.
Liu B; US Army Institute of Surgical Research, JBSA-Fort Sam Houston, San Antonio, Texas, USA.
Barr JL; US Army Institute of Surgical Research, JBSA-Fort Sam Houston, San Antonio, Texas, USA.
Lund BJ; 59th Medical Wing Operational Medicine, JBSA-Fort Sam Houston, San Antonio, Texas, USA.
Hill-Pryor CD; US Army Medical Research and Development Command, Fort Detrick, Maryland, USA.
Pusateri AE; Naval Medical Research Unit San Antonio, JBSA-Fort Sam Houston, San Antonio, Texas, USA.
Cancio LC; US Army Institute of Surgical Research, JBSA-Fort Sam Houston, San Antonio, Texas, USA.
Li Y; US Army Institute of Surgical Research, JBSA-Fort Sam Houston, San Antonio, Texas, USA.; The Geneva Foundation, Tacoma, Washington, USA.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Feb; Vol. 180 (4), pp. 422-440. Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Complement C5*/pharmacology
Shock, Hemorrhagic*/drug therapy
Rats ; Animals ; Complement Activation ; Immunologic Factors/pharmacology ; Phenotype

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: A plant-derived glucocorticoid receptor modulator with potency to attenuate the side effects of glucocorticoid therapy.
Autorzy:: Wang Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Gao J; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Yu Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Zhou L; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Wang M; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Xue W; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Liu B; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Collaborative Innovation Center of Biotherapy, Chengdu, China.
Wu X; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Wu X; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Gao H; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Shen Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Xu Q; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Jan; Vol. 180 (2), pp. 194-213. Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Receptors, Glucocorticoid*/metabolism
Glucocorticoids*/pharmacology
Mice ; Animals ; Dexamethasone/pharmacology ; Molecular Docking Simulation ; Anti-Inflammatory Agents/pharmacology ; Inflammation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Anti-inflammatory effects of cannabidiol against lipopolysaccharides in cardiac sodium channels.
Autorzy:: Fouda MA; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada.; Department of Pharmacology and Toxicology, Alexandria University, Alexandria, Egypt.
Fathy Mohamed Y; Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Microbiology and Immunology, Alexandria University, Alexandria, Egypt.
Fernandez R; Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Ruben PC; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Dec; Vol. 179 (24), pp. 5259-5272. Date of Electronic Publication: 2022 Aug 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cannabidiol*/pharmacology
Sepsis*
Sodium Channels*
Humans ; Anti-Inflammatory Agents/pharmacology ; Cytokines/metabolism ; Inflammation ; Interleukin-6 ; Lipopolysaccharides/pharmacology ; Toll-Like Receptor 4/metabolism ; Tumor Necrosis Factor-alpha

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Exploring pharmacological inhibition of G q/11 as an analgesic strategy.
Autorzy:: Marwari S; Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.
Kowalski C; Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.
Martemyanov KA; Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Dec; Vol. 179 (23), pp. 5196-5208. Date of Electronic Publication: 2022 Aug 15.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Analgesics*/pharmacology
Analgesics*/therapeutic use
Analgesics, Opioid*/pharmacology
Analgesics, Opioid*/therapeutic use
GTP-Binding Protein alpha Subunits, Gq-G11*/antagonists & inhibitors
Animals ; Mice ; Morphine/pharmacology ; Morphine/therapeutic use ; Pain/drug therapy ; Receptors, Opioid

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Pentoxifylline as a therapeutic option for pre-eclampsia: a study on its placental effects.
Autorzy:: Broekhuizen M; Division of Neonatology, Department of Paediatrics, Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Division of Experimental Cardiology, Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
de Vries R; Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Smits MAW; Laboratory Medical Immunology, Department of Immunology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Dik WA; Laboratory Medical Immunology, Department of Immunology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Schoenmakers S; Department of Obstetrics and Gynaecology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Koch BCP; Department of Pharmacy, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Merkus D; Division of Experimental Cardiology, Department of Cardiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Reiss IKM; Division of Neonatology, Department of Paediatrics, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Danser AHJ; Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Simons SHP; Division of Neonatology, Department of Paediatrics, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Hitzerd E; Division of Neonatology, Department of Paediatrics, Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Nov; Vol. 179 (22), pp. 5074-5088. Date of Electronic Publication: 2022 Aug 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Pentoxifylline*/metabolism
Pentoxifylline*/pharmacology
Pentoxifylline*/therapeutic use
Pre-Eclampsia*/drug therapy
Adenosine/pharmacology ; Anti-Inflammatory Agents/pharmacology ; Cyclic GMP/metabolism ; Female ; Humans ; Nitric Oxide Synthase/metabolism ; Phosphodiesterase Inhibitors/pharmacology ; Phosphodiesterase Inhibitors/therapeutic use ; Placenta/metabolism ; Pregnancy ; Purinergic P1 Receptor Antagonists/metabolism ; Purinergic P1 Receptor Antagonists/pharmacology ; Purinergic P1 Receptor Antagonists/therapeutic use ; Vasodilator Agents/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Statin activation of skeletal ryanodine receptors (RyR1) is a class effect but separable from HMG-CoA reductase inhibition.
Autorzy:: Lindsay C; Department of Pharmacology, University of Oxford, Oxford, UK.
Musgaard M; Structural Bioinformatics and Computational Biochemistry, Department of Biochemistry, University of Oxford, Oxford, UK.; OMass Therapeutics, Oxford, UK.
Russell AJ; Department of Pharmacology, University of Oxford, Oxford, UK.; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
Sitsapesan R; Department of Pharmacology, University of Oxford, Oxford, UK.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Nov; Vol. 179 (21), pp. 4941-4957. Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology
Muscular Diseases*/chemically induced
Muscular Diseases*/drug therapy
Acyl Coenzyme A ; Animals ; Mice ; Muscle, Skeletal ; Rabbits ; Ryanodine/pharmacology ; Ryanodine Receptor Calcium Release Channel ; Sheep ; Simvastatin/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes.
Autorzy:: Cruz-López EO; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
Ren L; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.; Department of Pharmacy, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China.
Uijl E; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.; Division of Nephrology and Transplantation, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
Clahsen-van Groningen MC; Department of Pathology, Erasmus MC, Rotterdam, The Netherlands.; Institute of Experimental Medicine and Systems Biology, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
van Veghel R; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
Garrelds IM; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
Domenig O; Attoquant Diagnostics, Vienna, Austria.
Poglitsch M; Attoquant Diagnostics, Vienna, Austria.
Zlatev I; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Rooney T; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Kasper A; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Nioi P; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Foster D; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Danser AHJ; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2023 Jan; Vol. 180 (1), pp. 80-93. Date of Electronic Publication: 2022 Oct 02.
Typ publikacji:: Journal Article
MeSH Terms:: Angiotensin II*/drug effects
Angiotensin II*/genetics
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Hypertension*/drug therapy
Kidney Diseases*/drug therapy
Kidney Diseases*/metabolism
Kidney Diseases*/prevention & control
RNA, Small Interfering*/metabolism
RNA, Small Interfering*/pharmacology
RNA, Small Interfering*/therapeutic use
Animals ; Humans ; Rats ; Albuminuria ; Blood Pressure/drug effects ; Blood Pressure/genetics ; Liver/metabolism ; Renin/metabolism ; Renin-Angiotensin System ; Valsartan/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Donepezil inhibits neuromuscular junctional acetylcholinesterase and enhances synaptic transmission and function in isolated skeletal muscle.
Autorzy:: Redman RR; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
Mackenzie H; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
Dissanayake KN; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.
Eddleston M; Pharmacology, Toxicology and Therapeutics, Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
Ribchester RR; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Dec; Vol. 179 (24), pp. 5273-5289. Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acetylcholinesterase*/metabolism
Acetylcholinesterase*/pharmacology
Neuromuscular Junction*/metabolism
Humans ; Mice ; Animals ; Donepezil/pharmacology ; Synaptic Transmission ; Muscle, Skeletal/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Chondroitin sulfate proteoglycan is a potential target of memantine to improve cognitive function via the promotion of adult neurogenesis.
Autorzy:: Maeda S; Department of Anatomy and Neuroscience, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yamada J; Department of Anatomy and Neuroscience, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Iinuma KM; Department of Anatomy and Neuroscience, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Nadanaka S; Department of Biochemistry, Kobe Pharmaceutical University, Kobe, Japan.
Kitagawa H; Department of Biochemistry, Kobe Pharmaceutical University, Kobe, Japan.
Jinno S; Department of Anatomy and Neuroscience, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Oct; Vol. 179 (20), pp. 4857-4877. Date of Electronic Publication: 2022 Jul 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chondroitin Sulfate Proteoglycans*/metabolism
Chondroitin Sulfate Proteoglycans*/pharmacology
Memantine*/pharmacology
Animals ; Cognition ; Mice ; Nerve Growth Factors/pharmacology ; Neurogenesis

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: Selective block of adenosine A 2A receptors prevents ischaemic-like effects induced by oxygen and glucose deprivation in rat medium spiny neurons.
Autorzy:: Coppi E; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Gibb AJ; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Oct; Vol. 179 (20), pp. 4844-4856. Date of Electronic Publication: 2022 Jul 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Glucose*/pharmacology
Oxygen*/metabolism
Adenosine/pharmacology ; Animals ; Glutamic Acid/pharmacology ; Ion Channels ; Ischemia ; Ligands ; Neurons ; Rats ; Rats, Wistar ; Receptor, Adenosine A2A/metabolism ; Tetrodotoxin

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: α and β catalytic subunits of cAMP-dependent protein kinase regulate formoterol-induced inflammatory gene expression changes in human bronchial epithelial cells.
Autorzy:: Hamed O; Airways Inflammation Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Joshi R; Airways Inflammation Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Mostafa MM; Airways Inflammation Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Giembycz MA; Airways Inflammation Research Group, Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Sep; Vol. 179 (18), pp. 4593-4614. Date of Electronic Publication: 2022 Jul 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Asthma*/drug therapy
Tumor Necrosis Factor-alpha*/metabolism
Tumor Necrosis Factor-alpha*/pharmacology
Adrenergic beta-2 Receptor Agonists/pharmacology ; Catalytic Domain ; Colforsin/pharmacology ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Epithelial Cells/metabolism ; Ethanolamines/metabolism ; Ethanolamines/pharmacology ; Formoterol Fumarate/pharmacology ; Gene Expression ; Humans ; beta-Arrestins/metabolism ; beta-Arrestins/pharmacology ; beta-Arrestins/therapeutic use

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: Measuring mania-like elevated mood through amphetamine-induced 50-kHz ultrasonic vocalizations in rats.
Autorzy:: Wöhr M; Faculty of Psychology and Educational Sciences, Research Unit Brain and Cognition, Laboratory of Biological Psychology, Social and Affective Neuroscience Research Group, KU Leuven, Leuven, Belgium.; Leuven Brain Institute, KU Leuven, Leuven, Belgium.; Faculty of Psychology, Experimental and Biological Psychology, Behavioral Neuroscience, Philipps-University of Marburg, Marburg, Germany.; Center for Mind, Brain and Behavior, Philipps-University of Marburg, Marburg, Germany.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Sep; Vol. 179 (17), pp. 4201-4219. Date of Electronic Publication: 2021 May 21.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Amphetamine*/pharmacology
Ultrasonics*
Animals ; Antimanic Agents/pharmacology ; Antimanic Agents/therapeutic use ; Dextroamphetamine/pharmacology ; Mania ; Rats ; Vocalization, Animal

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Limonin stabilises sirtuin 6 (SIRT6) by activating ubiquitin specific peptidase 10 (USP10) in cardiac hypertrophy.
Autorzy:: Liu LB; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Huang SH; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Qiu HL; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Cen XF; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Guo YY; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Li D; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Ma YL; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Xu M; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Tang QZ; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Sep; Vol. 179 (18), pp. 4516-4533. Date of Electronic Publication: 2022 Jul 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Limonins*/metabolism
Limonins*/pharmacology
Sirtuins*/metabolism
Animals ; Cardiomegaly/metabolism ; Cycloheximide/metabolism ; Cycloheximide/pharmacology ; Mice ; Myocytes, Cardiac ; Phenylephrine/pharmacology ; RNA, Small Interfering/pharmacology ; Rats ; Ubiquitin Thiolesterase/metabolism ; Ubiquitin-Specific Proteases/metabolism ; Ubiquitin-Specific Proteases/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Pharmacology"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Język

Rok publikacji