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Wyszukujesz frazę ""Phenotype"" wg kryterium: Temat


Tytuł:
Cell senescence, the senescence-associated secretory phenotype, and cancers.
Autorzy:
Langhi Prata LGP; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of America.
Tchkonia T; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of America.
Kirkland JL; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of America.; Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2023 Sep 21; Vol. 21 (9), pp. e3002326. Date of Electronic Publication: 2023 Sep 21 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Senescence-Associated Secretory Phenotype*
Neoplasms*/genetics
Humans ; Cellular Senescence/genetics ; Cell Differentiation ; Inflammation ; Phenotype
Czasopismo naukowe
Tytuł:
Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.
Autorzy:
Shrestha N; HCW Biologics Inc., Miramar, Florida, USA.
Chaturvedi P; HCW Biologics Inc., Miramar, Florida, USA.
Zhu X; HCW Biologics Inc., Miramar, Florida, USA.
Dee MJ; HCW Biologics Inc., Miramar, Florida, USA.
George V; HCW Biologics Inc., Miramar, Florida, USA.
Janney C; HCW Biologics Inc., Miramar, Florida, USA.
Egan JO; HCW Biologics Inc., Miramar, Florida, USA.
Liu B; HCW Biologics Inc., Miramar, Florida, USA.
Foster M; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Marsala L; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Wong P; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Cubitt CC; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Foltz JA; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Tran J; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Schappe T; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Hsiao K; Department of Pharmaceutical Sciences, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Leclerc GM; HCW Biologics Inc., Miramar, Florida, USA.
You L; HCW Biologics Inc., Miramar, Florida, USA.
Echeverri C; HCW Biologics Inc., Miramar, Florida, USA.
Spanoudis C; HCW Biologics Inc., Miramar, Florida, USA.
Carvalho A; HCW Biologics Inc., Miramar, Florida, USA.
Kanakaraj L; HCW Biologics Inc., Miramar, Florida, USA.
Gilkes C; HCW Biologics Inc., Miramar, Florida, USA.
Encalada N; HCW Biologics Inc., Miramar, Florida, USA.
Kong L; HCW Biologics Inc., Miramar, Florida, USA.
Wang M; HCW Biologics Inc., Miramar, Florida, USA.
Fang B; HCW Biologics Inc., Miramar, Florida, USA.
Wang Z; HCW Biologics Inc., Miramar, Florida, USA.
Jiao JA; HCW Biologics Inc., Miramar, Florida, USA.
Muniz GJ; HCW Biologics Inc., Miramar, Florida, USA.
Jeng EK; HCW Biologics Inc., Miramar, Florida, USA.
Valdivieso N; HCW Biologics Inc., Miramar, Florida, USA.
Li L; HCW Biologics Inc., Miramar, Florida, USA.
Deth R; Department of Pharmaceutical Sciences, Nova Southeastern University, Fort Lauderdale, Florida, USA.
Berrien-Elliott MM; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Fehniger TA; Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Rhode PR; HCW Biologics Inc., Miramar, Florida, USA.
Wong HC; HCW Biologics Inc., Miramar, Florida, USA.
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Źródło:
Aging cell [Aging Cell] 2023 May; Vol. 22 (5), pp. e13806. Date of Electronic Publication: 2023 Mar 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Senescence-Associated Secretory Phenotype*
Cellular Senescence*/genetics
Mice ; Animals ; Aging ; Inflammation ; Immunotherapy ; Phenotype
Czasopismo naukowe
Tytuł:
Long-Term Cultured Human Glioblastoma Multiforme Cells Demonstrate Increased Radiosensitivity and Senescence-Associated Secretory Phenotype in Response to Irradiation.
Autorzy:
Alhaddad L; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.; Department of Environmental Sciences, Faculty of Sciences, Damascus University, Damascus P.O. Box 30621, Syria.
Nofal Z; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.
Pustovalova M; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.; State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC-FMBC), 123098 Moscow, Russia.
Osipov AN; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.; State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC-FMBC), 123098 Moscow, Russia.; N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, 119991 Moscow, Russia.
Leonov S; School of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia.; Institute of Cell Biophysics, Russian Academy of Sciences, 142290 Pushchino, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 19; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Senescence-Associated Secretory Phenotype*
Glioblastoma*/metabolism
Humans ; Cellular Senescence ; Cell Line ; Cells, Cultured ; Radiation Tolerance ; Phenotype
Czasopismo naukowe
Tytuł:
The variant senescence-associated secretory phenotype induced by centrosome amplification constitutes a pathway that activates hypoxia-inducible factor-1α.
Autorzy:
Wu SK; Department of Cell Biology, Harvard Medical School, Massachusetts, Boston, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Massachusetts, Boston, USA.
Ariffin J; Department of Surgery, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Massachusetts, Boston, USA.
Tay SC; Mechanobiology Institute, National University of Singapore, Singapore.
Picone R; Department of Cell Biology, Harvard Medical School, Massachusetts, Boston, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Massachusetts, Boston, USA.
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Źródło:
Aging cell [Aging Cell] 2023 Mar; Vol. 22 (3), pp. e13766. Date of Electronic Publication: 2023 Jan 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Senescence-Associated Secretory Phenotype*
Neoplasms*/pathology
Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Cellular Senescence/genetics ; Centrosome/metabolism ; Centrosome/pathology ; Carcinogenesis ; Phenotype ; NF-kappa B/metabolism
Czasopismo naukowe
Tytuł:
Early life jumping traits: Are they good proxies for success in show jumping competitions in Belgian warmblood horses?
Autorzy:
Chapard L; Department of Biosystems, Center for Animal Breeding and Genetics, KU Leuven, Leuven, Belgium.
Meyermans R; Department of Biosystems, Center for Animal Breeding and Genetics, KU Leuven, Leuven, Belgium.
Gorssen W; Department of Biosystems, Center for Animal Breeding and Genetics, KU Leuven, Leuven, Belgium.
Hooyberghs K; Department of Biosystems, Center for Animal Breeding and Genetics, KU Leuven, Leuven, Belgium.
Meurrens I; Belgian Warmblood Horses, Heverlee, Belgium.
De Smet S; Department of Animal Sciences and Aquatic Ecology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Buys N; Department of Biosystems, Center for Animal Breeding and Genetics, KU Leuven, Leuven, Belgium.
Janssens S; Department of Biosystems, Center for Animal Breeding and Genetics, KU Leuven, Leuven, Belgium.
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Źródło:
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie [J Anim Breed Genet] 2024 Mar; Vol. 141 (2), pp. 138-152. Date of Electronic Publication: 2023 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Phenotype*
Horses/genetics ; Animals ; Belgium
Czasopismo naukowe
Tytuł:
Crop-GPA: an integrated platform of crop gene-phenotype associations.
Autorzy:
Gao Y; School of Information and Artificial Intelligence, Anhui Beidou Precision Agriculture Information Engineering Research Center, Anhui Agricultural University, Hefei, Anhui, 230036, China.
Zhou Q; School of Information and Artificial Intelligence, Anhui Beidou Precision Agriculture Information Engineering Research Center, Anhui Agricultural University, Hefei, Anhui, 230036, China.
Luo J; School of Information and Artificial Intelligence, Anhui Beidou Precision Agriculture Information Engineering Research Center, Anhui Agricultural University, Hefei, Anhui, 230036, China.
Xia C; School of Information and Artificial Intelligence, Anhui Beidou Precision Agriculture Information Engineering Research Center, Anhui Agricultural University, Hefei, Anhui, 230036, China.
Zhang Y; School of Information and Artificial Intelligence, Anhui Beidou Precision Agriculture Information Engineering Research Center, Anhui Agricultural University, Hefei, Anhui, 230036, China. .
Yue Z; School of Information and Artificial Intelligence, Anhui Beidou Precision Agriculture Information Engineering Research Center, Anhui Agricultural University, Hefei, Anhui, 230036, China. .
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Źródło:
NPJ systems biology and applications [NPJ Syst Biol Appl] 2024 Feb 12; Vol. 10 (1), pp. 15. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:
Journal Article
MeSH Terms:
Phenotype*
Crops, Agricultural/genetics ; Genes, Plant
Czasopismo naukowe
Tytuł:
Development of a Low-Cost Distributed Computing Pipeline for High-Throughput Cotton Phenotyping.
Autorzy:
Thesma V; School of Electrical and Computer Engineering, University of Georgia, Athens, GA 30602, USA.
Rains GC; Department of Entomology, University of Georgia Tifton Campus, Tifton, GA 31793, USA.
Mohammadpour Velni J; Department of Mechanical Engineering, Clemson University, Clemson, SC 29634, USA.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2024 Feb 02; Vol. 24 (3). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Gossypium*
Phenotype*
Humans ; Electronic Data Processing
Czasopismo naukowe
Tytuł:
The Born in Guangzhou Cohort Study enables generational genetic discoveries.
Autorzy:
Huang S; Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Liu S; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Huang M; Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
He JR; Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.; Provincial Clinical Research Center for Child Health, Guangzhou, China.; Department of Obstetrics and Gynecology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Wang C; Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Wang T; Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, China.; University of the Chinese Academy of Sciences, Beijing, China.
Feng X; Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, China.; University of the Chinese Academy of Sciences, Beijing, China.
Kuang Y; Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.; Provincial Clinical Research Center for Child Health, Guangzhou, China.
Lu J; Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.; Provincial Clinical Research Center for Child Health, Guangzhou, China.
Gu Y; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, China.
Xia X; Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.; Department of Women's Health, Provincial Key Clinical Specialty of Woman and Child Health, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Lin S; Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.; Department of Women's Health, Provincial Key Clinical Specialty of Woman and Child Health, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Zhou W; Division of Neonatology and Center for Newborn Care, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Fu Q; Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, China.; University of the Chinese Academy of Sciences, Beijing, China.
Xia H; Provincial Clinical Research Center for Child Health, Guangzhou, China. .; Provincial Key Laboratory of Research in Structure Birth Defect Disease, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. .; Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. .
Qiu X; Division of Birth Cohort Study, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. .; Provincial Clinical Research Center for Child Health, Guangzhou, China. .; Department of Women's Health, Provincial Key Clinical Specialty of Woman and Child Health, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. .
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Corporate Authors:
Born in Guangzhou Cohort Study (BIGCS) Group
Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (7999), pp. 565-573. Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Cohort Studies*
Gene-Environment Interaction*
Phenotype*
Prenatal Exposure Delayed Effects*
Genome, Human*/genetics
Genetic Variation*/genetics
Adult ; Female ; Humans ; Infant ; Infant, Newborn ; Bile Acids and Salts/metabolism ; China/ethnology ; Cordocentesis ; Fetus/embryology ; Gestational Weight Gain ; Lipids/blood ; Maternal Exposure ; Parturition ; Prospective Studies
Czasopismo naukowe
Tytuł:
East Asian and Southern European craniofacial class III phenotype: two sides of the same coin?
Autorzy:
Dehesa-Santos A; School of Dentistry, Complutense University of Madrid, Pza. Ramón y Cajal, S/N. Ciudad Universitaria, 28040, Madrid, Spain.
Park JA; Department of Orthodontics, Seoul National University School of Dentistry, 101 Daehak-Ro, Jongno-Gu, 03080, Seoul, South Korea.
Lee SJ; Department of Orthodontics, Seoul National University School of Dentistry, 101 Daehak-Ro, Jongno-Gu, 03080, Seoul, South Korea.
Iglesias-Linares A; School of Dentistry, Complutense University of Madrid, Pza. Ramón y Cajal, S/N. Ciudad Universitaria, 28040, Madrid, Spain. .; Craniofacial Biology and Orthodontics Research Group, School of Dentistry, BIOCRAN, Complutense University of Madrid, Pza. Ramón y Cajal, S/N. Ciudad Universitaria, 28040, Madrid, Spain. .
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Źródło:
Clinical oral investigations [Clin Oral Investig] 2024 Jan 09; Vol. 28 (1), pp. 84. Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
East Asian People*
Phenotype*
Skull*/anatomy & histology
Humans ; Male ; Cross-Sectional Studies ; Ethnicity
Czasopismo naukowe
Tytuł:
On the nature of evolutionary explanations: a critical appraisal of Walter Bock's approach with a new revised proposal.
Autorzy:
de Santis MD; Departamento de Entomologia, Museu Nacional, UFRJ, Rio de Janeiro, RJ, Brazil. .; Museum Koenig Bonn, Leibniz-Institut zur Analyse des Bioaffiliationersitatswandels, Adenauerallee 127, 53113, Bonn, Germany. .
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Źródło:
History and philosophy of the life sciences [Hist Philos Life Sci] 2024 Jan 08; Vol. 46 (1), pp. 3. Date of Electronic Publication: 2024 Jan 08.
Typ publikacji:
Journal Article
MeSH Terms:
Phenotype*
Biological Evolution*
Czasopismo naukowe
Tytuł:
The Monarch Initiative in 2024: an analytic platform integrating phenotypes, genes and diseases across species.
Autorzy:
Putman TE; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Schaper K; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Matentzoglu N; Independent Consultant, Semanticly, Athens, Greece.
Rubinetti VP; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Alquaddoomi FS; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Cox C; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Caufield JH; Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Elsarboukh G; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Gehrke S; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Hegde H; Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Reese JT; Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Braun I; Data Collaboration Center, Critical Path Institute, Tucson, AZ 85718, USA.
Bruskiewich RM; STAR Informatics, Delphinai Corporation, Sooke, BC V9Z 0M3, Canada.
Cappelletti L; Biology, University of Fribourg, Fribourg, Switzerland.
Carbon S; Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Caron AR; European Bioinformatics Institute (EMBL-EBI), Hinxton CB10 1SD, UK.
Chan LE; College of Public Health and Human Sciences, Oregon State University, Corvallis, OR 97331, USA.
Chute CG; Schools of Medicine, Public Health, and Nursing, Johns Hopkins University, Baltimore, MD 21205, USA.
Cortes KG; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
De Souza V; European Bioinformatics Institute (EMBL-EBI), Hinxton CB10 1SD, UK.
Fontana T; Dipartimento di Informatica, Università degli Studi di Milano Statale, Milano, Italy.
Harris NL; Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Hartley EL; Data Collaboration Center, Critical Path Institute, Tucson, AZ 85718, USA.
Hurwitz E; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Jacobsen JOB; William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.
Krishnamurthy M; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Laraway BJ; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
McLaughlin JA; European Bioinformatics Institute (EMBL-EBI), Hinxton CB10 1SD, UK.
McMurry JA; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Moxon SAT; Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Mullen KR; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
O'Neil ST; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Shefchek KA; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Stefancsik R; European Bioinformatics Institute (EMBL-EBI), Hinxton CB10 1SD, UK.
Toro S; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Vasilevsky NA; Data Collaboration Center, Critical Path Institute, Tucson, AZ 85718, USA.
Walls RL; Data Collaboration Center, Critical Path Institute, Tucson, AZ 85718, USA.
Whetzel PL; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Osumi-Sutherland D; European Bioinformatics Institute (EMBL-EBI), Hinxton CB10 1SD, UK.
Smedley D; William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.
Robinson PN; The Jackson Laboratory for Genomic Medicine, Farmington, CT 6032, USA.
Mungall CJ; Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Haendel MA; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Munoz-Torres MC; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jan 05; Vol. 52 (D1), pp. D938-D949.
Typ publikacji:
Journal Article
MeSH Terms:
Phenotype*
Databases, Factual*/standards
Genes*/genetics
Disease*/genetics
Humans ; Internet ; Software
Czasopismo naukowe
Tytuł:
CropGS-Hub: a comprehensive database of genotype and phenotype resources for genomic prediction in major crops.
Autorzy:
Chen J; Shanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources, College of Life Sciences, Shanghai Normal University, Shanghai, China.
Tan C; State Key Laboratory of Agricultural Genomics, Key Laboratory of Genomics, Ministry of Agriculture, BGI Research, Shenzhen 518083, China.; BGI Research, Wuhan 430074, China.
Zhu M; Shanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources, College of Life Sciences, Shanghai Normal University, Shanghai, China.
Zhang C; State Key Laboratory of Agricultural Genomics, Key Laboratory of Genomics, Ministry of Agriculture, BGI Research, Shenzhen 518083, China.; BGI Bioverse, Shenzhen 518083, China.
Wang Z; Shanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources, College of Life Sciences, Shanghai Normal University, Shanghai, China.
Ni X; State Key Laboratory of Agricultural Genomics, Key Laboratory of Genomics, Ministry of Agriculture, BGI Research, Shenzhen 518083, China.; BGI Bioverse, Shenzhen 518083, China.
Liu Y; Shanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources, College of Life Sciences, Shanghai Normal University, Shanghai, China.
Wei T; State Key Laboratory of Agricultural Genomics, Key Laboratory of Genomics, Ministry of Agriculture, BGI Research, Shenzhen 518083, China.; BGI Research, Wuhan 430074, China.
Wei X; China National GeneBank, BGI, Shenzhen 518120, China.
Fang X; State Key Laboratory of Agricultural Genomics, Key Laboratory of Genomics, Ministry of Agriculture, BGI Research, Shenzhen 518083, China.; BGI Research, Sanya 572025, China.
Xu Y; Agricultural College, Yangzhou University, Yangzhou 225009, China.
Huang X; Shanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources, College of Life Sciences, Shanghai Normal University, Shanghai, China.
Qiu J; Shanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources, College of Life Sciences, Shanghai Normal University, Shanghai, China.
Liu H; State Key Laboratory of Agricultural Genomics, Key Laboratory of Genomics, Ministry of Agriculture, BGI Research, Shenzhen 518083, China.; BGI Bioverse, Shenzhen 518083, China.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jan 05; Vol. 52 (D1), pp. D1519-D1529.
Typ publikacji:
Journal Article
MeSH Terms:
Crops, Agricultural*/genetics
Genomics*
Genotype*
Phenotype*
Databases, Genetic*
Genome ; Genome-Wide Association Study ; Polymorphism, Single Nucleotide ; Internet
Czasopismo naukowe
Tytuł:
Branched-Chain Amino Acid Accumulation Fuels the Senescence-Associated Secretory Phenotype.
Autorzy:
Liang Y; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Pan C; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Yin T; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Wang L; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, 200031, China.
Gao X; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, USA.
Wang E; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Quang H; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, USA.
Huang; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.; School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China.
Tan L; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Xiang K; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Wang Y; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Alexander PB; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Li QJ; Department of Immunology, Duke University Medical Center, Durham, NC, 27710, USA.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.
Yao TP; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Zhang Z; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Wang XF; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
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Źródło:
Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Jan; Vol. 11 (2), pp. e2303489. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Senescence-Associated Secretory Phenotype*
Amino Acids, Branched-Chain*/metabolism
Animals ; Mice ; Leucine/metabolism ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Energy Metabolism ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
A spectrum of recessiveness among Mendelian disease variants in UK Biobank.
Autorzy:
Barton AR; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Bioinformatics and Integrative Genomics Program, Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: .
Hujoel MLA; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Mukamel RE; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Sherman MA; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Loh PR; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: .
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Źródło:
American journal of human genetics [Am J Hum Genet] 2022 Jul 07; Vol. 109 (7), pp. 1298-1307. Date of Electronic Publication: 2022 May 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Antley-Bixler Syndrome Phenotype*/genetics
Cystic Fibrosis*/genetics
Lung Diseases, Interstitial*/genetics
Alleles ; Databases, Factual ; Genetic Predisposition to Disease ; Humans ; Muscular Atrophy, Spinal/genetics ; Penetrance ; Phenotype ; United Kingdom
Czasopismo naukowe
Tytuł:
A 14-bp deletion in bovine EPAS1 gene is associated with carcass traits.
Autorzy:
Jiang E; Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Wang H; Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Li X; Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Bi Y; Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Mao C; Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Jiang F; Institute of Animal Science and Veterinary, Shandong Academy of Agriculture Science, Jinan, Shandong, China.
Song E; Institute of Animal Science and Veterinary, Shandong Academy of Agriculture Science, Jinan, Shandong, China.
Lan X; Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
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Źródło:
Animal biotechnology [Anim Biotechnol] 2023 Dec; Vol. 34 (9), pp. 4553-4558. Date of Electronic Publication: 2023 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Phenotype*
Female ; Cattle/genetics ; Animals ; Genotype
Czasopismo naukowe
Tytuł:
Single-cell, whole-embryo phenotyping of mammalian developmental disorders.
Autorzy:
Huang X; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA.
Henck J; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck & Kiel University, Lübeck, Germany.; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Qiu C; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Sreenivasan VKA; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck & Kiel University, Lübeck, Germany.
Balachandran S; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck & Kiel University, Lübeck, Germany.
Amarie OV; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Hrabě de Angelis M; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.; Chair of Experimental Genetics, TUM School of Life Sciences, Technische Universität München, Freising, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.
Behncke RY; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Chan WL; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Despang A; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Dickel DE; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Duran M; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Feuchtinger A; Core Facility Pathology & Tissue Analytics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Fuchs H; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Gailus-Durner V; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Haag N; Institute for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Hägerling R; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Hansmeier N; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Hennig F; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Marshall C; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA.
Rajderkar S; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Ringel A; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.
Robson M; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Saunders LM; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
da Silva-Buttkus P; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Spielmann N; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Srivatsan SR; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Ulferts S; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Wittler L; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Zhu Y; German Center for Diabetes Research (DZD), Neuherberg, Germany.
Kalscheuer VM; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Ibrahim DM; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Kurth I; Institute for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Kornak U; Institute of Human Genetics, University Medical Center Göttingen, Göttingen, Germany.
Visel A; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Pennacchio LA; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Beier DR; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA.; Center for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA, USA.; Department of Pediatrics, University of Washington, Seattle, WA, USA.
Trapnell C; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA.; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA.
Cao J; Laboratory of Single-Cell Genomics and Population Dynamics, The Rockefeller University, New York, NY, USA. .
Shendure J; Department of Genome Sciences, University of Washington, Seattle, WA, USA. .; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA. .; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA. .; Howard Hughes Medical Institute, Seattle, WA, USA. .
Spielmann M; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck & Kiel University, Lübeck, Germany. .; Max Planck Institute for Molecular Genetics, Berlin, Germany. .; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, Lübeck, Germany. .
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Źródło:
Nature [Nature] 2023 Nov; Vol. 623 (7988), pp. 772-781. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Developmental Disabilities*/genetics
Developmental Disabilities*/pathology
Embryo, Mammalian*/metabolism
Embryo, Mammalian*/pathology
Mutation*
Phenotype*
Single-Cell Gene Expression Analysis*
Animals ; Mice ; Cell Nucleus/genetics ; Gain of Function Mutation ; Genotype ; Loss of Function Mutation ; Models, Genetic ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
A novel approach for predicting upstream regulators (PURE) that affect gene expression.
Autorzy:
Nguyen TM; Department of Computer Science, Wayne State University, Detroit, 48202, USA.
Craig DB; Department of Computer Science, Wayne State University, Detroit, 48202, USA.; Department of Oncology, School of Medicine, Wayne State University, Detroit, MI, 48201, USA.
Tran D; Department of Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Nguyen T; Department of Computer Science and Software Engineering, Auburn University, Auburn, 36849, USA.
Draghici S; Department of Computer Science, Wayne State University, Detroit, 48202, USA. .; Advaita Bioinformatics, Ann Arbor, MI, 48105, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 30; Vol. 13 (1), pp. 18571. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Phenotype*
Animals ; Humans ; Mice ; Rats ; Gene Expression
Czasopismo naukowe
Tytuł:
New insights on Celtic migration in Hungary and Italy through the analysis of non-metric dental traits.
Autorzy:
Piccirilli E; Department of Cultural Heritage, University of Bologna, Ravenna, Italy.
Sorrentino R; Department of Biological, Geological and Environmental Sciences-BiGeA, University of Bologna, Bologna, Italy.
Lugli F; Department of Cultural Heritage, University of Bologna, Ravenna, Italy.; Department of Chemical and Geological Science, University of Modena and Reggio Emilia, Modena, Italy.
Bortolini E; Department of Cultural Heritage, University of Bologna, Ravenna, Italy.; Department of Archaeology and Anthropology, IMF-CSIC (Spanish National Research Centre), Barcelona, Spain.
Silvestrini S; Department of Cultural Heritage, University of Bologna, Ravenna, Italy.
Cavazzuti C; Department of History and Cultures, University of Bologna, Bologna, Italy.
Conti S; Department of Cultural Heritage, University of Bologna, Ravenna, Italy.
Czifra S; National Institute of Archaeology, Hungarian National Museum, Budapest, Hungary.
Gyenesei K; Department of Biological Anthropology, Faculty of Science, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Köhler K; Hungarian Natural History Museum, Department of Anthropology, Budapest, Hungary.
Tankó K; ELKH-ELTE Interdisciplinary Archaeological Research Group, Eötvös Loránd University, Budapest, Hungary.
Vazzana A; Department of Cultural Heritage, University of Bologna, Ravenna, Italy.
Jerem E; Hungarian Natural History Museum, Department of Anthropology, Budapest, Hungary.
Cipriani A; Department of Chemical and Geological Science, University of Modena and Reggio Emilia, Modena, Italy.; Lamont-Doherty Earth Observatory of Columbia University, Palisades, NY, United States of America.
Gottarelli A; Department of History and Cultures, University of Bologna, Bologna, Italy.
Belcastro MG; Department of Biological, Geological and Environmental Sciences-BiGeA, University of Bologna, Bologna, Italy.
Hajdu T; Department of Biological Anthropology, Faculty of Science, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Benazzi S; Department of Cultural Heritage, University of Bologna, Ravenna, Italy.
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Źródło:
PloS one [PLoS One] 2023 Oct 18; Vol. 18 (10), pp. e0293090. Date of Electronic Publication: 2023 Oct 18 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Phenotype*
Humans ; Hungary ; Italy ; Europe ; Austria
Czasopismo naukowe
Tytuł:
Large-scale plasma proteomics comparisons through genetics and disease associations.
Autorzy:
Eldjarn GH; deCODE Genetics/Amgen, Reykjavik, Iceland.
Ferkingstad E; deCODE Genetics/Amgen, Reykjavik, Iceland.
Lund SH; deCODE Genetics/Amgen, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Helgason H; deCODE Genetics/Amgen, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Magnusson OT; deCODE Genetics/Amgen, Reykjavik, Iceland.
Gunnarsdottir K; deCODE Genetics/Amgen, Reykjavik, Iceland.
Olafsdottir TA; deCODE Genetics/Amgen, Reykjavik, Iceland.
Halldorsson BV; deCODE Genetics/Amgen, Reykjavik, Iceland.; School of Technology, Reykjavik University, Reykjavik, Iceland.
Olason PI; deCODE Genetics/Amgen, Reykjavik, Iceland.
Zink F; deCODE Genetics/Amgen, Reykjavik, Iceland.
Gudjonsson SA; deCODE Genetics/Amgen, Reykjavik, Iceland.
Sveinbjornsson G; deCODE Genetics/Amgen, Reykjavik, Iceland.
Magnusson MI; deCODE Genetics/Amgen, Reykjavik, Iceland.
Helgason A; deCODE Genetics/Amgen, Reykjavik, Iceland.; Department of Anthropology, University of Iceland, Reykjavik, Iceland.
Oddsson A; deCODE Genetics/Amgen, Reykjavik, Iceland.
Halldorsson GH; deCODE Genetics/Amgen, Reykjavik, Iceland.
Magnusson MK; deCODE Genetics/Amgen, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Saevarsdottir S; deCODE Genetics/Amgen, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Eiriksdottir T; deCODE Genetics/Amgen, Reykjavik, Iceland.
Masson G; deCODE Genetics/Amgen, Reykjavik, Iceland.
Stefansson H; deCODE Genetics/Amgen, Reykjavik, Iceland.
Jonsdottir I; deCODE Genetics/Amgen, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Holm H; deCODE Genetics/Amgen, Reykjavik, Iceland.
Rafnar T; deCODE Genetics/Amgen, Reykjavik, Iceland.
Melsted P; deCODE Genetics/Amgen, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Saemundsdottir J; deCODE Genetics/Amgen, Reykjavik, Iceland.
Norddahl GL; deCODE Genetics/Amgen, Reykjavik, Iceland.
Thorleifsson G; deCODE Genetics/Amgen, Reykjavik, Iceland.
Ulfarsson MO; deCODE Genetics/Amgen, Reykjavik, Iceland.; Faculty of Electrical and Computer Engineering, University of Iceland, Reykjavik, Iceland.
Gudbjartsson DF; deCODE Genetics/Amgen, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Thorsteinsdottir U; deCODE Genetics/Amgen, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Sulem P; deCODE Genetics/Amgen, Reykjavik, Iceland. .
Stefansson K; deCODE Genetics/Amgen, Reykjavik, Iceland. .; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. .
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Źródło:
Nature [Nature] 2023 Oct; Vol. 622 (7982), pp. 348-358. Date of Electronic Publication: 2023 Oct 04.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Blood Proteins*/analysis
Blood Proteins*/genetics
Disease Susceptibility*
Genomics*
Genotype*
Phenotype*
Proteomics*/methods
Humans ; Africa/ethnology ; Asia, Southern/ethnology ; Biological Specimen Banks ; Datasets as Topic ; Genome, Human/genetics ; Iceland/ethnology ; Ireland/ethnology ; Plasma/chemistry ; Proteome/analysis ; Proteome/genetics ; Quantitative Trait Loci ; United Kingdom
Czasopismo naukowe
Tytuł:
Aging-related decrease of histone methyltransferase SUV39H1 in adipose-derived stem cells enhanced SASP.
Autorzy:
Li R; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China.
Teng Y; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China.
Guo Y; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China.
Ren J; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China.
Li R; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China.
Luo H; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China.
Chen D; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China.
Feng Z; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China.
Fu Z; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China.
Zou X; Guangdong Provincial Key Laboratory of Orthopaedics and Traumatology, Department of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Wang W; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China. Electronic address: .
Zhou C; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China. Electronic address: .
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Źródło:
Mechanisms of ageing and development [Mech Ageing Dev] 2023 Oct; Vol. 215, pp. 111868. Date of Electronic Publication: 2023 Sep 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epigenesis, Genetic*
Histones*/metabolism
Senescence-Associated Secretory Phenotype*/genetics
Animals ; Mice ; Aging ; Cellular Senescence ; Histone Methyltransferases/metabolism ; Mice, Inbred C57BL ; Stem Cells/metabolism
Czasopismo naukowe

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