Autor: "Phillips AJ" - OpacWWW

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Tytuł:: Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Autorzy:: Colegio OR; 1] Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA [2] Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06520-8059, USA [3] Yale-New Haven Transplantation Center, Yale University School of Medicine, New Haven, Connecticut 06519-1369, USA [4] Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520-8028, USA.
Chu NQ; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA.
Szabo AL; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA.
Chu T; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA.
Rhebergen AM; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA.
Jairam V; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA.
Cyrus N; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA.
Brokowski CE; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA.
Eisenbarth SC; 1] Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA [2] Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8035, USA.
Phillips GM; Department of Chemistry, Yale University School of Medicine, New Haven, Connecticut 06520-8107, USA.
Cline GW; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8020, USA.
Phillips AJ; Department of Chemistry, Yale University School of Medicine, New Haven, Connecticut 06520-8107, USA.
Medzhitov R; 1] Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06519-1612, USA [2] Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520-8028, USA [3] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815-6789, USA.; Pokaż więcej
Źródło:: Nature [Nature] 2014 Sep 25; Vol. 513 (7519), pp. 559-63. Date of Electronic Publication: 2014 Jul 13.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Lactic Acid/*metabolism
Macrophages/*metabolism
Macrophages/*pathology
Neoplasms/*metabolism
Neoplasms/*pathology
Animals ; Arginase/genetics ; Arginase/metabolism ; Carcinoma, Lewis Lung/pathology ; Cell Communication/drug effects ; Cell Division/drug effects ; Culture Media, Conditioned/chemistry ; Culture Media, Conditioned/pharmacology ; Female ; Glycolysis ; Homeostasis ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Lactic Acid/pharmacology ; Male ; Melanoma, Experimental/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; RNA, Messenger/analysis ; RNA, Messenger/genetics ; Solubility ; Up-Regulation/drug effects ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism

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