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Wyświetlanie 1-20 z 3164
Tytuł:
Roles of the α 1B -Adrenergic Receptor Phosphorylation Domains in Signaling and Internalization.
Autorzy:
Hernández-Espinosa DA; Departamento de Biología Celular y Desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, Mexico.
Alcántara-Hernández R; Departamento de Biología Celular y Desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, Mexico.
Solís KH; Departamento de Biología Celular y Desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, Mexico.
García-Sáinz JA; Departamento de Biología Celular y Desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, Mexico.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 30; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium*/metabolism
Norepinephrine*/pharmacology
Phosphorylation ; Phorbol Esters ; Receptors, Adrenergic/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis and anti-leukemia activity of phorbol 13,20-diesters and phorbol 12,13,20-triesters.
Autorzy:
Wang, Yan (AUTHOR)
Shan, Yu (AUTHOR)
Feng, Rui (AUTHOR)
Wang, Siyu (AUTHOR)
Li, Linwei (AUTHOR)
Xu, Shu (AUTHOR)
Chen, Yu (AUTHOR)
Feng, Xu (AUTHOR)
Luo, Jinyue (AUTHOR)
Liu, Fei (AUTHOR)
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Źródło:
Journal of Chemical Research. May/Jun2023, Vol. 47 Issue 3, p1-12. 12p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Insertion Depth Modulates Protein Kinase C-δ-C1b Domain Interactions with Membrane Cholesterol as Revealed by MD Simulations.
Autorzy:
Judge PT; Department of Biochemistry, Biophysics & Structural Biology, Washington University in St. Louis, St. Louis, MO 63130, USA.
Overall SA; Laboratory of Physical Chemistry, ETH Zürich, 8093 Zurich, Switzerland.
Barnes AB; Laboratory of Physical Chemistry, ETH Zürich, 8093 Zurich, Switzerland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 27; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Kinase C-delta*
Phorbols*
Humans ; Bryostatins ; Isoenzymes/metabolism ; Phorbol Esters/chemistry ; Lactones/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biphasic alcoholysis coupled with high-speed countercurrent chromatography for high performance on separating phorbol from Croton tiglium Linn extracts.
Autorzy:
Fan JP; Department of Chemical Engineering, Nanchang University, Nanchang, P. R. China.; Key Laboratory of Poyang Lake Ecology and Bio-Resource Utilization of Ministry of Education, Nanchang University, Nanchang, P. R. China.
He BT; Department of Chemical Engineering, Nanchang University, Nanchang, P. R. China.
Gao Y; Department of Chemical Engineering, Nanchang University, Nanchang, P. R. China.
Xie CF; Department of Chemical Engineering, Nanchang University, Nanchang, P. R. China.; Key Laboratory of Poyang Lake Ecology and Bio-Resource Utilization of Ministry of Education, Nanchang University, Nanchang, P. R. China.
Chen HP; Department of Chemical Engineering, Nanchang University, Nanchang, P. R. China.
Peng HL; Department of Chemical Engineering, Nanchang University, Nanchang, P. R. China.
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Źródło:
Journal of separation science [J Sep Sci] 2023 Apr; Vol. 46 (8), pp. e2200984. Date of Electronic Publication: 2023 Feb 25.
Typ publikacji:
Journal Article
MeSH Terms:
Countercurrent Distribution*/methods
Phorbols*
Croton Oil ; Solvents/chemistry ; Plant Extracts/chemistry ; Phorbol Esters ; Chromatography, High Pressure Liquid
SCR Organism:
Croton tiglium
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
12-Deoxyphorbol Esters Induce Growth Arrest and Apoptosis in Human Lung Cancer A549 Cells Via Activation of PKC-δ/PKD/ERK Signaling Pathway.
Autorzy:
Tsai JY; Graduate Institute of Natural Products, Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Rédei D; Department of Pharmacognosy, Interdisciplinary Excellence Centre, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Hohmann J; Department of Pharmacognosy, Interdisciplinary Excellence Centre, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Wu CC; Graduate Institute of Natural Products, Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 14; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Carcinogens/*pharmacology
Cell Proliferation/*drug effects
Phorbol Esters/*pharmacology
Signal Transduction/*drug effects
A549 Cells ; Carcinogens/chemistry ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Humans ; Phorbol Esters/chemistry ; Protein Kinase C/metabolism ; Protein Kinase C-delta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Regulation of CRE-Dependent Transcriptional Activity in a Mouse Suprachiasmatic Nucleus Cell Line.
Autorzy:
Langiu M; Institut für Anatomie II, Dr. Senckenbergische Anatomie, Goethe-Universität Frankfurt, Theodor-Stern-Kai-7, 60590 Frankfurt, Germany.; Monash Institute of Pharmaceutical Science, Monash University, 399 Royal Parade, Parkville, VIC 3052, Australia.
Bechstein P; Institut für Anatomie II, Dr. Senckenbergische Anatomie, Goethe-Universität Frankfurt, Theodor-Stern-Kai-7, 60590 Frankfurt, Germany.
Neumann S; Institut für Anatomie II, Dr. Senckenbergische Anatomie, Goethe-Universität Frankfurt, Theodor-Stern-Kai-7, 60590 Frankfurt, Germany.
Spohn G; German Red Cross Blood Service, Sandhofstrasse-1, 60528 Frankfurt, Germany.
Maronde E; Institut für Anatomie II, Dr. Senckenbergische Anatomie, Goethe-Universität Frankfurt, Theodor-Stern-Kai-7, 60590 Frankfurt, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 13; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Vasoactive Intestinal Peptide*/genetics
Vasoactive Intestinal Peptide*/pharmacology
Vasoactive Intestinal Peptide*/metabolism
Suprachiasmatic Nucleus Neurons*/metabolism
Mice ; Animals ; Cyclic AMP Response Element-Binding Protein/metabolism ; Suprachiasmatic Nucleus/metabolism ; Protein Kinase C/genetics ; Protein Kinase C/metabolism ; Luciferases/metabolism ; Phorbol Esters
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phorbol ester-type diterpenoids from the twigs and leaves of Croton tiglium.
Autorzy:
Jiang L; a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products , Jinan University , Guangzhou 510632 , China.; b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research , Jinan University , Guangzhou 510632 , China.
Zhang YB; a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products , Jinan University , Guangzhou 510632 , China.; b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research , Jinan University , Guangzhou 510632 , China.
Jiang SQ; a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products , Jinan University , Guangzhou 510632 , China.; b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research , Jinan University , Guangzhou 510632 , China.
Zhou YD; a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products , Jinan University , Guangzhou 510632 , China.; b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research , Jinan University , Guangzhou 510632 , China.
Luo D; a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products , Jinan University , Guangzhou 510632 , China.; b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research , Jinan University , Guangzhou 510632 , China.
Niu QW; a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products , Jinan University , Guangzhou 510632 , China.; b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research , Jinan University , Guangzhou 510632 , China.
Qian YR; a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products , Jinan University , Guangzhou 510632 , China.; b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research , Jinan University , Guangzhou 510632 , China.
Li YL; a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products , Jinan University , Guangzhou 510632 , China.; b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research , Jinan University , Guangzhou 510632 , China.
Wang GC; a College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products , Jinan University , Guangzhou 510632 , China.; b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research , Jinan University , Guangzhou 510632 , China.
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Źródło:
Journal of Asian natural products research [J Asian Nat Prod Res] 2017 Dec; Vol. 19 (12), pp. 1191-1197. Date of Electronic Publication: 2017 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents, Phytogenic/*isolation & purification
Croton/*chemistry
Diterpenes/*isolation & purification
Phorbol Esters/*isolation & purification
Plant Components, Aerial/*chemistry
Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/pharmacology ; Diterpenes/chemistry ; Diterpenes/pharmacology ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Phorbol Esters/economics ; Phorbol Esters/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Convenient Oligonucleotide Conjugation via Tandem Staudinger Reaction and Amide Bond Formation at the Internucleotidic Phosphate Position.
Autorzy:
Klabenkova, Kristina V.
Zhdanova, Polina V.
Burakova, Ekaterina A.
Bizyaev, Sergei N.
Fokina, Alesya A.
Stetsenko, Dmitry A.
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Temat:
ARYL esters
AMIDES
PHOSPHATES
FREE groups
CARBOXYLIC acids
PEPTIDES
PHORBOL esters
Źródło:
International Journal of Molecular Sciences; Feb2024, Vol. 25 Issue 4, p2007, 15p
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae.
Autorzy:
Chen H; Key Laboratory of Bioactive Peptides of Yunnan Province/Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China. .; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming 650204, Yunnan, China. .
Zhang R; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, China. .
Luo RH; Key Laboratory of Bioactive Peptides of Yunnan Province/Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China. .
Yang LM; Key Laboratory of Bioactive Peptides of Yunnan Province/Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China. .
Wang RR; Key Laboratory of Bioactive Peptides of Yunnan Province/Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China. .
Hao XJ; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, China. .
Zheng YT; Key Laboratory of Bioactive Peptides of Yunnan Province/Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China. .; KIZ-SU Joint Laboratory of Animal Models and Drug Development, College of Pharmaceutical Sciences, Soochow University, Suzhou 215006, Jiangsu, China. .
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2017 Sep 08; Vol. 22 (9). Date of Electronic Publication: 2017 Sep 08.
Typ publikacji:
Journal Article
MeSH Terms:
Host-Pathogen Interactions*
Anti-HIV Agents/*pharmacology
Euphorbiaceae/*chemistry
HIV-1/*drug effects
Phorbol Esters/*pharmacology
Virion/*drug effects
Virus Replication/*drug effects
APOBEC-3G Deaminase/genetics ; APOBEC-3G Deaminase/metabolism ; Anti-HIV Agents/chemistry ; Anti-HIV Agents/isolation & purification ; Cell Line ; DNA, Viral/antagonists & inhibitors ; DNA, Viral/biosynthesis ; Gene Expression Regulation ; HIV-1/genetics ; HIV-1/metabolism ; HIV-2/drug effects ; HIV-2/genetics ; HIV-2/metabolism ; Humans ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Leukocytes, Mononuclear/virology ; Mutation ; Phorbol Esters/chemistry ; Phorbol Esters/isolation & purification ; Plant Extracts/chemistry ; Primary Cell Culture ; Protein Kinase C/genetics ; Protein Kinase C/metabolism ; Signal Transduction ; T-Lymphocytes/drug effects ; T-Lymphocytes/metabolism ; T-Lymphocytes/virology ; Virion/genetics ; Virion/metabolism ; vif Gene Products, Human Immunodeficiency Virus/deficiency ; vif Gene Products, Human Immunodeficiency Virus/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Plant extracts and compounds for combating schistosomiasis
Autorzy:
El-Seedi, Hesham R.Aff1, Aff2, Aff3, Aff4, IDs1110102209836x_cor1
Khalifa, Shaden A. M.
Mohamed, Azza H.
Yosri, NermeenAff7, Aff8
Zhao, Chao
El-Wakeil, NabilAff10, Aff11
Attia, Nour F.
Xu, Baojun
AbdElhafez, AbdElhafez R.
Boskabady, Mohammad H.
Elseedy, Sherif
Efferth, Thomas
Verpoorte, Rob
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Źródło:
Phytochemistry Reviews: Fundamentals and Perspectives of Natural Products Research. 22(6):1691-1806
Czasopismo naukowe
Szczegóły
Tytuł:
The Novel PKC Activator 10-Methyl-Aplog-1 Combined with JQ1 Induced Strong and Synergistic HIV Reactivation with Tolerable Global T Cell Activation.
Autorzy:
Washizaki A; Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan.
Murata M; Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan.
Seki Y; Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan.
Kikumori M; Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.
Tang Y; Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan.
Tan W; Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan.
Wardani NP; Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan.; Department of Biomedicine, Indonesia International Institute for Life Sciences, Jakarta 13210, Indonesia.
Irie K; Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.
Akari H; Primate Research Institute, Kyoto University, Inuyama 484-8506, Japan.; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
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Źródło:
Viruses [Viruses] 2021 Oct 09; Vol. 13 (10). Date of Electronic Publication: 2021 Oct 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-HIV Agents/*pharmacology
Azepines/*pharmacology
HIV Infections/*drug therapy
HIV-1/*drug effects
Lymphocyte Activation/*drug effects
Triazoles/*pharmacology
Bryostatins/pharmacology ; CD4-Positive T-Lymphocytes/immunology ; Cell Line ; HIV Infections/immunology ; Humans ; Phorbol Esters/pharmacology ; Signal Transduction/drug effects ; Virus Latency/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Monitoring casbene synthase in Jatropha curcas tissues using targeted proteomics.
Autorzy:
de Almeida, Natália Pinto (AUTHOR)
Neto, Domingos Ferreira Mélo (AUTHOR)
Carneiro, Gabriel Reis Alves (AUTHOR)
de Farias, Andreza Raquel Barbosa (AUTHOR)
Domont, Gilberto Barbosa (AUTHOR)
de Paiva Campos, Francisco de Assis (AUTHOR)
Nogueira, Fábio César Sousa (AUTHOR)
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Źródło:
Plant Methods. 2/6/2021, Vol. 17 Issue 1, p1-13. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CYLD Inhibits the Development of Skin Squamous Cell Tumors in Immunocompetent Mice.
Autorzy:
Alameda JP; Molecular and Translational Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.; Biomedical Research Institute I+12, 12 de Octubre University Hospital, 28041 Madrid, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.
García-García VA; Molecular and Translational Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.; Biomedical Research Institute I+12, 12 de Octubre University Hospital, 28041 Madrid, Spain.
López S; Department of Animal Medicine and Surgery, Facultad de Veterinaria, UCM, 28040 Madrid, Spain.
Hernando A; Molecular and Translational Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.; Bionomous Sàrl, PFL Innovation Park, Bâtiment, FCH-1015 Lausanne, Switzerland.
Page A; Molecular and Translational Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.; Biomedical Research Institute I+12, 12 de Octubre University Hospital, 28041 Madrid, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.
Navarro M; Molecular and Translational Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.; Biomedical Research Institute I+12, 12 de Octubre University Hospital, 28041 Madrid, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.
Moreno-Maldonado R; Molecular and Translational Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.; Bio-innova Consulting, 28049 Madrid, Spain.
Paramio JM; Molecular and Translational Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.; Biomedical Research Institute I+12, 12 de Octubre University Hospital, 28041 Madrid, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.
Ramírez Á; Molecular and Translational Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.; Biomedical Research Institute I+12, 12 de Octubre University Hospital, 28041 Madrid, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.
García-Fernández RA; Department of Animal Medicine and Surgery, Facultad de Veterinaria, UCM, 28040 Madrid, Spain.
Casanova ML; Molecular and Translational Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.; Biomedical Research Institute I+12, 12 de Octubre University Hospital, 28041 Madrid, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 28029 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 23; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Squamous Cell/*pathology
Deubiquitinating Enzyme CYLD/*genetics
Skin Neoplasms/*pathology
Animals ; Carcinoma, Squamous Cell/blood supply ; Carcinoma, Squamous Cell/genetics ; Cell Differentiation/genetics ; Cell Proliferation/genetics ; Cells, Cultured ; Deubiquitinating Enzyme CYLD/metabolism ; Genes, Tumor Suppressor ; Immunocompetence ; Keratinocytes/drug effects ; Keratinocytes/pathology ; Mice, Inbred C57BL ; Mice, Inbred DBA ; Mice, Transgenic ; NF-kappa B/metabolism ; Neovascularization, Pathologic/genetics ; Phorbol Esters/toxicity ; Skin Neoplasms/blood supply ; Skin Neoplasms/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Tumor Necrosis Factor-alpha/pharmacology ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functional role and molecular mechanisms underlying prohibitin 2 in platelet mitophagy and activation.
Autorzy:
Hu LL; Department of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Zou K; Department of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Chen Y; Department of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Wu LJ; Department of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Cao J; Department of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Xiong XY; Department of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Wang L; Medicine Lab, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Cheng XS; Department of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Xiao QZ; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
Yang RQ; Department of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2021 May; Vol. 23 (5). Date of Electronic Publication: 2021 Mar 24.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelets/*drug effects
Mitophagy/*genetics
Platelet Activation/*drug effects
Repressor Proteins/*genetics
Carbonyl Cyanide m-Chlorophenyl Hydrazone/analogs & derivatives ; Carbonyl Cyanide m-Chlorophenyl Hydrazone/pharmacology ; Cell Differentiation/drug effects ; Flow Cytometry ; Humans ; Membrane Potential, Mitochondrial ; Mitochondria/drug effects ; Mitochondria/genetics ; Mitophagy/drug effects ; Phorbol Esters/pharmacology ; Platelet Activation/genetics ; Prohibitins ; Signal Transduction/drug effects ; Thrombosis/genetics ; Thrombosis/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bayesian Multi-Trait Analysis Reveals a Useful Tool to Increase Oil Concentration and to Decrease Toxicity in Jatropha curcas L.
Autorzy:
Silva Junqueira V; Animal Science Department, Federal University of Viçosa, Viçosa, Minas Gerais, zipcode: 36570-000, Brazil.
Azevedo Peixoto Ld; Biology Department, Federal University Viçosa, Viçosa, Minas Gerais, zipcode: 36570-000, Brazil.
Galvêas Laviola B; Empresa Brasileira de Pesquisa Agropecuária, Embrapa Agroenergia, Parque Estação Biológica-PqEB s/n, Asa Norte, zipcode: 70770901, Brasília, Brazil.
Lopes Bhering L; Biology Department, Federal University Viçosa, Viçosa, Minas Gerais, zipcode: 36570-000, Brazil.
Mendonça S; Empresa Brasileira de Pesquisa Agropecuária, Embrapa Agroenergia, Parque Estação Biológica-PqEB s/n, Asa Norte, zipcode: 70770901, Brasília, Brazil.
Agostini Costa Tda S; Empresa Brasileira de Pesquisa Agropecuária, Centro Nacional de Pesquisa de Recursos Genéticos e Biotecnologia, Parque Estação Biológica, PqEB, W5 Norte, Final PqEB, zipcode: 70770917, Brasília, Brazil.
Antoniassi R; Empresa Brasileira de Pesquisa Agropecuária, Centro Nacional de Pesquisa de Tecnologia Agroindustrial de Alimentos, Avenida das Americas 29501 Guaratiba, zipcode: 23020470, Rio de Janeiro, Brazil.
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Źródło:
PloS one [PLoS One] 2016 Jun 09; Vol. 11 (6), pp. e0157038. Date of Electronic Publication: 2016 Jun 09 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Quantitative Trait, Heritable*
Jatropha/*genetics
Phorbol Esters/*metabolism
Plant Oils/*chemistry
Seeds/*genetics
Bayes Theorem ; Genetic Variation ; Jatropha/growth & development ; Phenotype ; Phorbol Esters/toxicity ; Seeds/growth & development
Czasopismo naukowe
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