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Wyszukujesz frazę ""Phosphoenolpyruvate Carboxykinase \(GTP\)"" wg kryterium: Temat


Tytuł :
Comparative transcriptome analysis reveals that PCK1 is a potential gene affecting IMF deposition in buffalo.
Autorzy :
Huang J; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning, 530005, Guangxi, China. .; College of Life Sciences, Xinyang Normal University, Xinyang, 464000, Henan, China. .
Feng X; College of Life Sciences, Xinyang Normal University, Xinyang, 464000, Henan, China.
Zhu R; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning, 530005, Guangxi, China.
Guo D; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning, 530005, Guangxi, China.
Wei Y; College of Life Sciences, Xinyang Normal University, Xinyang, 464000, Henan, China.
Cao X; College of Life Sciences, Xinyang Normal University, Xinyang, 464000, Henan, China.
Ma Y; College of Life Sciences, Xinyang Normal University, Xinyang, 464000, Henan, China.; School of Agriculture, Ningxia University, Yinchuan, 750021, Ningxia, China.
Shi D; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning, 530005, Guangxi, China.
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Źródło :
BMC genomics [BMC Genomics] 2020 Oct 12; Vol. 21 (1), pp. 710. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article
MeSH Terms :
Adipose Tissue*/metabolism
Buffaloes*/genetics
Phosphoenolpyruvate Carboxykinase (GTP)*/genetics
Transcriptome*
Animals ; Cattle ; Cells, Cultured ; China ; Gene Expression Profiling ; Mice ; Muscle, Skeletal/metabolism
Czasopismo naukowe
Tytuł :
Hepatocellular carcinoma cell-derived extracellular vesicles encapsulated microRNA-584-5p facilitates angiogenesis through PCK1-mediated nuclear factor E2-related factor 2 signaling pathway.
Autorzy :
Shao Z; Department of Organ Transplantation and Hepatobiliary, The First Affiliated Hospital of China Medical University, Shenyang 110000, PR China; The Key Laboratory of Organ Transplantation of Liaoning Province, Shenyang 110000, PR China.
Pan Q; Department of Organ Transplantation and Hepatobiliary, The First Affiliated Hospital of China Medical University, Shenyang 110000, PR China; The Key Laboratory of Organ Transplantation of Liaoning Province, Shenyang 110000, PR China.
Zhang Y; Department of Organ Transplantation and Hepatobiliary, The First Affiliated Hospital of China Medical University, Shenyang 110000, PR China; The Key Laboratory of Organ Transplantation of Liaoning Province, Shenyang 110000, PR China. Electronic address: .
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Źródło :
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2020 Aug; Vol. 125, pp. 105789. Date of Electronic Publication: 2020 Jun 06.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*metabolism
Extracellular Vesicles/*metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
Liver Neoplasms/*metabolism
MicroRNAs/*metabolism
NF-E2-Related Factor 2/*metabolism
Neovascularization, Pathologic/*metabolism
Phosphoenolpyruvate Carboxykinase (GTP)/*metabolism
Animals ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Coculture Techniques ; Extracellular Vesicles/genetics ; Extracellular Vesicles/ultrastructure ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/genetics ; Microscopy, Electron, Transmission ; NF-E2-Related Factor 2/genetics ; Neovascularization, Pathologic/genetics ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Signal Transduction/genetics ; Up-Regulation ; Vascular Endothelial Growth Factor A/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Cytosolic phosphoenolpyruvate carboxykinase is expressed in α-cells from human and murine pancreas.
Autorzy :
Westermeier F; FH JOANNEUM Gesellschaft mbH University of Applied Sciences, Institute of Biomedical Science, Department of Health Studies, Graz, Austria.
Holyoak T; Department of Biology, University of Waterloo, Waterloo, Ontario, Canada.
Gatica R; Escuela de Veterinaria, Facultad de Ciencias, Universidad Mayor, Santiago, Chile.
Martínez F; Centro de Microscopía Avanzada, CMA-BIO BIO, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Negrón M; Centro de Microscopía Avanzada, CMA-BIO BIO, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Yáñez AJ; Instituto de Bioquímica y Microbiología, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile.
Nahmias D; Anatomía patológica, Hospital Puerto Montt, Puerto Montt, Chile.
Nualart F; Centro de Microscopía Avanzada, CMA-BIO BIO, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Burbulis I; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Charlottesville, Virginia.; Escuela de Medicina, Universidad San Sebastián, Sede de la Patagonia, Puerto Montt, Chile.
Bertinat R; Centro de Microscopía Avanzada, CMA-BIO BIO, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2020 Jan; Vol. 235 (1), pp. 166-175. Date of Electronic Publication: 2019 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Enzymologic/*physiology
Glucagon-Secreting Cells/*enzymology
Intracellular Signaling Peptides and Proteins/*metabolism
Phosphoenolpyruvate Carboxykinase (GTP)/*metabolism
Animals ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Male ; Mice ; Pancreas/enzymology ; Pancreas/metabolism ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Rats
Czasopismo naukowe
Tytuł :
TCTP participates in hepatic metabolism by regulating gene expression involved in insulin resistance.
Autorzy :
Dong K; Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jie Fang Avenue, Hankou, Wuhan, Hubei 430030, China. Electronic address: .
Zhao Q; College of Life Sciences, Wuhan University, NO.299 Ba Yi Avenue, Wuchang, Wuhan 430072, China. Electronic address: .
Xue Y; Laboratory for Genome Regulation and Human Health, ABLife Inc., Optics Valley International Biomedical Park, Building 18-2, East Lake High-Tech Development Zone, 388 Gaoxin 2nd Road, Wuhan, Hubei 430075, China; Center for Genome Analysis, ABLife Inc., Optics Valley International Biomedical Park, Building 18-1, East Lake High-Tech Development Zone, 388 Gaoxin 2nd Road, Wuhan, Hubei 430075, China. Electronic address: .
Wei Y; Center for Genome Analysis, ABLife Inc., Optics Valley International Biomedical Park, Building 18-1, East Lake High-Tech Development Zone, 388 Gaoxin 2nd Road, Wuhan, Hubei 430075, China. Electronic address: .
Zhang Y; ABLife BioBigData Institute, Optics Valley International Biomedical Park, Building 18-1, East Lake High-Tech Development Zone, 388 Gaoxin 2nd Road, Wuhan, Hubei 430075, China. Electronic address: .
Yang Y; Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jie Fang Avenue, Hankou, Wuhan, Hubei 430030, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Feb 05; Vol. 768, pp. 145263. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*metabolism
Gene Expression Regulation/*genetics
Insulin Resistance/*genetics
Lipid Metabolism/*genetics
Liver/*metabolism
Alternative Splicing/genetics ; Apoptosis/genetics ; Blood Glucose/genetics ; Cell Line, Tumor ; Cholesterol/blood ; Diet, High-Fat ; Gluconeogenesis/genetics ; Glucose/metabolism ; Glycerophospholipids/metabolism ; Glycolysis/genetics ; Hep G2 Cells ; Hepatocytes/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; NF-kappa B/genetics ; Non-alcoholic Fatty Liver Disease/genetics ; Non-alcoholic Fatty Liver Disease/pathology ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; RNA Interference ; RNA, Small Interfering/genetics ; Signal Transduction/genetics ; Transcriptional Activation/genetics ; Transcriptome/genetics ; Triglycerides/blood ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł :
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Osteogenic Differentiation by Modulating AMPK/ULK1-Dependent Autophagy.
Autorzy :
Li Z; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
Liu X; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
Zhu Y; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
Du Y; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
Liu X; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
Lv L; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
Zhang X; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
Liu Y; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
Zhang P; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
Zhou Y; Department of Prosthodontics, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.; National Engineering Lab for Digital and Material Technology of Stomatology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Peking University, Beijing, People's Republic of China.
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Źródło :
Stem cells (Dayton, Ohio) [Stem Cells] 2019 Dec; Vol. 37 (12), pp. 1542-1555. Date of Electronic Publication: 2019 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
AMP-Activated Protein Kinases/*metabolism
Autophagy/*physiology
Autophagy-Related Protein-1 Homolog/*metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
Osteogenesis/*physiology
Phosphoenolpyruvate Carboxykinase (GTP)/*metabolism
Bone Development/physiology ; Bone and Bones/cytology ; Cell Line ; Humans ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/metabolism ; Mitochondria/metabolism ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; RNA Interference ; RNA, Small Interfering/genetics
Czasopismo naukowe
Tytuł :
Hepatocyte expression of the micropeptide adropin regulates the liver fasting response and is enhanced by caloric restriction.
Autorzy :
Banerjee S; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Ghoshal S; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Stevens JR; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
McCommis KS; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri, USA; Center for Cardiovascular Research, Saint Louis University School of Medicine, St. Louis, Missouri, USA; Saint Louis University Liver Center, Saint Louis University School of Medicine, St. Louis, Missouri USA.
Gao S; Department of Metabolism and Aging, Scripps Research Institute, Jupiter, Florida, USA.
Castro-Sepulveda M; Laboratorio de Ciencias del Ejercicio. Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.
Mizgier ML; Departamento de Ciencias de la SaludCarrera de Nutrición y Dietética and Departamento de Nutrición, Diabetes y Metabolismo, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Girardet C; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Kumar KG; Department of Metabolism and Aging, Scripps Research Institute, Jupiter, Florida, USA.
Galgani JE; Departamento de Ciencias de la SaludCarrera de Nutrición y Dietética and Departamento de Nutrición, Diabetes y Metabolismo, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Niehoff ML; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri, USA; Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, Saint Louis University School of Medicine; Research Service, John Cochran Division, Saint Louis Veterans Affairs Medical Center, Missouri, USA.
Farr SA; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri, USA; Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, Saint Louis University School of Medicine; Research Service, John Cochran Division, Saint Louis Veterans Affairs Medical Center, Missouri, USA.
Zhang J; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Butler AA; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, USA; Department of Metabolism and Aging, Scripps Research Institute, Jupiter, Florida, USA; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University School of Medicine, St. Louis, Missouri, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Oct 02; Vol. 295 (40), pp. 13753-13768. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Caloric Restriction*
Fasting*
Gene Expression Regulation*
Hepatocytes/*metabolism
Intercellular Signaling Peptides and Proteins/*biosynthesis
Liver/*metabolism
Animals ; Cyclic AMP-Dependent Protein Kinases/genetics ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Gluconeogenesis/genetics ; Hepatocytes/cytology ; Intercellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/biosynthesis ; Intracellular Signaling Peptides and Proteins/genetics ; Liver/cytology ; Mice ; Mice, Knockout ; Phosphoenolpyruvate Carboxykinase (GTP)/biosynthesis ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Knockdown of the Sonic Hedgehog (SHH) Gene Inhibits Proliferation of Hep3B and SMMC-7721 Hepatocellular Carcinoma Cells via the PI3K/Akt/PCK1 Signaling Pathway.
Autorzy :
Chen Y; Department of Gastroenterology, The First Peoples' Hospital of Tianmen City, Tianmen, Hubei, China (mainland).
Zhu W; Department of Gastroenterology, The First Peoples' Hospital of Tianmen City, Tianmen, Hubei, China (mainland).
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Źródło :
Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2019 Aug 13; Vol. 25, pp. 6023-6033. Date of Electronic Publication: 2019 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*genetics
Hedgehog Proteins/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
Phosphoenolpyruvate Carboxykinase (GTP)/*genetics
Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; G1 Phase Cell Cycle Checkpoints ; Gene Expression Regulation, Neoplastic/drug effects ; Glycolysis ; Hedgehog Proteins/metabolism ; Hep G2 Cells ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; Liver Neoplasms/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphoenolpyruvate Carboxykinase (ATP)/metabolism ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Cis-9, Trans-11 Conjugated Linoleic Acid Reduces Phosphoenolpyruvate Carboxykinase Expression and Hepatic Glucose Production in HepG2 Cells.
Autorzy :
Chai BK; Department of Biomedical Sciences, Faculty of Science, University of Nottingham Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia.
Al-Shagga M; Department of Biomedical Sciences, Faculty of Science, University of Nottingham Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia.
Pan Y; Department of Biomedical Sciences, Faculty of Science, University of Nottingham Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia.
Then SM; Department of Biomedical Sciences, Faculty of Science, University of Nottingham Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia.
Ting KN; Department of Biomedical Sciences, Faculty of Science, University of Nottingham Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia.
Loh HS; School of Biosciences, Faculty of Science, University of Nottingham Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor Darul Ehsan, Malaysia.
Mohankumar SK; TIFAC CORE in Herbal Drugs, Department of Pharmacognosy, JSS College of Pharmacy (Ooty), JSS Academy of Higher Education & Research, Rocklands, Udhagamandalam, 643001, Tamil Nadu, India.
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Źródło :
Lipids [Lipids] 2019 Jun; Vol. 54 (6-7), pp. 369-379. Date of Electronic Publication: 2019 May 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucose/*biosynthesis
Hepatocytes/*metabolism
Intracellular Signaling Peptides and Proteins/*antagonists & inhibitors
Linoleic Acids, Conjugated/*pharmacology
Phosphoenolpyruvate Carboxykinase (GTP)/*antagonists & inhibitors
Animals ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Gene Expression Profiling ; Gluconeogenesis/drug effects ; Gluconeogenesis/genetics ; Hep G2 Cells ; Hepatocytes/chemistry ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Linoleic Acids, Conjugated/chemistry ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; Rats ; Reverse Transcriptase Polymerase Chain Reaction ; Stereoisomerism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
The phosphoenolpyruvate carboxykinase (PEPCK) inhibitor, 3-mercaptopicolinic acid (3-MPA), induces myogenic differentiation in C2C12 cells.
Autorzy :
Brearley MC; School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, LE12 5RD, UK.; Department of Medicine-Cardiology, University of California, Los Angeles, CA, USA.
Daniel ZCTR; School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, LE12 5RD, UK.
Loughna PT; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, LE12 5RD, UK.
Parr T; School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, LE12 5RD, UK.
Brameld JM; School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, LE12 5RD, UK. .
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Źródło :
Scientific reports [Sci Rep] 2020 Dec 17; Vol. 10 (1), pp. 22177. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation/*drug effects
Enzyme Inhibitors/*pharmacology
Muscle Development/*drug effects
Phosphoenolpyruvate Carboxykinase (ATP)/*antagonists & inhibitors
Phosphoenolpyruvate Carboxykinase (GTP)/*antagonists & inhibitors
Picolinic Acids/*pharmacology
Animals ; Biomarkers ; Cell Line ; Cell Proliferation/drug effects ; Cells, Cultured ; Gene Expression Regulation/drug effects ; Gluconeogenesis/genetics ; Isoenzymes ; Mice ; Muscle Cells ; Promoter Regions, Genetic ; RNA, Messenger/genetics ; Serine/biosynthesis
Czasopismo naukowe
Tytuł :
Crocins from Crocus sativus L. in the Management of Hyperglycemia. In Vivo Evidence from Zebrafish.
Autorzy :
Kakouri E; Laboratory of Chemistry, Department of Food Science & Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, 111855 Athens, Greece.
Agalou A; Developmental Biology, Biomedical Research Foundation Academy of Athens, 11527 Athens, Greece.
Kanakis C; Laboratory of Chemistry, Department of Food Science & Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, 111855 Athens, Greece.
Beis D; Developmental Biology, Biomedical Research Foundation Academy of Athens, 11527 Athens, Greece.
Tarantilis PA; Laboratory of Chemistry, Department of Food Science & Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, 111855 Athens, Greece.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Nov 10; Vol. 25 (22). Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Carotenoids/*pharmacology
Crocus/*chemistry
Hyperglycemia/*drug therapy
Animals ; Animals, Genetically Modified ; Blood Glucose/metabolism ; Carotenoids/analysis ; Gluconeogenesis ; Glucose/metabolism ; Insulin/metabolism ; Insulin-Secreting Cells/metabolism ; Ions ; Pancreas/embryology ; Pancreas/metabolism ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; Plant Extracts/pharmacology ; Zebrafish
Czasopismo naukowe
Tytuł :
Fructose Consumption by Adult Rats Exposed to Dexamethasone In Utero Changes the Phenotype of Intestinal Epithelial Cells and Exacerbates Intestinal Gluconeogenesis.
Autorzy :
Pereira GA; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP 05508-000, Brazil.
Sodré FS; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP 05508-000, Brazil.
Murata GM; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP 05508-000, Brazil.
Amaral AG; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP 05508-000, Brazil.
Payolla TB; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP 05508-000, Brazil.
Campos CV; Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, SP 13083-887, Brazil.
Sato FT; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP 05508-000, Brazil.
Anhê GF; Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, SP 13083-887, Brazil.
Bordin S; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP 05508-000, Brazil.
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Źródło :
Nutrients [Nutrients] 2020 Oct 07; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article
MeSH Terms :
Gluconeogenesis*
Prenatal Exposure Delayed Effects*
Dexamethasone/*adverse effects
Dietary Carbohydrates/*adverse effects
Epithelial Cells/*pathology
Fructose/*adverse effects
Intestinal Mucosa/*cytology
Intestinal Mucosa/*metabolism
Jejunum/*metabolism
Maternal Exposure/*adverse effects
Maternal-Fetal Exchange/*physiology
Animal Nutritional Physiological Phenomena/physiology ; Animals ; Female ; Glucose Transporter Type 2/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Lipid Metabolism ; Maternal Nutritional Physiological Phenomena/physiology ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; Pregnancy ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Zbtb7c is a critical gluconeogenic transcription factor that induces glucose-6-phosphatase and phosphoenylpyruvate carboxykinase 1 genes expression during mice fasting.
Autorzy :
Choi WI; Leading-edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital, Daegu 41944, South Korea; Bio-Medical Research Institute, Kyungpook National University Hospital, Daegu 41940, South Korea.
Yoon JH; BK21 plus project of Medical Science, Department of Biochemistry and Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul 03722, Republic of Korea.
Song JY; BK21 plus project of Medical Science, Department of Biochemistry and Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul 03722, Republic of Korea.
Jeon BN; BK21 plus project of Medical Science, Department of Biochemistry and Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul 03722, Republic of Korea.
Park JM; BK21 plus project of Medical Science, Department of Biochemistry and Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul 03722, Republic of Korea.
Koh DI; BK21 plus project of Medical Science, Department of Biochemistry and Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul 03722, Republic of Korea.
Ahn YH; BK21 plus project of Medical Science, Department of Biochemistry and Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul 03722, Republic of Korea.
Kim KS; BK21 plus project of Medical Science, Department of Biochemistry and Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul 03722, Republic of Korea.
Lee IK; Leading-edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital, Daegu 41944, South Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, South Korea.
Hur MW; BK21 plus project of Medical Science, Department of Biochemistry and Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul 03722, Republic of Korea. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2019 Jun; Vol. 1862 (6), pp. 643-656. Date of Electronic Publication: 2019 Apr 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fasting*
Gene Expression Regulation*
Gluconeogenesis/*physiology
Glucose-6-Phosphatase/*genetics
Intracellular Signaling Peptides and Proteins/*genetics
Phosphoenolpyruvate Carboxykinase (GTP)/*genetics
Proteins/*metabolism
Transcription Factors/*metabolism
Zinc Fingers/*physiology
Animals ; Blood Glucose ; DNA-Binding Proteins/metabolism ; Fatty Acids/biosynthesis ; Forkhead Box Protein O1/metabolism ; Gluconeogenesis/genetics ; Glucose/metabolism ; Glucose-6-Phosphatase/metabolism ; HEK293 Cells ; Hep G2 Cells ; Hepatocytes/metabolism ; Histone Deacetylases/metabolism ; Homeostasis ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Models, Animal ; Mutagenesis, Site-Directed ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; Promoter Regions, Genetic ; Proteins/genetics ; Transcriptome ; Zinc Fingers/genetics
Czasopismo naukowe
Tytuł :
Phosphoenolpyruvate carboxykinase is involved in antiviral immunity against Bombyx mori nucleopolyhedrovirus.
Autorzy :
Guo H; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China; Chongqing Key Laboratory of Sericultural Science, Chongqing Engineering and Technology Research Center for Novel Silk Materials, Southwest University, Chongqing, 400715, China.
Xu G; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China.
Wang B; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China.
Xia F; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China.
Sun Q; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China.
Wang Y; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China.
Xie E; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China.
Lu Z; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China; Chongqing Key Laboratory of Sericultural Science, Chongqing Engineering and Technology Research Center for Novel Silk Materials, Southwest University, Chongqing, 400715, China.
Jiang L; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China; Chongqing Key Laboratory of Sericultural Science, Chongqing Engineering and Technology Research Center for Novel Silk Materials, Southwest University, Chongqing, 400715, China. Electronic address: .
Xia Q; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400715, China; Chongqing Key Laboratory of Sericultural Science, Chongqing Engineering and Technology Research Center for Novel Silk Materials, Southwest University, Chongqing, 400715, China. Electronic address: .
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Źródło :
Developmental and comparative immunology [Dev Comp Immunol] 2019 Mar; Vol. 92, pp. 193-198. Date of Electronic Publication: 2018 Nov 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bombyx/*physiology
Insect Proteins/*metabolism
Nucleopolyhedroviruses/*physiology
Phosphoenolpyruvate Carboxykinase (ATP)/*metabolism
Phosphoenolpyruvate Carboxykinase (GTP)/*metabolism
Virus Diseases/*immunology
3' Untranslated Regions/genetics ; Animals ; Bombyx/virology ; Cloning, Molecular ; Immunity, Innate ; Insect Proteins/genetics ; Phosphoenolpyruvate Carboxykinase (ATP)/genetics ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Viral Load ; Virus Replication
Czasopismo naukowe
Tytuł :
PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27 axis.
Autorzy :
Tuo L; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Xiang J; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Pan X; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Hu J; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Tang H; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Liang L; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Xia J; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Hu Y; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Zhang W; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Huang A; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China. .
Wang K; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China. .
Tang N; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China. .
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Źródło :
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2019 Feb 04; Vol. 38 (1), pp. 50. Date of Electronic Publication: 2019 Feb 04.
Typ publikacji :
Journal Article
MeSH Terms :
AMP-Activated Protein Kinases/*metabolism
Calcium-Binding Proteins/*metabolism
Carcinoma, Hepatocellular/*pathology
G1 Phase Cell Cycle Checkpoints/*physiology
Intracellular Signaling Peptides and Proteins/*metabolism
Liver Neoplasms/*pathology
Phosphoenolpyruvate Carboxykinase (GTP)/*metabolism
AMP-Activated Protein Kinases/genetics ; Animals ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Cyclin-Dependent Kinases/metabolism ; Down-Regulation ; E2F Transcription Factors/metabolism ; G1 Phase Cell Cycle Checkpoints/drug effects ; G1 Phase Cell Cycle Checkpoints/genetics ; Gene Knockdown Techniques ; Glucose/metabolism ; Humans ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Intracellular Signaling Peptides and Proteins/genetics ; Liver Neoplasms/drug therapy ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Male ; Metformin/pharmacology ; Metformin/therapeutic use ; Mice ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Up-Regulation ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
PEPCK1 Antisense Oligonucleotide Prevents Adiposity and Impairs Hepatic Glycogen Synthesis in High-Fat Male Fed Rats.
Autorzy :
Beddow SA; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.; West Haven Veterans Affairs Medical Center, West Haven, Connecticut.
Gattu AK; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.; West Haven Veterans Affairs Medical Center, West Haven, Connecticut.
Vatner DF; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Paolella L; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.; West Haven Veterans Affairs Medical Center, West Haven, Connecticut.
Alqarzaee A; West Haven Veterans Affairs Medical Center, West Haven, Connecticut.
Tashkandi N; West Haven Veterans Affairs Medical Center, West Haven, Connecticut.
Popov VB; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Church CD; Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut.
Rodeheffer MS; Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut.
Cline GW; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Geisler JG; Mitochon Pharmaceutical, Blue Bell, Pennsylvania.
Bhanot S; Ionis Pharmaceuticals, Carlsbad, California.
Samuel VT; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.; West Haven Veterans Affairs Medical Center, West Haven, Connecticut.
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Źródło :
Endocrinology [Endocrinology] 2019 Jan 01; Vol. 160 (1), pp. 205-219.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Adiposity*
Diabetes Mellitus, Type 2/*enzymology
Intracellular Signaling Peptides and Proteins/*genetics
Liver/*metabolism
Liver Glycogen/*biosynthesis
Oligonucleotides, Antisense/*genetics
Phosphoenolpyruvate Carboxykinase (GTP)/*genetics
Adipose Tissue, White/metabolism ; Animals ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/physiopathology ; Diet, High-Fat/adverse effects ; Glucokinase/genetics ; Glucokinase/metabolism ; Humans ; Insulin/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Lipogenesis ; Male ; Mice ; Mice, Inbred C57BL ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Duodenal-Jejunal Exclusion Surgery Improves Type 2 Diabetes in a Rat Model Through Regulation of Early Glucose Metabolism.
Autorzy :
Guan W; Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Cui Y; Department of Endocrinology, the Dezhou People's Hospital, Dezhou, China.
Bu H; Department of Nutriology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Liu J; Department of Endocrinology, the Dezhou People's Hospital, Dezhou, China.
Zhao S; Department of Nutriology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhao Q; Department of Endocrinology, the Dezhou People's Hospital, Dezhou, China.
Ma X; Department of Nutriology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address: .
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Źródło :
Canadian journal of diabetes [Can J Diabetes] 2020 Jul; Vol. 44 (5), pp. 401-406.e1. Date of Electronic Publication: 2020 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Bariatric Surgery*
Blood Glucose/*metabolism
Diabetes Mellitus, Type 2/*surgery
Duodenum/*surgery
Gluconeogenesis/*genetics
Jejunum/*surgery
Liver/*metabolism
Stomach/*surgery
Anastomosis, Surgical ; Animals ; Body Weight ; Diabetes Mellitus, Type 2/metabolism ; Glucose Tolerance Test ; Glucose Transporter Type 2/genetics ; Glucose Transporter Type 2/metabolism ; Glucose-6-Phosphatase/genetics ; Glucose-6-Phosphatase/metabolism ; Insulin/metabolism ; Insulin Receptor Substrate Proteins/genetics ; Insulin Receptor Substrate Proteins/metabolism ; Insulin Resistance ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Jejunum/metabolism ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; RNA, Messenger/metabolism ; Rats
Czasopismo naukowe
Tytuł :
Phosphoenolpyruvate carboxykinase cytosolic and mitochondrial isoforms are expressed and active during hypoxia in the white shrimp Litopenaeus vannamei.
Autorzy :
Reyes-Ramos CA; Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera a Ejido La Victoria Km. 0.6, Hermosillo, Sonora 83304, Mexico.
Peregrino-Uriarte AB; Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera a Ejido La Victoria Km. 0.6, Hermosillo, Sonora 83304, Mexico.
Cota-Ruiz K; Department of Chemistry, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA; El Colegio de Chihuahua, Calle Partido Díaz 4723 Esquina con Anillo Envolvente del PRONAF, Ciudad Juárez, Chihuahua 32310, Mexico.
Valenzuela-Soto EM; Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera a Ejido La Victoria Km. 0.6, Hermosillo, Sonora 83304, Mexico.
Leyva-Carrillo L; Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera a Ejido La Victoria Km. 0.6, Hermosillo, Sonora 83304, Mexico.
Yepiz-Plascencia G; Centro de Investigación en Alimentación y Desarrollo, A.C. Carretera a Ejido La Victoria Km. 0.6, Hermosillo, Sonora 83304, Mexico. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2018 Dec; Vol. 226, pp. 1-9. Date of Electronic Publication: 2018 Aug 11.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Cytosol/*enzymology
Hypoxia/*enzymology
Mitochondria/*enzymology
Penaeidae/*physiology
Phosphoenolpyruvate Carboxykinase (GTP)/*metabolism
Amino Acid Sequence ; Animals ; Aquaculture ; Conserved Sequence ; Cytosol/metabolism ; Databases, Protein ; Gills/enzymology ; Gills/growth & development ; Gills/metabolism ; Hepatopancreas/enzymology ; Hepatopancreas/growth & development ; Hepatopancreas/metabolism ; Hypoxia/metabolism ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Mitochondria/metabolism ; Muscle, Skeletal/enzymology ; Muscle, Skeletal/growth & development ; Muscle, Skeletal/metabolism ; Organ Specificity ; Penaeidae/growth & development ; Phosphoenolpyruvate Carboxykinase (GTP)/chemistry ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Phylogeny ; Sequence Alignment ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
Effect of feeding type 2 diabetes mellitus rats with synbiotic yogurt sweetened with monk fruit extract on serum lipid levels and hepatic AMPK (5' adenosine monophosphate-activated protein kinase) signaling pathway.
Autorzy :
Ban Q; College of Food Science, Northeast Agricultural University, Harbin, 150030, China and Key Laboratory of Dairy Science of Ministry of Education, Northeast Agricultural University, Harbin 150030, China. .
Cheng J; College of Food Science, Northeast Agricultural University, Harbin, 150030, China.
Sun X; College of Food Science, Northeast Agricultural University, Harbin, 150030, China and Key Laboratory of Dairy Science of Ministry of Education, Northeast Agricultural University, Harbin 150030, China. .
Jiang Y; College of Food Science, Northeast Agricultural University, Harbin, 150030, China and Key Laboratory of Dairy Science of Ministry of Education, Northeast Agricultural University, Harbin 150030, China. .
Guo M; Key Laboratory of Dairy Science of Ministry of Education, Northeast Agricultural University, Harbin 150030, China. and Department of Nutrition and Food Sciences, College of Agriculture and Life Sciences, University of Vermont, Burlington, VT 05405, USA.
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Źródło :
Food & function [Food Funct] 2020 Sep 23; Vol. 11 (9), pp. 7696-7706.
Typ publikacji :
Journal Article
MeSH Terms :
Cucurbitaceae*
Synbiotics*
Yogurt*
AMP-Activated Protein Kinases/*metabolism
Diabetes Mellitus, Type 2/*metabolism
Lipids/*blood
Liver/*enzymology
Animals ; Body Weight ; Diabetes Mellitus, Type 2/diet therapy ; Diabetes Mellitus, Type 2/prevention & control ; Gene Expression Profiling ; Glucose-6-Phosphatase/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Linoleic Acid/metabolism ; Male ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; Plant Extracts ; Rats ; Respiration ; Signal Transduction ; Sweetening Agents ; alpha-Linolenic Acid/metabolism
Czasopismo naukowe
Tytuł :
Cytosolic phosphoenolpyruvate carboxykinase is a response gene involved in porcine adipocyte adaptation to heat stress.
Autorzy :
Qu H; Department of Animal Sciences, Purdue University, West Lafayette, IN.
Ajuwon KM; Department of Animal Sciences, Purdue University, West Lafayette, IN.
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Źródło :
Journal of animal science [J Anim Sci] 2018 May 04; Vol. 96 (5), pp. 1724-1735.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptation, Physiological*
Heat-Shock Response*
Phosphoenolpyruvate Carboxykinase (GTP)/*metabolism
Swine/*physiology
Adipocytes/physiology ; Animals ; Animals, Newborn ; Biomarkers/metabolism ; Cells, Cultured ; Endoplasmic Reticulum Stress ; Gene Expression Regulation ; HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/metabolism ; Male ; Phosphoenolpyruvate Carboxykinase (GTP)/antagonists & inhibitors ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Picolinic Acids/pharmacology ; RNA, Messenger/metabolism ; Swine/genetics ; Triglycerides/metabolism
Czasopismo naukowe
Tytuł :
Cardiac Transcriptome Analysis Reveals Nr4a1 Mediated Glucose Metabolism Dysregulation in Response to High-Fat Diet.
Autorzy :
Men L; Department of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Hui W; Department of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Guan X; Department of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Song T; Department of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Wang X; Department of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Zhang S; Department of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Chen X; Department of Pharmacology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
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Źródło :
Genes [Genes (Basel)] 2020 Jun 29; Vol. 11 (7). Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcriptome*
Diet, High-Fat/*adverse effects
Glucose/*metabolism
Myocardium/*metabolism
Nuclear Receptor Subfamily 4, Group A, Member 1/*metabolism
Obesity/*metabolism
Animals ; Cell Line ; Fibroblast Growth Factors/genetics ; Fibroblast Growth Factors/metabolism ; Glucose Transporter Type 3/genetics ; Glucose Transporter Type 3/metabolism ; Hydroxymethylglutaryl-CoA Synthase/genetics ; Hydroxymethylglutaryl-CoA Synthase/metabolism ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Nuclear Receptor Subfamily 4, Group A, Member 1/genetics ; Obesity/etiology ; Obesity/genetics ; Phosphoenolpyruvate Carboxykinase (GTP)/genetics ; Phosphoenolpyruvate Carboxykinase (GTP)/metabolism ; Rats
Czasopismo naukowe

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