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Wyszukujesz frazę ""Phospholipases A2"" wg kryterium: Temat


Tytuł :
Trans triacylglycerols from dairy products and industrial hydrogenated oil exhibit different effects on the function of human umbilical vein endothelial cells via modulating phospholipase A2/arachidonic acid metabolism pathways.
Autorzy :
Wei M; State Key Laboratory of Food Science and Technology, Institute for Advanced Study, Nanchang University, Nanchang, Jiangxi 330047, China.
Zhou RL; State Key Laboratory of Food Science and Technology, Institute for Advanced Study, Nanchang University, Nanchang, Jiangxi 330047, China.
Luo T; State Key Laboratory of Food Science and Technology, Institute for Advanced Study, Nanchang University, Nanchang, Jiangxi 330047, China.
Deng ZY; State Key Laboratory of Food Science and Technology, Institute for Advanced Study, Nanchang University, Nanchang, Jiangxi 330047, China.
Li J; State Key Laboratory of Food Science and Technology, Institute for Advanced Study, Nanchang University, Nanchang, Jiangxi 330047, China. Electronic address: .
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Źródło :
Journal of dairy science [J Dairy Sci] 2021 Jun; Vol. 104 (6), pp. 6399-6414. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article
MeSH Terms :
Arachidonic Acids*
Phospholipases A2, Cytosolic*
Animals ; Human Umbilical Vein Endothelial Cells ; Phospholipases A2 ; Triglycerides
Czasopismo naukowe
Tytuł :
Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism.
Autorzy :
Lee ML; Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Matsunaga H; Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Sugiura Y; Department of Biochemistry, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Hayasaka T; Department of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Yamamoto I; Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Ishimoto T; Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Imoto D; Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Suematsu M; Department of Biochemistry, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Iijima N; National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Osaka, Japan.; Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan.
Kimura K; Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Diano S; Department of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, USA.; Department of Cellular and Molecular Physiology, Yale School of Medicine, Yale University, New Haven, CT, USA.
Toda C; Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan. .
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Źródło :
Nature communications [Nat Commun] 2021 Apr 20; Vol. 12 (1), pp. 2330. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucose/*metabolism
Phospholipases A2, Cytosolic/*metabolism
Prostaglandins/*biosynthesis
Ventromedial Hypothalamic Nucleus/*metabolism
Animals ; Arachidonic Acid/metabolism ; Biosynthetic Pathways ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Gene Knockdown Techniques ; Group IV Phospholipases A2/antagonists & inhibitors ; Group IV Phospholipases A2/genetics ; Group IV Phospholipases A2/metabolism ; Hyperglycemia/metabolism ; Insulin Resistance ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Phospholipases A2, Cytosolic/antagonists & inhibitors ; Phospholipases A2, Cytosolic/genetics ; Phospholipids/metabolism
Czasopismo naukowe
Tytuł :
Scorpion venom phospholipases A 2 : A minireview.
Autorzy :
Krayem N; Laboratoire de Biochimie et de Génie Enzymatique des Lipases, ENIS, Université de Sfax, Route de Soukra 3038, BP 1173, Sfax, Tunisia.
Gargouri Y; Laboratoire de Biochimie et de Génie Enzymatique des Lipases, ENIS, Université de Sfax, Route de Soukra 3038, BP 1173, Sfax, Tunisia. Electronic address: .
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Źródło :
Toxicon : official journal of the International Society on Toxinology [Toxicon] 2020 Sep; Vol. 184, pp. 48-54. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Phospholipases A2, Secretory*
Scorpion Venoms*
Amino Acid Sequence ; Animals ; Bee Venoms ; Bees ; Dimerization ; Phospholipases A2 ; Scorpions ; Snakes
Czasopismo naukowe
Tytuł :
iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4.
Autorzy :
Chen D; Institute for Cancer Genetics, and Department of Pathology and Cell Biology, and Herbert Irving Comprehensive Cancer Center,Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, 10032, USA.
Chu B; Institute for Cancer Genetics, and Department of Pathology and Cell Biology, and Herbert Irving Comprehensive Cancer Center,Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, 10032, USA.
Yang X; Institute for Cancer Genetics, and Department of Pathology and Cell Biology, and Herbert Irving Comprehensive Cancer Center,Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, 10032, USA.
Liu Z; Program for Mathematical Genomics, Departments of Systems Biology and Biomedical Informatics, Columbia University, New York, NY, 10032, USA.
Jin Y; Institute for Cancer Genetics, and Department of Pathology and Cell Biology, and Herbert Irving Comprehensive Cancer Center,Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, 10032, USA.
Kon N; Institute for Cancer Genetics, and Department of Pathology and Cell Biology, and Herbert Irving Comprehensive Cancer Center,Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, 10032, USA.
Rabadan R; Program for Mathematical Genomics, Departments of Systems Biology and Biomedical Informatics, Columbia University, New York, NY, 10032, USA.
Jiang X; Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA.
Stockwell BR; Department of Biological Sciences, Department of Chemistry, Columbia University, New York, NY, 10027, USA.
Gu W; Institute for Cancer Genetics, and Department of Pathology and Cell Biology, and Herbert Irving Comprehensive Cancer Center,Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, 10032, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 15; Vol. 12 (1), pp. 3644. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Ferroptosis/*physiology
Group VI Phospholipases A2/*metabolism
Phospholipid Hydroperoxide Glutathione Peroxidase/*metabolism
Tumor Suppressor Protein p53/*metabolism
A549 Cells ; Animals ; Cell Line, Tumor ; Cell Survival ; Disease Models, Animal ; Fatty Acids/metabolism ; Female ; Ferroptosis/genetics ; Group VI Phospholipases A2/genetics ; Humans ; Mice ; Mice, Nude ; Phospholipid Hydroperoxide Glutathione Peroxidase/genetics ; Phospholipids ; Reactive Oxygen Species/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D.
Autorzy :
Zheng J; Department of Microbiology and Immunology and.
Meyerholz D; Pathology, University of Iowa, Iowa City, Iowa, USA.
Wong LR; Department of Microbiology and Immunology and.
Gelb M; Departments of Chemistry and Biochemistry, University of Washington, Seattle, Washington, USA.
Murakami M; Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Perlman S; Department of Microbiology and Immunology and.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2021 Jun 01; Vol. 131 (11).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antibody Formation*
Antibodies, Viral/*immunology
COVID-19/*immunology
Group II Phospholipases A2/*immunology
Middle East Respiratory Syndrome Coronavirus/*immunology
SARS Virus/*immunology
SARS-CoV-2/*immunology
Severe Acute Respiratory Syndrome/*immunology
Animals ; COVID-19/enzymology ; COVID-19/genetics ; Chlorocebus aethiops ; Group II Phospholipases A2/deficiency ; Mice ; Mice, Knockout ; Severe Acute Respiratory Syndrome/enzymology ; Severe Acute Respiratory Syndrome/genetics ; Vero Cells
Czasopismo naukowe
Tytuł :
Short Linear Motifs Characterizing Snake Venom and Mammalian Phospholipases A2.
Autorzy :
Peggion C; Department of Biomedical Sciences, University of Padova, Via U. Bassi, 58/B, 35131 Padova, Italy.
Tonello F; CNR of Italy, Neuroscience Institute, viale G. Colombo 3, 35131 Padova, Italy.
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Źródło :
Toxins [Toxins (Basel)] 2021 Apr 20; Vol. 13 (4). Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Phospholipases A2/*metabolism
Snake Venoms/*enzymology
Amino Acid Motifs ; Animals ; Binding Sites ; Conserved Sequence ; Models, Molecular ; Phospholipases A2/chemistry ; Protein Binding ; Protein Interaction Domains and Motifs ; Sequence Alignment ; Structure-Activity Relationship ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Insight into Shared Properties and Differential Dynamics and Specificity of Secretory Phospholipase A 2 Family Members.
Autorzy :
Zhang S; Faculty of Environmental and Life Sciences, Beijing University of Technology, Beijing 100124, China.
Gong W; Faculty of Environmental and Life Sciences, Beijing University of Technology, Beijing 100124, China.
Han Z; Faculty of Environmental and Life Sciences, Beijing University of Technology, Beijing 100124, China.
Liu Y; Faculty of Environmental and Life Sciences, Beijing University of Technology, Beijing 100124, China.
Li C; Faculty of Environmental and Life Sciences, Beijing University of Technology, Beijing 100124, China.
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Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2021 Apr 08; Vol. 125 (13), pp. 3353-3363. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Phospholipases A2, Secretory*/genetics
Phospholipases A2, Secretory*/metabolism
Computational Biology ; Family ; Phospholipids ; Signal Transduction
Czasopismo naukowe
Tytuł :
Structural, enzymatic and pharmacological profiles of AplTX-II - A basic sPLA 2 (D49) isolated from the Agkistrodon piscivorus leucostoma snake venom.
Autorzy :
Resende LM; Department of Biochemistry and Tissue Biology, Institute of Biology, Campinas State University (UNICAMP), Campinas, SP, Brazil.
Almeida JR; IKIAM - Universidad Regional Amazonica, Km 7 Via Muyuna, Tena, Napo, Ecuador.
Guaraca-Medina TA; IKIAM - Universidad Regional Amazonica, Km 7 Via Muyuna, Tena, Napo, Ecuador.
Viegas MF; LAQV/Requimte, University of Porto, Rua do Campo Alegre s/n, Porto, Portugal; Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre s/n, Porto, Portugal.
Soares AM; Biotechnology Laboratory for Proteins and Bioactive Compounds from the Western Amazon, Oswaldo Cruz Foundation Rondonia, Porto Velho, Rondonia, Brazil; Oswaldo Cruz Foundation, FIOCRUZ, Rondonia and Federal University of Rondonia, UNIR, Porto Velho, RO, Brazil.
Ramos MJ; LAQV/Requimte, University of Porto, Rua do Campo Alegre s/n, Porto, Portugal; Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre s/n, Porto, Portugal.
Fernandes PA; LAQV/Requimte, University of Porto, Rua do Campo Alegre s/n, Porto, Portugal; Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre s/n, Porto, Portugal.
Marangoni S; Department of Biochemistry and Tissue Biology, Institute of Biology, Campinas State University (UNICAMP), Campinas, SP, Brazil.
Da Silva SL; LAQV/Requimte, University of Porto, Rua do Campo Alegre s/n, Porto, Portugal; Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre s/n, Porto, Portugal; Faculty of Chemical Sciences, University of Cuenca, Cuenca, Azuay, Ecuador. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Apr 01; Vol. 175, pp. 572-585. Date of Electronic Publication: 2021 Jan 30.
Typ publikacji :
Journal Article
MeSH Terms :
Agkistrodon/*metabolism
Phospholipases A2, Secretory/*isolation & purification
Snake Venoms/*chemistry
Agkistrodon/physiology ; Amino Acid Sequence ; Animals ; Crotalid Venoms/enzymology ; Molecular Weight ; Phospholipases A2, Secretory/chemistry ; Phospholipases A2, Secretory/metabolism ; Phospholipids/chemistry ; Snake Venoms/isolation & purification ; Snakes
Czasopismo naukowe
Tytuł :
Bee Venom and Its Sub-Components: Characterization, Pharmacology, and Therapeutics.
Autorzy :
Kim W; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul 02453, Korea.
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Źródło :
Toxins [Toxins (Basel)] 2021 Mar 07; Vol. 13 (3). Date of Electronic Publication: 2021 Mar 07.
Typ publikacji :
Editorial; Introductory Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apamin/*pharmacology
Bee Venoms/*pharmacology
Bees/*metabolism
Melitten/*pharmacology
Phospholipases A2/*pharmacology
Acupuncture Therapy ; Animals ; Apamin/isolation & purification ; Apamin/therapeutic use ; Bee Venoms/chemistry ; Bee Venoms/therapeutic use ; Humans ; Melitten/isolation & purification ; Melitten/therapeutic use ; Phospholipases A2/isolation & purification ; Phospholipases A2/therapeutic use
Czasopismo naukowe
Tytuł :
Protein composition and biochemical characterization of venom from Sonoran Coral Snakes (Micruroides euryxanthus).
Autorzy :
Bénard-Valle M; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad # 2001, Colonia Chamilpa, CP: 62210, Cuernavaca, Morelos, Mexico.
Neri-Castro E; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad # 2001, Colonia Chamilpa, CP: 62210, Cuernavaca, Morelos, Mexico.
Elizalde-Morales N; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad # 2001, Colonia Chamilpa, CP: 62210, Cuernavaca, Morelos, Mexico.
Olvera-Rodríguez A; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad # 2001, Colonia Chamilpa, CP: 62210, Cuernavaca, Morelos, Mexico.
Strickland J; Department of Biological Sciences, Clemson University, Clemson, SC, 29632, USA; Department of Biology, University of South Alabama, Mobile, AL, 36688, USA.
Acosta G; MIVIA. Museo Itinerante de Vida Animal, Hermosillo, Sonora, Mexico.
Alagón A; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad # 2001, Colonia Chamilpa, CP: 62210, Cuernavaca, Morelos, Mexico. Electronic address: .
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Źródło :
Biochimie [Biochimie] 2021 Mar; Vol. 182, pp. 206-216. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article
MeSH Terms :
Coral Snakes*/genetics
Coral Snakes*/metabolism
Elapid Venoms*/biosynthesis
Elapid Venoms*/genetics
Phospholipases A2*/biosynthesis
Phospholipases A2*/genetics
Reptilian Proteins*/biosynthesis
Reptilian Proteins*/genetics
Animals ; Species Specificity
Czasopismo naukowe
Tytuł :
Factors influencing the antioxidant effect of phospholipase A2 against lipid oxidation promoted by trout hemoglobin and hemin in washed muscle.
Autorzy :
Tatiyaborworntham N; Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Meat Science and Animal Biologics Discovery Building, 1933 Observatory Dr. Madison, Wisconsin 53706, United States. Electronic address: .
Yin J; Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Meat Science and Animal Biologics Discovery Building, 1933 Observatory Dr. Madison, Wisconsin 53706, United States.
Richards MP; Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Meat Science and Animal Biologics Discovery Building, 1933 Observatory Dr. Madison, Wisconsin 53706, United States. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 May 01; Vol. 343, pp. 128428. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
MeSH Terms :
Hemin/*metabolism
Hemoglobins/*metabolism
Phospholipases A2/*chemistry
Trout/*metabolism
Animals ; Antioxidants/metabolism ; Fish Products ; Fish Proteins/chemistry ; Fish Proteins/metabolism ; Hemin/chemistry ; Hemoglobins/chemistry ; Hydrogen-Ion Concentration ; Lipid Metabolism ; Muscle, Skeletal/metabolism ; Oxidation-Reduction ; Phospholipases A2/metabolism ; Swine
Czasopismo naukowe
Tytuł :
Bis(µ-Tartrato)Di(μ-Hydroxy) Germanate (IV) Triethanolammonium as a Mononuclear Alkaline Phospholipase A 2 Inhibitor.
Autorzy :
Storozhenko PA; Institute of Chemistry and Technology of Organoelement Compounds, Moscow, Russia.
Rasulov MM; Institute of Chemistry and Technology of Organoelement Compounds, Moscow, Russia. .
Zhigacheva IV; Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia.
Baryshok VP; Irkutsk State Technical University, Irkutsk, Russia.
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Źródło :
Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2021 May; Vol. 496 (1), pp. 10-13. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Ethanolamines/*pharmacology
Hyperlipidemias/*drug therapy
Organometallic Compounds/*pharmacology
Phospholipase A2 Inhibitors/*pharmacology
Phospholipases A2/*metabolism
Animals ; Cholesterol/blood ; Germanium/chemistry ; Germanium/pharmacology ; Hyperlipidemias/enzymology ; Hyperlipidemias/pathology ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/enzymology ; Lipid Metabolism/drug effects ; Lipids/blood ; Phospholipases A2/blood ; Rabbits
Czasopismo naukowe
Tytuł :
Phospholipase iPLA 2 β averts ferroptosis by eliminating a redox lipid death signal.
Autorzy :
Sun WY; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA.; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MoE), College of Pharmacy, Jinan University, Guangzhou, China.
Tyurin VA; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA.
Mikulska-Ruminska K; Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Toruń, Toruń, Poland.; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Shrivastava IH; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Anthonymuthu TS; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Critical Care Medicine, Safar Center for Resuscitation Research, Children's Neuroscience Institute, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, USA.
Zhai YJ; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MoE), College of Pharmacy, Jinan University, Guangzhou, China.
Pan MH; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MoE), College of Pharmacy, Jinan University, Guangzhou, China.
Gong HB; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MoE), College of Pharmacy, Jinan University, Guangzhou, China.
Lu DH; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MoE), College of Pharmacy, Jinan University, Guangzhou, China.
Sun J; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MoE), College of Pharmacy, Jinan University, Guangzhou, China.
Duan WJ; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MoE), College of Pharmacy, Jinan University, Guangzhou, China.
Korolev S; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Abramov AY; UCL Queen Square Institute of Neurology, Department of Clinical and Movement Neurosciences, University College London, Queen Square, London, UK.
Angelova PR; UCL Queen Square Institute of Neurology, Department of Clinical and Movement Neurosciences, University College London, Queen Square, London, UK.
Miller I; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Beharier O; Magee-Womens Research Institute and Department of OBGYN, University of Pittsburgh, Pittsburgh, PA, USA.
Mao GW; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA.
Dar HH; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA.
Kapralov AA; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA.
Amoscato AA; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA.
Hastings TG; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
Greenamyre TJ; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
Chu CT; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
Sadovsky Y; Magee-Womens Research Institute and Department of OBGYN, University of Pittsburgh, Pittsburgh, PA, USA.
Bahar I; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Bayır H; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Critical Care Medicine, Safar Center for Resuscitation Research, Children's Neuroscience Institute, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, USA.
Tyurina YY; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA. .
He RR; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou, China. .; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MoE), College of Pharmacy, Jinan University, Guangzhou, China. .
Kagan VE; Department of Environmental and Occupational Health and Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA. .; Department of Radiation Oncology, University of Pittsburgh, Pittsburgh, PA, USA. .; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA. .; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA. .; Institute of Regenerative Medicine, IM Sechenov Moscow State Medical University, Moscow, Russia. .
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Źródło :
Nature chemical biology [Nat Chem Biol] 2021 Apr; Vol. 17 (4), pp. 465-476. Date of Electronic Publication: 2021 Feb 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ferroptosis/*physiology
Group VI Phospholipases A2/*metabolism
Animals ; Arachidonate 15-Lipoxygenase/metabolism ; Disease Models, Animal ; Female ; Group VI Phospholipases A2/physiology ; Humans ; Iron/metabolism ; Leukotrienes/metabolism ; Lipid Metabolism/physiology ; Lipid Peroxides/metabolism ; Lipids/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Oxidation-Reduction ; Parkinson Disease/metabolism ; Phosphatidylethanolamine Binding Protein/metabolism ; Phospholipases/metabolism ; Phospholipids/metabolism ; Rats ; Rats, Inbred Lew
Czasopismo naukowe
Tytuł :
Secretory Phospholipase A 2 Inhibition Attenuates Adhesive Properties of Esophageal Barrett's Cells.
Autorzy :
Gergen AK; University of Colorado School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Aurora, Colorado. Electronic address: .
Jarrett MJ; University of Colorado School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Aurora, Colorado.
Li A; University of Colorado School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Aurora, Colorado.
White AM; University of Colorado School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Aurora, Colorado.
Meng X; University of Colorado School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Aurora, Colorado.
Fullerton DA; University of Colorado School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Aurora, Colorado.
Weyant MJ; University of Colorado School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Aurora, Colorado.
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Źródło :
The Journal of surgical research [J Surg Res] 2021 Mar; Vol. 259, pp. 562-568. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Barrett Esophagus/*pathology
Esophagus/*pathology
Group II Phospholipases A2/*antagonists & inhibitors
Pentanoic Acids/*pharmacology
Adenocarcinoma/pathology ; Adenocarcinoma/prevention & control ; Barrett Esophagus/drug therapy ; Cell Adhesion/drug effects ; Cell Line ; Cell Proliferation/drug effects ; Drug Evaluation, Preclinical ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/prevention & control ; Esophagus/cytology ; Group II Phospholipases A2/metabolism ; Humans ; Pentanoic Acids/therapeutic use
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
Secreted Phospholipase A 2 Group X Acts as an Adjuvant for Type 2 Inflammation, Leading to an Allergen-Specific Immune Response in the Lung.
Autorzy :
Ogden HL; Division of Pulmonary, Critical Care and Sleep, Department of Medicine, University of Washington, Seattle, WA 98109.
Lai Y; Division of Pulmonary, Critical Care and Sleep, Department of Medicine, University of Washington, Seattle, WA 98109.
Nolin JD; Division of Pulmonary, Critical Care and Sleep, Department of Medicine, University of Washington, Seattle, WA 98109.
An D; Division of Pulmonary, Critical Care and Sleep, Department of Medicine, University of Washington, Seattle, WA 98109.
Frevert CW; Division of Pulmonary, Critical Care and Sleep, Department of Medicine, University of Washington, Seattle, WA 98109.; Department of Comparative Medicine, University of Washington, Seattle, WA 98109.
Gelb MH; Department of Chemistry, University of Washington, Seattle, WA 98195; and.; Department of Biochemistry, University of Washington, Seattle, WA 98195.
Altemeier WA; Division of Pulmonary, Critical Care and Sleep, Department of Medicine, University of Washington, Seattle, WA 98109.
Hallstrand TS; Division of Pulmonary, Critical Care and Sleep, Department of Medicine, University of Washington, Seattle, WA 98109; .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Jun 15; Vol. 204 (12), pp. 3097-3107. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Adaptive Immunity/*immunology
Allergens/*immunology
Group X Phospholipases A2/*immunology
Inflammation/*immunology
Lung/*immunology
Animals ; Antigens/immunology ; Asthma/immunology ; Bee Venoms/immunology ; Cytokines/immunology ; Female ; Mice ; Mice, Inbred BALB C ; Phospholipases A2/immunology
Czasopismo naukowe
Tytuł :
In silico and in vitro neutralization of PLA 2 activity of Daboxin P by butein, mimosine and bakuchiol.
Autorzy :
Devi A; Molecular Toxinology Laboratory, Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur 784028, Assam, India.
Namsa ND; Molecular Virology Laboratory, Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur 784028, Assam, India.
Doley R; Molecular Toxinology Laboratory, Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur 784028, Assam, India. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 15; Vol. 165 (Pt A), pp. 1066-1078. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Journal Article
MeSH Terms :
Phospholipase A2 Inhibitors/*isolation & purification
Phospholipases A2/*chemistry
Plants, Medicinal/*chemistry
Snake Bites/*drug therapy
Animals ; Computer Simulation ; Humans ; Molecular Docking Simulation ; Phospholipase A2 Inhibitors/chemistry ; Phospholipase A2 Inhibitors/metabolism ; Phospholipases A2/drug effects ; Phospholipases A2/genetics ; Secondary Metabolism/genetics ; Snake Bites/genetics ; Snake Venoms/antagonists & inhibitors ; Snake Venoms/chemistry
Czasopismo naukowe
Tytuł :
Eicosanoid Signaling in Insect Immunology: New Genes and Unresolved Issues.
Autorzy :
Kim Y; Department of Plant Medicals, College of Life Sciences, Andong National University, Andong 36729, Korea.
Stanley D; Biological Control of Insects Research Laboratory, USDA/Agricultural Research Service, 1503 South Providence Road, Columbia, MO 65203, USA.
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Źródło :
Genes [Genes (Basel)] 2021 Feb 01; Vol. 12 (2). Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Eicosanoids/*genetics
Insecta/*genetics
Phospholipases A2/*genetics
Signal Transduction/*genetics
Animals ; Arachidonic Acid/genetics ; Arachidonic Acid/immunology ; Eicosanoids/biosynthesis ; Eicosanoids/immunology ; Fatty Acid Desaturases/genetics ; Fatty Acid Desaturases/immunology ; Hemocytes/enzymology ; Insecta/immunology ; Insecta/metabolism ; Lipoxygenase/genetics ; Lipoxygenase/immunology ; Mammals/genetics ; Mammals/immunology ; Phospholipases A2/immunology ; Platelet Activating Factor/analogs & derivatives ; Platelet Activating Factor/genetics ; Platelet Activating Factor/immunology ; Prostaglandin-Endoperoxide Synthases/genetics
Czasopismo naukowe
Tytuł :
Extracellular Acidity-mediated Expression of cPLA2γ Confers Resistance in Gastric Cancer Cells.
Autorzy :
Lim SC; Department of Pathology, College of Medicine, Chosun University, Gwangju, Republic of Korea.
Lee TB; Division of Premedical Science, College of Medicine, Chosun University, Gwangju, Republic of Korea.
Kang BS; Department of Pathology, College of Medicine, Chosun University, Gwangju, Republic of Korea.
Iy Han S; Division of Premedical Science, College of Medicine, Chosun University, Gwangju, Republic of Korea .
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Źródło :
Anticancer research [Anticancer Res] 2021 Jan; Vol. 41 (1), pp. 211-218.
Typ publikacji :
Journal Article
MeSH Terms :
Hydrogen-Ion Concentration*
Drug Resistance, Neoplasm/*genetics
Group IV Phospholipases A2/*genetics
Stomach Neoplasms/*genetics
Stomach Neoplasms/*metabolism
Antineoplastic Agents/pharmacology ; Caspase 3/metabolism ; Cell Line, Tumor ; Extracellular Space/metabolism ; Gene Expression ; Gene Silencing ; Group IV Phospholipases A2/metabolism ; Humans ; RNA, Small Interfering ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Disrupting a phospholipase A 2 gene increasing lipid accumulation in the oleaginous yeast Yarrowia lipolytica.
Autorzy :
Li JX; Shandong Provincial Key Laboratory of Synthetic Biology, Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.; University of Chinese Academy of Sciences, Beijing, China.
Xu J; Shandong Provincial Key Laboratory of Synthetic Biology, Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.; Department of Environmental Science and Engineering, Qingdao University, Qingdao, Shandong, China.
Ruan JC; Zhejiang Zhenyuan Share Co., Ltd, Hangzhou, China.
Meng HM; Shandong Provincial Key Laboratory of Synthetic Biology, Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.
Su H; Shandong Provincial Key Laboratory of Synthetic Biology, Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.
Han XF; Shandong Provincial Key Laboratory of Synthetic Biology, Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.
Lu M; Shandong Provincial Key Laboratory of Synthetic Biology, Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.
Li FL; Shandong Provincial Key Laboratory of Synthetic Biology, Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.
Wang SA; Shandong Provincial Key Laboratory of Synthetic Biology, Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.
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Źródło :
Journal of applied microbiology [J Appl Microbiol] 2021 Jan; Vol. 130 (1), pp. 100-108. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Lipid Metabolism*/genetics
Fungal Proteins/*genetics
Phospholipases A2/*genetics
Yarrowia/*metabolism
Biofuels/microbiology ; Bioreactors ; Fermentation ; Lipids/biosynthesis ; Metabolic Engineering ; Mutation ; Phospholipases A2/deficiency ; Yarrowia/enzymology ; Yarrowia/genetics
Czasopismo naukowe
Tytuł :
Compound heterozygous PLA2G6 loss-of-function variants in Swaledale sheep with neuroaxonal dystrophy.
Autorzy :
Letko A; Institute of Genetics, Vetsuisse Faculty, University of Bern, 3001, Bern, Switzerland.
Strugnell B; Farm Post Mortems Ltd, Hamsterley House, Hamsterley, Bishop Auckland, Durham, DL13 3QF, UK.
Häfliger IM; Institute of Genetics, Vetsuisse Faculty, University of Bern, 3001, Bern, Switzerland.
Paris JM; Institute of Genetics, Vetsuisse Faculty, University of Bern, 3001, Bern, Switzerland.
Waine K; University of Nottingham, College Road, Sutton Bonington, Loughborough, LE12 5RD, UK.
Drögemüller C; Institute of Genetics, Vetsuisse Faculty, University of Bern, 3001, Bern, Switzerland. .
Scholes S; SRUC Consulting Veterinary Services, Pentlands Science Park, Bush Estate Loan, Penicuik, Midlothian, EH26 0PZ, UK.
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Źródło :
Molecular genetics and genomics : MGG [Mol Genet Genomics] 2021 Jan; Vol. 296 (1), pp. 235-242. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article
MeSH Terms :
Polymorphism, Single Nucleotide*
Amyloid beta-Protein Precursor/*genetics
Group VI Phospholipases A2/*genetics
Neuroaxonal Dystrophies/*genetics
Neuroaxonal Dystrophies/*veterinary
Sheep Diseases/*genetics
Alternative Splicing ; Amyloid beta-Protein Precursor/metabolism ; Animals ; Base Sequence ; Chromosome Mapping ; Chromosomes, Mammalian/chemistry ; Exons ; Female ; Gene Expression ; Genetic Linkage ; Group VI Phospholipases A2/deficiency ; Heterozygote ; Introns ; Male ; Neuroaxonal Dystrophies/metabolism ; Neuroaxonal Dystrophies/pathology ; Sheep ; Sheep Diseases/metabolism ; Sheep Diseases/pathology ; Sheep, Domestic ; Whole Genome Sequencing
Czasopismo naukowe

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