Temat: "Phospholipases A2, Cytosolic" - OpacWWW

Skocz do pozycji: 1 1.

Tytuł :: PARP inhibition in vivo blocks alcohol-induced brain neurodegeneration and neuroinflammatory cytosolic phospholipase A2 elevations.
Autorzy :: Kouzoukas DE; Department of Molecular Pharmacology & Therapeutics, Loyola University Chicago, Maywood, IL, USA; Alcohol Research Program, Loyola University Chicago, Maywood, IL, USA; Research Service, Edward Hines Jr. VA Hospital, Hines, IL, USA. Electronic address: .
Schreiber JA; Neuroscience Graduate Program, Loyola University Chicago, Maywood, IL, USA; Alcohol Research Program, Loyola University Chicago, Maywood, IL, USA.
Tajuddin NF; Department of Molecular Pharmacology & Therapeutics, Loyola University Chicago, Maywood, IL, USA.
Kaja S; Department of Molecular Pharmacology & Therapeutics, Loyola University Chicago, Maywood, IL, USA; Neuroscience Graduate Program, Loyola University Chicago, Maywood, IL, USA; Department of Ophthalmology, Loyola University Chicago, Maywood, IL, USA; Alcohol Research Program, Loyola University Chicago, Maywood, IL, USA; Burn Shock Trauma Research Institute, Loyola University Chicago, Maywood, IL, USA; Research Service, Edward Hines Jr. VA Hospital, Hines, IL, USA.
Neafsey EJ; Department of Molecular Pharmacology & Therapeutics, Loyola University Chicago, Maywood, IL, USA.
Kim HY; Laboratory of Molecular Signaling, National Institute of Alcoholism and Alcohol Abuse, National Institutes of Health, Bethesda, MD, USA.
Collins MA; Department of Molecular Pharmacology & Therapeutics, Loyola University Chicago, Maywood, IL, USA; Neuroscience Graduate Program, Loyola University Chicago, Maywood, IL, USA; Alcohol Research Program, Loyola University Chicago, Maywood, IL, USA.; Pokaż więcej
Źródło :: Neurochemistry international [Neurochem Int] 2019 Oct; Vol. 129, pp. 104497. Date of Electronic Publication: 2019 Jun 25.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :: Alcohol-Induced Disorders, Nervous System/*prevention & control
Benzimidazoles/*therapeutic use
Nerve Tissue Proteins/*biosynthesis
Phospholipases A2, Cytosolic/*biosynthesis
Poly(ADP-ribose) Polymerase Inhibitors/*therapeutic use
Alcohol-Induced Disorders, Nervous System/drug therapy ; Alcohol-Induced Disorders, Nervous System/enzymology ; Animals ; Benzimidazoles/pharmacology ; Binge Drinking ; Dentate Gyrus/drug effects ; Dentate Gyrus/enzymology ; Dentate Gyrus/pathology ; Disease Models, Animal ; Entorhinal Cortex/drug effects ; Entorhinal Cortex/enzymology ; Entorhinal Cortex/pathology ; Enzyme Induction/drug effects ; Male ; Nerve Tissue Proteins/genetics ; Phospholipases A2, Cytosolic/genetics ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Rats ; Rats, Sprague-Dawley
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia.
Autorzy :: Chang JF; Division of Nephrology, Department of Internal Medicine, En Chu Kong Hospital, New Taipei City 237, Taiwan. .; Renal Care Joint Foundation, New Taipei City 220, Taiwan. .; Department of Nursing, Yuanpei University of Medical Technology, Hsinchu 300, Taiwan. .; Graduate Institution of Biomedical and Pharmaceutical Science, College of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan. .; Division of Nephrology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City 235, Taiwan. .
Yeh JC; Renal Care Joint Foundation, New Taipei City 220, Taiwan. .; Department of Dentistry, Far Eastern Memorial Hospital, New Taipei City 220, Taiwan. .
Ho CT; Renal Care Joint Foundation, New Taipei City 220, Taiwan. .
Liu SH; Division of Pathology, En-Chu-Kong Hospital, New Taipei City 237, Taiwan. .
Hsieh CY; Division of Nephrology, Department of Internal Medicine, En Chu Kong Hospital, New Taipei City 237, Taiwan. .; Renal Care Joint Foundation, New Taipei City 220, Taiwan. .
Wang TM; Department of Orthopaedic Surgery, School of Medicine, National Taiwan University, Taipei 106, Taiwan. .; Department of Orthopaedic Surgery, National Taiwan University Hospital, Taipei 106, Taiwan. .
Chang SW; Department of Civil Engineering, National Taiwan University, Taipei 106, Taiwan. .
Lee IT; School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan. .
Huang KY; Graduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei 114, Taiwan. .
Wang JY; Graduate Institution of Biomedical and Pharmaceutical Science, College of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan. .
Lin WN; Graduate Institution of Biomedical and Pharmaceutical Science, College of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan. .; Pokaż więcej
Źródło :: International journal of molecular sciences [Int J Mol Sci] 2019 Sep 06; Vol. 20 (18). Date of Electronic Publication: 2019 Sep 06.
Typ publikacji :: Journal Article
MeSH Terms :: Cyclooxygenase 2/*genetics
Endotoxemia/*complications
Kidney Diseases/*etiology
Kidney Diseases/*metabolism
Obesity/*complications
Phospholipases A2, Cytosolic/*genetics
Reactive Oxygen Species/*metabolism
Animals ; Biomarkers ; Cyclooxygenase 2/metabolism ; Disease Models, Animal ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Fibrosis ; Gene Expression Regulation/drug effects ; Immunohistochemistry ; Kidney Diseases/drug therapy ; Kidney Diseases/pathology ; Lipid Metabolism ; Lymphocytes/immunology ; Lymphocytes/metabolism ; Mice ; Molecular Targeted Therapy ; Oxidative Stress ; Phospholipases A2, Cytosolic/metabolism ; Signal Transduction/drug effects
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 3 3.

Tytuł :: Expression of Cytosolic Phospholipase A2 (cPLA2)-Arachidonic Acid (AA)-Cyclooxygenase-2 (COX-2) Pathway Factors in Lung Cancer Patients and Its Implication in Lung Cancer Early Detection and Prognosis.
Autorzy :: Xin C; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Chu L; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Zhang L; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Geng D; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Wang Y; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Sun D; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Sui P; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Zhao X; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Gong Z; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Sui M; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).
Zhang W; Department of Medical Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China (mainland).; Pokaż więcej
Źródło :: Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2019 Jul 26; Vol. 25, pp. 5543-5551. Date of Electronic Publication: 2019 Jul 26.
Typ publikacji :: Journal Article
MeSH Terms :: Arachidonic Acid/*metabolism
Cyclooxygenase 2/*metabolism
Lung Neoplasms/*metabolism
Phospholipases A2, Cytosolic/*metabolism
Adult ; Aged ; Arachidonic Acid/blood ; Arachidonic Acid/genetics ; Cyclooxygenase 2/blood ; Cyclooxygenase 2/genetics ; Cytosol/metabolism ; Dinoprostone/metabolism ; Early Detection of Cancer/methods ; Female ; Humans ; Intramolecular Oxidoreductases/metabolism ; Isoenzymes ; Lung/metabolism ; Lung Neoplasms/genetics ; Male ; Middle Aged ; Phospholipases A2, Cytosolic/blood ; Phospholipases A2, Cytosolic/genetics ; Prognosis ; Prostaglandin-E Synthases/genetics ; Prostaglandin-E Synthases/metabolism ; RNA, Messenger/metabolism ; Signal Transduction/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: cPLA2 activation contributes to lysosomal defects leading to impairment of autophagy after spinal cord injury.
Autorzy :: Li Y; Department of Anesthesiology & Center for Shock, Trauma and Anesthesiology Research (STAR), School of Medicine, University of Maryland, Baltimore, MD, USA.
Jones JW; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD, USA.
M C Choi H; Department of Anesthesiology & Center for Shock, Trauma and Anesthesiology Research (STAR), School of Medicine, University of Maryland, Baltimore, MD, USA.
Sarkar C; Department of Anesthesiology & Center for Shock, Trauma and Anesthesiology Research (STAR), School of Medicine, University of Maryland, Baltimore, MD, USA.
Kane MA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD, USA.
Koh EY; Department of Orthopedics, School of Medicine, University of Maryland, Baltimore, MD, USA.
Lipinski MM; Department of Anesthesiology & Center for Shock, Trauma and Anesthesiology Research (STAR), School of Medicine, University of Maryland, Baltimore, MD, USA. .
Wu J; Department of Anesthesiology & Center for Shock, Trauma and Anesthesiology Research (STAR), School of Medicine, University of Maryland, Baltimore, MD, USA. .; Pokaż więcej
Źródło :: Cell death & disease [Cell Death Dis] 2019 Jul 11; Vol. 10 (7), pp. 531. Date of Electronic Publication: 2019 Jul 11.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Autophagy*/drug effects
Autophagy*/genetics
Lysosomes/*metabolism
Phospholipases A2, Cytosolic/*metabolism
Phospholipids/*chemistry
Spinal Cord Injuries/*metabolism
Spinal Cord Injuries/*physiopathology
Animals ; Autophagosomes/drug effects ; Autophagosomes/metabolism ; Cathepsin D/genetics ; Cathepsin D/metabolism ; Cell Death/drug effects ; Cell Death/genetics ; Lysosomal-Associated Membrane Protein 2/metabolism ; Lysosomes/drug effects ; Lysosomes/enzymology ; Lysosomes/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/drug effects ; Neurons/enzymology ; Neurons/metabolism ; Phospholipases A2, Cytosolic/antagonists & inhibitors ; Phospholipases A2, Cytosolic/genetics ; Phospholipids/metabolism ; Sequestosome-1 Protein/genetics ; Sequestosome-1 Protein/metabolism ; Spinal Cord/pathology ; Spinal Cord Injuries/genetics ; alpha-N-Acetylgalactosaminidase/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior.
Autorzy :: Venturini V; ICFO - Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels, Spain.; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.
Pezzano F; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.
Català Castro F; ICFO - Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels, Spain.
Häkkinen HM; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.
Jiménez-Delgado S; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.
Colomer-Rosell M; ICFO - Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels, Spain.
Marro M; ICFO - Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels, Spain.
Tolosa-Ramon Q; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.
Paz-López S; Laboratory of Molecular Physiology, Department of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Valverde MA; Laboratory of Molecular Physiology, Department of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Weghuber J; School of Engineering, University of Applied Sciences Upper Austria, Stelzhamerstraße 23, Wels 4600, Austria.
Loza-Alvarez P; ICFO - Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels, Spain.
Krieg M; ICFO - Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels, Spain.
Wieser S; ICFO - Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels, Spain. .
Ruprecht V; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 08003 Barcelona, Spain. .; Department of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Pokaż więcej
Źródło :: Science (New York, N.Y.) [Science] 2020 Oct 16; Vol. 370 (6514).
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Cell Shape*
Mechanotransduction, Cellular*
Nuclear Envelope/*physiology
Phospholipases A2, Cytosolic/*metabolism
Actomyosin/metabolism ; Animals ; Cell Movement ; Lipase/metabolism ; Myosin Type II/metabolism ; Zebrafish
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 6 6.

Tytuł :: Cytosolic Phospholipase A 2 Facilitates Oligomeric Amyloid-β Peptide Association with Microglia via Regulation of Membrane-Cytoskeleton Connectivity.
Autorzy :: Teng T; Department of Bioengineering, University of Illinois at Chicago, 835 S Wolcott Ave, W100, Chicago, IL, 60612, USA.
Dong L; Department of Bioengineering, University of Missouri, Columbia, MO, 65211, USA.
Ridgley DM; Department of Bioengineering, University of Illinois at Chicago, 835 S Wolcott Ave, W100, Chicago, IL, 60612, USA.
Ghura S; Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Tobin MK; Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Sun GY; Department of Biochemistry, University of Missouri, Columbia, MO, 65211, USA.
LaDu MJ; Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Lee JC; Department of Bioengineering, University of Illinois at Chicago, 835 S Wolcott Ave, W100, Chicago, IL, 60612, USA. .; Pokaż więcej
Źródło :: Molecular neurobiology [Mol Neurobiol] 2019 May; Vol. 56 (5), pp. 3222-3234. Date of Electronic Publication: 2018 Aug 15.
Typ publikacji :: Journal Article
MeSH Terms :: Protein Multimerization*
Amyloid beta-Peptides/*metabolism
Cell Membrane/*metabolism
Cytoskeleton/*metabolism
Microglia/*metabolism
Phospholipases A2, Cytosolic/*metabolism
Animals ; Cell Membrane/drug effects ; Cells, Cultured ; Cytoskeleton/drug effects ; Enzyme Activation/drug effects ; Humans ; Interferon-gamma/pharmacology ; Kinetics ; Lipopolysaccharides/pharmacology ; Mice ; Phospholipases A2, Cytosolic/antagonists & inhibitors ; Rats
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 7 7.

Tytuł :: The effects of sulfite on cPLA 2 , caspase-3, oxidative stress and locomotor activity in rats.
Autorzy :: Basaranlar G; Akdeniz University, Medical School, Department of Biophysics, Antalya, Turkey.
Derin N; Akdeniz University, Medical School, Department of Biophysics, Antalya, Turkey. Electronic address: .
Kencebay Manas C; Akdeniz University, Medical School, Department of Biophysics, Antalya, Turkey.
Tanriover G; Akdeniz University, Medical School, Department of Histology and Embryology, Antalya, Turkey.
Aslan M; Akdeniz University, Medical School, Department of Biochemistry, Antalya, Turkey.; Pokaż więcej
Źródło :: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2019 Jan; Vol. 123, pp. 453-458. Date of Electronic Publication: 2018 Nov 15.
Typ publikacji :: Journal Article
MeSH Terms :: Caspase 3/*metabolism
Food Preservatives/*toxicity
Locomotion/*drug effects
Oxidative Stress/*drug effects
Phospholipases A2, Cytosolic/*metabolism
Sulfites/*toxicity
Animals ; Behavior, Animal/drug effects ; Caspase 3/genetics ; Food Preservatives/metabolism ; Hippocampus/drug effects ; Hippocampus/enzymology ; Male ; Phospholipases A2, Cytosolic/genetics ; Rats ; Rats, Wistar ; Sulfites/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: Sevoflurane attenuates ventilator‑induced lung injury by regulating c‑PLA2 expression.
Autorzy :: Yang Y; Experimental Center of Medical Function, Kunming Medical University, Kunming, Yunnan 650031, P.R. China.
Wang WF; Department of Anesthesiology, The People's Hospital of Chuxiong Yi Autonomous Prefecture, Chuxiong, Yunnan 675000, P.R. China.
Li YH; Department of Anesthesiology, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650032, P.R. China.
Li LS; Department of Anesthesiology, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650032, P.R. China.
Guo X; Department of Anesthesiology, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650032, P.R. China.
Liu R; Department of Anesthesiology, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650032, P.R. China.; Pokaż więcej
Źródło :: Molecular medicine reports [Mol Med Rep] 2018 Sep; Vol. 18 (3), pp. 2923-2928. Date of Electronic Publication: 2018 Jul 03.
Typ publikacji :: Journal Article
MeSH Terms :: Anti-Inflammatory Agents/*pharmacology
Gene Expression Regulation/*drug effects
Methyl Ethers/*pharmacology
Phospholipases A2, Cytosolic/*genetics
Ventilator-Induced Lung Injury/*genetics
Animals ; Arachidonic Acid/metabolism ; Biopsy ; Disease Models, Animal ; Female ; Lung/drug effects ; Lung/metabolism ; Lung/pathology ; Male ; Phospholipases A2, Cytosolic/metabolism ; Rabbits ; Sevoflurane ; Uteroglobin/genetics ; Uteroglobin/metabolism ; Ventilator-Induced Lung Injury/drug therapy ; Ventilator-Induced Lung Injury/metabolism ; Ventilator-Induced Lung Injury/pathology
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 9 9.

Tytuł :: Cytosolic phospholipase A 2 and F 2 isoprostanes are involved in semen quality and human infertility-A study on leucocytospermia, varicocele and idiopathic infertility.
Autorzy :: Collodel G; Department of Molecular and Developmental Medicine, Policlinico Le Scotte, University of Siena, Siena, Italy.
Castellini C; Department of Agricultural, Food and Environmental Sciences, University of Perugia, Perugia, Italy.
Iacoponi F; Department of Food Safety, Nutrition and Veterinary Public Health, National Institute of Health, Rome, Italy.
Noto D; Department of Molecular and Developmental Medicine, Policlinico Le Scotte, University of Siena, Siena, Italy.
Signorini C; Department of Molecular and Developmental Medicine, Policlinico Le Scotte, University of Siena, Siena, Italy.; Pokaż więcej
Źródło :: Andrologia [Andrologia] 2020 Mar; Vol. 52 (2), pp. e13465. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :: Journal Article
MeSH Terms :: Semen Analysis*
F2-Isoprostanes/*metabolism
Infertility, Male/*enzymology
Phospholipases A2, Cytosolic/*metabolism
Varicocele/*enzymology
Adult ; Case-Control Studies ; Humans ; Male
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: Computational Exploration of Natural Compounds to Target Cytosolic Phospholipase A 2 Protein: A Novel Therapeutic Target for Spinal Cord Injury.
Autorzy :: Fan H; Department of Orthopedics, China-Japan Union Hospital of Jilin University 130033, Changchun, China.
Wang S; Department of Orthopedics, China-Japan Union Hospital of Jilin University 130033, Changchun, China.
Zhao Q; Department of Orthopedics, China-Japan Union Hospital of Jilin University 130033, Changchun, China.
Qin Z; Department of Neurosurgery, China-Japan Union Hospital of Jilin University 130033, Changchun, China.; Pokaż więcej
Źródło :: Current computer-aided drug design [Curr Comput Aided Drug Des] 2018; Vol. 14 (2), pp. 117-124.
Typ publikacji :: Journal Article
MeSH Terms :: Computer-Aided Design*
Drug Design*
Enzyme Inhibitors/*chemistry
Enzyme Inhibitors/*pharmacology
Phospholipases A2, Cytosolic/*antagonists & inhibitors
Spinal Cord Injuries/*drug therapy
Cell Line ; Humans ; Molecular Docking Simulation ; Molecular Targeted Therapy/methods ; Phospholipases A2, Cytosolic/chemistry ; Phospholipases A2, Cytosolic/metabolism ; Spinal Cord Injuries/enzymology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 11 11.

Tytuł :: Effects of Acetylcholine on β-Amyloid-Induced cPLA2 Activation in the TB Neuroectodermal Cell Line: Implications for the Pathogenesis of Alzheimer's Disease.
Autorzy :: Polverino A; Department of Motor Sciences and Wellness, University of Naples Parthenope, Via Medina, 40, 80133, Naples, NA, Italy.; Institute of Diagnosis and Treatment Hermitage, Via Cupa delle Tozzole, 2, 80131, Naples, NA, Italy.
Grimaldi M; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Salerno, SA, Italy.
Sorrentino P; Department of Engineering, University of Naples Parthenope, Centro Direzionale di Napoli, isola C4, 80143, Naples, NA, Italy.
Jacini F; Department of Motor Sciences and Wellness, University of Naples Parthenope, Via Medina, 40, 80133, Naples, NA, Italy.
D'Ursi AM; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Salerno, SA, Italy.
Sorrentino G; Department of Motor Sciences and Wellness, University of Naples Parthenope, Via Medina, 40, 80133, Naples, NA, Italy. .; Institute of Diagnosis and Treatment Hermitage, Via Cupa delle Tozzole, 2, 80131, Naples, NA, Italy. .; Pokaż więcej
Źródło :: Cellular and molecular neurobiology [Cell Mol Neurobiol] 2018 May; Vol. 38 (4), pp. 817-826. Date of Electronic Publication: 2017 Oct 09.
Typ publikacji :: Journal Article
MeSH Terms :: Acetylcholine/*pharmacology
Alzheimer Disease/*metabolism
Amyloid beta-Peptides/*metabolism
Neurons/*drug effects
Phospholipases A2, Cytosolic/*drug effects
Alzheimer Disease/pathology ; Cell Differentiation/drug effects ; Cell Line ; Humans ; Neurons/metabolism ; Neuroprotective Agents/pharmacology ; Phospholipases A2, Cytosolic/metabolism ; Phosphorylation ; Signal Transduction/drug effects
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 12 12.

Tytuł :: Membrane Allostery and Unique Hydrophobic Sites Promote Enzyme Substrate Specificity.
Autorzy :: Mouchlis VD; Department of Chemistry and Biochemistry and Department of Pharmacology, School of Medicine , University of California , San Diego, La Jolla , California 92093-0601 , United States.
Chen Y; Department of Chemistry and Biochemistry and Department of Pharmacology, School of Medicine , University of California , San Diego, La Jolla , California 92093-0601 , United States.
McCammon JA; Department of Chemistry and Biochemistry and Department of Pharmacology, School of Medicine , University of California , San Diego, La Jolla , California 92093-0601 , United States.
Dennis EA; Department of Chemistry and Biochemistry and Department of Pharmacology, School of Medicine , University of California , San Diego, La Jolla , California 92093-0601 , United States.; Pokaż więcej
Źródło :: Journal of the American Chemical Society [J Am Chem Soc] 2018 Mar 07; Vol. 140 (9), pp. 3285-3291. Date of Electronic Publication: 2018 Feb 26.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :: Phospholipases A2, Calcium-Independent/*metabolism
Phospholipases A2, Cytosolic/*metabolism
Phospholipases A2, Secretory/*metabolism
Phospholipids/*metabolism
Binding Sites ; Catalytic Domain ; Humans ; Hydrolysis ; Hydrophobic and Hydrophilic Interactions ; Molecular Dynamics Simulation ; Phospholipases A2, Calcium-Independent/chemistry ; Phospholipases A2, Cytosolic/chemistry ; Phospholipases A2, Secretory/chemistry ; Phospholipids/chemistry ; Substrate Specificity
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A 2 Proves Renal Origins of Urinary PGI-M and TX-M.
Autorzy :: Mitchell JA; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Knowles RB; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Kirkby NS; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Reed DM; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Edin ML; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
White WE; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Chan MV; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Longhurst H; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Yaqoob MM; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Milne GL; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Zeldin DC; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.).
Warner TD; From the National Heart and Lung Institute, Imperial College London, United Kingdom (J.A.M., N.S.K., D.M.R.); Blizard Institute, Queen Mary University of London, United Kingdom (R.B.K., W.E.W., M.V.C., M.M.Y., T.D.W.); National Institute for Environmental Health Sciences, Research Triangle, NC (M.L.E., D.C.Z.); Department of Nephrology (W.E.W., M.M.Y.) and Immunology Department (H.L.), Barts Health NHS Trust, London, United Kingdom; and Departments of Pharmacology and Medicine, Vanderbilt University, Nashville, TN (G.L.M.). .; Pokaż więcej
Źródło :: Circulation research [Circ Res] 2018 Feb 16; Vol. 122 (4), pp. 555-559. Date of Electronic Publication: 2018 Jan 03.
Typ publikacji :: Case Reports; Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Kidney Transplantation*
Loss of Function Mutation*
6-Ketoprostaglandin F1 alpha/*analogs & derivatives
Allografts/*metabolism
Kidney/*metabolism
Phospholipases A2, Cytosolic/*genetics
Thromboxane B2/*analogs & derivatives
6-Ketoprostaglandin F1 alpha/metabolism ; 6-Ketoprostaglandin F1 alpha/urine ; Biomarkers/urine ; Cells, Cultured ; Female ; Humans ; Middle Aged ; Phenotype ; Phospholipases A2, Cytosolic/metabolism ; Prostaglandin-Endoperoxide Synthases/metabolism ; Thromboxane B2/metabolism ; Thromboxane B2/urine
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Acetone immersion enhanced MALDI-MS imaging of small molecule metabolites in biological tissues.
Autorzy :: Sun C; Shandong Key Laboratory of TCM Quality Control Technology, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China. Electronic address: .
Li Z; Department of Orthopedics, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, China.
Ma C; Shandong Key Laboratory of TCM Quality Control Technology, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.
Zang Q; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Li J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Liu W; Shandong Key Laboratory of TCM Quality Control Technology, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.
Zhao H; Shandong Key Laboratory of TCM Quality Control Technology, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.
Wang X; Shandong Key Laboratory of TCM Quality Control Technology, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China. Electronic address: .; Pokaż więcej
Źródło :: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2019 Nov 30; Vol. 176, pp. 112797. Date of Electronic Publication: 2019 Aug 01.
Typ publikacji :: Journal Article
MeSH Terms :: Acetone/*chemistry
Histocytological Preparation Techniques/*methods
Molecular Imaging/*methods
Osteosarcoma/*diagnostic imaging
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/*methods
Animals ; Disease Models, Animal ; Fatty Acid Synthase, Type I/analysis ; Fatty Acid Synthase, Type I/metabolism ; Glutaminase/analysis ; Glutaminase/metabolism ; Humans ; Immersion ; Mice ; Osteosarcoma/metabolism ; Osteosarcoma/pathology ; Phospholipases A2, Cytosolic/analysis ; Phospholipases A2, Cytosolic/metabolism ; Rats
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: The role of cPLA2 in Methylglyoxal-induced cell apoptosis of HUVECs.
Autorzy :: Yuan J; Jiangsu Provincial Key Lab of Cardiovascular Diseases and Molecular intervention, Department of Pharmacology, Nanjing Medical University, Nanjing 210029, PR China.
Zhu C; Jiangsu Provincial Key Lab of Cardiovascular Diseases and Molecular intervention, Department of Pharmacology, Nanjing Medical University, Nanjing 210029, PR China.
Hong Y; Jiangsu Provincial Key Lab of Cardiovascular Diseases and Molecular intervention, Department of Pharmacology, Nanjing Medical University, Nanjing 210029, PR China.
Sun Z; Jiangsu Provincial Key Lab of Cardiovascular Diseases and Molecular intervention, Department of Pharmacology, Nanjing Medical University, Nanjing 210029, PR China.
Fang X; Jiangsu Provincial Key Lab of Cardiovascular Diseases and Molecular intervention, Department of Pharmacology, Nanjing Medical University, Nanjing 210029, PR China.
Wu B; Department of Surgery, The First Affiliated Hospital, Nanchang University, PR China. Electronic address: .
Li S; Jiangsu Provincial Key Lab of Cardiovascular Diseases and Molecular intervention, Department of Pharmacology, Nanjing Medical University, Nanjing 210029, PR China. Electronic address: .; Pokaż więcej
Źródło :: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2017 May 15; Vol. 323, pp. 44-52. Date of Electronic Publication: 2017 Mar 22.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Apoptosis/*drug effects
Human Umbilical Vein Endothelial Cells/*drug effects
Phospholipases A2, Cytosolic/*metabolism
Pyruvaldehyde/*toxicity
Antioxidants/pharmacology ; Cell Survival/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Human Umbilical Vein Endothelial Cells/enzymology ; Human Umbilical Vein Endothelial Cells/pathology ; Humans ; NF-kappa B/antagonists & inhibitors ; NF-kappa B/metabolism ; Oxidative Stress/drug effects ; Phosphodiesterase Inhibitors/pharmacology ; Phospholipases A2, Cytosolic/antagonists & inhibitors ; Phospholipases A2, Cytosolic/genetics ; Phosphorylation ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA Interference ; Signal Transduction/drug effects ; Time Factors ; Transfection ; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors ; p38 Mitogen-Activated Protein Kinases/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: Regulatory Functions of Phospholipase A2.
Autorzy :: Murakami M; Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142, Japan.
Nakatani Y; Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142, Japan.
Atsumi GI; Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142, Japan.
Inoue K; Department of Health Chemistry, Faculty of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113, Japan.
Kudo I; Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142, Japan.; Pokaż więcej
Źródło :: Critical reviews in immunology [Crit Rev Immunol] 2017; Vol. 37 (2-6), pp. 127-195.
Typ publikacji :: Journal Article; Review
MeSH Terms :: Inflammation/*immunology
Phospholipases A2, Calcium-Independent/*metabolism
Phospholipases A2, Cytosolic/*metabolism
Phospholipases A2, Secretory/*metabolism
Receptors, Phospholipase A2/*metabolism
Animals ; Arachidonic Acid/immunology ; Arachidonic Acid/metabolism ; Dietary Fats/metabolism ; Eicosanoids/immunology ; Eicosanoids/metabolism ; Gene Expression Regulation, Enzymologic/immunology ; Humans ; Inflammation/pathology ; Isoenzymes/genetics ; Isoenzymes/immunology ; Isoenzymes/metabolism ; Lysophospholipids/immunology ; Lysophospholipids/metabolism ; Phospholipases A2, Calcium-Independent/genetics ; Phospholipases A2, Calcium-Independent/immunology ; Phospholipases A2, Cytosolic/genetics ; Phospholipases A2, Cytosolic/immunology ; Phospholipases A2, Secretory/genetics ; Phospholipases A2, Secretory/immunology ; Phospholipids/immunology ; Phospholipids/metabolism ; Protein Conformation ; Receptors, Phospholipase A2/immunology ; Signal Transduction/immunology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: Temozolomide has anti-tumor effects through the phosphorylation of cPLA 2 on glioblastoma cells.
Autorzy :: Tsuji S; Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Ohno Y; Department of Pharmacology, Asahi University School of Dentistry, 1851-1 Hozumi, Gifu 501-0023, Japan.
Nakamura S; Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Yamada T; Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan; Department of Neurosurgery, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Noda Y; Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Saio M; Graduate School of Health Sciences, Gunma University, 3-39-22 Showa-machi, Maebashi, Gunma 371-8514, Japan.
Iwama T; Department of Neurosurgery, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Shimazawa M; Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Hara H; Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan. Electronic address: .; Pokaż więcej
Źródło :: Brain research [Brain Res] 2019 Nov 15; Vol. 1723, pp. 146396. Date of Electronic Publication: 2019 Aug 20.
Typ publikacji :: Journal Article
MeSH Terms :: Brain Neoplasms/*drug therapy
Glioblastoma/*drug therapy
Phospholipases A2, Cytosolic/*metabolism
Temozolomide/*pharmacology
Animals ; Apoptosis/drug effects ; Brain Neoplasms/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Glioblastoma/metabolism ; Humans ; Male ; Mice ; Mice, Inbred Strains ; Phosphorylation/drug effects
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 18 18.

Tytuł :: Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis.
Autorzy :: Liu R; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Chen Y; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Fu W; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Wang S; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Cui Y; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Zhao X; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Lei ZN; Department of Pharmaceutical Science, College ofPharmacy and Health Sciences, St. John's University, New York, NY, USA.
Hettinghouse A; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Liu J; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Wang C; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Zhang C; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Bi Y; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA.
Xiao G; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Chen ZS; Department of Pharmaceutical Science, College ofPharmacy and Health Sciences, St. John's University, New York, NY, USA.
Liu CJ; Department of Orthopaedic Surgery, New York University Medical Center, New York City, New York, USA .; Departmentof Cell Biology, New York University School of Medicine, New York, NY, USA.; Pokaż więcej
Źródło :: Annals of the rheumatic diseases [Ann Rheum Dis] 2019 Nov; Vol. 78 (11), pp. 1524-1535. Date of Electronic Publication: 2019 Jul 13.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :: Arthritis, Experimental/*drug therapy
Phospholipases A2, Cytosolic/*drug effects
Terfenadine/*analogs & derivatives
Tumor Necrosis Factor Inhibitors/*pharmacology
Animals ; Mice ; Mice, Inbred DBA ; Mice, Transgenic ; Signal Transduction/drug effects ; Terfenadine/pharmacology ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: Leishmania donovani-Induced Prostaglandin E2 Generation Is Critically Dependent on Host Toll-Like Receptor 2-Cytosolic Phospholipase A2 Signaling.
Autorzy :: Bhattacharjee A; Division of Molecular Medicine, Bose Institute, Kolkata, India.
Majumder S; Division of Molecular Medicine, Bose Institute, Kolkata, India.
Das S; Division of Molecular Medicine, Bose Institute, Kolkata, India.
Ghosh S; Division of Molecular Medicine, Bose Institute, Kolkata, India.
Biswas S; Division of Molecular Medicine, Bose Institute, Kolkata, India.
Majumdar S; Division of Molecular Medicine, Bose Institute, Kolkata, India .; Pokaż więcej
Źródło :: Infection and immunity [Infect Immun] 2016 Sep 19; Vol. 84 (10), pp. 2963-73. Date of Electronic Publication: 2016 Sep 19 (Print Publication: 2016).
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Dinoprostone/*physiology
Phospholipases A2, Cytosolic/*physiology
Toll-Like Receptor 2/*physiology
Analysis of Variance ; Animals ; Blotting, Western ; Cyclooxygenase 2/metabolism ; Dinoprostone/metabolism ; Disease Models, Animal ; Enzyme-Linked Immunosorbent Assay ; Leishmania donovani ; Leishmaniasis, Visceral ; Macrophages/metabolism ; Mice ; Mice, Inbred BALB C ; Phospholipases A2, Cytosolic/metabolism ; Signal Transduction/physiology ; Toll-Like Receptor 2/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: Cytosolic phospholipase A 2 and lysophospholipid acyltransferases.
Autorzy :: Kita Y; Department of Lipidomics, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan. Electronic address: .
Shindou H; Department of Lipid Science, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Lipid Signaling, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo 162-8655, Japan; AMED-CREST, Chiyoda-ku, Tokyo 100-0004, Japan; P-CREATE, AMED, Chiyoda-ku, Tokyo 100-0004, Japan.
Shimizu T; Department of Lipidomics, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Lipid Signaling, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo 162-8655, Japan.; Pokaż więcej
Źródło :: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2019 Jun; Vol. 1864 (6), pp. 838-845. Date of Electronic Publication: 2018 Aug 09.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :: 1-Acylglycerophosphocholine O-Acyltransferase/*metabolism
Phospholipases A2, Cytosolic/*metabolism
Animals ; Cytosol/metabolism ; Humans ; Lipid Metabolism/physiology
: Czasopismo naukowe

Szczegóły

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