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Wyszukujesz frazę ""Phosphorylation"" wg kryterium: Temat


Tytuł:
A traditional gynecological medicine inhibits ovarian cancer progression and eliminates cancer stem cells via the LRPPRC-OXPHOS axis.
Autorzy:
Jiang R; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Chen Z; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Ni M; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Li X; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Ying H; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Fen J; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Wan D; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Peng C; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China.
Zhou W; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Zhejiang, 310022, Hangzhou, People's Republic of China. .
Gu L; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Jul 26; Vol. 21 (1), pp. 504. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/metabolism
Female ; Animals ; Humans ; Mitochondria/metabolism ; Disease Models, Animal ; Cell Proliferation ; Neoplastic Stem Cells/metabolism ; Cell Line, Tumor ; Neoplasm Proteins/metabolism
Czasopismo naukowe
Tytuł:
Helicase-like transcription factor (HLTF)-deleted CDX/TME model of colorectal cancer increased transcription of oxidative phosphorylation genes and diverted glycolysis to boost S-glutathionylation in lymphatic intravascular metastatic niches.
Autorzy:
Martinez-Marin D; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.; Department of Immunology and Molecular Microbiology, Texas Tech University-Health Sciences Center, Lubbock, Texas, United States of America.
Helmer RA; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.; Current address: Garrison Independent School District, Garrison, Texas, United States of America.
Kaur G; Department of Medical Education, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.
Washburn RL; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.
Martinez-Zaguilan R; Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.
Sennone SR; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.
Dufour JM; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.; Texas Center for Comparative Cancer Research, Texas Tech University School of Veterinary Medicine, Amarillo, Texas, United States of America.
Chilton BS; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.; Texas Center for Comparative Cancer Research, Texas Tech University School of Veterinary Medicine, Amarillo, Texas, United States of America.; School of Medicine Cancer Center, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Sep 08; Vol. 18 (9), pp. e0291023. Date of Electronic Publication: 2023 Sep 08 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Colorectal Neoplasms*/genetics
Humans ; Animals ; Endothelial Cells ; Tumor Microenvironment/genetics ; Transcription Factors/genetics ; Glycolysis/genetics ; Cell Line ; Disease Models, Animal ; DNA-Binding Proteins
Czasopismo naukowe
Tytuł:
Deficiency of angiopoietin-like 4 enhances CD8 T cell bioactivity via metabolic reprogramming for impairing tumour progression.
Autorzy:
Ding S; Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China.; Department of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, Jiangsu, China.
Lin Z; Department of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou, Jiangsu, China.; Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, China.
Zhang X; Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China.
Jia X; Department of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, Jiangsu, China.
Li H; Department of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, Jiangsu, China.
Fu Y; Department of Basic Medicine, School of Medicine, Soochow University, Suzhou, Jiangsu, China.
Wang X; Department of Basic Medicine, School of Medicine, Soochow University, Suzhou, Jiangsu, China.
Zhu G; Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, China.
Lu G; Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China.
Xiao W; Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China.
Gong W; Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China.; Department of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou, Jiangsu, China.; Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou, Jiangsu, China.; Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, China.
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Źródło:
Immunology [Immunology] 2023 Sep; Vol. 170 (1), pp. 28-46. Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes*
Oxidative Phosphorylation*
Animals ; Mice ; Angiopoietins ; Biological Transport ; Bone Marrow Cells
Czasopismo naukowe
Tytuł:
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6.
Autorzy:
Jia Y; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Yu X; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Liu R; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Shi L; Precision Medical Institute, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Jin H; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.; Precision Medical Institute, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Yang D; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Zhang X; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Shen Y; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Feng Y; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Zhang P; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Yang Y; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.; Precision Medical Institute, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Zhang L; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.; Precision Medical Institute, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Zhang P; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Li Z; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China. .; Key Laboratory of Environment and Genes Related to Diseases, Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China. .
He A; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China. .; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China. .
Kong G; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China. .; Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China. .; Precision Medical Institute, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China. .; Key Laboratory of Environment and Genes Related to Diseases, Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China. .
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Źródło:
Cell death & disease [Cell Death Dis] 2023 Aug 09; Vol. 14 (8), pp. 512. Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Multiple Myeloma*/genetics
Humans ; Methylation ; Protein-Arginine N-Methyltransferases/genetics ; Protein-Arginine N-Methyltransferases/metabolism ; Cell Transformation, Neoplastic ; Carcinogenesis/genetics ; Repressor Proteins/metabolism ; RNA Splicing Factors/metabolism ; Cell Cycle Proteins/metabolism ; NADH Dehydrogenase/metabolism
Czasopismo naukowe
Tytuł:
Crosstalk between oxidative phosphorylation and immune escape in cancer: a new concept of therapeutic targets selection.
Autorzy:
Qiu X; State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, China.; Department of Head and Neck Cancer Surgery, West China School of Stomatology, Sichuan University, Chengdu, China.
Li Y; State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, China.; Department of Head and Neck Cancer Surgery, West China School of Stomatology, Sichuan University, Chengdu, China.
Zhang Z; State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, China. .; Department of Head and Neck Cancer Surgery, West China School of Stomatology, Sichuan University, Chengdu, China. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2023 Aug; Vol. 46 (4), pp. 847-865. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Oxidative Phosphorylation*
Neoplasms*/genetics
Humans ; Mitochondria/metabolism ; Immunotherapy ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire.
Autorzy:
Gordon-Lipkin EM; Metabolism, Infection and Immunity Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Banerjee P; Metabolism, Infection and Immunity Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Franco JLM; Metabolism, Infection and Immunity Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Tarasenko T; Metabolism, Infection and Immunity Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Kruk S; Metabolism, Infection and Immunity Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Thompson E; Metabolism, Infection and Immunity Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Gildea DE; Bioinformatics and Scientific Programming Core, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Zhang S; Bioinformatics and Scientific Programming Core, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Wolfsberg TG; Bioinformatics and Scientific Programming Core, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Flegel WA; Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, MD, United States.
McGuire PJ; Metabolism, Infection and Immunity Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
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Corporate Authors:
NISC Comparative Sequencing Program
Źródło:
Frontiers in immunology [Front Immunol] 2023 Jul 07; Vol. 14, pp. 1142634. Date of Electronic Publication: 2023 Jul 07 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Oxidative Phosphorylation*
Leukocytes, Mononuclear*
Mice ; Animals ; Child ; Humans ; Immunity, Humoral ; B-Lymphocytes ; Antiviral Agents
Czasopismo naukowe
Tytuł:
Body mass dependence of oxidative phosphorylation efficiency in liver mitochondria from mammals.
Autorzy:
Boël M; Univ Lyon, Université Claude Bernard Lyon 1, CNRS, ENTPE, UMR 5023 LEHNA, F-69622 Villeurbanne, France; Univ Rennes, CNRS, UMR 6553 ECOBIO [(Ecosystèmes, biodiversité, évolution)], F-35000 Rennes, France. Electronic address: .
Voituron Y; Univ Lyon, Université Claude Bernard Lyon 1, CNRS, ENTPE, UMR 5023 LEHNA, F-69622 Villeurbanne, France. Electronic address: https://twitter.com/YVoituron.
Roussel D; Univ Lyon, Université Claude Bernard Lyon 1, CNRS, ENTPE, UMR 5023 LEHNA, F-69622 Villeurbanne, France. Electronic address: .
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Źródło:
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology [Comp Biochem Physiol A Mol Integr Physiol] 2023 Oct; Vol. 284, pp. 111490. Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Mitochondria, Liver*/metabolism
Animals ; Adenosine Triphosphate/metabolism ; Mitochondria/metabolism ; Mammals/metabolism ; Oxygen Consumption/physiology
Czasopismo naukowe
Tytuł:
Metabolic shift towards oxidative phosphorylation reduces cell-density-induced cancer-stem-cell-like characteristics in prostate cancer in vitro.
Autorzy:
Lai HW; Center for Photodynamic Medicine, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Kasai M; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, 226-8501 Kanagawa, Japan.
Yamamoto S; Department of Urology, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Fukuhara H; Center for Photodynamic Medicine, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.; Department of Urology, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Karashima T; Department of Pathology, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Kurabayashi A; Department of Pathology, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Furihata M; Department of Pathology, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Hanazaki K; Center for Photodynamic Medicine, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.; Department of Urology, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Inoue K; Center for Photodynamic Medicine, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.; Department of Urology, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.
Ogura SI; Center for Photodynamic Medicine, Kochi Medical School, Kochi University, Nankoku, 783-8505 Kochi, Japan.; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, 226-8501 Kanagawa, Japan.
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Źródło:
Biology open [Biol Open] 2023 Apr 15; Vol. 12 (4). Date of Electronic Publication: 2023 Apr 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Prostatic Neoplasms*/genetics
Male ; Humans ; Neoplasm Recurrence, Local/metabolism ; Neoplasm Recurrence, Local/pathology ; Glycolysis ; Neoplastic Stem Cells/pathology
Czasopismo naukowe
Tytuł:
Regulative Roles of Metabolic Plasticity Caused by Mitochondrial Oxidative Phosphorylation and Glycolysis on the Initiation and Progression of Tumorigenesis.
Autorzy:
Niu N; Shenzhen Engineering Labortaory for Marine Algal Biotechnology, Longhua Innovation Institute for Biotechnology, College of Life Sciences and Oceanography, Lihu Campus of Shenzhen University, Shenzhen 518055, China.; College of Physics and Optoelectronic Engineering, Canghai Campus of Shenzhen University, Shenzhen 518060, China.
Ye J; Shenzhen Engineering Labortaory for Marine Algal Biotechnology, Longhua Innovation Institute for Biotechnology, College of Life Sciences and Oceanography, Lihu Campus of Shenzhen University, Shenzhen 518055, China.
Hu Z; Shenzhen Engineering Labortaory for Marine Algal Biotechnology, Longhua Innovation Institute for Biotechnology, College of Life Sciences and Oceanography, Lihu Campus of Shenzhen University, Shenzhen 518055, China.
Zhang J; Shenzhen Engineering Labortaory for Marine Algal Biotechnology, Longhua Innovation Institute for Biotechnology, College of Life Sciences and Oceanography, Lihu Campus of Shenzhen University, Shenzhen 518055, China.
Wang Y; Shenzhen Engineering Labortaory for Marine Algal Biotechnology, Longhua Innovation Institute for Biotechnology, College of Life Sciences and Oceanography, Lihu Campus of Shenzhen University, Shenzhen 518055, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 11; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Oxidative Phosphorylation*
Carcinoma*/metabolism
Humans ; Glycolysis ; Mitochondria/metabolism ; Cell Transformation, Neoplastic/metabolism
Czasopismo naukowe
Tytuł:
Transcriptome analysis reveals that knocking out BmNPV iap2 induces apoptosis by inhibiting the oxidative phosphorylation pathway.
Autorzy:
Li K; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Dong Z; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China; Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing 400716, China. Electronic address: .
Dong F; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Hu Z; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Huang L; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Wang J; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Chen P; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China; Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing 400716, China.
Lu C; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China; Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing 400716, China.
Pan M; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China; Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing 400716, China. Electronic address: cs_.
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Apr 01; Vol. 233, pp. 123482. Date of Electronic Publication: 2023 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Phosphorylation*
Bombyx*/metabolism
Animals ; Gene Expression Profiling ; Transcriptome ; Apoptosis/genetics
SCR Organism:
Bombyx mori nucleopolyhedrovirus
Czasopismo naukowe
Tytuł:
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine.
Autorzy:
Cao J; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.
Li M; State Key Laboratory of Membrane Biology, School of Medicine, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, China.
Liu K; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.
Shi X; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Sui N; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; Qufu Normal University, Qufu 273165, China.
Yao Y; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; Qufu Normal University, Qufu 273165, China.
Wang X; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Li S; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Tian Y; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Tan S; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Zhao Q; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.
Wang L; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Chai X; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.
Zhang L; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Liu C; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Li X; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Chang Z; State Key Laboratory of Membrane Biology, School of Medicine, Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, China.
Li D; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Zhao T; State Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło:
Protein & cell [Protein Cell] 2023 May 08; Vol. 14 (5), pp. 376-381.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Acetylglucosamine*
Uridine Diphosphate N-Acetylglucosamine/metabolism
Raport
Tytuł:
High-content high-throughput imaging reveals distinct connections between mitochondrial morphology and functionality for OXPHOS complex I, III, and V inhibitors.
Autorzy:
van der Stel W; Division of Drug Discovery and Safety, Leiden Academic Centre of Drug Research, Leiden University, Einsteinweg, 55, 2333 CC, Leiden, The Netherlands.
Yang H; Division of Drug Discovery and Safety, Leiden Academic Centre of Drug Research, Leiden University, Einsteinweg, 55, 2333 CC, Leiden, The Netherlands.
le Dévédec SE; Division of Drug Discovery and Safety, Leiden Academic Centre of Drug Research, Leiden University, Einsteinweg, 55, 2333 CC, Leiden, The Netherlands.
van de Water B; Division of Drug Discovery and Safety, Leiden Academic Centre of Drug Research, Leiden University, Einsteinweg, 55, 2333 CC, Leiden, The Netherlands.
Beltman JB; Division of Drug Discovery and Safety, Leiden Academic Centre of Drug Research, Leiden University, Einsteinweg, 55, 2333 CC, Leiden, The Netherlands.
Danen EHJ; Division of Drug Discovery and Safety, Leiden Academic Centre of Drug Research, Leiden University, Einsteinweg, 55, 2333 CC, Leiden, The Netherlands. .
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Źródło:
Cell biology and toxicology [Cell Biol Toxicol] 2023 Apr; Vol. 39 (2), pp. 415-433. Date of Electronic Publication: 2022 May 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Mitochondria*/metabolism
Mitochondrial Proteins/metabolism ; Adenosine Triphosphate/pharmacology
Czasopismo naukowe
Tytuł:
Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis.
Autorzy:
Wculek SK; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain. Electronic address: .
Heras-Murillo I; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain.
Mastrangelo A; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain.
Mañanes D; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain.
Galán M; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain.
Miguel V; Program of Physiological and Pathological Processes, Centro de Biología Molecular 'Severo Ochoa' (CBMSO, CSIC-UAM), 28049 Madrid, Spain.
Curtabbi A; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain; Centro de Investigaciónes Biomédicas en Red en Fragilidad y Envejecimiento Saludabe (CIBERFES), 28029 Madrid, Spain.
Barbas C; Centro de Metabolómica y Bioanálisis (CEMBIO), School of Pharmacy, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, 28660 Madrid, Spain.
Chandel NS; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Enríquez JA; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain; Centro de Investigaciónes Biomédicas en Red en Fragilidad y Envejecimiento Saludabe (CIBERFES), 28029 Madrid, Spain.
Lamas S; Program of Physiological and Pathological Processes, Centro de Biología Molecular 'Severo Ochoa' (CBMSO, CSIC-UAM), 28049 Madrid, Spain.
Sancho D; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain. Electronic address: .
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Źródło:
Immunity [Immunity] 2023 Mar 14; Vol. 56 (3), pp. 516-530.e9. Date of Electronic Publication: 2023 Feb 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Inflammation*/metabolism
Humans ; Mice ; Animals ; Macrophages/metabolism ; Homeostasis ; Lipids ; Adipose Tissue/metabolism
Czasopismo naukowe
Tytuł:
Goldilocks calcium concentrations and the regulation of oxidative phosphorylation: Too much, too little, or just right.
Autorzy:
Vilas-Boas EA; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, São Paulo, Brazil. Electronic address: .
Cabral-Costa JV; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Ramos VM; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Caldeira da Silva CC; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Kowaltowski AJ; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, São Paulo, Brazil. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Mar; Vol. 299 (3), pp. 102904. Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium*/metabolism
Mitochondria*/metabolism
Oxidative Phosphorylation*
Animals ; Mice
Czasopismo naukowe
Tytuł:
Juglone promotes antitumor activity against prostate cancer via suppressing glycolysis and oxidative phosphorylation.
Autorzy:
Hu C; College of Laboratory Medicine, Jilin Medical University, Jilin City, Jilin, People's Republic of China.
Xu H; Clinical Laboratory Department, Changchun Obstetrics and Gynecology Hospital, Changchun city, Jilin, People's Republic of China.
Li Z; College of Laboratory Medicine, Jilin Medical University, Jilin City, Jilin, People's Republic of China.
Liu D; College of Laboratory Medicine, Jilin Medical University, Jilin City, Jilin, People's Republic of China.
Zhang S; College of medical technology, Beihua university, Jilin City, Jilin, People's Republic of China.
Fang F; College of Laboratory Medicine, Jilin Medical University, Jilin City, Jilin, People's Republic of China.
Wang L; Department of Urology Surgery, Affiliated Hospital of Jilin Medical University, Jilin City, Jilin, People's Republic of China.
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Źródło:
Phytotherapy research : PTR [Phytother Res] 2023 Feb; Vol. 37 (2), pp. 515-526. Date of Electronic Publication: 2022 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Phosphorylation*
Prostatic Neoplasms*/drug therapy
Humans ; Male ; Glycolysis/physiology ; Energy Metabolism ; Hexokinase/metabolism ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Cannabinoid 1 (CB 1 ) receptor arrestin subtype-selectivity and phosphorylation dependence.
Autorzy:
Manning JJ; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Rawcliffe G; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Finlay DB; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Glass M; Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2023 Feb; Vol. 180 (3), pp. 369-382. Date of Electronic Publication: 2022 Nov 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arrestins*/metabolism
Phosphorylation*
Receptor, Cannabinoid, CB1*/metabolism
beta-Arrestin 1/metabolism ; beta-Arrestin 2/metabolism ; beta-Arrestins/metabolism ; Cannabinoids/metabolism ; GTP-Binding Proteins/metabolism ; Humans
Czasopismo naukowe
Tytuł:
Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin.
Autorzy:
Ramirez MP; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
Rajaganapathy S; Department of Electrical and Computer Engineering, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
Hagerty AR; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
Hua C; Department of Electrical and Computer Engineering, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
Baxter GC; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
Vavra J; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
Gordon WR; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
Muretta JM; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
Salapaka MV; Department of Electrical and Computer Engineering, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
Ervasti JM; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota - Twin Cities, Minneapolis, MN, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Feb; Vol. 299 (2), pp. 102847. Date of Electronic Publication: 2022 Dec 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Phosphorylation*
Utrophin*/chemistry
Utrophin*/genetics
Animals ; Dystrophin/genetics ; Mice, Inbred mdx ; Muscle, Skeletal/metabolism ; Muscular Dystrophy, Duchenne/genetics ; Bacteria ; Insecta
Czasopismo naukowe
Tytuł:
The Warburg effect and mitochondrial oxidative phosphorylation: Friends or foes?
Autorzy:
Martins Pinto M; CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France; CBMN, Allée de Geoffroy St Hilaire Bât, B1433600 Pessac, France; Université de Bordeaux, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France.
Paumard P; CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France; Université de Bordeaux, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France.
Bouchez C; CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France; Université de Bordeaux, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France.
Ransac S; CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France; Université de Bordeaux, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France.
Duvezin-Caubet S; CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France; Université de Bordeaux, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France.
Mazat JP; CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France; Université de Bordeaux, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France.
Rigoulet M; CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France; Université de Bordeaux, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France.
Devin A; CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France; Université de Bordeaux, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Bioenergetics [Biochim Biophys Acta Bioenerg] 2023 Jan 01; Vol. 1864 (1), pp. 148931. Date of Electronic Publication: 2022 Oct 29.
Typ publikacji:
Review; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Glycolysis*
Humans ; Mitochondria/metabolism ; Cell Respiration ; Adenosine Triphosphate/metabolism
Czasopismo naukowe
Tytuł:
Phosphorylation states greatly regulate the activity and gating properties of Ca v 3.1 T-type Ca channels.
Autorzy:
Jeong S; Department of Life Science, Sogang University, Seoul, South Korea.
Shim JS; Department of Physiology, Kyung-Hee University, Seoul, South Korea.
Sin SK; Department of Physiology, Kyung-Hee University, Seoul, South Korea.
Park KS; Department of Physiology, Kyung-Hee University, Seoul, South Korea.
Lee JH; Department of Life Science, Sogang University, Seoul, South Korea.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2023 Jan; Vol. 238 (1), pp. 210-226. Date of Electronic Publication: 2022 Dec 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Phosphorylation*
Calcium Channels, T-Type*/metabolism
Animals ; Humans ; Mice ; Rats ; HEK293 Cells ; Kinetics ; Mutation ; Xenopus ; Mutagenesis, Site-Directed
Czasopismo naukowe
Tytuł:
Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation.
Autorzy:
Todorova V; Laboratory for Retinal Cell Biology, Department of Ophthalmology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, Switzerland.
Stauffacher MF; Laboratory for Retinal Cell Biology, Department of Ophthalmology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, Switzerland.
Ravotto L; Institute of Pharmacology and Toxicology and Neuroscience Center Zurich, University and ETH Zurich, Winterthurerstr. 190, 8057, Zurich, Switzerland.
Nötzli S; Laboratory for Retinal Cell Biology, Department of Ophthalmology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, Switzerland.
Karademir D; Laboratory for Retinal Cell Biology, Department of Ophthalmology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, Switzerland.
Ebner LJA; Laboratory for Retinal Cell Biology, Department of Ophthalmology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, Switzerland.
Imsand C; Laboratory for Retinal Cell Biology, Department of Ophthalmology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, Switzerland.
Merolla L; Laboratory for Retinal Cell Biology, Department of Ophthalmology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, Switzerland.
Hauck SM; Metabolomics and Proteomics Core, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstraße 1, 85764, Munich, Germany.
Samardzija M; Laboratory for Retinal Cell Biology, Department of Ophthalmology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, Switzerland.
Saab AS; Institute of Pharmacology and Toxicology and Neuroscience Center Zurich, University and ETH Zurich, Winterthurerstr. 190, 8057, Zurich, Switzerland.
Barros LF; Centro de Estudios Científicos (CECs), Valdivia, Chile.; Universidad San Sebastián, Valdivia, Chile.
Weber B; Institute of Pharmacology and Toxicology and Neuroscience Center Zurich, University and ETH Zurich, Winterthurerstr. 190, 8057, Zurich, Switzerland.
Grimm C; Laboratory for Retinal Cell Biology, Department of Ophthalmology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, Switzerland. .
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2023 Mar 07; Vol. 18 (1), pp. 15. Date of Electronic Publication: 2023 Mar 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Phosphorylation*
Retinal Degeneration*
Humans ; Glucose ; Hypoxia ; Lactic Acid ; Retinal Rod Photoreceptor Cells
Czasopismo naukowe

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