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Wyszukujesz frazę ""Photosensitizing Agents"" wg kryterium: Temat


Tytuł:
Ultrasound-activated prodrug-loaded liposome for efficient cancer targeting therapy without chemotherapy-induced side effects.
Autorzy:
Jiang Y; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.
Chen H; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.; Research Center for Life Science and Human Health, Binjiang Institute of Zhejiang University, Hangzhou, 310053, China.
Lin T; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.
Zhang C; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.
Shen J; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.
Chen J; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.
Zhao Y; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.
Xu W; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China.
Wang G; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China. .; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China. .
Huang P; Department of Ultrasound in Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China. .; Research Center of Ultrasound in Medicine and Biomedical Engineering, The Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, China. .; Research Center for Life Science and Human Health, Binjiang Institute of Zhejiang University, Hangzhou, 310053, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Jan 03; Vol. 22 (1), pp. 2. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Prodrugs*/pharmacology
Prodrugs*/therapeutic use
Adenocarcinoma*/drug therapy
Colonic Neoplasms*/diagnostic imaging
Colonic Neoplasms*/drug therapy
Antineoplastic Agents*/therapeutic use
Nanoparticles*/metabolism
Photochemotherapy*
Humans ; Animals ; Mice ; Liposomes ; Reactive Oxygen Species/metabolism ; Cell Line, Tumor ; Photosensitizing Agents/therapeutic use ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Ruthenium(II)-Arene Curcuminoid Complexes as Photosensitizer Agents for Antineoplastic and Antimicrobial Photodynamic Therapy: In Vitro and In Vivo Insights.
Autorzy:
Marras E; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Balacchi CJ; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Orlandi V; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Caruso E; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Brivio MF; Department of Theoretical and Applied Sciences (DiSTA), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Bolognese F; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Mastore M; Department of Theoretical and Applied Sciences (DiSTA), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Malacarne MC; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Rossi M; Department of Chemistry, Vassar College, Poughkeepsie, NY 12604, USA.
Caruso F; Department of Chemistry, Vassar College, Poughkeepsie, NY 12604, USA.
Vivona V; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Ferrario N; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Gariboldi MB; Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 11; Vol. 28 (22). Date of Electronic Publication: 2023 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/pharmacology
Ruthenium*/chemistry
Curcumin*/pharmacology
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Antineoplastic Agents*/chemistry
Photochemotherapy*
Humans ; Photosensitizing Agents/chemistry ; Diarylheptanoids ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use
Czasopismo naukowe
Tytuł:
Multifunctional Novel Nanoplatform for Effective Synergistic Chemo-Photodynamic Therapy of Breast Cancer by Enhancing DNA Damage and Disruptions of Its Reparation.
Autorzy:
Huang Z; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing Collaborative Innovation Center of Targeted and Innovative Therapeutics, College of Pharmacy, Chongqing University of Arts and Sciences, Chongqing 402160, China.; Key Laboratory of Bio-Theological Science and Technology of Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400045, China.
Xian T; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing Collaborative Innovation Center of Targeted and Innovative Therapeutics, College of Pharmacy, Chongqing University of Arts and Sciences, Chongqing 402160, China.
Meng X; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing Collaborative Innovation Center of Targeted and Innovative Therapeutics, College of Pharmacy, Chongqing University of Arts and Sciences, Chongqing 402160, China.
Hu H; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing Collaborative Innovation Center of Targeted and Innovative Therapeutics, College of Pharmacy, Chongqing University of Arts and Sciences, Chongqing 402160, China.
Gao L; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing Collaborative Innovation Center of Targeted and Innovative Therapeutics, College of Pharmacy, Chongqing University of Arts and Sciences, Chongqing 402160, China.
Huang J; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing Collaborative Innovation Center of Targeted and Innovative Therapeutics, College of Pharmacy, Chongqing University of Arts and Sciences, Chongqing 402160, China.
Yang D; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing Collaborative Innovation Center of Targeted and Innovative Therapeutics, College of Pharmacy, Chongqing University of Arts and Sciences, Chongqing 402160, China.
Ou K; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing Collaborative Innovation Center of Targeted and Innovative Therapeutics, College of Pharmacy, Chongqing University of Arts and Sciences, Chongqing 402160, China.
Wang B; Key Laboratory of Bio-Theological Science and Technology of Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400045, China.
Zhang Y; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing Collaborative Innovation Center of Targeted and Innovative Therapeutics, College of Pharmacy, Chongqing University of Arts and Sciences, Chongqing 402160, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Oct 07; Vol. 28 (19). Date of Electronic Publication: 2023 Oct 07.
Typ publikacji:
Journal Article
MeSH Terms:
Photochemotherapy*
Antineoplastic Agents*
Nanoparticles*
Triple Negative Breast Neoplasms*
Humans ; Photosensitizing Agents/pharmacology ; Reactive Oxygen Species/metabolism ; Poly(ADP-ribose) Polymerases/metabolism ; DNA Damage ; Cell Line, Tumor ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Iodinated cyanine dye-based nanosystem for synergistic phototherapy and hypoxia-activated bioreductive therapy.
Autorzy:
Dong Y; Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
Zhou L; The Key Laboratory of Traditional Chinese Medicine Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine, School of Pharmacy, Binzhou Medical University, Yantai, China.
Shen Z; Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
Ma Q; Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
Zhao Y; Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
Sun Y; Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
Cao J; Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, China.
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Źródło:
Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 238-253.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Hypoxia/*pathology
Nanoparticle Drug Delivery System/*chemistry
Photosensitizing Agents/*pharmacology
Phototherapy/*methods
Tirapazamine/*pharmacology
Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacokinetics ; Cell Survival/drug effects ; Chemistry, Pharmaceutical ; Chromosome Aberrations/drug effects ; DNA Damage/drug effects ; Drug Carriers/chemistry ; Drug Liberation ; Liposomes/chemistry ; Mice ; Mice, Inbred BALB C ; Particle Size ; Photosensitizing Agents/administration & dosage ; Photosensitizing Agents/pharmacokinetics ; Reactive Oxygen Species/metabolism ; Surface Properties ; Tirapazamine/administration & dosage ; Tirapazamine/pharmacokinetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Cytotoxic Effects of Combinative ZnPcS 4 Photosensitizer Photodynamic Therapy (PDT) and Cannabidiol (CBD) on a Cervical Cancer Cell Line.
Autorzy:
Razlog R; Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein, P.O. Box 17011, Johannesburg 2028, South Africa.
Kruger CA; Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein, P.O. Box 17011, Johannesburg 2028, South Africa.
Abrahamse H; Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein, P.O. Box 17011, Johannesburg 2028, South Africa.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 24; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 24.
Typ publikacji:
Journal Article
MeSH Terms:
Photochemotherapy*/methods
Cannabidiol*/pharmacology
Cannabidiol*/therapeutic use
Uterine Cervical Neoplasms*/pathology
Antineoplastic Agents*/therapeutic use
Female ; Humans ; Photosensitizing Agents/pharmacology ; Photosensitizing Agents/therapeutic use ; HeLa Cells ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Nanoscale Two-Dimensional Fe -Based Metal-Organic Frameworks of Porphyrin Ligand for the Photodynamic Therapy of Breast Cancer.
Autorzy:
Li Q; College of Chemistry, Chemical Engineering, and Materials Science, Soochow University, Suzhou 215123, China.
Xu BW; College of Chemistry, Chemical Engineering, and Materials Science, Soochow University, Suzhou 215123, China.
Zou YM; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Niu RJ; College of Chemistry, Chemical Engineering, and Materials Science, Soochow University, Suzhou 215123, China.
Chen JX; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Zhang WH; College of Chemistry, Chemical Engineering, and Materials Science, Soochow University, Suzhou 215123, China.
Young DJ; Faculty of Science and Technology, Charles Darwin University, Darwin, NT 0909, Australia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 24; Vol. 28 (5). Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Metal-Organic Frameworks*/pharmacology
Breast Neoplasms*/drug therapy
Porphyrins*/pharmacology
Photochemotherapy*/methods
Neoplasms*/drug therapy
Antineoplastic Agents*/pharmacology
Humans ; Female ; Hydrogen Peroxide/pharmacology ; Ligands ; Ferrous Compounds/pharmacology ; Photosensitizing Agents/pharmacology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Highly Charged Ru(II) Polypyridyl Complexes as Photosensitizer Agents in Photodynamic Therapy of Epithelial Ovarian Cancer Cells.
Autorzy:
Conti L; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Giacomazzo GE; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Valtancoli B; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Perfetti M; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Privitera A; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Giorgi C; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Sfragano PS; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Palchetti I; Department of Chemistry 'Ugo Schiff', University of Florence, 50019 Sesto Fiorentino, Italy.
Pecchioli S; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
Bruni P; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
Cencetti F; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 01; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:
Journal Article
MeSH Terms:
Photochemotherapy*
Ruthenium*/pharmacology
Ruthenium*/chemistry
Ovarian Neoplasms*/drug therapy
Coordination Complexes*/pharmacology
Coordination Complexes*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Humans ; Female ; Photosensitizing Agents/pharmacology ; Photosensitizing Agents/chemistry ; Carcinoma, Ovarian Epithelial/drug therapy ; Cell Line, Tumor ; Reactive Oxygen Species ; HeLa Cells ; Neoplasm Recurrence, Local
Czasopismo naukowe
Tytuł:
NIR-II emissive AIEgen photosensitizers enable ultrasensitive imaging-guided surgery and phototherapy to fully inhibit orthotopic hepatic tumors.
Autorzy:
Jia R; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Xu H; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Wang C; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Su L; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Jing J; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Xu S; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Zhou Y; State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China.
Sun W; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
Song J; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Chen X; Departments of Diagnostic Radiology and Surgery, Clinical Imaging Research Centre, Centre for Translational Medicine, Nanomedicine Translational Research Program, NUS Center for Nanomedicine, Yong Loo Lin School of Medicine, Singapore, Singapore.; Departments of Chemical and Biomolecular Engineering, and Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, Singapore.
Chen H; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2021 Dec 13; Vol. 19 (1), pp. 419. Date of Electronic Publication: 2021 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Liver Neoplasms*/diagnostic imaging
Liver Neoplasms*/therapy
Photosensitizing Agents*/chemistry
Photosensitizing Agents*/pharmacology
Spectroscopy, Near-Infrared/*methods
Surgery, Computer-Assisted/*methods
Animals ; Liver/drug effects ; Mice ; Mice, Inbred BALB C ; Neoplasms, Experimental/metabolism ; Neoplasms, Experimental/pathology ; Photochemotherapy
Czasopismo naukowe
Tytuł:
Light-Enhanced Cytotoxicity of Doxorubicin by Photoactivation.
Autorzy:
Greco G; Dipartimento di Chimica 'Giacomo Ciamician', Alma Mater Studiorum-Università di Bologna,40126 Bologna, Italy.
Ulfo L; Dipartimento di Farmacia e Biotecnologie, Alma Mater Studiorum-Università di Bologna, 40126 Bologna, Italy.
Turrini E; Dipartimento di Scienze per la Qualità della Vita, Alma Mater Studiorum-Università di Bologna, 47921 Rimini, Italy.
Marconi A; Dipartimento di Chimica 'Giacomo Ciamician', Alma Mater Studiorum-Università di Bologna,40126 Bologna, Italy.
Costantini PE; Dipartimento di Farmacia e Biotecnologie, Alma Mater Studiorum-Università di Bologna, 40126 Bologna, Italy.
Marforio TD; Dipartimento di Chimica 'Giacomo Ciamician', Alma Mater Studiorum-Università di Bologna,40126 Bologna, Italy.
Mattioli EJ; Dipartimento di Chimica 'Giacomo Ciamician', Alma Mater Studiorum-Università di Bologna,40126 Bologna, Italy.
Di Giosia M; Dipartimento di Chimica 'Giacomo Ciamician', Alma Mater Studiorum-Università di Bologna,40126 Bologna, Italy.
Danielli A; Dipartimento di Farmacia e Biotecnologie, Alma Mater Studiorum-Università di Bologna, 40126 Bologna, Italy.
Fimognari C; Dipartimento di Scienze per la Qualità della Vita, Alma Mater Studiorum-Università di Bologna, 47921 Rimini, Italy.
Calvaresi M; Dipartimento di Chimica 'Giacomo Ciamician', Alma Mater Studiorum-Università di Bologna,40126 Bologna, Italy.
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Źródło:
Cells [Cells] 2023 Jan 21; Vol. 12 (3). Date of Electronic Publication: 2023 Jan 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Photochemotherapy*
Antineoplastic Agents*/pharmacology
Reactive Oxygen Species/metabolism ; Doxorubicin/pharmacology ; Photosensitizing Agents/pharmacology
Czasopismo naukowe
Tytuł:
Chlorin e6-Biotin Conjugates for Tumor-Targeting Photodynamic Therapy.
Autorzy:
Liu W; Lab of Molecular Imaging, Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.
Ma X; Department of Oncology, Nanjing Baiyi Hospital, Jinling Clinical College of Nanjing Medical University, Nanjing 210000, China.
Jin Y; Lab of Molecular Imaging, Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.
Zhang J; Lab of Molecular Imaging, Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.
Li Y; Lab of Molecular Imaging, Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.
Tang Y; Lab of Molecular Imaging, Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.
Song Y; Department of Respiratory and Critical Care Medicine, Jinling Clinical College of Nanjing Medical University, Nanjing 210000, China.
Wang S; Lab of Molecular Imaging, Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Dec 03; Vol. 26 (23). Date of Electronic Publication: 2021 Dec 03.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Biotin/*pharmacology
Chlorophyllides/*pharmacology
Photosensitizing Agents/*pharmacology
Antineoplastic Agents/chemistry ; Biotin/analogs & derivatives ; Cell Survival/drug effects ; Chlorophyllides/chemistry ; HeLa Cells ; Humans ; Neoplasms/drug therapy ; Photochemotherapy ; Photosensitizing Agents/chemistry
Czasopismo naukowe
Tytuł:
Computational Analysis of Photophysical Properties and Reactivity of a New Phototherapeutic Cyclometalated Au(III)-Hydride Complex.
Autorzy:
Scoditti S; Department of Chemistry and Chemical Technologies, University of Calabria, Via P. Bucci, 87036, Rende, CS, Italy.
Mazzone G; Department of Chemistry and Chemical Technologies, University of Calabria, Via P. Bucci, 87036, Rende, CS, Italy.
Sicilia E; Department of Chemistry and Chemical Technologies, University of Calabria, Via P. Bucci, 87036, Rende, CS, Italy.
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Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Nov 05; Vol. 27 (62), pp. 15528-15535. Date of Electronic Publication: 2021 Oct 06.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*
Photosensitizing Agents*
Gold ; Ligands ; Light
Czasopismo naukowe
Tytuł:
Rationally designed upconversion nanoparticles for NIR light-controlled lysosomal escape and nucleus-based photodynamic therapy.
Autorzy:
Chen X; Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, 117583, Singapore.
Zhang Y; Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, 117583, Singapore.
Zhang X; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore.
Zhang Z; Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, 117583, Singapore.
Zhang Y; Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, 117583, Singapore. .; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, 117456, Singapore. .
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Źródło:
Mikrochimica acta [Mikrochim Acta] 2021 Sep 22; Vol. 188 (10), pp. 349. Date of Electronic Publication: 2021 Sep 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*administration & dosage
Metals, Rare Earth/*administration & dosage
Nanoparticles/*administration & dosage
Photosensitizing Agents/*administration & dosage
Rose Bengal/*administration & dosage
Silicon Dioxide/*administration & dosage
Antineoplastic Agents/chemistry ; Antineoplastic Agents/radiation effects ; Cell Nucleus/chemistry ; Cell Nucleus/radiation effects ; Cell Survival/drug effects ; Humans ; Light ; Lysosomes/chemistry ; MCF-7 Cells ; Metals, Rare Earth/chemistry ; Metals, Rare Earth/radiation effects ; Nanoparticles/chemistry ; Nanoparticles/radiation effects ; Photochemotherapy ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/radiation effects ; Reactive Oxygen Species/chemistry ; Rose Bengal/chemistry ; Rose Bengal/radiation effects ; Silicon Dioxide/chemistry ; Silicon Dioxide/radiation effects ; Spheroids, Cellular/drug effects ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
Unraveling the Photodynamic Activity of Cationic Benzoporphyrin-Based Photosensitizers against Bladder Cancer Cells.
Autorzy:
Gomes ATPC; LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Center for Interdisciplinary Research in Health (CIIS), Faculty of Dental Medicine, Universidade Católica Portuguesa, 3504-505 Viseu, Portugal.
Neves MGPMS; LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Fernandes R; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Ribeiro CF; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Cavaleiro JAS; LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Moura NMM; LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Sep 01; Vol. 26 (17). Date of Electronic Publication: 2021 Sep 01.
Typ publikacji:
Journal Article
MeSH Terms:
Photochemotherapy*
Antineoplastic Agents/*pharmacology
Photosensitizing Agents/*pharmacology
Porphyrins/*pharmacology
Urinary Bladder Neoplasms/*drug therapy
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cations/chemical synthesis ; Cations/chemistry ; Cations/pharmacology ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Photosensitizing Agents/chemical synthesis ; Photosensitizing Agents/chemistry ; Porphyrins/chemical synthesis ; Porphyrins/chemistry ; Structure-Activity Relationship ; Urinary Bladder Neoplasms/pathology
Czasopismo naukowe
Tytuł:
Metal Nanoparticles for Photodynamic Therapy: A Potential Treatment for Breast Cancer.
Autorzy:
Shang L; Department of Breast Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Zhou X; Department of PET/CT Center, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Zhang J; Department of Breast Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Shi Y; Department of Breast Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Zhong L; Department of Breast Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.; Department of Breast Surgery, Sixth Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Oct 29; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Photochemotherapy*
Antineoplastic Agents/*pharmacology
Breast Neoplasms/*drug therapy
Metal Nanoparticles/*chemistry
Photosensitizing Agents/*pharmacology
Antineoplastic Agents/chemistry ; Breast Neoplasms/metabolism ; Female ; Humans ; Photosensitizing Agents/chemistry ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B.
Autorzy:
Ding Y; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Liu W; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Wu J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Zheng X; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Ge J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Ren H; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Zhang W; Center Of Super-Diamond and Advanced Films (COSDAF) & Department of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, P. R. China.
Lee CS; Center Of Super-Diamond and Advanced Films (COSDAF) & Department of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, P. R. China.
Wang P; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
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Źródło:
Chemistry, an Asian journal [Chem Asian J] 2021 May 17; Vol. 16 (10), pp. 1221-1224. Date of Electronic Publication: 2021 Apr 21.
Typ publikacji:
Journal Article
MeSH Terms:
Photochemotherapy*
Ultrasonic Waves*
Antineoplastic Agents/*pharmacology
Metal-Organic Frameworks/*pharmacology
Perylene/*analogs & derivatives
Photosensitizing Agents/*pharmacology
Quinones/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Metal-Organic Frameworks/chemical synthesis ; Metal-Organic Frameworks/chemistry ; Models, Molecular ; Particle Size ; Perylene/chemistry ; Perylene/pharmacology ; Photosensitizing Agents/chemical synthesis ; Photosensitizing Agents/chemistry ; Quinones/chemistry
Czasopismo naukowe
Tytuł:
Novel Short PEG Chain-Substituted Porphyrins: Synthesis, Photochemistry, and In Vitro Photodynamic Activity against Cancer Cells.
Autorzy:
Lazewski D; Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.
Kucinska M; Department of Toxicology, Poznan University of Medical Sciences, Dojazd 30 Street, 60-631 Poznan, Poland.
Potapskiy E; Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.
Kuzminska J; Department of Pharmaceutical Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.
Tezyk A; Department of Forensic Medicine, Poznan University of Medical Sciences, Swiecickiego 6 Street, 60-781 Poznan, Poland.
Popenda L; NanoBioMedical Centre, Adam Mickiewicz University in Poznan, Wszechnicy Piastowskiej 3 Street, 61-614 Poznan, Poland.
Jurga S; NanoBioMedical Centre, Adam Mickiewicz University in Poznan, Wszechnicy Piastowskiej 3 Street, 61-614 Poznan, Poland.
Teubert A; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14 Street, 61-704 Poznan, Poland.
Gdaniec Z; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14 Street, 61-704 Poznan, Poland.
Kujawski J; Department of Organic Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.
Grzyb K; Faculty of Chemistry, Adam Mickiewicz University in Poznan, Uniwersytetu Poznanskiego 8 Street, 61-614 Poznan, Poland.
Pedzinski T; Faculty of Chemistry, Adam Mickiewicz University in Poznan, Uniwersytetu Poznanskiego 8 Street, 61-614 Poznan, Poland.; Center for Advanced Technology, Adam Mickiewicz University in Poznan, Uniwersytetu Poznanskiego 10 Street, 61-614 Poznan, Poland.
Murias M; Department of Toxicology, Poznan University of Medical Sciences, Dojazd 30 Street, 60-631 Poznan, Poland.; Center for Advanced Technology, Adam Mickiewicz University in Poznan, Uniwersytetu Poznanskiego 10 Street, 61-614 Poznan, Poland.
Wierzchowski M; Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 02; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 02.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*
Neoplasms*
Photochemotherapy*/methods
Porphyrins*/chemistry
Humans ; Photochemistry ; Photosensitizing Agents/chemistry ; Zinc/pharmacology
Czasopismo naukowe
Tytuł:
Self-assembly supramolecular drug delivery system for combination of photodynamic therapy and chemotherapy.
Autorzy:
Zhang L; Department of Pharmacy, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Jin T; Department of Pharmacy, The Second People's Hospital of Lianyungang, Lianyungang, China.
Sun J; Department of Pharmacy, The Second Hospital of Shandong University, Jinan, China.
Chen X; Department of Pharmacy, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
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Źródło:
Journal of microencapsulation [J Microencapsul] 2021 Mar; Vol. 38 (2), pp. 81-88. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*administration & dosage
Nanoparticles/*administration & dosage
Neoplasms/*drug therapy
Oligopeptides/*administration & dosage
Photosensitizing Agents/*administration & dosage
Porphyrins/*administration & dosage
Animals ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Chlorophyllides ; Drug Delivery Systems ; Drug Liberation ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Nanoparticles/analysis ; Nanoparticles/therapeutic use ; Oligopeptides/pharmacokinetics ; Oligopeptides/therapeutic use ; Photochemotherapy ; Photosensitizing Agents/pharmacokinetics ; Photosensitizing Agents/therapeutic use ; Porphyrins/pharmacokinetics ; Porphyrins/therapeutic use ; Rats, Sprague-Dawley ; Rats
Czasopismo naukowe
Tytuł:
The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells.
Autorzy:
Fayad C; Natural Sciences Department, Lebanese American University, Byblos, Lebanon.
Audi H; Department of Natural Sciences, Lebanese American University, Chouran, Beirut, Lebanon.
Khnayzer RS; Department of Natural Sciences, Lebanese American University, Chouran, Beirut, Lebanon. .
Daher CF; Natural Sciences Department, Lebanese American University, Byblos, Lebanon. .
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Źródło:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry [J Biol Inorg Chem] 2021 Feb; Vol. 26 (1), pp. 43-55. Date of Electronic Publication: 2020 Nov 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Carcinoma, Non-Small-Cell Lung/*drug therapy
Coordination Complexes/*pharmacology
Lung Neoplasms/*drug therapy
Photosensitizing Agents/*pharmacology
Triple Negative Breast Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/radiation effects ; Antineoplastic Agents/toxicity ; Apoptosis/drug effects ; Cell Line, Tumor ; Coordination Complexes/radiation effects ; Coordination Complexes/toxicity ; Humans ; Light ; Mesenchymal Stem Cells/drug effects ; Photosensitizing Agents/radiation effects ; Photosensitizing Agents/toxicity ; Pyridines/pharmacology ; Pyridines/radiation effects ; Pyridines/toxicity ; Rats ; Reactive Oxygen Species/metabolism ; Ruthenium/chemistry ; Ruthenium/toxicity
Czasopismo naukowe
Tytuł:
Chemical approaches for the enhancement of porphyrin skeleton-based photodynamic therapy.
Autorzy:
Lin Y; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, China.
Zhou T; School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, China.
Bai R; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Xie Y; Collaborative Innovation Centre of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, China.; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 1080-1099.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Photochemotherapy*
Antineoplastic Agents/*pharmacology
Neoplasms/*drug therapy
Photosensitizing Agents/*pharmacology
Porphyrins/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Proliferation/drug effects ; Drug Design ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Neoplasms/pathology ; Photosensitizing Agents/chemical synthesis ; Photosensitizing Agents/chemistry ; Porphyrins/chemical synthesis ; Porphyrins/chemistry
Czasopismo naukowe
Tytuł:
Near-Infrared Hypocrellin Derivatives for Synergistic Photodynamic and Photothermal Therapy.
Autorzy:
Ding Y; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Liu W; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Wu J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Zheng X; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Ge J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Ren H; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Zhang W; Center Of Super-Diamond and Advanced Films (COSDAF) & Department of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, P. R. China.
Lee CS; Center Of Super-Diamond and Advanced Films (COSDAF) & Department of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, P. R. China.
Wang P; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
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Źródło:
Chemistry, an Asian journal [Chem Asian J] 2020 Nov 02; Vol. 15 (21), pp. 3462-3468. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Photothermal Therapy*
Antineoplastic Agents/*pharmacology
Perylene/*analogs & derivatives
Phenol/*pharmacology
Photosensitizing Agents/*pharmacology
Quinones/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Survival/drug effects ; Female ; Infrared Rays ; Mammary Neoplasms, Experimental/diagnostic imaging ; Mammary Neoplasms, Experimental/drug therapy ; Mice ; Optical Imaging ; Perylene/chemical synthesis ; Perylene/chemistry ; Perylene/pharmacology ; Phenol/chemical synthesis ; Phenol/chemistry ; Photosensitizing Agents/chemical synthesis ; Photosensitizing Agents/chemistry ; Quinones/chemical synthesis ; Quinones/chemistry ; Theranostic Nanomedicine
Czasopismo naukowe

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