Autor: "Picardo SL" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Structure and Optimization of Checkpoint Inhibitors.
Autorzy:: Picardo SL; Department of Medical Oncology, Princess Margaret Cancer Centre, 700 University Avenue, Toronto, ON M5G 1X6, Canada.
Doi J; Department of Pharmacy, Princess Margaret Cancer Centre, 610 University Avenue, Toronto, ON M5G 2M9, Canada.
Hansen AR; Department of Medical Oncology, Princess Margaret Cancer Centre, 700 University Avenue, Toronto, ON M5G 1X6, Canada.; Pokaż więcej
Źródło:: Cancers [Cancers (Basel)] 2019 Dec 21; Vol. 12 (1). Date of Electronic Publication: 2019 Dec 21.
Typ publikacji:: Journal Article; Review

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Tytuł:: Differential Expression Profiles of Oxidative Stress Levels, 8-oxo-dG and 4-HNE, in Barrett's Esophagus Compared to Esophageal Adenocarcinoma.
Autorzy:: O'Farrell NJ; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James' Hospital, Dublin 8, Ireland.
Phelan JJ; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James' Hospital, Dublin 8, Ireland.
Feighery R; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James' Hospital, Dublin 8, Ireland.
Doyle B; Department of Histopathology, St. James' Hospital, Dublin 8, Ireland.
Picardo SL; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James' Hospital, Dublin 8, Ireland.
Ravi N; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James' Hospital, Dublin 8, Ireland.
O'Toole D; Department of Clinical Medicine, Trinity Translational Medicine Institute, St. James' Hospital, Dublin 8, Ireland.
Reynolds JV; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James' Hospital, Dublin 8, Ireland.
O'Sullivan J; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James' Hospital, Dublin 8, Ireland. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Sep 10; Vol. 20 (18). Date of Electronic Publication: 2019 Sep 10.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Oxidative Stress*
Transcriptome*
8-Hydroxy-2'-Deoxyguanosine/*metabolism
Adenocarcinoma/*genetics
Aldehydes/*metabolism
Barrett Esophagus/*genetics
Esophageal Neoplasms/*genetics
Adenocarcinoma/diagnosis ; Adenocarcinoma/metabolism ; Adult ; Aged ; Aged, 80 and over ; Apoptosis/genetics ; Barrett Esophagus/diagnosis ; Barrett Esophagus/metabolism ; Cell Proliferation/genetics ; Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged

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Tytuł:: Changes in mitochondrial stability during the progression of the Barrett's esophagus disease sequence.
Autorzy:: O'Farrell NJ; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
Feighery R; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
Picardo SL; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
Lynam-Lennon N; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
Biniecka M; Education and Research Centre, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
McGarrigle SA; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
Phelan JJ; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
MacCarthy F; Trinity Translational Medicine Institute, Department of Clinical Medicine, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
O'Toole D; Trinity Translational Medicine Institute, Department of Clinical Medicine, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
Fox EJ; Department of Pathology, University of Washington, Seattle, WA, 98195, USA.
Ravi N; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
Reynolds JV; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
O'Sullivan J; Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2016 Jul 19; Vol. 16, pp. 497. Date of Electronic Publication: 2016 Jul 19.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Mutation*
Adenocarcinoma/*genetics
Barrett Esophagus/*genetics
Metaplasia/*genetics
Mitochondria/*genetics
Adenocarcinoma/metabolism ; Barrett Esophagus/metabolism ; Cell Line ; Cell Line, Tumor ; Cytochromes c/metabolism ; Cytoglobin ; Cytokines/metabolism ; Disease Progression ; Enzyme-Linked Immunosorbent Assay ; Esophagus/metabolism ; Esophagus/pathology ; Globins/genetics ; Globins/metabolism ; Humans ; Inflammation Mediators/metabolism ; Metaplasia/metabolism ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Reactive Oxygen Species/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Risk Factors

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Tytuł:: A Barrett's esophagus registry of over 1000 patients from a specialist center highlights greater risk of progression than population-based registries and high risk of low grade dysplasia.
Autorzy:: Picardo SL; Department of Surgery, Trinity Center for Health Sciences, St. James's Hospital and Trinity College Dublin, Dublin, Ireland.
O'Brien MP
Feighery R
O'Toole D
Ravi N
O'Farrell NJ
O'Sullivan JN
Reynolds JV; Pokaż więcej
Źródło:: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus [Dis Esophagus] 2015 Feb-Mar; Vol. 28 (2), pp. 121-6. Date of Electronic Publication: 2014 Jan 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adenocarcinoma/*epidemiology
Barrett Esophagus/*epidemiology
Esophageal Neoplasms/*epidemiology
Registries/*statistics & numerical data
Age Distribution ; Aged ; Aged, 80 and over ; Barrett Esophagus/pathology ; Biopsy/statistics & numerical data ; Disease Progression ; Esophagus/pathology ; Female ; Humans ; Incidence ; Ireland/epidemiology ; Male ; Middle Aged ; Prospective Studies ; Risk ; Sex Distribution
SCR Disease Name:: Adenocarcinoma Of Esophagus

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