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Wyszukujesz frazę ""Pickar-Oliver, Adrian"" wg kryterium: Autor


Wyświetlanie 1-5 z 5
Tytuł :
Full-length dystrophin restoration via targeted exon integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy.
Autorzy :
Pickar-Oliver A; Department of Biomedical Engineering, Room 1427 FCIEMAS, 101 Science Drive, Box 90281, Duke University, Durham, NC 27708, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA.
Gough V; Department of Biomedical Engineering, Room 1427 FCIEMAS, 101 Science Drive, Box 90281, Duke University, Durham, NC 27708, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA.
Bohning JD; Department of Biomedical Engineering, Room 1427 FCIEMAS, 101 Science Drive, Box 90281, Duke University, Durham, NC 27708, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA.
Liu S; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA; Graduate Program in Computational Biology and Bioinformatics, Duke University, Durham, NC 27708, USA.
Robinson-Hamm JN; Department of Biomedical Engineering, Room 1427 FCIEMAS, 101 Science Drive, Box 90281, Duke University, Durham, NC 27708, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA.
Daniels H; Department of Biomedical Engineering, Room 1427 FCIEMAS, 101 Science Drive, Box 90281, Duke University, Durham, NC 27708, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA.
Majoros WH; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA; Center for Statistical Genetics and Genomics, Duke University, Durham, NC 27708, USA; Division of Integrative Genomics, Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC 27710, USA.
Devlin G; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.
Asokan A; Department of Biomedical Engineering, Room 1427 FCIEMAS, 101 Science Drive, Box 90281, Duke University, Durham, NC 27708, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA; Regeneration Next Initiative, Duke University, Durham, NC 27710, USA.
Gersbach CA; Department of Biomedical Engineering, Room 1427 FCIEMAS, 101 Science Drive, Box 90281, Duke University, Durham, NC 27708, USA; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA; Graduate Program in Computational Biology and Bioinformatics, Duke University, Durham, NC 27708, USA; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA; Regeneration Next Initiative, Duke University, Durham, NC 27710, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: .
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Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Sep 10. Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart.
Autorzy :
Walejko JM; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Christopher BA; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA.
Crown SB; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Zhang GF; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.
Pickar-Oliver A; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Yoneshiro T; UCSF Diabetes Center, San Francisco, CA, USA.
Foster MW; Duke Proteomics and Metabolomics Shared Resource, Duke University School of Medicine, Durham, NC, USA.
Page S; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
van Vliet S; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Ilkayeva O; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.
Muehlbauer MJ; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.
Carson MW; Eli Lilly and Company, Indianapolis, IN, US.
Brozinick JT; Eli Lilly and Company, Indianapolis, IN, US.
Hammond CD; Eli Lilly and Company, Indianapolis, IN, US.
Gimeno RE; Eli Lilly and Company, Indianapolis, IN, US.
Moseley MA; Duke Proteomics and Metabolomics Shared Resource, Duke University School of Medicine, Durham, NC, USA.
Kajimura S; UCSF Diabetes Center, San Francisco, CA, USA.
Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
Newgard CB; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA.; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
White PJ; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA. .; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA. .; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA. .; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA. .
McGarrah RW; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA. .; Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA. .; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 15; Vol. 12 (1), pp. 1680. Date of Electronic Publication: 2021 Mar 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acids, Branched-Chain/*metabolism
Heart/*physiology
Hemiterpenes/*metabolism
Keto Acids/*metabolism
Animals ; Male ; Mice ; Mice, Inbred C57BL ; Mitochondria/metabolism ; Obesity/metabolism ; Rats ; Valine/metabolism
Czasopismo naukowe
Tytuł :
Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo.
Autorzy :
Mao M; Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Chang CC; Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Pickar-Oliver A; Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, 27708, USA.
Cervia LD; Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Wang L; Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Ji J; Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Liton PB; Department of Ophthalmology, Duke University, Durham, NC, 27708, USA.
Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, 27708, USA.; Department of Surgery, Duke University Medical Center, Durham, NC, 27708, USA.
Yuan F; Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.; Department of Ophthalmology, Duke University, Durham, NC, 27708, USA.
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Źródło :
Advanced biosystems [Adv Biosyst] 2020 Aug; Vol. 4 (8), pp. e2000059. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Delivery Systems/*methods
Genetic Therapy/*methods
Raffinose/*pharmacology
Sucrose/*pharmacology
Trehalose/*pharmacology
Biological Transport ; CRISPR-Cas Systems ; DNA Transposable Elements ; Electroporation ; HEK293 Cells ; Humans ; Lysosomes/drug effects ; Lysosomes/metabolism ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism ; Plasmids/chemistry ; Plasmids/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Ribonucleoproteins/genetics ; Ribonucleoproteins/metabolism
Czasopismo naukowe
Tytuł :
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells.
Autorzy :
Pickar-Oliver A; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Black JB; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Lewis MM; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Mutchnick KJ; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Klann TS; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Gilcrest KA; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Sitton MJ; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Nelson CE; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
Barrera A; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.
Bartelt LC; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.
Reddy TE; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.; University Program in Genetics and Genomics, Duke University, Durham, NC, USA.
Beisel CL; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, USA.; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Centre for Infection Research (HZI), Würzburg, Germany.; Medical Faculty, University of Würzburg, Würzburg, Germany.
Barrangou R; Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC, USA.
Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, USA. .; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA. .; Department of Surgery, Duke University Medical Center, Durham, NC, USA. .
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Źródło :
Nature biotechnology [Nat Biotechnol] 2019 Dec; Vol. 37 (12), pp. 1493-1501. Date of Electronic Publication: 2019 Sep 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
CRISPR-Cas Systems/*genetics
Genetic Engineering/*methods
Transcription, Genetic/*genetics
Escherichia coli/genetics ; HEK293 Cells ; Humans ; Listeria monocytogenes/genetics ; RNA, Guide/genetics
Czasopismo naukowe
Tytuł :
The next generation of CRISPR-Cas technologies and applications.
Autorzy :
Pickar-Oliver A; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, USA. .; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA. .; Department of Surgery, Duke University Medical Center, Durham, NC, USA. .
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Źródło :
Nature reviews. Molecular cell biology [Nat Rev Mol Cell Biol] 2019 Aug; Vol. 20 (8), pp. 490-507.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
CRISPR-Cas Systems*
Clustered Regularly Interspaced Short Palindromic Repeats*
Endonucleases*/genetics
Endonucleases*/metabolism
Gene Editing*
Genetic Therapy*
RNA, Guide*/genetics
RNA, Guide*/metabolism
Animals ; Humans
Czasopismo naukowe
    Wyświetlanie 1-5 z 5

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