- Tytuł:
- Increased local cytostatic drug exposure by isolated hepatic perfusion: a phase I clinical and pharmacologic evaluation of treatment with high dose melphalan in patients with colorectal cancer confined to the liver.
- Autorzy:
- Źródło:
- British journal of cancer [Br J Cancer] 2000 May; Vol. 82 (9), pp. 1539-46.
- Typ publikacji:
- Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Chemotherapy, Cancer, Regional Perfusion*
Antineoplastic Agents, Alkylating/*administration & dosage
Colorectal Neoplasms/*drug therapy
Liver Neoplasms/*drug therapy
Melphalan/*administration & dosage
Antineoplastic Agents, Alkylating/adverse effects ; Antineoplastic Agents, Alkylating/pharmacokinetics ; Area Under Curve ; Colorectal Neoplasms/pathology ; Humans ; Liver Neoplasms/secondary ; Melphalan/adverse effects ; Melphalan/pharmacokinetics ; Survival Analysis ; Treatment Outcome
Czasopismo naukowe