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Wyszukujesz frazę ""Pioglitazone"" wg kryterium: Temat


Tytuł:
Metformin versus metformin plus pioglitazone on gonadal and metabolic profiles in normal-weight women with polycystic ovary syndrome: a single-center, open-labeled prospective randomized controlled trial.
Autorzy:
Zhao H; Department of Endocrinology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Wuxi, Jiangsu, 214000, PR China.; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China.
Zhang J; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China.
Xing C; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China.
Cheng X; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China.
He B; Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110000, PR China. .
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Źródło:
Journal of ovarian research [J Ovarian Res] 2024 Feb 19; Vol. 17 (1), pp. 42. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Metformin*/pharmacology
Metformin*/therapeutic use
Polycystic Ovary Syndrome*/drug therapy
Female ; Humans ; Pioglitazone/therapeutic use ; Prospective Studies ; Testosterone ; Luteinizing Hormone ; Follicle Stimulating Hormone ; Anti-Mullerian Hormone ; Metabolome ; Glucose
Czasopismo naukowe
Tytuł:
Drug Repositioning of Pioglitazone in Management and Improving the Cognitive Function among the Patients With Mild to Moderate Alzheimer's Disease: A Systematic Review and Meta-Analysis.
Autorzy:
Basutkar RS; Department of Pharmacy Practice, Nitte (Deemed to be University) NGSM Institute of Pharmaceutical Sciences, Mangalore, Karnataka, India.
Sudarsan P; Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, The Nilgiris, Tamil Nadu, India.
Robin SM; Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, The Nilgiris, Tamil Nadu, India.
Bhaskar V; Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, The Nilgiris, Tamil Nadu, India.
Viswanathan B; Department of Emergency Medicine, Government Medical College and Hospital, Ooty, Tamil Nadu, India.
Sivasankaran P; Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, The Nilgiris, Tamil Nadu, India.
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Źródło:
Neurology India [Neurol India] 2023 Nov-Dec; Vol. 71 (6), pp. 1132-1141.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article; Review
MeSH Terms:
Alzheimer Disease*/drug therapy
Humans ; Pioglitazone/therapeutic use ; Pioglitazone/pharmacology ; Drug Repositioning ; Cognition
Czasopismo naukowe
Tytuł:
Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets.
Autorzy:
Basagni F; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Di Paolo ML; Department of Molecular Medicine, University of Padova, Via G. Colombo 3, 35131 Padova, Italy.
Cozza G; Department of Molecular Medicine, University of Padova, Via G. Colombo 3, 35131 Padova, Italy.
Dalla Via L; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via F. Marzolo 5, 35131 Padova, Italy.; Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali (INSTM), 50121 Firenze, Italy.
Fagiani F; Department of Drug Sciences (Pharmacology Section), University of Pavia, V.le Taramelli 14, 27100 Pavia, Italy.; Division of Neuroscience, IRCCS San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy.
Lanni C; Department of Drug Sciences (Pharmacology Section), University of Pavia, V.le Taramelli 14, 27100 Pavia, Italy.
Rosini M; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Minarini A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 04; Vol. 28 (21). Date of Electronic Publication: 2023 Nov 04.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/pharmacology
Antioxidants*/metabolism
Neurodegenerative Diseases*/metabolism
Humans ; NF-E2-Related Factor 2/metabolism ; Pioglitazone/pharmacology ; Oxidative Stress ; Monoamine Oxidase/metabolism
Czasopismo naukowe
Tytuł:
Structural Identification of Impurities in Pioglitazone Hydrochloride Preparations by 2D-UHPLC-Q-Exactive Orbitrap HRMS and Their Toxicity Prediction.
Autorzy:
Zhang, Dandan (AUTHOR)
Wang, Weijian (AUTHOR)
Zhao, Haiyun (AUTHOR)
Wang, Song (AUTHOR)
Yu, Mingyan (AUTHOR)
Zhang, Dongmei (AUTHOR)
Liu, Wenkun (AUTHOR)
Xie, Qiangsheng (AUTHOR)
Chen, Dejun (AUTHOR)
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Źródło:
International Journal of Analytical Chemistry. 10/17/2023, p1-12. 12p.
Czasopismo naukowe
Tytuł:
Comparative effectiveness of multiple different treatment regimens for nonalcoholic fatty liver disease with type 2 diabetes mellitus: a systematic review and Bayesian network meta-analysis of randomised controlled trials.
Autorzy:
Deng M; Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.; Qinghai Research Key Laboratory for Echinococcosis, Xining, 810000, Qinghai, China.
Wen Y; Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.
Yan J; Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.; Department of Interventional Therapy, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.
Fan Y; Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.
Wang Z; Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.; Qinghai Research Key Laboratory for Echinococcosis, Xining, 810000, Qinghai, China.
Zhang R; Department of Endocrinology, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.
Ren L; Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.; Qinghai Research Key Laboratory for Echinococcosis, Xining, 810000, Qinghai, China.
Ba Y; Department of Nephrology, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.
Wang H; Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.; Qinghai Research Key Laboratory for Echinococcosis, Xining, 810000, Qinghai, China.
Lu Q; Department of Hepatopancreatobiliary Surgery, Tsinghua Changgung Hospital, Tsinghua University, Beijing, 102218, China. .
Fan H; Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China. .; Qinghai Research Key Laboratory for Echinococcosis, Xining, 810000, Qinghai, China. .
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Źródło:
BMC medicine [BMC Med] 2023 Nov 16; Vol. 21 (1), pp. 447. Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Systematic Review; Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*/drug therapy
Non-alcoholic Fatty Liver Disease*/drug therapy
Insulin Resistance*
Humans ; Exenatide/therapeutic use ; Hypoglycemic Agents/pharmacology ; Liraglutide/therapeutic use ; Network Meta-Analysis ; Pioglitazone/therapeutic use ; Bayes Theorem
Czasopismo naukowe
Tytuł:
A gut microbial metabolite of linoleic acid ameliorates liver fibrosis by inhibiting TGF-β signaling in hepatic stellate cells.
Autorzy:
Kasahara N; Laboratory of Nutritional Physiology, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-Ku, Shizuoka, 422-8526, Japan.
Imi Y; Laboratory of Nutritional Physiology, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-Ku, Shizuoka, 422-8526, Japan.
Amano R; Laboratory of Nutritional Physiology, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-Ku, Shizuoka, 422-8526, Japan.
Shinohara M; Division of Molecular Epidemiology, Department of Future Medicine Sciences, Kobe University Graduate School of Medicine, Kobe, Hyogo, 650-0017, Japan.; The Integrated Center for Mass Spectrometry, Kobe University Graduate School of Medicine, Kobe, Hyogo, 650-0017, Japan.
Okada K; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, 650-0017, Japan.
Hosokawa Y; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, 650-0017, Japan.
Imamori M; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, 650-0017, Japan.
Tomimoto C; Noster Inc., Muko-Shi, Kyoto, 617-0006, Japan.
Kunisawa J; Laboratory of Vaccine Materials and Laboratory of Gut Environmental System, Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN), Osaka, 567-0085, Japan.
Kishino S; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-Ku, Kyoto, 606-8502, Japan.
Ogawa J; Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Sakyo-Ku, Kyoto, 606-8502, Japan.
Ogawa W; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, 650-0017, Japan.
Hosooka T; Laboratory of Nutritional Physiology, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-Ku, Shizuoka, 422-8526, Japan. .; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, 650-0017, Japan. .; Laboratory of Vaccine Materials and Laboratory of Gut Environmental System, Microbial Research Center for Health and Medicine, National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN), Osaka, 567-0085, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 03; Vol. 13 (1), pp. 18983. Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/pathology
Gastrointestinal Microbiome*
Mice ; Humans ; Animals ; Pioglitazone/pharmacology ; Linoleic Acid/metabolism ; Hepatic Stellate Cells/metabolism ; Mice, Inbred C57BL ; Liver/metabolism ; Liver Cirrhosis/pathology ; Fibrosis ; Diet, High-Fat/adverse effects ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł:
Pioglitazone Protects Tubular Epithelial Cells during Kidney Fibrosis by Attenuating miRNA Dysregulation and Autophagy Dysfunction Induced by TGF-β.
Autorzy:
Manzéger A; Institute of Translational Medicine, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, Hungary.; International Nephrology Research and Training Center, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, Hungary.
Garmaa G; Institute of Translational Medicine, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, Hungary.
Mózes MM; Institute of Translational Medicine, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, Hungary.; International Nephrology Research and Training Center, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, Hungary.
Hansmann G; Department of Pediatric Cardiology and Critical Care, Hannover Medical School, 30625 Hannover, Germany.
Kökény G; Institute of Translational Medicine, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, Hungary.; International Nephrology Research and Training Center, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 24; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
Kidney Diseases*/drug therapy
Kidney Diseases*/etiology
Kidney Diseases*/metabolism
Male ; Mice ; Animals ; Pioglitazone/pharmacology ; Transforming Growth Factor beta/metabolism ; Kidney/metabolism ; Transforming Growth Factor beta1/metabolism ; RNA, Messenger/genetics ; Fibrosis ; Autophagy ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
The antidiabetic drug pioglitazone ameliorates betel-nut-induced carcinogenesis in mice by restoring normal lipid metabolism, reducing oxidative stress, and inducing apoptosis.
Autorzy:
Nath M; Department of Biotechnology, Assam University, Silchar, Assam, India.
Bhattacharjee K
Choudhury Y
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Oct 01; Vol. 19 (7), pp. 1967-1974. Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article
MeSH Terms:
Lipid Metabolism*
Hypoglycemic Agents*/pharmacology
Female ; Animals ; Mice ; Pioglitazone/pharmacology ; Areca ; Nuts ; Proto-Oncogene Proteins c-akt ; Oxidative Stress ; Carcinogenesis ; Apoptosis ; TOR Serine-Threonine Kinases ; Lipids
Czasopismo naukowe
Tytuł:
Regulation of Neuroinflammatory Signaling by PPARγ Agonist in Mouse Model of Diabetes.
Autorzy:
Piątkowska-Chmiel I; Chair and Department of Toxicology, Faculty of Pharmacy, Medical University of Lublin, Jaczewskiego 8b Street, 20-090 Lublin, Poland.
Herbet M; Chair and Department of Toxicology, Faculty of Pharmacy, Medical University of Lublin, Jaczewskiego 8b Street, 20-090 Lublin, Poland.
Gawrońska-Grzywacz M; Chair and Department of Toxicology, Faculty of Pharmacy, Medical University of Lublin, Jaczewskiego 8b Street, 20-090 Lublin, Poland.
Dudka J; Chair and Department of Toxicology, Faculty of Pharmacy, Medical University of Lublin, Jaczewskiego 8b Street, 20-090 Lublin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 14; Vol. 23 (10). Date of Electronic Publication: 2022 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/drug therapy
Neuroinflammatory Diseases*/etiology
Neuroinflammatory Diseases*/prevention & control
PPAR gamma*/agonists
Pioglitazone*/pharmacology
Pioglitazone*/therapeutic use
Animals ; Caveolin 1/metabolism ; Disease Models, Animal ; Interleukin-6/metabolism ; Mice ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Age-associated sex difference in the expression of mitochondria-based redox sensitive proteins and effect of pioglitazone in nonhuman primate brain.
Autorzy:
Jamwal S; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Blackburn JK; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Elsworth JD; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. .
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Źródło:
Biology of sex differences [Biol Sex Differ] 2023 Sep 28; Vol. 14 (1), pp. 65. Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Sex Characteristics*
Brain*/metabolism
Animals ; Female ; Male ; Chlorocebus aethiops ; Pioglitazone/pharmacology ; Pioglitazone/metabolism ; Protein Isoforms/metabolism ; Protein Isoforms/pharmacology ; Mitochondria ; Oxidation-Reduction
Czasopismo naukowe
Tytuł:
Effect of Empagliflozin and Pioglitazone on left ventricular function in patients with type two diabetes and nonalcoholic fatty liver disease without established cardiovascular disease: a randomized single-blind clinical trial.
Autorzy:
Attaran F; Endocrine Research Center, Institute of Endocrinology and Metabolism, Department of Internal Medicine, School of Medicine, Iran University of Medical Science, No. 10, Firoozeh St., Vali-asr Ave., Vali-asr Sq, Tehran, Iran.
Emami S; Department of Cardiology, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Sohrabi M; Gastrointestinal and liver diseases research center, Iran University of Medical Sciences, Tehran, Iran.
Malek M; Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran.
Ajdarkosh H; Gastrointestinal and liver diseases research center, Iran University of Medical Sciences, Tehran, Iran.
Khoonsari M; Gastrointestinal and liver diseases research center, Iran University of Medical Sciences, Tehran, Iran.
Ismail-Beigi F; School of Medicine, Case Western Reserve University, Cleveland, USA.
Khamseh ME; Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Science, Tehran, Iran. .
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Źródło:
BMC gastroenterology [BMC Gastroenterol] 2023 Sep 23; Vol. 23 (1), pp. 327. Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/complications
Non-alcoholic Fatty Liver Disease*/diagnostic imaging
Non-alcoholic Fatty Liver Disease*/drug therapy
Cardiovascular Diseases*/etiology
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Humans ; Pioglitazone/therapeutic use ; Ventricular Function, Left ; Iran ; Single-Blind Method
Czasopismo naukowe
Tytuł:
SPIOMET4HEALTH-efficacy, tolerability and safety of lifestyle intervention plus a fixed dose combination of spironolactone, pioglitazone and metformin (SPIOMET) for adolescent girls and young women with polycystic ovary syndrome: study protocol for a multicentre, randomised, double-blind, placebo-controlled, four-arm, parallel-group, phase II clinical trial.
Autorzy:
Garcia-Beltran C; Paediatric Endocrinology, Paediatric Research Institute Sant Joan de Déu, University of Barcelona, 08950, Esplugues, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), ISCIII, Madrid, 28029, Spain.
Malpique R; Paediatric Endocrinology, Paediatric Research Institute Sant Joan de Déu, University of Barcelona, 08950, Esplugues, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), ISCIII, Madrid, 28029, Spain.
Andersen MS; Department of Gynaecology and Obstetrics and Department of Endocrinology, University of Southern Denmark, Odense University Hospital, Odense, Denmark.
Bas F; Pediatric Endocrinology Unit, Istanbul University, Istanbul, Turkey.
Bassols J; Maternal-Fetal Metabolic Research Group, Girona Institute for Biomedical Research (IDIBGI), Girona, Spain.
Darendeliler F; Pediatric Endocrinology Unit, Istanbul University, Istanbul, Turkey.
Díaz M; Paediatric Endocrinology, Paediatric Research Institute Sant Joan de Déu, University of Barcelona, 08950, Esplugues, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), ISCIII, Madrid, 28029, Spain.
Dieris B; Department of Paediatric Endocrinology, Diabetes and Nutrition Medicine, Vestische Hospital for Children and Adolescents Datteln, University of Witten-Herdecke, Datteln, Germany.
Fanelli F; Department of Medical and Surgical Science-DIMEC, Division of Endocrinology and Diabetes Prevention and Care, University of Bologna - S. Orsola-Hospital, Bologna, Italy.
Fröhlich-Reiterer E; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Gambineri A; Department of Medical and Surgical Science-DIMEC, Division of Endocrinology and Diabetes Prevention and Care, University of Bologna - S. Orsola-Hospital, Bologna, Italy.
Glintborg D; Department of Gynaecology and Obstetrics and Department of Endocrinology, University of Southern Denmark, Odense University Hospital, Odense, Denmark.
López-Bermejo A; Paediatric Endocrinology Research Group, Girona Institute for Biomedical Research (IDIBGI), Paediatrics, Dr. Josep Trueta Hospital, Department of Medical Sciences, University of Girona, Girona, Spain.
Mann C; Asphalion, Barcelona, Spain.
Marin S; Paediatric Endocrinology, Paediatric Research Institute Sant Joan de Déu, University of Barcelona, 08950, Esplugues, Barcelona, Spain.
Obermayer-Pietsch B; Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Ødegård R; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Centre for Obesity Research, St. Olavs Hospital, Trondheim University Hospital, Torgarden, Trondheim, Norway.
Ravn P; Department of Gynaecology and Obstetrics and Department of Endocrinology, University of Southern Denmark, Odense University Hospital, Odense, Denmark.
Reinehr T; Department of Paediatric Endocrinology, Diabetes and Nutrition Medicine, Vestische Hospital for Children and Adolescents Datteln, University of Witten-Herdecke, Datteln, Germany.
Renzulli M; Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Salvador C; Paediatric Endocrinology, Paediatric Research Institute Sant Joan de Déu, University of Barcelona, 08950, Esplugues, Barcelona, Spain.
Singer V; Department of Paediatric Endocrinology, Diabetes and Nutrition Medicine, Vestische Hospital for Children and Adolescents Datteln, University of Witten-Herdecke, Datteln, Germany.
Vanky E; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Obstetrics and Gynaecology, St. Olavs Hospital, Trondheim University Hospital, 7006, Trondheim, Norway.
Torres JV; Optimapharm, Palma de Mallorca, Palma, Spain.
Yildiz M; Pediatric Endocrinology Unit, Istanbul University, Istanbul, Turkey.
de Zegher F; Leuven Research & Development, University of Leuven, 3000, Louvain, Belgium.
Ibáñez L; Paediatric Endocrinology, Paediatric Research Institute Sant Joan de Déu, University of Barcelona, 08950, Esplugues, Barcelona, Spain. .; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), ISCIII, Madrid, 28029, Spain. .
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Źródło:
Trials [Trials] 2023 Sep 15; Vol. 24 (1), pp. 589. Date of Electronic Publication: 2023 Sep 15.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Metformin*/adverse effects
Polycystic Ovary Syndrome*/diagnosis
Polycystic Ovary Syndrome*/drug therapy
Adolescent ; Female ; Humans ; Carotid Intima-Media Thickness ; Clinical Trials, Phase II as Topic ; Insulin ; Life Style ; Multicenter Studies as Topic ; Pioglitazone/adverse effects ; Quality of Life ; Randomized Controlled Trials as Topic ; Spironolactone ; Young Adult
Czasopismo naukowe
Tytuł:
PPARG stimulation restored lung mRNA expression of core clock, inflammation- and metabolism-related genes disrupted by reversed feeding in male mice.
Autorzy:
Shlykova O; Poltava State Medical University, Poltava, Ukraine.
Izmailova O; Poltava State Medical University, Poltava, Ukraine.
Kabaliei A; Poltava State Medical University, Poltava, Ukraine.
Palchyk V; Poltava State Medical University, Poltava, Ukraine.
Shynkevych V; Poltava State Medical University, Poltava, Ukraine.
Kaidashev I; Poltava State Medical University, Poltava, Ukraine.
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Źródło:
Physiological reports [Physiol Rep] 2023 Sep; Vol. 11 (17), pp. e15823.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
PPAR gamma*/genetics
Tumor Necrosis Factor-alpha*
Animals ; Male ; Mice ; Dimercaprol ; Inflammation/genetics ; Interleukin-6 ; Lung ; Pioglitazone/pharmacology ; RNA, Messenger
Czasopismo naukowe
Tytuł:
Combination of Pioglitazone and Metformin Actions on Liver Lipid Metabolism in Obese Mice.
Autorzy:
Liu J; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.; Department of Medical Research Center, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Wang D; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Xie Z; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Ding L; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Li S; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Ma X; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Liu J; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Ren J; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Xiao C; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Yang C; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Xiao X; Department of Endocrinology, NHC Key Laboratory of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
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Źródło:
Biomolecules [Biomolecules] 2023 Jul 31; Vol. 13 (8). Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lipid Metabolism*
Non-alcoholic Fatty Liver Disease*/drug therapy
Male ; Animals ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Pioglitazone/pharmacology
Czasopismo naukowe
Tytuł:
Implications of Pharmacokinetic Potentials of Pioglitazone Enantiomers in Rat Plasma Mediated through Glucose Uptake Assay.
Autorzy:
Spandana, Tatineni (AUTHOR)
Goli, Veera Venkata Nishanth (AUTHOR)
Rahamathulla, Mohamed (AUTHOR)
Talath, Sirajunisa (AUTHOR)
Osmani, Riyaz Ali M. (AUTHOR)
Ahmed, Mohammed Muqtader (AUTHOR)
Farhana, Syeda Ayesha (AUTHOR)
Hussain, Shalam Mohamed (AUTHOR)
Gurupadayya, Bannimath (AUTHOR)
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Źródło:
Molecules. Jul2023, Vol. 28 Issue 13, p4911. 14p.
Czasopismo naukowe
Tytuł:
PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis.
Autorzy:
Xue X; Department of Orthopedics, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Dai T; Guangzhou Institute of Traumatic Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Chen J; Guizhou Medical University, Guiyang, China.
Xu Y; Guizhou Medical University, Guiyang, China.
Yang Z; Department of Orthopedics, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Huang J; Department of Traumatic Orthopedics, The Central Hospital of Xiaogan, Xiaogan, China.
Xu W; Department of Orthopedics, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China.
Li S; Guangzhou Institute of Traumatic Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. .
Meng Q; Guangzhou Institute of Traumatic Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2023 Aug 24; Vol. 18 (1), pp. 620. Date of Electronic Publication: 2023 Aug 24.
Typ publikacji:
Journal Article
MeSH Terms:
Ferroptosis*
Mitophagy*
Osteoarthritis, Knee*
PPAR gamma*/metabolism
Animals ; Rats ; Chondrocytes ; Pioglitazone/pharmacology ; Protein Kinases
Czasopismo naukowe
Tytuł:
Different sites of actions make different responses to thiazolidinediones between mouse and rat models of fatty liver.
Autorzy:
Ebihara C; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Aizawa-Abe M; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Zhao M; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Gumbilai V; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ebihara K; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan. .; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan. .; Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 10; Vol. 12 (1), pp. 449. Date of Electronic Publication: 2022 Jan 10.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fatty Liver/*drug therapy
Lipid Metabolism/*drug effects
PPAR gamma/*metabolism
Pioglitazone/*therapeutic use
Thiazolidinediones/*therapeutic use
Animals ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Fatty Liver/etiology ; Fatty Liver/metabolism ; Leptin/deficiency ; Lipodystrophy/complications ; Male ; Mice, Inbred C57BL ; Obesity/complications ; PPAR gamma/agonists ; Pioglitazone/pharmacology ; Rats, Transgenic ; Thiazolidinediones/pharmacology ; Mice ; Rats
Czasopismo naukowe
Tytuł:
Long-Term Pioglitazone Treatment Has No Significant Impact on Microglial Activation and Tau Pathology in P301S Mice.
Autorzy:
Kunze LH; Department of Nuclear Medicine, University Hospital of LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE) Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany.
Ruch F; Department of Nuclear Medicine, University Hospital of LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Biechele G; Department of Radiology, University Hospital of LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Eckenweber F; Department of Nuclear Medicine, University Hospital of LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Wind-Mark K; Department of Nuclear Medicine, University Hospital of LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE) Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany.
Dinkel L; German Center for Neurodegenerative Diseases (DZNE) Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany.
Feyen P; German Center for Neurodegenerative Diseases (DZNE) Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany.
Bartenstein P; Department of Nuclear Medicine, University Hospital of LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Ludwig Maximilian University of Munich, 81377 Munich, Germany.
Ziegler S; Department of Nuclear Medicine, University Hospital of LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Paeger L; German Center for Neurodegenerative Diseases (DZNE) Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany.
Tahirovic S; German Center for Neurodegenerative Diseases (DZNE) Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany.
Herms J; German Center for Neurodegenerative Diseases (DZNE) Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Ludwig Maximilian University of Munich, 81377 Munich, Germany.; Center for Neuropathology and Prion Research, LMU Munich, Feodor-Lynen-Str. 23, 81377 Munich, Germany.
Brendel M; Department of Nuclear Medicine, University Hospital of LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE) Munich, Feodor-Lynen-Str. 17, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Ludwig Maximilian University of Munich, 81377 Munich, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 14; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 14.
Typ publikacji:
Journal Article
MeSH Terms:
Tauopathies*/metabolism
Alzheimer Disease*/metabolism
Mice ; Animals ; Pioglitazone/pharmacology ; Microglia/metabolism ; Amyloid beta-Peptides/metabolism ; PPAR gamma/metabolism ; Mice, Transgenic ; tau Proteins/metabolism ; Disease Models, Animal
Czasopismo naukowe

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