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Tytuł:
Tofacitinib as a biologic response modifier in VEXAS syndrome: A case series.
Autorzy:
Salehi T; Central Adelaide Local Health Network, Adelaide, South Australia, Australia.
Callisto A; Central Adelaide Local Health Network, Adelaide, South Australia, Australia.; Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.
Beecher MB; Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.
Hissaria P; Central Adelaide Local Health Network, Adelaide, South Australia, Australia.; Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.
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Źródło:
International journal of rheumatic diseases [Int J Rheum Dis] 2023 Nov; Vol. 26 (11), pp. 2340-2343. Date of Electronic Publication: 2023 Jun 19.
Typ publikacji:
Letter
MeSH Terms:
Piperidines*/adverse effects
Pyrimidines*/adverse effects
Humans ; Immunologic Factors ; Mutation
SCR Disease Name:
VEXAS syndrome
Opinia redakcyjna
Szczegóły
Tytuł:
Atogepant, the first oral preventive treatment for chronic migraine.
Autorzy:
Haanes KA; Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet-Glostrup, 2600 Glostrup, Denmark. Electronic address: .
Edvinsson L; Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet-Glostrup, 2600 Glostrup, Denmark; Department of Internal Medicine, Lund University Hospital, Lund, Sweden.
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Źródło:
Lancet (London, England) [Lancet] 2023 Sep 02; Vol. 402 (10404), pp. 748-749. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Piperidines*/therapeutic use
Migraine Disorders*/drug therapy
Migraine Disorders*/prevention & control
Humans ; Calcitonin Gene-Related Peptide ; Administration, Oral
Czasopismo naukowe
Szczegóły
Tytuł:
Fetal, Preterm, and Term Neonate Exposure to Remifentanil: A Systematic Review of Efficacy and Safety.
Autorzy:
Maroni A; Pediatric Intensive Care Unit, Robert Debré University Hospital, APHP, 75019, Paris, France.
Aubelle MS; Department of Neonatal Medicine, Cochin-Port Royal Hospital, APHP, 75014, Paris, France.
Chollat C; Department of Neonatal Paediatrics, Trousseau Hospital, APHP, Sorbonne Université, 26 Av. du Dr Arnold Netter, 75012, Paris, France. .; Université Paris Cité, Inserm, NeuroDiderot, 75019, Paris, France. .
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Źródło:
Paediatric drugs [Paediatr Drugs] 2023 Sep; Vol. 25 (5), pp. 537-555. Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:
Systematic Review
MeSH Terms:
Piperidines*/adverse effects
Analgesics, Opioid*/adverse effects
Infant, Newborn ; Humans ; Pregnancy ; Female ; Remifentanil/adverse effects ; Cesarean Section ; Prospective Studies ; Fetus ; Pain/drug therapy
Szczegóły
Tytuł:
Preclinical pharmacokinetics and metabolism study of SCO-267, a GPR40 full agonist, in beagle dogs using ultra-high performance liquid chromatography coupled to tandem mass spectrometry.
Autorzy:
Li H; Shenzhen Pingle Orthopaedic Hospital (Shenzhen Pingshan Traditional Chinese Medicine Hospital), Shenzhen, Guangdong Province, China.
Liu Y; Shenzhen Pingle Orthopaedic Hospital (Shenzhen Pingshan Traditional Chinese Medicine Hospital), Shenzhen, Guangdong Province, China.
Xiao J; Shenzhen Pingle Orthopaedic Hospital (Shenzhen Pingshan Traditional Chinese Medicine Hospital), Shenzhen, Guangdong Province, China.
Huang J; Shenzhen Pingle Orthopaedic Hospital (Shenzhen Pingshan Traditional Chinese Medicine Hospital), Shenzhen, Guangdong Province, China.
Zhang Y; Shenzhen Pingle Orthopaedic Hospital (Shenzhen Pingshan Traditional Chinese Medicine Hospital), Shenzhen, Guangdong Province, China.
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Źródło:
Biomedical chromatography : BMC [Biomed Chromatogr] 2023 Sep; Vol. 37 (9), pp. e5685. Date of Electronic Publication: 2023 May 26.
Typ publikacji:
Journal Article
MeSH Terms:
Tandem Mass Spectrometry*/methods
Piperidines*
Dogs ; Animals ; Chromatography, High Pressure Liquid/methods ; Biological Availability ; Reproducibility of Results
Czasopismo naukowe
Szczegóły
Tytuł:
Assessment of the physical dependence potential of difelikefalin: Randomized placebo-controlled study in patients receiving hemodialysis.
Autorzy:
Spencer RH; Cara Therapeutics, Inc., Stamford, Connecticut, USA.
Munera C; Cara Therapeutics, Inc., Stamford, Connecticut, USA.
Shram MJ; Altreos Research Partners, Inc., Toronto, Ontario, Canada.
Menzaghi F; Cara Therapeutics, Inc., Stamford, Connecticut, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2023 Sep; Vol. 16 (9), pp. 1559-1568. Date of Electronic Publication: 2023 May 12.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Piperidines*
Renal Dialysis*
Female ; Male ; Double-Blind Method ; Sleep ; Treatment Outcome ; Humans ; Adult ; Middle Aged ; Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Patient-reported migraine-specific quality of life, activity impairment and headache impact with once-daily atogepant for preventive treatment of migraine in a randomized, 52-week trial.
Autorzy:
Lipton RB; Albert Einstein College of Medicine, Bronx, NY, USA.
Halker Singh RB; Mayo Clinic, Scottsdale, AZ, USA.
Mechtler L; Dent Neurologic Institute, Buffalo, NY, USA.
McVige J; Dent Neurologic Institute, Buffalo, NY, USA.
Ma J; AbbVie, Madison, NJ, USA.
Yu SY; AbbVie, Irvine, CA, USA.
Stokes J; AbbVie, Madison, NJ, USA.
Dabruzzo B; AbbVie, Madison, NJ, USA.
Gandhi P; AbbVie, Madison, NJ, USA.
Ashina M; Danish Headache Center, Rigshospitalet Glostrup, University of Copenhagen, Denmark.
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Źródło:
Cephalalgia : an international journal of headache [Cephalalgia] 2023 Aug; Vol. 51 (8), pp. 3331024231190296.
Typ publikacji:
Randomized Controlled Trial; Multicenter Study; Journal Article
MeSH Terms:
Quality of Life*
Piperidines*/administration & dosage
Piperidines*/therapeutic use
Pyridines*/administration & dosage
Pyridines*/therapeutic use
Pyrroles*/administration & dosage
Pyrroles*/therapeutic use
Spiro Compounds*/administration & dosage
Spiro Compounds*/therapeutic use
Calcitonin Gene-Related Peptide Receptor Antagonists*/administration & dosage
Calcitonin Gene-Related Peptide Receptor Antagonists*/therapeutic use
Migraine Disorders*/prevention & control
Humans ; Patient Reported Outcome Measures ; Drug Administration Schedule
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pitolisant: Pediatric First Approval.
Autorzy:
Keam SJ; Springer Nature, Private Bag 65901, Mairangi Bay, Auckland, 0754, New Zealand. .
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Źródło:
Paediatric drugs [Paediatr Drugs] 2023 Jul; Vol. 25 (4), pp. 483-488. Date of Electronic Publication: 2023 May 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cataplexy*/drug therapy
Narcolepsy*/drug therapy
Piperidines*/adverse effects
Piperidines*/therapeutic use
Adolescent ; Adult ; Child ; Humans ; Drug Inverse Agonism ; Histamine Agonists/adverse effects ; Pyrazoles/therapeutic use
Czasopismo naukowe
Szczegóły
Tytuł:
Use of tofacitinib in recalcitrant cases of chronic pruritus of unknown origin.
Autorzy:
Sardana K; Department of Dermatology, Venereology and Leprosy, Atal Bihari Vajpayee Institute of Medical Sciences and Research Institute and Dr. Ram Manohar Lohia Hospital, New Delhi, India. .
Sharath S; Department of Dermatology, Venereology and Leprosy, Atal Bihari Vajpayee Institute of Medical Sciences and Research Institute and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Khurana A; Department of Dermatology, Venereology and Leprosy, Atal Bihari Vajpayee Institute of Medical Sciences and Research Institute and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
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Źródło:
Archives of dermatological research [Arch Dermatol Res] 2023 Dec; Vol. 315 (10), pp. 2955-2957. Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:
Journal Article
MeSH Terms:
Pruritus*/drug therapy
Piperidines*/therapeutic use
Humans ; Pyrimidines/therapeutic use
Czasopismo naukowe
Szczegóły
Tytuł:
Forensic toxicokinetics of difenidol hydrochloride in vivo verified by practical lethal cases.
Autorzy:
Niu W; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China.; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China.; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China.
Ren T; Institute of Forensic Science of Tianjin Public Security Bureau, Tianjin, 300384, People's Republic of China.
Wang Y; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China.; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China.; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China.
Wang Z; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China.; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China.; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China.
Zhang C; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China.; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China.; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China.
Jia J; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China.; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China.; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China.
Wei Z; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China.; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China.; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China.
Su H; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China.; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China.; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China.
Guo Z; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China.; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China.; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China.
Guo X; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China.; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China.; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China.
Yun K; School of Forensic Medicine, Shanxi Medical University, Jinzhong, 030600, Shanxi, People's Republic of China. .; Shanxi Key Laboratory of Forensic Medicine, Jinzhong, 030600, Shanxi, People's Republic of China. .; Key Laboratory of Forensic Toxicology of Ministry of Public Security, Jinzhong, 030600, Shanxi, People's Republic of China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 11; Vol. 13 (1), pp. 11190. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Forensic Medicine*
Piperidines*/toxicity
Animals ; Rats ; Toxicokinetics ; Autopsy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mild Installation of Piperidines on 4-Alkylpyridines.
Autorzy:
Shi J; Department of Chemistry, York University, 4700 Keele Street, Toronto, ON M3J 1P3, Canada!
Rasheed F; Department of Chemistry, York University, 4700 Keele Street, Toronto, ON M3J 1P3, Canada!
Fishlock D; Roche Pharma Research and Early Development, pCMC Drug Substance, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, CH-4070 Basel, Switzerland.
Orellana A; Department of Chemistry, York University, 4700 Keele Street, Toronto, ON M3J 1P3, Canada!
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Źródło:
Organic letters [Org Lett] 2023 Jul 07; Vol. 25 (26), pp. 4852-4856. Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Piperidines*
Amines*
Indicators and Reagents ; Cyclization ; Hydrogenation ; Molecular Structure
Czasopismo naukowe
Szczegóły
Tytuł:
A molecularly imprinted polymer-based electrochemical sensor for the determination of tofacitinib.
Autorzy:
Budak F; Faculty of Pharmacy, Department of Analytical Chemistry, Ankara University, Ankara, Türkiye.; Graduate School of Health Sciences, Ankara University, Ankara, Türkiye.
Cetinkaya A; Faculty of Pharmacy, Department of Analytical Chemistry, Ankara University, Ankara, Türkiye.; Graduate School of Health Sciences, Ankara University, Ankara, Türkiye.
Kaya SI; Gulhane Faculty of Pharmacy, Department of Analytical Chemistry, University of Health Sciences, Ankara, Türkiye. .
Atici EB; DEVA Holding A.S., R&D Center, Tekirdag, Türkiye.
Ozkan SA; Faculty of Pharmacy, Department of Analytical Chemistry, Ankara University, Ankara, Türkiye. .
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Źródło:
Mikrochimica acta [Mikrochim Acta] 2023 May 10; Vol. 190 (6), pp. 205. Date of Electronic Publication: 2023 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Molecularly Imprinted Polymers*
Piperidines*
Polymers ; Acrylamide
Czasopismo naukowe
Szczegóły
Tytuł:
Effective dose of remimazolam co-administered with remifentanil to facilitate I-gel insertion without neuromuscular blocking agents: an up-and-down sequential allocation trial.
Autorzy:
Oh J; Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, 164 Worldcup-Ro, Yeongtong-Gu, Suwon, 16499, Republic of Korea.
Park SY; Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, 164 Worldcup-Ro, Yeongtong-Gu, Suwon, 16499, Republic of Korea.
Lee GY; Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, 164 Worldcup-Ro, Yeongtong-Gu, Suwon, 16499, Republic of Korea.
Park JH; Office of Biostatics, Medical Research Collaborating Center, Ajou Research Institute for Innovative Medicine, Ajou University Medical Center, Suwon, Republic of Korea.
Joe HB; Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, 164 Worldcup-Ro, Yeongtong-Gu, Suwon, 16499, Republic of Korea. .
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Źródło:
BMC anesthesiology [BMC Anesthesiol] 2023 Mar 16; Vol. 23 (1), pp. 81. Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
Neuromuscular Blocking Agents*
Piperidines*
Adult ; Humans ; Anesthesia, General ; Remifentanil
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel spiro[chromanone-2,4'-piperidine]-4-one derivatives as potential inhibitors of fatty acid synthesis in pathogens: Design, synthesis, and biological evaluation.
Autorzy:
Liu SS; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China.
Zeng D; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China.
Zhang TH; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China.
Hu JH; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China.
Yang BX; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China.
Yang J; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China.
Zhou X; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China. Electronic address: .
Wang PY; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China.
Liu LW; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China.
Wu ZB; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China.
Yang S; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2023 Mar 15; Vol. 250, pp. 115215. Date of Electronic Publication: 2023 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Bacteria*
Piperidines*
Structure-Activity Relationship ; Fatty Acids/pharmacology ; Lipids ; Anti-Bacterial Agents/chemistry ; Microbial Sensitivity Tests
Czasopismo naukowe
Szczegóły
Tytuł:
Inflammatory myofibroblastic tumor of the mesentery with a SQSTM1::ALK fusion responding to alectinib.
Autorzy:
Sunga CGG; Division of Medical Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Higgins MS; PeaceHealth Department of General and Colorectal Surgery, Bellingham, Washington, USA.
Ricciotti RW; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
Liu YJ; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
Cranmer LD; Division of Medical Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA.
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Źródło:
Cancer reports (Hoboken, N.J.) [Cancer Rep (Hoboken)] 2023 Mar; Vol. 6 (3), pp. e1792. Date of Electronic Publication: 2023 Feb 08.
Typ publikacji:
Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasm Recurrence, Local*
Piperidines*
Female ; Humans ; Adult ; Anaplastic Lymphoma Kinase/genetics ; Anaplastic Lymphoma Kinase/metabolism ; Sequestosome-1 Protein/metabolism
Raport
Szczegóły
Tytuł:
Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications.
Autorzy:
Frolov NA; N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russia.
Vereshchagin AN; N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 02; Vol. 24 (3). Date of Electronic Publication: 2023 Feb 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Piperidines*/pharmacology
Alkaloids*/pharmacology
Cyclization ; Stereoisomerism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The attenuation effect of low piperine Piper nigrum extract on doxorubicin-induced toxicity of blood chemical and immunological properties in mammary tumour rats.
Autorzy:
Saetang J; Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.; Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.; EZ-Mol-Design Laboratory, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
Tedasen A; Department of Medical Technology, School of Allied Health Sciences and Public Health, Walailak University, Thai Buri, Thailand.
Sangkhathat S; Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
Sangkaew N; Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
Dokduang S; Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
Prompat N; Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
Taraporn S; Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
Graidist P; Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 96-107.
Typ publikacji:
Journal Article
MeSH Terms:
Alkaloids/*pharmacology
Benzodioxoles/*pharmacology
Doxorubicin/*toxicity
Piper nigrum/*chemistry
Piperidines/*pharmacology
Plant Extracts/*pharmacology
Polyunsaturated Alkamides/*pharmacology
Alkaloids/administration & dosage ; Alkaloids/isolation & purification ; Animals ; Antibiotics, Antineoplastic/toxicity ; Antioxidants/administration & dosage ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Benzodioxoles/administration & dosage ; Benzodioxoles/isolation & purification ; Dose-Response Relationship, Drug ; Female ; Mammary Neoplasms, Experimental/drug therapy ; Piperidines/administration & dosage ; Piperidines/isolation & purification ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry ; Polyunsaturated Alkamides/administration & dosage ; Polyunsaturated Alkamides/isolation & purification ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors.
Autorzy:
Zhao L; Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, China.
Yang Q; Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, China.
Tang Y; Department of Clinical Pharmacy, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
You Q; Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, China.
Guo X; Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, China.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 462-471.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Design*
Kv1.5 Potassium Channel/*antagonists & inhibitors
Piperidines/*pharmacology
Potassium Channel Blockers/*pharmacology
Dose-Response Relationship, Drug ; Humans ; Kv1.5 Potassium Channel/metabolism ; Molecular Structure ; Piperidines/chemical synthesis ; Piperidines/chemistry ; Potassium Channel Blockers/chemical synthesis ; Potassium Channel Blockers/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Development of Novel Microwell-Based Spectrofluorimetry and High-Performance Liquid Chromatography with Fluorescence Detection Methods and High Throughput for Quantitation of Alectinib in Bulk Powder and Urine Samples.
Autorzy:
Almutairi HS; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Alanazi MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Darwish IA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Bakheit AH; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Alshehri MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Darwish HW; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
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Źródło:
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2023 Feb 23; Vol. 59 (3). Date of Electronic Publication: 2023 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Piperidines*
Carbazoles*
Humans ; Chromatography, High Pressure Liquid/methods ; Powders
Czasopismo naukowe
Szczegóły
Tytuł:
Ibrutinib use and adverse cardiovascular outcomes: A United States federated electronic medical records analysis.
Autorzy:
Gent DG; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom. Electronic address: .
Rivera-Caravaca JM; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom.
Dobson R; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom.
Wright DJ; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom.
Lip GYH; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom.
Pokaż więcej
Corporate Authors:
Liverpool Centre for Cardiovascular Science; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom.
Źródło:
European journal of internal medicine [Eur J Intern Med] 2023 Feb; Vol. 108, pp. 117-119. Date of Electronic Publication: 2022 Sep 24.
Typ publikacji:
Letter
MeSH Terms:
Electronic Health Records*
Piperidines*/adverse effects
Humans ; United States/epidemiology ; Adenine ; Heart
Opinia redakcyjna
Szczegóły
Wyświetlanie 1-20 z 19825

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