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Tytuł :
Anti-staphylococcal effects of Myracrodruon urundeuva lectins on nonresistant and multidrug resistant isolates.
Autorzy :
Moura MC; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Procópio TF; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Ferreira GRS; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Alves RRV; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Sá RA; Centro Acadêmico do Agreste, Universidade Federal de Pernambuco, Caruaru, Pernambuco, Brazil.
Paiva PMG; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Ingmer H; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Coelho LCBB; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Napoleão TH; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
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Źródło :
Journal of applied microbiology [J Appl Microbiol] 2021 Mar; Vol. 130 (3), pp. 745-754. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Journal Article
MeSH Terms :
Anacardiaceae/*chemistry
Anti-Bacterial Agents/*pharmacology
Plant Lectins/*pharmacology
Staphylococcus aureus/*drug effects
Agglutination Tests ; Anti-Bacterial Agents/isolation & purification ; Biofilms/drug effects ; Drug Resistance, Multiple, Bacterial ; Drug Synergism ; Hemolysis/drug effects ; Humans ; Plant Lectins/isolation & purification ; Staphylococcus aureus/isolation & purification ; Staphylococcus aureus/pathogenicity ; Virulence/drug effects
Czasopismo naukowe
Tytuł :
Identification of monocot chimeric jacalin family reveals functional diversity in wheat.
Autorzy :
Ma QH; Key Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, 20 Nanxincun, Xiangshan, Beijing, 100093, China. .
Han JQ; Key Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, 20 Nanxincun, Xiangshan, Beijing, 100093, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
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Źródło :
Planta [Planta] 2021 Jan 09; Vol. 253 (2), pp. 30. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Genome, Plant*/genetics
Plant Lectins*/chemistry
Plant Lectins*/classification
Plant Lectins*/genetics
Plant Lectins*/metabolism
Plant Proteins*/genetics
Triticum*/genetics
Disease Resistance/genetics ; Tobacco/genetics
Czasopismo naukowe
Tytuł :
Soybean lectin induces autophagy through P2RX7 dependent activation of NF-κB-ROS pathway to kill intracellular mycobacteria.
Autorzy :
Mishra A; Laboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela 769008, Odisha, India.
Behura A; Laboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela 769008, Odisha, India.
Kumar A; Laboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela 769008, Odisha, India.
Ghosh A; Divison of Bioinformatics, Bose Institute, Kolkata 700054, West Bengal, India.
Naik L; Laboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela 769008, Odisha, India.
Mawatwal S; Laboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela 769008, Odisha, India.
Mohanty SS; Laboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela 769008, Odisha, India.
Mishra A; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342011, India.
Saha S; Divison of Bioinformatics, Bose Institute, Kolkata 700054, West Bengal, India.
Bhutia SK; Department of Life Science, National Institute of Technology, Rourkela 769008, Odisha, India.
Singh R; Tuberculosis Research Laboratory, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurugram Expressway, PO Box # 4, Faridabad 121001, Haryana, India.
Dhiman R; Laboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela 769008, Odisha, India. Electronic address: .
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2021 Feb; Vol. 1865 (2), pp. 129806. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Mycobacterium/*drug effects
NF-kappa B/*metabolism
Plant Lectins/*pharmacology
Signal Transduction/*drug effects
Soybean Proteins/*pharmacology
Anti-Bacterial Agents/isolation & purification ; Antitubercular Agents/isolation & purification ; Antitubercular Agents/pharmacology ; Autophagy/drug effects ; Cell Line ; Humans ; Macrophages/microbiology ; Models, Molecular ; Mycobacterium/physiology ; Mycobacterium Infections/drug therapy ; Mycobacterium Infections/metabolism ; Mycobacterium Infections/microbiology ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/physiology ; Plant Lectins/isolation & purification ; Reactive Oxygen Species/metabolism ; Soybean Proteins/isolation & purification ; Soybeans/chemistry ; Tuberculosis/drug therapy ; Tuberculosis/metabolism ; Tuberculosis/microbiology
Czasopismo naukowe
Tytuł :
Effects of Maackia amurensis seed lectin (MASL) on oral squamous cell carcinoma (OSCC) gene expression and transcriptional signaling pathways.
Autorzy :
Hamilton KL; Department of Molecular Biology, Science Center, Graduate School of Biomedical Sciences, School of Osteopathic Medicine, Rowan University, Stratford, NJ, 08084, USA.
Sheehan SA; Department of Molecular Biology, Science Center, Graduate School of Biomedical Sciences, School of Osteopathic Medicine, Rowan University, Stratford, NJ, 08084, USA.
Retzbach EP; Department of Molecular Biology, Science Center, Graduate School of Biomedical Sciences, School of Osteopathic Medicine, Rowan University, Stratford, NJ, 08084, USA.
Timmerman CA; Department of Molecular Biology, Science Center, Graduate School of Biomedical Sciences, School of Osteopathic Medicine, Rowan University, Stratford, NJ, 08084, USA.
Gianneschi GB; Department of Molecular Biology, Science Center, Graduate School of Biomedical Sciences, School of Osteopathic Medicine, Rowan University, Stratford, NJ, 08084, USA.
Tempera PJ; Department of Molecular Biology, Science Center, Graduate School of Biomedical Sciences, School of Osteopathic Medicine, Rowan University, Stratford, NJ, 08084, USA.
Balachandran P; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, MS, 38677, USA.
Goldberg GS; Department of Molecular Biology, Science Center, Graduate School of Biomedical Sciences, School of Osteopathic Medicine, Rowan University, Stratford, NJ, 08084, USA. .
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Feb; Vol. 147 (2), pp. 445-457. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic/*drug effects
Maackia/*chemistry
Mouth Neoplasms/*drug therapy
Plant Lectins/*pharmacology
Squamous Cell Carcinoma of Head and Neck/*drug therapy
Cell Movement/drug effects ; Humans ; Mouth Neoplasms/metabolism ; Mouth Neoplasms/pathology ; Plant Lectins/therapeutic use ; SOXB1 Transcription Factors/genetics ; Signal Transduction/drug effects ; Smad Proteins/genetics ; Squamous Cell Carcinoma of Head and Neck/metabolism ; Squamous Cell Carcinoma of Head and Neck/pathology ; Transcription, Genetic/drug effects ; Wnt Signaling Pathway/drug effects
Czasopismo naukowe
Tytuł :
A new lectin from the floral capitula of Egletes viscosa (EgviL): Biochemical and biophysical characterization and cytotoxicity to human cancer cells.
Autorzy :
Gomes DC; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Barros MR; Laboratório de Química Biológica, Departamento de Química Fundamental, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Menezes TM; Laboratório de Química Biológica, Departamento de Química Fundamental, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Neves JL; Laboratório de Química Biológica, Departamento de Química Fundamental, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Paiva PMG; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
da Silva TG; Departamento de Antibióticos, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Napoleão TH; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil. Electronic address: .
Coriolano MC; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil. Electronic address: .
Dos Santos Correia MT; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jan 31; Vol. 168, pp. 676-685. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Asteraceae/*chemistry
Leukocytes, Mononuclear/*cytology
Plant Lectins/*pharmacology
Antineoplastic Agents, Phytogenic/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Chemical Precipitation ; Drug Stability ; Galactose/metabolism ; Glucose/metabolism ; Hemagglutination Tests ; Humans ; Hydrophobic and Hydrophilic Interactions ; Inhibitory Concentration 50 ; Isoelectric Point ; Jurkat Cells ; Leukocytes, Mononuclear/drug effects ; MCF-7 Cells ; Plant Lectins/chemistry
Czasopismo naukowe
Tytuł :
Protein Sensing Device with Multi-Recognition Ability Composed of Self-Organized Glycopeptide Bundle.
Autorzy :
Arai M; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Show-ku, Nagoya 4668-555, Japan.
Miura T; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Show-ku, Nagoya 4668-555, Japan.
Ito Y; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Show-ku, Nagoya 4668-555, Japan.
Kinoshita T; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Show-ku, Nagoya 4668-555, Japan.
Higuchi M; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Show-ku, Nagoya 4668-555, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 31; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Electrodes*
Concanavalin A/*chemistry
Glycopeptides/*chemistry
Lipid Bilayers/*chemistry
Peanut Agglutinin/*chemistry
Plant Lectins/*chemistry
Binding Sites ; Concanavalin A/metabolism ; Glycopeptides/metabolism ; Gold ; Ion Channels ; Lipid Bilayers/metabolism ; Peanut Agglutinin/metabolism ; Plant Lectins/metabolism
Czasopismo naukowe
Tytuł :
Purification, biochemical/biophysical characterization and chitooligosaccharide binding to BGL24, a new PP2-type phloem exudate lectin from bottle gourd (Lagenaria siceraria).
Autorzy :
Mondal S; School of Chemistry, University of Hyderabad, Hyderabad 500046, India.
Swamy MJ; School of Chemistry, University of Hyderabad, Hyderabad 500046, India. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 01; Vol. 164, pp. 3656-3666. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article
MeSH Terms :
Chitin/*analogs & derivatives
Cucurbitaceae/*chemistry
Lectins/*chemistry
Plant Lectins/*chemistry
Amino Acid Sequence/genetics ; Biophysical Phenomena ; Chitin/chemistry ; Chitin/isolation & purification ; Chitin/pharmacology ; Exudates and Transudates/chemistry ; Exudates and Transudates/drug effects ; Lectins/ultrastructure ; Oligosaccharides/chemistry ; Plant Lectins/antagonists & inhibitors ; Protein Structure, Secondary
Czasopismo naukowe
Tytuł :
Comprehensive review on Caelsalpinioideae lectins: From purification to biological activities.
Autorzy :
Cavada BS; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Brazil. Electronic address: .
Pinto-Junior VR; Departamento de Física, Universidade Federal do Ceará, Fortaleza, Brazil.
Osterne VJS; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Brazil; Departamento de Nutrição, Universidade Estadual do Ceará, Fortaleza, Brazil.
Oliveira MV; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Brazil.
Lossio CF; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Brazil.
Silva MTL; Departamento de Bioquímica, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Bari AU; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Brazil.
Lima LD; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Brazil.
Souza-Filho CHD; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Brazil.
Nascimento KS; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Brazil.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Nov 01; Vol. 162, pp. 333-348. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antifungal Agents/*pharmacology
Antineoplastic Agents/*pharmacology
Antiviral Agents/*pharmacology
Bauhinia/*chemistry
Plant Lectins/*chemistry
Plant Lectins/*pharmacology
Amino Acid Sequence ; Anti-Inflammatory Agents/pharmacology ; Fabaceae/chemistry ; Metals/chemistry ; Molecular Conformation ; Phylogeny ; Plant Lectins/isolation & purification ; Plant Lectins/metabolism ; Protein Domains
Czasopismo naukowe
Tytuł :
In vitro effects of Moringa oleifera seed lectins on Haemonchus contortus in larval and adult stages.
Autorzy :
Medeiros MLS; Departamento de Ciências Biomédicas, Faculdade de Ciências da Saúde, Universidade do Estado do Rio Grande do Norte, Rua Atirador Miguel Antônio da Silva Neto, S/n, Aeroporto, 59607-360, Mossoró, Rio Grande do Norte, Brazil. Electronic address: .
Alves RRV; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Av. Professor Morais Rego S/n, Cidade Universitária, 50670-901, Recife, Pernambuco, Brazil.
Oliveira BF; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Av. Professor Morais Rego S/n, Cidade Universitária, 50670-901, Recife, Pernambuco, Brazil.
Napoleão TH; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Av. Professor Morais Rego S/n, Cidade Universitária, 50670-901, Recife, Pernambuco, Brazil.
Paiva PMG; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Av. Professor Morais Rego S/n, Cidade Universitária, 50670-901, Recife, Pernambuco, Brazil.
Coelho LCBB; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Av. Professor Morais Rego S/n, Cidade Universitária, 50670-901, Recife, Pernambuco, Brazil.
Bezerra ACDS; Departamento de Biociências, Centro de Ciências Biológicas e da Saúde, Universidade Federal Rural do Semi-Árido, Av. Francisco Mota 572, Costa e Silva, 59625-900, Mossoró, Rio Grande do Norte, Brazil.
Silva MDC; Departamento de Biociências, Centro de Ciências Biológicas e da Saúde, Universidade Federal Rural do Semi-Árido, Av. Francisco Mota 572, Costa e Silva, 59625-900, Mossoró, Rio Grande do Norte, Brazil. Electronic address: .
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Źródło :
Experimental parasitology [Exp Parasitol] 2020 Nov; Vol. 218, pp. 108004. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article
MeSH Terms :
Haemonchus/*drug effects
Moringa oleifera/*chemistry
Plant Lectins/*pharmacology
Seeds/*chemistry
Animals ; Female ; Haemonchus/enzymology ; Haemonchus/physiology ; Haemonchus/ultrastructure ; Larva/drug effects ; Male ; Microscopy, Electron, Scanning ; Movement/drug effects ; Peptide Hydrolases/metabolism ; Plant Lectins/administration & dosage ; Plant Lectins/isolation & purification
Czasopismo naukowe
Tytuł :
Investigation of the ability of the oviposition-stimulant lectin from Moringa oleifera seeds (WSMoL) to bind with membrane proteins present in the legs of Aedes aegypti.
Autorzy :
Silva LLS; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Brazil.
Santos NDL; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Brazil.
Silva SCC; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Brazil.
Lima TA; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Brazil.
Coelho LCBB; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Brazil.
Zingali RB; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Navarro DMDAF; Departamento de Química Fundamental, Centro de Ciências Exatas e da Natureza, Universidade Federal de Pernambuco, Recife, Brazil.
Napoleão TH; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Brazil.
Paiva PMG; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Brazil. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Nov 01; Vol. 162, pp. 657-662. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article
MeSH Terms :
Aedes*/anatomy & histology
Aedes*/chemistry
Plant Lectins*/chemistry
Plant Lectins*/pharmacology
Insect Proteins/*chemistry
Membrane Proteins/*chemistry
Moringa oleifera/*chemistry
Oviposition/*drug effects
Animals ; Insect Proteins/metabolism ; Membrane Proteins/metabolism
Czasopismo naukowe
Tytuł :
A novel mannose-binding lectin from Liparis nervosa with anti-fungal and anti-tumor activities.
Autorzy :
Jiang N; School of Life Sciences and Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, China.
Wang Y; School of Life Sciences and Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, China.
Zhou J; School of Life Sciences and Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, China.
Zheng R; School of Life Sciences and Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, China.
Yuan X; School of Life Sciences and Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, China.
Wu M; School of Life Sciences and Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, China.
Bao J; School of Life Sciences and Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, China.
Wu C; School of Life Sciences and Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610065, China.
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Źródło :
Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2020 Oct 19; Vol. 52 (10), pp. 1081-1092.
Typ publikacji :
Journal Article
MeSH Terms :
Antifungal Agents/*pharmacology
Antineoplastic Agents/*pharmacology
Mannose-Binding Lectins/*pharmacology
Orchidaceae/*chemistry
Plant Lectins/*pharmacology
Amino Acid Sequence ; Animals ; Antifungal Agents/chemistry ; Antifungal Agents/isolation & purification ; Antifungal Agents/metabolism ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Antineoplastic Agents/metabolism ; Apoptosis/drug effects ; Basidiomycota/drug effects ; Bipolaris/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Chromatography, Affinity ; Chromatography, Gel ; Chromatography, Ion Exchange ; Fusarium/drug effects ; Hemagglutination/drug effects ; Humans ; Mannose/metabolism ; Mannose-Binding Lectins/chemistry ; Mannose-Binding Lectins/isolation & purification ; Mannose-Binding Lectins/metabolism ; Molecular Docking Simulation ; Molecular Weight ; Orchidaceae/metabolism ; Plant Lectins/chemistry ; Plant Lectins/isolation & purification ; Plant Lectins/metabolism ; Rabbits ; Sequence Homology, Amino Acid
SCR Organism :
Athelia rolfsii; Bipolaris maydis; Fusarium graminearum
Czasopismo naukowe
Tytuł :
Efficacy of silk fibroin biomaterial vehicle for in vivo mucosal delivery of Griffithsin and protection against HIV and SHIV infection ex vivo.
Autorzy :
Crakes KR; Department of Medical Microbiology & Immunology, School of Medicine, University of California Davis, Davis, CA, USA.
Herrera C; Department of Medicine, St. Mary's Campus Imperial College, London, United Kingdom.
Morgan JL; Department of Molecular Cell Biology, University of California Merced, Merced, CA, USA.
Olstad K; California National Primate Research Center, University of California Davis, Davis, CA, USA.
Hessell AJ; Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Sciences University, Beaverton, OR, USA.
Ziprin P; Department of Surgery and Cancer, St. Mary's Campus Imperial College, London, United Kingdom.
LiWang PJ; Department of Molecular Cell Biology, University of California Merced, Merced, CA, USA.
Dandekar S; Department of Medical Microbiology & Immunology, School of Medicine, University of California Davis, Davis, CA, USA.
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Źródło :
Journal of the International AIDS Society [J Int AIDS Soc] 2020 Oct; Vol. 23 (10), pp. e25628.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Fibroins*
Anti-HIV Agents/*administration & dosage
HIV Infections/*prevention & control
Lectins/*administration & dosage
Plant Lectins/*administration & dosage
Simian Acquired Immunodeficiency Syndrome/*prevention & control
Animals ; Anti-HIV Agents/analysis ; Anti-HIV Agents/pharmacokinetics ; Biocompatible Materials ; Cervix Uteri/virology ; Colon/virology ; Female ; Gastrointestinal Microbiome/drug effects ; HIV/drug effects ; Humans ; Lectins/analysis ; Lectins/pharmacokinetics ; Macaca mulatta ; Microbiota/drug effects ; Mucous Membrane/chemistry ; Pharmaceutical Vehicles ; Plant Lectins/analysis ; Plant Lectins/pharmacokinetics ; Rectum/chemistry ; Rectum/microbiology ; Rectum/virology ; Vagina/chemistry ; Vagina/microbiology
Czasopismo naukowe
Tytuł :
Antinociceptive activity of Schinus terebinthifolia leaf lectin (SteLL) in sarcoma 180-bearing mice.
Autorzy :
Ramos DBM; Campus Amilcar Ferreira Sobral, Universidade Federal do Piauí, Floriano, Piauí, Brazil; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Araújo MTMF; Laboratório de Oncologia Experimental, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brazil.
Araújo TCL; Laboratório de Oncologia Experimental, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brazil.
Silva YA; Laboratório de Oncologia Experimental, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brazil.
Dos Santos ACLA; Laboratório de Oncologia Experimental, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brazil.
E Silva MG; Laboratório de Oncologia Experimental, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brazil.
Paiva PMG; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Mendes RL; Laboratório de Oncologia Experimental, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brazil.
Napoleão TH; Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2020 Sep 15; Vol. 259, pp. 112952. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Anacardiaceae*/chemistry
Plant Leaves*/chemistry
Analgesics/*pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Cancer Pain/*prevention & control
Hyperalgesia/*prevention & control
Nociceptive Pain/*prevention & control
Plant Lectins/*pharmacology
Sarcoma 180/*drug therapy
Analgesics/isolation & purification ; Animals ; Antineoplastic Agents, Phytogenic/isolation & purification ; Cancer Pain/etiology ; Cancer Pain/metabolism ; Cancer Pain/physiopathology ; Female ; Hyperalgesia/etiology ; Hyperalgesia/metabolism ; Hyperalgesia/physiopathology ; Mice ; Nociception/drug effects ; Nociceptive Pain/etiology ; Nociceptive Pain/metabolism ; Nociceptive Pain/physiopathology ; Pain Threshold/drug effects ; Plant Lectins/isolation & purification ; Reaction Time/drug effects ; Receptors, Opioid/metabolism ; Sarcoma 180/complications ; Sarcoma 180/pathology ; Signal Transduction ; Time Factors
Czasopismo naukowe
Tytuł :
A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2.
Autorzy :
Liu YM; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan; Institute of Microbiology and Immunology, National Yang Ming University, Taipei 112, Taiwan.
Shahed-Al-Mahmud M; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan.
Chen X; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan.
Chen TH; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan.
Liao KS; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan.
Lo JM; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan.
Wu YM; Institute of Biological Chemistry and Cryo-EM Center, Academia Sinica, Taipei 115, Taiwan.
Ho MC; Institute of Biological Chemistry and Cryo-EM Center, Academia Sinica, Taipei 115, Taiwan.
Wu CY; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan.
Wong CH; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan.
Jan JT; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan.
Ma C; Genomics Research Center, Academia Sinica, Taipei 115, Taiwan. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2020 Aug 11; Vol. 32 (6), pp. 108016. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*therapeutic use
Coronavirus Infections/*drug therapy
Fabaceae/*chemistry
Orthomyxoviridae Infections/*drug therapy
Plant Lectins/*therapeutic use
Pneumonia, Viral/*drug therapy
A549 Cells ; Administration, Intranasal ; Animals ; Antiviral Agents/administration & dosage ; Antiviral Agents/pharmacology ; Betacoronavirus/drug effects ; COVID-19 ; Chick Embryo ; Chlorocebus aethiops ; Dogs ; Female ; Humans ; Influenza A Virus, H1N1 Subtype/drug effects ; Madin Darby Canine Kidney Cells ; Mice ; Mice, Inbred BALB C ; Pandemics ; Plant Lectins/administration & dosage ; Plant Lectins/pharmacology ; Protein Binding ; SARS-CoV-2 ; Vero Cells ; Viral Envelope Proteins/metabolism
Czasopismo naukowe
Tytuł :
The barley lectin, horcolin, binds high-mannose glycans in a multivalent fashion, enabling high-affinity, specific inhibition of cellular HIV infection.
Autorzy :
Jayaprakash NG; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Singh A; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Vivek R; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Yadav S; Department of Organic Chemistry, Indian Institute of Science, Bangalore, India.
Pathak S; Department of Biochemistry, Indian Institute of Science, Bangalore, India.
Trivedi J; National Centre for Cell Science, Pune University, Pune, India.
Jayaraman N; Department of Organic Chemistry, Indian Institute of Science, Bangalore, India.
Nandi D; Department of Biochemistry, Indian Institute of Science, Bangalore, India.
Mitra D; National Centre for Cell Science, Pune University, Pune, India.
Surolia A; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Aug 21; Vol. 295 (34), pp. 12111-12129. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
HIV Infections*
HIV Envelope Protein gp120/*chemistry
HIV-1/*chemistry
Hordeum/*chemistry
Mannose/*chemistry
Plant Lectins/*chemistry
Polysaccharides/*chemistry
env Gene Products, Human Immunodeficiency Virus/*chemistry
Animals ; HEK293 Cells ; HIV-1/metabolism ; Hordeum/genetics ; Humans ; Male ; Mice ; Plant Lectins/genetics ; Rabbits
Czasopismo naukowe
Tytuł :
Heterologous production of α-chain of Dioclea sclerocarpa lectin: Enhancing the biological effects of a wild-type lectin.
Autorzy :
Nascimento KS; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, 60440970 Fortaleza, Ceará, Brazil.
Andrade MLL; Universidade Federal do Rio Grande do Norte, Escola Agrícola de Jundiaí, Distrito de Jundiaí, 59280000 Macaíba, Rio Grande do Norte, Brazil.
Silva IB; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, 60440970 Fortaleza, Ceará, Brazil.
Domingues DL; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, 60440970 Fortaleza, Ceará, Brazil.
Chicas LS; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, 60440970 Fortaleza, Ceará, Brazil.
Silva MTL; Departamento de Bioquímica e Programa de Pós-graduação em Bioquímica, Universidade Federal de Santa Catarina, Campus Universitário, 88040900 Florianópolis, Santa Catarina, Brazil.
Bringel PHSF; Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Campus do Itaperi, 60714903 Fortaleza, Ceará, Brazil.
Marques GFO; Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Campus do Itaperi, 60714903 Fortaleza, Ceará, Brazil.
Martins MGQ; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, 60440970 Fortaleza, Ceará, Brazil; Centro Universitário INTA, Programa de pós-graduação em Biotecnologia, Sobral, Ceará, Brazil.
Lóssio CF; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, 60440970 Fortaleza, Ceará, Brazil.
Nascimento APM; Departamento de Bioquímica e Programa de Pós-graduação em Bioquímica, Universidade Federal de Santa Catarina, Campus Universitário, 88040900 Florianópolis, Santa Catarina, Brazil.
Wolin IAV; Departamento de Bioquímica e Programa de Pós-graduação em Bioquímica, Universidade Federal de Santa Catarina, Campus Universitário, 88040900 Florianópolis, Santa Catarina, Brazil.
Leal RB; Departamento de Bioquímica e Programa de Pós-graduação em Bioquímica, Universidade Federal de Santa Catarina, Campus Universitário, 88040900 Florianópolis, Santa Catarina, Brazil.
Assreuy AMS; Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Campus do Itaperi, 60714903 Fortaleza, Ceará, Brazil. Electronic address: .
Cavada BS; Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Campus do Pici, 60440970 Fortaleza, Ceará, Brazil. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Aug 01; Vol. 156, pp. 1-9. Date of Electronic Publication: 2020 Apr 07.
Typ publikacji :
Journal Article
MeSH Terms :
Dioclea/*chemistry
Plant Lectins/*chemistry
Animals ; Aorta/drug effects ; Cell Line, Tumor ; Chromatography, Affinity ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Glioma/metabolism ; Hemagglutination ; Mannose/chemistry ; Plant Lectins/metabolism ; Protein Structure, Secondary ; Rats ; Recombinant Proteins/analysis ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/pharmacology ; Seeds/chemistry ; Vasodilator Agents/chemistry
Czasopismo naukowe
Tytuł :
Abrus agglutinin inhibits oral carcinogenesis through inactivation of NRF2 signaling pathway.
Autorzy :
Panigrahi DP; Cancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India.
Bhol CS; Cancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India.
R N; Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, Tamil Nadu, India.
Nagini S; Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, Tamil Nadu, India.
Patil S; Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Saudi Arabia.
Maiti TK; Department of Biotechnology, Indian Institute of Technology, Kharagpur, India.
Bhutia SK; Cancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Jul 15; Vol. 155, pp. 1123-1132. Date of Electronic Publication: 2019 Nov 09.
Typ publikacji :
Journal Article
MeSH Terms :
Autophagy*
9,10-Dimethyl-1,2-benzanthracene/*toxicity
Abrus/*chemistry
Mouth Neoplasms/*drug therapy
NF-E2-Related Factor 2/*antagonists & inhibitors
Plant Lectins/*pharmacology
Animals ; Apoptosis ; Carcinogens/toxicity ; Cell Line, Tumor ; Cell Proliferation ; Cricetinae ; Humans ; Male ; Mouth Neoplasms/chemically induced ; Mouth Neoplasms/metabolism ; Mouth Neoplasms/pathology ; NF-E2-Related Factor 2/metabolism ; Plant Lectins/chemistry ; Reactive Oxygen Species/chemistry ; Signal Transduction
Czasopismo naukowe
Tytuł :
Evaluation of the Cardiac Effects of a Water-Soluble Lectin (Wsmol) from Moringa Oleifera Seeds.
Autorzy :
Yurre AR; Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Silva JDFD; Universidade Federal de Pernambuco, Recife, PE, Brasil.
Torres MKDS; Universidade Federal de Pernambuco, Recife, PE, Brasil.
Martins EL; Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Ramos IP; Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Silva WSFLD; Universidade Federal de Pernambuco, Recife, PE, Brasil.
Sarpa JDS; Universidade Federal de Pernambuco, Recife, PE, Brasil.
Guedes CCDS; Universidade Federal de Pernambuco, Recife, PE, Brasil.
Napoleão TH; Universidade Federal de Pernambuco, Recife, PE, Brasil.
Coelho LCBB; Universidade Federal de Pernambuco, Recife, PE, Brasil.
Paiva PMG; Universidade Federal de Pernambuco, Recife, PE, Brasil.
Medei E; Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
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Transliterated Title :
Avaliação dos Efeitos Cardíacos de Lectina Solúvel em Água (WSMoL) de Sementes de Moringa Oleifera.
Źródło :
Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2020 Jun; Vol. 114 (6), pp. 1029-1037. Date of Electronic Publication: 2020 Mar 13.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Moringa oleifera/*chemistry
Plant Extracts/*pharmacology
Plant Lectins/*pharmacology
Seeds/*chemistry
Animals ; Mice ; Plant Extracts/chemistry ; Plant Lectins/isolation & purification ; Water
Czasopismo naukowe
Tytuł :
A lectin with anti-microbial and anti proliferative activities from Lantana camara, a medicinal plant.
Autorzy :
Hiremath KY; Department of Studies in Biochemistry, Karnatak University, Dharwad, 580003, India.
Jagadeesh N; Department of Studies in Biochemistry, Karnatak University, Dharwad, 580003, India.
Belur S; Department of Studies in Biochemistry, Karnatak University, Dharwad, 580003, India.
Kulkarni SS; Department of Studies in Biochemistry, Karnatak University, Dharwad, 580003, India.
Inamdar SR; Department of Studies in Biochemistry, Karnatak University, Dharwad, 580003, India. Electronic address: .
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Źródło :
Protein expression and purification [Protein Expr Purif] 2020 Jun; Vol. 170, pp. 105574. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antifungal Agents/*pharmacology
Antineoplastic Agents/*pharmacology
Lantana/*chemistry
Plant Lectins/*pharmacology
Anti-Bacterial Agents/isolation & purification ; Antifungal Agents/isolation & purification ; Antineoplastic Agents/isolation & purification ; Chitin/chemistry ; Chitin/metabolism ; Chromatography, Affinity ; Chromatography, Gel ; Chromatography, Ion Exchange ; Electrophoresis, Polyacrylamide Gel ; Fungi/drug effects ; Fungi/growth & development ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/growth & development ; HT29 Cells ; Humans ; Melibiose/chemistry ; Melibiose/metabolism ; Methylgalactosides/chemistry ; Methylgalactosides/metabolism ; Microbial Sensitivity Tests ; Mucins/chemistry ; Mucins/metabolism ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; Plant Lectins/isolation & purification ; Plants, Medicinal ; Protein Binding
Czasopismo naukowe

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