- Tytuł:
-
Phase I and pharmacokinetic study of irinotecan in combination with R115777,
a farnesyl protein transferase inhibitor. - Autorzy:
- Źródło:
- British journal of cancer [Br J Cancer] 2004 Apr 19; Vol. 90 (8), pp. 1508-15.
- Typ publikacji:
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Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.
S . Gov't - MeSH Terms:
-
Antineoplastic Combined Chemotherapy Protocols /*adverse effectsAntineoplastic Combined Chemotherapy Protocols /*pharmacokinetics
Camptothecin/*analogs & derivatives
Neoplasms/*drug therapy
Administration, Oral ; Adult ; Aged ;Antineoplastic Combined Chemotherapy Protocols /therapeutic use ; Camptothecin/administration & dosage ; Camptothecin/adverse effects ; Camptothecin/pharmacokinetics ; Female ; Humans ; Infusions, Intravenous ; Irinotecan ; Male ; Maximum Tolerated Dose ; Middle Aged ; Quinolones/administration & dosage ; Quinolones/adverse effects ; Quinolones/pharmacokinetics ; Treatment Outcome
Czasopismo naukowe