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Wyszukujesz frazę ""Platelet Activation"" wg kryterium: Temat


Tytuł:
Impact of Levosimendan and Its Metabolites on Platelet Activation Mechanisms in Patients during Antiplatelet Therapy-Pilot Study.
Autorzy:
Sikora J; Research and Education Unit for Experimental Biotechnology, Department of Transplantology and General Surgery, Collegium Medicum, Nicolaus Copernicus University, 85-094 Bydgoszcz, Poland.
Pstrągowski K; Department of Cardiology and Internal Medicine, Antoni Jurasz University Hospital No. 1 in Bydgoszcz, 85-094 Bydgoszcz, Poland.
Karczmarska-Wódzka A; Research and Education Unit for Experimental Biotechnology, Department of Transplantology and General Surgery, Collegium Medicum, Nicolaus Copernicus University, 85-094 Bydgoszcz, Poland.
Wszelaki P; Research and Education Unit for Experimental Biotechnology, Department of Transplantology and General Surgery, Collegium Medicum, Nicolaus Copernicus University, 85-094 Bydgoszcz, Poland.
Buszko K; Department of Theoretical Foundations of Biomedical Science and Medical Informatics, Collegium Medicum, Nicolaus Copernicus University, 85-094 Bydgoszcz, Poland.
Włodarczyk Z; Department of Transplantology and General Surgery, Collegium Medicum, Nicolaus Copernicus University, 85-094 Bydgoszcz, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 02; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Platelet Aggregation Inhibitors*/pharmacology
Platelet Aggregation Inhibitors*/therapeutic use
Platelet Aggregation*
Humans ; Simendan/pharmacology ; Simendan/therapeutic use ; Pilot Projects ; Platelet Activation ; Blood Platelets
Czasopismo naukowe
Tytuł:
Coumarin Derivatives Inhibit ADP-Induced Platelet Activation and Aggregation.
Autorzy:
Lu PH; Department of Chinese Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231, Taiwan.; School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien 970, Taiwan.
Liao TH; Department of Chinese Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231, Taiwan.
Chen YH; Department of Chemistry, Tamkang University, New Taipei City 251, Taiwan.
Hsu YL; Department of Applied Chemistry, National Chia-Yi University, Chiayi City 600, Taiwan.
Kuo CY; Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231, Taiwan.
Chan CC; Department of Laboratory Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231, Taiwan.
Wang LK; Department of Life Sciences, Ministry of Science and Technology, Taipei 106, Taiwan.
Chern CY; Department of Applied Chemistry, National Chia-Yi University, Chiayi City 600, Taiwan.
Tsai FM; Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231, Taiwan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jun 23; Vol. 27 (13). Date of Electronic Publication: 2022 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
Platelet Activation*
Platelet Aggregation*
Adenosine Diphosphate/pharmacology ; Blood Platelets ; Coumarins/pharmacology ; Platelet Aggregation Inhibitors/pharmacology ; Platelet Glycoprotein GPIIb-IIIa Complex/pharmacology
Czasopismo naukowe
Tytuł:
Impact of electric cardioversion on platelet activation.
Autorzy:
Haidl H; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Gaugler J; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Cvirn G; Division of Physiological Chemistry, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Jasser-Nitsche H; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Schwinger W; Division of Paediatric Haematology/Oncology, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Pohl S; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Bisping E; Division of Cardiology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Gallistl S; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Schlagenhauf A; Division of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
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Źródło:
PloS one [PLoS One] 2021 Apr 22; Vol. 16 (4), pp. e0250353. Date of Electronic Publication: 2021 Apr 22 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Platelet Activation*/drug effects
Platelet Aggregation*/drug effects
Atrial Fibrillation/*therapy
Electric Countershock/*adverse effects
Adenosine Diphosphate/pharmacology ; Adult ; Aged ; Arachidonic Acid/pharmacology ; Atrial Fibrillation/blood ; Blood Coagulation/drug effects ; Collagen/pharmacology ; Female ; Humans ; Male ; Middle Aged ; Peptide Fragments/pharmacology ; Platelet Factor 4/blood ; Platelet Function Tests/methods ; Ristocetin/pharmacology ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Pannexin-1 Activation by Phosphorylation Is Crucial for Platelet Aggregation and Thrombus Formation.
Autorzy:
Metz LM; Department of Vascular and Endovascular Surgery, Experimental Vascular Medicine, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Elvers M; Department of Vascular and Endovascular Surgery, Experimental Vascular Medicine, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 02; Vol. 23 (9). Date of Electronic Publication: 2022 May 02.
Typ publikacji:
Journal Article
MeSH Terms:
Connexins*/metabolism
Platelet Aggregation*/physiology
Thrombosis*/metabolism
Adenosine Triphosphate/metabolism ; Animals ; Blood Platelets/metabolism ; Humans ; Mice ; Nerve Tissue Proteins/metabolism ; Phosphorylation ; Platelet Activation
Czasopismo naukowe
Tytuł:
Platelet activation and aggregation in different centrifugal-flow left ventricular assist devices.
Autorzy:
Tscharre M; Department of Internal Medicine, Cardiology and Nephrology, Landesklinikum Wiener Neustadt, Wiener Neustadt, Austria.; Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
Wittmann F; Department of Surgery, Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Kitzmantl D; Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
Lee S; Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
Eichelberger B; Department of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Vienna, Austria.
Wadowski PP; Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
Laufer G; Department of Surgery, Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Wiedemann D; Department of Surgery, Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Forstner-Bergauer B; Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Ay C; Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.; I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Panzer S; Department of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Vienna, Austria.
Zimpfer D; Department of Surgery, Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Gremmel T; Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.; Department of Internal Medicine I, Cardiology and Intensive Care Medicine, Landesklinikum Mistelbach-Gänserndorf, Mistelbach, Austria.
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Źródło:
Platelets [Platelets] 2022 Feb 17; Vol. 33 (2), pp. 249-256. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji:
Journal Article
MeSH Terms:
Heart-Assist Devices/*standards
Platelet Activation/*physiology
Platelet Aggregation/*physiology
Aged ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies
Czasopismo naukowe
Tytuł:
Regulation of Key Antiplatelet Pathways by Bioactive Compounds with Minimal Bleeding Risk.
Autorzy:
Fuentes E; Thrombosis Research Center, Medical Technology School, Faculty of Health Sciences, Universidad de Talca, Talca 3460000, Chile.
Wehinger S; Department of Clinical Biochemistry and Immunohematology, Faculty of Health Sciences, Universidad de Talca, Talca 3460000, Chile.
Trostchansky A; Departamento de Bioquímica and Center for Free Radical and Biomedical Research, Facultad de Medicina, Universidad de la República, Montevideo 11800, Uruguay.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 17; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Blood Platelets/*metabolism
Hemorrhage/*prevention & control
Phytochemicals/*therapeutic use
Platelet Activation/*drug effects
Platelet Aggregation/*drug effects
Platelet Aggregation Inhibitors/*therapeutic use
Thrombosis/*drug therapy
Animals ; Blood Platelets/drug effects ; Hemorrhage/metabolism ; Hemostasis/drug effects ; Humans ; Phytochemicals/pharmacology ; Plaque, Atherosclerotic/metabolism ; Platelet Aggregation Inhibitors/pharmacology ; Thrombosis/metabolism
Czasopismo naukowe
Tytuł:
1,8-Cineole Affects Agonists-Induced Platelet Activation, Thrombus Formation and Haemostasis.
Autorzy:
Alatawi KA; School of Pharmacy, University of Reading, Reading RG6 6UB, UK.
Ravishankar D; School of Pharmacy, University of Reading, Reading RG6 6UB, UK.
Patra PH; School of Pharmacy, University of Reading, Reading RG6 6UB, UK.
Bye AP; School of Biological Sciences, University of Reading, Reading RG6 6UB, UK.
Stainer AR; School of Biological Sciences, University of Reading, Reading RG6 6UB, UK.
Patel K; School of Biological Sciences, University of Reading, Reading RG6 6UB, UK.
Widera D; School of Pharmacy, University of Reading, Reading RG6 6UB, UK.
Vaiyapuri S; School of Pharmacy, University of Reading, Reading RG6 6UB, UK.
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Źródło:
Cells [Cells] 2021 Oct 01; Vol. 10 (10). Date of Electronic Publication: 2021 Oct 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets/*drug effects
Eucalyptol/*pharmacology
Hemostasis/*drug effects
Platelet Activation/*drug effects
Platelet Aggregation/*drug effects
Animals ; Cells, Cultured ; Humans ; Mice ; Thrombosis/drug therapy
Czasopismo naukowe
Tytuł:
Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis.
Autorzy:
Flora GD; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.; Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.
Sahli KA; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.; General Directorate of Medical Services, Ministry of Interior, Riyadh, Kingdom of Saudi Arabia.
Sasikumar P; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.; Centre for Haematology, Imperial College London, London, UK.
Holbrook LM; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.; School of Cardiovascular Medicine and Sciences, King's College London, London, UK.
Stainer AR; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.
AlOuda SK; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.
Crescente M; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.; Centre for Immunobiology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Sage T; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.
Unsworth AJ; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.; School of Healthcare Science, Manchester Metropolitan University, Manchester, UK.
Gibbins JM; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK. .
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Źródło:
Scientific reports [Sci Rep] 2019 Nov 20; Vol. 9 (1), pp. 17210. Date of Electronic Publication: 2019 Nov 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hemostasis*
Platelet Activation*
Platelet Aggregation*
Blood Platelets/*physiology
Pregnane X Receptor/*metabolism
Thrombosis/*pathology
Animals ; Humans ; Ligands ; Mice ; Receptors, Steroid/metabolism ; Thrombosis/metabolism ; src-Family Kinases/metabolism
Czasopismo naukowe
Tytuł:
Opposing Roles of GSK3α and GSK3β Phosphorylation in Platelet Function and Thrombosis.
Autorzy:
Moore SF; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Agbani EO; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.
Wersäll A; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Poole AW; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Williams CM; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Zhao X; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Li Y; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Hutchinson JL; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Hunter RW; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.; NHS Blood and Transplant, North Bristol Park, Filton, Bristol BS34 7QH, UK.
Hers I; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 30; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelets/*metabolism
Glycogen Synthase Kinase 3/*metabolism
Glycogen Synthase Kinase 3 beta/*metabolism
Platelet Activation/*genetics
Platelet Aggregation/*genetics
Signal Transduction/*genetics
Thrombosis/*metabolism
Animals ; Blood Donors ; Cells, Cultured ; Disease Models, Animal ; Gene Knock-In Techniques ; Glycogen Synthase Kinase 3/genetics ; Glycogen Synthase Kinase 3 beta/genetics ; Humans ; Integrins/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Thrombin/metabolism ; Thrombosis/genetics
Czasopismo naukowe
Tytuł:
Effect of advanced glycation end products on platelet activation and aggregation: a comparative study of the role of glyoxal and methylglyoxal.
Autorzy:
Arriagada-Petersen C; Escuela De Nutrición Y Dietética, Facultad De Ciencias De La Salud, Universidad De Talca, Talca, Chile.
Fernandez P; Escuela De Nutrición Y Dietética, Facultad De Ciencias De La Salud, Universidad De Talca, Talca, Chile.
Gomez M; Escuela De Nutrición Y Dietética, Facultad De Ciencias De La Salud, Universidad De Talca, Talca, Chile.
Ravello N; Escuela De Nutrición Y Dietética, Facultad De Ciencias De La Salud, Universidad De Talca, Talca, Chile.
Palomo I; Thrombosis Research Center, Medical Technology School, Department of Clinical Biochemistry and Immunohaematology, Faculty of Health Sciences, Universidad De Talca, Talca, Chile.
Fuentes E; Thrombosis Research Center, Medical Technology School, Department of Clinical Biochemistry and Immunohaematology, Faculty of Health Sciences, Universidad De Talca, Talca, Chile.
Ávila F; Escuela De Nutrición Y Dietética, Facultad De Ciencias De La Salud, Universidad De Talca, Talca, Chile.
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Źródło:
Platelets [Platelets] 2021 May 19; Vol. 32 (4), pp. 507-515. Date of Electronic Publication: 2020 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Glycation End Products, Advanced/*adverse effects
Glyoxal/*therapeutic use
Platelet Activation/*genetics
Platelet Aggregation/*genetics
Pyruvaldehyde/*therapeutic use
Glyoxal/pharmacology ; Humans ; Pyruvaldehyde/pharmacology
Czasopismo naukowe
Tytuł:
Anti-Inflammatory and Anti-Platelet Properties of Lipid Bioactives from Apple Cider By-Products.
Autorzy:
Tsoupras A; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.; Health Research Institute, University of Limerick, V94 T9PX Limerick, Ireland.; Bernal Institute, University of Limerick, V94 T9PX Limerick, Ireland.
Moran D; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Byrne T; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Ryan J; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Barrett L; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Traas C; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Zabetakis I; Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.; Health Research Institute, University of Limerick, V94 T9PX Limerick, Ireland.; Bernal Institute, University of Limerick, V94 T9PX Limerick, Ireland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 May 12; Vol. 26 (10). Date of Electronic Publication: 2021 May 12.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Fruit/*chemistry
Fruit and Vegetable Juices/*analysis
Linoleic Acid/*pharmacology
Malus/*chemistry
Phytochemicals/*pharmacology
Platelet Activation/*drug effects
Platelet Aggregation/*drug effects
alpha-Linolenic Acid/*pharmacology
Blood Donors ; Chromatography, High Pressure Liquid ; Functional Food/analysis ; Gas Chromatography-Mass Spectrometry ; Humans ; Phosphatidylcholines/pharmacology
Czasopismo naukowe
Tytuł:
Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity.
Autorzy:
Oggero S; William Harvey Research Institute Bart's and the London School of Medicine Queen Mary University of London London UK.
de Gaetano M; Diabetes Complications Research Centre Conway Institute, & School of Medicine University College Dublin Dublin Ireland.
Marcone S; Trinity Translational Medicine Institute Trinity College Dublin Dublin Ireland.
Fitzsimons S; Diabetes Complications Research Centre Conway Institute, & School of Medicine University College Dublin Dublin Ireland.
Pinto AL; Royal Brompton & Harefield NHS Foundation Trust London UK.
Ikramova D; School of Engineering and Materials Science Queen Mary University of London London UK.
Barry M; Department of Vascular Surgery St. Vincent's University Hospital Dublin Ireland.
Burke D; Department of Vascular Surgery St. Vincent's University Hospital Dublin Ireland.
Montero-Melendez T; William Harvey Research Institute Bart's and the London School of Medicine Queen Mary University of London London UK.; Centre for inflammation and Therapeutic Innovation Queen Mary University of London London UK.
Cooper D; William Harvey Research Institute Bart's and the London School of Medicine Queen Mary University of London London UK.; Centre for inflammation and Therapeutic Innovation Queen Mary University of London London UK.
Burgoyne T; Royal Brompton & Harefield NHS Foundation Trust London UK.; Institute of Ophthalmology, Faculty of Brain Sciences University College London London UK.
Belton O; Diabetes Complications Research Centre Conway Institute, & School of Medicine University College Dublin Dublin Ireland.
Norling LV; William Harvey Research Institute Bart's and the London School of Medicine Queen Mary University of London London UK.; Centre for inflammation and Therapeutic Innovation Queen Mary University of London London UK.
Brennan EP; Diabetes Complications Research Centre Conway Institute, & School of Medicine University College Dublin Dublin Ireland.
Godson C; Diabetes Complications Research Centre Conway Institute, & School of Medicine University College Dublin Dublin Ireland.
Perretti M; William Harvey Research Institute Bart's and the London School of Medicine Queen Mary University of London London UK.; Centre for inflammation and Therapeutic Innovation Queen Mary University of London London UK.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2021 Apr; Vol. 10 (6), pp. 12084. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Extracellular Vesicles/*physiology
Monocytes/*physiology
Plaque, Atherosclerotic/*physiopathology
Platelet Aggregation/*physiology
Aspirin/pharmacology ; Atherosclerosis/physiopathology ; Blood Platelets/cytology ; Blood Platelets/drug effects ; Cytokines ; Endothelial Cells/drug effects ; Extracellular Vesicles/drug effects ; Extracellular Vesicles/metabolism ; Healthy Volunteers ; Humans ; Inflammation/immunology ; Monocytes/cytology ; Platelet Activation/drug effects ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł:
Exogenous Integrin αIIbβ3 Inhibitors Revisited: Past, Present and Future Applications.
Autorzy:
van den Kerkhof DL; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
van der Meijden PEJ; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
Hackeng TM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
Dijkgraaf I; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 25; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Platelet Activation/*drug effects
Platelet Aggregation/*drug effects
Platelet Aggregation Inhibitors/*pharmacology
Platelet Glycoprotein GPIIb-IIIa Complex/*metabolism
Thrombosis/*therapy
Actins/chemistry ; Ancylostoma ; Animals ; Binding Sites ; Blood Platelets/metabolism ; Diptera ; Disintegrins/chemistry ; Drug Design ; Fibrinolytic Agents/pharmacology ; Humans ; Ligands ; Platelet Function Tests ; Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors ; Signal Transduction ; Snake Venoms/metabolism ; Snakes
Czasopismo naukowe
Tytuł:
Platelet function in disseminated intravascular coagulation: A systematic review.
Autorzy:
Laursen MA; a Centre for Haemophilia and Thrombosis, Department of Clinical Biochemistry , Aarhus University Hospital , Aarhus N , Denmark.
Larsen JB; a Centre for Haemophilia and Thrombosis, Department of Clinical Biochemistry , Aarhus University Hospital , Aarhus N , Denmark.
Hvas AM; a Centre for Haemophilia and Thrombosis, Department of Clinical Biochemistry , Aarhus University Hospital , Aarhus N , Denmark.; b Department of Clinical Medicine , Aarhus University , Aarhus , Denmark.
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Źródło:
Platelets [Platelets] 2018 May; Vol. 29 (3), pp. 238-248. Date of Electronic Publication: 2018 Mar 08.
Typ publikacji:
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms:
Blood Coagulation*
Platelet Activation*
Platelet Aggregation*
Blood Platelets/*metabolism
Disseminated Intravascular Coagulation/*blood
Disseminated Intravascular Coagulation/*diagnosis
Animals ; Biomarkers ; Disease Models, Animal ; Disseminated Intravascular Coagulation/epidemiology ; Disseminated Intravascular Coagulation/etiology ; Humans ; Platelet Function Tests ; Population Surveillance
Czasopismo naukowe
Tytuł:
Plasmin-Induced Activation of Human Platelets Is Modulated by Thrombospondin-1, Bona Fide Misfolded Proteins and Thiol Isomerases.
Autorzy:
Pielsticker C; Department of Anaesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Haemostasis, University of Muenster, 48149 Muenster, Germany.
Brodde MF; OxProtect GmbH, 48149 Muenster, Germany.
Raum L; Department of Anaesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Haemostasis, University of Muenster, 48149 Muenster, Germany.
Jurk K; Department of Anaesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Haemostasis, University of Muenster, 48149 Muenster, Germany.; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Kehrel BE; Department of Anaesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Haemostasis, University of Muenster, 48149 Muenster, Germany.; OxProtect GmbH, 48149 Muenster, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 23; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelets/*metabolism
Inflammation/*genetics
Platelet Aggregation/*genetics
Thrombospondin 1/*blood
Fibrinogen/genetics ; Fibrinogen/metabolism ; Fibrinolysin/metabolism ; Humans ; Inflammation/blood ; Inflammation/metabolism ; Isomerases/genetics ; Isomerases/metabolism ; P-Selectin/blood ; P-Selectin/genetics ; Peptides/genetics ; Peptides/pharmacology ; Plasminogen/genetics ; Plasminogen/metabolism ; Platelet Activation/genetics ; Protein Aggregates/genetics ; Protein Conformation, beta-Strand ; Protein Folding/drug effects ; Sulfhydryl Compounds/blood ; Sulfhydryl Compounds/metabolism ; Thrombospondin 1/genetics
Czasopismo naukowe
Tytuł:
Platelet activation and aggregation by the opportunistic pathogen Cutibacterium (Propionibacterium) acnes.
Autorzy:
Petersson F; Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Kilsgård O; Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.; Department of Immunotechnology, Faculty of Engineering Lund, Lund University, Lund, Sweden.
Shannon O; Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Lood R; Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
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Źródło:
PloS one [PLoS One] 2018 Jan 31; Vol. 13 (1), pp. e0192051. Date of Electronic Publication: 2018 Jan 31 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Platelet Activation*
Platelet Aggregation*
Propionibacterium acnes/*physiology
Blood Proteins/metabolism ; Humans ; Mass Spectrometry ; Microscopy, Fluorescence
Czasopismo naukowe
Tytuł:
Application of an optimized flow cytometry-based quantification of Platelet Activation (PACT): Monitoring platelet activation in platelet concentrates.
Autorzy:
Kicken CH; Department of Anesthesiology and Pain Therapy, Maastricht University Medical Center, Maastricht, the Netherlands.; Synapse Research Institute, Maastricht, the Netherlands.
Roest M; Synapse Research Institute, Maastricht, the Netherlands.; Department of Biochemistry, Cardiovascular Research Institute, Maastricht University, Maastricht, the Netherlands.
Henskens YM; Central Diagnostic Laboratory, Maastricht University Medical Center, Maastricht, the Netherlands.
de Laat B; Synapse Research Institute, Maastricht, the Netherlands.; Department of Biochemistry, Cardiovascular Research Institute, Maastricht University, Maastricht, the Netherlands.
Huskens D; Synapse Research Institute, Maastricht, the Netherlands.; Department of Biochemistry, Cardiovascular Research Institute, Maastricht University, Maastricht, the Netherlands.
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Źródło:
PloS one [PLoS One] 2017 Feb 16; Vol. 12 (2), pp. e0172265. Date of Electronic Publication: 2017 Feb 16 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Platelet Activation*
Platelet Aggregation*
Blood Platelets/*metabolism
Flow Cytometry/*methods
Flow Cytometry/*standards
Platelet Function Tests/*instrumentation
Platelet Function Tests/*methods
Blood Preservation ; Humans
Czasopismo naukowe
Tytuł:
Alteration of platelet GPVI signaling in ST-elevation myocardial infarction patients demonstrated by a combination of proteomic, biochemical, and functional approaches.
Autorzy:
Vélez P; Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Ocaranza-Sánchez R; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; Cardiology Department and Coronary Care Unit, Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain.
López-Otero D; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; Cardiology Department and Coronary Care Unit, Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain.
Grigorian-Shamagian L; Heart Institute, Cedars-Sinai Medical Center, Los Angeles, USA.
Rosa I; Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Guitián E; Mass Spectrometry and Proteomic Unit, Rede de Infraestructuras de Apoio á Investigación e ao Desenvolvemento Tecnolóxico (RIAIDT), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
García-Acuña JM; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; Cardiology Department and Coronary Care Unit, Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain.
González-Juanatey JR; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; Cardiology Department and Coronary Care Unit, Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain.
García Á; Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
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Źródło:
Scientific reports [Sci Rep] 2016 Dec 22; Vol. 6, pp. 39603. Date of Electronic Publication: 2016 Dec 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Platelet Activation*
Platelet Aggregation*
Signal Transduction*
Blood Platelets/*metabolism
Platelet Membrane Glycoproteins/*metabolism
ST Elevation Myocardial Infarction/*metabolism
Aged ; Cohort Studies ; Collagen/chemistry ; Coronary Artery Disease/metabolism ; Female ; Humans ; Male ; Middle Aged ; Phosphorylation ; Proteomics ; Thrombosis/metabolism
Czasopismo naukowe
Tytuł:
Microfluidics for simultaneous quantification of platelet adhesion and blood viscosity.
Autorzy:
Yeom E; School of Mechanical Engineering, Pusan National University, Busan, South Korea.
Park JH; Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, South Korea.
Kang YJ; Department of Mechanical Engineering, Chosun University, Gwangju, South Korea.
Lee SJ; Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, South Korea.
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Źródło:
Scientific reports [Sci Rep] 2016 Apr 27; Vol. 6, pp. 24994. Date of Electronic Publication: 2016 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Viscosity*
Platelet Activation*
Platelet Aggregation*
Blood Platelets/*physiology
Microfluidics/*methods
Animals ; Microfluidics/instrumentation ; Rats
Czasopismo naukowe
Tytuł:
Pharmacological inhibition of S6K1 facilitates platelet activation by enhancing Akt phosphorylation.
Autorzy:
Gao W; a Department of Cardiology , Huashan Hospital, Fudan University , Shanghai , China.
Wang K; b Department of Biochemistry and Molecular Cell Biology , Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Zhang L; b Department of Biochemistry and Molecular Cell Biology , Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Li J; a Department of Cardiology , Huashan Hospital, Fudan University , Shanghai , China.
Liu J; b Department of Biochemistry and Molecular Cell Biology , Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Chen X; b Department of Biochemistry and Molecular Cell Biology , Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Luo X; a Department of Cardiology , Huashan Hospital, Fudan University , Shanghai , China.
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Źródło:
Platelets [Platelets] 2019; Vol. 30 (2), pp. 241-250. Date of Electronic Publication: 2017 Dec 19.
Typ publikacji:
Journal Article
MeSH Terms:
Platelet Activation/*genetics
Platelet Aggregation/*genetics
Proto-Oncogene Proteins c-akt/*genetics
Ribosomal Protein S6 Kinases, 70-kDa/*antagonists & inhibitors
Ribosomal Protein S6 Kinases, 70-kDa/*therapeutic use
Animals ; Humans ; Mice ; Phosphorylation ; Ribosomal Protein S6 Kinases, 70-kDa/pharmacology ; Signal Transduction
Czasopismo naukowe

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