Temat: "Point Mutation" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Predicting protein stability changes upon single-point mutation: a thorough comparison of the available tools on a new dataset.
Autorzy:: Pancotti C; Department of Medical Sciences, University of Torino, Via Santena 19, 10126 Torino, Italy.
Benevenuta S; Department of Medical Sciences, University of Torino, Via Santena 19, 10126 Torino, Italy.
Birolo G; Department of Medical Sciences, University of Torino, Via Santena 19, 10126 Torino, Italy.
Alberini V; Department of Medical Sciences, University of Torino, Via Santena 19, 10126 Torino, Italy.
Repetto V; Department of Medical Sciences, University of Torino, Via Santena 19, 10126 Torino, Italy.
Sanavia T; Department of Medical Sciences, University of Torino, Via Santena 19, 10126 Torino, Italy.
Capriotti E; Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Bologna, Italy.
Fariselli P; Department of Medical Sciences, University of Torino, Via Santena 19, 10126 Torino, Italy.; Pokaż więcej
Źródło:: Briefings in bioinformatics [Brief Bioinform] 2022 Mar 10; Vol. 23 (2).
Typ publikacji:: Journal Article
MeSH Terms:: Point Mutation*
Proteins*/chemistry
Mutation ; Protein Stability ; Thermodynamics

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Skocz do pozycji: 2.

Tytuł:: A novel oncostatin M/interleukin-31 receptor mutation in familial primary localized cutaneous amyloidosis.
Autorzy:: Adams R; European Cancer Stem Cell Research Institute, Cardiff School of Biosciences, Cardiff University, Cardiff, UK.
Colmont C; Molecular and Experimental Medicine, Department of Nephrology, Cardiff University School of Medicine, Cardiff, UK.
Mukhtar A; European Cancer Stem Cell Research Institute, Cardiff School of Biosciences, Cardiff University, Cardiff, UK.
Morgan H; European Cancer Stem Cell Research Institute, Cardiff School of Biosciences, Cardiff University, Cardiff, UK.
Patel GK; European Cancer Stem Cell Research Institute, Cardiff School of Biosciences, Cardiff University, Cardiff, UK.; Pokaż więcej
Źródło:: Clinical and experimental dermatology [Clin Exp Dermatol] 2020 Mar; Vol. 45 (2), pp. 254-256. Date of Electronic Publication: 2019 Sep 03.
Typ publikacji:: Case Reports; Journal Article; Review
MeSH Terms:: Point Mutation*
Amyloidosis, Familial/*genetics
Oncostatin M/*genetics
Receptors, Interleukin/*genetics
Skin Diseases, Genetic/*genetics
Adult ; Amyloidosis, Familial/pathology ; Heterozygote ; Humans ; Male ; Skin/pathology ; Skin Diseases, Genetic/pathology
SCR Disease Name:: Amyloidosis, Primary Cutaneous

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Skocz do pozycji: 3.

Tytuł:: A DISC1 point mutation promotes oligomerization and impairs information processing in a mouse model of schizophrenia.
Autorzy:: Kakuda K; United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, 1-1 Yanagido, Gifu.
Niwa A; Department of Tumor Pathology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu.
Honda R; United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, 1-1 Yanagido, Gifu.
Yamaguchi KI; Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka.
Tomita H; Department of Tumor Pathology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu.
Nojebuzzaman M; Division of Regeneration Technology, Gifu University Graduate School of Medicine, Gifu, Japan.
Hara A; Department of Tumor Pathology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu.
Goto Y; Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka.
Osawa M; Division of Regeneration Technology, Gifu University Graduate School of Medicine, Gifu, Japan.
Kuwata K; United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, 1-1 Yanagido, Gifu.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2019 Apr 01; Vol. 165 (4), pp. 369-378.
Typ publikacji:: Journal Article
MeSH Terms:: Nerve Tissue Proteins*/genetics
Nerve Tissue Proteins*/metabolism
Point Mutation*
Protein Multimerization*
Schizophrenia*/genetics
Schizophrenia*/metabolism
Schizophrenia*/pathology
Schizophrenia*/physiopathology
Amino Acid Substitution ; Animals ; Disease Models, Animal ; Humans ; Mice ; Mice, Mutant Strains

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Skocz do pozycji: 4.

Tytuł:: A Single Residue Mutation in the Gα q Subunit of the G Protein Complex Causes Blindness in Drosophila .
Autorzy:: Cao J; Department of Medicine, Jinggang Shan University, Ji'an 343009, China.
Bollepalli MK; Department of Physiology, Development and Neuroscience, University of Cambridge, CB2 3DY, United Kingdom.
Hu Y; Department of Medicine, Jinggang Shan University, Ji'an 343009, China.
Zhang J; School of Basic Medical Sciences, Nanchang University, Jiangxi 330031, China.
Li Q; School of Life Sciences, Institute of Entomology, State Key Laboratory of Biocontrol, Sun Yat-sen University, Guangzhou 510006, China.
Li H; School of Life Sciences, Institute of Entomology, State Key Laboratory of Biocontrol, Sun Yat-sen University, Guangzhou 510006, China.
Chang H; School of Life Sciences, Institute of Entomology, State Key Laboratory of Biocontrol, Sun Yat-sen University, Guangzhou 510006, China.
Xiao F; Department of Medicine, Jinggang Shan University, Ji'an 343009, China.
Hardie RC; Department of Physiology, Development and Neuroscience, University of Cambridge, CB2 3DY, United Kingdom.
Rong YS; School of Life Sciences, Institute of Entomology, State Key Laboratory of Biocontrol, Sun Yat-sen University, Guangzhou 510006, China .
Hu W; School of Life Sciences, Institute of Entomology, State Key Laboratory of Biocontrol, Sun Yat-sen University, Guangzhou 510006, China .; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2018 Jan 04; Vol. 8 (1), pp. 363-371. Date of Electronic Publication: 2018 Jan 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Point Mutation*
Vision, Ocular*
Drosophila Proteins/*deficiency
Drosophila melanogaster/*genetics
GTP-Binding Protein alpha Subunits, Gq-G11/*deficiency
Retinal Degeneration/*genetics
Alleles ; Animals ; Drosophila Proteins/genetics ; Drosophila melanogaster/metabolism ; Electroretinography ; GTP-Binding Protein alpha Subunits, Gq-G11/genetics ; Gene Expression Regulation ; Light ; Protein Binding ; Retina/metabolism ; Retina/pathology ; Retinal Degeneration/metabolism ; Retinal Degeneration/pathology ; Type C Phospholipases/genetics ; Type C Phospholipases/metabolism

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Skocz do pozycji: 5.

Tytuł:: Large-Scale Low-Cost NGS Library Preparation Using a Robust Tn5 Purification and Tagmentation Protocol.
Autorzy:: Hennig BP; Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany.
Velten L; Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany.
Racke I; Protein Expression and Purification Core Facility, European Molecular Biology Laboratory, Heidelberg 69117, Germany.
Tu CS; Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany.
Thoms M; Biochemistry Center Heidelberg, Heidelberg University, 69120, Germany.
Rybin V; Protein Expression and Purification Core Facility, European Molecular Biology Laboratory, Heidelberg 69117, Germany.
Besir H; Protein Expression and Purification Core Facility, European Molecular Biology Laboratory, Heidelberg 69117, Germany.
Remans K; Protein Expression and Purification Core Facility, European Molecular Biology Laboratory, Heidelberg 69117, Germany .
Steinmetz LM; Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany .; Department of Genetics, Stanford University School of Medicine, California 94305.; Stanford Genome Technology Center, Stanford University School of Medicine, Palo Alto, California 94304.; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2018 Jan 04; Vol. 8 (1), pp. 79-89. Date of Electronic Publication: 2018 Jan 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Library*
Point Mutation*
High-Throughput Nucleotide Sequencing/*methods
Recombinant Fusion Proteins/*genetics
Transposases/*genetics
Base Sequence ; Cloning, Molecular/methods ; DNA/genetics ; DNA/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; HeLa Cells ; High-Throughput Nucleotide Sequencing/economics ; Humans ; Polyadenylation ; Protein Binding ; Recombinant Fusion Proteins/metabolism ; Transposases/metabolism

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Skocz do pozycji: 6.

Tytuł:: A novel aceE mutation leading to a better growth profile and a higher L-serine production in a high-yield L-serine-producing Corynebacterium glutamicum strain.
Autorzy:: Guo W; Laboratory of Pharmaceutical Engineering, School of Pharmaceutics Science, Jiangnan University, Wuxi, 214122, People's Republic of China.; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, People's Republic of China.
Chen Z; Laboratory of Pharmaceutical Engineering, School of Pharmaceutics Science, Jiangnan University, Wuxi, 214122, People's Republic of China.; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, People's Republic of China.
Zhang X; Laboratory of Pharmaceutical Engineering, School of Pharmaceutics Science, Jiangnan University, Wuxi, 214122, People's Republic of China.; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, People's Republic of China.
Xu G; Laboratory of Pharmaceutical Engineering, School of Pharmaceutics Science, Jiangnan University, Wuxi, 214122, People's Republic of China.; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.
Zhang X; Laboratory of Pharmaceutical Engineering, School of Pharmaceutics Science, Jiangnan University, Wuxi, 214122, People's Republic of China.
Shi J; Laboratory of Pharmaceutical Engineering, School of Pharmaceutics Science, Jiangnan University, Wuxi, 214122, People's Republic of China.; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, People's Republic of China.
Xu Z; Laboratory of Pharmaceutical Engineering, School of Pharmaceutics Science, Jiangnan University, Wuxi, 214122, People's Republic of China. .; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, People's Republic of China. .; Pokaż więcej
Źródło:: Journal of industrial microbiology & biotechnology [J Ind Microbiol Biotechnol] 2016 Sep; Vol. 43 (9), pp. 1293-301. Date of Electronic Publication: 2016 Jun 25.
Typ publikacji:: Journal Article
MeSH Terms:: Point Mutation*
Corynebacterium glutamicum/*genetics
Pyruvate Dehydrogenase Complex/*genetics
Serine/*metabolism
Corynebacterium glutamicum/enzymology ; Corynebacterium glutamicum/growth & development ; Corynebacterium glutamicum/metabolism ; Genetic Variation ; Genomics ; Metabolic Engineering ; Mutagenesis

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Skocz do pozycji: 7.

Tytuł:: Sdt97: A Point Mutation in the 5' Untranslated Region Confers Semidwarfism in Rice.
Autorzy:: Tong J; Department of Rice Breeding, Tianjin Crop Institute, Tianjin P.R., 300384 China .
Han Z; Department of Rice Breeding, Tianjin Crop Institute, Tianjin P.R., 300384 China.
Han A; Department of Rice Breeding, Tianjin Crop Institute, Tianjin P.R., 300384 China.
Liu X; Department of Rice Breeding, Tianjin Crop Institute, Tianjin P.R., 300384 China .
Zhang S; Department of Rice Breeding, Shangdong Rice Institute, Shandong Province, P.R. 250100 China.
Fu B; Department of Crop Molecular Biology, Institute of Crop Sciences of CAAS, Beijing P.R., 10081 China.
Hu J; Key Laboratory of MOE for Plant Developmental Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei Province P.R., 430072 China.
Su J; Department of Rice Breeding, Tianjin Crop Institute, Tianjin P.R., 300384 China.
Li S; Key Laboratory of MOE for Plant Developmental Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei Province P.R., 430072 China.
Wang S; Department of Rice Breeding, Tianjin Crop Institute, Tianjin P.R., 300384 China.
Zhu Y; Key Laboratory of MOE for Plant Developmental Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei Province P.R., 430072 China.; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2016 Jun 01; Vol. 6 (6), pp. 1491-502. Date of Electronic Publication: 2016 Jun 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: 5' Untranslated Regions*
Genes, Plant*
Point Mutation*
Quantitative Trait, Heritable*
Oryza/*genetics
Base Sequence ; Breeding ; Chromosome Mapping ; Cloning, Molecular ; DNA Mutational Analysis ; Gene Expression Regulation, Plant ; Genetic Association Studies ; Genotype ; Phenotype ; Plants, Genetically Modified ; Polymorphism, Single Nucleotide

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Skocz do pozycji: 8.

Tytuł:: RNA-recognition motifs and glycine and arginine-rich region cooperatively regulate the nucleolar localization of nucleolin.
Autorzy:: Okuwaki M; Laboratory of Biochemistry, School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.; Department of Infection Biology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
Saotome-Nakamura A; Department of Infection Biology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
Yoshimura M; Laboratory of Biochemistry, School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Saito S; Laboratory of Biochemistry, School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.; Department of Infection Biology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
Hirawake-Mogi H; Laboratory of Biochemistry, School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Sekiya T; Department of Infection Biology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
Nagata K; Department of Infection Biology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2021 Feb 06; Vol. 169 (1), pp. 87-100.
Typ publikacji:: Journal Article
MeSH Terms:: Arginine/*metabolism
Cell Nucleolus/*metabolism
Glycine/*metabolism
Nuclear Proteins/*metabolism
Phosphoproteins/*metabolism
RNA-Binding Motifs/*genetics
RNA-Binding Proteins/*metabolism
Amino Acid Sequence/genetics ; Arginine/genetics ; Glycine/genetics ; HeLa Cells ; Humans ; Nuclear Proteins/genetics ; Phosphoproteins/genetics ; Point Mutation ; Protein Transport ; RNA, Ribosomal/genetics ; RNA, Ribosomal/metabolism ; RNA-Binding Proteins/genetics ; Nucleolin

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Skocz do pozycji: 9.

Tytuł:: Escherichia coli with a Tunable Point Mutation Rate for Evolution Experiments.
Autorzy:: Sherer NA; Department of Physics and.; Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, IL 61801, and.
Kuhlman TE; Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, IL 61801, and .; Department of Physics and Astronomy, University of California Riverside, Riverside, CA 92521.; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2020 Aug 05; Vol. 10 (8), pp. 2671-2681. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Escherichia coli Proteins*/genetics
Mutation Rate*
Escherichia coli/genetics ; Mutation ; Point Mutation ; Selection, Genetic

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Skocz do pozycji: 10.

Tytuł:: Frequency and features of TP53 mutation in 30 Chinese patients with sporadic basal cell carcinoma.
Autorzy:: Wang YM; Department of Dermatology, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China.
Huang YS
Ma ZH
Bu DF
Wang Y
Tu P
Li H; Pokaż więcej
Źródło:: Clinical and experimental dermatology [Clin Exp Dermatol] 2014 Oct; Vol. 39 (7), pp. 829-34. Date of Electronic Publication: 2014 Sep 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genes, p53*
Point Mutation*/radiation effects
Carcinoma, Basal Cell/*genetics
Skin Neoplasms/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Asian People/genetics ; China ; Female ; Gene Frequency ; Genetic Predisposition to Disease ; Humans ; Male ; Middle Aged ; Patched Receptors ; Patched-1 Receptor ; Receptors, Cell Surface/genetics ; Ultraviolet Rays/adverse effects ; Young Adult

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Skocz do pozycji: 11.

Tytuł:: Comparison of gal-lac operons in wild-type galactose-positive and -negative Streptococcus thermophilus by genomics and transcription analysis.
Autorzy:: Xiong ZQ; Shanghai Engineering Research Center of Food Microbiology, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Kong LH; Shanghai Engineering Research Center of Food Microbiology, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Meng HL; Bioengineering Research Center, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou, 511458, China.
Cui JM; Bioengineering Research Center, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou, 511458, China.
Xia YJ; Shanghai Engineering Research Center of Food Microbiology, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Wang SJ; Shijiazhuang Junlebao Dairy Co. Ltd., Shijiazhuang, 050211, China.
Ai LZ; Shanghai Engineering Research Center of Food Microbiology, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China. .; Pokaż więcej
Źródło:: Journal of industrial microbiology & biotechnology [J Ind Microbiol Biotechnol] 2019 May; Vol. 46 (5), pp. 751-758. Date of Electronic Publication: 2019 Feb 04.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Bacterial*
Lac Operon*
Galactose/*chemistry
Streptococcus thermophilus/*genetics
Base Sequence ; Genome, Bacterial ; Genomics ; Glucose/metabolism ; Industrial Microbiology ; Lactose/metabolism ; Operon ; Phenotype ; Point Mutation ; Promoter Regions, Genetic ; Sequence Analysis, RNA ; Transcriptome

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Skocz do pozycji: 12.

Tytuł:: Multiple functions of the ER-resident VAP and its extracellular role in neural development and disease.
Autorzy:: Kamemura K; Department of Biological Science, Graduate School of Science, Hiroshima University, Hiroshima, Japan.
Chihara T; Department of Biological Science, Graduate School of Science, Hiroshima University, Hiroshima, Japan.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2019 May 01; Vol. 165 (5), pp. 391-400.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Endoplasmic Reticulum/*metabolism
Membrane Proteins/*metabolism
Amino Acid Sequence ; Amyotrophic Lateral Sclerosis/metabolism ; Animals ; Biological Transport ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/metabolism ; Cytosol/metabolism ; Humans ; Lipid Metabolism ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Membrane Proteins/physiology ; Microtubules/metabolism ; Point Mutation ; Sequence Homology, Amino Acid ; Unfolded Protein Response

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Skocz do pozycji: 13.

Tytuł:: Point mutation of the xylose reductase (XR) gene reduces xylitol accumulation and increases citric acid production in Aspergillus carbonarius.
Autorzy:: Weyda I; Section for Sustainable Biotechnology, Aalborg University Copenhagen, A. C. Meyers Vænge 15, 2450, Copenhagen SV, Denmark.
Lübeck M
Ahring BK
Lübeck PS; Pokaż więcej
Źródło:: Journal of industrial microbiology & biotechnology [J Ind Microbiol Biotechnol] 2014 Apr; Vol. 41 (4), pp. 733-9. Date of Electronic Publication: 2014 Feb 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Point Mutation*
Aldehyde Reductase/*genetics
Aspergillus/*enzymology
Citric Acid/*metabolism
Xylitol/*metabolism
Aldehyde Reductase/metabolism ; Aspergillus/genetics ; Aspergillus/metabolism ; Candida/enzymology ; D-Xylulose Reductase/metabolism ; Fermentation ; NAD/metabolism ; NADP/metabolism ; Xylose/metabolism

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Skocz do pozycji: 14.

Tytuł:: Short-Homology-Mediated CRISPR/Cas9-Based Method for Genome Editing in Fission Yeast.
Autorzy:: Hayashi A; Department of Bioscience, School of Science and Technology, Kwansei Gakuin University, Sanda, Hyogo, 669-1337, Japan .
Tanaka K; Department of Bioscience, School of Science and Technology, Kwansei Gakuin University, Sanda, Hyogo, 669-1337, Japan .; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2019 Apr 09; Vol. 9 (4), pp. 1153-1163. Date of Electronic Publication: 2019 Apr 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Editing/*methods
Schizosaccharomyces/*genetics
Schizosaccharomyces pombe Proteins/*genetics
CRISPR-Cas Systems ; Cloning, Molecular ; Genetic Vectors ; Mutagenesis, Site-Directed ; Point Mutation ; Schizosaccharomyces pombe Proteins/chemistry

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Skocz do pozycji: 15.

Tytuł:: Effect of an MCM4 mutation that causes tumours in mouse on human MCM4/6/7 complex formation.
Autorzy:: Watanabe E; College of Science, Ibaraki University, 2-1-1 Bunkyo, Mito, Ibaraki 351-8511, Japan.
Ohara R
Ishimi Y; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2012 Aug; Vol. 152 (2), pp. 191-8. Date of Electronic Publication: 2012 Jun 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Point Mutation*
Cell Cycle Proteins/*genetics
Cell Cycle Proteins/*metabolism
DNA-Binding Proteins/*genetics
DNA-Binding Proteins/*metabolism
Nuclear Proteins/*genetics
Nuclear Proteins/*metabolism
Animals ; Cell Nucleus/metabolism ; Cells, Cultured ; HeLa Cells ; Humans ; Mice ; Minichromosome Maintenance Complex Component 4 ; Minichromosome Maintenance Complex Component 6 ; Minichromosome Maintenance Complex Component 7 ; Multiprotein Complexes

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Skocz do pozycji: 16.

Tytuł:: Function of the amino-terminal region of human MCM4 in helicase activity.
Autorzy:: Wang X; College of Science, Ibaraki University, Mito, Ibaraki, Japan.
Ishimi Y; College of Science, Ibaraki University, Mito, Ibaraki, Japan.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2018 Dec 01; Vol. 164 (6), pp. 449-460.
Typ publikacji:: Journal Article
MeSH Terms:: Protein Processing, Post-Translational*
S Phase*
Cyclin A/*metabolism
Cyclin-Dependent Kinase 2/*metabolism
Minichromosome Maintenance Complex Component 4/*metabolism
Minichromosome Maintenance Complex Component 6/*metabolism
Minichromosome Maintenance Complex Component 7/*metabolism
Amino Acid Substitution ; Arginine/chemistry ; Enzyme Stability ; Gene Deletion ; HeLa Cells ; Humans ; Minichromosome Maintenance Complex Component 4/chemistry ; Minichromosome Maintenance Complex Component 4/genetics ; Minichromosome Maintenance Complex Component 6/chemistry ; Minichromosome Maintenance Complex Component 6/genetics ; Minichromosome Maintenance Complex Component 7/chemistry ; Minichromosome Maintenance Complex Component 7/genetics ; Mutagenesis, Site-Directed ; Oligopeptides/chemistry ; Oligopeptides/genetics ; Oligopeptides/metabolism ; Peptide Fragments/chemistry ; Peptide Fragments/genetics ; Peptide Fragments/metabolism ; Phosphorylation ; Point Mutation ; Protein Multimerization ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/metabolism

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Skocz do pozycji: 17.

Tytuł:: A Cloning-Free Method for CRISPR/Cas9-Mediated Genome Editing in Fission Yeast.
Autorzy:: Zhang XR; National Institute of Biological Sciences, Beijing, China 102206.
He JB; National Institute of Biological Sciences, Beijing, China 102206.; College of Biological Sciences, China Agricultural University, Beijing, China 100193.
Wang YZ; PTN Graduate Program, School of Life Sciences, Tsinghua University, Beijing, China 100084.
Du LL; National Institute of Biological Sciences, Beijing, China 102206 .; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2018 May 31; Vol. 8 (6), pp. 2067-2077. Date of Electronic Publication: 2018 May 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CRISPR-Cas Systems/*genetics
Gene Editing/*methods
Schizosaccharomyces/*genetics
Base Sequence ; Cloning, Molecular ; DNA Repair/genetics ; Gene Knock-In Techniques ; Point Mutation/genetics ; Sequence Deletion ; Temperature

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Skocz do pozycji: 18.

Tytuł:: A Flow Cytometry-Based Phenotypic Screen To Identify Novel Endocytic Factors in Saccharomyces cerevisiae .
Autorzy:: Wrasman K; Department of Biology, Johns Hopkins University Baltimore, MD 21218.
Alioto SL; Department of Biology, Brandeis University, Waltham, MA 02453.
Zhang Y; Department of Biology, Johns Hopkins University Baltimore, MD 21218.
Hoban K; Department of Biology, Johns Hopkins University Baltimore, MD 21218.
Khairy M; Department of Biology, Johns Hopkins University Baltimore, MD 21218.
Goode BL; Department of Biology, Brandeis University, Waltham, MA 02453.
Wendland B; Department of Biology, Johns Hopkins University Baltimore, MD 21218 .; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2018 May 04; Vol. 8 (5), pp. 1497-1512. Date of Electronic Publication: 2018 May 04.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Endocytosis*
Flow Cytometry/*methods
Saccharomyces cerevisiae/*cytology
Saccharomyces cerevisiae/*genetics
Amino Acid Sequence ; Cell Membrane/metabolism ; Green Fluorescent Proteins/metabolism ; Mutagenesis/genetics ; Mutation, Missense/genetics ; Phenotype ; Point Mutation/genetics ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism