A strategy for large-scale comparison of evolutionary- and reaction-based classifications of enzyme function.
Autorzy:
Holliday GL; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA.; Present Address: Medicines Discovery Catapult, Mereside, Alderley Park, Alderley Edge SK10 4TG, UK. Brown SD; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA. Mischel D; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA. PolaccoBJ; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA. Babbitt PC; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA.; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA.; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA.
Organic and inorganic mercurials have distinct effects on cellular thiols, metal homeostasis, and Fe-binding proteins in Escherichia coli.
Autorzy:
LaVoie SP; Department of Microbiology, University of Georgia, Athens, GA, 30602, USA. Mapolelo DT; Department of Chemistry, University of Georgia, Athens, GA, 30602, USA.; Department of Chemistry, University of Botswana, P.O. Box 00704, Gaborone, Botswana. Cowart DM; Department of Chemistry, University of Georgia, Athens, GA, 30602, USA. PolaccoBJ; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA. Johnson MK; Department of Chemistry, University of Georgia, Athens, GA, 30602, USA. Scott RA; Department of Chemistry, University of Georgia, Athens, GA, 30602, USA. Miller SM; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA. Summers AO; Department of Microbiology, University of Georgia, Athens, GA, 30602, USA. .
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