Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Poly\(A\)-Binding Proteins"" wg kryterium: Temat


Tytuł:
Identification of novel proteins and mRNAs differentially bound to the Leishmania Poly(A) Binding Proteins reveals a direct association between PABP1, the RNA-binding protein RBP23 and mRNAs encoding ribosomal proteins.
Autorzy:
Assis LA; Department of Microbiology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil.; Department of Genetics, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Santos Filho MVC; Department of Microbiology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil.; Department of Genetics, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
da Cruz Silva JR; Department of Microbiology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil.
Bezerra MJR; Department of Microbiology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil.
de Aquino IRPUC; Department of Microbiology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil.
Merlo KC; Department of Microbiology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil.
Holetz FB; Laboratory of Gene Expression Regulation, Carlos Chagas Institute, Oswaldo Cruz Foundation, Curitiba, Paraná, Brazil.
Probst CM; Laboratory of Gene Expression Regulation, Carlos Chagas Institute, Oswaldo Cruz Foundation, Curitiba, Paraná, Brazil.
Rezende AM; Department of Microbiology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil.
Papadopoulou B; CHU de Quebec Research Center and Department of Microbiology-Infectious Disease and Immunology, Laval University, Quebec, Quebec, Canada.
da Costa Lima TDC; University Center Tabosa de Almeida, Caruaru, Pernambuco, Brazil.
de Melo Neto OP; Department of Microbiology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Pernambuco, Brazil.
Pokaż więcej
Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Oct 27; Vol. 15 (10), pp. e0009899. Date of Electronic Publication: 2021 Oct 27 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Leishmania/*metabolism
Poly(A)-Binding Proteins/*metabolism
Protozoan Proteins/*metabolism
RNA, Messenger/*metabolism
RNA-Binding Proteins/*metabolism
Ribosomal Proteins/*metabolism
Leishmania/genetics ; Poly(A)-Binding Proteins/genetics ; Protein Binding ; Protein Biosynthesis ; Protozoan Proteins/genetics ; RNA, Messenger/genetics ; RNA-Binding Proteins/genetics ; Ribosomal Proteins/genetics
Czasopismo naukowe
Tytuł:
Translation Initiation Regulated by RNA-Binding Protein in Mammals: The Modulation of Translation Initiation Complex by Trans-Acting Factors.
Autorzy:
Fukao A; Department of Pharmacy, Kindai University, Kowakae 3-4-1, Higashi-Osaka City 577-8502, Japan.
Tomohiro T; Department of Pharmacy, Kindai University, Kowakae 3-4-1, Higashi-Osaka City 577-8502, Japan.
Fujiwara T; Department of Pharmacy, Kindai University, Kowakae 3-4-1, Higashi-Osaka City 577-8502, Japan.
Pokaż więcej
Źródło:
Cells [Cells] 2021 Jul 06; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Peptide Chain Initiation, Translational*
Argonaute Proteins/*genetics
Eukaryotic Initiation Factor-4F/*genetics
Poly(A)-Binding Proteins/*genetics
RNA Caps/*genetics
Transcription Factors/*genetics
Animals ; Argonaute Proteins/metabolism ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; ELAV-Like Protein 4/genetics ; ELAV-Like Protein 4/metabolism ; Eukaryotic Initiation Factor-4E/genetics ; Eukaryotic Initiation Factor-4E/metabolism ; Eukaryotic Initiation Factor-4F/metabolism ; Humans ; Mammals ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Poly A/genetics ; Poly A/metabolism ; Poly(A)-Binding Proteins/metabolism ; Protein Binding ; RNA Caps/chemistry ; RNA Caps/metabolism ; RNA Stability ; RNA-Induced Silencing Complex/genetics ; RNA-Induced Silencing Complex/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Pbp1, the yeast ortholog of human Ataxin-2, functions in the cell growth on non-fermentable carbon sources.
Autorzy:
Tuong Vi DT; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Fujii S; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Valderrama AL; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan.
Ito A; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Matsuura E; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Nishihata A; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Irie K; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Suda Y; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Live Cell Super-Resolution Imaging Research Team, RIKEN Center for Advanced Photonics, Wako, Saitama, Japan.
Mizuno T; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Irie K; Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.; Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2021 May 13; Vol. 16 (5), pp. e0251456. Date of Electronic Publication: 2021 May 13 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Poly(A)-Binding Proteins/*metabolism
Saccharomyces cerevisiae/*growth & development
Saccharomyces cerevisiae Proteins/*metabolism
Ataxin-2/metabolism ; Carbon/metabolism ; Fermentation ; Gene Deletion ; Gene Expression Regulation, Fungal ; Gluconeogenesis ; Humans ; Poly(A)-Binding Proteins/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł:
Gene variants of coagulation related proteins that interact with SARS-CoV-2.
Autorzy:
Holcomb D; Center for Biologics Evaluation and Research, Office of Tissues and Advanced Therapies, Division of Plasma Protein Therapeutics, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Alexaki A; Center for Biologics Evaluation and Research, Office of Tissues and Advanced Therapies, Division of Plasma Protein Therapeutics, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Hernandez N; Center for Biologics Evaluation and Research, Office of Tissues and Advanced Therapies, Division of Plasma Protein Therapeutics, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Hunt R; Center for Biologics Evaluation and Research, Office of Tissues and Advanced Therapies, Division of Plasma Protein Therapeutics, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Laurie K; Center for Biologics Evaluation and Research, Office of Tissues and Advanced Therapies, Division of Plasma Protein Therapeutics, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Kames J; Center for Biologics Evaluation and Research, Office of Tissues and Advanced Therapies, Division of Plasma Protein Therapeutics, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Hamasaki-Katagiri N; Center for Biologics Evaluation and Research, Office of Tissues and Advanced Therapies, Division of Plasma Protein Therapeutics, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Komar AA; Center for Gene Regulation in Health and Disease, Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, United States of America.
DiCuccio M; National Center of Biotechnology Information, National Institutes of Health, Bethesda, Maryland, United States of America.
Kimchi-Sarfaty C; Center for Biologics Evaluation and Research, Office of Tissues and Advanced Therapies, Division of Plasma Protein Therapeutics, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Pokaż więcej
Źródło:
PLoS computational biology [PLoS Comput Biol] 2021 Mar 17; Vol. 17 (3), pp. e1008805. Date of Electronic Publication: 2021 Mar 17 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Coagulation*
Blood Proteins/*genetics
COVID-19/*metabolism
Complement C1 Inhibitor Protein/*genetics
Poly(A)-Binding Proteins/*genetics
SARS-CoV-2/*metabolism
Vitamin K Epoxide Reductases/*genetics
Anticoagulants/administration & dosage ; Blood Proteins/metabolism ; COVID-19/physiopathology ; COVID-19/virology ; Complement C1 Inhibitor Protein/metabolism ; Genome-Wide Association Study ; Humans ; Models, Molecular ; Mutation ; Poly(A)-Binding Proteins/metabolism ; Protein Binding ; SARS-CoV-2/genetics ; Severity of Illness Index ; Viral Proteins/metabolism ; Vitamin K Epoxide Reductases/metabolism ; Warfarin/administration & dosage
Czasopismo naukowe
Tytuł:
Cytoplasmic poly(A)-binding protein 1 (PABPC1) is a prognostic biomarker to predict survival in nasopharyngeal carcinoma regardless of chemoradiotherapy.
Autorzy:
Ling F; Pathology Department of the First Affiliated Hospital, Southwest Medical University, Sichuan, People's Republic of China.
Xu S; Department of Otorhinolaryngology-Head and Neck Surgery, the Affiliated Hospital of Southwest Medical University, Sichuan, People's Republic of China.
Li X; Pathology Department of the First Affiliated Hospital, Southwest Medical University, Sichuan, People's Republic of China.
Sun X; Pathology Department of the First Affiliated Hospital, Southwest Medical University, Sichuan, People's Republic of China.
Long W; Pathology Department of the First Affiliated Hospital, Southwest Medical University, Sichuan, People's Republic of China. .
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2023 Feb 20; Vol. 23 (1), pp. 169. Date of Electronic Publication: 2023 Feb 20.
Typ publikacji:
Journal Article
MeSH Terms:
Nasopharyngeal Carcinoma*/diagnosis
Nasopharyngeal Carcinoma*/therapy
Nasopharyngeal Neoplasms*/diagnosis
Nasopharyngeal Neoplasms*/therapy
Poly(A)-Binding Protein I*/genetics
Humans ; Chemoradiotherapy ; Induction Chemotherapy ; Ki-67 Antigen ; Paclitaxel/therapeutic use ; Poly(A)-Binding Proteins ; Prognosis ; Tumor Suppressor Protein p53
Czasopismo naukowe
Tytuł:
Molecular Insights into mRNA Polyadenylation and Deadenylation.
Autorzy:
Liu J; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Lu X; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Zhang S; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Yuan L; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Sun Y; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 20; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Polyadenylation*
Saccharomyces cerevisiae Proteins*/metabolism
DNA-Binding Proteins/metabolism ; Exoribonucleases/genetics ; Humans ; Multiprotein Complexes/metabolism ; Poly(A)-Binding Proteins/metabolism ; RNA Precursors/metabolism ; RNA Stability ; RNA, Messenger/metabolism ; Saccharomyces cerevisiae/metabolism ; Ubiquitin-Protein Ligases/metabolism ; mRNA Cleavage and Polyadenylation Factors/metabolism
Czasopismo naukowe
Tytuł:
Chemically Modified Poly(A) Analogs Targeting PABP: Structure Activity Relationship and Translation Inhibitory Properties.
Autorzy:
Perzanowska O; Division of Biophysics, Faculty of Physics, University of Warsaw, Ludwika Pasteura 5, 02-093, Warsaw, Poland.; Centre of New Technologies, University of Warsaw, Stefana Banacha 2c, 02-097, Warsaw, Poland.
Smietanski M; Centre of New Technologies, University of Warsaw, Stefana Banacha 2c, 02-097, Warsaw, Poland.
Jemielity J; Centre of New Technologies, University of Warsaw, Stefana Banacha 2c, 02-097, Warsaw, Poland.
Kowalska J; Division of Biophysics, Faculty of Physics, University of Warsaw, Ludwika Pasteura 5, 02-093, Warsaw, Poland.
Pokaż więcej
Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Jul 26; Vol. 28 (42), pp. e202201115. Date of Electronic Publication: 2022 Jun 10.
Typ publikacji:
Journal Article
MeSH Terms:
Poly A*/metabolism
Protein Biosynthesis*
Animals ; Ligands ; Poly(A)-Binding Proteins/chemistry ; Poly(A)-Binding Proteins/genetics ; Poly(A)-Binding Proteins/metabolism ; Protein Binding ; RNA/metabolism ; RNA, Messenger/metabolism ; Rabbits ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Dynamic interaction of poly(A)-binding protein with the ribosome.
Autorzy:
Machida K; Department of Applied Chemistry, Graduate School of Engineering, University of Hyogo, Himeji, 671-2201, Japan.
Shigeta T; Department of Applied Chemistry, Graduate School of Engineering, University of Hyogo, Himeji, 671-2201, Japan.
Yamamoto Y; Department of Applied Chemistry, Graduate School of Engineering, University of Hyogo, Himeji, 671-2201, Japan.
Ito T; Division of Structural and Synthetic Biology, RIKEN Center for Life Science Technologies, and Laboratory for Translation Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama, 230-0045, Japan.
Svitkin Y; Department of Biochemistry and Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, H3A 1A3, Canada.
Sonenberg N; Department of Biochemistry and Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, H3A 1A3, Canada.
Imataka H; Department of Applied Chemistry, Graduate School of Engineering, University of Hyogo, Himeji, 671-2201, Japan. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2018 Nov 28; Vol. 8 (1), pp. 17435. Date of Electronic Publication: 2018 Nov 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Poly(A)-Binding Proteins/*metabolism
Ribosomes/*metabolism
Amino Acid Sequence ; Binding Sites ; Cell Line ; Eukaryotic Initiation Factor-4F ; Eukaryotic Initiation Factor-4G/metabolism ; Humans ; Models, Molecular ; Molecular Conformation ; Poly(A)-Binding Proteins/chemistry ; Poly(A)-Binding Proteins/genetics ; Protein Binding ; Protein Biosynthesis ; RNA, Messenger/chemistry ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Recombinant Proteins/metabolism ; Ribosomes/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
lncRNA GHET1 Promotes the Progression of Triple-Negative Breast Cancer via Regulation of miR-377-3p/GRSF1 Signaling Axis.
Autorzy:
Wang Y; Molecular Testing Center, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning Province 121000, China.
Li C; Molecular Testing Center, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning Province 121000, China.
Pokaż więcej
Źródło:
Computational and mathematical methods in medicine [Comput Math Methods Med] 2022 Apr 25; Vol. 2022, pp. 8366569. Date of Electronic Publication: 2022 Apr 25 (Print Publication: 2022).
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Triple Negative Breast Neoplasms*/genetics
Triple Negative Breast Neoplasms*/pathology
Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 9/metabolism ; Poly(A)-Binding Proteins/genetics ; Poly(A)-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł:
GRSF1 is an age-related regulator of senescence.
Autorzy:
Kim SJ; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA.
Chun M; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA.
Wan J; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA.
Lee C; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA.
Yen K; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA.
Cohen P; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2019 Apr 03; Vol. 9 (1), pp. 5546. Date of Electronic Publication: 2019 Apr 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Aging/*physiology
Cellular Senescence/*physiology
Poly(A)-Binding Proteins/*genetics
Animals ; Cells, Cultured ; DNA Methylation ; Female ; Gene Expression Regulation ; Gene Knockdown Techniques ; Humans ; Male ; Mice, Inbred C57BL ; Muscle, Skeletal/cytology ; Muscle, Skeletal/physiology ; Poly(A)-Binding Proteins/metabolism ; Promoter Regions, Genetic
Czasopismo naukowe
Tytuł:
Toxoplasma gondii infection induces the formation of host's nuclear granules containing poly(A)-binding proteins.
Autorzy:
Fischer K; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Roberts M; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Roscoe S; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Avci Y; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Ananvoranich S; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.; Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Pokaż więcej
Źródło:
Canadian journal of microbiology [Can J Microbiol] 2018 Aug; Vol. 64 (8), pp. 551-558. Date of Electronic Publication: 2018 Apr 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Nucleus/*chemistry
Poly(A)-Binding Proteins/*ultrastructure
Toxoplasma/*physiology
Toxoplasmosis/*pathology
Animals ; Biological Transport/drug effects ; Cell Nucleus/metabolism ; Host-Parasite Interactions/drug effects ; Humans ; Poly(A)-Binding Proteins/metabolism ; Pyrimethamine/pharmacology ; Toxoplasma/drug effects ; Toxoplasmosis/parasitology
Czasopismo naukowe
Tytuł:
The RNA-binding protein GRSF1 promotes hepatocarcinogenesis via competitively binding to YY1 mRNA with miR-30e-5p.
Autorzy:
Han L; Department of Oncology, The Second Affiliated Hospital, College of Medicine, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi, China. .
Huang C; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education of China, Xi'an Jiaotong University, No.277 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.
Wang X; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education of China, Xi'an Jiaotong University, No.277 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.
Tong D; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education of China, Xi'an Jiaotong University, No.277 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.
Pokaż więcej
Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2022 Jan 08; Vol. 41 (1), pp. 17. Date of Electronic Publication: 2022 Jan 08.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular/*genetics
Liver Neoplasms/*genetics
MicroRNAs/*metabolism
RNA, Messenger/*metabolism
YY1 Transcription Factor/*metabolism
Animals ; Apoptosis ; Carcinoma, Hepatocellular/pathology ; Humans ; Liver Neoplasms/pathology ; Male ; Mice ; Poly(A)-Binding Proteins ; Transfection
Czasopismo naukowe
Tytuł:
Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis.
Autorzy:
Pandey PR; National Centre for Cell Science, Ganeshkhind, Pune, India.; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune, India.
Sarwade RD; National Centre for Cell Science, Ganeshkhind, Pune, India.; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune, India.
Khalique A; National Centre for Cell Science, Ganeshkhind, Pune, India.; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune, India.
Seshadri V; National Centre for Cell Science, Ganeshkhind, Pune, India.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2018 Mar 28; Vol. 13 (3), pp. e0194482. Date of Electronic Publication: 2018 Mar 28 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
5' Untranslated Regions*
Peptide Chain Initiation, Translational*
ELAV-Like Protein 4/*metabolism
Insulin/*biosynthesis
Poly(A)-Binding Proteins/*metabolism
Animals ; Cell Line ; ELAV-Like Protein 4/genetics ; Insulin/genetics ; Mice ; Poly(A)-Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
Ribosome-bound Pub1 modulates stop codon decoding during translation termination in yeast.
Autorzy:
Urakov VN; Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Bach Institute of Biochemistry, Moscow, Russia.
Mitkevich OV; Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Bach Institute of Biochemistry, Moscow, Russia.
Safenkova IV; Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Bach Institute of Biochemistry, Moscow, Russia.
Ter-Avanesyan MD; Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Bach Institute of Biochemistry, Moscow, Russia.
Pokaż więcej
Źródło:
The FEBS journal [FEBS J] 2017 Jun; Vol. 284 (12), pp. 1914-1930. Date of Electronic Publication: 2017 May 29.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Termination Factors/*metabolism
Poly(A)-Binding Proteins/*metabolism
Ribosomes/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Codon, Terminator ; Peptide Chain Termination, Translational ; Peptide Termination Factors/genetics ; Poly(A)-Binding Proteins/genetics ; Ribosomes/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae Proteins/genetics ; Sequence Deletion
Czasopismo naukowe
Tytuł:
The Role of Methionine Residues in the Regulation of Liquid-Liquid Phase Separation.
Autorzy:
Aledo JC; Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2021 Aug 21; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Liquid-Liquid Extraction*
Protein Processing, Post-Translational*
Methionine/*chemistry
Animals ; Ataxin-2/metabolism ; DNA-Binding Proteins/chemistry ; Humans ; Molecular Dynamics Simulation ; Organelles/chemistry ; Poly(A)-Binding Proteins/chemistry ; Protein Domains ; Proteins/chemistry ; RNA/metabolism ; Saccharomyces cerevisiae Proteins/chemistry
Czasopismo naukowe
Tytuł:
Mitochondrial ubiquitin ligase alleviates Alzheimer's disease pathology via blocking the toxic amyloid-β oligomer generation.
Autorzy:
Takeda K; Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.; Department of Biology, University of Padova, Padova, Italy.; Venetian Institute of Molecular Medicine, Padova, Italy.
Uda A; Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Mitsubori M; Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Nagashima S; Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Iwasaki H; Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Ito N; Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.; Laboratory of Molecular Biochemistry, Department of Life Science, Faculty of Science, Gakushuin University, Toshima-ku, Tokyo, Japan.
Shiiba I; Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.; Laboratory of Molecular Biochemistry, Department of Life Science, Faculty of Science, Gakushuin University, Toshima-ku, Tokyo, Japan.
Ishido S; Department of Microbiology, Hyogo College of Medicine, Nishinomiya, Japan.
Matsuoka M; Department of Pharmacology, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.
Inatome R; Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.; Laboratory of Molecular Biochemistry, Department of Life Science, Faculty of Science, Gakushuin University, Toshima-ku, Tokyo, Japan.
Yanagi S; Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan. .; Laboratory of Molecular Biochemistry, Department of Life Science, Faculty of Science, Gakushuin University, Toshima-ku, Tokyo, Japan. .
Pokaż więcej
Źródło:
Communications biology [Commun Biol] 2021 Feb 12; Vol. 4 (1), pp. 192. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease/*enzymology
Amyloid beta-Peptides/*metabolism
Brain/*enzymology
Mitochondria/*enzymology
Mitochondrial Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Alzheimer Disease/psychology ; Animals ; Behavior, Animal ; Blood Proteins/genetics ; Blood Proteins/metabolism ; Brain/pathology ; Cell Line, Tumor ; Cognition ; Disease Models, Animal ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice, Knockout ; Mitochondria/genetics ; Mitochondria/pathology ; Mitochondrial Proteins/genetics ; Plaque, Amyloid ; Poly(A)-Binding Proteins/genetics ; Poly(A)-Binding Proteins/metabolism ; Presenilin-1/genetics ; Presenilin-1/metabolism ; Protein Aggregates ; Protein Aggregation, Pathological ; Ubiquitin-Protein Ligases/genetics ; Mice
Czasopismo naukowe
Tytuł:
miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1.
Autorzy:
Liu Y; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China.
Liu R; Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.
Yang F; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China.
Cheng R; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China.
Chen X; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China.
Cui S; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China.
Gu Y; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China.
Sun W; Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.
You C; Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.
Liu Z; Department of Gastrointestinal Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, 321 Zhongshan Road, Nanjing, Jiangsu, 210008, China.
Sun F; Department of Gastrointestinal Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, 321 Zhongshan Road, Nanjing, Jiangsu, 210008, China.
Wang Y; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China.
Fu Z; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China.
Ye C; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China.
Zhang C; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China. .
Li J; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China. .
Chen X; State Key Laboratory of Pharmaceutical Biotechnology, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing, Jiangsu, 210046, China. .
Pokaż więcej
Źródło:
Molecular cancer [Mol Cancer] 2017 Mar 04; Vol. 16 (1), pp. 53. Date of Electronic Publication: 2017 Mar 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms/*genetics
MicroRNAs/*genetics
Poly(A)-Binding Proteins/*genetics
3' Untranslated Regions ; Animals ; Apoptosis Regulatory Proteins/genetics ; Binding Sites ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Disease Models, Animal ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Genes, myc ; Heterografts ; Humans ; Male ; Meta-Analysis as Topic ; Mice ; Poly(A)-Binding Proteins/metabolism ; RNA Interference ; RNA Processing, Post-Transcriptional ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA-Binding Proteins/genetics ; T-Cell Intracellular Antigen-1
Czasopismo naukowe
Tytuł:
Harnessing short poly(A)-binding protein-interacting peptides for the suppression of nonsense-mediated mRNA decay.
Autorzy:
Fatscher T; Institute for Genetics, University of Cologne, Cologne, Germany.
Gehring NH; Institute for Genetics, University of Cologne, Cologne, Germany.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2016 Nov 22; Vol. 6, pp. 37311. Date of Electronic Publication: 2016 Nov 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nonsense Mediated mRNA Decay/*genetics
Peptides/*genetics
Poly(A)-Binding Proteins/*genetics
RNA, Messenger/*genetics
3' Untranslated Regions/genetics ; Codon, Nonsense/genetics ; HeLa Cells ; Humans ; Peptide Termination Factors/genetics ; Peptide Termination Factors/metabolism ; Peptides/metabolism ; Poly(A)-Binding Protein I/genetics ; Poly(A)-Binding Protein I/metabolism ; Poly(A)-Binding Proteins/metabolism ; Protein Binding ; Protein Biosynthesis/genetics ; RNA Interference ; RNA, Messenger/metabolism ; beta-Globins/genetics ; beta-Globins/metabolism
Czasopismo naukowe
Tytuł:
RNA binding protein Pub1p regulates glycerol production and stress tolerance by controlling Gpd1p activity during winemaking.
Autorzy:
Orozco H; Departament de Bioquímica i Biologia Molecular, Universitat de València, Valencia, Spain. .; Departamento de Biotecnología, Instituto de Agroquímica y Tecnología de Alimentos, IATA-CSIC, Avda. Agustín Escardino, 7, 46980, Paterna, Spain. .
Sepúlveda A; Departament de Bioquímica i Biologia Molecular, Universitat de València, Valencia, Spain.; Departamento de Biotecnología, Instituto de Agroquímica y Tecnología de Alimentos, IATA-CSIC, Avda. Agustín Escardino, 7, 46980, Paterna, Spain.
Picazo C; Departament de Bioquímica i Biologia Molecular, Universitat de València, Valencia, Spain.; Departamento de Biotecnología, Instituto de Agroquímica y Tecnología de Alimentos, IATA-CSIC, Avda. Agustín Escardino, 7, 46980, Paterna, Spain.
Matallana E; Departament de Bioquímica i Biologia Molecular, Universitat de València, Valencia, Spain.; Departamento de Biotecnología, Instituto de Agroquímica y Tecnología de Alimentos, IATA-CSIC, Avda. Agustín Escardino, 7, 46980, Paterna, Spain.
Aranda A; Departamento de Biotecnología, Instituto de Agroquímica y Tecnología de Alimentos, IATA-CSIC, Avda. Agustín Escardino, 7, 46980, Paterna, Spain.
Pokaż więcej
Źródło:
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2016 Jun; Vol. 100 (11), pp. 5017-27. Date of Electronic Publication: 2016 Feb 04.
Typ publikacji:
Journal Article
MeSH Terms:
Glycerol/*metabolism
Glycerol-3-Phosphate Dehydrogenase (NAD+)/*metabolism
Poly(A)-Binding Proteins/*metabolism
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*metabolism
Wine/*analysis
Fermentation ; Food Handling ; Fruit and Vegetable Juices/microbiology ; Gene Expression Regulation, Fungal ; Glycerol-3-Phosphate Dehydrogenase (NAD+)/genetics ; Glycerolphosphate Dehydrogenase/genetics ; Glycerolphosphate Dehydrogenase/metabolism ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Osmotic Pressure ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Poly(A)-Binding Proteins/genetics ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Stress, Physiological ; Vitis/microbiology ; Wine/microbiology
Czasopismo naukowe
Tytuł:
Characterization of ALBA Family Expression and Localization in Arabidopsis thaliana Generative Organs.
Autorzy:
Náprstková A; Laboratory of Pollen Biology, Institute of Experimental Botany of the Czech Academy of Sciences, Rozvojová 263, 165 02 Prague 6, Czech Republic.
Malínská K; Imaging Facility, Institute of Experimental Botany of the Czech Academy of Sciences, Rozvojová 263, 165 02 Prague 6, Czech Republic.
Záveská Drábková L; Laboratory of Pollen Biology, Institute of Experimental Botany of the Czech Academy of Sciences, Rozvojová 263, 165 02 Prague 6, Czech Republic.
Billey E; CNRS LGDP-UMR5096, 58 Av. Paul Alduy, 66860 Perpignan, France.; LGDP-UMR5096, Université de Perpignan via Domitia, 58 Av. Paul Alduy, 66860 Perpignan, France.
Náprstková D; Laboratory of Pollen Biology, Institute of Experimental Botany of the Czech Academy of Sciences, Rozvojová 263, 165 02 Prague 6, Czech Republic.
Sýkorová E; Institute of Biophysics of the Czech Academy of Sciences, Královopolská, 612 00 Brno, Czech Republic.
Bousquet-Antonelli C; CNRS LGDP-UMR5096, 58 Av. Paul Alduy, 66860 Perpignan, France.; LGDP-UMR5096, Université de Perpignan via Domitia, 58 Av. Paul Alduy, 66860 Perpignan, France.
Honys D; Laboratory of Pollen Biology, Institute of Experimental Botany of the Czech Academy of Sciences, Rozvojová 263, 165 02 Prague 6, Czech Republic.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 06; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Arabidopsis/*embryology
Arabidopsis Proteins/*metabolism
Pollen/*embryology
RNA-Binding Proteins/*metabolism
Arabidopsis/metabolism ; Arabidopsis Proteins/genetics ; Flowers/growth & development ; Gene Expression Regulation, Plant/genetics ; Heat-Shock Response/physiology ; Microscopy, Confocal ; Poly(A)-Binding Proteins/metabolism ; Promoter Regions, Genetic/genetics ; RNA-Binding Proteins/genetics ; Stress, Physiological/genetics
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies