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Wyświetlanie 1-10 z 343
Tytuł:
RNA Binding Protein PTBP1 Promotes the Metastasis of Gastric Cancer by Stabilizing PGK1 mRNA.
Autorzy:
Wang X; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Liang C; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Wang S; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Ma Q; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Pan X; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Ran A; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Qin C; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Huang B; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi 563006, China.
Yang F; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Liu Y; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Zhang Y; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Ren J; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Ning H; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Li H; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Jiang Y; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Xiao B; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
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Źródło:
Cells [Cells] 2024 Jan 12; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Stomach Neoplasms*/genetics
Polypyrimidine Tract-Binding Protein*/genetics
Polypyrimidine Tract-Binding Protein*/metabolism
Phosphoglycerate Kinase*/genetics
Animals ; Mice ; Mice, Nude ; RNA, Messenger/genetics ; RNA-Binding Proteins ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reviewing PTBP1 Domain Modularity in the Pre-Genomic Era: A Foundation to Guide the Next Generation of Exploring PTBP1 Structure-Function Relationships.
Autorzy:
Carico C; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Placzek WJ; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 07; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Polypyrimidine Tract-Binding Protein*/genetics
Polypyrimidine Tract-Binding Protein*/metabolism
Heterogeneous-Nuclear Ribonucleoproteins*/genetics
Heterogeneous-Nuclear Ribonucleoproteins*/metabolism
RNA/metabolism ; Genomics ; Structure-Activity Relationship ; Alternative Splicing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site.
Autorzy:
Angulo J; Laboratorio de Virología Molecular, Centro de Investigaciones Médicas, Instituto Milenio de Inmunología e Inmunoterapia, Departamento de Enfermedades Infecciosas e Inmunología Pediátrica, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8330024, Chile.; Facultad de Odontología, Universidad Finis Terrae, Santiago 7501015, Chile.
Cáceres CJ; Laboratorio de Virología Molecular, Centro de Investigaciones Médicas, Instituto Milenio de Inmunología e Inmunoterapia, Departamento de Enfermedades Infecciosas e Inmunología Pediátrica, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8330024, Chile.; Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Contreras N; Laboratorio de Virología Molecular, Centro de Investigaciones Médicas, Instituto Milenio de Inmunología e Inmunoterapia, Departamento de Enfermedades Infecciosas e Inmunología Pediátrica, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8330024, Chile.; Facultad de Medicina Veterinaria y Agronomía, Universidad de Las Américas, Santiago 7500975, Chile.
Fernández-García L; Laboratorio de Virología Molecular, Centro de Investigaciones Médicas, Instituto Milenio de Inmunología e Inmunoterapia, Departamento de Enfermedades Infecciosas e Inmunología Pediátrica, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8330024, Chile.
Chamond N; Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8038, Laboratoire CiTCoM, Université Paris Cité, 75006 Paris, France.
Ameur M; Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8038, Laboratoire CiTCoM, Université Paris Cité, 75006 Paris, France.
Sargueil B; Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8038, Laboratoire CiTCoM, Université Paris Cité, 75006 Paris, France.
López-Lastra M; Laboratorio de Virología Molecular, Centro de Investigaciones Médicas, Instituto Milenio de Inmunología e Inmunoterapia, Departamento de Enfermedades Infecciosas e Inmunología Pediátrica, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8330024, Chile.
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Źródło:
Viruses [Viruses] 2022 Dec 20; Vol. 15 (1). Date of Electronic Publication: 2022 Dec 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hepatitis C*/genetics
Polypyrimidine Tract-Binding Protein*/genetics
Polypyrimidine Tract-Binding Protein*/chemistry
Polypyrimidine Tract-Binding Protein*/metabolism
Humans ; 5' Untranslated Regions ; HEK293 Cells ; Hepacivirus/genetics ; Hepacivirus/metabolism ; Internal Ribosome Entry Sites ; Protein Biosynthesis ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; RNA, Viral/genetics ; RNA, Viral/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
PRP8-Induced CircMaml2 Facilitates the Healing of the Intestinal Mucosa via Recruiting PTBP1 and Regulating Sec62.
Autorzy:
Deng Y; Department of Burn Surgery, The Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou 221004, China.; Department of Burn Surgery, The 71st Group Army Hospital of PLA, Xuzhou 221004, China.
Xu X; Department of Burn Surgery, The Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou 221004, China.; Department of Burn Surgery, The 71st Group Army Hospital of PLA, Xuzhou 221004, China.
Meng F; Department of Burn Surgery, The Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou 221004, China.; Department of Burn Surgery, The 71st Group Army Hospital of PLA, Xuzhou 221004, China.
Lou J; Department of Burn Surgery, The Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou 221004, China.; Department of Burn Surgery, The 71st Group Army Hospital of PLA, Xuzhou 221004, China.
Liao Y; Department of Burn Surgery, The Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou 221004, China.; Department of Burn Surgery, The 71st Group Army Hospital of PLA, Xuzhou 221004, China.
Li Q; Department of Burn Surgery, The Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou 221004, China.; Department of Burn Surgery, The 71st Group Army Hospital of PLA, Xuzhou 221004, China.
Zhuang M; Department of Burn Surgery, The Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou 221004, China.; Department of Burn Surgery, The 71st Group Army Hospital of PLA, Xuzhou 221004, China.
Sun Y; Department of Burn Surgery, The Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou 221004, China.; Department of Burn Surgery, The 71st Group Army Hospital of PLA, Xuzhou 221004, China.
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Źródło:
Cells [Cells] 2022 Nov 01; Vol. 11 (21). Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Polypyrimidine Tract-Binding Protein*/genetics
Polypyrimidine Tract-Binding Protein*/metabolism
MicroRNAs*/genetics
Mice ; Animals ; Heterogeneous-Nuclear Ribonucleoproteins/genetics ; Heterogeneous-Nuclear Ribonucleoproteins/metabolism ; RNA, Circular/genetics ; Transcription Factors/metabolism ; Intestinal Mucosa/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
KLF15 transcriptionally activates LINC00689 to inhibit colorectal cancer development.
Autorzy:
Cao Y; Department of Nuclear Medicine, Xiangya Third Hospital, Central South University, Changsha, 410013, Hunan Province, PR China.
Li J; Department of Nuclear Medicine, Xiangya Third Hospital, Central South University, Changsha, 410013, Hunan Province, PR China.
Zhang G; Department 2 of Gastrointestinal Surgery, Haikou Hospital Affiliated to Xiangya Medical College of Central South University, Haikou People's Hospital, Haikou, 570208, Hainan Province, PR China.
Fang H; Department of Nuclear Medicine, Xiangya Third Hospital, Central South University, Changsha, 410013, Hunan Province, PR China.
Du Y; Department of Nuclear Medicine, Xiangya Third Hospital, Central South University, Changsha, 410013, Hunan Province, PR China.
Liang Y; Department of Nuclear Medicine, Xiangya Third Hospital, Central South University, Changsha, 410013, Hunan Province, PR China. .
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Źródło:
Communications biology [Commun Biol] 2024 Jan 25; Vol. 7 (1), pp. 130. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
beta Catenin*/metabolism
Colorectal Neoplasms*/metabolism
Humans ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Protein Serine-Threonine Kinases/metabolism ; Tumor Suppressor Proteins/genetics ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism ; Heterogeneous-Nuclear Ribonucleoproteins/genetics ; Heterogeneous-Nuclear Ribonucleoproteins/metabolism ; Polypyrimidine Tract-Binding Protein/genetics ; Polypyrimidine Tract-Binding Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
FMRP deficiency leads to multifactorial dysregulation of splicing and mislocalization of MBNL1 to the cytoplasm.
Autorzy:
Jung S; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America.
Shah S; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America.
Han G; Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, United States of America.
Richter JD; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2023 Dec 04; Vol. 21 (12), pp. e3002417. Date of Electronic Publication: 2023 Dec 04 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Fragile X Mental Retardation Protein*/genetics
RNA Splicing*/genetics
Animals ; Humans ; Mice ; Cytoplasm/metabolism ; Heterogeneous-Nuclear Ribonucleoproteins/genetics ; Heterogeneous-Nuclear Ribonucleoproteins/metabolism ; Polypyrimidine Tract-Binding Protein/genetics ; Polypyrimidine Tract-Binding Protein/metabolism ; Protein Isoforms/metabolism ; RNA/metabolism ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CircPPAP2B controls metastasis of clear cell renal cell carcinoma via HNRNPC-dependent alternative splicing and targeting the miR-182-5p/CYP1B1 axis.
Autorzy:
Zheng Z; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zeng X; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zhu Y; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Leng M; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zhang Z; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Wang Q; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Liu X; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zeng S; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Xiao Y; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Hu C; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Pang S; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Wang T; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Xu B; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Peng P; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Li F; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China. .
Tan W; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2024 Jan 06; Vol. 23 (1), pp. 4. Date of Electronic Publication: 2024 Jan 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Renal Cell*/genetics
MicroRNAs*/genetics
Kidney Neoplasms*/genetics
Humans ; Alternative Splicing ; RNA, Circular/genetics ; Heterogeneous-Nuclear Ribonucleoproteins ; Polypyrimidine Tract-Binding Protein ; Cytochrome P-450 CYP1B1 ; Heterogeneous-Nuclear Ribonucleoprotein Group C/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LPS Administration Impacts Glial Immune Programs by Alternative Splicing.
Autorzy:
Babenko VN; Laboratory of Functional Neurogenomics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, 630090 Novosibirsk, Russia.
Shishkina GT; Laboratory of Functional Neurogenomics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, 630090 Novosibirsk, Russia.
Lanshakov DA; Laboratory of Functional Neurogenomics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, 630090 Novosibirsk, Russia.
Sukhareva EV; Laboratory of Functional Neurogenomics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, 630090 Novosibirsk, Russia.
Dygalo NN; Laboratory of Functional Neurogenomics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, 630090 Novosibirsk, Russia.
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Źródło:
Biomolecules [Biomolecules] 2022 Feb 08; Vol. 12 (2). Date of Electronic Publication: 2022 Feb 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alternative Splicing*
Polypyrimidine Tract-Binding Protein*/genetics
Polypyrimidine Tract-Binding Protein*/metabolism
Exons ; Heterogeneous-Nuclear Ribonucleoproteins/genetics ; Heterogeneous-Nuclear Ribonucleoproteins/metabolism ; Lipopolysaccharides/pharmacology ; Neuroglia/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement.
Autorzy:
Zhang C; Research Center, the Fourth Hospital of Hebei Medical University, Jiankang Road 12, Shijiazhuang, 050011, Hebei, China.; Key Laboratory of Tumor Gene Diagnosis, Prevention and Therapy; Clinical Oncology Research Center, Shijiazhuang, 050001, Hebei, China.
Wang H; Research Center, the Fourth Hospital of Hebei Medical University, Jiankang Road 12, Shijiazhuang, 050011, Hebei, China.; Key Laboratory of Tumor Gene Diagnosis, Prevention and Therapy; Clinical Oncology Research Center, Shijiazhuang, 050001, Hebei, China.
Liu Q; Third Department of Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Dai S; Research Center, the Fourth Hospital of Hebei Medical University, Jiankang Road 12, Shijiazhuang, 050011, Hebei, China.; Key Laboratory of Tumor Gene Diagnosis, Prevention and Therapy; Clinical Oncology Research Center, Shijiazhuang, 050001, Hebei, China.
Tian G; Medical Records Department, the Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Wei X; Research Center, the Fourth Hospital of Hebei Medical University, Jiankang Road 12, Shijiazhuang, 050011, Hebei, China.; Key Laboratory of Tumor Gene Diagnosis, Prevention and Therapy; Clinical Oncology Research Center, Shijiazhuang, 050001, Hebei, China.
Li X; Research Center, the Fourth Hospital of Hebei Medical University, Jiankang Road 12, Shijiazhuang, 050011, Hebei, China.; Key Laboratory of Tumor Gene Diagnosis, Prevention and Therapy; Clinical Oncology Research Center, Shijiazhuang, 050001, Hebei, China.
Zhao L; Research Center, the Fourth Hospital of Hebei Medical University, Jiankang Road 12, Shijiazhuang, 050011, Hebei, China. .; Key Laboratory of Tumor Gene Diagnosis, Prevention and Therapy; Clinical Oncology Research Center, Shijiazhuang, 050001, Hebei, China. .
Shan B; Research Center, the Fourth Hospital of Hebei Medical University, Jiankang Road 12, Shijiazhuang, 050011, Hebei, China. .; Key Laboratory of Tumor Gene Diagnosis, Prevention and Therapy; Clinical Oncology Research Center, Shijiazhuang, 050001, Hebei, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Sep 23; Vol. 42 (1), pp. 246. Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:
Journal Article
MeSH Terms:
Stomach Neoplasms*/genetics
RNA, Long Noncoding*/genetics
Animals ; Mice ; Humans ; Mice, Nude ; Carcinogenesis ; Glycolysis ; Heterogeneous-Nuclear Ribonucleoproteins/genetics ; Polypyrimidine Tract-Binding Protein/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Unraveling the link between PTBP1 and severe asthma through machine learning and association rule mining method.
Autorzy:
Pirmoradi S; Clinical Research Development Unit of Tabriz Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Hosseiniyan Khatibi SM; Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Rahat Breath and Sleep Research Center, Tabriz University of Medical Science, Tabriz, Iran.
Zununi Vahed S; Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Homaei Rad H; Rahat Breath and Sleep Research Center, Tabriz University of Medical Science, Tabriz, Iran.
Khamaneh AM; Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Akbarpour Z; Rahat Breath and Sleep Research Center, Tabriz University of Medical Science, Tabriz, Iran.
Seyedrezazadeh E; Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Teshnehlab M; Department of Electric and Computer Engineering, K.N. Toosi University of Technology, Tehran, Iran.
Chapman KR; Division of Respiratory Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada. .
Ansarin K; Rahat Breath and Sleep Research Center, Tabriz University of Medical Science, Tabriz, Iran. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 16; Vol. 13 (1), pp. 15399. Date of Electronic Publication: 2023 Sep 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Artificial Intelligence*
Asthma*/genetics
Humans ; Machine Learning ; Data Mining ; Heterogeneous-Nuclear Ribonucleoproteins/genetics ; Polypyrimidine Tract-Binding Protein/genetics
SCR Disease Name:
Pulmonary Disease, Chronic Obstructive, Severe Early-Onset
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-10 z 343

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