Investigation of the effects of mTOR inhibitors rapamycin and everolimus in combination with carboplatin on canine malignant melanoma cells.
Autorzy:
Bernard S; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada. PoonAC; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada. Tam PM; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada. Mutsaers AJ; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada. .; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada. .
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Źródło:
BMC veterinary research [BMC Vet Res] 2021 Dec 11; Vol. 17 (1), pp. 382. Date of Electronic Publication: 2021 Dec 11.
Inhibition of copper chaperones sensitizes human and canine osteosarcoma cells to carboplatin chemotherapy.
Autorzy:
Inkol JM; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada. PoonAC; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada. Mutsaers AJ; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
An evaluation of TAZ and YAP crosstalk with TGFβ signalling in canine osteosarcoma suggests involvement of hippo signalling in disease progression.
Autorzy:
Luu AK; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. Schott CR; Department of Pathobiology, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. Jones R; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. PoonAC; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. Golding B; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. Hamed R; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. Deheshi B; Medical City Forth Worth, HCA affiliated Hospital, 900 8th Ave, Fort Worth, TX, 76104, USA. Mutsaers A; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. Wood GA; Department of Pathobiology, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. . Viloria-Petit AM; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. .
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Źródło:
BMC veterinary research [BMC Vet Res] 2018 Nov 26; Vol. 14 (1), pp. 365. Date of Electronic Publication: 2018 Nov 26.
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