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Tytuł:
Utilization of Bacteriophage phi6 for the Production of High-Quality Double-Stranded RNA Molecules.
Autorzy:
Levanova AA; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland.
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Źródło:
Viruses [Viruses] 2024 Jan 22; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
RNA, Double-Stranded*/genetics
RNA-Dependent RNA Polymerase*/genetics
RNA-Dependent RNA Polymerase*/metabolism
RNA Interference ; Nucleotidyltransferases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Diversity and Current Classification of dsRNA Bacteriophages.
Autorzy:
Mäntynen S; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland.
Salomaa MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland.
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Źródło:
Viruses [Viruses] 2023 Oct 25; Vol. 15 (11). Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Bacteriophages*/genetics
Pseudomonas Phages*/genetics
Pseudomonas ; Genome, Viral
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Four principles to establish a universal virus taxonomy.
Autorzy:
Simmonds P; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Adriaenssens EM; Quadram Institute Bioscience, Norwich Research Park, Norwich, United Kingdom.
Zerbini FM; Departamento de Fitopatologia/BIOAGRO, Universidade Federal de Viçosa, Viçosa, Brazil.
Abrescia NGA; Structure and Cell Biology of Viruses Lab, Center for Cooperative Research in Biosciences-BRTA, Derio, Spain.; Basque Foundation for Science, IKERBASQUE, Bilbao, Spain.
Aiewsakun P; Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Alfenas-Zerbini P; Departamento de Microbiologia/BIOAGRO, Universidade Federal de Viçosa, Viçosa, Brazil.
Bao Y; National Genomics Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Barylski J; Department of Molecular Virology, Adam Mickiewicz University, Poznan, Poland.
Drosten C; Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Free University Berlin, Humboldt University, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany.
Duffy S; Department of Ecology, Evolution and Natural Resources, School of Environmental and Biological Sciences, Rutgers The State University of New Jersey, New Brunswick, New Jersey, United States of America.
Duprex WP; The Center for Vaccine Research, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Dutilh BE; Institute of Biodiversity, Faculty of Biological Sciences, Cluster of Excellence Balance of the Microverse, Friedrich-Schiller-University, Jena, Germany.; Theoretical Biology and Bioinformatics, Science for Life, Utrecht University, Utrecht, the Netherlands.
Elena SF; Instituto de Biología Integrativa de Sistemas (I2SysBio), CSIC-Universitat de València, Valencia, Spain.; Santa Fe Institute, Santa Fe, New Mexico, United States of America.
García ML; Instituto de Biotecnología y Biología Molecular, CCT-La Plata, CONICET, UNLP, La Plata, Argentina.
Junglen S; Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Free University Berlin, Humboldt University, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany.
Katzourakis A; Department of Biology, University of Oxford, Oxford, United Kingdom.
Koonin EV; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America.
Krupovic M; Institut Pasteur, Université Paris Cité, CNRS UMR6047, Archaeal Virology Unit, Paris, France.
Kuhn JH; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, United States of America.
Lambert AJ; Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, United States of America.
Lefkowitz EJ; Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Łobocka M; Institute of Biochemistry and Biophysics of the Polish Academy of Sciences, Warsaw, Poland.
Lood C; Department of Biosystems, KU Leuven, Leuven, Belgium.
Mahony J; School of Microbiology and APC Microbiome Ireland, University College Cork, Cork, Ireland.
Meier-Kolthoff JP; Department of Bioinformatics and Databases, Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany.
Mushegian AR; Division of Molecular and Cellular Biosciences, National Science Foundation, Alexandria, Virginia, United States of America.
Oksanen HM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Reyes-Muñoz A; Max Planck Tandem Group in Computational Biology, Departamento de Ciencias Biológicas, Universidad de los Andes, Bogotá, Colombia.
Robertson DL; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.
Roux S; Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America.
Rubino L; Istituto per la Protezione Sostenibile delle Piante, CNR, UOS Bari, Bari, Italy.
Sabanadzovic S; Department of Biochemistry, Molecular Biology, Entomology and Plant Pathology, Mississippi State University, Mississippi State, Mississippi, United States of America.
Siddell S; School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, United Kingdom.
Skern T; Medical University of Vienna, Max Perutz Labs, Vienna Biocenter, Vienna, Austria.
Smith DB; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Sullivan MB; Departments of Microbiology and Civil, Environmental, and Geodetic Engineering, Ohio State University, Columbus, Ohio, United States of America.
Suzuki N; Institute of Plant Science and Resources, Okayama University, Kurashiki, Okayama, Japan.
Turner D; School of Applied Sciences, College of Health, Science and Society, University of the West of England, Bristol, United Kingdom.
Van Doorslaer K; School of Animal and Comparative Biomedical Sciences, Department of Immunobiology, BIO5 Institute, and University of Arizona Cancer Center, Tucson, Arizona, United States of America.
Vandamme AM; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Leuven, Belgium.; Center for Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.
Varsani A; The Biodesign Center for Fundamental and Applied Microbiomics, School of Life Sciences, Center for Evolution and Medicine, Arizona State University, Tempe, Arizona, United States of America.
Vasilakis N; Department of Pathology, Center of Vector-Borne and Zoonotic Diseases, Institute for Human Infection and Immunity and World Reference Center for Emerging Viruses and Arboviruses, The University of Texas Medical Branch, Galveston, Texas, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2023 Feb 13; Vol. 21 (2), pp. e3001922. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Bacteriophages*
Viruses*/genetics
Humans ; Metagenomics ; Phylogeny
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells.
Autorzy:
Kalke K; Institute of Biomedicine, University of Turku, Turku, Finland.
Lund LM; Institute of Biomedicine, University of Turku, Turku, Finland.
Nyman MC; Institute of Biomedicine, University of Turku, Turku, Finland.
Levanova AA; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Urtti A; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.; Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Hukkanen V; Institute of Biomedicine, University of Turku, Turku, Finland.
Paavilainen H; Institute of Biomedicine, University of Turku, Turku, Finland.
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Źródło:
PLoS pathogens [PLoS Pathog] 2022 Jul 06; Vol. 18 (7), pp. e1010688. Date of Electronic Publication: 2022 Jul 06 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Herpes Simplex*/genetics
Herpes Simplex*/therapy
Herpesvirus 1, Human*/physiology
Acyclovir/metabolism ; Acyclovir/pharmacology ; Antiviral Agents/metabolism ; Antiviral Agents/pharmacology ; Epithelial Cells/metabolism ; Humans ; RNA, Double-Stranded/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Virus Replication/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Native RNA Purification Method for Small RNA Molecules Based on Asymmetrical Flow Field-Flow Fractionation.
Autorzy:
Levanova AA; Molecular and Integrative Biosciences Research Programme, Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9, FI-00014 Helsinki, Finland.
Lampi M; Molecular and Integrative Biosciences Research Programme, Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9, FI-00014 Helsinki, Finland.
Kalke K; Institute of Biomedicine, University of Turku, FI-20014 Turku, Finland.
Hukkanen V; Institute of Biomedicine, University of Turku, FI-20014 Turku, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9, FI-00014 Helsinki, Finland.
Eskelin K; Molecular and Integrative Biosciences Research Programme, Biological and Environmental Sciences, University of Helsinki, Viikinkaari 9, FI-00014 Helsinki, Finland.
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Źródło:
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2022 Feb 21; Vol. 15 (2). Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections.
Autorzy:
Ianevski A; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.
Yao R; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.
Zusinaite E; Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
Lello LS; Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
Wang S; Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
Jo E; Applied Molecular Virology Laboratory, Institut Pasteur Korea, Seongnam-si 463-400, Gyeonggi-do, Korea.
Yang J; Applied Molecular Virology Laboratory, Institut Pasteur Korea, Seongnam-si 463-400, Gyeonggi-do, Korea.
Ravlo E; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.
Wang W; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.
Lysvand H; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.
Løseth K; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.
Oksenych V; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.
Tenson T; Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
Windisch MP; Applied Molecular Virology Laboratory, Institut Pasteur Korea, Seongnam-si 463-400, Gyeonggi-do, Korea.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland.
Nieminen AI; Institute for Molecular Medicine Finland, University of Helsinki, 00014 Helsinki, Finland.
Nordbø SA; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.; Department of Medical Microbiology, St. Olavs Hospital, 7006 Trondheim, Norway.
Fenstad MH; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.; Department of Immunology and Transfusion Medicine, St. Olavs Hospital, 7006 Trondheim, Norway.
Grødeland G; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, 0372 Oslo, Norway.; Institute of Clinical Medicine (KlinMed), University of Oslo, 0318 Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, 0372 Oslo, Norway.
Aukrust P; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, 0372 Oslo, Norway.; Institute of Clinical Medicine (KlinMed), University of Oslo, 0318 Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, 0372 Oslo, Norway.
Trøseid M; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, 0372 Oslo, Norway.; Institute of Clinical Medicine (KlinMed), University of Oslo, 0318 Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, 0372 Oslo, Norway.
Kantele A; Inflammation Center, Infectious Diseases, Helsinki University Hospital, 00029 Helsinki, Finland.
Lastauskienė E; Life Sciences Center, Vilnius University, 10257 Vilnius, Lithuania.
Vitkauskienė A; Department of Laboratory Medicine, Lithuanian University of Health Science, 44307 Kaunas, Lithuania.
Legrand N; Oncodesign, 25 Avenue du Québec, 91140 Villebon Sur Yvette, France.
Merits A; Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
Bjørås M; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.
Kainov DE; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7028 Trondheim, Norway.; Institute of Technology, University of Tartu, 50411 Tartu, Estonia.; Institute for Molecular Medicine Finland, University of Helsinki, 00014 Helsinki, Finland.
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Źródło:
Viruses [Viruses] 2021 Dec 11; Vol. 13 (12). Date of Electronic Publication: 2021 Dec 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents/*pharmacology
Interferon-alpha/*pharmacology
SARS-CoV-2/*drug effects
Cell Line ; Drug Synergism ; Humans ; Lung/drug effects ; Lung/metabolism ; Lung/virology ; Metabolome/drug effects ; Organoids ; RNA, Viral/biosynthesis ; RNA, Viral/drug effects ; Signal Transduction/drug effects ; Transcriptome/drug effects ; Virus Replication/drug effects ; Viruses/classification ; Viruses/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
RNA-Dependent RNA Polymerase from Heterobasidion RNA Virus 6 Is an Active Replicase In Vitro.
Autorzy:
Levanova AA; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00790 Helsinki, Finland.
Vainio EJ; Natural Resources Institute Finland, 00790 Helsinki, Finland.
Hantula J; Natural Resources Institute Finland, 00790 Helsinki, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00790 Helsinki, Finland.
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Źródło:
Viruses [Viruses] 2021 Aug 31; Vol. 13 (9). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA Viruses/*enzymology
RNA-Dependent RNA Polymerase/*metabolism
Viral Replicase Complex Proteins/*metabolism
Fungal Viruses/genetics ; Fungal Viruses/metabolism ; Genome, Viral ; Nucleotidyltransferases ; RNA Viruses/genetics ; RNA, Double-Stranded ; RNA, Viral ; RNA-Dependent RNA Polymerase/genetics ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structure Unveils Relationships between RNA Virus Polymerases.
Autorzy:
Mönttinen HAM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikki Biocenter 1, P.O. Box 56 (Viikinkaari 9), 00014 Helsinki, Finland.
Ravantti JJ; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikki Biocenter 1, P.O. Box 56 (Viikinkaari 9), 00014 Helsinki, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Viikki Biocenter 1, P.O. Box 56 (Viikinkaari 9), 00014 Helsinki, Finland.
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Źródło:
Viruses [Viruses] 2021 Feb 17; Vol. 13 (2). Date of Electronic Publication: 2021 Feb 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA Viruses/*enzymology
RNA-Dependent RNA Polymerase/*chemistry
Viral Proteins/*chemistry
Models, Molecular ; Phylogeny ; Protein Conformation, alpha-Helical ; Protein Domains ; RNA Viruses/chemistry ; RNA Viruses/classification ; RNA Viruses/genetics ; RNA-Dependent RNA Polymerase/genetics ; RNA-Dependent RNA Polymerase/metabolism ; Viral Proteins/genetics ; Viral Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Herpes Simplex Virus Type 1 Clinical Isolates Respond to UL29-Targeted siRNA Swarm Treatment Independent of Their Acyclovir Sensitivity.
Autorzy:
Kalke K; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Lehtinen J; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Gnjatovic J; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Lund LM; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Nyman MC; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Paavilainen H; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Orpana J; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Lasanen T; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Frejborg F; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Levanova AA; Molecular and Integrative Biosciences Research Programme, Biological and Environmental Sciences, University of Helsinki, 00790 Helsinki, Finland.
Vuorinen T; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.; Clinical Microbiology, Turku University Hospital, 20520 Turku, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Biological and Environmental Sciences, University of Helsinki, 00790 Helsinki, Finland.
Hukkanen V; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
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Źródło:
Viruses [Viruses] 2020 Dec 13; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA Interference*
Acyclovir/*pharmacology
DNA-Binding Proteins/*genetics
Herpes Simplex/*virology
Herpesvirus 1, Human/*drug effects
Herpesvirus 1, Human/*genetics
RNA, Small Interfering/*genetics
Viral Proteins/*genetics
Acyclovir/therapeutic use ; Animals ; Chlorocebus aethiops ; Dose-Response Relationship, Drug ; Drug Resistance, Viral/drug effects ; Drug Resistance, Viral/genetics ; Herpes Simplex/therapy ; Herpesvirus 1, Human/classification ; Herpesvirus 1, Human/isolation & purification ; Humans ; Inhibitory Concentration 50 ; Vero Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural comparison strengthens the higher-order classification of proteases related to chymotrypsin.
Autorzy:
Mönttinen HAM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Ravantti JJ; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.; Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
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Źródło:
PloS one [PLoS One] 2019 May 17; Vol. 14 (5), pp. e0216659. Date of Electronic Publication: 2019 May 17 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chymotrypsin/*classification
Chymotrypsin/*genetics
Chymotrypsin/*ultrastructure
Amino Acid Sequence/genetics ; Binding Sites ; Catalytic Domain ; Peptide Hydrolases/classification ; Peptide Hydrolases/ultrastructure ; Sequence Homology, Amino Acid ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microbial production of lipid-protein vesicles using enveloped bacteriophage phi6.
Autorzy:
Lyytinen OL; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014, Helsinki, Finland.
Starkova D; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014, Helsinki, Finland.; Laboratory of Molecular Epidemiology and Evolutionary Genetics, St. Petersburg Pasteur Institute, Mira St. 14, St. Petersburg, 197101, Russia.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014, Helsinki, Finland. minna.poranen@helsinki.fi.
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Źródło:
Microbial cell factories [Microb Cell Fact] 2019 Feb 07; Vol. 18 (1), pp. 29. Date of Electronic Publication: 2019 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Bacteriophage phi 6/*chemistry
Escherichia coli/*genetics
Viral Matrix Proteins/*genetics
Viral Nonstructural Proteins/*genetics
Cell Membrane ; Phospholipids ; Pseudomonas syringae/chemistry ; Pseudomonas syringae/genetics ; Pseudomonas syringae/virology ; Virion
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Half a Century of Research on Membrane-Containing Bacteriophages: Bringing New Concepts to Modern Virology.
Autorzy:
Mäntynen S; Center of Excellence in Biological Interactions, Department of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, FI-40014 Jyväskylä, Finland. .; Department of Microbiology and Molecular Genetics, University of California, Davis, CA 95616, USA. .
Sundberg LR; Center of Excellence in Biological Interactions, Department of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, FI-40014 Jyväskylä, Finland. .
Oksanen HM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, FI-00014 Helsinki, Finland. .
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, FI-00014 Helsinki, Finland. minna.poranen@helsinki.fi.
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Źródło:
Viruses [Viruses] 2019 Jan 18; Vol. 11 (1). Date of Electronic Publication: 2019 Jan 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Evolution, Molecular*
Bacteriophages/*physiology
Membranes/*metabolism
Archaeal Viruses/genetics ; Bacteriophage PRD1/physiology ; Bacteriophages/genetics ; Capsid Proteins/genetics ; DNA, Viral/genetics ; Models, Molecular ; Virion/metabolism ; Virus Assembly
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Controlled Disassembly and Purification of Functional Viral Subassemblies Using Asymmetrical Flow Field-Flow Fractionation (AF4).
Autorzy:
Eskelin K; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, Viikinkaari 9, University of Helsinki, FI-00014 Helsinki, Finland. .
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, Viikinkaari 9, University of Helsinki, FI-00014 Helsinki, Finland. minna.poranen@helsinki.fi.
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Źródło:
Viruses [Viruses] 2018 Oct 23; Vol. 10 (11). Date of Electronic Publication: 2018 Oct 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fractionation, Field Flow*/methods
Virion/*isolation & purification
Viruses/*isolation & purification
Bacteriophages/genetics ; Bacteriophages/isolation & purification ; Nucleocapsid ; RNA, Double-Stranded ; RNA, Viral ; Viral Proteins ; Virion/genetics ; Viruses/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents.
Autorzy:
Zusinaite E; Institute of Technology, University of Tartu, 50090 Tartu, Estonia. .
Ianevski A; Norwegian University of Science and Technology (NTNU), 7028 Trondheim, Norway. .
Niukkanen D; Institute of Technology, University of Tartu, 50090 Tartu, Estonia. .
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland. minna.poranen@helsinki.fi.
Bjørås M; Norwegian University of Science and Technology (NTNU), 7028 Trondheim, Norway. .; Department of Microbiology, University of Oslo and Oslo University Hospital, 0372 Oslo, Norway. .
Afset JE; Norwegian University of Science and Technology (NTNU), 7028 Trondheim, Norway. .
Tenson T; Institute of Technology, University of Tartu, 50090 Tartu, Estonia. .
Velagapudi V; Institute Molecular Medicine Finland (FIMM), University of Helsinki, 00014 Helsinki, Finland. .
Merits A; Institute of Technology, University of Tartu, 50090 Tartu, Estonia. .
Kainov DE; Institute of Technology, University of Tartu, 50090 Tartu, Estonia. .; Norwegian University of Science and Technology (NTNU), 7028 Trondheim, Norway. .
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Źródło:
Viruses [Viruses] 2018 Aug 12; Vol. 10 (8). Date of Electronic Publication: 2018 Aug 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Antiviral Agents/*adverse effects
Immune System/*drug effects
Nervous System/*drug effects
Systems Biology/*methods
Cytokines/genetics ; Cytokines/immunology ; Epigenomics ; Gene Expression Profiling ; Genomics ; Humans ; Metabolomics ; Precision Medicine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthetic biology approach for plant protection using dsRNA.
Autorzy:
Niehl A; Université de Strasbourg, CNRS, IBMP UPR 2357, Strasbourg, France.
Soininen M; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Heinlein M; Université de Strasbourg, CNRS, IBMP UPR 2357, Strasbourg, France.
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Źródło:
Plant biotechnology journal [Plant Biotechnol J] 2018 Feb 26. Date of Electronic Publication: 2018 Feb 26.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Autorzy:
Collier AM; Department of BioSciences, Rice University, Houston, Texas, United States of America.
Lyytinen OL; Department of Biosciences, University of Helsinki, Helsinki, Finland.
Guo YR; Department of BioSciences, Rice University, Houston, Texas, United States of America.
Toh Y; Department of BioSciences, Rice University, Houston, Texas, United States of America.
Poranen MM; Department of Biosciences, University of Helsinki, Helsinki, Finland.
Tao YJ; Department of BioSciences, Rice University, Houston, Texas, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2016 Apr 14; Vol. 12 (4), pp. e1005523. Date of Electronic Publication: 2016 Apr 14 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Capsid/*metabolism
Genome, Viral/*genetics
RNA Viruses/*genetics
RNA, Double-Stranded/*genetics
RNA, Viral/*metabolism
RNA-Dependent RNA Polymerase/*metabolism
Capsid Proteins/genetics ; Humans ; RNA, Double-Stranded/metabolism ; RNA, Viral/genetics ; Virion/genetics ; Virion/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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