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Tytuł:
The Tumor Microenvironment and Immune Response in Breast Cancer.
Autorzy:
Monzavi-Karbassi B; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Kelly T; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Post SR; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 11; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Editorial
MeSH Terms:
Breast Neoplasms*
Humans ; Female ; Tumor Microenvironment
Opinia redakcyjna
Tytuł:
Echinomycin as a promising therapeutic agent against KSHV-related malignancies.
Autorzy:
Chen J; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR, 72205, USA.
Lin Z; Department of Pathology, Tulane Cancer Center, Tulane University Health Sciences Center, New Orleans, LA, 70112, USA.
Song J; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR, 72205, USA.
Plaisance-Bonstaff K; Department of Medicine, Louisiana Cancer Research Center, Louisiana State University Health Sciences Center, New Orleans, LA, 70112, USA.
James J; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR, 72205, USA.
Mu S; Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Post SR; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR, 72205, USA.
Dai L; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR, 72205, USA. .
Qin Z; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR, 72205, USA. .
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2023 May 04; Vol. 16 (1), pp. 48. Date of Electronic Publication: 2023 May 04.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Herpesvirus 8, Human*/genetics
Echinomycin*/pharmacology
Echinomycin*/therapeutic use
Sarcoma, Kaposi*/drug therapy
Sarcoma, Kaposi*/metabolism
Humans ; Animals ; Mice ; Virus Latency/genetics ; Cell Cycle ; Jumonji Domain-Containing Histone Demethylases
Raport
Tytuł:
Role of Histamine and Related Signaling in Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis and Oncogenesis.
Autorzy:
Chen J; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Song J; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Plaisance-Bonstaff K; Department of Medicine, Louisiana State University Health Sciences Center, Louisiana Cancer Research Center, New Orleans, LA 70112, USA.
Mu S; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Post SR; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Dai L; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Qin Z; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
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Źródło:
Viruses [Viruses] 2023 Apr 20; Vol. 15 (4). Date of Electronic Publication: 2023 Apr 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Herpesvirus 8, Human*/physiology
Sarcoma, Kaposi*
Humans ; Animals ; Mice ; Histamine ; Receptors, Histamine/therapeutic use ; Carcinogenesis ; Cell Transformation, Neoplastic
Czasopismo naukowe
Tytuł:
VT68.2: An Antibody to Chondroitin Sulfate Proteoglycan 4 (CSPG4) Displays Reactivity against a Tumor-Associated Carbohydrate Antigen.
Autorzy:
Nounamo B; Department of Pathology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Jousheghany F; Department of Pathology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Siegel ER; Department of Biostatistics, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Post SR; Department of Pathology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.; Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Kelly T; Department of Pathology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.; Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Ferrone S; Department of Surgery, Massachusetts General Hospital, Yaw 7, 55 Fruit St, Boston, MA 02114, USA.
Kieber-Emmons T; Department of Pathology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.; Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Monzavi-Karbassi B; Department of Pathology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.; Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 28; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Proteoglycans*
Triple Negative Breast Neoplasms*
Humans ; Chondroitin Sulfate Proteoglycans/metabolism ; Antibodies, Monoclonal/pharmacology ; Antigens, Tumor-Associated, Carbohydrate ; Membrane Proteins
Czasopismo naukowe
Tytuł:
SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus.
Autorzy:
Chen J; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Dai L; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Barrett L; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
James J; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Plaisance-Bonstaff K; Department of Medicine, Louisiana State University Health Sciences Center, Louisiana Cancer Research Center, New Orleans, LA, USA.
Post SR; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Qin Z; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA. .
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Źródło:
Communications biology [Commun Biol] 2021 Jun 03; Vol. 4 (1), pp. 682. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Virus Activation*/drug effects
Antiviral Agents/*pharmacology
COVID-19/*complications
Herpesvirus 8, Human/*physiology
SARS-CoV-2/*physiology
Sarcoma, Kaposi/*etiology
Azithromycin/pharmacology ; Benzamidines/pharmacology ; Cell Line ; Guanidines/pharmacology ; Herpesviridae Infections/chemically induced ; Herpesviridae Infections/etiology ; Herpesvirus 8, Human/drug effects ; Humans ; Oncogenic Viruses/drug effects ; Oncogenic Viruses/physiology ; SARS-CoV-2/drug effects ; Sarcoma, Kaposi/chemically induced ; Viral Proteins/metabolism ; COVID-19 Drug Treatment
Czasopismo naukowe
Tytuł:
Identification of new antiviral agents against Kaposi's sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation.
Autorzy:
Chen J; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Dai L; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Goldstein A; Departments of Diagnostic Sciences, School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America.
Zhang H; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Hubei, China.
Tang W; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Hubei, China.
Forrest JC; Department of Microbiology & Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Post SR; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Chen X; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Hubei, China.; Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China.
Qin Z; Department of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2019 Dec 02; Vol. 15 (12), pp. e1008156. Date of Electronic Publication: 2019 Dec 02 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents/*pharmacology
Herpesvirus 8, Human/*drug effects
Histamine/*metabolism
Sarcoma, Kaposi/*virology
Virus Activation/*drug effects
Drug Evaluation, Preclinical ; Herpesvirus 8, Human/physiology ; High-Throughput Screening Assays ; Humans ; Receptors, Histamine/metabolism ; Signal Transduction/physiology ; Virus Activation/physiology ; Virus Latency/drug effects ; Virus Latency/physiology
Czasopismo naukowe
Tytuł:
Identification of a novel monocytic phenotype in Classic Hodgkin Lymphoma tumor microenvironment.
Autorzy:
Post GR; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Yuan Y; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Holthoff ER; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Quick CM; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Post SR; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
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Źródło:
PloS one [PLoS One] 2019 Nov 12; Vol. 14 (11), pp. e0224621. Date of Electronic Publication: 2019 Nov 12 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD/*metabolism
Hodgkin Disease/*pathology
Monocytes/*pathology
Tumor Microenvironment/*physiology
Hodgkin Disease/metabolism ; Humans ; Macrophages/metabolism ; Macrophages/pathology ; Monocytes/metabolism ; Phenotype ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1.
Autorzy:
Holthoff ER; Department of Pathology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Slot 845, Little Rock, AR 72205 USA.
Byrum SD; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Slot 845, Little Rock, AR 72205 USA.
Mackintosh SG; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Slot 845, Little Rock, AR 72205 USA.
Kelly T; Department of Pathology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Slot 845, Little Rock, AR 72205 USA.
Tackett AJ; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Slot 845, Little Rock, AR 72205 USA.
Quick CM; Department of Pathology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Slot 845, Little Rock, AR 72205 USA.
Post SR; Department of Pathology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Slot 845, Little Rock, AR 72205 USA.
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Źródło:
Clinical proteomics [Clin Proteomics] 2017 Dec 06; Vol. 14, pp. 40. Date of Electronic Publication: 2017 Dec 06 (Print Publication: 2017).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Cleavage of Type I Collagen by Fibroblast Activation Protein-α Enhances Class A Scavenger Receptor Mediated Macrophage Adhesion.
Autorzy:
Mazur A; Interdisciplinary Biomedical Sciences Program, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Holthoff E; Interdisciplinary Biomedical Sciences Program, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Vadali S; Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Kelly T; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Post SR; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
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Źródło:
PloS one [PLoS One] 2016 Mar 02; Vol. 11 (3), pp. e0150287. Date of Electronic Publication: 2016 Mar 02 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Collagen Type I/*metabolism
Gelatinases/*metabolism
Macrophages/*cytology
Membrane Proteins/*metabolism
Scavenger Receptors, Class A/*metabolism
Serine Endopeptidases/*metabolism
Animals ; Breast/metabolism ; Breast/pathology ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Adhesion ; Cells, Cultured ; Endopeptidases ; Female ; Humans ; Integrins/metabolism ; Macrophages/metabolism ; Macrophages/pathology ; Mice, Inbred C57BL ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł:
The ral exchange factor rgl2 promotes cardiomyocyte survival and inhibits cardiac fibrosis.
Autorzy:
Scotland RL; Department of Molecular and Biomedical Pharmacology, University of Kentucky, Lexington, Kentucky, United States of America.
Allen L
Hennings LJ
Post GR
Post SR
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Źródło:
PloS one [PLoS One] 2013 Sep 17; Vol. 8 (9), pp. e73599. Date of Electronic Publication: 2013 Sep 17 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Myocytes, Cardiac/*cytology
Myocytes, Cardiac/*metabolism
Transcription Factors/*metabolism
Animals ; Cell Survival/genetics ; Cell Survival/physiology ; Cells, Cultured ; Guanine Nucleotide Exchange Factors ; Humans ; Male ; Mice ; Mice, Transgenic ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł:
Prolonged prothrombin time correlates with serum monoclonal protein concentration in patients with plasma cell dyscrasia.
Autorzy:
Pandey S; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Post SR
Alapat DV
Smock KJ
Post GR
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Źródło:
International journal of laboratory hematology [Int J Lab Hematol] 2013 Aug; Vol. 35 (4), pp. 421-7. Date of Electronic Publication: 2012 Dec 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Partial Thromboplastin Time*
Prothrombin Time*
Glycoproteins/*blood
Multiple Myeloma/*blood
Paraproteinemias/*blood
Aged ; Blood Coagulation ; Female ; Fibrinogen/metabolism ; Humans ; Male ; Middle Aged ; Multiple Myeloma/diagnosis ; Paraproteinemias/diagnosis ; Reference Values ; Severity of Illness Index
Czasopismo naukowe
Tytuł:
SR-A ligand and M-CSF dynamically regulate SR-A expression and function in primary macrophages via p38 MAPK activation.
Autorzy:
Nikolic D; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.
Calderon L
Du L
Post SR
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Źródło:
BMC immunology [BMC Immunol] 2011 Jul 07; Vol. 12, pp. 37. Date of Electronic Publication: 2011 Jul 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Macrophage Colony-Stimulating Factor/*metabolism
Macrophages/*immunology
Scavenger Receptors, Class A/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Animals ; Gene Expression Regulation/drug effects ; Immunologic Factors/metabolism ; Immunologic Factors/pharmacology ; Lipoproteins, LDL/metabolism ; Macrophage Colony-Stimulating Factor/pharmacology ; Macrophages/enzymology ; Macrophages/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Protein Biosynthesis/drug effects ; RNA, Messenger/genetics ; Scavenger Receptors, Class A/genetics ; Up-Regulation/drug effects
Czasopismo naukowe

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