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Wyszukujesz frazę ""Potassium Channels, Inwardly Rectifying"" wg kryterium: Temat


Tytuł :
Successful transition from insulin to sulfonylurea, on second attempt, in a 24-year-old female with neonatal diabetes secondary to KCNJ11 gene mutation.
Autorzy :
Hajji S; Endocrinology, Mater Misericordiae University Hospital, Dublin, Ireland .
Aljenaee K; Endocrine and Diabetes, Saint James's Hospital, Dublin, Ireland.
Garrahy A; Endocrinology and Diabetes, South Infirmary Victoria University Hospital, Cork, Ireland.
Byrne M; Endocrinology, Mater Misericordiae University Hospital, Dublin, Ireland.
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Źródło :
BMJ case reports [BMJ Case Rep] 2021 Apr 09; Vol. 14 (4). Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Diabetes Mellitus*/drug therapy
Diabetes Mellitus*/genetics
Potassium Channels, Inwardly Rectifying*/genetics
Adolescent ; Adult ; Female ; Humans ; Hypoglycemic Agents/therapeutic use ; Infant ; Infant, Newborn ; Insulin ; Mutation ; Quality of Life ; Sulfonylurea Compounds/therapeutic use ; Young Adult
Czasopismo naukowe
Tytuł :
Flonicamid and knockdown of inward rectifier potassium channel gene CsKir2B adversely affect the feeding and development of Chilo suppressalis.
Autorzy :
Meng X; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Wu Z; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Yang X; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Qian K; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Zhang N; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Jiang H; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Yin X; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Guan D; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Zheng Y; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.
Wang J; College of Horticulture and Plant Protection, Yangzhou University, Yangzhou, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education, Yangzhou University, Yangzhou, China.
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Źródło :
Pest management science [Pest Manag Sci] 2021 Apr; Vol. 77 (4), pp. 2045-2053. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article
MeSH Terms :
Moths*/genetics
Potassium Channels, Inwardly Rectifying*/genetics
Animals ; Larva/genetics ; Niacinamide/analogs & derivatives
Czasopismo naukowe
Tytuł :
Focal congenital hyperinsulinism resulting from biallelic loss of function of KCNJ11 gene.
Autorzy :
Garegrat R; Department of Neonatology, Bharati Hospital and Research Centre, Pune, Maharashtra, India .
Patnaik S; Department of Neonatology, Bharati Hospital and Research Centre, Pune, Maharashtra, India.
Suryawanshi P; Neonatology, Bharati Vidyapeeth University, Pune, Maharashtra, India.
Datar C; Department of Neonatology, Bharati Hospital and Research Centre, Pune, Maharashtra, India.
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Źródło :
BMJ case reports [BMJ Case Rep] 2021 Mar 24; Vol. 14 (3). Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Congenital Hyperinsulinism*/genetics
Congenital Hyperinsulinism*/surgery
Hyperinsulinism*/genetics
Potassium Channels, Inwardly Rectifying*/genetics
Humans ; Mutation ; Octreotide/therapeutic use ; Sulfonylurea Receptors/genetics
Czasopismo naukowe
Tytuł :
Correlation between Kir4.1 expression and barium-sensitive currents in rat and human glioma cell lines.
Autorzy :
Madadi A; Oscar Langendorff Institute of Physiology, Rostock University Medical Center, Rostock, Germany.
Wolfart J; Oscar Langendorff Institute of Physiology, Rostock University Medical Center, Rostock, Germany.
Lange F; Oscar Langendorff Institute of Physiology, Rostock University Medical Center, Rostock, Germany; Center of Transdisciplinary Neurosciences Rostock, (CTNR), Rostock University Medical Center, Germany.
Brehme H; Department of Neurology, Rostock University Medical Center, Germany.
Linnebacher M; Department of General Surgery, Rostock University Medical Center, Germany.
Bräuer AU; Research Group Anatomy, School for Medicine and Health Science, Carl von Ossietzky University Oldenburg, Oldenburg, Germany; Research Center for Neurosensory Science, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.
Büttner A; Institute of Forensic Medicine, Rostock University Medical Center, Germany.
Freiman T; Department of Neurosurgery, Rostock University Medical Center, Germany.
Henker C; Department of Neurosurgery, Rostock University Medical Center, Germany.
Einsle A; Oscar Langendorff Institute of Physiology, Rostock University Medical Center, Rostock, Germany.
Rackow S; Oscar Langendorff Institute of Physiology, Rostock University Medical Center, Rostock, Germany.
Köhling R; Oscar Langendorff Institute of Physiology, Rostock University Medical Center, Rostock, Germany; Center of Transdisciplinary Neurosciences Rostock, (CTNR), Rostock University Medical Center, Germany.
Kirschstein T; Oscar Langendorff Institute of Physiology, Rostock University Medical Center, Rostock, Germany; Center of Transdisciplinary Neurosciences Rostock, (CTNR), Rostock University Medical Center, Germany.
Müller S; Oscar Langendorff Institute of Physiology, Rostock University Medical Center, Rostock, Germany. Electronic address: .
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Źródło :
Neuroscience letters [Neurosci Lett] 2021 Jan 10; Vol. 741, pp. 135481. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Barium/*administration & dosage
Brain Neoplasms/*physiopathology
Glioma/*physiopathology
Potassium Channels, Inwardly Rectifying/*physiology
Animals ; Brain Neoplasms/metabolism ; Cell Line, Tumor ; Glioma/metabolism ; Hippocampus/drug effects ; Hippocampus/physiopathology ; Humans ; Membrane Potentials/drug effects ; Potassium Channels, Inwardly Rectifying/metabolism ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Long noncoding RNA TCONS-00106987 promotes atrial electrical remodelling during atrial fibrillation by sponging miR-26 to regulate KCNJ2.
Autorzy :
Du J; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Li Z; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Wang X; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Li J; Department of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Liu D; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Wang X; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Wei J; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Ma S; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Zhang Y; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Hou Y; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Nov; Vol. 24 (21), pp. 12777-12788. Date of Electronic Publication: 2020 Sep 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Atrial Fibrillation/*genetics
Atrial Fibrillation/*physiopathology
Atrial Remodeling/*genetics
MicroRNAs/*metabolism
Potassium Channels, Inwardly Rectifying/*genetics
RNA, Long Noncoding/*metabolism
Animals ; Base Sequence ; Binding, Competitive ; Female ; Gene Expression Profiling ; Male ; MicroRNAs/genetics ; Potassium Channels, Inwardly Rectifying/metabolism ; RNA, Long Noncoding/genetics ; Rabbits ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Modulation of Actin Filament Dynamics by Inward Rectifying of Potassium Channel Kir2.1.
Autorzy :
Wu L; Molecular Pharmacology Laboratory, Institute of Molecular Medicine, Peking University, Beijing 100871, China.; Aston Medical School, Aston University, Birmingham B4 7ET, UK.
Wang Q; Department of Biopharmaceutics, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Gu J; Molecular Pharmacology Laboratory, Institute of Molecular Medicine, Peking University, Beijing 100871, China.
Zhang H; Molecular Pharmacology Laboratory, Institute of Molecular Medicine, Peking University, Beijing 100871, China.
Gu Y; Molecular Pharmacology Laboratory, Institute of Molecular Medicine, Peking University, Beijing 100871, China.; Aston Medical School, Aston University, Birmingham B4 7ET, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 10; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article
MeSH Terms :
Ion Channel Gating*
Actin Cytoskeleton/*metabolism
Actins/*metabolism
Potassium Channels, Inwardly Rectifying/*metabolism
Aquaporins/metabolism ; Cell Adhesion/genetics ; Cell Line ; Cell Membrane/metabolism ; Cell Movement/genetics ; Fluorescent Antibody Technique ; Gene Expression ; Humans ; Phosphorylation ; Potassium Channels, Inwardly Rectifying/genetics ; Protein Binding
Czasopismo naukowe
Tytuł :
Oscillating shear stress mediates mesenchymal transdifferentiation of EPCs by the Kir2.1 channel.
Autorzy :
Li J; School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
He Y; School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Bu H; Department of Gynaecology and Obstetrics, The 89 Hospital of Chinese PLA, Weifang, 261021, Shandong, People's Republic of China.
Wang M; School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Yu J; School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Li L; School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Li H; School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Zhang X; School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Cui X; School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China. .
Cheng M; School of Basic Medical Sciences, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China. .
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Źródło :
Heart and vessels [Heart Vessels] 2020 Oct; Vol. 35 (10), pp. 1473-1482. Date of Electronic Publication: 2020 May 24.
Typ publikacji :
Journal Article
MeSH Terms :
Epithelial-Mesenchymal Transition*
Mechanotransduction, Cellular*
Vascular Remodeling*
Carotid Artery Injuries/*metabolism
Endothelial Progenitor Cells/*metabolism
Potassium Channels, Inwardly Rectifying/*metabolism
Animals ; Carotid Artery Injuries/genetics ; Carotid Artery Injuries/pathology ; Cells, Cultured ; Disease Models, Animal ; Endothelial Progenitor Cells/pathology ; Endothelial Progenitor Cells/transplantation ; Neovascularization, Physiologic ; Potassium Channels, Inwardly Rectifying/genetics ; Rats, Sprague-Dawley ; Stress, Mechanical
Czasopismo naukowe
Tytuł :
Kir4.1 RNA Interference by In Utero Electroporation Fails to Affect Ictogenesis and Reveals a Possible role of Kir4.1 in Corticogenesis.
Autorzy :
Moroni RF; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
Regondi MC; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
de Curtis M; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
Frassoni C; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
Librizzi L; Epilepsy Unit, Fondazione I.R.C.C.S. Istituto Neurologico 'C. Besta', via Celoria 11, 20133 Milan, Italy. Electronic address: .
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Źródło :
Neuroscience [Neuroscience] 2020 Aug 10; Vol. 441, pp. 65-76. Date of Electronic Publication: 2020 Jun 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Potassium Channels, Inwardly Rectifying*/genetics
Potassium Channels, Inwardly Rectifying*/metabolism
Animals ; Astrocytes/metabolism ; Electroporation ; Potassium/metabolism ; RNA Interference ; Rats
Czasopismo naukowe
Tytuł :
The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K -mediated neurovascular communication.
Autorzy :
Moshkforoush A; Department of Biomedical Engineering, Florida International University, Miami, FL 33199.
Ashenagar B; Department of Biomedical Engineering, Florida International University, Miami, FL 33199.
Harraz OF; Department of Pharmacology, College of Medicine, University of Vermont, Burlington, VT 05405.
Dabertrand F; Department of Pharmacology, College of Medicine, University of Vermont, Burlington, VT 05405.; Department of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Longden TA; Department of Pharmacology, College of Medicine, University of Vermont, Burlington, VT 05405.; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201.
Nelson MT; Department of Pharmacology, College of Medicine, University of Vermont, Burlington, VT 05405.; Division of Cardiovascular Sciences, University of Manchester, Manchester M13 9PL, United Kingdom.
Tsoukias NM; Department of Biomedical Engineering, Florida International University, Miami, FL 33199; .; School of Chemical Engineering, National Technical University of Athens, Zografou 157 72, Greece.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 14; Vol. 117 (28), pp. 16626-16637. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurovascular Coupling*
Neurons/*metabolism
Potassium/*metabolism
Potassium Channels, Inwardly Rectifying/*metabolism
Animals ; Brain/blood supply ; Brain/metabolism ; Cerebrovascular Circulation ; Endothelial Cells/chemistry ; Endothelial Cells/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Models, Biological ; Neurons/chemistry ; Potassium/chemistry ; Potassium Channels, Inwardly Rectifying/chemistry ; Potassium Channels, Inwardly Rectifying/genetics ; Signal Transduction ; TRPV Cation Channels/chemistry ; TRPV Cation Channels/genetics ; TRPV Cation Channels/metabolism
Czasopismo naukowe
Tytuł :
Electromechanical coupling in the hyperpolarization-activated K channel KAT1.
Autorzy :
Clark MD; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.
Contreras GF; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.
Shen R; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.
Perozo E; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA. .
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Źródło :
Nature [Nature] 2020 Jul; Vol. 583 (7814), pp. 145-149. Date of Electronic Publication: 2020 May 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Arabidopsis*/chemistry
Arabidopsis*/ultrastructure
Cryoelectron Microscopy*
Ion Channel Gating*
Arabidopsis Proteins/*chemistry
Arabidopsis Proteins/*metabolism
Potassium Channels, Inwardly Rectifying/*chemistry
Potassium Channels, Inwardly Rectifying/*metabolism
Allosteric Regulation ; Arabidopsis Proteins/ultrastructure ; Binding Sites ; Lipids ; Models, Molecular ; Potassium Channels, Inwardly Rectifying/ultrastructure ; Protein Conformation
Czasopismo naukowe
Tytuł :
KCNJ15 Expression and Malignant Behavior of Esophageal Squamous Cell Carcinoma.
Autorzy :
Nakamura S; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kanda M; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan. .
Koike M; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shimizu D; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
Umeda S; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hattori N; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hayashi M; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
Tanaka C; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kobayashi D; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yamada S; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
Omae K; Department of Innovative Research and Education for Clinicians and Trainees (DiRECT), Fukushima Medical University Hospital, Fukushima City, Fukushima, Japan.
Kodera Y; Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.
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Źródło :
Annals of surgical oncology [Ann Surg Oncol] 2020 Jul; Vol. 27 (7), pp. 2559-2568. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji :
Journal Article
MeSH Terms :
Esophageal Neoplasms*/genetics
Esophageal Neoplasms*/metabolism
Esophageal Neoplasms*/pathology
Esophageal Squamous Cell Carcinoma*/genetics
Esophageal Squamous Cell Carcinoma*/metabolism
Esophageal Squamous Cell Carcinoma*/pathology
Potassium Channels, Inwardly Rectifying*/biosynthesis
Potassium Channels, Inwardly Rectifying*/genetics
Biomarkers, Tumor/genetics ; Cell Line, Tumor ; Cell Movement/physiology ; Cell Proliferation/physiology ; Humans ; Prognosis
Czasopismo naukowe
Tytuł :
Late-Onset Bartter Syndrome Type II Due to a Homozygous Mutation in KCNJ1 Gene: A Case Report and Literature Review.
Autorzy :
Elfert KA; Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar.
Geller DS; Department of Nephrology, Yale University School of Medicine, New Haven, CT, USA.; Department of Nephrology, West Haven VA Hospital, West Haven, CT, USA.
Nelson-Williams C; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Lifton RP; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Al-Malki H; Department of Nephrology, Hamad Medical Corporation, Doha, Qatar.
Nauman A; Department of Nephrology, Hamad Medical Corporation, Doha, Qatar.
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Źródło :
The American journal of case reports [Am J Case Rep] 2020 Sep 30; Vol. 21, pp. e924527. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Bartter Syndrome*/diagnosis
Bartter Syndrome*/genetics
Hypokalemia*/genetics
Potassium Channels, Inwardly Rectifying*/genetics
Adult ; Female ; Homozygote ; Humans ; Male ; Mutation ; Mutation, Missense ; Pregnancy
Czasopismo naukowe
Tytuł :
Impairment of Flow-Sensitive Inwardly Rectifying K Channels via Disruption of Glycocalyx Mediates Obesity-Induced Endothelial Dysfunction.
Autorzy :
Fancher IS; From the Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine (I.S.F., E.L.M., S.J.A., C.A., I.L.), University of Illinois at Chicago.
Le Master E; From the Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine (I.S.F., E.L.M., S.J.A., C.A., I.L.), University of Illinois at Chicago.
Ahn SJ; From the Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine (I.S.F., E.L.M., S.J.A., C.A., I.L.), University of Illinois at Chicago.
Adamos C; From the Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine (I.S.F., E.L.M., S.J.A., C.A., I.L.), University of Illinois at Chicago.
Lee JC; Departement of Bioengineering (J.C.L.), University of Illinois at Chicago.
Berdyshev E; Division of Pulmonary, Critical Care and Sleep Medicine, Departement of Medicine, National Jewish Health, Denver, CO (E.B.).
Dull RO; Department of Anesthesiology, University of Arizona College of Medicine, Banner-University Medical Center, Tucson (R.O.D.).
Phillips SA; Department of Physical Therapy (S.A.P.), University of Illinois at Chicago.
Levitan I; From the Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine (I.S.F., E.L.M., S.J.A., C.A., I.L.), University of Illinois at Chicago.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Sep; Vol. 40 (9), pp. e240-e255. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Vasodilation*
Endothelial Cells/*metabolism
Endothelium, Vascular/*metabolism
Glycocalyx/*metabolism
Mesenteric Arteries/*metabolism
Obesity/*metabolism
Potassium Channels, Inwardly Rectifying/*metabolism
Adult ; Animals ; Cells, Cultured ; Diet, High-Fat ; Disease Models, Animal ; Endothelium, Vascular/physiopathology ; Female ; Heparitin Sulfate/metabolism ; Humans ; Male ; Mechanotransduction, Cellular ; Membrane Potentials ; Mesenteric Arteries/physiopathology ; Mice ; Middle Aged ; Obesity/genetics ; Obesity/physiopathology ; Potassium Channels, Inwardly Rectifying/genetics ; Regional Blood Flow
Czasopismo naukowe
Tytuł :
Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents.
Autorzy :
Park SS; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Ponce-Balbuena D; Department of Internal Medicine and Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
Kuick R; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Guerrero-Serna G; Department of Internal Medicine and Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.
Yoon J; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Mellacheruvu D; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Conlon KP; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Basrur V; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Nesvizhskii AI; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.
Jalife J; Department of Internal Medicine and Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA .; Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, Spain.
Rual JF; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA .
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Źródło :
Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2020 Sep; Vol. 19 (9), pp. 1436-1449. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Protein Interaction Maps*/genetics
Protein Interaction Maps*/physiology
Andersen Syndrome/*metabolism
Myocytes, Cardiac/*metabolism
Plakophilins/*metabolism
Potassium/*metabolism
Potassium Channels, Inwardly Rectifying/*metabolism
Action Potentials/drug effects ; Action Potentials/physiology ; Andersen Syndrome/genetics ; Andersen Syndrome/physiopathology ; Chromatography, Liquid ; Desmosomes/drug effects ; Desmosomes/metabolism ; HEK293 Cells ; Humans ; Lysosomes/metabolism ; Molecular Chaperones/metabolism ; Mutation ; Myocytes, Cardiac/drug effects ; Patch-Clamp Techniques ; Potassium Channels, Inwardly Rectifying/genetics ; Protein Transport/genetics ; Protein Transport/physiology ; Signal Transduction/genetics ; Signal Transduction/physiology ; Somatomedins/metabolism ; Tandem Mass Spectrometry ; Utrophin/metabolism
Czasopismo naukowe
Tytuł :
A Soluble Epoxide Hydrolase Inhibitor Upregulated KCNJ12 and KCNIP2 by Downregulating MicroRNA-29 in a Mouse Model of Myocardial Infarction.
Autorzy :
Zhang X; Department of Internal Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha. .
Liao C; Department of Geratology, The Third Hospital of Changsha, Changsha, Hunan, China. .
Sun K; Department of Internal Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha. .
Liu L; Department of Internal Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha. .
Xu D; Department of Internal Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha. .
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Źródło :
The heart surgery forum [Heart Surg Forum] 2020 Aug 12; Vol. 23 (5), pp. E579-E585. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Kv Channel-Interacting Proteins/*genetics
MicroRNAs/*genetics
Myocardial Infarction/*genetics
Myocardium/*metabolism
Potassium Channels, Inwardly Rectifying/*genetics
Animals ; Blotting, Western ; Disease Models, Animal ; Down-Regulation ; Kv Channel-Interacting Proteins/biosynthesis ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/biosynthesis ; Myocardial Infarction/metabolism ; Myocardial Infarction/pathology ; Myocardium/pathology ; Potassium Channels, Inwardly Rectifying/biosynthesis ; RNA/genetics ; RNA/metabolism
Czasopismo naukowe
Tytuł :
Towards the Development of AgoKirs: New Pharmacological Activators to Study K ir 2.x Channel and Target Cardiac Disease.
Autorzy :
van der Schoor L; Honours Program CRU+ Bachelor, University Medical Center Utrecht, Heidelberglaan 100, 3584 CM Utrecht, The Netherlands.
van Hattum EJ; Honours Program CRU+ Bachelor, University Medical Center Utrecht, Heidelberglaan 100, 3584 CM Utrecht, The Netherlands.
de Wilde SM; Honours Program CRU+ Bachelor, University Medical Center Utrecht, Heidelberglaan 100, 3584 CM Utrecht, The Netherlands.
Harlianto NI; Honours Program CRU+ Bachelor, University Medical Center Utrecht, Heidelberglaan 100, 3584 CM Utrecht, The Netherlands.
van Weert AJ; Honours Program CRU+ Bachelor, University Medical Center Utrecht, Heidelberglaan 100, 3584 CM Utrecht, The Netherlands.
Bloothooft M; Department of Medical Physiology, Division of Heart & Lungs, University Medical Center Utrecht, Yalelaan 50, 3584 CM Utrecht, The Netherlands.
van der Heyden MAG; Department of Medical Physiology, Division of Heart & Lungs, University Medical Center Utrecht, Yalelaan 50, 3584 CM Utrecht, The Netherlands.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 11; Vol. 21 (16). Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heart Diseases/*drug therapy
Potassium Channels, Inwardly Rectifying/*agonists
Animals ; Humans ; Ion Channel Gating ; Potassium Channels, Inwardly Rectifying/chemistry
Czasopismo naukowe
Tytuł :
Cardiac Arrest Risk During Acute Infections: Systemic Inflammation Directly Prolongs QTc Interval via Cytokine-Mediated Effects on Potassium Channel Expression.
Autorzy :
Lazzerini PE; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
Acampa M; Stroke Unit (M.A.), University Hospital of Siena, Italy.
Laghi-Pasini F; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
Bertolozzi I; Cardiology Intensive Therapy Unit, Department of Internal Medicine, Hospital of Carrara, Italy (I.B.).
Finizola F; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
Vanni F; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
Natale M; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
Bisogno S; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
Cevenini G; Department of Medical Biotechnologies (G.C., A.C.), University Hospital of Siena, Italy.
Cartocci A; Department of Medical Biotechnologies (G.C., A.C.), University Hospital of Siena, Italy.
Giabbani B; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
Migliacci N; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
D'Errico A; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
Dokollari A; Department of Cardiac Surgery (A. Dokollari, M.M.), University Hospital of Siena, Italy.; Department of Cardiovascular Surgery, Saint Michael Hospital, University of Toronto, Ontario, Canada (A. Dokollari).
Maccherini M; Department of Cardiac Surgery (A. Dokollari, M.M.), University Hospital of Siena, Italy.; VA New York Harbor Healthcare System, SUNY Downstate Medical Center (M.B.).; NYU School of Medicine (M.B.).
Boutjdir M
Capecchi PL; Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., F.F., F.V., M.N., S.B., B.G., N.M., A. D'Errico, P.L.C.), University Hospital of Siena, Italy.
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Źródło :
Circulation. Arrhythmia and electrophysiology [Circ Arrhythm Electrophysiol] 2020 Aug; Vol. 13 (8), pp. e008627. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heart Rate*/drug effects
Communicable Diseases/*metabolism
Cytokines/*metabolism
Heart Arrest/*metabolism
Heart Ventricles/*metabolism
Inflammation/*metabolism
Leukocytes, Mononuclear/*metabolism
Potassium Channels, Inwardly Rectifying/*metabolism
Torsades de Pointes/*metabolism
Action Potentials ; Acute Disease ; Adult ; Aged ; Aged, 80 and over ; Anti-Infective Agents/adverse effects ; Communicable Diseases/drug therapy ; Communicable Diseases/epidemiology ; Communicable Diseases/physiopathology ; Female ; Heart Arrest/epidemiology ; Heart Arrest/physiopathology ; Heart Ventricles/drug effects ; Heart Ventricles/physiopathology ; Humans ; Inflammation/epidemiology ; Inflammation/physiopathology ; Leukocytes, Mononuclear/drug effects ; Male ; Middle Aged ; Potassium Channels, Inwardly Rectifying/genetics ; Prevalence ; Risk Factors ; Signal Transduction ; Time Factors ; Torsades de Pointes/epidemiology ; Torsades de Pointes/physiopathology ; Young Adult
Czasopismo naukowe
Tytuł :
Structural Determinants of Insulin Release: Disordered N-Terminal Tail of Kir6.2 Affects Potassium Channel Dynamics through Interactions with Sulfonylurea Binding Region in a SUR1 Partner.
Autorzy :
Walczewska-Szewc K; Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Grudziądzka 5, 87-100 Toruń, Poland.; Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University, Wileńska 4, 87-100 Toruń, Poland.
Nowak W; Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Grudziądzka 5, 87-100 Toruń, Poland.
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Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2020 Jul 23; Vol. 124 (29), pp. 6198-6211. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Potassium Channels, Inwardly Rectifying*/genetics
Adenosine Triphosphate ; Insulin/genetics ; Molecular Docking Simulation ; Sulfonylurea Receptors/genetics
Czasopismo naukowe
Tytuł :
Magnesium Deficiency Causes Transcriptional Downregulation of Kir2.1 and Kv4.2 Channels in Cardiomyocytes Resulting in QT Interval Prolongation.
Autorzy :
Shimaoka T; Department of Pathophysiology, Oita University School of Medicine.; Department of Cardiovascular Surgery, Oita University School of Medicine.
Wang Y; Department of Pathophysiology, Oita University School of Medicine.
Morishima M; Department of Pathophysiology, Oita University School of Medicine.
Miyamoto S; Department of Cardiovascular Surgery, Oita University School of Medicine.
Ono K; Department of Pathophysiology, Oita University School of Medicine.
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Źródło :
Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2020 Jul 22; Vol. 84 (8), pp. 1244-1253. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Action Potentials*
Heart Rate*
Arrhythmias, Cardiac/*etiology
Magnesium Deficiency/*complications
Myocytes, Cardiac/*metabolism
Potassium Channels, Inwardly Rectifying/*metabolism
Shal Potassium Channels/*metabolism
Animals ; Arrhythmias, Cardiac/genetics ; Arrhythmias, Cardiac/metabolism ; Arrhythmias, Cardiac/physiopathology ; Disease Models, Animal ; Down-Regulation ; Male ; Potassium Channels, Inwardly Rectifying/genetics ; Rats, Wistar ; Shal Potassium Channels/genetics ; Signal Transduction ; Time Factors ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Cell-type-independent expression of inwardly rectifying potassium currents in mouse fungiform taste bud cells.
Autorzy :
Nakao Y; Department of Human Intelligence Systems, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Kitakyushu, Japan. .
Koshimura M
Yamasaki T
Ohtubo Y
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Źródło :
Physiological research [Physiol Res] 2020 Jul 16; Vol. 69 (3), pp. 501-510. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Epithelium/*metabolism
Patch-Clamp Techniques/*methods
Potassium/*metabolism
Potassium Channels, Inwardly Rectifying/*metabolism
Taste Buds/*metabolism
Action Potentials ; Animals ; Membrane Potentials ; Mice ; Potassium Channels, Inwardly Rectifying/genetics ; RNA, Messenger/genetics
Czasopismo naukowe

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