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Wyszukujesz frazę ""Potassium Channels, Inwardly Rectifying"" wg kryterium: Temat

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Wyświetlanie 1-20 z 41
Tytuł:
Real-time RT-PCR threshold cycles value for Kir6.1 from the blood correlates with parameters of vascular function: a potential for the vascular function biomarker?
Autorzy:
Khan F; Medical Research Institute, Division of Cardiovascular and Diabetic Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, UK.
Choong WL
Du Q
Jovanović A
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Źródło:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2013 May; Vol. 18 (3), pp. 221-9. Date of Electronic Publication: 2013 Mar 13.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression*
ATP-Binding Cassette Transporters/*blood
Brachial Artery/*metabolism
Hyperemia/*blood
KATP Channels/*blood
Potassium Channels, Inwardly Rectifying/*blood
Receptors, Drug/*blood
ATP-Binding Cassette Transporters/genetics ; Biomarkers/blood ; Dilatation ; Female ; Humans ; Hyperemia/genetics ; KATP Channels/genetics ; Male ; Microcirculation ; Potassium Channels, Inwardly Rectifying/genetics ; Protein Isoforms/blood ; Protein Isoforms/genetics ; Real-Time Polymerase Chain Reaction/standards ; Receptors, Drug/genetics ; Sex Factors ; Sulfonylurea Receptors ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles.
Autorzy:
Fotinou C; Department of Physiology, Henry Wellcome Centre for Gene Function, University of Oxford, Oxford, UK.
Aittoniemi J
de Wet H
Polidori A
Pucci B
Sansom MS
Vénien-Bryan C
Ashcroft FM
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Źródło:
The FEBS journal [FEBS J] 2013 Feb; Vol. 280 (4), pp. 1051-63. Date of Electronic Publication: 2013 Jan 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP-Binding Cassette Transporters/*ultrastructure
Potassium Channels, Inwardly Rectifying/*ultrastructure
Receptors, Drug/*ultrastructure
ATP-Binding Cassette Transporters/chemistry ; Animals ; Models, Molecular ; Potassium Channels, Inwardly Rectifying/chemistry ; Protein Multimerization ; Protein Structure, Quaternary ; Protein Structure, Tertiary ; Protein Subunits/chemistry ; Rats ; Receptors, Drug/chemistry ; Sf9 Cells ; Structural Homology, Protein ; Sulfonylurea Receptors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Does inhibiting Sur1 complement rt-PA in cerebral ischemia?
Autorzy:
Simard JM; Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, USA. />Geng Z
Silver FL
Sheth KN
Kimberly WT
Stern BJ
Colucci M
Gerzanich V
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Źródło:
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2012 Sep; Vol. 1268, pp. 95-107.
Typ publikacji:
Journal Article; Review
MeSH Terms:
ATP-Binding Cassette Transporters/*antagonists & inhibitors
Antioxidants/*pharmacology
Brain Ischemia/*drug therapy
Diabetes Mellitus, Type 2/*drug therapy
Glyburide/*pharmacology
Hypoglycemic Agents/*pharmacology
Matrix Metalloproteinase 9/*physiology
Potassium Channels, Inwardly Rectifying/*antagonists & inhibitors
Receptors, Drug/*antagonists & inhibitors
Tissue Plasminogen Activator/*pharmacology
ATP-Binding Cassette Transporters/physiology ; Animals ; Antioxidants/therapeutic use ; Aspirin/adverse effects ; Aspirin/therapeutic use ; Brain Ischemia/complications ; Cells, Cultured/enzymology ; Cerebral Hemorrhage/etiology ; Cerebral Hemorrhage/prevention & control ; Clinical Trials as Topic ; Diabetes Mellitus, Type 2/complications ; Drug Synergism ; Endothelial Cells/enzymology ; Glyburide/therapeutic use ; Heparin/adverse effects ; Heparin/therapeutic use ; Humans ; Hypoglycemic Agents/therapeutic use ; Matrix Metalloproteinase 9/deficiency ; Mice ; Mice, Knockout ; Potassium Channels, Inwardly Rectifying/physiology ; Prospective Studies ; Receptors, Drug/physiology ; Recombinant Proteins/adverse effects ; Recombinant Proteins/pharmacology ; Recombinant Proteins/therapeutic use ; Retrospective Studies ; Risk ; Sulfonylurea Receptors ; Tetracycline/pharmacology ; Tetracycline/therapeutic use ; Tissue Plasminogen Activator/adverse effects ; Tissue Plasminogen Activator/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
K(ATP) channel openers in the trigeminovascular system.
Autorzy:
Ploug KB; Glostrup Research Institute, Denmark.
Amrutkar DV
Baun M
Ramachandran R
Iversen A
Lund TM
Gupta S
Hay-Schmidt A
Olesen J
Jansen-Olesen I
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Źródło:
Cephalalgia : an international journal of headache [Cephalalgia] 2012 Jan; Vol. 32 (1), pp. 55-65. Date of Electronic Publication: 2011 Dec 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP-Binding Cassette Transporters/*genetics
KATP Channels/*genetics
Migraine Disorders/*physiopathology
Potassium Channels, Inwardly Rectifying/*genetics
Receptors, Drug/*genetics
Trigeminal Caudal Nucleus/*physiology
Trigeminal Ganglion/*physiology
ATP-Binding Cassette Transporters/metabolism ; Animals ; Calcitonin Gene-Related Peptide/metabolism ; Cell Degranulation/drug effects ; Cell Degranulation/physiology ; Cromakalim/pharmacology ; Diazoxide/pharmacology ; Disease Models, Animal ; Dura Mater/blood supply ; Dura Mater/cytology ; KATP Channels/metabolism ; Male ; Mast Cells/drug effects ; Mast Cells/metabolism ; Migraine Disorders/chemically induced ; Potassium Channels, Inwardly Rectifying/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, Drug/metabolism ; Sulfonylurea Receptors ; Trigeminal Caudal Nucleus/blood supply ; Trigeminal Caudal Nucleus/drug effects ; Trigeminal Ganglion/blood supply ; Trigeminal Ganglion/drug effects ; Vasodilator Agents/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The common C49620T polymorphism in the sulfonylurea receptor gene SUR1 (ABCC8) in patients with gestational diabetes and subsequent glucose metabolism abnormalities.
Autorzy:
Molęda P; Department of Diabetology and Internal Diseases, Pomeranian Medical University, Szczecin, Poland. />Bińczak-Kuleta A
Homa K
Safranow K
Celewicz Z
Syrenicz A
Stefański A
Fronczyk A
Majkowska L
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Źródło:
Experimental diabetes research [Exp Diabetes Res] 2012; Vol. 2012, pp. 712617. Date of Electronic Publication: 2012 Aug 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Polymorphism, Genetic*
ATP-Binding Cassette Transporters/*genetics
Diabetes, Gestational/*genetics
Glucose/*metabolism
Potassium Channels, Inwardly Rectifying/*genetics
Receptors, Drug/*genetics
ATP-Binding Cassette Transporters/metabolism ; Adult ; Anthropometry ; Blood Glucose/metabolism ; Diabetes, Gestational/metabolism ; Female ; Glucose Tolerance Test ; Humans ; Insulin/blood ; Insulin Resistance ; Insulin-Secreting Cells/cytology ; Potassium Channels, Inwardly Rectifying/metabolism ; Pregnancy ; Receptors, Drug/metabolism ; Sulfonylurea Receptors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A role of the sulfonylurea receptor 1 in endocytic trafficking of ATP-sensitive potassium channels.
Autorzy:
Bruederle CE; Department of Biochemistry and Molecular Biology, Oregon Health & Science University, Portland, OR 97239, USA. />Gay J
Shyng SL
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Źródło:
Traffic (Copenhagen, Denmark) [Traffic] 2011 Sep; Vol. 12 (9), pp. 1242-56. Date of Electronic Publication: 2011 Jul 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP-Binding Cassette Transporters/*metabolism
Endocytosis/*physiology
Potassium Channels, Inwardly Rectifying/*metabolism
Protein Subunits/*metabolism
Receptors, Drug/*metabolism
ATP-Binding Cassette Transporters/genetics ; Adenosine Triphosphate/metabolism ; Amino Acid Motifs ; Animals ; Bungarotoxins/metabolism ; COS Cells ; Cell Membrane/metabolism ; Chlorocebus aethiops ; Clathrin/metabolism ; Dynamins/metabolism ; Mutation ; Patch-Clamp Techniques ; Potassium Channels, Inwardly Rectifying/genetics ; Protein Subunits/genetics ; Receptors, Drug/genetics ; Sulfonylurea Receptors ; Transferrin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A key role for the subunit SUR2B in the preferential activation of vascular KATP channels by isoflurane.
Autorzy:
Fujita H; Department of Pharmacology, Chiba University Graduate School of Medicine, Chuo-ku, Chiba, Japan.
Ogura T
Tamagawa M
Uemura H
Sato T
Ishida A
Imamaki M
Kimura F
Miyazaki M
Nakaya H
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2006 Nov; Vol. 149 (5), pp. 573-80. Date of Electronic Publication: 2006 Sep 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP-Binding Cassette Transporters/*physiology
G Protein-Coupled Inwardly-Rectifying Potassium Channels/*physiology
Isoflurane/*pharmacology
Potassium Channels/*physiology
Potassium Channels, Inwardly Rectifying/*physiology
Receptors, Drug/*physiology
ATP-Binding Cassette Transporters/genetics ; Anesthetics, Inhalation/pharmacology ; Animals ; Aorta, Thoracic/drug effects ; Aorta, Thoracic/physiology ; Cell Line ; Cells, Cultured ; Coronary Circulation/drug effects ; Dose-Response Relationship, Drug ; G Protein-Coupled Inwardly-Rectifying Potassium Channels/genetics ; Glyburide/pharmacology ; Humans ; In Vitro Techniques ; Membrane Potentials/drug effects ; Membrane Potentials/physiology ; Mice ; Mice, Inbred C57BL ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/physiology ; Patch-Clamp Techniques/methods ; Pinacidil/pharmacology ; Potassium Channels/genetics ; Potassium Channels, Inwardly Rectifying/genetics ; Receptors, Drug/genetics ; Sulfonylurea Receptors ; Theophylline/pharmacology ; Transfection/methods ; Vasodilation/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating.
Autorzy:
Bienengraeber M; Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, Minnesota 55905, USA.
Olson TM
Selivanov VA
Kathmann EC
O'Cochlain F
Gao F
Karger AB
Ballew JD
Hodgson DM
Zingman LV
Pang YP
Alekseev AE
Terzic A
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Źródło:
Nature genetics [Nat Genet] 2004 Apr; Vol. 36 (4), pp. 382-7. Date of Electronic Publication: 2004 Mar 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Mutation*
Potassium Channels, Inwardly Rectifying*
ATP-Binding Cassette Transporters/*genetics
Cardiomyopathy, Dilated/*genetics
Ion Channel Gating/*genetics
Potassium Channels/*genetics
Receptors, Drug/*genetics
Adult ; Amino Acid Sequence ; Animals ; Catalysis ; Female ; Humans ; Male ; Middle Aged ; Molecular Sequence Data ; Sequence Homology, Amino Acid ; Sulfonylurea Receptors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Interaction of a novel dihydropyridine K+ channel opener, A-312110, with recombinant sulphonylurea receptors and KATP channels: comparison with the cyanoguanidine P1075.
Autorzy:
Felsch H; Department of Pharmacology and Toxicology, Medical Faculty, University of Tübingen, Wilhelmstr. 56, D-72074 Tuebingen, Germany.
Lange U
Hambrock A
Löffler-Walz C
Russ U
Carroll WA
Gopalakrishnan M
Quast U
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2004 Apr; Vol. 141 (7), pp. 1098-105. Date of Electronic Publication: 2004 Mar 15.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP-Binding Cassette Transporters/*drug effects
Drug Interactions/*physiology
Guanidines/*pharmacology
Membrane Proteins/*drug effects
Potassium Channels/*drug effects
Potassium Channels/*physiology
Potassium Channels, Inwardly Rectifying/*drug effects
Pyridines/*pharmacology
Receptors, Drug/*drug effects
Thiophenes/*pharmacology
ATP-Binding Cassette Transporters/genetics ; Adenosine Triphosphate/chemistry ; Adenosine Triphosphate/metabolism ; Cell Line ; Dihydropyridines/chemistry ; Dihydropyridines/pharmacology ; Guanidines/chemistry ; Humans ; Ion Channel Gating ; Kidney/cytology ; Kidney/embryology ; Magnesium/chemistry ; Magnesium/metabolism ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Muscle Fibers, Skeletal/cytology ; Muscle Fibers, Skeletal/drug effects ; Muscle Fibers, Skeletal/metabolism ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Patch-Clamp Techniques/methods ; Potassium Channels/genetics ; Potassium Channels, Inwardly Rectifying/genetics ; Pyridines/chemistry ; Receptors, Drug/genetics ; Recombinant Proteins/drug effects ; Recombinant Proteins/genetics ; Sulfonylurea Receptors ; Thiophenes/chemistry ; Tritium
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
[Study on the relationship between sulfonylurea receptor 1 gene polymorphism and type 2 diabetes mellitus].
Autorzy:
Wang JS; Department of Epidemiology, Nanjing Medical University, Nanjing 210029, China. />Zhou L
Cheng JL
Shen MY
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Źródło:
Yi chuan = Hereditas [Yi Chuan] 2004 Jan; Vol. 26 (1), pp. 8-12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Polymorphism, Genetic*
ATP-Binding Cassette Transporters/*genetics
Diabetes Mellitus, Type 2/*genetics
Exons/*genetics
Potassium Channels, Inwardly Rectifying/*genetics
Receptors, Drug/*genetics
ATP-Binding Cassette Transporters/blood ; Adult ; Alleles ; Diabetes Mellitus, Type 2/blood ; Female ; Gene Frequency ; Genetic Predisposition to Disease ; Genotype ; Humans ; Male ; Middle Aged ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length ; Potassium Channels, Inwardly Rectifying/blood ; Receptors, Drug/blood ; Sulfonylurea Receptors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion.
Autorzy:
Kahle KT; Howard Hughes Medical Institute, 300 Cedar Street, TAC S-341D, and Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
Wilson FH
Leng Q
Lalioti MD
O'Connell AD
Dong K
Rapson AK
MacGregor GG
Giebisch G
Hebert SC
Lifton RP
Pokaż więcej
Źródło:
Nature genetics [Nat Genet] 2003 Dec; Vol. 35 (4), pp. 372-6. Date of Electronic Publication: 2003 Nov 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Potassium Channels, Inwardly Rectifying*
Receptors, Drug*
Symporters*
Kidney/*physiology
Potassium/*metabolism
Protein Serine-Threonine Kinases/*physiology
Sodium Chloride/*metabolism
Animals ; Carrier Proteins/antagonists & inhibitors ; Carrier Proteins/metabolism ; Clathrin/metabolism ; Endocytosis ; Green Fluorescent Proteins ; Ion Transport ; Luminescent Proteins/metabolism ; Mice ; Potassium Channels/metabolism ; Pseudohypoaldosteronism/metabolism ; Rats ; Sodium Chloride Symporters ; Solute Carrier Family 12, Member 3 ; Xenopus laevis/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Functional involvement of sulphonylurea receptor (SUR) type 1 and 2B in the activity of pig urethral ATP-sensitive K+ channels.
Autorzy:
Yunoki T; Department of Pharmacology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi Ward, Fukuoka 812-8582, Japan.
Teramoto N
Ito Y
Pokaż więcej
Źródło:
British journal of pharmacology [Br J Pharmacol] 2003 Jun; Vol. 139 (3), pp. 652-60.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Potassium Channels, Inwardly Rectifying*
ATP-Binding Cassette Transporters/*metabolism
Adenosine Triphosphate/*metabolism
Potassium Channels/*metabolism
Receptors, Drug/*metabolism
Urethra/*metabolism
ATP-Binding Cassette Transporters/agonists ; ATP-Binding Cassette Transporters/antagonists & inhibitors ; Animals ; Female ; Gliclazide/pharmacology ; Imidazoles/pharmacology ; Muscle Cells/drug effects ; Muscle Cells/metabolism ; Potassium Channels/agonists ; Receptors, Drug/agonists ; Receptors, Drug/antagonists & inhibitors ; Sulfonylurea Receptors ; Swine ; Thioamides/pharmacology ; Urethra/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mg2+ sensitizes KATP channels to inhibition by DIDS: dependence on the sulphonylurea receptor subunit.
Autorzy:
Gojkovic-Bukarica L; Department of Pharmacology and Toxicology, Medical Faculty, University of Tübingen, Wilhelmstr. 56, Germany.
Hambrock A
Löffler-Walz C
Quast U
Russ U
Pokaż więcej
Źródło:
British journal of pharmacology [Br J Pharmacol] 2002 Oct; Vol. 137 (4), pp. 429-40.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP-Binding Cassette Transporters*
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid/*pharmacology
Magnesium/*pharmacology
Potassium Channels/*physiology
Potassium Channels, Inwardly Rectifying/*antagonists & inhibitors
Protein Subunits/*antagonists & inhibitors
Protein Subunits/*physiology
Receptors, Drug/*antagonists & inhibitors
Receptors, Drug/*physiology
Cell Line ; Dose-Response Relationship, Drug ; Humans ; Potassium Channels, Inwardly Rectifying/physiology ; Sulfonylurea Receptors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Molecular physiology of neuronal K-ATP channels (review).
Autorzy:
Liss B; MRC Anatomical Neuropharmacology Unit, University of Oxford, UK.
Roeper J
Pokaż więcej
Źródło:
Molecular membrane biology [Mol Membr Biol] 2001 Apr-Jun; Vol. 18 (2), pp. 117-27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Potassium Channels, Inwardly Rectifying*
ATP-Binding Cassette Transporters/*physiology
Potassium Channels/*physiology
Receptors, Drug/*physiology
ATP-Binding Cassette Transporters/metabolism ; Animals ; Humans ; Hypoxia-Ischemia, Brain/metabolism ; Neurodegenerative Diseases/metabolism ; Potassium Channels/metabolism ; Receptors, Drug/metabolism ; Sulfonylurea Receptors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 41

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