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Wyświetlanie 1-4 z 4
Tytuł :
Excess glucose induce trophoblast inflammation and limit cell migration through HMGB1 activation of Toll-Like receptor 4.
Autorzy :
Heim KR; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, Connecticut.
Mulla MJ; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, Connecticut.
Potter JA; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, Connecticut.
Han CS; Department of Obstetrics & Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California.
Guller S; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, Connecticut.
Abrahams VM; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, Connecticut.
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Źródło :
American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2018 Nov; Vol. 80 (5), pp. e13044. Date of Electronic Publication: 2018 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alarmins/*metabolism
HMGB1 Protein/*metabolism
Hyperglycemia/*immunology
Inflammation/*immunology
Pre-Eclampsia/*immunology
Toll-Like Receptor 4/*metabolism
Trophoblasts/*immunology
Cell Line ; Cell Movement ; Female ; Glycyrrhizic Acid/pharmacology ; HMGB1 Protein/antagonists & inhibitors ; Humans ; Interleukin-1beta/metabolism ; Interleukin-8/metabolism ; Pregnancy ; Risk ; Signal Transduction ; Trophoblasts/pathology ; Vascular Endothelial Growth Factor Receptor-1/metabolism
Czasopismo naukowe
Tytuł :
Magnesium sulfate differentially modulates fetal membrane inflammation in a time-dependent manner.
Autorzy :
Cross SN; Department of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA.
Nelson RA; Department of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA.
Potter JA; Department of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA.
Norwitz ER; Department of Obstetrics & Gynecology, Tufts University School of Medicine, Boston, MA, USA.
Abrahams VM; Department of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA.
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Źródło :
American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2018 Jul; Vol. 80 (1), pp. e12861. Date of Electronic Publication: 2018 Apr 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Extraembryonic Membranes/*drug effects
Inflammation/*drug therapy
Magnesium Sulfate/*pharmacology
Caspase 1/metabolism ; Chorioamnionitis/metabolism ; Cytokines/metabolism ; Extraembryonic Membranes/metabolism ; Female ; Humans ; Inflammation/metabolism ; Interleukin-1beta/metabolism ; Pregnancy ; Premature Birth/prevention & control ; Time Factors ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Viral single stranded RNA induces a trophoblast pro-inflammatory and antiviral response in a TLR8-dependent and -independent manner.
Autorzy :
Potter JA; Department of Obstetrics, Gynecology, & Reproductive Sciences, Divisions of Reproductive Sciences and Maternal-Fetal Medicine, Yale School of Medicine, New Haven, Connecticut.
Garg M; Maternal and Fetal Health Research Centre, University of Manchester, Manchester, United Kingdom.
Girard S; Department of Obstetrics, Gynecology, & Reproductive Sciences, Divisions of Reproductive Sciences and Maternal-Fetal Medicine, Yale School of Medicine, New Haven, Connecticut Maternal and Fetal Health Research Centre, University of Manchester, Manchester, United Kingdom.
Abrahams VM; Department of Obstetrics, Gynecology, & Reproductive Sciences, Divisions of Reproductive Sciences and Maternal-Fetal Medicine, Yale School of Medicine, New Haven, Connecticut .
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Źródło :
Biology of reproduction [Biol Reprod] 2015 Jan; Vol. 92 (1), pp. 17. Date of Electronic Publication: 2014 Nov 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Immunity, Innate*
Inflammation*/immunology
RNA, Viral/*physiology
Toll-Like Receptor 8/*physiology
Trophoblasts/*immunology
Animals ; Caspase 3/metabolism ; Cells, Cultured ; Female ; Humans ; Mice ; Mice, Inbred ICR ; Myeloid Differentiation Factor 88/physiology ; Pregnancy ; Pregnancy Complications, Infectious/immunology ; Trophoblasts/virology
Czasopismo naukowe
Tytuł :
Human endometrial endothelial cells generate distinct inflammatory and antiviral responses to the TLR3 agonist, Poly(I:C) and the TLR8 agonist, viral ssRNA.
Autorzy :
Krikun G; Department of Obstetrics, Gynecology & Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA.
Potter JA
Abrahams VM
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Źródło :
American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2013 Sep; Vol. 70 (3), pp. 190-8. Date of Electronic Publication: 2013 Apr 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antiviral Agents/*metabolism
Endometrium/*immunology
Endothelial Cells/*cytology
Endothelial Cells/*immunology
Inflammation/*immunology
Poly I-C/*pharmacology
RNA, Viral/*pharmacology
Toll-Like Receptor 3/*agonists
Toll-Like Receptor 8/*agonists
Cells, Cultured ; Cytokines/metabolism ; Endometrium/cytology ; Endometrium/drug effects ; Endothelial Cells/drug effects ; Female ; Humans ; Poly I-C/genetics ; Poly I-C/immunology ; RNA, Viral/genetics ; RNA, Viral/immunology ; Toll-Like Receptor 3/metabolism ; Toll-Like Receptor 8/metabolism
Czasopismo naukowe
    Wyświetlanie 1-4 z 4

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