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Wyszukujesz frazę ""Pravastatin"" wg kryterium: Temat


Tytuł :
Cholesterol partially rescues the inhibition effect of pravastatin on keratinocytes proliferation by regulating cell cycle relative proteins through AKT and ERK pathway.
Autorzy :
Li M; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Jin R; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Qi Y; General Department of Hyperbaric Oxygen, Affiliated Hefei Hospital of Anhui Medical University, Hefei, Anhui, China.
Zhou H; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Zhu T; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Liu L; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Gu Y; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Luan K; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Luo X; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Zhang S; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
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Źródło :
Dermatologic therapy [Dermatol Ther] 2020 Nov; Vol. 33 (6), pp. e14305. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology
Pravastatin*/pharmacology
Cell Cycle ; Cell Cycle Proteins ; Cell Proliferation ; Cholesterol ; Humans ; Keratinocytes/metabolism ; MAP Kinase Signaling System ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł :
Pravastatin alleviates intracellular calcium dysregulation induced by Interleukin-6 via the mitochondrial ROS pathway in adult ventricular myocytes.
Autorzy :
Zuo S; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Li L; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Jiang L; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Jiang C; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Li X; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Li S; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Wen S; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Bai R; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Du X; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Dong J; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Liu N; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Ruan Y; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China. Electronic address: .
Ma C; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Jul; Vol. 143 (3), pp. 141-147. Date of Electronic Publication: 2020 Feb 29.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiotonic Agents*
Calcium/*metabolism
Heart Ventricles/*cytology
Interleukin-6/*adverse effects
Mitochondria/*metabolism
Myocytes, Cardiac/*metabolism
Pravastatin/*pharmacology
Reactive Oxygen Species/*metabolism
Signal Transduction/*drug effects
Signal Transduction/*physiology
Animals ; Cardiomyopathies/drug therapy ; Cells, Cultured ; Inflammation ; Male ; Mice ; Mice, Inbred C57BL ; Pravastatin/administration & dosage ; Sarcoplasmic Reticulum/metabolism
Czasopismo naukowe
Tytuł :
Re: Pravastatin for early-onset pre-eclampsia: a randomised, blinded, placebo-controlled trial.
Autorzy :
Voto LS; Departamento Materno infantil, Hospital General de Agudos Dr. Juan A. Fernández, Ciudad de Buenos Aires, Argentina.
Zeitune MG; Departamento Materno infantil, Hospital General de Agudos Dr. Juan A. Fernández, Ciudad de Buenos Aires, Argentina.
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Źródło :
BJOG : an international journal of obstetrics and gynaecology [BJOG] 2020 Jul; Vol. 127 (8), pp. 1036. Date of Electronic Publication: 2020 May 05.
Typ publikacji :
Letter; Comment
MeSH Terms :
Pravastatin*
Pre-Eclampsia*
Dietary Supplements ; Double-Blind Method ; Female ; Humans ; Pregnancy
Opinia redakcyjna
Tytuł :
Effect of Statin on Stroke Recurrence Prevention at Different Infarction Locations: A Post Hoc Analysis of The J-STARS Study.
Autorzy :
Nezu T; Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences.
Hosomi N; Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences.
Kitagawa K; Department of Neurology, Tokyo Women's Medical University School of Medicine.
Nagai Y; Center for Clinical Research, Kobe University Hospital.
Nakagawa Y; Division of Medical Statistics, Translational Research Informatics Center, Foundation for Biomedical Research and Innovation.
Aoki S; Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences.
Kagimura T; Division of Medical Statistics, Translational Research Informatics Center, Foundation for Biomedical Research and Innovation.
Maruyama H; Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences.
Origasa H; Division of Biostatistics and Clinical Epidemiology, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences.
Minematsu K; National Cerebral and Cardiovascular Center.
Uchiyama S; Clinical Research Center for Medicine, International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center.
Matsumoto M; Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences.; Sakai City Medical Center, Sakai City Hospital Organization.
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Corporate Authors :
J-STARS collaborators
Źródło :
Journal of atherosclerosis and thrombosis [J Atheroscler Thromb] 2020 Jun 01; Vol. 27 (6), pp. 524-533. Date of Electronic Publication: 2019 Sep 25.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Brain Infarction*/diagnosis
Brain Infarction*/physiopathology
Brain Infarction*/therapy
Ischemic Stroke*/epidemiology
Ischemic Stroke*/prevention & control
Pravastatin*/administration & dosage
Pravastatin*/adverse effects
Brain/*blood supply
Aged ; Cerebrovascular Circulation/drug effects ; Female ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Incidence ; Male ; Outcome Assessment, Health Care ; Proportional Hazards Models ; Recurrence ; Secondary Prevention
Czasopismo naukowe
Tytuł :
Interaction of Oatp1b2 expression and nonalcoholic steatohepatitis on pravastatin plasma clearance.
Autorzy :
Toth EL; Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ 85721, United States.
Clarke JD; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, United States.
Csanaky IL; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation & Division of Gastroenterology, Children's Mercy Hospital, Kansas City, MO 64108, United States; Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS 66160, United States.
Cherrington NJ; Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ 85721, United States. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2020 Apr; Vol. 174, pp. 113780. Date of Electronic Publication: 2019 Dec 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression*
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*blood
Liver-Specific Organic Anion Transporter 1/*genetics
Non-alcoholic Fatty Liver Disease/*drug therapy
Pravastatin/*blood
Animals ; Disease Models, Animal ; Gene Dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Metabolic Clearance Rate ; Mice, Inbred C57BL ; Mice, Knockout ; Non-alcoholic Fatty Liver Disease/blood ; Non-alcoholic Fatty Liver Disease/genetics ; Pravastatin/therapeutic use
Czasopismo naukowe
Tytuł :
The rising cost of commonly used emergency department medications (2006-15).
Autorzy :
Tebo C; Georgetown University School of Medicine, Washington, DC, United States of America. Electronic address: .
Mazer-Amirshahi M; Georgetown University School of Medicine, Washington, DC, United States of America; Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC, United States of America. Electronic address: .
Zocchi MS; Heller School for Social Policy and Management, Brandeis University, Boston, MA, United States of America.
Gibson C; Georgetown University School of Medicine, Washington, DC, United States of America. Electronic address: .
Rosenwohl-Mack S; University of California, San Francisco, CA, United States of America. Electronic address: .
Hsia RY; University of California, San Francisco, CA, United States of America.
Fox ER; University of Utah, United States of America. Electronic address: .
Nelson LS; Rutgers New Jersey Medical School, Newark, NJ, United States of America.
Pines JM; US Acute Care Solutions, Canton, OH, United States of America.
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Źródło :
The American journal of emergency medicine [Am J Emerg Med] 2021 Apr; Vol. 42, pp. 137-142. Date of Electronic Publication: 2020 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Costs*
Emergency Service, Hospital/*economics
Prescription Drugs/*economics
Cross-Sectional Studies ; Epinephrine/economics ; Glucagon/economics ; Humans ; Pantoprazole/economics ; Patient Discharge ; Pravastatin/economics ; United States
Czasopismo naukowe
Tytuł :
Statins for atherosclerotic cardiovascular disease prevention in people living with HIV in Thailand: a cost-effectiveness analysis.
Autorzy :
Boettiger DC; Kirby Institute, UNSW Sydney, Sydney, NSW, Australia.; Institute for Health Policy Studies, University of California, San Francisco, CA, USA.
Newall AT; The School of Public Health and Community Medicine, UNSW Sydney, Sydney, NSW, Australia.
Chattranukulchai P; Cardiac Center, Chulalongkorn University, Chulalongkorn Memorial Hospital, King, Bangkok, Thailand.
Chaiwarith R; Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Khusuwan S; Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand.
Avihingsanon A; The Thai Red Cross AIDS Research Centre and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Phillips A; Institute for Global Health, University College London, United Kingdom.
Bendavid E; Center for Health Policy and the Center for Primary Care and Outcomes Research, Stanford University, Stanford, CA, USA.
Law MG; Kirby Institute, UNSW Sydney, Sydney, NSW, Australia.
Kahn JG; Institute for Health Policy Studies, University of California, San Francisco, CA, USA.
Ross J; TREAT Asia/amfAR-Foundation for AIDS Research, Bangkok, Thailand.
Bautista-Arredondo S; Center for Health Systems Research, National Institute of Public Health, Cuernavaca, Mexico.
Kiertiburanakul S; Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
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Źródło :
Journal of the International AIDS Society [J Int AIDS Soc] 2020 Jun; Vol. 23 Suppl 1, pp. e25494.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Atherosclerosis/*prevention & control
HIV Infections/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Pravastatin/*therapeutic use
Quinolines/*therapeutic use
Adult ; Atherosclerosis/complications ; Cost-Benefit Analysis ; Drug Costs ; Female ; HIV Infections/complications ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/economics ; Male ; Middle Aged ; Pravastatin/economics ; Quality-Adjusted Life Years ; Quinolines/economics ; Thailand
Czasopismo naukowe
Tytuł :
Re: Pravastatin to ameliorate early-onset pre-eclampsia: promising but not there yet.
Autorzy :
Gueta I; The Institute of Clinical Pharmacology and Toxicology, Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Schacham YN; The Institute of Clinical Pharmacology and Toxicology, Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Markovits N; The Institute of Clinical Pharmacology and Toxicology, Chaim Sheba Medical Center, Ramat Gan, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Źródło :
BJOG : an international journal of obstetrics and gynaecology [BJOG] 2020 May; Vol. 127 (6), pp. 774-775. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Letter; Comment
MeSH Terms :
Pravastatin*
Pre-Eclampsia*
Female ; Humans ; Pregnancy
Opinia redakcyjna
Tytuł :
Pravastatin as the statin of choice for reducing pre-eclampsia-associated endothelial dysfunction.
Autorzy :
de Alwis N; Therapeutics Discovery and Vascular Function in Pregnancy Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Translational Obstetrics Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Mercy Perinatal, Mercy Hospital for Women, Heidelberg 3084, Victoria, Australia.
Beard S; Therapeutics Discovery and Vascular Function in Pregnancy Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Translational Obstetrics Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Mercy Perinatal, Mercy Hospital for Women, Heidelberg 3084, Victoria, Australia.
Mangwiro YT; Therapeutics Discovery and Vascular Function in Pregnancy Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Translational Obstetrics Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Mercy Perinatal, Mercy Hospital for Women, Heidelberg 3084, Victoria, Australia.
Binder NK; Therapeutics Discovery and Vascular Function in Pregnancy Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Translational Obstetrics Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Mercy Perinatal, Mercy Hospital for Women, Heidelberg 3084, Victoria, Australia.
Kaitu'u-Lino TJ; Translational Obstetrics Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Mercy Perinatal, Mercy Hospital for Women, Heidelberg 3084, Victoria, Australia.
Brownfoot FC; Translational Obstetrics Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Mercy Perinatal, Mercy Hospital for Women, Heidelberg 3084, Victoria, Australia.
Tong S; Translational Obstetrics Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Mercy Perinatal, Mercy Hospital for Women, Heidelberg 3084, Victoria, Australia.
Hannan NJ; Therapeutics Discovery and Vascular Function in Pregnancy Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Translational Obstetrics Group, Department of Obstetrics and Gynaecology, University of Melbourne, Australia; Mercy Perinatal, Mercy Hospital for Women, Heidelberg 3084, Victoria, Australia. Electronic address: .
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Źródło :
Pregnancy hypertension [Pregnancy Hypertens] 2020 Apr; Vol. 20, pp. 83-91. Date of Electronic Publication: 2020 Mar 04.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Endothelium, Vascular/*drug effects
Human Umbilical Vein Endothelial Cells/*drug effects
Pravastatin/*pharmacology
Pre-Eclampsia/*drug therapy
Cell Survival/drug effects ; Cells, Cultured ; Endothelin-1/genetics ; Endothelin-1/metabolism ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/physiopathology ; Female ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Pravastatin/toxicity ; Pre-Eclampsia/genetics ; Pre-Eclampsia/metabolism ; Pre-Eclampsia/physiopathology ; Pregnancy ; Rosuvastatin Calcium/pharmacology ; Simvastatin/pharmacology ; Vascular Cell Adhesion Molecule-1/genetics ; Vascular Cell Adhesion Molecule-1/metabolism ; Vascular Endothelial Growth Factor Receptor-1/metabolism
Czasopismo naukowe
Tytuł :
Pravastatin Alleviates Radiation Proctitis by Regulating Thrombomodulin in Irradiated Endothelial Cells.
Autorzy :
Jang H; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kwak SY; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Park S; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.; Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kim K; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kim YH; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Na J; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kim H; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Jang WS; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Lee SJ; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kim MJ; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Myung JK; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.; Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Shim S; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Mar 10; Vol. 21 (5). Date of Electronic Publication: 2020 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Cells/*cytology
Pravastatin/*administration & dosage
Proctitis/*drug therapy
Thrombomodulin/*metabolism
Animals ; Disease Models, Animal ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Endothelial Cells/radiation effects ; Female ; Gene Expression Regulation/drug effects ; Human Umbilical Vein Endothelial Cells ; Humans ; Leukocytes/drug effects ; Leukocytes/metabolism ; Mice ; Pravastatin/pharmacology ; Proctitis/etiology ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Statins Reverse Postpartum Cardiovascular Dysfunction in a Rat Model of Preeclampsia.
Autorzy :
Kräker K; From the Experimental and Clinical Research Center-a joint cooperation between the Max Delbrück Center for Molecular Medicine and the Charité-Universitätsmedizin Berlin, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Berlin Institute of Health, Germany (K.K., T.S., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; German Centre for Cardiovascular Research, partner site Berlin, Germany (K.K., T.S., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (K.K., F.H., M.G., S.G., A.B., A.H., D.N.M., N.H.).
O'Driscoll JM; Molecular and Clinical Sciences Research Institute, St George's, University of London, United Kingdom (J.M.O., O.P., B.T.).; Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, United Kingdom (J.M.O., O.P., B.T.).; Canterbury Christ Church University, School of Human and Life Sciences, Kent, United Kingdom (J.M.O.).
Schütte T; Berlin Institute of Health, Germany (K.K., T.S., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; German Centre for Cardiovascular Research, partner site Berlin, Germany (K.K., T.S., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Institute of Pharmacology (T.S.), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany.
Herse F; From the Experimental and Clinical Research Center-a joint cooperation between the Max Delbrück Center for Molecular Medicine and the Charité-Universitätsmedizin Berlin, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (K.K., F.H., M.G., S.G., A.B., A.H., D.N.M., N.H.).
Patey O; Molecular and Clinical Sciences Research Institute, St George's, University of London, United Kingdom (J.M.O., O.P., B.T.).; Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, United Kingdom (J.M.O., O.P., B.T.).
Golic M; From the Experimental and Clinical Research Center-a joint cooperation between the Max Delbrück Center for Molecular Medicine and the Charité-Universitätsmedizin Berlin, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Berlin Institute of Health, Germany (K.K., T.S., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; German Centre for Cardiovascular Research, partner site Berlin, Germany (K.K., T.S., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (K.K., F.H., M.G., S.G., A.B., A.H., D.N.M., N.H.).
Geisberger S; From the Experimental and Clinical Research Center-a joint cooperation between the Max Delbrück Center for Molecular Medicine and the Charité-Universitätsmedizin Berlin, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Berlin Institute of Health, Germany (K.K., T.S., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; German Centre for Cardiovascular Research, partner site Berlin, Germany (K.K., T.S., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (K.K., F.H., M.G., S.G., A.B., A.H., D.N.M., N.H.).
Verlohren S; Institute of Obstetrics (S.V.), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany.
Birukov A; From the Experimental and Clinical Research Center-a joint cooperation between the Max Delbrück Center for Molecular Medicine and the Charité-Universitätsmedizin Berlin, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Berlin Institute of Health, Germany (K.K., T.S., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; German Centre for Cardiovascular Research, partner site Berlin, Germany (K.K., T.S., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (K.K., F.H., M.G., S.G., A.B., A.H., D.N.M., N.H.).
Heuser A; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (K.K., F.H., M.G., S.G., A.B., A.H., D.N.M., N.H.).
Müller DN; From the Experimental and Clinical Research Center-a joint cooperation between the Max Delbrück Center for Molecular Medicine and the Charité-Universitätsmedizin Berlin, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Berlin Institute of Health, Germany (K.K., T.S., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; German Centre for Cardiovascular Research, partner site Berlin, Germany (K.K., T.S., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (K.K., F.H., M.G., S.G., A.B., A.H., D.N.M., N.H.).
Thilaganathan B; Molecular and Clinical Sciences Research Institute, St George's, University of London, United Kingdom (J.M.O., O.P., B.T.).; Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, United Kingdom (J.M.O., O.P., B.T.).
Dechend R; From the Experimental and Clinical Research Center-a joint cooperation between the Max Delbrück Center for Molecular Medicine and the Charité-Universitätsmedizin Berlin, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Berlin Institute of Health, Germany (K.K., T.S., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; German Centre for Cardiovascular Research, partner site Berlin, Germany (K.K., T.S., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; HELIOS-Klinikum, Berlin, Germany (R.D.).
Haase N; From the Experimental and Clinical Research Center-a joint cooperation between the Max Delbrück Center for Molecular Medicine and the Charité-Universitätsmedizin Berlin, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Berlin Institute of Health, Germany (K.K., T.S., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; German Centre for Cardiovascular Research, partner site Berlin, Germany (K.K., T.S., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (K.K., F.H., M.G., S.G., A.B., D.N.M., R.D., N.H.).; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (K.K., F.H., M.G., S.G., A.B., A.H., D.N.M., N.H.).
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Źródło :
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2020 Jan; Vol. 75 (1), pp. 202-210. Date of Electronic Publication: 2019 Dec 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiovascular Diseases/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Pravastatin/*therapeutic use
Pre-Eclampsia/*physiopathology
Ventricular Remodeling/*drug effects
Animals ; Cardiac Output/drug effects ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/physiopathology ; Disease Models, Animal ; Female ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Postpartum Period ; Pravastatin/pharmacology ; Pregnancy ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Pravastatin to ameliorate early-onset pre-eclampsia: promising but not there yet.
Autorzy :
Costantine MM; Department of Obstetrics and Gynecology, The Ohio State University, Columbus, OH, USA.
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Źródło :
BJOG : an international journal of obstetrics and gynaecology [BJOG] 2020 Mar; Vol. 127 (4), pp. 489. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Pravastatin*
Pre-Eclampsia*
Female ; Humans ; Pregnancy
Czasopismo naukowe
Tytuł :
A systematic review on pharmacokinetics, cardiovascular outcomes and safety profiles of statins in cirrhosis.
Autorzy :
Sung S; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada. .
Al-Karaghouli M; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Kalainy S; Alberta Health Services, Edmonton, AB, Canada.
Cabrera Garcia L; Faculty of Medicine, Complutense University of Madrid, Madrid, Spain.
Abraldes JG; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada. .; Division of Gastroenterology, 1-38 Zeidler Ledcor Centre, University of Alberta, 8540 112 St NW, Edmonton, AB, T6G 2X8, Canada. .
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Źródło :
BMC gastroenterology [BMC Gastroenterol] 2021 Mar 16; Vol. 21 (1), pp. 120. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects
Atorvastatin ; Humans ; Liver Cirrhosis/complications ; Liver Cirrhosis/drug therapy ; Pravastatin ; Simvastatin/adverse effects
Czasopismo naukowe
Tytuł :
Evaluation of Pharmacokinetic Drug Interactions of the Direct-Acting Antiviral Agents Elbasvir and Grazoprevir with Pitavastatin, Rosuvastatin, Pravastatin, and Atorvastatin in Healthy Adults.
Autorzy :
Caro L; Merck & Co., Inc., Kenilworth, NJ, USA. .; Merck & Co., Inc., 770 Sumneytown Pike, WP75B-110, West Point, PA, 19486, USA. .
Prueksaritanont T; Merck & Co., Inc., Kenilworth, NJ, USA.; Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Fandozzi CM; Merck & Co., Inc., Kenilworth, NJ, USA.
Feng HP; Merck & Co., Inc., Kenilworth, NJ, USA.
Guo Z; Merck & Co., Inc., Kenilworth, NJ, USA.
Wolford D; Merck & Co., Inc., Kenilworth, NJ, USA.
Panebianco D; Merck & Co., Inc., Kenilworth, NJ, USA.
Fraser IP; Merck & Co., Inc., Kenilworth, NJ, USA.; Abide Therapeutics, San Diego, CA, USA.
Levine V; Merck & Co., Inc., Kenilworth, NJ, USA.
Swearingen D; Celerion Inc., Tempe, AZ, USA.
Butterton JR; Merck & Co., Inc., Kenilworth, NJ, USA.
Iwamoto M; Merck & Co., Inc., Kenilworth, NJ, USA.
Yeh WW; Merck & Co., Inc., Kenilworth, NJ, USA.
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Źródło :
Clinical drug investigation [Clin Drug Investig] 2021 Feb; Vol. 41 (2), pp. 133-147.
Typ publikacji :
Clinical Trial, Phase I; Comparative Study; Journal Article
MeSH Terms :
Amides/*pharmacokinetics
Antiviral Agents/*pharmacokinetics
Benzofurans/*pharmacokinetics
Carbamates/*pharmacokinetics
Cyclopropanes/*pharmacokinetics
Imidazoles/*pharmacokinetics
Quinoxalines/*pharmacokinetics
Sulfonamides/*pharmacokinetics
ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Adolescent ; Adult ; Atorvastatin/pharmacokinetics ; Drug Interactions ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Proteins/metabolism ; Pravastatin/pharmacokinetics ; Quinolines/pharmacokinetics ; Rosuvastatin Calcium/pharmacokinetics ; Young Adult
Czasopismo naukowe
Tytuł :
Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor- β Signaling in Human Endothelial Cells.
Autorzy :
Ronaldson PT; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona .
Brzica H; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona.
Abdullahi W; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona.
Reilly BG; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona.
Davis TP; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona.
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Źródło :
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2021 Feb; Vol. 376 (2), pp. 148-160. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Human Umbilical Vein Endothelial Cells/*metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology
Organic Anion Transporters/*metabolism
Transforming Growth Factor beta/*metabolism
Activin Receptors, Type II/metabolism ; Atorvastatin/pharmacology ; Growth Differentiation Factor 2/metabolism ; HeLa Cells ; Hep G2 Cells ; Human Umbilical Vein Endothelial Cells/drug effects ; Humans ; Pravastatin/pharmacology ; Rosuvastatin Calcium/pharmacology
Czasopismo naukowe
Tytuł :
UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.
Autorzy :
Courlet P; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Switzerland. Electronic address: .
Spaggiari D; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Switzerland. Electronic address: .
Desfontaine V; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Switzerland. Electronic address: .
Cavassini M; Service of Infectious Diseases, Lausanne University Hospital and University of Lausanne, Switzerland. Electronic address: .
Alves Saldanha S; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Switzerland. Electronic address: .
Buclin T; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Switzerland. Electronic address: .
Marzolini C; Departments of Medicine and Clinical Research, University Hospital of Basel and University of Basel, Switzerland. Electronic address: .
Csajka C; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Switzerland; School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Switzerland. Electronic address: .
Decosterd LA; Service of Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Switzerland. Electronic address: .
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Źródło :
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2019 Sep 01; Vol. 1125, pp. 121733. Date of Electronic Publication: 2019 Jul 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
HIV Infections*/drug therapy
HIV Infections*/metabolism
Amlodipine/*blood
Atorvastatin/*blood
Metoprolol/*blood
Pravastatin/*blood
Rosuvastatin Calcium/*blood
Amlodipine/chemistry ; Amlodipine/metabolism ; Amlodipine/pharmacokinetics ; Anti-HIV Agents/pharmacokinetics ; Anti-HIV Agents/therapeutic use ; Atorvastatin/chemistry ; Atorvastatin/metabolism ; Atorvastatin/pharmacokinetics ; Chromatography, High Pressure Liquid/methods ; Drug Interactions ; Humans ; Linear Models ; Metoprolol/chemistry ; Metoprolol/metabolism ; Metoprolol/pharmacokinetics ; Pravastatin/chemistry ; Pravastatin/metabolism ; Pravastatin/pharmacokinetics ; Reproducibility of Results ; Rosuvastatin Calcium/chemistry ; Rosuvastatin Calcium/metabolism ; Rosuvastatin Calcium/pharmacokinetics ; Sensitivity and Specificity ; Tandem Mass Spectrometry/methods
Czasopismo naukowe
Tytuł :
Biphasic influence of pravastatin on human cardiac microvascular endothelial cell functions under pathological and physiological conditions.
Autorzy :
Hu K; Department of Vascular Surgery, The Second Clinical Medical College, Yangtze University, Jingzhou Central Hospital, Jingzhou, People's Republic of China. Electronic address: .
Wan Q; Department of Thoracic Surgery, Xiantao First People's Hospital, Xiantao, People's Republic of China.
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2019 Apr 02; Vol. 511 (2), pp. 476-481. Date of Electronic Publication: 2019 Feb 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticholesteremic Agents/*pharmacology
Endothelial Cells/*drug effects
Oxidative Stress/*drug effects
Pravastatin/*pharmacology
Anticholesteremic Agents/administration & dosage ; Anticholesteremic Agents/adverse effects ; Cell Line ; Cell Movement/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Heart/drug effects ; Humans ; Myocardium/cytology ; Myocardium/metabolism ; Myocardium/pathology ; Neovascularization, Physiologic/drug effects ; Pravastatin/administration & dosage ; Pravastatin/adverse effects ; Prenylation/drug effects
Czasopismo naukowe
Tytuł :
Triple therapy with pravastatin, low molecular weight heparin and low dose aspirin improves placental haemodynamics and pregnancy outcomes in obstetric antiphospholipid syndrome in mice and women through a nitric oxide-dependent mechanism.
Autorzy :
Lefkou E; Perigenesis, Institute of Obstetric Haematology, Thessaloniki, Greece.
Varoudi K; Perigenesis, Institute of Obstetric Haematology, Thessaloniki, Greece.
Pombo J; MRC London Institute of Medical Sciences - Imperial College, London, UK.
Jurisic A; University of Belgrade Medical School, Narodni Front University Hospital, Belgrade, Serbia.
Jurisic Z; OB/GYN Polyclinic Jurisic, Belgrade, Serbia.
Contento G; Centre for Inflammation and Tissue Repair-UCL Respiratory, London, UK.
Girardi G; King's College London - St Thomas' Hospital, London UK; Department of Basic Medical Sciences, College of Medicine, member of QU Health, Qatar University, Doha, Qatar. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2020 Dec; Vol. 182, pp. 114217. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nitric Oxide*/blood
Antiphospholipid Syndrome/*drug therapy
Aspirin/*administration & dosage
Heparin, Low-Molecular-Weight/*administration & dosage
Pravastatin/*administration & dosage
Pregnancy Complications/*drug therapy
Adult ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage ; Anticholesteremic Agents/administration & dosage ; Anticoagulants/administration & dosage ; Antiphospholipid Syndrome/blood ; Antiphospholipid Syndrome/diagnostic imaging ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Female ; Fetal Growth Retardation/blood ; Fetal Growth Retardation/diagnostic imaging ; Fetal Growth Retardation/drug therapy ; Hemodynamics/drug effects ; Hemodynamics/physiology ; Humans ; Mice ; Mice, Inbred C57BL ; Placenta/blood supply ; Placenta/drug effects ; Placenta/metabolism ; Pre-Eclampsia/blood ; Pre-Eclampsia/diagnostic imaging ; Pre-Eclampsia/drug therapy ; Pregnancy ; Pregnancy Complications/blood ; Pregnancy Complications/diagnostic imaging ; Pregnancy Outcome
Czasopismo naukowe
Tytuł :
Statins Stimulate New Myocyte Formation After Myocardial Infarction by Activating Growth and Differentiation of the Endogenous Cardiac Stem Cells.
Autorzy :
Cianflone E; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Cappetta D; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Mancuso T; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Sabatino J; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Marino F; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Scalise M; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Albanese M; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Salatino A; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Parrotta EI; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Cuda G; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
De Angelis A; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Berrino L; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Rossi F; Department of Experimental Medicine, University of Campania 'L. Vanvitelli', 80138 Naples, Italy.
Nadal-Ginard B; Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Torella D; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Urbanek K; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 26; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage
Muscle Cells/*cytology
Myocardial Infarction/*drug therapy
Myocardium/*cytology
Stem Cells/*drug effects
Animals ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Disease Models, Animal ; Female ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Mice ; Muscle Cells/drug effects ; Muscle Cells/metabolism ; Myocardial Infarction/etiology ; Myocardial Infarction/metabolism ; Myocardium/metabolism ; Phosphorylation/drug effects ; Pravastatin/administration & dosage ; Pravastatin/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rosuvastatin Calcium/administration & dosage ; Rosuvastatin Calcium/pharmacology ; Simvastatin/administration & dosage ; Simvastatin/pharmacology ; Stem Cells/cytology ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
Dual-probe molecular MRI for the in vivo characterization of atherosclerosis in a mouse model: Simultaneous assessment of plaque inflammation and extracellular-matrix remodeling.
Autorzy :
Reimann C; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany. .; Department of Veterinary Medicine, Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, Königsweg 67, Building 21, 14163, Berlin, Germany. .
Brangsch J; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.; Department of Veterinary Medicine, Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, Königsweg 67, Building 21, 14163, Berlin, Germany.
Kaufmann JO; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.; Federal Institute for Materials Research and Testing (BAM), Division 1.5 Protein Analysis, Richard-Willstätter-Str. 11, 12489, Berlin, Germany.; Humboldt-Universität Berlin, Department of Chemistry, Brook-Taylor-Str. 2, 12489, Berlin, Germany.
Adams LC; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Onthank DC; Lantheus Medical Imaging, North Billerica, Massachusetts, 331 Treble Cove Road, USA.
Thöne-Reineke C; Department of Veterinary Medicine, Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, Königsweg 67, Building 21, 14163, Berlin, Germany.
Robinson SP; Lantheus Medical Imaging, North Billerica, Massachusetts, 331 Treble Cove Road, USA.
Hamm B; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Botnar RM; King's College London, School of Biomedical Engineering and Imaging Sciences, St Thomas' Hospital Westminster Bridge Road, London, SE1 7EH, United Kingdom.; Wellcome Trust/EPSRC Centre for Medical Engineering, King's College London, London, United Kingdom.; BHF Centre of Excellence, King's College London, London, United Kingdom.; Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile.
Makowski MR; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.; King's College London, School of Biomedical Engineering and Imaging Sciences, St Thomas' Hospital Westminster Bridge Road, London, SE1 7EH, United Kingdom.; BHF Centre of Excellence, King's College London, London, United Kingdom.
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Źródło :
Scientific reports [Sci Rep] 2019 Sep 25; Vol. 9 (1), pp. 13827. Date of Electronic Publication: 2019 Sep 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ferrosoferric Oxide/*administration & dosage
Gadolinium/*administration & dosage
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage
Magnetic Resonance Imaging/*methods
Plaque, Atherosclerotic/*drug therapy
Pravastatin/*administration & dosage
Animals ; Contrast Media ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Elastin/metabolism ; Feasibility Studies ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Male ; Mice ; Mice, Knockout, ApoE ; Nitric Oxide/metabolism ; Plaque, Atherosclerotic/diagnostic imaging ; Plaque, Atherosclerotic/metabolism ; Pravastatin/therapeutic use ; Sensitivity and Specificity
Czasopismo naukowe

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