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Wyszukujesz frazę ""Pravastatin"" wg kryterium: Temat


Tytuł:
Cholesterol partially rescues the inhibition effect of pravastatin on keratinocytes proliferation by regulating cell cycle relative proteins through AKT and ERK pathway.
Autorzy:
Li M; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Jin R; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Qi Y; General Department of Hyperbaric Oxygen, Affiliated Hefei Hospital of Anhui Medical University, Hefei, Anhui, China.
Zhou H; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Zhu T; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Liu L; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Gu Y; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Luan K; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Luo X; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Zhang S; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2020 Nov; Vol. 33 (6), pp. e14305. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology
Pravastatin*/pharmacology
Cell Cycle ; Cell Cycle Proteins ; Cell Proliferation ; Cholesterol ; Humans ; Keratinocytes/metabolism ; MAP Kinase Signaling System ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł:
Assessment of the Effect of Filgotinib on the Pharmacokinetics of Atorvastatin, Pravastatin, and Rosuvastatin in Healthy Adult Participants.
Autorzy:
Anderson, Kacey (AUTHOR)
Nelson, Cara H. (AUTHOR)
Gong, Qi (AUTHOR)
Alani, Muhsen (AUTHOR)
Tarnowski, Thomas (AUTHOR)
Othman, Ahmed A. (AUTHOR)
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Źródło:
Clinical Pharmacology in Drug Development. Feb2022, Vol. 11 Issue 2, p235-245. 11p.
Czasopismo naukowe
Tytuł:
Pravastatin attenuates the action of the ETS domain-containing protein ELK1 to prevent atherosclerosis in apolipoprotein E-knockout mice via modulation of extracellular signal-regulated kinase 1/2 signal pathway.
Autorzy:
Yan W; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Li D; Department of Medicine, Rhode Island Hospital and the Warren Alpert Medical School of Brown University, Providence, RI, USA.
Zhou X; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2017 Mar; Vol. 44 (3), pp. 344-352.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
MAP Kinase Signaling System/*drug effects
Oxidative Stress/*drug effects
Pravastatin/*therapeutic use
ets-Domain Protein Elk-1/*metabolism
Animals ; Apolipoproteins E/genetics ; Atherosclerosis/metabolism ; Disease Models, Animal ; Human Umbilical Vein Endothelial Cells ; Humans ; Hydrogen Peroxide/pharmacology ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Pravastatin/administration & dosage
Czasopismo naukowe
Tytuł:
The effect of statins on semen parameters in patients with hypercholesterolemia: A systematic review.
Autorzy:
Anagnostis P; Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Papanikolaou D; 2nd Department of Urology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Ioannidou PG; 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Bosdou JK; 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Mikhailidis DP; Department of Clinical Biochemistry, University College London Medical School, University College London (UCL, London, UK.
Hatzimouratidis K; 2nd Department of Urology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Goulis DG; Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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Źródło:
Andrology [Andrology] 2021 Sep; Vol. 9 (5), pp. 1504-1511. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*adverse effects
Hypercholesterolemia/*drug therapy
Pravastatin/*adverse effects
Semen/*drug effects
Simvastatin/*adverse effects
Adult ; Humans ; Male ; Middle Aged ; Prospective Studies ; Randomized Controlled Trials as Topic ; Sperm Motility/drug effects
Czasopismo naukowe
Tytuł:
Generalised decision curve analysis for explicit comparison of treatment effects.
Autorzy:
Hozo, Iztok
Djulbegovic, Benjamin
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Temat:
CARDIOVASCULAR disease prevention
STATINS (Cardiovascular agents)
DECISION trees
DRUG efficacy
PRAVASTATIN
CONFIDENCE intervals
ROSUVASTATIN
EVIDENCE-based medicine
INDIVIDUALIZED medicine
DESCRIPTIVE statistics
PREDICTION models
EVALUATION
Źródło:
Journal of Evaluation in Clinical Practice; Dec2023, Vol. 29 Issue 8, p1271-1278, 8p
Czasopismo naukowe
Tytuł:
Placental nitric oxide formation and endothelium‐dependent vasodilation underlie pravastatin effects against angiogenic imbalance, hypertension in pregnancy and intrauterine growth restriction.
Autorzy:
Chimini, Jessica Sabbatine
Possomato‐Vieira, Jose Sergio
da Silva, Maria Luiza Santos
Dias‐Junior, Carlos A.
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Źródło:
Basic & Clinical Pharmacology & Toxicology. Apr2019, Vol. 124 Issue 4, p385-393. 9p.
Czasopismo naukowe
Tytuł:
Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis.
Autorzy:
Kim JW; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Catholic University of Korea, Seoul, Korea.
Rhee CK
Kim TJ
Kim YH
Lee SH
Yoon HK
Kim SC
Lee SY
Kwon SS
Kim KH
Kim YK
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2010 Nov; Vol. 37 (11), pp. 1055-63.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury/*prevention & control
Anti-Inflammatory Agents/*therapeutic use
Bleomycin/*toxicity
Pravastatin/*therapeutic use
Pulmonary Fibrosis/*prevention & control
Acute Lung Injury/chemically induced ; Acute Lung Injury/metabolism ; Acute Lung Injury/pathology ; Animals ; Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/pharmacology ; Blotting, Western ; Bronchoalveolar Lavage Fluid/chemistry ; Connective Tissue Growth Factor/antagonists & inhibitors ; Connective Tissue Growth Factor/genetics ; Cyclin D1/antagonists & inhibitors ; Cyclin D1/genetics ; Disease Models, Animal ; Enzyme-Linked Immunosorbent Assay ; Female ; Gene Expression/drug effects ; Hydroxyproline/metabolism ; Mice ; Mice, Inbred C57BL ; Pravastatin/administration & dosage ; Pravastatin/pharmacology ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/metabolism ; Pulmonary Fibrosis/pathology ; Respiratory Distress Syndrome/prevention & control ; Reverse Transcriptase Polymerase Chain Reaction ; Transforming Growth Factor beta1/antagonists & inhibitors ; Transforming Growth Factor beta1/genetics ; rho GTP-Binding Proteins/antagonists & inhibitors ; rho GTP-Binding Proteins/genetics ; rhoA GTP-Binding Protein
Czasopismo naukowe
Tytuł:
Effect of R219K polymorphism of the ABCA1 gene on the lipid-lowering effect of pravastatin in Chinese patients with coronary heart disease.
Autorzy:
Li J; Department of Cardiac Care Unit, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Wang LF
Li ZQ
Pan W
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2009 May; Vol. 36 (5-6), pp. 567-70. Date of Electronic Publication: 2008 Oct 27.
Typ publikacji:
Controlled Clinical Trial; Journal Article
MeSH Terms:
ATP-Binding Cassette Transporters/*genetics
Coronary Disease/*drug therapy
Coronary Disease/*genetics
Polymorphism, Restriction Fragment Length/*physiology
Pravastatin/*therapeutic use
ATP Binding Cassette Transporter 1 ; Aged ; Amino Acid Substitution/genetics ; Arginine/genetics ; Asian People/genetics ; Coronary Disease/blood ; Female ; Gene Frequency ; Genotype ; Humans ; Hypolipidemic Agents/pharmacology ; Hypolipidemic Agents/therapeutic use ; Lipids/blood ; Lysine/genetics ; Male ; Middle Aged ; Pravastatin/pharmacology ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Pravastatin attenuates interferon-gamma action via modulation of STAT1 to prevent aortic atherosclerosis in apolipoprotein E-knockout mice.
Autorzy:
Zhou XX; Department of Cardiology, Shanghai Jiao Tong University Affiliated First People's Hospital, Shanghai, China.
Gao PJ
Sun BG
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2009 Apr; Vol. 36 (4), pp. 373-9. Date of Electronic Publication: 2008 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Apolipoproteins E/*genetics
Atherosclerosis/*prevention & control
Interferon-gamma/*physiology
Pravastatin/*pharmacology
STAT1 Transcription Factor/*metabolism
Animals ; Aorta/metabolism ; Aorta/pathology ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Down-Regulation/drug effects ; Drug Evaluation, Preclinical ; Gene Expression Regulation/drug effects ; Hypolipidemic Agents/pharmacology ; Hypolipidemic Agents/therapeutic use ; Interferon Regulatory Factor-1/metabolism ; Interferon-gamma/genetics ; Interferon-gamma/metabolism ; Lipids/blood ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Pravastatin/therapeutic use ; Suppressor of Cytokine Signaling 1 Protein ; Suppressor of Cytokine Signaling Proteins/metabolism
Czasopismo naukowe
Tytuł:
Pravastatin reduces microvascular basal lamina damage following focal cerebral ischemia and reperfusion.
Autorzy:
Trinkl A; Department of Neurology, Experimental Stroke Research, Ludwig-Maximillians University, Munich, Klinikum Grosshadern, Marchioninistr. 15, D-81377 Munich, Germany.
Vosko MR
Wunderlich N
Dichgans M
Hamann GF
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2006 Jul; Vol. 24 (2), pp. 520-6. Date of Electronic Publication: 2006 Jul 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cerebral Arterial Diseases/*drug therapy
Cerebral Arteries/*drug effects
Ischemic Attack, Transient/*drug therapy
Microcirculation/*drug effects
Pravastatin/*pharmacology
Reperfusion Injury/*drug therapy
Animals ; Basement Membrane/drug effects ; Basement Membrane/pathology ; Basement Membrane/physiopathology ; Biomarkers/metabolism ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/pathology ; Blood-Brain Barrier/physiopathology ; Cerebral Arterial Diseases/metabolism ; Cerebral Arterial Diseases/physiopathology ; Cerebral Arteries/pathology ; Cerebral Arteries/physiopathology ; Cerebral Infarction/drug therapy ; Cerebral Infarction/metabolism ; Cerebral Infarction/physiopathology ; Collagen Type IV/drug effects ; Collagen Type IV/metabolism ; Disease Models, Animal ; Down-Regulation/drug effects ; Down-Regulation/physiology ; Hemoglobins/metabolism ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Hyperemia/drug therapy ; Hyperemia/etiology ; Hyperemia/physiopathology ; Ischemic Attack, Transient/metabolism ; Ischemic Attack, Transient/physiopathology ; Male ; Microcirculation/pathology ; Microcirculation/physiopathology ; Pravastatin/therapeutic use ; Rats ; Rats, Wistar ; Reperfusion Injury/metabolism ; Reperfusion Injury/physiopathology
Czasopismo naukowe
Tytuł:
Pravastatin-induced lichenoid drug eruption.
Autorzy:
Pua VS; Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Scolyer RA
Barnetson RS
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Źródło:
The Australasian journal of dermatology [Australas J Dermatol] 2006 Feb; Vol. 47 (1), pp. 57-9.
Typ publikacji:
Case Reports; Journal Article; Review
MeSH Terms:
Drug Eruptions/*etiology
Drug Eruptions/*pathology
Lichenoid Eruptions/*chemically induced
Pravastatin/*adverse effects
Biopsy, Needle ; Coronary Disease/diagnosis ; Coronary Disease/drug therapy ; Female ; Follow-Up Studies ; Humans ; Immunohistochemistry ; Lichenoid Eruptions/pathology ; Middle Aged ; Pravastatin/therapeutic use ; Severity of Illness Index
Czasopismo naukowe
Tytuł:
Differential effects of metformin‐mediated BSEP repression on pravastatin and bile acid pharmacokinetics in humans: A randomized controlled trial.
Autorzy:
Metry, Melissa
Krug, Samuel A.
Karra, Vijaya Kumari
Kane, Maureen A.
Fink, Jeffrey C.
Shu, Yan
Wang, Hongbing
Polli, James E.
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Temat:
METFORMIN
BILE acids
RANDOMIZED controlled trials
PRAVASTATIN
BILE salts
PHARMACOKINETICS
Źródło:
CTS: Clinical & Translational Science; Oct2022, Vol. 15 Issue 10, p2468-2478, 11p
Czasopismo naukowe
Tytuł:
Renoprotective effects of atorvastatin compared with pravastatin on progression of early diabetic nephropathy.
Autorzy:
Takazakura, Akiko
Sakurai, Masaru
Bando, Yukihiro
Misu, Hirofumi
Takeshita, Yumie
Kita, Yuki
Shimizu, Akiko
Hayakawa, Tetsuo
Kato, Ken‐ichiro
Kaneko, Shuichi
Takamura, Toshinari
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Źródło:
Journal of Diabetes Investigation. May2015, Vol. 6 Issue 3, p346-353. 8p.
Czasopismo naukowe

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