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Tytuł :
Vaporized Hydrogen Peroxide and Ozone Gas Synergistically Reduce Prion Infectivity on Stainless Steel Wire.
Autorzy :
Hara H; Division of Molecular Neurobiology, Institute for Enzyme Research (KOSOKEN), Tokushima University, Tokushima 770-8503, Japan.
Chida J; Division of Molecular Neurobiology, Institute for Enzyme Research (KOSOKEN), Tokushima University, Tokushima 770-8503, Japan.
Pasiana AD; Division of Molecular Neurobiology, Institute for Enzyme Research (KOSOKEN), Tokushima University, Tokushima 770-8503, Japan.
Uchiyama K; Division of Molecular Neurobiology, Institute for Enzyme Research (KOSOKEN), Tokushima University, Tokushima 770-8503, Japan.
Kikuchi Y; Department of Nutrition, Faculty of Healthcare Sciences, Chiba Prefectural University of Health Sciences, Chiba 261-0014, Japan.
Naito T; RD Center, Miura Corporation, Ehime 799-2651, Japan.
Takahashi Y; RD Center, Miura Corporation, Ehime 799-2651, Japan.
Yamamura J; Environment & Clean Group, Strategy Development Department, Industrial Systems & General-Purpose Machinery Business Area, IHI Corporation, Tokyo 135-8710, Japan.
Kuromatsu H; Environment & Clean Group, Strategy Development Department, Industrial Systems & General-Purpose Machinery Business Area, IHI Corporation, Tokyo 135-8710, Japan.
Sakaguchi S; Division of Molecular Neurobiology, Institute for Enzyme Research (KOSOKEN), Tokushima University, Tokushima 770-8503, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 23; Vol. 22 (6). Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article
MeSH Terms :
Prions*
Stainless Steel*/chemistry
Hydrogen Peroxide/*chemistry
Ozone/*chemistry
Animals ; Brain/metabolism ; Brain/pathology ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Hydrogen Peroxide/pharmacology ; Mice ; Ozone/pharmacology ; PrPC Proteins/antagonists & inhibitors ; PrPC Proteins/chemistry ; Prion Diseases/etiology ; Prion Diseases/prevention & control
Czasopismo naukowe
Tytuł :
Successful transmission of the chronic wasting disease (CWD) agent to white-tailed deer by intravenous blood transfusion.
Autorzy :
Mammadova N; Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 1920 Dayton Avenue, Ames, IA 50010, USA; Oak Ridge Institute for Science and Education (ORISE), USA.
Cassmann E; Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 1920 Dayton Avenue, Ames, IA 50010, USA; Oak Ridge Institute for Science and Education (ORISE), USA.
Greenlee JJ; Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 1920 Dayton Avenue, Ames, IA 50010, USA. Electronic address: .
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Źródło :
Research in veterinary science [Res Vet Sci] 2020 Dec; Vol. 133, pp. 304-306. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article
MeSH Terms :
Deer*
Prions*/genetics
Prions*/metabolism
Prions*/pathogenicity
Blood Transfusion/*veterinary
Transfusion Reaction/*veterinary
Wasting Disease, Chronic/*transmission
Animals ; Female ; Genotype ; Male ; Prion Proteins/metabolism ; Wasting Disease, Chronic/genetics ; Wasting Disease, Chronic/metabolism
Czasopismo naukowe
Tytuł :
Dangerous Stops: Nonsense Mutations Can Dramatically Increase Frequency of Prion Conversion.
Autorzy :
Dergalev AA; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, 119071 Moscow, Russia.
Urakov VN; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, 119071 Moscow, Russia.
Agaphonov MO; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, 119071 Moscow, Russia.
Alexandrov AI; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, 119071 Moscow, Russia.
Kushnirov VV; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, 119071 Moscow, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 03; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Codon, Nonsense*
Amyloid/*metabolism
Prions/*genetics
Prions/*metabolism
Amyloidosis/genetics ; Amyloidosis/metabolism ; Amyloidosis/pathology ; Fungal Proteins/chemistry ; Fungal Proteins/genetics ; Fungal Proteins/metabolism ; Mass Spectrometry ; Prions/chemistry ; Protein Aggregates ; RNA Splicing
Czasopismo naukowe
Tytuł :
RNA as the stone guest of protein aggregation.
Autorzy :
Louka A; UK Dementia Research Institute at the Maurice Wohl Institute of King's College London, London SE5 9RT, UK.
Zacco E; Center for Human Technologies, Central RNA laboratory, Istituto Italiano di Tecnologia, Genova 16152, Italy.
Temussi PA; UK Dementia Research Institute at the Maurice Wohl Institute of King's College London, London SE5 9RT, UK.; University 'Federico II'' Napoli, via Cynthia, Napoli 80100, Italy.
Tartaglia GG; Center for Human Technologies, Central RNA laboratory, Istituto Italiano di Tecnologia, Genova 16152, Italy.; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona 08003, Spain and ICREA, 23 Passeig Lluıs Companys, Barcelona 08010, Spain.; Charles Darwin department of Biology and Biotechnology, Sapienza University of Rome, Piazzale A. Moro 5, Rome 00185, Italy.
Pastore A; UK Dementia Research Institute at the Maurice Wohl Institute of King's College London, London SE5 9RT, UK.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Dec 02; Vol. 48 (21), pp. 11880-11889.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Amyotrophic Lateral Sclerosis/*genetics
DNA-Binding Proteins/*genetics
Prions/*genetics
RNA/*genetics
RNA-Binding Protein FUS/*genetics
RNA-Binding Proteins/*genetics
TATA-Binding Protein Associated Factors/*genetics
Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Binding Sites ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/metabolism ; Gene Expression ; Humans ; Models, Molecular ; Prions/chemistry ; Prions/metabolism ; Protein Aggregates ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; RNA/chemistry ; RNA/metabolism ; RNA-Binding Protein FUS/chemistry ; RNA-Binding Protein FUS/metabolism ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/metabolism ; TATA-Binding Protein Associated Factors/chemistry ; TATA-Binding Protein Associated Factors/metabolism
Czasopismo naukowe
Tytuł :
Epilepsy and prion diseases: A narrative review.
Autorzy :
Mbizvo GK; Cognitive Function Clinic, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom. Electronic address: .
Ziso B; Cognitive Function Clinic, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.
Larner AJ; Cognitive Function Clinic, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.
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Źródło :
Epilepsy & behavior : E&B [Epilepsy Behav] 2021 Feb; Vol. 115, pp. 107630. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Creutzfeldt-Jakob Syndrome*
Epilepsy*
Prion Diseases*/complications
Prion Diseases*/diagnosis
Prions*/genetics
Humans ; Seizures
Czasopismo naukowe
Tytuł :
Short and sweet: How glycans impact prion conversion, cofactor interactions, and cross-species transmission.
Autorzy :
Aguilar-Calvo P; Department of Pathology, University of California, San Diego, La Jolla, California, United States of America.
Callender JA; Department of Pathology, University of California, San Diego, La Jolla, California, United States of America.
Sigurdson CJ; Department of Pathology, University of California, San Diego, La Jolla, California, United States of America.; Department of Medicine, University of California, San Diego, La Jolla, California, United States of America.; Department of Pathology, Microbiology, and Immunology, University of California, Davis, Davis, California, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Jan 14; Vol. 17 (1), pp. e1009123. Date of Electronic Publication: 2021 Jan 14 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Amyloid/*metabolism
Polysaccharides/*metabolism
PrPC Proteins/*metabolism
Prion Diseases/*transmission
Prions/*metabolism
Amyloid/chemistry ; Animals ; Polysaccharides/chemistry ; Prion Diseases/metabolism ; Prions/chemistry ; Species Specificity
Czasopismo naukowe
Tytuł :
Highly infectious prions are not directly neurotoxic.
Autorzy :
Benilova I; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Reilly M; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Terry C; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Wenborn A; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Schmidt C; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Marinho AT; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Risse E; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Al-Doujaily H; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Wiggins De Oliveira M; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Sandberg MK; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Wadsworth JDF; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Jat PS; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom.
Collinge J; Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 22; Vol. 117 (38), pp. 23815-23822. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurotoxins*/isolation & purification
Neurotoxins*/metabolism
Neurotoxins*/toxicity
Prion Diseases*/metabolism
Prion Diseases*/physiopathology
Prions*/isolation & purification
Prions*/metabolism
Prions*/pathogenicity
Animals ; Brain/cytology ; Brain/drug effects ; Brain Chemistry ; Disease Models, Animal ; Mice ; Neurons/drug effects
Czasopismo naukowe
Tytuł :
Prion-like proteins as epigenetic devices of stress adaptation.
Autorzy :
Oamen HP; School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK.
Lau Y; School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK.
Caudron F; School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2020 Nov 01; Vol. 396 (1), pp. 112262. Date of Electronic Publication: 2020 Sep 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Epigenesis, Genetic*
Carrier Proteins/*genetics
Molecular Chaperones/*genetics
Prions/*genetics
RNA-Binding Proteins/*genetics
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*genetics
Transcription Factors/*genetics
Adaptation, Physiological/genetics ; Animals ; Carrier Proteins/chemistry ; Carrier Proteins/metabolism ; GPI-Linked Proteins/chemistry ; GPI-Linked Proteins/genetics ; GPI-Linked Proteins/metabolism ; Genotype ; Humans ; Molecular Chaperones/metabolism ; Phenotype ; Prions/chemistry ; Prions/metabolism ; Protein Conformation ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/metabolism ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/metabolism ; Stress, Physiological ; Transcription Factors/chemistry ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
The Effects of Immune System Modulation on Prion Disease Susceptibility and Pathogenesis.
Autorzy :
Mabbott NA; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Bradford BM; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Pal R; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Young R; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Donaldson DS; The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 02; Vol. 21 (19). Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Brain/*immunology
Immune System/*immunology
Prion Diseases/*immunology
Prions/*immunology
Aging/immunology ; Aging/pathology ; Brain/metabolism ; Disease Susceptibility ; Humans ; Immune System/metabolism ; Immunomodulation/genetics ; Prion Diseases/genetics ; Prion Diseases/pathology ; Prions/genetics
Czasopismo naukowe
Tytuł :
All-atom simulation of the HET-s prion replication.
Autorzy :
Terruzzi L; Sibylla Biotech SRL, Verona, Italy.; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Povo, Trento, Italy.
Spagnolli G; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Povo, Trento, Italy.; Dulbecco Telethon Institute, University of Trento, Povo, Trento, Italy.
Boldrini A; Sibylla Biotech SRL, Verona, Italy.; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Povo, Trento, Italy.
Requena JR; CIMUS Biomedical Research Institute & Department of Medical Sciences, University of Santiago de Compostela-IDIS, Spain.
Biasini E; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Povo, Trento, Italy.; Dulbecco Telethon Institute, University of Trento, Povo, Trento, Italy.
Faccioli P; Department of Physics, University of Trento, Povo, Trento, Italy.; INFN-TIFPA, University of Trento, Povo, Trento, Italy.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Sep 18; Vol. 16 (9), pp. e1007922. Date of Electronic Publication: 2020 Sep 18 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fungal Proteins*/chemistry
Fungal Proteins*/metabolism
Molecular Dynamics Simulation*
Prions*/chemistry
Prions*/metabolism
Algorithms ; Computational Biology ; Protein Conformation ; Protein Folding
Czasopismo naukowe
Tytuł :
Mechanisms for Curing Yeast Prions.
Autorzy :
Greene LE; Laboratory of Cell Biology, National Heart Lung Blood Institute National Institutes of Health, Bethesda, MD 20892, USA.
Saba F; Laboratory of Cell Biology, National Heart Lung Blood Institute National Institutes of Health, Bethesda, MD 20892, USA.
Silberman RE; Laboratory of Cell Biology, National Heart Lung Blood Institute National Institutes of Health, Bethesda, MD 20892, USA.; Koch Institute for Integrative Cancer Research, Depart Biol., Howard Hughes Medical Institute, MIT Cambridge, MA 02139, USA.
Zhao X; Laboratory of Cell Biology, National Heart Lung Blood Institute National Institutes of Health, Bethesda, MD 20892, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 07; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Prions/*genetics
Prions/*metabolism
Saccharomyces cerevisiae/*metabolism
Heat-Shock Proteins/metabolism ; Peptide Termination Factors/metabolism ; Prions/pathogenicity ; Proteolysis ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł :
Phase Separation as a Molecular Thermosensor.
Autorzy :
Li C; Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Fang X; Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address: .
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Źródło :
Developmental cell [Dev Cell] 2020 Oct 26; Vol. 55 (2), pp. 118-119.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Arabidopsis*
Arabidopsis Proteins*
Prions*
Temperature ; Transcription Factors
Czasopismo naukowe
Tytuł :
Zinc and Copper Ions Differentially Regulate Prion-Like Phase Separation Dynamics of Pan-Virus Nucleocapsid Biomolecular Condensates.
Autorzy :
Monette A; Lady Davis Institute at the Jewish General Hospital, Montréal, QC H3T 1E2, Canada.
Mouland AJ; Lady Davis Institute at the Jewish General Hospital, Montréal, QC H3T 1E2, Canada.; Department of Medicine, McGill University, Montréal, QC H4A 3J1, Canada.
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Źródło :
Viruses [Viruses] 2020 Oct 18; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Copper/*metabolism
Nucleocapsid/*metabolism
Nucleocapsid Proteins/*metabolism
Prions/*metabolism
Zinc/*metabolism
Computational Biology ; Meta-Analysis as Topic ; Molecular Dynamics Simulation ; Neurodegenerative Diseases/virology ; Nucleocapsid/genetics ; Nucleocapsid Proteins/genetics ; Prions/genetics ; Protein Domains ; Viral Proteins/genetics ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł :
A Prion-based Thermosensor in Plants.
Autorzy :
Wilkinson EG; Center for Science and Engineering Living Systems (CSELS), Washington University, St. Louis, MO 63130, USA; Center for Engineering Mechanobiology, Washington University, St. Louis, MO 63130, USA; Department of Biology, Duke University, Durham, NC 27708, USA.
Strader LC; Center for Science and Engineering Living Systems (CSELS), Washington University, St. Louis, MO 63130, USA; Center for Engineering Mechanobiology, Washington University, St. Louis, MO 63130, USA; Department of Biology, Duke University, Durham, NC 27708, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Oct 15; Vol. 80 (2), pp. 181-182.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Arabidopsis*/genetics
Arabidopsis Proteins*/genetics
Prions*/genetics
Protein Domains ; Temperature ; Transcription Factors
Czasopismo naukowe
Tytuł :
The Effects of Divalent Cation-Chelated Prion Fibrils on the Immune Response of EOC 13.31 Microglia Cells.
Autorzy :
Jen HI; Department of Biomedical Sciences, National Chung Cheng University, 168 University Road, Min-Hsiung Chia-Yi 62102, Taiwan.
Lin ZY; Department of Biomedical Sciences, National Chung Cheng University, 168 University Road, Min-Hsiung Chia-Yi 62102, Taiwan.
Guo JX; Department of Biomedical Sciences, National Chung Cheng University, 168 University Road, Min-Hsiung Chia-Yi 62102, Taiwan.
Lee CI; Department of Biomedical Sciences, National Chung Cheng University, 168 University Road, Min-Hsiung Chia-Yi 62102, Taiwan.; Center for Nano Bio-Detections, National Chung Cheng University, Min-Hsiung Chia-Yi 62102, Taiwan.; Center for Innovative Research on Aging Society (CIRAS), National Chung Cheng University, Min-Hsiung Chia-Yi 62102, Taiwan.
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Źródło :
Cells [Cells] 2020 Oct 13; Vol. 9 (10). Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cations, Divalent/*pharmacology
Chelating Agents/*pharmacology
Microglia/*immunology
Prions/*metabolism
Animals ; Cell Line ; Cytokines/metabolism ; Inflammation Mediators/metabolism ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Mice ; Microglia/drug effects ; NF-KappaB Inhibitor alpha/genetics ; NF-KappaB Inhibitor alpha/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Peptides/chemistry ; Prions/chemistry ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reactive Oxygen Species/metabolism ; Repetitive Sequences, Amino Acid
Czasopismo naukowe
Tytuł :
Prion biology: implications for Alzheimer's disease therapeutics.
Autorzy :
Condello C; Institute for Neurodegenerative Diseases, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
DeGrado WF; Institute for Neurodegenerative Diseases, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA.
Prusiner SB; Institute for Neurodegenerative Diseases, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: .
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Źródło :
The Lancet. Neurology [Lancet Neurol] 2020 Oct; Vol. 19 (10), pp. 802-803. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Alzheimer Disease*
Prions*
Amyloid beta-Peptides ; Humans
Czasopismo naukowe
Tytuł :
Prions and prion diseases: Insights from the eye.
Autorzy :
Singh N; Departments of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA. Electronic address: .
Chaudhary S; Departments of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
Ashok A; Departments of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
Lindner E; Department of Ophthalmology, Medical University of Graz, Auenbruggerplatz 4, 8036, Graz, Austria.
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Źródło :
Experimental eye research [Exp Eye Res] 2020 Oct; Vol. 199, pp. 108200. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Gene Expression Regulation*
Anterior Eye Segment/*metabolism
Prions/*genetics
Animals ; Anterior Eye Segment/pathology ; Homeostasis ; Humans ; Prion Diseases/genetics ; Prion Diseases/metabolism ; Prion Diseases/pathology ; Prions/biosynthesis ; Protein Conformation
Czasopismo naukowe
Tytuł :
RNA-binding and prion domains: the Yin and Yang of phase separation.
Autorzy :
Gotor NL; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr Aiguader 88, 08003 Barcelona, Spain and Universitat Pompeu Fabra (UPF), 08003 Barcelona, Spain.
Armaos A; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr Aiguader 88, 08003 Barcelona, Spain and Universitat Pompeu Fabra (UPF), 08003 Barcelona, Spain.; Center for Human Technologies, Istituto Italiano di Tecnologia, RNA System Biology Lab, Via Enrico Melen 83, 16152 Genoa, Italy.
Calloni G; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, 60438, Germany.; Institute of Biophysical Chemistry, Goethe University Frankfurt, Frankfurt am Main,60438, Germany.
Torrent Burgas M; Systems Biology of Infection Lab, Department of Biochemistry and Molecular Biology, Biosciences Faculty, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, Spain.
Vabulas RM; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, 60438, Germany.; Institute of Biophysical Chemistry, Goethe University Frankfurt, Frankfurt am Main,60438, Germany.; Charité - Universitätsmedizin Berlin, Institute of Biochemistry, 10117 Berlin, Germany.
De Groot NS; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr Aiguader 88, 08003 Barcelona, Spain and Universitat Pompeu Fabra (UPF), 08003 Barcelona, Spain.
Tartaglia GG; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr Aiguader 88, 08003 Barcelona, Spain and Universitat Pompeu Fabra (UPF), 08003 Barcelona, Spain.; Center for Human Technologies, Istituto Italiano di Tecnologia, RNA System Biology Lab, Via Enrico Melen 83, 16152 Genoa, Italy.; Institucio Catalana de Recerca i Estudis Avançats (ICREA), 23 Passeig Lluis Companys, 08010 Barcelona, Spain.; Department of Biology and Biotechnology, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Sep 25; Vol. 48 (17), pp. 9491-9504.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Phase Transition*
Prions/*metabolism
Proteins/*metabolism
RNA/*metabolism
Binding Sites ; Fluorescence Recovery After Photobleaching ; Humans ; Poly(A)-Binding Proteins/chemistry ; Poly(A)-Binding Proteins/genetics ; Poly(A)-Binding Proteins/metabolism ; Prions/chemistry ; Protein Domains ; Proteins/chemistry ; Proteome ; RNA/chemistry ; RNA Recognition Motif Proteins/chemistry ; RNA Recognition Motif Proteins/metabolism ; RNA-Binding Motifs ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł :
[Relationship between Type I and Type II Template Processes: Amyloids and Genome Stability].
Autorzy :
Andreychuk YV; Vavilov Institute of General Genetics, St. Petersburg Branch, Russian Academy of Sciences, St. Petersburg, 199034 Russia.; .
Zadorsky SP; Vavilov Institute of General Genetics, St. Petersburg Branch, Russian Academy of Sciences, St. Petersburg, 199034 Russia.; St. Petersburg State University, St. Petersburg, 199034 Russia.
Zhuk AS; IТМО University, St. Petersburg, 197101 Russia.
Stepchenkova EI; Vavilov Institute of General Genetics, St. Petersburg Branch, Russian Academy of Sciences, St. Petersburg, 199034 Russia.; St. Petersburg State University, St. Petersburg, 199034 Russia.
Inge-Vechtomov SG; Vavilov Institute of General Genetics, St. Petersburg Branch, Russian Academy of Sciences, St. Petersburg, 199034 Russia.; St. Petersburg State University, St. Petersburg, 199034 Russia.
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Źródło :
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2020 Sep-Oct; Vol. 54 (5), pp. 750-775.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Amyloid*/genetics
Genomic Instability*
Prions*/genetics
Alzheimer Disease/genetics ; Down Syndrome/genetics ; Humans ; Neoplasms/genetics ; Parkinson Disease/genetics ; RNA
Czasopismo naukowe

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