Temat: "Prions" - OpacWWW - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: Foiling deadly prions.
Autorzy:: Wadman M; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2024 Mar 22; Vol. 383 (6689), pp. 1284-1289. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:: Wiadomości
MeSH Terms:: Prion Diseases*/genetics
Prion Diseases*/prevention & control
Prions*/antagonists & inhibitors
Prions*/genetics
Humans ; Mutation ; Zinc Fingers

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Skocz do pozycji: 2.

Tytuł:: Sequestrase chaperones protect against oxidative stress-induced protein aggregation and [PSI+] prion formation.
Autorzy:: Carter Z; Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, United Kingdom.
Creamer D; Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, United Kingdom.
Kouvidi A; Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, United Kingdom.
Grant CM; Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, United Kingdom.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2024 Feb 29; Vol. 20 (2), pp. e1011194. Date of Electronic Publication: 2024 Feb 29 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Prions*/genetics
Prions*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Protein Aggregates/genetics ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Oxidative Stress/genetics ; Amyloid/metabolism ; Oxidants/pharmacology ; Oxidants/metabolism ; Peptide Termination Factors/genetics ; Peptide Termination Factors/metabolism

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Skocz do pozycji: 3.

Tytuł:: Single nucleotide polymorphisms (SNPs) in the open reading frame (ORF) of prion protein gene (PRNP) in Nigerian livestock species.
Autorzy:: Adeola AC; State Key Laboratory of Genetic Resources and Evolution & Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China. .; Sino-Africa Joint Research Center, Chinese Academy of Sciences, Kunming, China. .
Bello SF; Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, 510642, Guangzhou, China.
Abdussamad AM; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, Bayero University, Kano, Nigeria.
Adedokun RAM; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Olaogun SC; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Abdullahi N; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, Bayero University, Kano, Nigeria.
Mark AI; Ministry of Agriculture and Rural Development, Secretariat, Ibadan, Nigeria.
Onoja AB; Department of Virology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Sanke OJ; Taraba State Ministry of Agriculture and Natural Resources, Jalingo, Nigeria.
Mangbon GF; Division of Veterinary Office, Serti, Nigeria.
Ibrahim J; Department of Veterinary Surgery and Theriogenology, College of Veterinary Medicine, University of Agriculture Makurdi, Makurdi, Nigeria.
Dawuda PM; Department of Animal Science, Faculty of Agriculture, National University of Lesotho, Maseru, South Africa.
Salako AE; Department of Animal Science, Faculty of Agriculture, University of Ibadan, Ibadan, Nigeria.
Kdidi S; Livestock and Wildlife Laboratory, Institut des Régions Arides, Université de Gabes, Route El Djorf, Km 22.5, 4119, Medenine, Tunisia.
Yahyaoui MH; Livestock and Wildlife Laboratory, Institut des Régions Arides, Université de Gabes, Route El Djorf, Km 22.5, 4119, Medenine, Tunisia.; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2024 Feb 14; Vol. 25 (1), pp. 177. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:: Journal Article
MeSH Terms:: Prions*/genetics
Prions*/metabolism
Prion Diseases*/genetics
Prion Diseases*/veterinary
Scrapie*/genetics
Animals ; Horses/genetics ; Sheep/genetics ; Dogs ; Prion Proteins/genetics ; Polymorphism, Single Nucleotide ; Livestock/genetics ; Open Reading Frames ; Phylogeny ; Camelus/genetics ; Goats/genetics ; Goats/metabolism

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Skocz do pozycji: 4.

Tytuł:: Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas.
Autorzy:: Boccacino JM; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Dos Santos Peixoto R; Department of Automation and Systems, Technological Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Fernandes CFL; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Cangiano G; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Sola PR; Cellular and Molecular Biology Laboratory (LIM 15), Department of Neurology, Faculdade de Medicina (FMUSP), University of Sao Paulo, Sao Paulo, Brazil.
Coelho BP; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Prado MB; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Melo-Escobar MI; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
de Sousa BP; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Ayyadhury S; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Bader GD; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.
Shinjo SMO; Cellular and Molecular Biology Laboratory (LIM 15), Department of Neurology, Faculdade de Medicina (FMUSP), University of Sao Paulo, Sao Paulo, Brazil.
Marie SKN; Cellular and Molecular Biology Laboratory (LIM 15), Department of Neurology, Faculdade de Medicina (FMUSP), University of Sao Paulo, Sao Paulo, Brazil.
da Rocha EL; Department of Microbiology, Immunology, and Parasitology, Biological Sciences Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil. .
Lopes MH; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2024 Feb 13; Vol. 24 (1), pp. 199. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:: Journal Article
MeSH Terms:: Glioblastoma*/genetics
Glioblastoma*/pathology
Prions*/genetics
Prions*/metabolism
Humans ; Gene Expression ; Gene Expression Profiling ; Prion Proteins/genetics ; Prion Proteins/metabolism ; rab GTP-Binding Proteins/genetics ; Synaptophysin/metabolism

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Skocz do pozycji: 5.

Tytuł:: Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease.
Autorzy:: Walsh DJ; Department of Biochemistry and Cell Biology Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
Rees JR; Department of Epidemiology Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.; Department of Community and Family Medicine Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
Mehra S; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
Bourkas MEC; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Kaczmarczyk L; Wallenberg Center for Molecular Medicine, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Stuart E; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Jackson WS; Wallenberg Center for Molecular Medicine, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Watts JC; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Supattapone S; Department of Biochemistry and Cell Biology Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.; Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2024 Apr 01; Vol. 20 (4), pp. e1012087. Date of Electronic Publication: 2024 Apr 01 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Prions*/metabolism
Prion Diseases*/drug therapy
Prion Diseases*/genetics
Prion Diseases*/metabolism
Creutzfeldt-Jakob Syndrome*/drug therapy
Creutzfeldt-Jakob Syndrome*/genetics
Creutzfeldt-Jakob Syndrome*/metabolism
Animals ; Mice ; Prion Proteins/genetics ; Prion Proteins/metabolism ; Brain/pathology ; Arvicolinae/metabolism

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Skocz do pozycji: 6.

Tytuł:: Mapping of Prion Structures in the Yeast Rnq1.
Autorzy:: Galliamov AA; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Moscow 119071, Russia.
Malukhina AD; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Moscow 119071, Russia.; Department of Biology, Moscow State University, Moscow 119991, Russia.
Kushnirov VV; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Moscow 119071, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 17; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 17.
Typ publikacji:: Journal Article
MeSH Terms:: Prions*/metabolism
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism

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Skocz do pozycji: 7.

Tytuł:: Detection of prions in matching post-mortem skin and cerebrospinal fluid samples using second-generation real-time quaking-induced conversion assay.
Autorzy:: Baranová S; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Moško T; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Brůžová M; Department of Pathology and Molecular Medicine, Third Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic.
Haldiman T; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Kim C; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Safar JG; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Matěj R; Department of Pathology and Molecular Medicine, Third Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic.; Department of Pathology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic.; Department of Pathology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Holada K; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University, Prague, Czech Republic. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 15; Vol. 14 (1), pp. 6294. Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Prions*/metabolism
Prion Diseases*/diagnosis
Creutzfeldt-Jakob Syndrome*/diagnosis
Creutzfeldt-Jakob Syndrome*/cerebrospinal fluid
Humans ; Skin/metabolism ; Prion Proteins ; Biological Assay

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Skocz do pozycji: 8.

Tytuł:: Detection limitations of prion seeding activities in blood samples from patients with sporadic prion disease.
Autorzy:: Nonaka T; Division of Cellular and Molecular Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, 852-8501, Japan.
Iwasaki Y; Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Nagakute City, 480-1195, Japan.
Horiuchi H; Laboratory of Immunobiology, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima City, Japan.
Satoh K; Department of Health Sciences, Unit of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, Japan. .; Pokaż więcej
Źródło:: BMC neurology [BMC Neurol] 2024 Mar 11; Vol. 24 (1), pp. 92. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:: Journal Article
MeSH Terms:: Prions*/metabolism
Prion Diseases*/diagnosis
Prion Diseases*/metabolism
Creutzfeldt-Jakob Syndrome*/diagnosis
Humans ; Prion Proteins ; Brain/metabolism ; Plasma/metabolism

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Skocz do pozycji: 9.

Tytuł:: New Light on Prions: Putative Role of PrP in Pathophysiology of Mood Disorders.
Autorzy:: Chrobak AA; Department of Adult Psychiatry, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.
Pańczyszyn-Trzewik P; Department of Human Physiology, Institute of Medical Sciences, Medical College of Rzeszow University, Kopisto 2a, 35-959 Rzeszow, Poland.
Król P; Department of Adult Psychiatry, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.
Pawelec-Bąk M; Department of Affective Disorders, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.
Dudek D; Department of Adult Psychiatry, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.
Siwek M; Department of Affective Disorders, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 04; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Creutzfeldt-Jakob Syndrome*/metabolism
Prions*/metabolism
PrPC Proteins*
Humans ; Mood Disorders ; Neuronal Plasticity ; Synaptic Transmission

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Skocz do pozycji: 10.

Tytuł:: N-Glycosylation as a Modulator of Protein Conformation and Assembly in Disease.
Autorzy:: Pasala C; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Sharma S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Roychowdhury T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Moroni E; The Institute of Chemical Sciences and Technologies (SCITEC), Italian National Research Council (CNR), 20131 Milano, Italy.
Colombo G; The Institute of Chemical Sciences and Technologies (SCITEC), Italian National Research Council (CNR), 20131 Milano, Italy.; Department of Chemistry, University of Pavia, 27100 Pavia, Italy.
Chiosis G; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2024 Feb 27; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Protein Processing, Post-Translational*
Prions*/metabolism
Glycosylation ; Polysaccharides/chemistry ; Protein Conformation

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Skocz do pozycji: 11.

Tytuł:: Viroids, Satellite RNAs and Prions: Folding of Nucleic Acids and Misfolding of Proteins.
Autorzy:: Steger G; Institut für Physikalische Biologie, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, 40204 Düsseldorf, Germany.
Riesner D; Institut für Physikalische Biologie, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, 40204 Düsseldorf, Germany.
Prusiner SB; Institute for Neurodegenerative Diseases, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA 94158, USA.; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2024 Feb 26; Vol. 16 (3). Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:: Journal Article
MeSH Terms:: Viroids*/genetics
Viroids*/metabolism
Prions*
Nucleic Acids*
Animals ; RNA, Satellite/genetics ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Plant Diseases

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Skocz do pozycji: 12.

Tytuł:: The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease.
Autorzy:: Ward A; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Jessop F; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Faris R; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America.
Hollister J; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Shoup D; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Race B; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Bosio CM; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Priola SA; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Feb 23; Vol. 19 (2), pp. e0298095. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Neurodegenerative Diseases*
Prion Diseases*/genetics
Prions*
Mice ; Animals ; Mitophagy ; Protein Kinases/genetics ; Protein Kinases/metabolism ; Reactive Oxygen Species/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism

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Skocz do pozycji: 13.

Tytuł:: Temporal serum neurofilament light chain concentrations in sheep inoculated with the agent of classical scrapie.
Autorzy:: Brown Q; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America.; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Christensen, Ames, United States of America.
Nicholson E; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.
Wang C; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America.
Greenlee J; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.
Seger H; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America.
Veneziano S; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.
Cassmann E; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Feb 23; Vol. 19 (2), pp. e0299038. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Scrapie*/genetics
Prions*/metabolism
Humans ; Sheep ; Animals ; PrPSc Proteins/metabolism ; Intermediate Filaments/metabolism ; Brain/metabolism ; Biomarkers

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Skocz do pozycji: 14.

Tytuł:: Detection of prions from spiked and free-ranging carnivore feces.
Autorzy:: Inzalaco HN; Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, University of Wisconsin, Madison, Madison, WI, 53706, USA. .
Brandell EE; Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, University of Wisconsin, Madison, Madison, WI, 53706, USA.
Wilson SP; Nebraska Game and Parks Commission, 2200 N 33rd St., P.O. Box 30370, Lincoln, NE, 68503, USA.
Hunsaker M; Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, University of Wisconsin, Madison, Madison, WI, 53706, USA.
Stahler DR; Yellowstone Center for Resources, Yellowstone National Park, WY, 82190, USA.
Woelfel K; Wild and Free Wildlife Rehabilitation Program, 27264 MN-18, Garrison, MN, 56450, USA.
Walsh DP; U.S. Geological Survey, Montana Cooperative Wildlife Research Unit, University of Montana, Missoula, MT, USA.
Nordeen T; Nebraska Game and Parks Commission, 2200 N 33rd St., P.O. Box 30370, Lincoln, NE, 68503, USA.
Storm DJ; Wisconsin Department of Natural Resources, Eau Claire, WI, 54701, USA.
Lichtenberg SS; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN, 55108, USA.
Turner WC; U.S. Geological Survey, Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, University of Wisconsin - Madison, Madison, WI, 53706, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 15; Vol. 14 (1), pp. 3804. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:: Journal Article
MeSH Terms:: Prions*
Neurodegenerative Diseases*
Wasting Disease, Chronic*/diagnosis
Wasting Disease, Chronic*/epidemiology
Deer*
Coyotes*
Animals ; Feces

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Skocz do pozycji: 15.

Tytuł:: The role of α-synuclein prion strains in Parkinson's disease and multiple system atrophy.
Autorzy:: Khedmatgozar CR; Department of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, United States of America.
Holec SAM; Department of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, United States of America.
Woerman AL; Department of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2024 Jan 25; Vol. 20 (1), pp. e1011920. Date of Electronic Publication: 2024 Jan 25 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Parkinson Disease*
Multiple System Atrophy*
Prions*
Humans ; alpha-Synuclein

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Skocz do pozycji: 16.

Tytuł:: Nuclear-import receptors as gatekeepers of pathological phase transitions in ALS/FTD.
Autorzy:: Khalil B; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, U.S.A.
Linsenmeier M; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, U.S.A.
Smith CL; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, U.S.A.; Mayo Clinic Graduate School of Biomedical Sciences, Neuroscience Track, Mayo Clinic, Jacksonville, FL, 32224, U.S.A.
Shorter J; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, U.S.A.. .
Rossoll W; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, U.S.A.. .; Pokaż więcej
Źródło:: Molecular neurodegeneration [Mol Neurodegener] 2024 Jan 22; Vol. 19 (1), pp. 8. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Frontotemporal Dementia*
Amyotrophic Lateral Sclerosis*
Prions*
Humans ; Active Transport, Cell Nucleus ; DNA-Binding Proteins

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Skocz do pozycji: 17.

Tytuł:: In Vitro and In Vivo Evidence towards Fibronectin's Protective Effects against Prion Infection.
Autorzy:: Garza MC; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.; Department of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Kang SG; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.; Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Kim C; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.; Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Monleón E; Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Departamento de Anatomía e Histología Humana, Universidad de Zaragoza, IA2, IIS Aragón, 50013 Zaragoza, Spain.
van der Merwe J; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.; Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.
Kramer DA; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 1C9, Canada.
Fahlman R; Department of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Sim VL; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.; Department of Medicine, University of Alberta, Edmonton, AB T6G 2G3, Canada.; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Aiken J; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB T6G 2E1, Canada.; Department of Agriculture, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 1C9, Canada.
McKenzie D; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.; Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada.; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Cortez LM; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.; Department of Medicine, University of Alberta, Edmonton, AB T6G 2G3, Canada.
Wille H; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, AB T6G 2M8, Canada.; Department of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB T6G 2E1, Canada.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 15; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:: Journal Article
MeSH Terms:: Fibronectins*/therapeutic use
Prion Diseases*/drug therapy
Prion Diseases*/prevention & control
Prions*/metabolism
Scrapie*/metabolism
Animals ; Humans ; Cell Line ; Sheep

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Skocz do pozycji: 18.

Tytuł:: Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model.
Autorzy:: Williams K; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Foliaki ST; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Race B; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Smith A; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Thomas T; Rocky Mountain Veterinary Branch, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Groveman BR; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA.
Haigh CL; Laboratory of Neurological Infections and Immunity, National Institute of Allergy and Infectious Diseases, Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, 903 South 4Th Street, Hamilton, MT, 59840, USA. .; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2023 Dec 05; Vol. 14 (1), pp. 348. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:: Journal Article
MeSH Terms:: Creutzfeldt-Jakob Syndrome*/therapy
Neurodegenerative Diseases*
Prions*
Prion Diseases*
Animals ; Humans ; Organoids
SCR Disease Name:: Creutzfeldt-Jakob Disease, Sporadic

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Skocz do pozycji: 19.

Tytuł:: α-Synuclein emulsifies TDP-43 prion-like domain-RNA liquid droplets to promote heterotypic amyloid fibrils.
Autorzy:: Dhakal S; Department of Chemistry and Biochemistry, School of Mathematics and Natural Sciences, University of Southern Mississippi, Hattiesburg, MS, 39406, USA.; Center for Molecular and Cellular Biosciences, University of Southern Mississippi, Hattiesburg, MS, 39406, USA.
Mondal M; Department of Chemistry and Biochemistry, School of Mathematics and Natural Sciences, University of Southern Mississippi, Hattiesburg, MS, 39406, USA.; Center for Molecular and Cellular Biosciences, University of Southern Mississippi, Hattiesburg, MS, 39406, USA.
Mirzazadeh A; Department of Chemistry and Biochemistry, School of Mathematics and Natural Sciences, University of Southern Mississippi, Hattiesburg, MS, 39406, USA.; Center for Molecular and Cellular Biosciences, University of Southern Mississippi, Hattiesburg, MS, 39406, USA.
Banerjee S; Department of Chemistry and Biochemistry, University of Alabama, Tuscaloosa, AL, 35401, USA.
Ghosh A; Department of Chemistry and Biochemistry, University of Alabama, Tuscaloosa, AL, 35401, USA.
Rangachari V; Department of Chemistry and Biochemistry, School of Mathematics and Natural Sciences, University of Southern Mississippi, Hattiesburg, MS, 39406, USA. .; Center for Molecular and Cellular Biosciences, University of Southern Mississippi, Hattiesburg, MS, 39406, USA. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2023 Dec 05; Vol. 6 (1), pp. 1227. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:: Journal Article
MeSH Terms:: Prions*
Multiple System Atrophy*
Humans ; alpha-Synuclein/metabolism ; RNA/genetics ; Amyloid ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism

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Skocz do pozycji: 20.

Tytuł:: Synthesis and anti-prion aggregation activity of acylthiosemicarbazide analogues.
Autorzy:: Kim DH; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Kim J; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Lee H; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Lee D; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Im SM; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Kim YE; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Yoo M; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Cheon YP; Division of Developmental Biology and Physiology, Department of Biotechnology, Sungshin University, Seoul, Korea.
Bartz JC; Department of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, NE, USA.
Son YJ; Department of Pharmacy, Sunchon National University, Suncheon, Republic of Korea.
Choi EK; Ilsong Institute of Life Science, Hallym University, Seoul, Republic of Korea.; Department of Biomedical Gerontology, Graduate School of Hallym University, Chuncheon, Korea.
Kim YS; Ilsong Institute of Life Science, Hallym University, Seoul, Republic of Korea.
Jeon JH; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Kim HS; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Lee S; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Ryou C; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.
Nam TG; Department of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University ERICA campus, Ansan, Republic of Korea.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2191164.
Typ publikacji:: Journal Article
MeSH Terms:: Prions*/metabolism
Prion Diseases*/drug therapy
Prion Diseases*/metabolism
Prion Diseases*/pathology
Humans ; Prion Proteins/metabolism ; Brain ; Cells, Cultured

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