Temat: "Proline" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: HOCI Probe CPP Induces the Differentiation of Human Dermal Fibroblasts into Vascular Endothelial Cells through PHD2/HIF-1α/HEY1 Signaling Pathway.
Autorzy:: Cui X; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Qingdao 266237, China.
Wen J; School of Stomatology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China.
Li N; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Qingdao 266237, China.
Hao X; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Qingdao 266237, China.
Zhang S; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Qingdao 266237, China.
Zhao B; Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China.
Wu X; Engineering Laboratory for Biomaterials and Tissue Regeneration, Ningbo Stomatology Hospital, Ningbo 315040, China.; Savaid Stomatology School, Hangzhou Medical College, Hangzhou 310058, China.
Miao J; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Qingdao 266237, China.; The Key Laboratory of Cardiovascular Remodeling and Function Research, Shandong University Qilu Hospital, Chinese Ministry of Education and Chinese Ministry of Health, Jinan 250012, China.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Oct 04; Vol. 11 (19). Date of Electronic Publication: 2022 Oct 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Endothelial Cells*/metabolism
Hypoxia-Inducible Factor-Proline Dioxygenases*
Humans ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cell Cycle Proteins/metabolism ; Fibroblasts/metabolism ; Hypochlorous Acid/pharmacology ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Procollagen-Proline Dioxygenase/genetics ; Procollagen-Proline Dioxygenase/metabolism ; Prolyl Hydroxylases/metabolism ; RNA, Small Interfering/genetics ; Signal Transduction

Czasopismo naukowe

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Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2.
Autorzy:: Feng T; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.; Department of Medicine, The University of Hong Kong, Hong Kong, China.
Zhao X; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Gu P; Department of Endocrinology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Yang W; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.; Department of Medicine, The University of Hong Kong, Hong Kong, China.; The First Affiliated Hospital of Jinan University, Guangzhou, China.
Wang C; The First Affiliated Hospital of Jinan University, Guangzhou, China.
Guo Q; Department of Endocrinology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Long Q; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Liu Q; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.; Department of Medicine, The University of Hong Kong, Hong Kong, China.; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Cheng Y; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.; Department of Medicine, The University of Hong Kong, Hong Kong, China.
Li J; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.; Department of Medicine, The University of Hong Kong, Hong Kong, China.
Cheung CKY; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.; Department of Medicine, The University of Hong Kong, Hong Kong, China.
Wu D; Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, China.
Kong X; Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, China.
Xu Y; Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, China.
Ye D; Guangdong Pharmaceutical University, Guangzhou, China.
Hua S; Guangdong Pharmaceutical University, Guangzhou, China.
Loomes K; School of Biological Sciences and Maurice Wilkins Centre, University of Auckland, Auckland, New Zealand.
Xu A; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China. .; Department of Medicine, The University of Hong Kong, Hong Kong, China. .; Department of Pharmacy and Pharmacology, The University of Hong Kong, Hong Kong, China. .
Hui X; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China. .; Department of Medicine, The University of Hong Kong, Hong Kong, China. .; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China. .; Pokaż więcej
Źródło:: Nature communications [Nat Commun] 2022 Sep 05; Vol. 13 (1), pp. 5208. Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:: Journal Article
MeSH Terms:: Adipocytes*/immunology
Hypoxia-Inducible Factor-Proline Dioxygenases*/genetics
Hypoxia-Inducible Factor-Proline Dioxygenases*/immunology
Inflammation*/genetics
Inflammation*/immunology
Inflammation*/pathology
Lactate Dehydrogenase 5*/genetics
Lactate Dehydrogenase 5*/immunology
Lactic Acid*/immunology
Macrophages*/immunology
Adipose Tissue/immunology ; Animals ; Humans ; Insulin Resistance/genetics ; Insulin Resistance/immunology ; Insulin Resistance/physiology ; L-Lactate Dehydrogenase/genetics ; L-Lactate Dehydrogenase/immunology ; Mice ; Obesity/genetics ; Obesity/immunology ; Obesity/pathology ; Procollagen-Proline Dioxygenase/genetics ; Procollagen-Proline Dioxygenase/immunology ; Prolyl Hydroxylases

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Skocz do pozycji: 3.

Tytuł:: Microbial Proline Racemase-Proline Dehydrogenase Cascade for Efficient Production of D-proline and N-boc-5-hydroxy-L-proline from L-proline.
Autorzy:: Zhang F; Chongqing Key Laboratory of Big Data On Bio-Intelligence, School of Bioinformatics, Chongqing University of Posts and Telecommunications, Chongqing, 400065, People's Republic of China.
Xia S; Chongqing Key Laboratory of Big Data On Bio-Intelligence, School of Bioinformatics, Chongqing University of Posts and Telecommunications, Chongqing, 400065, People's Republic of China. .
Lin H; College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002, Henan, People's Republic of China.
Liu J; Chongqing Key Laboratory of Big Data On Bio-Intelligence, School of Bioinformatics, Chongqing University of Posts and Telecommunications, Chongqing, 400065, People's Republic of China.
Huang W; Chongqing Key Laboratory of Big Data On Bio-Intelligence, School of Bioinformatics, Chongqing University of Posts and Telecommunications, Chongqing, 400065, People's Republic of China.; Pokaż więcej
Źródło:: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2022 Sep; Vol. 194 (9), pp. 4135-4146. Date of Electronic Publication: 2022 May 30.
Typ publikacji:: Journal Article
MeSH Terms:: Amino Acid Isomerases*
Proline*
Escherichia coli/genetics ; Proline Oxidase ; Racemases and Epimerases

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Skocz do pozycji: 4.

Tytuł:: Screening prolyl hydroxylase domain 2 inhibitory activity of traditional Chinese medicine by CZE-UV.
Autorzy:: Zhang Y; CAS Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.; University of Chinese Academy of Sciences, Beijing, P. R. China.
Zhao M; Department of Cognitive Science, Institute of Cognition and Brain Sciences, Beijing, P. R. China.
Wang CB; CAS Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.
Wang Y; Department of Chinese Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P. R. China.
Nsanzamahoro S; CAS Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.; University of Chinese Academy of Sciences, Beijing, P. R. China.
Zhu LL; Department of Cognitive Science, Institute of Cognition and Brain Sciences, Beijing, P. R. China.
Wang WF; CAS Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.
Yang JL; CAS Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China.; Pokaż więcej
Źródło:: Electrophoresis [Electrophoresis] 2022 Aug; Vol. 43 (15), pp. 1601-1610. Date of Electronic Publication: 2022 Apr 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hypoxia-Inducible Factor-Proline Dioxygenases*/chemistry
Hypoxia-Inducible Factor-Proline Dioxygenases*/genetics
Hypoxia-Inducible Factor-Proline Dioxygenases*/metabolism
Medicine, Chinese Traditional*
Electrophoresis, Capillary ; Humans ; Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit ; Procollagen-Proline Dioxygenase/genetics ; Procollagen-Proline Dioxygenase/metabolism

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Skocz do pozycji: 5.

Tytuł:: Myeloid PHD2 deficiency accelerates neointima formation via Hif-1α.
Autorzy:: Christoph M; Internal Medicine and Cardiology, Heart Center Dresden, University Hospital at the Technische Universität, Dresden, Germany; Technische Universität, Dresden Campus, Chemnitz, Germany.
Pfluecke C; Internal Medicine and Cardiology, Heart Center Dresden, University Hospital at the Technische Universität, Dresden, Germany.
Mensch M; Internal Medicine and Cardiology, Heart Center Dresden, University Hospital at the Technische Universität, Dresden, Germany.
Augstein A; Internal Medicine and Cardiology, Heart Center Dresden, University Hospital at the Technische Universität, Dresden, Germany.
Jellinghaus S; Internal Medicine and Cardiology, Heart Center Dresden, University Hospital at the Technische Universität, Dresden, Germany.
Ende G; Internal Medicine and Cardiology, Heart Center Dresden, University Hospital at the Technische Universität, Dresden, Germany.
Mierke J; Internal Medicine and Cardiology, Heart Center Dresden, University Hospital at the Technische Universität, Dresden, Germany.
Franke K; Institute of Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, Dresden, Germany.
Wielockx B; Institute of Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, Dresden, Germany.
Ibrahim K; Internal Medicine and Cardiology, Heart Center Dresden, University Hospital at the Technische Universität, Dresden, Germany; Technische Universität, Dresden Campus, Chemnitz, Germany.
Poitz DM; Internal Medicine and Cardiology, Heart Center Dresden, University Hospital at the Technische Universität, Dresden, Germany; Institute of Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, Dresden, Germany. Electronic address: .; Pokaż więcej
Źródło:: Molecular immunology [Mol Immunol] 2022 Sep; Vol. 149, pp. 48-58. Date of Electronic Publication: 2022 Jun 17.
Typ publikacji:: Journal Article
MeSH Terms:: Basic Helix-Loop-Helix Transcription Factors*/genetics
Basic Helix-Loop-Helix Transcription Factors*/metabolism
Femoral Artery*/injuries
Femoral Artery*/metabolism
Hypoxia-Inducible Factor-Proline Dioxygenases*/deficiency
Hypoxia-Inducible Factor-Proline Dioxygenases*/genetics
Hypoxia-Inducible Factor-Proline Dioxygenases*/metabolism
Macrophages*/metabolism
Neointima*/genetics
Neointima*/metabolism
Plaque, Atherosclerotic*/genetics
Plaque, Atherosclerotic*/metabolism
Animals ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit ; Mice ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism ; Procollagen-Proline Dioxygenase/genetics

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Skocz do pozycji: 6.

Tytuł:: Tetrahydropyridin-4-ylpicolinoylglycines as novel and orally active prolyl hydroxylase 2 (PHD2) inhibitors for the treatment of renal anemia.
Autorzy:: Su K; Jiangsu Key Laboratory of Drug Design and Optimization, and Department of Chemistry, China Pharmaceutical University, Nanjing, 211198, China.
Li Z; Jiangsu Key Laboratory of Drug Design and Optimization, and Department of Chemistry, China Pharmaceutical University, Nanjing, 211198, China.
Zhang L; Jiangsu Key Laboratory of Drug Design and Optimization, and Department of Chemistry, China Pharmaceutical University, Nanjing, 211198, China.
Fang S; Jiangsu Key Laboratory of Drug Design and Optimization, and Department of Chemistry, China Pharmaceutical University, Nanjing, 211198, China.
Mao M; Jiangsu Key Laboratory of Drug Design and Optimization, and Department of Chemistry, China Pharmaceutical University, Nanjing, 211198, China.
Sun Z; Jiangsu Key Laboratory of Drug Design and Optimization, and Department of Chemistry, China Pharmaceutical University, Nanjing, 211198, China.
Zhang X; Jiangsu Key Laboratory of Drug Design and Optimization, and Department of Chemistry, China Pharmaceutical University, Nanjing, 211198, China. Electronic address: .; Pokaż więcej
Źródło:: European journal of medicinal chemistry [Eur J Med Chem] 2022 Aug 05; Vol. 238, pp. 114479. Date of Electronic Publication: 2022 May 25.
Typ publikacji:: Journal Article
MeSH Terms:: Anemia*/drug therapy
Anemia*/metabolism
Hypoxia-Inducible Factor-Proline Dioxygenases*/antagonists & inhibitors
Hypoxia-Inducible Factor-Proline Dioxygenases*/metabolism
Kidney Diseases*/drug therapy
Kidney Diseases*/metabolism
Prolyl-Hydroxylase Inhibitors*/pharmacology
Pyridines*/pharmacology
Animals ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mice ; Mice, Inbred C57BL ; Procollagen-Proline Dioxygenase/metabolism

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Skocz do pozycji: 7.

Tytuł:: Proline Oxidation Supports Mitochondrial ATP Production When Complex I Is Inhibited.
Autorzy:: Pallag G; Department of Biochemistry and Molecular Biology, Semmelweis University, 1094 Budapest, Hungary.
Nazarian S; Department of Biochemistry and Molecular Biology, Semmelweis University, 1094 Budapest, Hungary.
Ravasz D; Department of Biochemistry and Molecular Biology, Semmelweis University, 1094 Budapest, Hungary.
Bui D; Department of Biochemistry and Molecular Biology, Semmelweis University, 1094 Budapest, Hungary.
Komlódi T; Oroboros Instruments, 6020 Innsbruck, Austria.
Doerrier C; Oroboros Instruments, 6020 Innsbruck, Austria.
Gnaiger E; Oroboros Instruments, 6020 Innsbruck, Austria.
Seyfried TN; Biology Department, Boston College, Chestnut Hill, MA 02467, USA.
Chinopoulos C; Department of Biochemistry and Molecular Biology, Semmelweis University, 1094 Budapest, Hungary.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 May 04; Vol. 23 (9). Date of Electronic Publication: 2022 May 04.
Typ publikacji:: Journal Article
MeSH Terms:: Proline Oxidase*/metabolism
Ubiquinone*/metabolism
Adenosine Triphosphatases/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Electron Transport Complex I/metabolism ; Glutamic Acid/metabolism ; Mice ; Mitochondria/metabolism ; Proline/metabolism

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Skocz do pozycji: 8.

Tytuł:: Production of functional recombinant prolyl hydroxylase-2 enzyme in insect cells for small molecule inhibitor screening studies.
Autorzy:: Guo Z; School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China.
Zi J; School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China.
Hao Y; School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China.
Li Y; School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China.
Liu Z; School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China.
Zhao Q; School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China.
Hao L; School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China.
Diao A; School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, China. Electronic address: .; Pokaż więcej
Źródło:: Protein expression and purification [Protein Expr Purif] 2022 Jun; Vol. 194, pp. 106073. Date of Electronic Publication: 2022 Feb 19.
Typ publikacji:: Journal Article
MeSH Terms:: Dioxygenases*
Hypoxia-Inducible Factor-Proline Dioxygenases*/genetics
Animals ; Humans ; Insecta/metabolism ; Procollagen-Proline Dioxygenase/metabolism ; Prolyl Hydroxylases/genetics ; Recombinant Proteins/genetics ; Recombinant Proteins/pharmacology

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Skocz do pozycji: 9.

Tytuł:: NSAIDs Induce Proline Dehydrogenase/Proline Oxidase-Dependent and Independent Apoptosis in MCF7 Breast Cancer Cells.
Autorzy:: Kazberuk A; Department of Medicinal Chemistry, Medical University of Bialystok, Mickiewicza 2D, 15-222 Bialystok, Poland.
Chalecka M; Department of Medicinal Chemistry, Medical University of Bialystok, Mickiewicza 2D, 15-222 Bialystok, Poland.
Palka J; Department of Medicinal Chemistry, Medical University of Bialystok, Mickiewicza 2D, 15-222 Bialystok, Poland.
Bielawska K; Department of Analysis and Bioanalysis of Medicines, Medical University of Bialystok, Mickiewicza 2D, 15-222 Bialystok, Poland.
Surazynski A; Department of Medicinal Chemistry, Medical University of Bialystok, Mickiewicza 2D, 15-222 Bialystok, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 30; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 30.
Typ publikacji:: Journal Article
MeSH Terms:: Breast Neoplasms*/drug therapy
Proline Oxidase*/genetics
Proline Oxidase*/metabolism
Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Apoptosis ; Cyclooxygenase 2/pharmacology ; Female ; Humans ; MCF-7 Cells ; Oxidoreductases ; Proline/metabolism ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 10.

Tytuł:: Structures of L-proline trans-hydroxylase reveal the catalytic specificity and provide deeper insight into AKG-dependent hydroxylation.
Autorzy:: Hu X; Department of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.
Huang X; Department of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.
Liu J; Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Tianjin, People's Republic of China.
Zheng P; Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Tianjin, People's Republic of China.
Gong W; Department of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.
Yang L; Department of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.; Pokaż więcej
Źródło:: Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2023 Apr 01; Vol. 79 (Pt 4), pp. 318-325. Date of Electronic Publication: 2023 Mar 28.
Typ publikacji:: Journal Article
MeSH Terms:: Proline*/chemistry
Prolyl Hydroxylases*/chemistry
Prolyl Hydroxylases*/metabolism
Mixed Function Oxygenases/metabolism ; Ketoglutaric Acids ; Hydroxylation

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Skocz do pozycji: 11.

Tytuł:: Crystal structure analysis of N-acetylated proline and ring size analogs.
Autorzy:: Schnitzer T; Laboratory of Organic Chemistry, ETH Zürich, D-CHAB, Zurich, Switzerland.
Trapp N; Laboratory of Organic Chemistry, ETH Zürich, D-CHAB, Zurich, Switzerland.
Fischer LM; Laboratory of Organic Chemistry, ETH Zürich, D-CHAB, Zurich, Switzerland.
Wennemers H; Laboratory of Organic Chemistry, ETH Zürich, D-CHAB, Zurich, Switzerland.; Pokaż więcej
Źródło:: Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2023 Jun; Vol. 29 (6), pp. e3473. Date of Electronic Publication: 2023 Jan 31.
Typ publikacji:: Journal Article
MeSH Terms:: Proline*/chemistry
Azetidinecarboxylic Acid*/chemistry
Molecular Conformation ; Carboxylic Acids

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Skocz do pozycji: 12.

Tytuł:: Tissue-specific collagen hydroxylation at GEP/GDP triplets mediated by P4HA2.
Autorzy:: Wilhelm D; Université de Lorraine, CNRS, IMoPA, UMR 7365, Nancy F-54000, France.
Wurtz A; Université de Lorraine, CNRS, IMoPA, UMR 7365, Nancy F-54000, France.
Abouelfarah H; Université de Lorraine, CNRS, IMoPA, UMR 7365, Nancy F-54000, France.
Sanchez G; Université de Lorraine, CNRS, IMoPA, UMR 7365, Nancy F-54000, France.
Bui C; Université de Lorraine, CNRS, IMoPA, UMR 7365, Nancy F-54000, France.
Vincourt JB; Université de Lorraine, CNRS, IMoPA, UMR 7365, Nancy F-54000, France; Proteomics core facility of the University of Lorraine, CNRS, INSERM, IBSLor, UMS2008/US40, Nancy F-54000, France. Electronic address: .; Pokaż więcej
Źródło:: Matrix biology : journal of the International Society for Matrix Biology [Matrix Biol] 2023 May; Vol. 119, pp. 141-153. Date of Electronic Publication: 2023 Mar 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Collagen*/metabolism
Procollagen-Proline Dioxygenase*/chemistry
Procollagen-Proline Dioxygenase*/genetics
Procollagen-Proline Dioxygenase*/metabolism
Mice ; Animals ; Hydroxylation ; Prolyl Hydroxylases/chemistry ; Extracellular Matrix/metabolism

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Skocz do pozycji: 13.

Tytuł:: Small proline-rich proteins (SPRRs) are epidermally produced antimicrobial proteins that defend the cutaneous barrier by direct bacterial membrane disruption.
Autorzy:: Zhang C; Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, United States.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Hu Z; Department of Immunology, University of Texas Southwestern Medical Center, Dallas, United States.; State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Lone AG; Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, United States.
Artami M; Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, United States.
Edwards M; Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, United States.
Zouboulis CC; Department of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodore Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany.
Stein M; Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, United States.
Harris-Tryon TA; Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, United States.; Department of Immunology, University of Texas Southwestern Medical Center, Dallas, United States.; Pokaż więcej
Źródło:: ELife [Elife] 2022 Mar 02; Vol. 11. Date of Electronic Publication: 2022 Mar 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cornified Envelope Proline-Rich Proteins*
Methicillin-Resistant Staphylococcus aureus*
Animals ; Anti-Bacterial Agents ; Lipopolysaccharides ; Membrane Proteins/metabolism ; Mice ; Proline

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Skocz do pozycji: 14.

Tytuł:: Synergistic n → π* and n N → π* Ar interactions in C-terminal modified prolines: effect on Xaa-Pro cis / trans equilibrium.
Autorzy:: Deka JKR; New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore 560064, India. .
Borah D; New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore 560064, India. .
Das P; New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore 560064, India. .
Sahariah B; New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore 560064, India. .
Vishnoi P; New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore 560064, India. .
Sarma BK; New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore 560064, India. .; Pokaż więcej
Źródło:: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2023 May 16; Vol. 59 (40), pp. 6080-6083. Date of Electronic Publication: 2023 May 16.
Typ publikacji:: Journal Article
MeSH Terms:: Proline*/chemistry
Amides*/chemistry
Protein Structure, Secondary ; Collagen/chemistry ; Protein Conformation

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Skocz do pozycji: 15.

Tytuł:: Assessment of proline function in higher plants under extreme temperatures.
Autorzy:: Raza A; College of Agriculture, Fujian Agriculture and Forestry University (FAFU), Fuzhou, China.
Charagh S; State Key Laboratory of Rice Biology, China National Rice Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Hangzhou, China.
Abbas S; Department of Botany, Faculty of Life Sciences, Government College University, Faisalabad, Pakistan.
Hassan MU; Research Center on Ecological Sciences, Jiangxi Agricultural University, Nanchang, China.
Saeed F; Department of Agricultural Genetic Engineering, Faculty of Agricultural Sciences and Technologies, Nigde Omer Halisdemir University, Nigde, Turkey.
Haider S; Plant Biochemistry and Molecular Biology Lab, Department of Plant Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Sharif R; Department of Horticulture, School of Horticulture and Landscape, Yangzhou University, Yangzhou, China.
Anand A; Division of Plant Physiology, ICAR-Indian Agricultural Research Institute, Pusa, New Delhi, India.
Corpas FJ; Group of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Stress, Development and Signaling in Plants, Estación Experimental del Zaidín, Spanish National Research Council, CSIC, Granada, Spain.
Jin W; Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China), Institute of Forestry and Pomology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Varshney RK; State Agricultural Biotechnology Centre, Centre for Crop and Food Innovation, Murdoch University, Murdoch, WA, Australia.; Pokaż więcej
Źródło:: Plant biology (Stuttgart, Germany) [Plant Biol (Stuttg)] 2023 Apr; Vol. 25 (3), pp. 379-395. Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Hot Temperature*
Proline*/metabolism
Temperature ; Plants/metabolism ; Stress, Physiological/physiology ; Sugars/metabolism

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 16.

Tytuł:: Proline-related metabolites: Towards biological diagnosis of depression.
Autorzy:: Mayneris-Perxachs J; Department of Diabetes, Endocrinology and Nutrition, Dr. Josep Trueta University Hospital, Girona, Spain.; Nutrition, Eumetabolism and Health Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain.
Fernández-Real JM; Department of Diabetes, Endocrinology and Nutrition, Dr. Josep Trueta University Hospital, Girona, Spain.; Nutrition, Eumetabolism and Health Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.; CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain.; Department of Medical Sciences, School of Medicine, University of Girona, Girona, Spain.; Pokaż więcej
Źródło:: Psychiatry and clinical neurosciences [Psychiatry Clin Neurosci] 2023 Apr; Vol. 77 (4), pp. 195.
Typ publikacji:: Editorial
MeSH Terms:: Proline*
Depression*/diagnosis
Humans

Opinia redakcyjna

na półce

Szczegóły

Skocz do pozycji: 17.

Tytuł:: Beyond keratinocyte differentiation: emerging new biology of small proline-rich proteins.
Autorzy:: Zabini A; Department of Radiation Oncology, Inselspital, Bern University Hospital, Freiburgstrasse 8, 3008 Bern, Switzerland; Department for BioMedical Research, Radiation Oncology, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Zimmer Y; Department of Radiation Oncology, Inselspital, Bern University Hospital, Freiburgstrasse 8, 3008 Bern, Switzerland; Department for BioMedical Research, Radiation Oncology, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Medová M; Department of Radiation Oncology, Inselspital, Bern University Hospital, Freiburgstrasse 8, 3008 Bern, Switzerland; Department for BioMedical Research, Radiation Oncology, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland. Electronic address: .; Pokaż więcej
Źródło:: Trends in cell biology [Trends Cell Biol] 2023 Jan; Vol. 33 (1), pp. 5-8. Date of Electronic Publication: 2022 Sep 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Proline*/metabolism
Cornified Envelope Proline-Rich Proteins*/metabolism
Humans ; Proteins/metabolism ; Keratinocytes ; Biology

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 18.

Tytuł:: Probing Peptidylprolyl Bond cis/trans Status Using Distal F NMR Reporters.
Autorzy:: Killoran PM; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, Merseyside, L3 3AF, UK.
Hanson GSM; EaStChem School of Chemistry, The University of Edinburgh Joseph Black Building, David Brewster Road, Edinburgh, EH14 4AS, UK.
Verhoork SJM; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, Merseyside, L3 3AF, UK.
Smith M; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, Merseyside, L3 3AF, UK.
Del Gobbo D; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, Merseyside, L3 3AF, UK.
Lian LY; Institute of Systems, Molecular and Integrative Biology, The University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK.
Coxon CR; EaStChem School of Chemistry, The University of Edinburgh Joseph Black Building, David Brewster Road, Edinburgh, EH14 4AS, UK.; Pokaż więcej
Źródło:: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 Mar 16; Vol. 29 (16), pp. e202203017. Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Peptides*/chemistry
Proline*/chemistry
Protein Conformation ; Magnetic Resonance Spectroscopy ; Isomerism

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 19.

Tytuł:: The N-terminal Proline Hinge Motif Controls the Structure of Bovine Herpesvirus 1-encoded Inhibitor of the Transporter Associated with Antigen Processing Required for its Immunomodulatory Function.
Autorzy:: Graul M; Laboratory of Virus Molecular Biology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, 80-307 Gdańsk, Poland.
Karska N; Laboratory of Virus Molecular Biology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, 80-307 Gdańsk, Poland; Department of Biomedical Chemistry, Faculty of Chemistry, University of Gdańsk, 80-308 Gdańsk, Poland.
Wąchalska M; Laboratory of Virus Molecular Biology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, 80-307 Gdańsk, Poland.
Krupa P; Institute of Physics, Polish Academy of Sciences, 02-668 Warsaw, Poland.
Ślusarz MJ; Department of Theoretical Chemistry, Faculty of Chemistry, University of Gdańsk, 80-308 Gdańsk, Poland.
Lubocki M; Laboratory of Virus Molecular Biology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, 80-307 Gdańsk, Poland.
Bieńkowska-Szewczyk K; Laboratory of Virus Molecular Biology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, 80-307 Gdańsk, Poland.
Rodziewicz-Motowidło S; Department of Biomedical Chemistry, Faculty of Chemistry, University of Gdańsk, 80-308 Gdańsk, Poland.
Sieradzan AK; Department of Theoretical Chemistry, Faculty of Chemistry, University of Gdańsk, 80-308 Gdańsk, Poland. Electronic address: .
Lipińska AD; Laboratory of Virus Molecular Biology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, 80-307 Gdańsk, Poland. Electronic address: .; Pokaż więcej
Źródło:: Journal of molecular biology [J Mol Biol] 2023 Mar 01; Vol. 435 (5), pp. 167964. Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antigen Presentation*
Herpesvirus 1, Bovine*/immunology
Proline*/chemistry
Proline*/genetics
Membrane Transport Proteins/metabolism ; Amino Acid Motifs ; Protein Transport

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 20.

Tytuł:: HIF-PHD inhibitor regulates the function of group2 innate lymphoid cells and polarization of M2 macrophages.
Autorzy:: Nagashima R; Department of Microbiology and Immunology, Showa University School of Medicine, Tokyo, Japan. .
Ishikawa H; Department of Microbiology and Immunology, Showa University School of Medicine, Tokyo, Japan.
Kuno Y; Department of Microbiology and Immunology, Showa University School of Medicine, Tokyo, Japan.; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Kohda C; Department of Microbiology and Immunology, Showa University School of Medicine, Tokyo, Japan.
Iyoda M; Department of Microbiology and Immunology, Showa University School of Medicine, Tokyo, Japan.; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Feb 01; Vol. 13 (1), pp. 1867. Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Erythropoietin*/metabolism
Hypoxia-Inducible Factor-Proline Dioxygenases*/antagonists & inhibitors
Hypoxia-Inducible Factor-Proline Dioxygenases*/metabolism
Kidney Diseases*/metabolism
Prolyl-Hydroxylase Inhibitors*/pharmacology
Humans ; Fibrosis ; Immunity, Innate ; Kidney/metabolism ; Lymphocytes/metabolism ; Prolyl Hydroxylases/metabolism ; Macrophage Activation

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