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Wyszukujesz frazę ""Promoter Regions, Genetic"" wg kryterium: Temat


Tytuł:
Therapeutic targeting of PLK1 in TERT promoter-mutant hepatocellular carcinoma.
Autorzy:
Tang Q; Department of Radiation Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Hu G; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Sang Y; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Chen Y; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Wei G; Department of Radiation Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhu M; Department of Radiation Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Chen M; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Li S; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Liu R; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Peng Z; Department of Radiation Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Cancer Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 May; Vol. 14 (5), pp. e1703.
Typ publikacji:
Journal Article
MeSH Terms:
Telomerase*/genetics
Telomerase*/antagonists & inhibitors
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Liver Neoplasms*/pathology
Polo-Like Kinase 1*
Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/antagonists & inhibitors
Proto-Oncogene Proteins*/genetics
Proto-Oncogene Proteins*/antagonists & inhibitors
Cell Cycle Proteins*/genetics
Cell Cycle Proteins*/antagonists & inhibitors
Promoter Regions, Genetic*/genetics
Promoter Regions, Genetic*/drug effects
Humans ; Animals ; Mutation ; Mice ; Cell Line, Tumor ; Apoptosis/drug effects ; Apoptosis/genetics
Czasopismo naukowe
Tytuł:
Insertion sequence IS6770 modulates potassium symporter kup transcription in Enterococcus faecalis JH2-2 under low pH conditions.
Autorzy:
Acciarri G; Laboratorio de Fisiología y Genética de Bacterias Lácticas, Instituto de Biología Molecular y Celular de Rosario (IBR), sede Facultad de Ciencias Bioquímicas y Farmacéuticas (FBioyF), Universidad Nacional de Rosario (UNR), Consejo Nacional de Ciencia y Tecnología (CONICET), Suipacha 590, Rosario, Argentina; Laboratorio de Biotecnología e Inocuidad de los Alimentos, Área de Biotecnología de los Alimentos (FBioyF, UNR- Municipalidad de Granadero Baigorria), Sede Suipacha 590, Rosario, Argentina.
Taborra ME; Laboratorio de Fisiología y Genética de Bacterias Lácticas, Instituto de Biología Molecular y Celular de Rosario (IBR), sede Facultad de Ciencias Bioquímicas y Farmacéuticas (FBioyF), Universidad Nacional de Rosario (UNR), Consejo Nacional de Ciencia y Tecnología (CONICET), Suipacha 590, Rosario, Argentina; Laboratorio de Biotecnología e Inocuidad de los Alimentos, Área de Biotecnología de los Alimentos (FBioyF, UNR- Municipalidad de Granadero Baigorria), Sede Suipacha 590, Rosario, Argentina.
Gizzi FO; Laboratorio de Fisiología y Genética de Bacterias Lácticas, Instituto de Biología Molecular y Celular de Rosario (IBR), sede Facultad de Ciencias Bioquímicas y Farmacéuticas (FBioyF), Universidad Nacional de Rosario (UNR), Consejo Nacional de Ciencia y Tecnología (CONICET), Suipacha 590, Rosario, Argentina; Laboratorio de Biotecnología e Inocuidad de los Alimentos, Área de Biotecnología de los Alimentos (FBioyF, UNR- Municipalidad de Granadero Baigorria), Sede Suipacha 590, Rosario, Argentina.
Blancato VS; Laboratorio de Fisiología y Genética de Bacterias Lácticas, Instituto de Biología Molecular y Celular de Rosario (IBR), sede Facultad de Ciencias Bioquímicas y Farmacéuticas (FBioyF), Universidad Nacional de Rosario (UNR), Consejo Nacional de Ciencia y Tecnología (CONICET), Suipacha 590, Rosario, Argentina; Laboratorio de Biotecnología e Inocuidad de los Alimentos, Área de Biotecnología de los Alimentos (FBioyF, UNR- Municipalidad de Granadero Baigorria), Sede Suipacha 590, Rosario, Argentina.
Magni C; Laboratorio de Fisiología y Genética de Bacterias Lácticas, Instituto de Biología Molecular y Celular de Rosario (IBR), sede Facultad de Ciencias Bioquímicas y Farmacéuticas (FBioyF), Universidad Nacional de Rosario (UNR), Consejo Nacional de Ciencia y Tecnología (CONICET), Suipacha 590, Rosario, Argentina; Laboratorio de Biotecnología e Inocuidad de los Alimentos, Área de Biotecnología de los Alimentos (FBioyF, UNR- Municipalidad de Granadero Baigorria), Sede Suipacha 590, Rosario, Argentina. Electronic address: .
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Źródło:
International journal of food microbiology [Int J Food Microbiol] 2024 Jul 16; Vol. 419, pp. 110736. Date of Electronic Publication: 2024 May 09.
Typ publikacji:
Journal Article
MeSH Terms:
Enterococcus faecalis*/genetics
Enterococcus faecalis*/metabolism
Promoter Regions, Genetic*
Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
Gene Expression Regulation, Bacterial*
Hydrogen-Ion Concentration ; DNA Transposable Elements ; Transcription, Genetic ; Potassium/metabolism
Czasopismo naukowe
Tytuł:
VlMYB4 and VlCDF3 co-targeted the VlLOG11 promoter to regulate fruit setting in grape (Vitis vinifera L).
Autorzy:
Wang LL; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China.
Shi Q; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China.
Jing P; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China.
Wang R; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China.
Zhang H; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China.
Liu Y; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China.
Li C; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China.
Shi T; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China.
Zhang L; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China.
Yu YH; College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang, Henan Province, 471023, China. .
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Źródło:
Plant cell reports [Plant Cell Rep] 2024 Jul 15; Vol. 43 (8), pp. 194. Date of Electronic Publication: 2024 Jul 15.
Typ publikacji:
Journal Article
MeSH Terms:
Vitis*/genetics
Vitis*/metabolism
Gene Expression Regulation, Plant*
Fruit*/genetics
Fruit*/metabolism
Fruit*/growth & development
Plant Proteins*/genetics
Plant Proteins*/metabolism
Promoter Regions, Genetic*/genetics
Cytokinins*/metabolism
Plants, Genetically Modified ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Solanum lycopersicum/genetics ; Solanum lycopersicum/metabolism ; Solanum lycopersicum/growth & development ; Phenylurea Compounds/pharmacology ; Signal Transduction/genetics ; Pyridines
Czasopismo naukowe
Tytuł:
Exploring non-coding genetic variability in ACE2: Functional annotation and in vitro validation of regulatory variants.
Autorzy:
Giovannetti A; Clinical Genomics Laboratory, Fondazione IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, snc, 71013 S. Giovanni Rotondo (FG), Italy. Electronic address: .
Lazzari S; Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy. Electronic address: .
Mangoni M; Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy; Bioinformatics Laboratory, Fondazione IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, snc, 71013 S. Giovanni Rotondo (FG), Italy. Electronic address: .
Traversa A; Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy; Dipartimento di Scienze della Vita, della Salute e delle Professioni Sanitarie, Università degli Studi 'Link Campus University', Via del Casale di San Pio V 44, 00165 Roma, Italy. Electronic address: .
Mazza T; Bioinformatics Laboratory, Fondazione IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini, snc, 71013 S. Giovanni Rotondo (FG), Italy. Electronic address: .
Parisi C; Institute of Biochemistry and Cell Biology, CNR-National Research Council, Via Ercole Ramarini, 32, 00015 Monterotondo Scalo (RM), Italy. Electronic address: .
Caputo V; Department of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy. Electronic address: .
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Źródło:
Gene [Gene] 2024 Jul 15; Vol. 915, pp. 148422. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin-Converting Enzyme 2*/genetics
Angiotensin-Converting Enzyme 2*/metabolism
Promoter Regions, Genetic*
Polymorphism, Single Nucleotide*
COVID-19*/genetics
COVID-19*/virology
SARS-CoV-2*/genetics
Humans ; 3' Untranslated Regions/genetics ; Genetic Variation
Czasopismo naukowe
Tytuł:
DNA methylation analysis in plasma for early diagnosis in lung adenocarcinoma.
Autorzy:
Jin Y; Department of Thoracic Surgery, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu, China.
Lu R
Liu F
Jiang G
Wang R
Zheng M
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Źródło:
Medicine [Medicine (Baltimore)] 2024 Jul 12; Vol. 103 (28), pp. e38867.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Methylation*
Tumor Suppressor Proteins*/genetics
Tumor Suppressor Proteins*/blood
Adenocarcinoma of Lung*/genetics
Adenocarcinoma of Lung*/diagnosis
Adenocarcinoma of Lung*/blood
Lung Neoplasms*/diagnosis
Lung Neoplasms*/genetics
Lung Neoplasms*/blood
Early Detection of Cancer*/methods
Biomarkers, Tumor*/blood
Biomarkers, Tumor*/genetics
Promoter Regions, Genetic*
Homeodomain Proteins*/genetics
Homeodomain Proteins*/blood
Humans ; Male ; Female ; Middle Aged ; Aged ; Bronchoalveolar Lavage Fluid/chemistry ; ROC Curve ; Adult ; Sensitivity and Specificity ; Case-Control Studies
Czasopismo naukowe
Tytuł:
BRD7 facilitates ferroptosis via modulating clusterin promoter hypermethylation and suppressing AMPK signaling in diabetes-induced testicular damage.
Autorzy:
Xiao Y; Department of Urology, Affiliated Hospital of Guizhou Medical University, Clinical Medical College of Guizhou Medical University, No.28 Guiyi Street, Yunyan District, Guiyang, Guizhou Province, 550004, China.
Liang Z; Department of Urology, Affiliated Hospital of Guizhou Medical University, Clinical Medical College of Guizhou Medical University, No.28 Guiyi Street, Yunyan District, Guiyang, Guizhou Province, 550004, China.
Qiao J; Department of Urology, School of Nursing, Affiliated Hospital of Guizhou Medical University, Guizhou Medical University, Guiyang, Guizhou Province, 550004, China.
Zhu Z; Department of Urology, Affiliated Hospital of Guizhou Medical University, Clinical Medical College of Guizhou Medical University, No.28 Guiyi Street, Yunyan District, Guiyang, Guizhou Province, 550004, China.
Liu B; Department of Urology, Affiliated Hospital of Guizhou Medical University, Clinical Medical College of Guizhou Medical University, No.28 Guiyi Street, Yunyan District, Guiyang, Guizhou Province, 550004, China.
Tian Y; Department of Urology, Affiliated Hospital of Guizhou Medical University, Clinical Medical College of Guizhou Medical University, No.28 Guiyi Street, Yunyan District, Guiyang, Guizhou Province, 550004, China. .
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Źródło:
Molecular medicine (Cambridge, Mass.) [Mol Med] 2024 Jul 12; Vol. 30 (1), pp. 100. Date of Electronic Publication: 2024 Jul 12.
Typ publikacji:
Journal Article
MeSH Terms:
AMP-Activated Protein Kinases*/metabolism
Clusterin*/genetics
Clusterin*/metabolism
Diabetes Mellitus, Experimental*/metabolism
Diabetes Mellitus, Experimental*/genetics
Diabetes Mellitus, Experimental*/complications
DNA Methylation*
Ferroptosis*/genetics
Promoter Regions, Genetic*
Signal Transduction*
Testis*/metabolism
Testis*/pathology
Animals ; Male ; Mice ; Cell Line ; DNA Methyltransferase 3A/metabolism ; Enhancer of Zeste Homolog 2 Protein/genetics ; Enhancer of Zeste Homolog 2 Protein/metabolism ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
miPEP31 alleviates Ang II-induced hypertension in mice by occupying Cebpα binding sites in the pri-miR-31 promoter.
Autorzy:
Li X; The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension,, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, China.; Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Zhou H; Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Lu P; Precision Research Center for Refractory Diseases, Institute for Clinical Research, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Fang Z; The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension,, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, China.
Shi G; The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension,, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, China.
Tong X; The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension,, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, China.
Chen W; The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension,, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, China.
Jiang G; The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension,, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, China.
Zhang P; The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension,, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, China.
Tian J; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital,, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .; Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, Clinical Trials Center, Ruijin Hospital,, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
Li Q; The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension,, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, China. .
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Źródło:
Cardiovascular diabetology [Cardiovasc Diabetol] 2024 Jul 11; Vol. 23 (1), pp. 249. Date of Electronic Publication: 2024 Jul 11.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/metabolism
MicroRNAs*/genetics
Hypertension*/chemically induced
Hypertension*/metabolism
Hypertension*/physiopathology
Hypertension*/genetics
Angiotensin II*
Disease Models, Animal*
Mice, Inbred C57BL*
Promoter Regions, Genetic*
Blood Pressure*/drug effects
Mice, Knockout*
T-Lymphocytes, Regulatory*/drug effects
T-Lymphocytes, Regulatory*/metabolism
T-Lymphocytes, Regulatory*/immunology
Kidney*/metabolism
Kidney*/pathology
Animals ; Binding Sites ; Male ; Mice ; Gene Expression Regulation ; Signal Transduction ; CCAAT-Enhancer-Binding Proteins/metabolism ; CCAAT-Enhancer-Binding Proteins/genetics ; Antihypertensive Agents/pharmacology ; Humans
Czasopismo naukowe
Tytuł:
Preoperative prediction of MGMT promoter methylation in glioblastoma based on multiregional and multi-sequence MRI radiomics analysis.
Autorzy:
Li L; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xiao F; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Wang S; Department of Radiology, Sir Run Run Shaw Hospital (SRRSH) of School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Kuang S; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Li Z; Department of Neurosurgery&Brain Glioma Center, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhong Y; Department of Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xu D; Department of Nuclear Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Cai Y; Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Li S; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Chen J; Wuhan GE Healthcare, Wuhan, China.
Liu Y; Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Li J; Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Li H; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China. .
Xu H; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jul 11; Vol. 14 (1), pp. 16031. Date of Electronic Publication: 2024 Jul 11.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/genetics
Glioblastoma*/diagnostic imaging
Glioblastoma*/pathology
DNA Repair Enzymes*/genetics
DNA Modification Methylases*/genetics
Tumor Suppressor Proteins*/genetics
Promoter Regions, Genetic*
Magnetic Resonance Imaging*/methods
DNA Methylation*
Brain Neoplasms*/genetics
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/pathology
Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Adult ; Aged ; Prognosis ; ROC Curve ; Radiomics
Czasopismo naukowe
Tytuł:
Basis of gene-specific transcription regulation by the Integrator complex.
Autorzy:
Sabath K; Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland. Electronic address: .
Nabih A; Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland.
Arnold C; European Molecular Biology Laboratory, Structural and Computational Biology Unit, 69117 Heidelberg, Germany.
Moussa R; European Molecular Biology Laboratory, Structural and Computational Biology Unit, 69117 Heidelberg, Germany.
Domjan D; Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland.
Zaugg JB; European Molecular Biology Laboratory, Structural and Computational Biology Unit, 69117 Heidelberg, Germany.
Jonas S; Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland. Electronic address: .
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Źródło:
Molecular cell [Mol Cell] 2024 Jul 11; Vol. 84 (13), pp. 2525-2541.e12. Date of Electronic Publication: 2024 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
RNA Polymerase II*/metabolism
RNA Polymerase II*/genetics
Promoter Regions, Genetic*
Gene Expression Regulation*
Transcription Factors*/metabolism
Transcription Factors*/genetics
Transcription, Genetic*
Humans ; Binding Sites ; Protein Binding ; HEK293 Cells ; Cilia/metabolism ; Cilia/genetics
Czasopismo naukowe
Tytuł:
Rapid evolution of promoters from germline-specifically expressed genes including transposon silencing factors.
Autorzy:
McQuarrie DWJ; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.; Birmingham Centre for Genome Biology, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Alizada A; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, CB2 0RE, UK.
Nicholson BC; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, CB2 0RE, UK.
Soller M; School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. .; Birmingham Centre for Genome Biology, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. .
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Źródło:
BMC genomics [BMC Genomics] 2024 Jul 08; Vol. 25 (1), pp. 678. Date of Electronic Publication: 2024 Jul 08.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Transposable Elements*/genetics
Promoter Regions, Genetic*
Evolution, Molecular*
Germ Cells*/metabolism
Gene Silencing*
RNA, Small Interfering*/genetics
RNA, Small Interfering*/metabolism
Animals ; Drosophila Proteins/genetics ; Drosophila/genetics ; Argonaute Proteins/genetics
Czasopismo naukowe
Tytuł:
Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9.
Autorzy:
Eaton JD; The Living Systems Institute, University of Exeter, Exeter, United Kingdom.
Board J; The Living Systems Institute, University of Exeter, Exeter, United Kingdom.
Davidson L; The Living Systems Institute, University of Exeter, Exeter, United Kingdom.
Estell C; The Living Systems Institute, University of Exeter, Exeter, United Kingdom.
West S; The Living Systems Institute, University of Exeter, Exeter, United Kingdom.
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Źródło:
ELife [Elife] 2024 Jul 08; Vol. 13. Date of Electronic Publication: 2024 Jul 08.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclin-Dependent Kinase 9*/metabolism
Cyclin-Dependent Kinase 9*/genetics
Promoter Regions, Genetic*
Transcription Initiation, Genetic*
Humans ; RNA Polymerase II/metabolism ; RNA Polymerase II/genetics ; Transcription, Genetic ; Gene Expression Regulation ; Nuclear Proteins ; Transcriptional Elongation Factors
Czasopismo naukowe
Tytuł:
Reduction of ZFX levels decreases histone H4 acetylation and increases Pol2 pausing at target promoters.
Autorzy:
Hsu E; Department of Biochemistry and Molecular Medicine and the Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Hutchison K; Department of Biochemistry and Molecular Medicine and the Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Liu Y; Department of Biochemistry and Molecular Medicine and the Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Nicolet CM; Department of Biochemistry and Molecular Medicine and the Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Schreiner S; Department of Biochemistry and Molecular Medicine and the Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Zemke NR; Department of Cellular and Molecular Medicine, UCSD School of Medicine, La Jolla, CA 92093, USA.
Farnham PJ; Department of Biochemistry and Molecular Medicine and the Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jul 08; Vol. 52 (12), pp. 6850-6865.
Typ publikacji:
Journal Article
MeSH Terms:
Promoter Regions, Genetic*
Histones*/metabolism
Chromatin*/metabolism
Acetylation ; Humans ; RNA Polymerase II/metabolism ; Zinc Fingers ; Protein Binding ; Transcriptional Activation ; Mice ; Transcription Factors/metabolism ; Transcription Factors/genetics ; CpG Islands ; Animals
Czasopismo naukowe
Tytuł:
New Drosophila promoter-associated architectural protein Mzfp1 interacts with CP190 and is required for housekeeping gene expression and insulator activity.
Autorzy:
Sokolov V; Department of the Control of Genetic Processes, Institute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia.
Kyrchanova O; Department of the Control of Genetic Processes, Institute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia.
Klimenko N; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia.
Fedotova A; Department of the Control of Genetic Processes, Institute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia.
Ibragimov A; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia.
Maksimenko O; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia.
Georgiev P; Department of the Control of Genetic Processes, Institute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Jul 08; Vol. 52 (12), pp. 6886-6905.
Typ publikacji:
Journal Article
MeSH Terms:
Drosophila Proteins*/metabolism
Drosophila Proteins*/genetics
Promoter Regions, Genetic*
Insulator Elements*/genetics
Drosophila melanogaster*/genetics
Drosophila melanogaster*/metabolism
Nuclear Proteins*/metabolism
Nuclear Proteins*/genetics
Animals ; Heterochromatin/metabolism ; Heterochromatin/genetics ; Genes, Essential ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Protein Binding ; Gene Expression Regulation ; Euchromatin/metabolism ; Euchromatin/genetics ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; Microtubule-Associated Proteins
Czasopismo naukowe
Tytuł:
A global transcriptional activator involved in the iron homeostasis in cyanobacteria.
Autorzy:
Liu LM; Key Laboratory of Marine Biotechnology of Zhejiang Province, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang, China.; School of Life Sciences, Central China Normal University, Wuhan, Hubei, China.
Sun CY; School of Life Sciences, Central China Normal University, Wuhan, Hubei, China.
Xi YC; Key Laboratory of Marine Biotechnology of Zhejiang Province, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang, China.
Lu XH; School of Life Sciences, Central China Normal University, Wuhan, Hubei, China.
Yong CW; Key Laboratory of Marine Biotechnology of Zhejiang Province, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang, China.
Li SQ; Key Laboratory of Marine Biotechnology of Zhejiang Province, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang, China.
Sun QW; Key Laboratory of Marine Biotechnology of Zhejiang Province, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang, China.
Wang XW; Key Laboratory of Marine Biotechnology of Zhejiang Province, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang, China.
Mao YZ; Wuhan Frasergen Bioinformatics Co. Ltd., Wuhan, Hubei, China.
Chen W; Key Laboratory of Marine Biotechnology of Zhejiang Province, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang, China.
Jiang HB; Key Laboratory of Marine Biotechnology of Zhejiang Province, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang, China.; School of Life Sciences, Central China Normal University, Wuhan, Hubei, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, Guangdong, China.
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Źródło:
Science advances [Sci Adv] 2024 Jul 05; Vol. 10 (27), pp. eadl6428. Date of Electronic Publication: 2024 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Iron*/metabolism
Homeostasis*
Gene Expression Regulation, Bacterial*
Synechocystis*/metabolism
Synechocystis*/genetics
Promoter Regions, Genetic*
Bacterial Proteins/metabolism ; Bacterial Proteins/genetics ; Cyanobacteria/metabolism ; Cyanobacteria/genetics ; Gene Expression Profiling
Czasopismo naukowe
Tytuł:
Promoter profiles in plasma CfDNA exhibits a potential utility of predicting the efficacy of neoadjuvant chemotherapy in breast cancer patients.
Autorzy:
Yang X; Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Liu Q; Department of Pathology, The First People's Hospital of Foshan, Foshan, China.
Guo Z; Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Yang X; Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Li K; Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Han B; Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Zhang M; Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Sun M; Department of Primary Public Health, Guangzhou Center for Disease Control and Prevention, Guangzhou, China.; Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention, Guangzhou, China.
Huang L; Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
Cai G; Department of Pathology, The First People's Hospital of Foshan, Foshan, China. .; Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. .
Wu Y; Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China. .
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Źródło:
Breast cancer research : BCR [Breast Cancer Res] 2024 Jul 04; Vol. 26 (1), pp. 112. Date of Electronic Publication: 2024 Jul 04.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/blood
Breast Neoplasms*/pathology
Neoadjuvant Therapy*
Promoter Regions, Genetic*
Biomarkers, Tumor*/blood
Biomarkers, Tumor*/genetics
Cell-Free Nucleic Acids*/blood
Cell-Free Nucleic Acids*/genetics
Humans ; Female ; Middle Aged ; Adult ; Prognosis ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Aged ; Treatment Outcome ; Gene Expression Profiling
Czasopismo naukowe
Tytuł:
Role of ultrasound in predicting telomerase reverse transcriptase (TERT) promoter mutation in follicular thyroid carcinoma.
Autorzy:
Kim MK; Department of Radiology and Center for Imaging Science, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Park H; Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea.
Oh YL; Department of Pathology, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Shin JH; Department of Radiology and Center for Imaging Science, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Kim TH; Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Hahn SY; Department of Radiology and Center for Imaging Science, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. .; Department of Radiology and Center for Imaging Science, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-Gu, Seoul, 06351, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jul 03; Vol. 14 (1), pp. 15323. Date of Electronic Publication: 2024 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Telomerase*/genetics
Promoter Regions, Genetic*
Mutation*
Ultrasonography*/methods
Adenocarcinoma, Follicular*/genetics
Adenocarcinoma, Follicular*/diagnostic imaging
Adenocarcinoma, Follicular*/pathology
Thyroid Neoplasms*/genetics
Thyroid Neoplasms*/diagnostic imaging
Thyroid Neoplasms*/pathology
Humans ; Female ; Male ; Middle Aged ; Adult ; Aged ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Unveiling the oncogenic role of LZTS1 in colorectal cancer.
Autorzy:
Xu Y; Department of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.; Department of Nursing, Daping Hospital, Army Medical University, Chongqing, China.
Pepe D; Laboratory for Disease Mechanisms in Cancer, KU Leuven, Leuven, Belgium.
Yao S; Department of Gastroenterology, Daping Hospital, Army Medical University, Chongqing, China.
Boudhan L; Ludwig Institute for Cancer Research, Brussels, Belgium.; de Duve Institute, UCLouvain, Brussels, Belgium.; Walloon Excellence in Life Sciences and Biotechnology, Brussels, Belgium.
Verbandt S; Digestive Oncology, KU Leuven, Leuven, Belgium.
Pu T; Digestive Oncology, KU Leuven, Leuven, Belgium.
Creemers JWM; Department of Human Genetics, KU Leuven, Leuven, Belgium.
Liu M; Center for Protein and Cell-Based Drugs, Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Tejpar S; Digestive Oncology, KU Leuven, Leuven, Belgium.
He Z; Department of Gastroenterology, Daping Hospital, Army Medical University, Chongqing, China.
Zhu J; Ludwig Institute for Cancer Research, Brussels, Belgium.; de Duve Institute, UCLouvain, Brussels, Belgium.; Walloon Excellence in Life Sciences and Biotechnology, Brussels, Belgium.
Wang Y; Department of Nursing, Daping Hospital, Army Medical University, Chongqing, China.
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Źródło:
Journal of cellular and molecular medicine [J Cell Mol Med] 2024 Jul; Vol. 28 (14), pp. e18441.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/metabolism
Gene Expression Regulation, Neoplastic*
Cell Proliferation*/genetics
Epithelial-Mesenchymal Transition*/genetics
DNA Methylation*/genetics
Promoter Regions, Genetic*/genetics
Cell Movement*/genetics
Humans ; Cell Line, Tumor ; Carcinogenesis/genetics ; Carcinogenesis/pathology ; Signal Transduction ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism ; Oncogenes/genetics ; PTEN Phosphohydrolase/genetics ; PTEN Phosphohydrolase/metabolism
Czasopismo naukowe
Tytuł:
Mecp2 promotes the anti-inflammatory effect of alpinetin via epigenetic modification crosstalk.
Autorzy:
Hu K; Medical College, Hunan University of Medicine, Huaihua, China.
Ma R; Department of General Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Huang M; Medical College, Hunan University of Medicine, Huaihua, China.
Cao X; Medical College, Hunan University of Medicine, Huaihua, China.
Ding Y; Medical College, Hunan University of Medicine, Huaihua, China.
Li Y; Medical College, Hunan University of Medicine, Huaihua, China.
Chen Y; Medical College, Hunan University of Medicine, Huaihua, China.
Xiao L; Medical College, Hunan University of Medicine, Huaihua, China.
Ling S; Department of Cardiology, First Affiliated Hospital, Hunan University of Medicine, Huaihua, China.
Huang Y; Department of Cardiology, First Affiliated Hospital, Hunan University of Medicine, Huaihua, China.
Yin H; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital, Hunan University of Medicine, Huaihua, China.
Tan B; Department of Cardiology, First Affiliated Hospital, Hunan University of Medicine, Huaihua, China.
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Źródło:
Journal of cellular and molecular medicine [J Cell Mol Med] 2024 Jul; Vol. 28 (13), pp. e18510.
Typ publikacji:
Journal Article
MeSH Terms:
Methyl-CpG-Binding Protein 2*/metabolism
Methyl-CpG-Binding Protein 2*/genetics
Flavanones*/pharmacology
Epigenesis, Genetic*/drug effects
Anti-Inflammatory Agents*/pharmacology
Promoter Regions, Genetic*
Animals ; Mice ; RAW 264.7 Cells ; DNA Methylation/drug effects ; Lipopolysaccharides/pharmacology ; Transcription Factor RelA/metabolism ; Sepsis/drug therapy ; Sepsis/genetics ; Sepsis/metabolism ; Macrophages/metabolism ; Macrophages/drug effects ; Inflammation/drug therapy ; Inflammation/pathology ; Inflammation/genetics ; Inflammation/metabolism ; DNA Methyltransferase 3A/metabolism ; Male ; E1A-Associated p300 Protein/metabolism ; Disease Models, Animal ; Mice, Inbred C57BL ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; DNA (Cytosine-5-)-Methyltransferases/genetics
Czasopismo naukowe
Tytuł:
Use of the Saccharomycopsis schoenii MET17 promoter for regulated heterologous gene expression.
Autorzy:
Rij M; Department of Microbiology and Biochemistry, Hochschule Geisenheim University, Von-Lade-Straße 1, 65366, Geisenheim, Germany.
Wendland J; Department of Microbiology and Biochemistry, Hochschule Geisenheim University, Von-Lade-Straße 1, 65366, Geisenheim, Germany. .; Geisenheim Yeast Breeding Center, Hochschule Geisenheim University, Von-Lade-Straße 1, 65366, Geisenheim, Germany. .
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Źródło:
Current genetics [Curr Genet] 2024 Jul 01; Vol. 70 (1), pp. 9. Date of Electronic Publication: 2024 Jul 01.
Typ publikacji:
Journal Article
MeSH Terms:
Promoter Regions, Genetic*
Gene Expression Regulation, Fungal*
Methionine*/metabolism
Methionine*/genetics
Genes, Reporter*
Fungal Proteins/genetics ; Fungal Proteins/metabolism ; beta-Galactosidase/genetics ; beta-Galactosidase/metabolism ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism
Czasopismo naukowe
Tytuł:
Arthropod promoters for genetic control of disease vectors.
Autorzy:
Wudarski J; Department of Biochemistry and Molecular Biology, University of Nevada, Reno, NV, USA.
Aliabadi S; Department of Biochemistry and Molecular Biology, University of Nevada, Reno, NV, USA.
Gulia-Nuss M; Department of Biochemistry and Molecular Biology, University of Nevada, Reno, NV, USA. Electronic address: .
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Źródło:
Trends in parasitology [Trends Parasitol] 2024 Jul; Vol. 40 (7), pp. 619-632. Date of Electronic Publication: 2024 May 31.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Promoter Regions, Genetic*
Vector Borne Diseases*/prevention & control
Vector Borne Diseases*/transmission
Animals ; Humans ; Arthropod Vectors/genetics
Czasopismo naukowe

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