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Tytuł :
In vitro and in vivo GABAA Receptor Interaction of the Propanidid Metabolite 4-(2-[Diethylamino]-2-Oxoethoxy)-3-Methoxy-Benzeneacetic Acid.
Autorzy :
Cenani A; Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, Davis, California, USA.
Brosnan RJ; Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, Davis, California, .
Knych HK; KL Maddy Equine Analytical Chemistry Laboratory, University of California Davis, Davis, California, USA.
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Źródło :
Pharmacology [Pharmacology] 2019; Vol. 103 (1-2), pp. 10-16. Date of Electronic Publication: 2018 Oct 17.
Typ publikacji :
Journal Article
MeSH Terms :
Phenylacetates/*pharmacology
Propanidid/*pharmacology
Receptors, GABA-A/*metabolism
Animals ; GABA-A Receptor Agonists/metabolism ; GABA-A Receptor Agonists/pharmacology ; Humans ; Male ; Mice ; Oocytes/drug effects ; Oocytes/metabolism ; Patch-Clamp Techniques ; Phenylacetates/metabolism ; Propanidid/metabolism ; Receptors, GABA-A/biosynthesis ; Receptors, GABA-A/genetics ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Possible binding sites and interactions of propanidid and AZD3043 within the γ-aminobutyric acid type A receptor (GABA A R).
Autorzy :
Wang S; a School of Chemical and Material Engineering , Jiangnan University , Wuxi 214122 , P.R China.; b Key Laboratory of Nuclear Medicine, Ministry of Health & Jiangsu Key Laboratory of Molecular Nuclear Medicine , Jiangsu Institute of Nuclear Medicine , Wuxi 214063 , P.R. China.
Liu Q; b Key Laboratory of Nuclear Medicine, Ministry of Health & Jiangsu Key Laboratory of Molecular Nuclear Medicine , Jiangsu Institute of Nuclear Medicine , Wuxi 214063 , P.R. China.
Li X; a School of Chemical and Material Engineering , Jiangnan University , Wuxi 214122 , P.R China.; b Key Laboratory of Nuclear Medicine, Ministry of Health & Jiangsu Key Laboratory of Molecular Nuclear Medicine , Jiangsu Institute of Nuclear Medicine , Wuxi 214063 , P.R. China.
Zhao X; a School of Chemical and Material Engineering , Jiangnan University , Wuxi 214122 , P.R China.; b Key Laboratory of Nuclear Medicine, Ministry of Health & Jiangsu Key Laboratory of Molecular Nuclear Medicine , Jiangsu Institute of Nuclear Medicine , Wuxi 214063 , P.R. China.
Qiu L; a School of Chemical and Material Engineering , Jiangnan University , Wuxi 214122 , P.R China.; b Key Laboratory of Nuclear Medicine, Ministry of Health & Jiangsu Key Laboratory of Molecular Nuclear Medicine , Jiangsu Institute of Nuclear Medicine , Wuxi 214063 , P.R. China.
Lin J; b Key Laboratory of Nuclear Medicine, Ministry of Health & Jiangsu Key Laboratory of Molecular Nuclear Medicine , Jiangsu Institute of Nuclear Medicine , Wuxi 214063 , P.R. China.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2018 Nov; Vol. 36 (15), pp. 3926-3937. Date of Electronic Publication: 2017 Nov 29.
Typ publikacji :
Journal Article
MeSH Terms :
Anesthetics, Intravenous/*chemistry
Phenylacetates/*chemistry
Propanidid/*chemistry
Receptors, GABA-A/*chemistry
Binding Sites ; Humans ; Kinetics ; Molecular Docking Simulation ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Substrate Specificity ; Thermodynamics
Czasopismo naukowe
Tytuł :
Synthesis and evaluation of fluorine-substituted phenyl acetate derivatives as ultra-short recovery sedative/hypnotic agents.
Autorzy :
Zhang H; Systems Biology Theme, Huazhong University of Science and Technology, Wuhan, China.
Xu X; Jiangsu Nhwa Pharmaceutical Co., Ltd., Xuzhou, China.
Chen Y; Jiangsu Nhwa Pharmaceutical Co., Ltd., Xuzhou, China.
Qiu Y; Jiangsu Nhwa Pharmaceutical Co., Ltd., Xuzhou, China.
Liu X; Systems Biology Theme, Huazhong University of Science and Technology, Wuhan, China.
Liu BF; Systems Biology Theme, Huazhong University of Science and Technology, Wuhan, China.
Zhang G; Systems Biology Theme, Huazhong University of Science and Technology, Wuhan, China; Jiangsu Nhwa Pharmaceutical Co., Ltd., Xuzhou, China.
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Źródło :
PloS one [PLoS One] 2014 May 05; Vol. 9 (5), pp. e96518. Date of Electronic Publication: 2014 May 05 (Print Publication: 2014).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anesthesia Recovery Period*
Acetates/*chemistry
Fluorine/*chemistry
Hypnotics and Sedatives/*pharmacokinetics
Phenols/*chemistry
Propanidid/*analogs & derivatives
Acetates/pharmacokinetics ; Animals ; Blood-Brain Barrier ; Fluorine/pharmacokinetics ; Half-Life ; Hypnotics and Sedatives/chemistry ; Male ; Mice ; Phenols/pharmacokinetics ; Propanidid/chemistry ; Propanidid/pharmacokinetics ; Rabbits ; Rats ; Rats, Sprague-Dawley ; Time Factors
Czasopismo naukowe
Tytuł :
Intravenous Induction Agents--propanidid.
Autorzy :
Ball C; Geoffrey Kaye Museum of Anaesthetic History.
Westhorpe R
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Źródło :
Anaesthesia and intensive care [Anaesth Intensive Care] 2002 Jun; Vol. 30 (3), pp. 261.
Typ publikacji :
Journal Article
MeSH Terms :
Anesthetics, Intravenous/*administration & dosage
Propanidid/*administration & dosage
Anesthesia, General/methods ; Anesthetics, Intravenous/pharmacology ; Humans ; Propanidid/pharmacology ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
[Anesthesia with propanidid in a liposomal preparation. An experimental study in swine].
Autorzy :
Klockgether-Radke A; Zentrum Anaesthesiologie, Rettungs- und Intensivmedizin, Georg-August-Universität Göttingen.
Kersten J
Schröder T
Stafforst D
Kettler D
Hellige G
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Transliterated Title :
Anästhesie mit Propanidid in liposomaler Zubereitung. Eine experimentelle Studie am Schwein.
Źródło :
Der Anaesthesist [Anaesthesist] 1995 Aug; Vol. 44 (8), pp. 573-80.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anesthesia, Intravenous*
Anesthetics, Intravenous*/administration & dosage
Anesthetics, Intravenous*/adverse effects
Drug Carriers*/adverse effects
Propanidid*/administration & dosage
Propanidid*/adverse effects
Animals ; Catecholamines/blood ; Female ; Hemodynamics/drug effects ; Histamine/blood ; Liposomes/adverse effects ; Male ; Pain Measurement/drug effects ; Pharmaceutical Vehicles/adverse effects ; Polyethylene Glycols/adverse effects ; Preanesthetic Medication ; Swine
Czasopismo naukowe
Tytuł :
[Anesthesiologic efficacy of propanidid as a liposome dispersion. An experimental study with rats].
Autorzy :
Habazettl H; Institut für Chirurgische Forschung, Ludwig-Maximilians-Universität, München.
Vollmar B
Röhrich F
Conzen P
Doenicke A
Baethmann A
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Transliterated Title :
Anästhesiologische Wirksamkeit von Propanidid als Liposomendispersion. Eine experimentelle studie mit ratten.
Źródło :
Der Anaesthesist [Anaesthesist] 1992 Aug; Vol. 41 (8), pp. 448-56.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anesthesia, Intravenous*
Propanidid*
Animals ; Electroencephalography ; Hemodynamics/drug effects ; Hemodynamics/physiology ; Liposomes ; Male ; Polyethylene Glycols/adverse effects ; Rats ; Rats, Inbred Strains ; Solvents/adverse effects
Czasopismo naukowe
Tytuł :
[Comparative evaluation of anesthesia with etomidate and propanidid in patients undergoing electric cardioversion].
Autorzy :
Rzymski S; Zakładu Farmakologii Klinicznej Instytutu Kardiologii AM, Poznaniu.
Szyszka A
Wachowiak H
Kaczmarek J
Mrozikiewicz A
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Transliterated Title :
Porównawcza ocena anestezji etomidatem i propanididem u chorych poddanych kardiowersji elektrycznej.
Źródło :
Polski tygodnik lekarski (Warsaw, Poland : 1960) [Pol Tyg Lek] 1991 Aug 5-19; Vol. 46 (32-34), pp. 592-4.
Typ publikacji :
Comparative Study; English Abstract; Journal Article
MeSH Terms :
Anesthesia*
Electric Countershock*
Etomidate*/adverse effects
Propanidid*/adverse effects
Arrhythmias, Cardiac/*therapy
Pain/*prevention & control
Adult ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
[Intravenous anesthesia for cesarean section. Comparison of propanidid and methohexital].
Autorzy :
Toque Y; Département d'anesthésie-réanimation B, Centre hospitalier et universitaire, Amiens.
Fortaine MR
Delloue M
Lephay A
Khoury A
Ossart M
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Transliterated Title :
Anesthésie intraveineuse pour césarienne. Comparaison du propanidide et du métohexital.
Źródło :
Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression [Agressologie] 1991; Vol. 32 (4), pp. 246-9.
Typ publikacji :
Comparative Study; English Abstract; Journal Article
MeSH Terms :
Cesarean Section*
Anesthesia, Obstetrical/*methods
Methohexital/*administration & dosage
Propanidid/*administration & dosage
Adult ; Apgar Score ; Blood Pressure/drug effects ; Female ; Heart Rate/drug effects ; Humans ; Methohexital/pharmacology ; Pregnancy ; Propanidid/pharmacology ; Retrospective Studies
Czasopismo naukowe
Tytuł :
[Clinico-physiologic characteristics of intravenous sombrevin anesthesia in treating inflammatory diseases of the maxillofacial area].
Autorzy :
Vovk IuV
Suslov VV
Gotsko EV
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Transliterated Title :
Kliniko-fiziologicheskie osobennosti vnutrivennoĭ anestezii sombrevinom pri lechenii vospalitel'nykh zabolevaniĭ cheliustno-litsevoĭ oblasti.
Źródło :
Stomatologiia [Stomatologiia (Mosk)] 1990 Mar-Apr; Vol. 69 (2), pp. 36-8.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Anesthesia, Dental*
Anesthesia, Intravenous*
Propanidid*/adverse effects
Jaw Diseases/*surgery
Adolescent ; Adult ; Aged ; Drug Evaluation ; Face ; Female ; Humans ; Inflammation/surgery ; Male ; Middle Aged ; Time Factors
Czasopismo naukowe
Tytuł :
Subanaesthetic dosage of propanidid as a sedative for dentistry: a controlled clinical trial.
Autorzy :
Cossham PS
Dixon RA
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Źródło :
British journal of anaesthesia [Br J Anaesth] 1973 Apr; Vol. 45 (4), pp. 369-75.
Typ publikacji :
Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms :
Anesthesia, Dental*
Propanidid/*administration & dosage
Adult ; Blood Pressure/drug effects ; Diazepam/adverse effects ; Female ; Heart Rate/drug effects ; Humans ; Male ; Motor Activity ; Movement ; Perception ; Propanidid/adverse effects ; Propanidid/pharmacology ; Pulse ; Salivation ; Shivering ; Thrombophlebitis/chemically induced
Czasopismo naukowe
Tytuł :
Propanidid in obstetric anaesthesia.
Autorzy :
Langrehr D
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Źródło :
Acta anaesthesiologica Belgica [Acta Anaesthesiol Belg] 1974; Vol. 25 (1), pp. 5-12.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anesthesia, Obstetrical*/adverse effects
Propanidid*/administration & dosage
Propanidid*/adverse effects
Propanidid*/pharmacology
Dose-Response Relationship, Drug ; Female ; Halothane ; Hemodynamics/drug effects ; Humans ; Infant, Newborn ; Injections ; Maternal-Fetal Exchange ; Pregnancy ; Respiration/drug effects ; Time Factors
Czasopismo naukowe
Tytuł :
[Complications during epontal anesthesia].
Autorzy :
Dannemann H
Lübke P
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Transliterated Title :
Komplikationen während Narkosen mit Epontol.
Źródło :
Zeitschrift fur praktische Anasthesie und Wiederbelebung [Z Prakt Anasth] 1970 Aug; Vol. 5 (4), pp. 273-7.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroleptanalgesia/*adverse effects
Propanidid/*adverse effects
Adolescent ; Adult ; Age Factors ; Aged ; Child ; Child, Preschool ; Drug Hypersensitivity ; Drug Tolerance ; Female ; Heart/drug effects ; Humans ; Injections, Intravenous ; Male ; Middle Aged ; Premedication ; Propanidid/administration & dosage ; Propanidid/pharmacology
Czasopismo naukowe
Tytuł :
[Use of propanidid in perfusion in children aged 0 to 8 years].
Autorzy :
Sauvage MR
Krivosic R
Calmes MO
Zimmer R
Gauthier-Lafaye JP
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Transliterated Title :
Utilisation du propanidide en perfusion chez l'enfant de 0 à 8 ans
Źródło :
Anesthesie, analgesie, reanimation [Anesth Analg (Paris)] 1974 Mar-Apr; Vol. 31 (2), pp. 237-47.
Typ publikacji :
Journal Article
MeSH Terms :
Propanidid*/administration & dosage
Propanidid*/adverse effects
Anesthesia, Intravenous/*methods
Age Factors ; Cardiovascular System/drug effects ; Child ; Child, Preschool ; Cough/chemically induced ; Digestive System/drug effects ; Hiccup/chemically induced ; Humans ; Infant ; Infant, Newborn ; Laryngismus/chemically induced ; Postoperative Care ; Preanesthetic Medication ; Respiratory System/drug effects ; Tremor/chemically induced
Czasopismo naukowe
Tytuł :
[Arterial blood gas analyses following administration of three short-acting i.v. hypnotics (propanidid, etomidate, methohexitone) (author's transl)].
Autorzy :
Doenicke A
Wagner E
Beetz KH
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Transliterated Title :
Blutgasanalysen (arteriell) nach drei kurzwirkenden i. v. Hypnotica (Propanidid, Etomidate und Methohexital.
Źródło :
Der Anaesthesist [Anaesthesist] 1973 Aug; Vol. 22 (8), pp. 353-6.
Typ publikacji :
Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms :
Acid-Base Equilibrium/*drug effects
Hypnotics and Sedatives/*pharmacology
Imidazoles/*pharmacology
Methohexital/*pharmacology
Oxygen/*blood
Propanidid/*pharmacology
Adult ; Anesthesia, Intravenous ; Anesthetics/administration & dosage ; Benzyl Compounds/pharmacology ; Blood ; Carbon Dioxide/blood ; Clinical Trials as Topic ; Humans ; Hydrogen-Ion Concentration ; Male ; Methohexital/administration & dosage ; Methohexital/adverse effects ; Partial Pressure ; Propanidid/administration & dosage ; Propanidid/adverse effects ; Respiration/drug effects ; Respiration, Artificial ; Time Factors
Czasopismo naukowe
Tytuł :
[Errors and hazards. Propanidid for the induction of neuroleptoanalgesia].
Autorzy :
Doenicke A
Schmidinger S
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Transliterated Title :
Fehler und Gefahren. Propanidid zur Einleitung der Neuroleptanalgesie.
Źródło :
Der Anaesthesist [Anaesthesist] 1970 Dec; Vol. 19 (12), pp. 479-82.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroleptanalgesia*
Propanidid/*pharmacology
Abdomen/surgery ; Histamine H1 Antagonists/therapeutic use ; Histamine Release/drug effects ; Humans ; Intubation ; Liver Diseases/surgery ; Male ; Preanesthetic Medication ; Propanidid/administration & dosage ; Propanidid/adverse effects ; Protein Binding/drug effects
Czasopismo naukowe
Tytuł :
[Trials of propanidid in anesthesia for bronchial endoscopy in infants and children].
Autorzy :
Alphonsi R
Pannetier A
Camboulives J
Unal D
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Transliterated Title :
Essai du propanidide en anesthésie pour endoscopie bronchique chez l'enfant et le nourrisson.
Źródło :
Annales de l'anesthesiologie francaise [Ann Anesthesiol Fr] 1979; Vol. 20 (4), pp. 298-302.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Propanidid*/administration & dosage
Propanidid*/adverse effects
Anesthesia, Intravenous/*methods
Bronchoscopy/*methods
Anesthesia, Intravenous/adverse effects ; Blood Pressure/drug effects ; Carbon Dioxide/blood ; Child ; Child, Preschool ; Heart Rate/drug effects ; Humans ; Infant ; Infusions, Parenteral ; Oxygen/blood ; Preanesthetic Medication ; Respiration/drug effects
Czasopismo naukowe
Tytuł :
Propanidid (epontol for induction of general anaesthesia in Caesarean section.
Autorzy :
Gran L
Maltau JM
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Źródło :
Der Anaesthesist [Anaesthesist] 1971 Jul; Vol. 20 (7), pp. 247-9.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anesthesia, Obstetrical*
Cesarean Section*
Propanidid*/administration & dosage
Propanidid*/pharmacology
Anesthesia, General ; Female ; Humans ; Infant, Newborn ; Pregnancy ; Respiration/drug effects ; Thiopental
Czasopismo naukowe
Tytuł :
[Dissociative analgesia in electric cardioversion].
Autorzy :
Pappalettera N
Rognoni G
Gatti G
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Transliterated Title :
L'analgesia dissociativa nella cardioversione elettrica.
Źródło :
Minerva anestesiologica [Minerva Anestesiol] 1977 Sep; Vol. 43 (9), pp. 501-3.
Typ publikacji :
Journal Article
MeSH Terms :
Ketamine*/administration & dosage
Ketamine*/adverse effects
Propanidid*/administration & dosage
Propanidid*/adverse effects
Anesthesia, Intravenous/*methods
Electric Countershock/*methods
Anesthesia, Intravenous/adverse effects ; Drug Evaluation ; Humans ; Respiration/drug effects
Czasopismo naukowe

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