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Tytuł :
Comparative Analysis of Genomic Alterations across Castration Sensitive and Castration Resistant Prostate Cancer via Circulating Tumor DNA Sequencing.
Autorzy :
Fan L; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Fei X; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zhu Y; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Pan J; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Sha J; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chi C; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Gong Y; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Du X; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zhou L; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Dong B; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Xue W; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
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Źródło :
The Journal of urology [J Urol] 2021 Feb; Vol. 205 (2), pp. 461-469. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Sequence Analysis, DNA*
Circulating Tumor DNA/*blood
Circulating Tumor DNA/*genetics
Prostatic Neoplasms/*blood
Prostatic Neoplasms/*genetics
Aged ; Androgen Antagonists/therapeutic use ; Genomics ; Humans ; Male ; Middle Aged ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms, Castration-Resistant/blood ; Prostatic Neoplasms, Castration-Resistant/genetics ; Retrospective Studies
Czasopismo naukowe
Tytuł :
PROACTA: a survey on the actual attitude of the Italian radiation oncologists in the management and prescription of hormonal therapy in prostate cancer patients.
Autorzy :
Fersino S; Radiation Oncology Department, Azienda Provinciale per i Servizi Sanitari, Ospedale S.Chiara, Largo Medaglie d'oro, 9, 38122, Trento, Italy. .
Borghesi S; Radiotherapy Unit- Ospedale S. Donato e Santa Maria alla Gruccia, Azienda USL Toscana Sud, Arezzo, Italy.
Jereczek-Fossa BA; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.; Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, Milan, Italy.
Arcangeli S; UOC Radioterapia ASST Monza, Università di Milano, Bicocca, Italy.
Mortellaro G; Department of Radiation Oncology, ARNAS Ospedale Civico, Palermo, Italy.
Magrini SM; Department of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
Alongi F; Advanced Radiation Oncology Department, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar-Verona, Italy.; University of Brescia, Brescia, Italy.
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Corporate Authors :
Uro-Oncology study group of Italian association of Radiotherapy and Clinical Oncology (AIRO)
Źródło :
La Radiologia medica [Radiol Med] 2021 Mar; Vol. 126 (3), pp. 460-465. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article
MeSH Terms :
Attitude of Health Personnel*
Radiation Oncologists*
Androgen Antagonists/*therapeutic use
Antineoplastic Agents, Hormonal/*therapeutic use
Health Care Surveys/*statistics & numerical data
Prostatic Neoplasms/*drug therapy
Androstenes/therapeutic use ; Combined Modality Therapy/methods ; Gonadotropin-Releasing Hormone/agonists ; Humans ; Italy ; Male ; Phenylthiohydantoin/analogs & derivatives ; Phenylthiohydantoin/therapeutic use ; Prostatectomy ; Prostatic Neoplasms/radiotherapy ; Prostatic Neoplasms/surgery ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Prostatic Neoplasms, Castration-Resistant/radiotherapy ; Risk Factors ; Salvage Therapy/methods
Czasopismo naukowe
Tytuł :
Obesity is Associated with Longer Survival Independent of Sarcopenia and Myosteatosis in Metastatic and/or Castrate-Resistant Prostate Cancer.
Autorzy :
Xu MC; Vanderbilt University School of Medicine, Nashville, Tennessee.
Huelster HL; Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee.
Hatcher JB; Vanderbilt University School of Medicine, Nashville, Tennessee.
Avulova S; Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee.
Stocks BT; Vanderbilt University School of Medicine, Nashville, Tennessee.
Glaser ZA; Vanderbilt University School of Medicine, Nashville, Tennessee.
Moses KA; Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee.
Silver HJ; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
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Źródło :
The Journal of urology [J Urol] 2021 Mar; Vol. 205 (3), pp. 800-805. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Obesity/*complications
Prostatic Neoplasms/*pathology
Sarcopenia/*complications
Adipose Tissue/diagnostic imaging ; Aged ; Aged, 80 and over ; Humans ; Male ; Middle Aged ; Muscle, Skeletal/diagnostic imaging ; Neoplasm Metastasis ; Neoplasm Staging ; Obesity/diagnostic imaging ; Prostatic Neoplasms, Castration-Resistant/pathology ; Retrospective Studies ; Sarcopenia/diagnostic imaging ; Survival Rate ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Treating Prostate Cancer by Antibody-Drug Conjugates.
Autorzy :
Rosellini M; Division of Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Santoni M; Oncology Unit, Macerata Hospital, 62100 Macerata, Italy.
Mollica V; Division of Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Rizzo A; Division of Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Cimadamore A; Section of Pathological Anatomy, School of Medicine, United Hospitals, Polytechnic University of the Marche Region, 60126 Ancona, Italy.
Scarpelli M; Section of Pathological Anatomy, School of Medicine, United Hospitals, Polytechnic University of the Marche Region, 60126 Ancona, Italy.
Storti N; Direzione Sanitaria Azienda Sanitaria Unica Regionale, 60122 Ancona, Italy.
Battelli N; Oncology Unit, Macerata Hospital, 62100 Macerata, Italy.
Montironi R; Section of Pathological Anatomy, School of Medicine, United Hospitals, Polytechnic University of the Marche Region, 60126 Ancona, Italy.
Massari F; Division of Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 04; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents, Immunological/*therapeutic use
Immunoconjugates/*therapeutic use
Prostatic Neoplasms/*drug therapy
Animals ; Antineoplastic Agents, Immunological/pharmacology ; Biomarkers, Tumor ; Clinical Trials as Topic ; Disease Management ; Disease Susceptibility ; Humans ; Immunoconjugates/pharmacology ; Male ; Molecular Targeted Therapy ; Prognosis ; Prostatic Neoplasms/etiology ; Prostatic Neoplasms/mortality ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Prostatic Neoplasms, Castration-Resistant/etiology ; Prostatic Neoplasms, Castration-Resistant/mortality ; Prostatic Neoplasms, Castration-Resistant/pathology ; Standard of Care ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Contemporary management of advanced prostate cancer: an evolving landscape.
Autorzy :
Khanna A; Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
O'Connor LP; Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Murthy PB; Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Bryk DJ; Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Fascelli M; Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Ericson K; Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Yerram NK; Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Haywood SC; Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Abouassaly R; Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
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Źródło :
Clinical advances in hematology & oncology : H&O [Clin Adv Hematol Oncol] 2021 Feb; Vol. 19 (2), pp. 108-118.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Therapies, Investigational*
Adenocarcinoma/*therapy
Prostatic Neoplasms/*therapy
Adenocarcinoma/diagnostic imaging ; Adenocarcinoma/secondary ; Androstenes/therapeutic use ; Benzamides/therapeutic use ; Clinical Trials as Topic ; Combined Modality Therapy ; Diagnostic Imaging/methods ; Disease Management ; Docetaxel/therapeutic use ; Humans ; Male ; Multicenter Studies as Topic ; Nitriles/therapeutic use ; Phenylthiohydantoin/therapeutic use ; Precision Medicine ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms, Castration-Resistant/diagnostic imaging ; Prostatic Neoplasms, Castration-Resistant/therapy ; Radiotherapy, Adjuvant ; Radium/therapeutic use ; Taxoids/therapeutic use
Czasopismo naukowe
Tytuł :
Exosomes Promote the Transition of Androgen-Dependent Prostate Cancer Cells into Androgen-Independent Manner Through Up-Regulating the Heme Oxygenase-1.
Autorzy :
Zhang Y; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangzhou Key Laboratory of Inflammatory and Immune Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Chen B; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangzhou Key Laboratory of Inflammatory and Immune Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Xu N; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Xu P; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangzhou Key Laboratory of Inflammatory and Immune Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Lin W; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangzhou Key Laboratory of Inflammatory and Immune Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Liu C; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangzhou Key Laboratory of Inflammatory and Immune Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Huang P; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Guangzhou Key Laboratory of Inflammatory and Immune Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Jan 12; Vol. 16, pp. 315-327. Date of Electronic Publication: 2021 Jan 12 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Androgens/*pharmacology
Exosomes/*metabolism
Heme Oxygenase-1/*metabolism
Prostatic Neoplasms/*pathology
Up-Regulation/*drug effects
Animals ; Cell Line, Tumor ; Disease Progression ; Exosomes/ultrastructure ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Mice, Inbred NOD ; Mice, SCID ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms, Castration-Resistant/genetics ; Prostatic Neoplasms, Castration-Resistant/pathology ; Receptors, Androgen/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
4,4'-Diisothiocyanatostilbene-2,2'-disulfonate modulates voltage-gated K current and influences cell cycle arrest in androgen sensitive and insensitive human prostate cancer cell lines.
Autorzy :
George K; Department of Biomedical Engineering, Chennai Institute of Technology, Chennai, India.; Bio Engineering Lab, Department of Electronics and Instrumentation Engineering, Annamalai University, Annamalai Nagar, India.
Thomas NS; Department of Biochemistry and Biotechnology, Annamalai University, Annamalai Nagar, India.
Malathi R; Bio Engineering Lab, Department of Electronics and Instrumentation Engineering, Annamalai University, Annamalai Nagar, India.
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Źródło :
Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Jun; Vol. 30 (5), pp. 358-369. Date of Electronic Publication: 2020 Apr 01.
Typ publikacji :
Journal Article
MeSH Terms :
Prostatic Neoplasms*/metabolism
Prostatic Neoplasms*/pathology
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid/*pharmacology
Antineoplastic Agents/*pharmacology
Cell Cycle Checkpoints/*drug effects
Potassium Channel Blockers/*pharmacology
Potassium Channels, Voltage-Gated/*antagonists & inhibitors
Receptors, Androgen/*metabolism
Apoptosis/drug effects ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Humans ; Male ; Membrane Potentials/drug effects ; PC-3 Cells ; Patch-Clamp Techniques ; Potassium Channels, Voltage-Gated/metabolism ; Prostate/drug effects ; Prostate/metabolism ; Prostatic Neoplasms, Castration-Resistant/metabolism ; Prostatic Neoplasms, Castration-Resistant/pathology ; Tetraethylammonium/pharmacology
Czasopismo naukowe
Tytuł :
Bisphosphonates or RANK-ligand-inhibitors for men with prostate cancer and bone metastases: a network meta-analysis.
Autorzy :
Jakob T; Cochrane Haematology, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Tesfamariam YM; Cochrane Haematology, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Macherey S; University of Cologne, Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cochrane Haematological Malignancies, Cologne, Germany.
Kuhr K; Institute of Medical Statistics and Computational Biology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Adams A; Institute of Medical Statistics and Computational Biology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Monsef I; Cochrane Haematology, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Heidenreich A; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Department of Urology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Skoetz N; Cochrane Cancer, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
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Źródło :
The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2020 Dec 03; Vol. 12. Cochrane AN: CD013020. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Bone Density Conservation Agents/*therapeutic use
Bone Neoplasms/*drug therapy
Bone Neoplasms/*secondary
Denosumab/*therapeutic use
Diphosphonates/*therapeutic use
Prostatic Neoplasms/*pathology
RANK Ligand/*antagonists & inhibitors
Adult ; Alendronate/adverse effects ; Alendronate/therapeutic use ; Antineoplastic Agents, Hormonal/therapeutic use ; Bisphosphonate-Associated Osteonecrosis of the Jaw/etiology ; Bone Density Conservation Agents/adverse effects ; Clodronic Acid/adverse effects ; Clodronic Acid/therapeutic use ; Denosumab/adverse effects ; Diphosphonates/adverse effects ; Etidronic Acid/adverse effects ; Etidronic Acid/therapeutic use ; Humans ; Male ; Network Meta-Analysis ; Pamidronate/adverse effects ; Pamidronate/therapeutic use ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms, Castration-Resistant/pathology ; Quality of Life ; Randomized Controlled Trials as Topic ; Risedronic Acid/adverse effects ; Risedronic Acid/therapeutic use ; Zoledronic Acid/adverse effects ; Zoledronic Acid/therapeutic use
Czasopismo naukowe
Tytuł :
EGFR as a stable marker of prostate cancer dissemination to bones.
Autorzy :
Nastały P; Laboratory of Translational Oncology, Institute of Medical Biotechnology and Experimental Oncology, Medical University of Gdańsk, Gdańsk, Poland.; FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology (IFOM), Milan, Italy.
Stoupiec S; Department of Tumour Biology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Popęda M; Laboratory of Translational Oncology, Institute of Medical Biotechnology and Experimental Oncology, Medical University of Gdańsk, Gdańsk, Poland.
Smentoch J; Laboratory of Translational Oncology, Institute of Medical Biotechnology and Experimental Oncology, Medical University of Gdańsk, Gdańsk, Poland.
Schlomm T; Department of Urology, Charité University Hospital Berlin, Berlin, Germany.
Morrissey C; Department of Urology, University of Washington, Seattle, WA, USA.
Żaczek AJ; Laboratory of Translational Oncology, Institute of Medical Biotechnology and Experimental Oncology, Medical University of Gdańsk, Gdańsk, Poland.
Beyer B; Martini-Clinic, Prostate Cancer Center and Section for Translational Prostate Cancer Research at the Clinic of Urology at University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Tennstedt P; Martini-Clinic, Prostate Cancer Center and Section for Translational Prostate Cancer Research at the Clinic of Urology at University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Graefen M; Martini-Clinic, Prostate Cancer Center and Section for Translational Prostate Cancer Research at the Clinic of Urology at University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Eltze E; Institute of Pathology Saarbruecken-Rastpfuhl, Saarbruecken, Germany.
Maiuri P; FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology (IFOM), Milan, Italy.
Semjonow A; Department of Urology, Prostate Center University Clinic Münster, Münster, Germany.
Pantel K; Department of Tumour Biology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Brandt B; University Medical Centre Schleswig-Holstein, Kiel, Germany.
Bednarz-Knoll N; Laboratory of Translational Oncology, Institute of Medical Biotechnology and Experimental Oncology, Medical University of Gdańsk, Gdańsk, Poland. .; Department of Tumour Biology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany. .
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Źródło :
British journal of cancer [Br J Cancer] 2020 Dec; Vol. 123 (12), pp. 1767-1774. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*metabolism
Bone Neoplasms/*secondary
Neoplastic Cells, Circulating/*metabolism
Prostatic Neoplasms/*pathology
Biomarkers, Tumor/genetics ; Bone Neoplasms/mortality ; Cell Movement ; Collagen Type I/genetics ; Epithelial-Mesenchymal Transition ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Feasibility Studies ; Flow Cytometry ; Humans ; Immunohistochemistry ; Male ; Neoplastic Cells, Circulating/pathology ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/mortality ; Prostatic Neoplasms, Castration-Resistant/metabolism ; Prostatic Neoplasms, Castration-Resistant/mortality ; Prostatic Neoplasms, Castration-Resistant/pathology ; Vimentin/metabolism
Czasopismo naukowe
Tytuł :
Population-based Assessment of Intermittent Androgen Deprivation Therapy Utilization for Relapsed, Nonmetastatic, Hormone-sensitive Adenocarcinoma of the Prostate.
Autorzy :
Janzen BW; Postgraduate Medical Education.
Ong A; Section of Radiation Oncology.
Penner M; Canadian Mennonite University, Winnipeg, MB, Canada.
Koul R; Section of Radiation Oncology.
Dubey A; Section of Radiation Oncology.
Ahmed S; Section of Radiation Oncology.
Bashir B; Section of Radiation Oncology.
Chowdhury A; Section of Radiation Oncology.
Dawe DE; Section of Hematology/Oncology, Department of Internal Medicine.; Section of Urology, Department of Surgery, Max Rady College of Medicine.
Nayak J; Section of Urology, Department of Surgery, Max Rady College of Medicine.
Kim JO; Section of Radiation Oncology.; Research Institute in Hematology and Oncology, CancerCare Manitoba, University of Manitoba.
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Źródło :
American journal of clinical oncology [Am J Clin Oncol] 2020 Dec 01; Vol. 43 (12), pp. 865-871.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma/*drug therapy
Androgen Antagonists/*therapeutic use
Antineoplastic Agents, Hormonal/*therapeutic use
Prostatic Neoplasms/*drug therapy
Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Adenocarcinoma/therapy ; Aged ; Aged, 80 and over ; Humans ; Kallikreins/blood ; Male ; Manitoba/epidemiology ; Marital Status ; Middle Aged ; Neoplasm Recurrence, Local/drug therapy ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/mortality ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/therapy ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Prostatic Neoplasms, Castration-Resistant/pathology ; Radiation Oncologists ; Retrospective Studies ; Survival Analysis
Czasopismo naukowe
Tytuł :
Doublecortin Expression in Prostate Adenocarcinoma and Neuroendocrine Tumors.
Autorzy :
Tabrizi S; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts. Electronic address: .
Alshalalfa M; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts; Department of Radiation Oncology, University of California, San Francisco, California.
Mahal BA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.
Davicioni E; Decipher Biosciences, San Diego, California.
Liu Y; Decipher Biosciences, San Diego, California.
Mouw KW; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.
Feng F; Department of Radiation Oncology, University of California, San Francisco, California.
Nguyen PL; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.
Muralidhar V; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.
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Źródło :
International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2020 Nov 15; Vol. 108 (4), pp. 936-940. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*metabolism
Microtubule-Associated Proteins/*metabolism
Neoplasm Proteins/*metabolism
Neuroendocrine Tumors/*metabolism
Neuropeptides/*metabolism
Prostatic Neoplasms/*metabolism
Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Confidence Intervals ; Humans ; Linear Models ; Male ; Neuroendocrine Tumors/mortality ; Neuroendocrine Tumors/pathology ; Prostate/metabolism ; Prostatic Neoplasms/mortality ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms, Castration-Resistant/metabolism ; Prostatic Neoplasms, Castration-Resistant/mortality ; Prostatic Neoplasms, Castration-Resistant/pathology ; Statistics, Nonparametric
Czasopismo naukowe
Tytuł :
Cellular growth factors as prospective therapeutic targets for combination therapy in androgen independent prostate cancer (AIPC).
Autorzy :
Jonnalagadda B; Department of Biomedical Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
Arockiasamy S; Department of Biomedical Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, India. Electronic address: .
Krishnamoorthy S; Department of Urology, Sri Ramachandra Medical Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118208. Date of Electronic Publication: 2020 Aug 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Prostatic Neoplasms, Castration-Resistant/*drug therapy
Receptors, Androgen/*metabolism
Androgens/metabolism ; Combined Modality Therapy/methods ; Disease Progression ; Drug Therapy, Combination/methods ; Humans ; Intercellular Signaling Peptides and Proteins/metabolism ; Male ; Prospective Studies ; Prostate/metabolism ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms, Castration-Resistant/metabolism ; Receptors, Androgen/drug effects ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Three-month early change in prostate-specific antigen levels as a predictive marker for overall survival during hormonal therapy for metastatic hormone-sensitive prostate cancer.
Autorzy :
Nakanishi S; Department of Urology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan. .
Goya M; Department of Urology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
Tamaki M; Naha City Hospital, Naha, Okinawa, Japan.
Oshiro T; Naha City Hospital, Naha, Okinawa, Japan.
Saito S; Department of Urology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
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Źródło :
BMC research notes [BMC Res Notes] 2021 Jun 03; Vol. 14 (1), pp. 227. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms, Castration-Resistant*/drug therapy
Androgen Antagonists/therapeutic use ; Hormones ; Humans ; Male ; Neoplasm Grading ; Prostate-Specific Antigen ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Editorial Comment to Regional and facility disparities in androgen deprivation therapy for prostate cancer from a multi-institutional Japan-wide database.
Autorzy :
Hatakeyama S; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.
Ohyama C; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.
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Źródło :
International journal of urology : official journal of the Japanese Urological Association [Int J Urol] 2021 May; Vol. 28 (5), pp. 591-592. Date of Electronic Publication: 2021 Mar 04.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms, Castration-Resistant*/drug therapy
Androgen Antagonists/adverse effects ; Androgens ; Antineoplastic Agents, Hormonal/therapeutic use ; Humans ; Japan/epidemiology ; Male
Opinia redakcyjna
Tytuł :
Systematic Literature Review of the Epidemiology of Advanced Prostate Cancer and Associated Homologous Recombination Repair Gene Alterations.
Autorzy :
Shore N; Carolina Urologic Research Center , Myrtle Beach, South Carolina.
Oliver L; Adelphi Values PROVE , Manchester, UK.
Shui I; Merck & Co.Inc., Kenilworth, New Jersey.
Gayle A; AstraZeneca , Cambridge, UK.
Wong OY; Adelphi Values PROVE , Manchester, UK.
Kim J; Merck & Co.Inc., Kenilworth, New Jersey.
Payne S; AstraZeneca , Cambridge, UK.
Amin S; AstraZeneca , Cambridge, UK.
Ghate S; Merck & Co.Inc., Kenilworth, New Jersey.
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Źródło :
The Journal of urology [J Urol] 2021 Apr; Vol. 205 (4), pp. 977-986. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Recombinational DNA Repair*
Biomarkers, Tumor/*genetics
Prostatic Neoplasms, Castration-Resistant/*epidemiology
Prostatic Neoplasms, Castration-Resistant/*genetics
Circulating Tumor DNA/genetics ; DNA Mutational Analysis ; Disease Progression ; Genetic Predisposition to Disease ; Germ-Line Mutation ; Humans ; Male ; Neoplasm Metastasis ; Prevalence ; Prognosis ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms, Castration-Resistant/pathology
Czasopismo naukowe
Tytuł :
Selecting Patients with Favorable Risk, Grade Group 2 Prostate Cancer for Active Surveillance-Does Magnetic Resonance Imaging Have a Role?
Autorzy :
Stonier T; Department of Surgery (Urology Service), Memorial Sloan Kettering Cancer Center, New York, New York.; St George's Hospital, London, UK.
Tin AL; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Sjoberg DD; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Jibara G; Department of Surgery (Urology Service), Memorial Sloan Kettering Cancer Center, New York, New York.
Vickers AJ; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Fine S; Department of Surgery (Urology Service), Memorial Sloan Kettering Cancer Center, New York, New York.
Eastham J; Department of Surgery (Urology Service), Memorial Sloan Kettering Cancer Center, New York, New York.
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Źródło :
The Journal of urology [J Urol] 2021 Apr; Vol. 205 (4), pp. 1063-1068. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Patient Selection*
Prostatic Neoplasms/*diagnostic imaging
Prostatic Neoplasms/*surgery
Aged ; Biopsy ; Humans ; Male ; Middle Aged ; Multiparametric Magnetic Resonance Imaging ; Neoplasm Grading ; Neoplasm Staging ; Prostatectomy ; Prostatic Neoplasms/pathology ; Retrospective Studies ; Risk Factors ; Watchful Waiting
Czasopismo naukowe
Tytuł :
Oncologic Outcomes after Localized Prostate Cancer Treatment: Associations with Pretreatment Prostate Magnetic Resonance Imaging Findings.
Autorzy :
Wibmer AG; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Chaim J; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Lakhman Y; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Lefkowitz RA; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Nincevic J; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Nikolovski I; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Sala E; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Gonen M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Carlsson SV; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Urology, Sahlgrenska Academy at University of Gothenburg, Institute of Clinical Sciences, Gothenburg, Sweden.
Fine SW; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Zelefsky MJ; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Scardino P; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Hricak H; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Vargas HA; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Źródło :
The Journal of urology [J Urol] 2021 Apr; Vol. 205 (4), pp. 1055-1062. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Magnetic Resonance Imaging/*methods
Prostatic Neoplasms/*diagnostic imaging
Prostatic Neoplasms/*therapy
Adult ; Aged ; Aged, 80 and over ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness ; Prognosis ; Prostatectomy ; Prostatic Neoplasms/mortality ; Radiotherapy ; Retrospective Studies ; Survival Rate
Czasopismo naukowe
Tytuł :
[TITAN study: evaluation of apalutamide in patients with metastatic hormone-sensitive prostate cancer - Treatment of metastatic hormone-sensitive prostate cancer (mHSPC)].
Autorzy :
Merseburger AS; Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Urology, Lübeck.
Suttmann H; Urologikum Hamburg, Standort Eppendorf, Hamburg.
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Transliterated Title :
TITAN-Studie – Evaluation von Apalutamid bei Patienten mit metastasiertem hormonsensitivem Prostatakarzinom.
Źródło :
Aktuelle Urologie [Aktuelle Urol] 2021 Apr; Vol. 52 (2), pp. 155-160. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms, Castration-Resistant*
Androgen Antagonists/adverse effects ; Hormones ; Humans ; Male ; Quality of Life ; Thiohydantoins
Czasopismo naukowe
Tytuł :
A novel tool for improving the interpretation of isotope bone scans in metastatic prostate cancer.
Autorzy :
Alshehri AHD; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Cancer Research and Cell Biology, Belfast, UK.; Nuclear Medicine department, Northern Ireland Cancer Centre, Belfast Health and Social Care Trust, Belfast, UK.
Osman SOS; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Cancer Research and Cell Biology, Belfast, UK.; Radiotherapy Physics, Northern Ireland Cancer Centre, Belfast Health and Social Care Trust, Belfast, UK.
Prise KM; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Cancer Research and Cell Biology, Belfast, UK.
Campfield C; Nuclear Medicine department, Northern Ireland Cancer Centre, Belfast Health and Social Care Trust, Belfast, UK.
Turner PG; Clinical Oncology, Northern Ireland Cancer Centre, Belfast Health and Social Care Trust, Belfast, UK.
Jain SFP; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Cancer Research and Cell Biology, Belfast, UK.; Clinical Oncology, Northern Ireland Cancer Centre, Belfast Health and Social Care Trust, Belfast, UK.
O'Sullivan JM; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Cancer Research and Cell Biology, Belfast, UK.; Clinical Oncology, Northern Ireland Cancer Centre, Belfast Health and Social Care Trust, Belfast, UK.
Cole AJ; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Cancer Research and Cell Biology, Belfast, UK.; Clinical Oncology, Northern Ireland Cancer Centre, Belfast Health and Social Care Trust, Belfast, UK.
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Źródło :
The British journal of radiology [Br J Radiol] 2020 Nov 01; Vol. 93 (1115), pp. 20200775. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Software Design*
Bone Neoplasms/*diagnostic imaging
Bone Neoplasms/*secondary
Bone and Bones/*diagnostic imaging
Prostatic Neoplasms/*pathology
Aged ; Aged, 80 and over ; Bone Neoplasms/pathology ; Bone Neoplasms/radiotherapy ; Etidronic Acid ; Humans ; Male ; Middle Aged ; Organotechnetium Compounds ; Prostatic Neoplasms, Castration-Resistant/pathology ; Radiopharmaceuticals ; Regression Analysis ; Tumor Burden ; Urinary Bladder/diagnostic imaging
Czasopismo naukowe
Tytuł :
Identification of crucial genes and pathways associated with prostate cancer in multiple databases.
Autorzy :
Guo H; School of Clinical Medicine, Bengbu Medical College, Bengbu, China.
Zhang Z; School of Clinical Medicine, Bengbu Medical College, Bengbu, China.
Wang Y; School of Clinical Medicine, Bengbu Medical College, Bengbu, China.
Xue S; Department of Urology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
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Źródło :
The Journal of international medical research [J Int Med Res] 2021 Jun; Vol. 49 (6), pp. 3000605211016624.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Prostatic Neoplasms*/diagnosis
Prostatic Neoplasms*/genetics
Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Humans ; Male ; Neoplasm Proteins/genetics ; Neoplasm Recurrence, Local ; Receptors for Activated C Kinase
Czasopismo naukowe

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