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Wyszukujesz frazę ""Proteasome Endopeptidase Complex"" wg kryterium: Temat


Tytuł:
Ubiquitin-proteasome system regulation of a key gene regulatory factor, Paf1C.
Autorzy:
Barman P; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.
Ferdoush J; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.
Kaja A; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.
Chakraborty P; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.
Uprety B; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.
Bhaumik R; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.
Bhaumik R; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.
Bhaumik SR; Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA. Electronic address: .
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Źródło:
Gene [Gene] 2024 Feb 05; Vol. 894, pp. 148004. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/genetics
Proteasome Endopeptidase Complex*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Humans ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Ubiquitin/genetics ; Ubiquitin/metabolism ; RNA-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł:
Proteasome-associated autoinflammatory syndrome 2 in a neonate.
Autorzy:
Zhang F; Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Ma N; Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Zhang L; Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Xia B; Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Yang R; Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Hu Y; Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
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Źródło:
Pediatric dermatology [Pediatr Dermatol] 2024 Jan-Feb; Vol. 41 (1), pp. 166-168. Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Case Reports; Letter
MeSH Terms:
Proteasome Endopeptidase Complex*/genetics
Proteasome Endopeptidase Complex*/metabolism
Infant, Newborn ; Humans ; Syndrome ; Mutation
Raport
Tytuł:
Millmeter-wave irradiation regulates mRNA-expression and the ubiquitin-proteasome system in wheat exposed to flooding stress.
Autorzy:
Komatsu S; Department of Applied Chemistry and Food Science, Fukui University of Technology, Fukui 910-8505, Japan. Electronic address: .
Nishiuchi T; Research Center for Experimental Modeling of Human Disease, Kanazawa University, Kanazawa 920-8640, Japan.
Furuya T; Research Center for Development of Far-Infrared Region, University of Fukui, Fukui 910-8507, Japan.
Tani M; Research Center for Development of Far-Infrared Region, University of Fukui, Fukui 910-8507, Japan.
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Źródło:
Journal of proteomics [J Proteomics] 2024 Mar 15; Vol. 294, pp. 105073. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/metabolism
Histones*/metabolism
Triticum/metabolism ; Plant Roots/metabolism ; Stress, Physiological ; Ubiquitin/metabolism ; Glycine max ; Plant Proteins/metabolism ; Proteome/metabolism ; Proteomics/methods ; Nuclear Proteins/metabolism ; RNA, Messenger/metabolism ; Floods ; Gene Expression Regulation, Plant
Czasopismo naukowe
Tytuł:
Proteotoxic stress and the ubiquitin proteasome system.
Autorzy:
Kandel R; School of Biological Sciences, Department of Cell and Developmental Biology, University of California San Diego, La Jolla, CA 92093, United States.
Jung J; School of Biological Sciences, Department of Cell and Developmental Biology, University of California San Diego, La Jolla, CA 92093, United States.
Neal S; School of Biological Sciences, Department of Cell and Developmental Biology, University of California San Diego, La Jolla, CA 92093, United States; Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address: .
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Źródło:
Seminars in cell & developmental biology [Semin Cell Dev Biol] 2024 Mar 15; Vol. 156, pp. 107-120. Date of Electronic Publication: 2023 Sep 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Ubiquitin*/metabolism
Proteasome Endopeptidase Complex*/metabolism
Animals ; Proteotoxic Stress ; Proteins/metabolism ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
Potential of the nanoplatform and PROTAC interface to achieve targeted protein degradation through the Ubiquitin-Proteasome system.
Autorzy:
Xie H; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, China.
Zhang C; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, China. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2024 Mar 05; Vol. 267, pp. 116168. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Proteasome Endopeptidase Complex*
Ubiquitin*
Proteolysis ; Cytoplasm ; Drug Delivery Systems ; Ubiquitin-Protein Ligases
Czasopismo naukowe
Tytuł:
Discovery of Kinetin in inhibiting colorectal cancer progression via enhancing PSMB1-mediated RAB34 degradation.
Autorzy:
Jiang X; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China.
Yang L; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China.
Chen G; Artificial Intelligence Medical Research Center, School of Intelligent Systems Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, 510275, China.
Feng X; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China; Department of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510655, China.
Liu Y; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China; Department of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510655, China.
Gao Q; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510655, China.
Mai M; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510655, China.
Chen CY; Department of AI for Science, School of Electronic and Computer Engineering, Peking University Shenzhen Graduate School, Shenzhen, Guangdong, 518055, China.
Ye S; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China; Department of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510655, China.
Yang Z; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China; Department of Clinical Laboratory, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510655, China. Electronic address: .
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Źródło:
Cancer letters [Cancer Lett] 2024 Mar 01; Vol. 584, pp. 216600. Date of Electronic Publication: 2023 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/metabolism
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/metabolism
Humans ; Kinetin ; Proteomics ; Mitogen-Activated Protein Kinase Kinases ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Nano-PROTACs: state of the art and perspectives.
Autorzy:
Zhong J; Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Ministry of Education of China, Beijing Laboratory of Biomedical Materials, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. .; Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, China. .
Zhao R; Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, China. .
Wang Y; Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Ministry of Education of China, Beijing Laboratory of Biomedical Materials, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. .
Su YX; Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR 999077, China. .
Lan X; Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Ministry of Education of China, Beijing Laboratory of Biomedical Materials, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. .
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Źródło:
Nanoscale [Nanoscale] 2024 Feb 29; Vol. 16 (9), pp. 4378-4391. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Proteolysis Targeting Chimera*
Proteasome Endopeptidase Complex*/metabolism
Proteolysis ; Proteins/metabolism ; Drug Discovery/methods
Czasopismo naukowe
Tytuł:
Interactions Between the Ubiquitin-Proteasome System, Nrf2, and the Cannabinoidome as Protective Strategies to Combat Neurodegeneration: Review on Experimental Evidence.
Autorzy:
Monsalvo-Maraver LA; Facultad de Ciencias, Universidad Nacional Autónoma de México, Av. Universidad 3000, C.U. Coyoacán, 04510, Mexico City, Mexico. .
Ovalle-Noguez EA; Facultad de Ciencias, Universidad Nacional Autónoma de México, Av. Universidad 3000, C.U. Coyoacán, 04510, Mexico City, Mexico.
Nava-Osorio J; Facultad de Ciencias, Universidad Nacional Autónoma de México, Av. Universidad 3000, C.U. Coyoacán, 04510, Mexico City, Mexico.
Maya-López M; Facultad de Ciencias, Universidad Nacional Autónoma de México, Av. Universidad 3000, C.U. Coyoacán, 04510, Mexico City, Mexico.; Doctorado en Ciencias Biológicas y de La Salud, Universidad Autónoma Metropolitana-Iztapalapa, Mexico City, Mexico.
Rangel-López E; Instituto Nacional de Neurología y Neurocirugía, S.S.A., Mexico City, Mexico.
Túnez I; Instituto de Investigaciones Biomédicas Maimonides de Córdoba (IMIBIC), Departamento de Bioquímica y Biología Molecular, Facultad de Medicina y Enfermería, Universidad de Córdoba, Red Española de Excelencia en Estimulación Cerebral (REDESTIM), Córdoba, Spain.
Tinkov AA; IM Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.; Yaroslavl State University, Yaroslavl, Russia.
Tizabi Y; Department of Pharmacology, Howard University College of Medicine, Washington, DC, USA.
Aschner M; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.
Santamaría A; Facultad de Ciencias, Universidad Nacional Autónoma de México, Av. Universidad 3000, C.U. Coyoacán, 04510, Mexico City, Mexico. .
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Corporate Authors:
Students from Programa Delfín 2022
Źródło:
Neurotoxicity research [Neurotox Res] 2024 Feb 23; Vol. 42 (2), pp. 18. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Proteasome Endopeptidase Complex*/metabolism
Neurodegenerative Diseases*/metabolism
Humans ; Ubiquitin/metabolism ; NF-E2-Related Factor 2/metabolism ; Cytoplasm/metabolism
Czasopismo naukowe
Tytuł:
Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing.
Autorzy:
Soh WT; Research Group of Quantitative and Systems Biology, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.
Roetschke HP; Research Group of Quantitative and Systems Biology, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.; Centre for Inflammation Biology and Cancer Immunology & Peter Gorer Department of Immunobiology, King's College London, SE1 1UL, London, UK.; Research Group of Molecular Immunology, Francis Crick Institute, NW1 1AT, London, UK.
Cormican JA; Research Group of Quantitative and Systems Biology, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.
Teo BF; Centre for Inflammation Biology and Cancer Immunology & Peter Gorer Department of Immunobiology, King's College London, SE1 1UL, London, UK.; Research Group of Molecular Immunology, Francis Crick Institute, NW1 1AT, London, UK.; Immunology Programme, Life Sciences Institute; Immunology Translational Research Program and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore.
Chiam NC; Research Group of Quantitative and Systems Biology, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.
Raabe M; Research Group of Bioanalytical Mass Spectrometry, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.
Pflanz R; Research Group of Bioanalytical Mass Spectrometry, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.
Henneberg F; Department of Structural Dynamics, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.
Becker S; Department of NMR-based Structural Biology, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.
Chari A; Research Group of Structural Biochemistry and Mechanisms, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.
Liu H; Immunology Programme, Life Sciences Institute; Immunology Translational Research Program and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore.
Urlaub H; Research Group of Bioanalytical Mass Spectrometry, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.; Institute of Clinical Chemistry, University Medical Center Göttingen, 37075, Göttingen, Germany.
Liepe J; Research Group of Quantitative and Systems Biology, Max-Planck-Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany. .
Mishto M; Centre for Inflammation Biology and Cancer Immunology & Peter Gorer Department of Immunobiology, King's College London, SE1 1UL, London, UK. .; Research Group of Molecular Immunology, Francis Crick Institute, NW1 1AT, London, UK. .
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Źródło:
Nature communications [Nat Commun] 2024 Feb 07; Vol. 15 (1), pp. 1147. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/metabolism
Peptides*/metabolism
Humans ; Proteolysis ; Hydrolysis ; Proteins/metabolism
Czasopismo naukowe
Tytuł:
Knockout of PA200 improves proteasomal degradation and myelination in a proteotoxic neuropathy.
Autorzy:
VerPlank JJ; https://ror.org/01y64my43 Department of Biochemistry, Institute for Myelin and Glia Exploration, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA .
Gawron JM; https://ror.org/01y64my43 Department of Biochemistry, Institute for Myelin and Glia Exploration, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.
Silvestri NJ; Department of Neurology, Institute for Myelin and Glia Exploration, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.
Wrabetz L; https://ror.org/01y64my43 Department of Biochemistry, Institute for Myelin and Glia Exploration, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.; Department of Neurology, Institute for Myelin and Glia Exploration, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.
Feltri ML; https://ror.org/01y64my43 Department of Biochemistry, Institute for Myelin and Glia Exploration, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.; Department of Neurology, Institute for Myelin and Glia Exploration, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.; IRCCS Neurological Institute 'Carlo Besta,' Milano, Italy.; Department of Medical Biotechnology and Translational Medicine, Universita' degli Studi di Milano, Milano, Italy.
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Źródło:
Life science alliance [Life Sci Alliance] 2024 Feb 06; Vol. 7 (4). Date of Electronic Publication: 2024 Feb 06 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/metabolism
Charcot-Marie-Tooth Disease*/genetics
Mice ; Animals ; Mice, Knockout ; Proteolysis ; Cytoplasm/metabolism
Czasopismo naukowe
Tytuł:
CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy.
Autorzy:
Tang P; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China; Tianjin Institutes of Health Science, Tianjin, China.
Yu Z; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China; Tianjin Institutes of Health Science, Tianjin, China.
Sun H; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
Liu L; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China; Tianjin Institutes of Health Science, Tianjin, China.
Gong L; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
Fang T; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
Sun X; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
Xie S; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
An G; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
Xu Z; Hematology Department Fujian Medical University Union Hospital, Fujian Institute of Hematology, Fuzhou, Fujian, China. Electronic address: .
Qiu L; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China; Tianjin Institutes of Health Science, Tianjin, China; Gobroad Healthcare Group, Beijing, China. Electronic address: .
Hao M; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China; Tianjin Institutes of Health Science, Tianjin, China. Electronic address: .
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Źródło:
EBioMedicine [EBioMedicine] 2024 Feb; Vol. 100, pp. 104961. Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/metabolism
Multiple Myeloma*/drug therapy
Humans ; Animals ; Mice ; Proteasome Inhibitors/pharmacology ; Ubiquitin-Specific Peptidase 7/metabolism ; Cell Line, Tumor ; Lysosomes/metabolism ; Autophagy/genetics ; Carrier Proteins/metabolism ; LIM Domain Proteins
Czasopismo naukowe
Tytuł:
Derailed protein turnover in the aging mammalian brain.
Autorzy:
Rao NR; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Upadhyay A; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Savas JN; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA. .
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Źródło:
Molecular systems biology [Mol Syst Biol] 2024 Feb; Vol. 20 (2), pp. 120-139. Date of Electronic Publication: 2024 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/metabolism
Proteome*/metabolism
Male ; Female ; Animals ; Mice ; Aging/metabolism ; Proteolysis ; Brain/metabolism ; Mammals ; Isotope Labeling
Czasopismo naukowe
Tytuł:
Discovery and Development of Cyclic Peptide Proteasome Stimulators.
Autorzy:
Nelson S; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, 47906, USA.
Harris TJ; Department of Pharmaceutical Sciences, University of California-Irvine, Irvine, California, 92697, USA.
Muli CS; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, 47906, USA.
Maresh ME; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, 47906, USA.
Baker B; Department of Chemistry, Purdue University, West Lafayette, Indiana, 47906, USA.
Smith C; Department of Chemistry, Purdue University, West Lafayette, Indiana, 47906, USA.
Neumann C; Department of Chemistry, Purdue University, West Lafayette, Indiana, 47906, USA.
Trader DJ; Department of Pharmaceutical Sciences, University of California-Irvine, Irvine, California, 92697, USA.
Parkinson EI; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, 47906, USA.; Department of Chemistry, Purdue University, West Lafayette, Indiana, 47906, USA.
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Źródło:
Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Feb 01; Vol. 25 (3), pp. e202300671. Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/metabolism
Neurodegenerative Diseases*/drug therapy
Humans ; Peptides, Cyclic/pharmacology ; Peptides, Cyclic/metabolism ; Proteolysis ; Proteins/metabolism
Czasopismo naukowe
Tytuł:
Lanosterol elevates cytoprotective response through induced-proteasomal degradation of aberrant proteins.
Autorzy:
Kinger S; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342037, India.
Jagtap YA; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342037, India.
Dubey AR; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342037, India.
Kumar P; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342037, India.
Choudhary A; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342037, India.
Dhiman R; Laboratory of Mycobacterial Immunology, Department of Life Science, National Institute of Technology, Rourkela 769008, India.
Prajapati VK; Department of Biochemistry, University of Delhi South Campus, Benito Juarez Road, Dhaula Kuan, New Delhi 110021, India.
Chitkara D; Department of Pharmacy, Birla Institute of Technology and Science, Pilani (BITS-Pilani), Vidya Vihar Campus, Pilani 333031, India.
Poluri KM; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India.
Mishra A; Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Rajasthan 342037, India. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2024 Feb; Vol. 1871 (2), pp. 119631. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proteasome Endopeptidase Complex*/metabolism
Protein Folding*
Lanosterol/pharmacology ; Proteins/metabolism ; Proteostasis
Czasopismo naukowe
Tytuł:
Frameshift variants in the C-terminal of CTNNB1 cause familial exudative vitreoretinopathy by AXIN1-mediated ubiquitin-proteasome degradation condensation.
Autorzy:
Liu Y; Central Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yang M; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics and Department of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China; Research Unit for Blindness Prevention, Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China; Jinfeng Laboratory, Chongqing, China.
Fan L; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, Sichuan, China; The University of Chinese Academy of Sciences, Beijing, China.
He Y; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics and Department of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China; Research Unit for Blindness Prevention, Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
Dai E; Department of Ophthalmology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liu M; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics and Department of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China; Research Unit for Blindness Prevention, Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
Jiang L; Central Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. Electronic address: .
Yang Z; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics and Department of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China; Research Unit for Blindness Prevention, Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China; Jinfeng Laboratory, Chongqing, China; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, Sichuan, China; The University of Chinese Academy of Sciences, Beijing, China. Electronic address: .
Li S; Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics and Department of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China; Research Unit for Blindness Prevention, Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China; Jinfeng Laboratory, Chongqing, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2024 Feb; Vol. 258 (Pt 1), pp. 128570. Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/genetics
Ubiquitin*/genetics
Humans ; Familial Exudative Vitreoretinopathies/genetics ; beta Catenin/metabolism ; Endothelial Cells/metabolism ; Mutation ; DNA Mutational Analysis ; Axin Protein/genetics
Czasopismo naukowe
Tytuł:
Recent advances in targeted protein degraders as potential therapeutic agents.
Autorzy:
Yang N; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, People's Republic of China.
Kong B; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, People's Republic of China.
Zhu Z; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, People's Republic of China.
Huang F; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, People's Republic of China.
Zhang L; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, People's Republic of China.
Lu T; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, People's Republic of China.; State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China.
Chen Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, People's Republic of China. .
Zhang Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, People's Republic of China. .
Jiang Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198, People's Republic of China. .
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Źródło:
Molecular diversity [Mol Divers] 2024 Feb; Vol. 28 (1), pp. 309-333. Date of Electronic Publication: 2023 Feb 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Proteasome Endopeptidase Complex*
Transcription Factors*
Dietary Supplements ; Drug Discovery ; Ubiquitins ; Proteolysis
Czasopismo naukowe
Tytuł:
Studying Antifatigue Mechanism of Tyr-Pro-Leu-Pro in Exercise Mice Using Label-Free Proteomics.
Autorzy:
Cai J; State Key Laboratory of Meat Quality Control and Cultured Meat Development, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China.
Tao Y; State Key Laboratory of Meat Quality Control and Cultured Meat Development, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China.
Xing L; State Key Laboratory of Meat Quality Control and Cultured Meat Development, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China.
Zhang J; State Key Laboratory of Meat Quality Control and Cultured Meat Development, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China.
Wang Z; State Key Laboratory of Meat Quality Control and Cultured Meat Development, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China.
Zhu Z; State Key Laboratory of Meat Quality Control and Cultured Meat Development, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China.
Zhang W; State Key Laboratory of Meat Quality Control and Cultured Meat Development, College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China.
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Źródło:
Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Jan 31; Vol. 72 (4), pp. 2178-2192. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/genetics
Proteomics*
Dipeptides*
Animals ; Mice ; Mice, Inbred ICR ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of mitochondrial cyclophilin D, a downstream target of glycogen synthase kinase 3α, improves sperm motility.
Autorzy:
Park SH; Department of Life Science and Institute for Natural Sciences, Hanyang University, Seoul, 04763, Republic of Korea.
Gye MC; Department of Life Science and Institute for Natural Sciences, Hanyang University, Seoul, 04763, Republic of Korea. .
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Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2024 Jan 22; Vol. 22 (1), pp. 15. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Glycogen Synthase Kinase 3*
Peptidyl-Prolyl Isomerase F*/antagonists & inhibitors
Peptidyl-Prolyl Isomerase F*/metabolism
Proteasome Endopeptidase Complex*
Sperm Motility*/genetics
Animals ; Male ; Mice ; Adenosine Triphosphate/pharmacology ; Cyclosporine/pharmacology ; Semen ; Ubiquitins
Czasopismo naukowe
Tytuł:
An E3 ubiquitin-proteasome gene signature for predicting prognosis in patients with pancreatic cancer.
Autorzy:
Yin T; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wen J; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xu S; Department of Endocrinology, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Chen L; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhang Z; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Pan S; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhou M; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Guo X; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wang M; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Gong J; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhang H; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Qin R; Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2024 Jan 18; Vol. 14, pp. 1332626. Date of Electronic Publication: 2024 Jan 18 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Proteasome Endopeptidase Complex*/genetics
Pancreatic Neoplasms*/diagnosis
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/therapy
Humans ; Prognosis ; Ubiquitin-Protein Ligases/genetics ; Ubiquitins
Czasopismo naukowe
Tytuł:
Targeted Protein Degradation Systems: Controlling Protein Stability Using E3 Ubiquitin Ligases in Eukaryotic Species.
Autorzy:
Ogawa Y; Department of Biological Science, Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan.
Ueda TP; Department of Biological Science, Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan.
Obara K; Department of Biological Science, Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan.
Nishimura K; Department of Biological Science, Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan.
Kamura T; Department of Biological Science, Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan.
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Źródło:
Cells [Cells] 2024 Jan 17; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Proteasome Endopeptidase Complex*
Ubiquitin-Protein Ligases*
Proteolysis ; Cytoplasm ; Protein Stability
Czasopismo naukowe

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