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Wyszukujesz frazę ""Protein Binding/drug effects"" wg kryterium: Temat


Tytuł :
Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking.
Autorzy :
Tinker, Andrew
Harmer, Stephen C.
Royal, Alice A.
Pokaż więcej
Temat :
Mutation/genetics
Cell Membranes
Lipids
Cell Physiology
Chemical Properties
Endoplasmic Reticulum/drug effects
Physical Sciences
Potassium Channels
Cricetulus
Animals
HEK293 Cells
Phosphatidylinositol 4,5-Diphosphate/metabolism
Biology and Life Sciences
Physical Chemistry
Neuroscience
lipids (amino acids, peptides, and proteins)
Sirolimus/pharmacology
Ion Channel Gating/drug effects
Physiology
Enzymology
Cell Membrane/drug effects
Electrophysiology
Biological Cultures
Science
Protein Multimerization/drug effects
Neurophysiology
Phosphatases
Research Article
Enzymes
Protein Transport/drug effects
Golgi Apparatus/drug effects
Proteins
Physics
CHO Cells
Biophysics
Membrane Trafficking
Chemistry
Potassium Channels, Voltage-Gated/metabolism
Research and Analysis Methods
Dimerization
Medicine
Ion Channels
KCNQ1 Potassium Channel/metabolism
Protein Binding/drug effects
Cricetinae
Genes, Reporter
Cell Biology
Cellular Structures and Organelles
Biochemistry
Journal Article
Cell Cultures
Medicine and Health Sciences
Humans
Źródło :
PLoS ONE, Vol 12, Iss 10, p e0186293 (2017)
Royal, A A, Tinker, A & Harmer, S C 2017, ' Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking ', PLoS ONE, vol. 12, no. 10, e0186293 . https://doi.org/10.1371/journal.pone.0186293
Opis pliku :
application/pdf
Tytuł :
Enhancer-mediated oncogenic function of the menin tumor suppressor in breast cancer
Autorzy :
Dreijerink, Koen M.A.
Groner, Anna C.
Voc, Erica S.M.
Font-Tello, Alba
Gu, Lei
Chi, David
Reyes, Jaime
Cook, Jennifer
Lim, Elgene
Lin, Charles Y.
De Laat, Wouter
Rao, Prakash K.
Long, Henry W.
Brown, Myles
Pokaż więcej
Temat :
endocrine system
enhancer
transcription
Breast Neoplasms
Estrogen Receptor alpha
tumor suppressor
Hepatocyte Nuclear Factor 3-alpha
Proto-Oncogene Proteins
epigenetics
endocrine system diseases
Histones
menin
Genomics
Transcription, Genetic
Female
Estradiol
Breast Neoplasms/genetics
Enhancer Elements, Genetic
congenital, hereditary, and neonatal diseases and abnormalities
Cell Proliferation
Estrogen Receptor alpha/metabolism
MEN1
Oncogenes
breast cancer
Lysine/metabolism
histone H3K4 trimethylation
oncogene
Protein Binding
GATA3 Transcription Factor
Article
QH301-705.5
Cell Line, Tumor
Protein Binding/drug effects
Lysine
Biochemistry, Genetics and Molecular Biology(all)
Methylation
Promoter Regions, Genetic
Gene Expression Regulation, Neoplastic
Proto-Oncogene Proteins/genetics
Estradiol/pharmacology
Enhancer Elements, Genetic/genetics
Hepatocyte Nuclear Factor 3-alpha/metabolism
Journal Article
GATA3 Transcription Factor/metabolism
Histones/metabolism
Tumor Suppressor
Humans
Biology (General)
Źródło :
Cell Reports, Vol 18, Iss 10, Pp 2359-2372 (2017)
Cell Reports [E], 18(10), 2359. Cell Press
Cell Reports, 18(10), 2359 - 2372. Cell Press
Opis pliku :
application/application/pdf; image/pdf
Tytuł :
The interaction between signal regulatory protein alpha (SIRPα) and CD47: structure, function, and therapeutic target
Autorzy :
Barclay, A Neil
Van den Berg, Timo K
Pokaż więcej
Temat :
Dendritic Cells/immunology
Signal Transduction
Antigens, Differentiation/chemistry
CD47 Antigen/chemistry
Hematologic Diseases/drug therapy
Receptors, Immunologic/chemistry
Protein Binding/drug effects
T-Lymphocytes/immunology
Autoimmune Diseases/drug therapy
Neoplasms/drug therapy
Phagocytosis/drug effects
Molecular Targeted Therapy
Animals
Humans
Immunological Synapses/immunology
Multigene Family
Źródło :
Annual review of immunology, 32, 25 - 50. Annual Reviews Inc.
Annual Review of Immunology, 32, 25 - 50. Annual Reviews Inc.
Tytuł :
The AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for viral replication.
Autorzy :
Colin, L
Vandenhoudt, N
de Walque, S
Van Driessche, B
Bergamaschi, Anna
Martinelli, V
Cherrier, Thomas
Vanhulle, C
Guiguen, A
David, Annie
Burny, A
Herbein, G
Pancino, Gianfranco
Rohr, Olivier
Van Lint, C
Pokaż więcej
Temat :
Sciences bio-médicales et agricoles
[SDV.BC]Life Sciences [q-bio]/Cellular Biology
Proto-Oncogene Proteins c-jun/metabolism
Macrophages -- drug effects -- virology
Virus Replication/genetics
DNA
Point Mutation -- genetics
Point Mutation/genetics
Transcription Factor AP-1 -- metabolism
Proto-Oncogene Proteins c-fos/metabolism
Tetradecanoylphorbol Acetate/pharmacology
Base Sequence
tat Gene Products, Human Immunodeficiency Virus
Binding Sites
Genes, pol -- genetics
Genes, pol/genetics
T-Lymphocytes/drug effects/virology
Biology
Virus Replication -- genetics
Nucleic acids
Enhancer Elements, Genetic -- genetics
Jurkat Cells
Proto-Oncogene Proteins c-fos -- metabolism
HIV-1/genetics/physiology
Viral Replication
Viral Replication Complex
Science
HIV-1 -- genetics -- physiology
Tetradecanoylphorbol Acetate -- pharmacology
Biochemistry, biophysics & molecular biology [Life sciences]
Regulatory Sequences, Nucleic Acid -- genetics
T-Lymphocytes -- drug effects -- virology
Research Article
Molecular Sequence Data
DNA replication
Genes, Dominant/genetics
Immunodeficiency Viruses
Proto-Oncogene Proteins c-jun -- metabolism
Monocytes/drug effects/virology
RNA Polymerase II -- metabolism
Biochimie, biophysique & biologie moléculaire [Sciences du vivant]
Microbiology
Medicine
Genes, Dominant -- genetics
Protein Binding/drug effects
Transcription Factor AP-1/metabolism
Regulatory Sequences, Nucleic Acid/genetics
Virology
Biochemistry
Enhancer Elements, Genetic/genetics
Protein Binding -- drug effects
RNA Polymerase II/metabolism
Viral Nucleic Acid
Humans
Monocytes -- drug effects -- virology
Macrophages/drug effects/virology
Źródło :
PLoS ONE, Public Library of Science, 2011, 6 (4), ⟨10.1371/journal.pone.0019084⟩
PLoS ONE, Vol 6, Iss 4, p e19084 (2011)
PLoS ONE, 6(4), 19084. United States (2011).
Opis pliku :
1 full-text file(s): application/pdf
Tytuł :
An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ.
Autorzy :
Adolfsson, Oskar
Pihlgren, Maria
Toni, Nicolas
Varisco, Yvan
Buccarello, Anna Lucia
Antoniello, Katia
Lohmann, Sophie
Piorkowska, Kasia
Gafner, Valerie
Atwal, Jasvinder K.
Maloney, Janice
Chen, Mark
Gogineni, Alvin
Weimer, Robby M.
Mortensen, Deborah L.
Friesenhahn, Michel
Ho, Carole
Paul, Robert
Pfeifer, Andrea
Muhs, Andreas
Watts, Ryan J.
Pokaż więcej
Temat :
Aged
Aged, 80 and over
Alzheimer Disease/blood
Alzheimer Disease/immunology
Amyloid beta-Peptides/immunology
Amyloid beta-Peptides/metabolism
Amyloid beta-Protein Precursor/genetics
Animals
Animals, Newborn
Cells, Cultured
Cerebral Cortex/cytology
Disease Models, Animal
Dose-Response Relationship, Drug
Dose-Response Relationship, Immunologic
Double-Blind Method
Enzyme-Linked Immunosorbent Assay
Female
Gene Expression Regulation/drug effects
Gene Expression Regulation/genetics
Green Fluorescent Proteins/genetics
Hippocampus/cytology
Humans
Immunoglobulin G/metabolism
Immunoglobulin G/pharmacology
Male
Mice
Mice, Transgenic
Microglia/drug effects
Microglia/metabolism
Microscopy, Confocal
Middle Aged
Mutation/genetics
Neurons/drug effects
Neurons/metabolism
Neuroprotective Agents/metabolism
Neuroprotective Agents/pharmacology
Peptide Fragments/metabolism
Plaque, Amyloid/immunology
Plaque, Amyloid/metabolism
Presenilin-1/genetics
Protein Binding/drug effects
Rats
Rats, Sprague-Dawley
Receptors, Chemokine/genetics
Statistics, Nonparametric
Time Factors
Tumor Necrosis Factor-alpha/metabolism
p38 Mitogen-Activated Protein Kinases/metabolism
Articles
Źródło :
Journal of Neuroscience, vol. 32, no. 28, pp. 9677-9689
Opis pliku :
application/pdf
Tytuł :
The TP53INP2 protein is required for autophagy in mammalian cells.
Autorzy :
Nowak, Jonathan
Archange, Cendrine
Tardivel-Lacombe, Joël
Pontarotti, Pierre
Pébusque, Marie-Josèphe
Vaccaro, Maria Inés
Velasco, Guillermo
Dagorn, Jean-Charles
Iovanna, Juan Lucio
Pokaż więcej
Temat :
MESH : Membrane Proteins: metabolism
MESH : Protein Transport: drug effects
MESH: Protein Binding: drug effects
MESH : Cloning, Molecular
MESH : Apoptosis Regulatory Proteins: metabolism
MESH : Animals
MESH : Carrier Proteins: chemistry,metabolism
MESH: Cloning, Molecular
MESH: Heat-Shock Proteins: chemistry,metabolism
MESH: Phagosomes: drug effects,metabolism
MESH : Sirolimus: pharmacology
MESH : Phagosomes: drug effects,metabolism
MESH : Gene Silencing: drug effects
MESH: Mice
MESH : Cell Line
MESH: Protein Transport: drug effects
MESH : Humans
MESH : Luminescent Measurements
MESH: Phylogeny
MESH: Nuclear Proteins: chemistry,metabolism
MESH: Conserved Sequence
MESH : Molecular Sequence Data
MESH: Molecular Sequence Data
MESH: Animals
MESH : Heat-Shock Proteins: chemistry,metabolism
MESH : Phylogeny
MESH: Apoptosis Regulatory Proteins: metabolism
MESH : Amino Acid Sequence
MESH: Gene Silencing: drug effects
MESH: Amino Acid Sequence
MESH : Conserved Sequence
MESH : Nuclear Proteins: chemistry,metabolism
MESH: Autophagy: drug effects
MESH : Protein Binding: drug effects
[ SDV.OT ] Life Sciences [q-bio]/Other [q-bio.OT]
MESH : Adaptor Proteins, Signal Transducing: metabolism
MESH: Cell Line
MESH: Sirolimus: pharmacology
MESH : Microtubule-Associated Proteins: metabolism
MESH: Carrier Proteins: chemistry,metabolism
MESH: Humans
MESH: Adaptor Proteins, Signal Transducing: metabolism
MESH: Microtubule-Associated Proteins: metabolism
[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT]
MESH: Membrane Proteins: metabolism
MESH: Luminescent Measurements
MESH : Autophagy: drug effects
Articles
MESH : Mice
Źródło :
Molecular Biology of the Cell, American Society for Cell Biology, 2009, 20 (3), pp.870-81. ⟨10.1091/mbc.E08-07-0671⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2009, 20 (3), pp.870-81. 〈10.1091/mbc.E08-07-0671〉
Molecular Biology of the Cell

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