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Wyszukujesz frazę ""Protein Biosynthesis"" wg kryterium: Temat


Tytuł :
TransCirc: an interactive database for translatable circular RNAs based on multi-omics evidence.
Autorzy :
Huang W; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.; University of Chinese Academy of Sciences, Beijing, China.
Ling Y; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.
Zhang S; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.; University of Chinese Academy of Sciences, Beijing, China.
Xia Q; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.; University of Chinese Academy of Sciences, Beijing, China.
Cao R; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.
Fan X; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.
Fang Z; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.; CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China.
Wang Z; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.; University of Chinese Academy of Sciences, Beijing, China.; CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China.
Zhang G; Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China.; University of Chinese Academy of Sciences, Beijing, China.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jan 08; Vol. 49 (D1), pp. D236-D242.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Databases, Nucleic Acid*
Protein Biosynthesis*
Software*
Adenosine/*analogs & derivatives
RNA, Circular/*genetics
Adenosine/metabolism ; Genomics/methods ; Humans ; Internal Ribosome Entry Sites ; Internet ; Machine Learning ; Molecular Sequence Annotation ; Open Reading Frames ; RNA, Circular/chemistry ; RNA, Circular/metabolism ; Ribosomes/genetics ; Ribosomes/metabolism
Czasopismo naukowe
Tytuł :
The coding capacity of SARS-CoV-2.
Autorzy :
Finkel Y; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Mizrahi O; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Nachshon A; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Weingarten-Gabbay S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismal and Evolutionary Biology, Harvard University, Cambridge, MA, USA.
Morgenstern D; de Botton Institute for Protein Profiling, The Nancy and Stephen Grand Israel National Center for Personalised Medicine, Weizmann Institute of Science, Rehovot, Israel.
Yahalom-Ronen Y; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Tamir H; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Achdout H; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Stein D; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona, Israel.
Israeli O; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona, Israel.
Beth-Din A; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona, Israel.
Melamed S; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Weiss S; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Israely T; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Paran N; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Schwartz M; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Stern-Ginossar N; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. .
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Źródło :
Nature [Nature] 2021 Jan; Vol. 589 (7840), pp. 125-130. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Protein Biosynthesis*
Genome, Viral/*genetics
Open Reading Frames/*genetics
SARS-CoV-2/*genetics
Viral Proteins/*biosynthesis
Viral Proteins/*genetics
Animals ; Cell Line ; Humans ; Molecular Sequence Annotation ; Peptides/genetics ; Peptides/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Ribosomes/metabolism ; SARS-CoV-2/immunology ; SARS-CoV-2/metabolism ; SARS-CoV-2/pathogenicity ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł :
Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.
Autorzy :
Yuan S; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
Peng L; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Systems Biology Institute, Yale University, West Haven, CT 06516, USA.
Park JJ; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Systems Biology Institute, Yale University, West Haven, CT 06516, USA.
Hu Y; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
Devarkar SC; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
Dong MB; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Systems Biology Institute, Yale University, West Haven, CT 06516, USA.
Shen Q; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
Wu S; Department of Pharmacology, Yale University, West Haven, CT 06516, USA.
Chen S; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Systems Biology Institute, Yale University, West Haven, CT 06516, USA. Electronic address: .
Lomakin IB; Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: .
Xiong Y; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Dec 17; Vol. 80 (6), pp. 1055-1066.e6. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Protein Biosynthesis*
COVID-19/*metabolism
RNA, Messenger/*metabolism
RNA, Viral/*metabolism
SARS-CoV-2/*metabolism
SARS-CoV-2/*pathogenicity
Viral Nonstructural Proteins/*metabolism
Animals ; COVID-19/genetics ; COVID-19/pathology ; Chlorocebus aethiops ; Cryoelectron Microscopy ; Humans ; RNA, Messenger/genetics ; RNA, Viral/genetics ; Ribosome Subunits, Small, Eukaryotic/genetics ; Ribosome Subunits, Small, Eukaryotic/metabolism ; Ribosome Subunits, Small, Eukaryotic/ultrastructure ; Ribosome Subunits, Small, Eukaryotic/virology ; SARS-CoV-2/genetics ; SARS-CoV-2/ultrastructure ; Vero Cells ; Viral Nonstructural Proteins/genetics
Czasopismo naukowe
Tytuł :
In silico mutagenesis of human ACE2 with S protein and translational efficiency explain SARS-CoV-2 infectivity in different species.
Autorzy :
Delgado Blanco J; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, Spain.
Hernandez-Alias X; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, Spain.
Cianferoni D; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, Spain.
Serrano L; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; ICREA, Pg. Lluís Companys 23, Barcelona, Spain.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2020 Dec 07; Vol. 16 (12), pp. e1008450. Date of Electronic Publication: 2020 Dec 07 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutagenesis*
Protein Biosynthesis*
Angiotensin-Converting Enzyme 2/*genetics
COVID-19/*genetics
COVID-19/*virology
Spike Glycoprotein, Coronavirus/*genetics
Alleles ; Animals ; Computer Simulation ; Crystallography, X-Ray ; Humans ; Immune System ; Protein Binding ; Protein Domains ; Protein Folding ; Protein Interaction Mapping ; Protein Structure, Secondary ; Proteome ; SARS-CoV-2 ; Species Specificity
Czasopismo naukowe
Tytuł :
RiboDiPA: a novel tool for differential pattern analysis in Ribo-seq data.
Autorzy :
Li K; Department of Statistics, Northwestern University, 633 Clark Street, Evanston, IL 60208, USA.; NSF-Simons Center for Quantitative Biology, Northwestern University, 633 Clark Street, Evanston, IL 60208, USA.
Hope CM; NSF-Simons Center for Quantitative Biology, Northwestern University, 633 Clark Street, Evanston, IL 60208, USA.; Department of Molecular Biosciences, Northwestern University, 633 Clark Street, Evanston, IL 60208, USA.
Wang XA; NSF-Simons Center for Quantitative Biology, Northwestern University, 633 Clark Street, Evanston, IL 60208, USA.; Department of Molecular Biosciences, Northwestern University, 633 Clark Street, Evanston, IL 60208, USA.
Wang JP; Department of Statistics, Northwestern University, 633 Clark Street, Evanston, IL 60208, USA.; NSF-Simons Center for Quantitative Biology, Northwestern University, 633 Clark Street, Evanston, IL 60208, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Dec 02; Vol. 48 (21), pp. 12016-12029.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Regulation, Fungal*
Protein Biosynthesis*
Software*
RNA, Fungal/*genetics
RNA, Messenger/*genetics
Ribosomes/*genetics
Saccharomyces cerevisiae/*genetics
Base Sequence ; Benchmarking ; Codon/chemistry ; Codon/metabolism ; High-Throughput Nucleotide Sequencing ; RNA, Fungal/metabolism ; RNA, Messenger/metabolism ; Ribosomes/metabolism ; Saccharomyces cerevisiae/metabolism ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
An RNA pseudoknot is essential for standby-mediated translation of the tisB toxin mRNA in Escherichia coli.
Autorzy :
Romilly C; Department of Cell and Molecular Biology, Uppsala University, Uppsala S-75124, Sweden.
Lippegaus A; Department of Cell and Molecular Biology, Uppsala University, Uppsala S-75124, Sweden.
Wagner EGH; Department of Cell and Molecular Biology, Uppsala University, Uppsala S-75124, Sweden.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Dec 02; Vol. 48 (21), pp. 12336-12347.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Bacterial*
Protein Biosynthesis*
Bacterial Toxins/*genetics
Escherichia coli/*genetics
Escherichia coli Proteins/*genetics
RNA, Bacterial/*genetics
RNA, Messenger/*genetics
Toxin-Antitoxin Systems/*genetics
Bacterial Toxins/metabolism ; Base Pairing ; Base Sequence ; Escherichia coli/metabolism ; Escherichia coli Proteins/metabolism ; Nucleic Acid Conformation ; Point Mutation ; Protein Binding ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; RNA, Bacterial/chemistry ; RNA, Bacterial/metabolism ; RNA, Messenger/chemistry ; RNA, Messenger/metabolism ; Ribosomal Proteins/genetics ; Ribosomal Proteins/metabolism ; Ribosome Subunits, Small, Bacterial/genetics ; Ribosome Subunits, Small, Bacterial/metabolism
Czasopismo naukowe
Tytuł :
SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses.
Autorzy :
Banerjee AK; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Blanco MR; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Bruce EA; Departments of Medicine, Division of Immunobiology and Microbiology, and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.
Honson DD; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Chen LM; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Chow A; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Bhat P; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Ollikainen N; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Quinodoz SA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Loney C; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
Thai J; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Miller ZD; Department of Surgery and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT 05405, USA.
Lin AE; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Schmidt MM; Departments of Medicine, Division of Immunobiology and Microbiology, and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.
Stewart DG; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
Goldfarb D; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
De Lorenzo G; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
Rihn SJ; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
Voorhees RM; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Botten JW; Departments of Medicine, Division of Immunobiology and Microbiology, and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.
Majumdar D; Department of Surgery and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: .
Guttman M; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: .
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Źródło :
Cell [Cell] 2020 Nov 25; Vol. 183 (5), pp. 1325-1339.e21. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Host-Pathogen Interactions*
Protein Biosynthesis*
RNA Splicing*
COVID-19/*metabolism
SARS-CoV-2/*metabolism
Viral Nonstructural Proteins/*metabolism
A549 Cells ; Animals ; COVID-19/virology ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Interferons/metabolism ; Protein Transport ; RNA, Messenger/metabolism ; RNA, Ribosomal, 18S/metabolism ; RNA, Small Cytoplasmic/chemistry ; RNA, Small Cytoplasmic/metabolism ; Signal Recognition Particle/chemistry ; Signal Recognition Particle/metabolism ; Vero Cells ; Viral Nonstructural Proteins/chemistry
Czasopismo naukowe
Tytuł :
Co-translational Insertion of Membrane Proteins into Preformed Nanodiscs.
Autorzy :
Levin R; Institute of Biophysical Chemistry, Goethe University Frankfurt.
Koeck Z; Institute of Biophysical Chemistry, Goethe University Frankfurt.
Dötsch V; Institute of Biophysical Chemistry, Goethe University Frankfurt.
Bernhard F; Institute of Biophysical Chemistry, Goethe University Frankfurt; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 Nov 19 (165). Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Protein Biosynthesis*
Membrane Proteins/*metabolism
Nanostructures/*chemistry
Cell-Free System/metabolism ; DNA-Directed RNA Polymerases/isolation & purification ; Green Fluorescent Proteins/metabolism ; Lipid Bilayers/chemistry ; Magnesium/pharmacology ; Rhodopsins, Microbial/metabolism ; Solubility ; Viral Proteins/isolation & purification
Czasopismo naukowe
Tytuł :
A translational program that suppresses metabolism to shield the genome.
Autorzy :
Balukoff NC; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.
Ho JJD; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.; Division of Hematology, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.
Theodoridis PR; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.
Wang M; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.
Bokros M; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.
Llanio LM; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.
Krieger JR; The SickKids Proteomics, Analytics, Robotics & Chemical Biology Centre (SPARC Biocentre), The Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada.; Bioinformatics Solutions Inc., Waterloo, ON, N2L 6J2, Canada.
Schatz JH; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.; Division of Hematology, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.
Lee S; Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA. .; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA. .; Department of Urology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 13; Vol. 11 (1), pp. 5755. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*
Protein Biosynthesis*
Peptide Initiation Factors/*metabolism
RNA-Binding Proteins/*metabolism
Acidosis/metabolism ; Acidosis/pathology ; Active Transport, Cell Nucleus ; Adenosine Triphosphate/metabolism ; Cell Hypoxia ; Cell Line, Tumor ; Cell Nucleus/metabolism ; Cell Proliferation ; Humans ; Mechanistic Target of Rapamycin Complex 1/antagonists & inhibitors ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Peptide Initiation Factors/genetics ; Proteomics ; RNA, Messenger/metabolism ; RNA-Binding Proteins/genetics ; Sirtuin 1/antagonists & inhibitors ; Sirtuin 1/metabolism ; Transcription, Genetic ; Tuberous Sclerosis Complex 2 Protein/genetics ; Tuberous Sclerosis Complex 2 Protein/metabolism
Czasopismo naukowe
Tytuł :
A phosphorylation-regulated eIF3d translation switch mediates cellular adaptation to metabolic stress.
Autorzy :
Lamper AM; Department of Biology, Brandeis University, Waltham, MA 02453, USA. .
Fleming RH; Department of Biology, Brandeis University, Waltham, MA 02453, USA.
Ladd KM; Department of Biology, Brandeis University, Waltham, MA 02453, USA.
Lee ASY; Department of Biology, Brandeis University, Waltham, MA 02453, USA. .
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Źródło :
Science (New York, N.Y.) [Science] 2020 Nov 13; Vol. 370 (6518), pp. 853-856.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Biosynthesis*
Stress, Physiological*
Eukaryotic Initiation Factor-3/*biosynthesis
Glucose/*deficiency
Adaptation, Physiological ; Cell Survival ; Eukaryotic Initiation Factor-3/genetics ; HEK293 Cells ; Humans ; Phosphorylation ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load.
Autorzy :
Kasetti RB; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, TX, 76107, Fort Worth, USA.
Patel PD; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, TX, 76107, Fort Worth, USA.
Maddineni P; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, TX, 76107, Fort Worth, USA.
Patil S; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, TX, 76107, Fort Worth, USA.
Kiehlbauch C; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, TX, 76107, Fort Worth, USA.
Millar JC; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, TX, 76107, Fort Worth, USA.
Searby CC; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.
Raghunathan V; Department of Basic Sciences and the Ocular Surface Institute, College of Optometry, University of Houston, Houston, TX, USA.; Department of Biomedical Engineering, Cullen College of Engineering, University of Houston, Houston, TX, USA.
Sheffield VC; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.
Zode GS; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, TX, 76107, Fort Worth, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 05; Vol. 11 (1), pp. 5594. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*/drug effects
Endoplasmic Reticulum Stress*/genetics
Protein Biosynthesis*/drug effects
Activating Transcription Factor 4/*metabolism
Glaucoma, Open-Angle/*metabolism
Activating Transcription Factor 4/antagonists & inhibitors ; Activating Transcription Factor 4/genetics ; Animals ; Aqueous Humor/metabolism ; Cell Death ; Cells, Cultured ; Glaucoma, Open-Angle/drug therapy ; Glaucoma, Open-Angle/pathology ; Humans ; Mice ; Ocular Hypertension/drug therapy ; Ocular Hypertension/metabolism ; Ocular Hypertension/pathology ; Optic Nerve/metabolism ; Optic Nerve/pathology ; Protein Phosphatase 1/genetics ; Protein Phosphatase 1/metabolism ; Retinal Ganglion Cells/metabolism ; Retinal Ganglion Cells/pathology ; Signal Transduction ; Trabecular Meshwork/drug effects ; Trabecular Meshwork/metabolism ; Trabecular Meshwork/pathology ; Transcription Factor CHOP/genetics ; Transcription Factor CHOP/metabolism
Czasopismo naukowe
Tytuł :
Cysteine oxidation and disulfide formation in the ribosomal exit tunnel.
Autorzy :
Schulte L; Institute of Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University of Frankfurt, Frankfurt, Germany.
Mao J; Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Frankfurt, Germany.
Reitz J; Institute for Biophysics, Buchmann Institute for Molecular Life Science, Goethe University Frankfurt, Frankfurt, Germany.
Sreeramulu S; Institute of Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University of Frankfurt, Frankfurt, Germany.
Kudlinzki D; Institute of Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University of Frankfurt, Frankfurt, Germany.
Hodirnau VV; Institute for Biophysics, Buchmann Institute for Molecular Life Science, Goethe University Frankfurt, Frankfurt, Germany.; Institute of Science and Technology Austria, Klosterneuburg, Austria.
Meier-Credo J; Max Planck Institute of Biophysics, Frankfurt, Germany.
Saxena K; Institute of Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University of Frankfurt, Frankfurt, Germany.
Buhr F; Institute of Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University of Frankfurt, Frankfurt, Germany.; Centre for Misfolding Diseases, University of Cambridge, Cambridge, UK.
Langer JD; Max Planck Institute of Biophysics, Frankfurt, Germany.
Blackledge M; Institute de Biologie Structurale, Grenoble, France. .
Frangakis AS; Institute for Biophysics, Buchmann Institute for Molecular Life Science, Goethe University Frankfurt, Frankfurt, Germany. .
Glaubitz C; Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Frankfurt, Germany. .
Schwalbe H; Institute of Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University of Frankfurt, Frankfurt, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 04; Vol. 11 (1), pp. 5569. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Biosynthesis*
Cysteine/*chemistry
Disulfides/*chemistry
Ribosomes/*chemistry
Ribosomes/*metabolism
gamma-Crystallins/*chemistry
Cryoelectron Microscopy ; Cysteine/metabolism ; Glutathione/analogs & derivatives ; Glutathione/chemistry ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Models, Molecular ; Mutation ; Oxidation-Reduction ; Protein Conformation ; Protein Folding ; Ribosomes/genetics ; S-Nitrosothiols/chemistry
Czasopismo naukowe
Tytuł :
Clingy genes: Why were genes for ribosomal proteins retained in many mitochondrial genomes?
Autorzy :
Bertgen L; Cell Biology, University of Kaiserslautern, Erwin-Schrödinger-Straße 13, 67663 Kaiserslautern, Germany.
Mühlhaus T; Computational Systems Biology, University of Kaiserslautern, Erwin-Schrödinger-Straße 23, 67663 Kaiserslautern, Germany.
Herrmann JM; Cell Biology, University of Kaiserslautern, Erwin-Schrödinger-Straße 13, 67663 Kaiserslautern, Germany. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Bioenergetics [Biochim Biophys Acta Bioenerg] 2020 Nov 01; Vol. 1861 (11), pp. 148275. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Genome, Mitochondrial*
Protein Biosynthesis*
Eukaryota/*metabolism
Mitochondrial Proteins/*metabolism
Ribosomal Proteins/*metabolism
Ribosomes/*metabolism
Eukaryota/genetics ; Mitochondrial Proteins/genetics ; Ribosomal Proteins/genetics ; Ribosomes/genetics
Czasopismo naukowe
Tytuł :
PsORF: a database of small ORFs in plants.
Autorzy :
Chen Y; College of Life Sciences, Wuhan University, Wuhan, China.
Li D; College of Life Sciences, Wuhan University, Wuhan, China.
Fan W; College of Life Sciences, Wuhan University, Wuhan, China.; State Key Laboratory of Virology, Wuhan University, Wuhan, China.
Zheng X; College of Life Sciences, Wuhan University, Wuhan, China.
Zhou Y; College of Life Sciences, Wuhan University, Wuhan, China.
Ye H; College of Life Sciences, Wuhan University, Wuhan, China.
Liang X; College of Life Sciences, Wuhan University, Wuhan, China.
Du W; College of Life Sciences, Wuhan University, Wuhan, China.
Zhou Y; College of Life Sciences, Wuhan University, Wuhan, China.; State Key Laboratory of Virology, Wuhan University, Wuhan, China.
Wang K; College of Life Sciences, Wuhan University, Wuhan, China.
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Źródło :
Plant biotechnology journal [Plant Biotechnol J] 2020 Nov; Vol. 18 (11), pp. 2158-2160. Date of Electronic Publication: 2020 May 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Plants*/genetics
Protein Biosynthesis*
Open Reading Frames
Czasopismo naukowe
Tytuł :
The protein translation machinery is expressed for maximal efficiency in Escherichia coli.
Autorzy :
Hu XP; Institute for Computer Science and Department of Biology, Heinrich Heine University, D-40225, Düsseldorf, Germany.
Dourado H; Institute for Computer Science and Department of Biology, Heinrich Heine University, D-40225, Düsseldorf, Germany.
Schubert P; Institute for Computer Science and Department of Biology, Heinrich Heine University, D-40225, Düsseldorf, Germany.
Lercher MJ; Institute for Computer Science and Department of Biology, Heinrich Heine University, D-40225, Düsseldorf, Germany. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 16; Vol. 11 (1), pp. 5260. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Biosynthesis*
Escherichia coli/*genetics
Escherichia coli Proteins/*genetics
Escherichia coli/metabolism ; Escherichia coli Proteins/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Transfer/genetics ; RNA, Transfer/metabolism ; Ribosomes/genetics ; Ribosomes/metabolism
Czasopismo naukowe
Tytuł :
Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
Autorzy :
Itoh Y; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, 17165, Solna, Sweden.; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 17165, Solna, Sweden.
Naschberger A; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, 17165, Solna, Sweden.
Mortezaei N; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, 17165, Solna, Sweden.
Herrmann JM; Cell Biology, University of Kaiserslautern, Erwin-Schrödinger-Straße 13, 67663, Kaiserslautern, Germany.
Amunts A; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, 17165, Solna, Sweden. .; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 17165, Solna, Sweden. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 14; Vol. 11 (1), pp. 5187. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Biosynthesis*
Mitochondria/*metabolism
Mitochondrial Ribosomes/*metabolism
Neurospora crassa/*physiology
Cell Fractionation ; Cryoelectron Microscopy ; Fungal Proteins/metabolism ; Mitochondria/ultrastructure ; Mitochondrial Proteins/metabolism ; Mitochondrial Ribosomes/ultrastructure ; Models, Molecular ; NAD/metabolism ; Proteins/metabolism ; RNA, Messenger/metabolism ; RNA, Ribosomal/metabolism ; RNA, Transfer/metabolism ; Ribosomal Proteins/metabolism
Czasopismo naukowe
Tytuł :
Association of host protein VARICOSE with HCPro within a multiprotein complex is crucial for RNA silencing suppression, translation, encapsidation and systemic spread of potato virus A infection.
Autorzy :
De S; University of Helsinki, Department of Microbiology and Viikki Plant Science Centre, Finland.
Pollari M; University of Helsinki, Department of Microbiology and Viikki Plant Science Centre, Finland.
Varjosalo M; Institute of Biotechnology, University of Helsinki, Finland.
Mäkinen K; University of Helsinki, Department of Microbiology and Viikki Plant Science Centre, Finland.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Oct 12; Vol. 16 (10), pp. e1008956. Date of Electronic Publication: 2020 Oct 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Encapsulation*
Protein Biosynthesis*
RNA Interference*
Plant Diseases/*virology
Plant Proteins/*metabolism
Potyvirus/*physiology
Tobacco/*virology
Viral Proteins/*metabolism
Multiprotein Complexes/genetics ; Multiprotein Complexes/metabolism ; Plant Proteins/genetics ; Tobacco/genetics ; Tobacco/metabolism ; Viral Proteins/genetics
SCR Organism :
Potato virus A
Czasopismo naukowe
Tytuł :
Comprehensive analysis of translation from overexpressed circular RNAs reveals pervasive translation from linear transcripts.
Autorzy :
Ho-Xuan H; Regensburg Center for Biochemistry (RCB), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.
Glažar P; Laboratory for Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max-Delbrück Center for Molecular Medicine, Berlin, Germany.
Latini C; Regensburg Center for Biochemistry (RCB), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.
Heizler K; Regensburg Center for Biochemistry (RCB), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.
Haase J; Institute of Molecular Medicine, Section for Molecular Cell Biology, Martin-Luther-University Halle-Wittenberg, Charles Tanford Protein Center, 06120 Halle, Germany.
Hett R; Regensburg Center for Biochemistry (RCB), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.
Anders M; Department of Surgery, University Hospital Regensburg, Regensburg, Germany.
Weichmann F; Regensburg Center for Biochemistry (RCB), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.
Bruckmann A; Regensburg Center for Biochemistry (RCB), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.
Van den Berg D; Department of Cell Biology, Erasmus MC, Wytemaweg 80, 3015 CN, Rotterdam, Netherlands.
Hüttelmaier S; Institute of Molecular Medicine, Section for Molecular Cell Biology, Martin-Luther-University Halle-Wittenberg, Charles Tanford Protein Center, 06120 Halle, Germany.
Rajewsky N; Laboratory for Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max-Delbrück Center for Molecular Medicine, Berlin, Germany.
Hackl C; Department of Surgery, University Hospital Regensburg, Regensburg, Germany.
Meister G; Regensburg Center for Biochemistry (RCB), Laboratory for RNA Biology, University of Regensburg, Regensburg, Germany.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Oct 09; Vol. 48 (18), pp. 10368-10382.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Biosynthesis*
Internal Ribosome Entry Sites/*genetics
Methyltransferases/*genetics
RNA, Circular/*genetics
Base Sequence/genetics ; Gene Expression Regulation/genetics ; HEK293 Cells ; Humans ; MicroRNAs/genetics ; RNA Splice Sites/genetics ; RNA, Circular/classification ; RNA-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy.
Autorzy :
Lauria F; Institute of Biophysics, CNR Unit at Trento, Trento, Italy.
Bernabò P; Institute of Biophysics, CNR Unit at Trento, Trento, Italy.
Tebaldi T; Department CIBIO, University of Trento, Trento, Italy.; Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
Groen EJN; Edinburgh Medical School, Biomedical Sciences & Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, UK.; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, Utrecht, the Netherlands.
Perenthaler E; Institute of Biophysics, CNR Unit at Trento, Trento, Italy.; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.
Maniscalco F; Institute of Biophysics, CNR Unit at Trento, Trento, Italy.; Department CIBIO, University of Trento, Trento, Italy.
Rossi A; Department CIBIO, University of Trento, Trento, Italy.
Donzel D; Institute of Biophysics, CNR Unit at Trento, Trento, Italy.
Clamer M; IMMAGINA Biotechnology s.r.l., Trento, Italy.
Marchioretto M; Institute of Biophysics, CNR Unit at Trento, Trento, Italy.
Omersa N; National Institute of Chemistry, Ljubljana, Slovenia.
Orri J; Institute of Biophysics, CNR Unit at Trento, Trento, Italy.; La Fundació Jesuïtes Educació, Barcelona, Spain.
Dalla Serra M; Institute of Biophysics, CNR Unit at Trento, Trento, Italy.
Anderluh G; National Institute of Chemistry, Ljubljana, Slovenia.
Quattrone A; Department CIBIO, University of Trento, Trento, Italy.
Inga A; Department CIBIO, University of Trento, Trento, Italy.
Gillingwater TH; Edinburgh Medical School, Biomedical Sciences & Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, UK.
Viero G; Institute of Biophysics, CNR Unit at Trento, Trento, Italy. .
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Źródło :
Nature cell biology [Nat Cell Biol] 2020 Oct; Vol. 22 (10), pp. 1239-1251. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Biosynthesis*
Motor Neurons/*pathology
Muscular Atrophy, Spinal/*pathology
Proteome/*analysis
RNA, Messenger/*metabolism
Ribosomes/*metabolism
Survival of Motor Neuron 1 Protein/*metabolism
Animals ; Disease Models, Animal ; Gene Expression Regulation ; Mice ; Motor Neurons/metabolism ; Muscular Atrophy, Spinal/genetics ; Muscular Atrophy, Spinal/metabolism ; RNA, Messenger/genetics ; Ribosomes/genetics ; Survival of Motor Neuron 1 Protein/genetics ; Transcriptome
Czasopismo naukowe
Tytuł :
Large-scale tethered function assays identify factors that regulate mRNA stability and translation.
Autorzy :
Luo EC; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Nathanson JL; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Tan FE; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Schwartz JL; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Schmok JC; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Shankar A; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Markmiller S; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Yee BA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Sathe S; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Pratt GA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Scaletta DB; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Ha Y; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Hill DE; Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Aigner S; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.
Yeo GW; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA. .; Stem Cell Program, University of California, San Diego, La Jolla, CA, USA. .; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA. .
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2020 Oct; Vol. 27 (10), pp. 989-1000. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Protein Biosynthesis*
RNA Stability*
Carrier Proteins/*metabolism
RNA-Binding Proteins/*metabolism
3' Untranslated Regions ; Binding Sites ; CRISPR-Cas Systems ; Carrier Proteins/chemistry ; Carrier Proteins/genetics ; Cell Line ; Humans ; Luciferases/genetics ; Luciferases/metabolism ; Open Reading Frames ; Polyribosomes/genetics ; Polyribosomes/metabolism ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/genetics ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Ultraviolet Rays
Czasopismo naukowe

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