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Wyszukujesz frazę ""Protein Carbamylation"" wg kryterium: Temat


Tytuł :
Impact of albumin carbamylation on immunoturbidimetric measurement of urinary albumin.
Autorzy :
Etchepare Cassol JP; Laboratory of Clinical Biochemistry, Department of Clinical and Toxicological Analysis, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Scolari R; Laboratory of Clinical Biochemistry, Department of Clinical and Toxicological Analysis, Federal University of Santa Maria, Santa Maria, RS, Brazil; University Hospital, Santa Maria, RS, Brazil.
Moresco RN; Laboratory of Clinical Biochemistry, Department of Clinical and Toxicological Analysis, Federal University of Santa Maria, Santa Maria, RS, Brazil. Electronic address: .
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Źródło :
Analytical biochemistry [Anal Biochem] 2021 Feb 01; Vol. 614, pp. 114047. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Carbamylation*
Albumins/*metabolism
Albuminuria/*diagnosis
Immunoturbidimetry/*methods
Humans ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/urine
Czasopismo naukowe
Tytuł :
Carbamylation of human serum albumin generates high-molecular weight aggregates: fine characterization by multi-spectroscopic methods and electron microscopy.
Autorzy :
Badar A; Department of Biochemistry, Faculty of Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Arif Z; Department of Biochemistry, Faculty of Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Qais FA; Department of Agricultural Microbiology, Faculty of Agricultural Sciences, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Islam SN; Department of Biochemistry, Faculty of Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Alam K; Department of Biochemistry, Faculty of Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 01; Vol. 164, pp. 2380-2388. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Aggregates*
Protein Carbamylation*
Amyloid/*chemistry
Serum Albumin, Human/*chemistry
Amyloid/ultrastructure ; Cyanates ; Humans ; Microscopy, Electron ; Spectrum Analysis
Czasopismo naukowe
Tytuł :
Activated neutrophil carbamylates albumin via the release of myeloperoxidase and reactive oxygen species regardless of NETosis.
Autorzy :
Nakabo S; Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.
Ohmura K; Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Akizuki S; Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Murakami K; Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nakashima R; Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hashimoto M; Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yoshifuji H; Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tanaka M; Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Mimori T; Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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Źródło :
Modern rheumatology [Mod Rheumatol] 2020 Mar; Vol. 30 (2), pp. 345-349. Date of Electronic Publication: 2019 May 02.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Carbamylation*
Albumins/*metabolism
Arthritis, Rheumatoid/*metabolism
Extracellular Traps/*metabolism
Peroxidase/*metabolism
Reactive Oxygen Species/*metabolism
Cells, Cultured ; Humans ; Neutrophils/metabolism
Czasopismo naukowe
Tytuł :
Carbamoylated Nail Proteins as Assessed by Near-Infrared Analysis are Associated with Load of Uremic Toxins and Mortality in Hemodialysis Patients.
Autorzy :
Bruyne S; Department of Clinical Chemistry, Ghent University, Ghent 9000, Belgium.
Himpe J; Department of Clinical Chemistry, Ghent University, Ghent 9000, Belgium.
Delanghe SE; Department of Nephrology, Ghent University, Ghent 9000, Belgium.
Glorieux G; Department of Nephrology, Ghent University, Ghent 9000, Belgium.
Biesen WV; Department of Nephrology, Ghent University, Ghent 9000, Belgium.
Buyzere ML; Department of Cardiology, Heart Center, Ghent University Hospital, Ghent 9000, Belgium.
Speeckaert MM; Department of Nephrology, Ghent University, Ghent 9000, Belgium.; Research Foundation Flanders, Brussels 1000, Belgium.
Delanghe JR; Department of Clinical Chemistry, Ghent University, Ghent 9000, Belgium.
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Źródło :
Toxins [Toxins (Basel)] 2020 Jan 26; Vol. 12 (2). Date of Electronic Publication: 2020 Jan 26.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Carbamylation*
Renal Dialysis*
Renal Insufficiency, Chronic*/blood
Renal Insufficiency, Chronic*/metabolism
Renal Insufficiency, Chronic*/mortality
Renal Insufficiency, Chronic*/therapy
Nails/*chemistry
Toxins, Biological/*blood
Adult ; Aged ; Female ; Humans ; Male ; Proportional Hazards Models ; Proteins/metabolism ; Spectroscopy, Near-Infrared ; Uremia
Czasopismo naukowe
Tytuł :
Carbamoylated erythropoietin produces antidepressant-like effects in male and female mice.
Autorzy :
Sampath D; Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, United States of America; Sioux Falls VA Healthcare System, Sioux Falls, SD 57105, United States of America. Electronic address: .
McWhirt J; Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, United States of America. Electronic address: .
Sathyanesan M; Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, United States of America; Sioux Falls VA Healthcare System, Sioux Falls, SD 57105, United States of America. Electronic address: .
Newton SS; Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, United States of America; Sioux Falls VA Healthcare System, Sioux Falls, SD 57105, United States of America. Electronic address: .
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Źródło :
Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2020 Jan 10; Vol. 96, pp. 109754. Date of Electronic Publication: 2019 Aug 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Carbamylation*
Antidepressive Agents/*therapeutic use
Depression/*drug therapy
Depression/*psychology
Erythropoietin/*therapeutic use
Animals ; Antidepressive Agents/chemical synthesis ; Erythropoietin/chemical synthesis ; Female ; Hindlimb Suspension/psychology ; Male ; Mice ; Mice, Inbred BALB C ; Sex Factors ; Swimming/psychology
Czasopismo naukowe
Tytuł :
Structure, catalytic mechanism, posttranslational lysine carbamylation, and inhibition of dihydropyrimidinases.
Autorzy :
Huang CY; School of Biomedical Sciences, Chung Shan Medical University, Taichung City, Taiwan; Department of Medical Research, Chung Shan Medical University Hospital, Taichung City, Taiwan.
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Źródło :
Advances in protein chemistry and structural biology [Adv Protein Chem Struct Biol] 2020; Vol. 122, pp. 63-96. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Carbamylation*
Amidohydrolases/*chemistry
Lysine/*chemistry
Amidohydrolases/metabolism ; Lysine/metabolism ; Nerve Tissue Proteins/chemistry ; Nerve Tissue Proteins/metabolism ; Structural Homology, Protein ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance.
Autorzy :
Yadav SPS; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
Sandoval RM; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
Zhao J; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas.
Huang Y; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas.
Wang E; Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, Texas.
Kumar S; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
Campos-Bilderback SB; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
Rhodes G; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
Mechref Y; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas.
Molitoris BA; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana.
Wagner MC; Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2021 Jan 01; Vol. 320 (1), pp. F114-F129. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Histocompatibility Antigens Class I/*metabolism
Kidney Tubules, Proximal/*metabolism
Liver/*metabolism
Receptors, Fc/*metabolism
Renal Insufficiency, Chronic/*metabolism
Serum Albumin/*metabolism
Animals ; Chromatography, Liquid ; Disease Models, Animal ; Glomerular Filtration Rate ; Kidney Tubules, Proximal/physiopathology ; Lysine ; Male ; Microscopy, Fluorescence, Multiphoton ; Protein Binding ; Protein Carbamylation ; Rats, Inbred Strains ; Rats, Sprague-Dawley ; Receptors, Cell Surface/metabolism ; Renal Insufficiency, Chronic/pathology ; Renal Insufficiency, Chronic/physiopathology ; Scattering, Small Angle ; Tandem Mass Spectrometry ; Time Factors ; X-Ray Diffraction
Czasopismo naukowe
Tytuł :
The Role of Nonenzymatic Post-translational Protein Modifications in Uremic Vascular Calcification.
Autorzy :
Lim K; Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Kalim S; Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA. Electronic address: .
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Źródło :
Advances in chronic kidney disease [Adv Chronic Kidney Dis] 2019 Nov; Vol. 26 (6), pp. 427-436.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Protein Carbamylation*
Protein Processing, Post-Translational*
Cardiovascular Diseases/*metabolism
Glycation End Products, Advanced/*metabolism
Kidney Failure, Chronic/*metabolism
Vascular Calcification/*metabolism
Animals ; Arteries ; Humans ; Kidney Failure, Chronic/complications ; Receptor for Advanced Glycation End Products/metabolism ; Uremia/complications ; Uremia/metabolism ; Vascular Calcification/etiology
Czasopismo naukowe
Tytuł :
High urea induces depression and LTP impairment through mTOR signalling suppression caused by carbamylation.
Autorzy :
Wang H; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China; Department of Anatomy, and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, China.
Huang B; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Wang W; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Li J; Department of Neurology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chen Y; Department of Anatomy, and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, China.
Flynn T; Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Zhao M; Department of Neurology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhou Z; Department of Radiology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Lin X; School of Public Health and Management, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Chongqing Medical University, Chongqing, China.
Zhang Y; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China; National Institute on Drug Dependence, Peking University, Bejing, China.
Xu M; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Li K; Chongqing Cancer Research Institute, Chongqing, China.
Tian K; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Yuan D; Department of Neurology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhou P; Department of Anatomy, and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, China.
Hu L; Department of Anatomy, and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, China.
Zhong D; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Zhu S; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Li J; Department of Anatomy, and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, China.
Chen D; Department of Anatomy, and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, China; Chongqing Three Gorges Medical College, Chongqing, China.
Wang K; Department of Anatomy, and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, China.
Liang J; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China; National Institute on Drug Dependence, Peking University, Bejing, China.
He Q; Center of Medical and Health Analysis, Peking University, Beijing, China.
Sun J; Clinical Laboratory, Peking University Third Hospital, Beijing, China.
Shi J; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China; National Institute on Drug Dependence, Peking University, Bejing, China.
Yan L; Ion Channel Explorer Bioscience INC., Beijing, China.
Sands JM; Renal Division, Department of Medicine and Department of Physiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Xie Z; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Lian X; School of Public Health and Management, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Chongqing Medical University, Chongqing, China.
Xu D; Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Ran J; Department of Anatomy, and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, China. Electronic address: .
Yang B; Department of Pharmacology, School of Basic Medical Sciences, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China. Electronic address: .
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Źródło :
EBioMedicine [EBioMedicine] 2019 Oct; Vol. 48, pp. 478-490. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Long-Term Potentiation*
Protein Carbamylation*
Signal Transduction*
Depression/*etiology
Depression/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Urea/*blood
Adult ; Aged ; Animals ; Brain/diagnostic imaging ; Brain/metabolism ; Brain/physiopathology ; Depression/diagnosis ; Disease Models, Animal ; Female ; Humans ; Male ; Mice ; Mice, Transgenic ; Middle Aged ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism
Czasopismo naukowe
Tytuł :
Diagnostic and prognostic value of anti-CarP antibodies in a sample of Egyptian rheumatoid arthritis patients.
Autorzy :
Elsayed SA; Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University, Sohag, Egypt. .
Esmail MA; Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University, Sohag, Egypt.
Ali RM; Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University, Sohag, Egypt.
Mohafez OM; Department of Biochemistry, Faculty of Pharmacy, Assiut Branch Al-Azhar University, Asyut, Egypt.
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Źródło :
Clinical rheumatology [Clin Rheumatol] 2019 Oct; Vol. 38 (10), pp. 2683-2689. Date of Electronic Publication: 2019 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Carbamylation*
Arthritis, Rheumatoid/*blood
Arthritis, Rheumatoid/*diagnosis
Arthritis, Rheumatoid/*immunology
Autoantibodies/*blood
Adult ; Alleles ; Autoantibodies/chemistry ; Biomarkers/blood ; Case-Control Studies ; Egypt ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Rheumatoid Factor/blood ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Could ornithine supplementation be beneficial to prevent the formation of pro-atherogenic carbamylated low-density lipoprotein (c-LDL) particles?
Autorzy :
Simsek B; Cerrahpasa Faculty of Medicine, Medical Program, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Çakatay U; Cerrahpasa Faculty of Medicine, Department of Medical Biochemistry, Istanbul University-Cerrahpasa, Istanbul, Turkey. Electronic address: .
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Źródło :
Medical hypotheses [Med Hypotheses] 2019 May; Vol. 126, pp. 20-22. Date of Electronic Publication: 2019 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Carbamylation*
Amino Acids/*metabolism
Atherosclerosis/*metabolism
Atherosclerosis/*therapy
Lipoproteins, LDL/*metabolism
Ornithine/*therapeutic use
Apolipoprotein B-100/chemistry ; Apolipoproteins/chemistry ; Atherosclerosis/physiopathology ; Humans ; Lysine/chemistry ; Models, Biological ; Ornithine/chemistry
Czasopismo naukowe
Tytuł :
Anti-carbamylated protein antibodies and skin involvement in patients with systemic sclerosis: An intriguing association.
Autorzy :
Favoino E; Department of Biomedical Sciences and Human Oncology (DIMO), Rheumatologic and Systemic Autoimmune Diseases Unit, University of Bari Medical School, Bari, Italy.
Prete M; Department of Biomedical Sciences and Human Oncology (DIMO), Rheumatologic and Systemic Autoimmune Diseases Unit, University of Bari Medical School, Bari, Italy.
Vettori S; Department of Clinical and Experimental Internal Medicine 'F. Magrassi-A. Lanzara', Rheumatology Section, University of Campania, Naples, Italy.
Corrado A; Department of Medical and Surgery Sciences, Rheumatology Unit, University of Foggia, Foggia, Italy.
Cantatore FP; Department of Medical and Surgery Sciences, Rheumatology Unit, University of Foggia, Foggia, Italy.
Valentini G; Department of Clinical and Experimental Internal Medicine 'F. Magrassi-A. Lanzara', Rheumatology Section, University of Campania, Naples, Italy.
Perosa F; Department of Biomedical Sciences and Human Oncology (DIMO), Rheumatologic and Systemic Autoimmune Diseases Unit, University of Bari Medical School, Bari, Italy.
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Źródło :
PloS one [PLoS One] 2018 Dec 31; Vol. 13 (12), pp. e0210023. Date of Electronic Publication: 2018 Dec 31 (Print Publication: 2018).
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Carbamylation*
Autoantibodies/*blood
Scleroderma, Systemic/*blood
Skin/*metabolism
Adult ; Animals ; Cattle ; Female ; Fibrinogen/metabolism ; Humans ; Male ; Middle Aged ; Scleroderma, Systemic/pathology ; Skin/pathology
Czasopismo naukowe
Tytuł :
Carbamylation promotes amyloidogenesis and induces structural changes in Tau-core hexapeptide fibrils.
Autorzy :
Guru KrishnaKumar V; Department of Biological Engineering, Indian Institute of Technology Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India.
Baweja L; Department of Biological Engineering, Indian Institute of Technology Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India; Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.
Ralhan K; Department of Biological Engineering, Indian Institute of Technology Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India.
Gupta S; Department of Biological Engineering, Indian Institute of Technology Gandhinagar, Palaj, Gandhinagar, Gujarat 382355, India. Electronic address: .
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2018 Dec; Vol. 1862 (12), pp. 2590-2604. Date of Electronic Publication: 2018 Jul 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Carbamylation*
Amyloid/*biosynthesis
Carrier Proteins/*chemistry
Oligopeptides/*chemistry
tau Proteins/*chemistry
Acetylation ; Alzheimer Disease/metabolism ; Amino Acid Sequence ; Amyloid/chemistry ; Humans ; Hydrogen Bonding ; Microscopy, Electron, Transmission ; Microscopy, Fluorescence ; Molecular Dynamics Simulation ; Peptides/chemistry ; Protein Conformation
Czasopismo naukowe
Tytuł :
Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site.
Autorzy :
Cheng JH; School of Biomedical Sciences, Chung Shan Medical University, No.110, Sec.1, Chien-Kuo N. Rd., Taichung City, Taiwan.
Huang YH; School of Biomedical Sciences, Chung Shan Medical University, No.110, Sec.1, Chien-Kuo N. Rd., Taichung City, Taiwan.
Lin JJ; School of Biomedical Sciences, Chung Shan Medical University, No.110, Sec.1, Chien-Kuo N. Rd., Taichung City, Taiwan; School of Medicine, College of Medicine, Chung Shan Medical University, No. 110, Sec. 1, Chien-Kuo N. Rd., Taichung City, Taiwan.
Huang CY; School of Biomedical Sciences, Chung Shan Medical University, No.110, Sec.1, Chien-Kuo N. Rd., Taichung City, Taiwan; Department of Medical Research, Chung Shan Medical University Hospital, No.110, Sec.1, Chien-Kuo N. Rd., Taichung City, Taiwan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 Oct 28; Vol. 505 (2), pp. 439-444. Date of Electronic Publication: 2018 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Carbamylation*
Amidohydrolases/*chemistry
Dihydroorotase/*chemistry
Lysine/*metabolism
Bacterial Proteins/chemistry ; Catalytic Domain ; Crystallography, X-Ray ; Humans ; Mass Spectrometry ; Mutant Proteins/chemistry ; Protein Binding ; Protein Processing, Post-Translational ; Pseudomonas aeruginosa/enzymology ; Zinc/metabolism
Czasopismo naukowe
Tytuł :
Decarbamoylation of acetylcholinesterases is markedly slowed as carbamoyl groups increase in size.
Autorzy :
Venkatasubban KS; University of North Florida, Department of Chemistry, Jacksonville, FL, 32224, USA.
Johnson JL; Mayo Clinic College of Medicine, Departments of Neuroscience and Pharmacology, Jacksonville, FL, 32224, USA.
Thomas JL; Mayo Clinic College of Medicine, Departments of Neuroscience and Pharmacology, Jacksonville, FL, 32224, USA.
Fauq A; Mayo Clinic College of Medicine, Departments of Neuroscience and Pharmacology, Jacksonville, FL, 32224, USA.
Cusack B; Mayo Clinic College of Medicine, Departments of Neuroscience and Pharmacology, Jacksonville, FL, 32224, USA.
Rosenberry TL; Mayo Clinic College of Medicine, Departments of Neuroscience and Pharmacology, Jacksonville, FL, 32224, USA. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2018 Oct 01; Vol. 655, pp. 67-74. Date of Electronic Publication: 2018 Aug 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Protein Carbamylation*
Acetylcholinesterase/*chemistry
Carbamates/*chemistry
Animals ; Catalytic Domain ; Cell Line ; Drosophila ; Enzyme Assays ; Humans ; Kinetics
Czasopismo naukowe
Tytuł :
Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product cis -2-butene-1,4-dial on human and rat hepatocytes.
Autorzy :
Teodoro JS; Department of Life Sciences of Faculty of Sciences and Technology, of the University of Coimbra, Coimbra, Portugal.; Center for Neurosciences and Cell Biology, of the University of Coimbra, Coimbra, Portugal.
Silva R; Center for Neurosciences and Cell Biology, of the University of Coimbra, Coimbra, Portugal.
Aguiar A; Chemistry Department, FCTUC, University of Coimbra, Coimbra, Portugal.
Sobral AJFN; Chemistry Department, FCTUC, University of Coimbra, Coimbra, Portugal.
Rolo AP; Department of Life Sciences of Faculty of Sciences and Technology, of the University of Coimbra, Coimbra, Portugal.; Center for Neurosciences and Cell Biology, of the University of Coimbra, Coimbra, Portugal.
Palmeira CM; Department of Life Sciences of Faculty of Sciences and Technology, of the University of Coimbra, Coimbra, Portugal.; Center for Neurosciences and Cell Biology, of the University of Coimbra, Coimbra, Portugal.
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Źródło :
Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Sep; Vol. 30 (7), pp. 536-545. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Aldehydes/*toxicity
Coffee/*toxicity
Furans/*toxicity
Hepatocytes/*drug effects
Seeds/*toxicity
8-Hydroxy-2'-Deoxyguanosine/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Cell Survival/drug effects ; Cells, Cultured ; Cooking ; DNA Damage ; Dose-Response Relationship, Drug ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Hot Temperature ; Humans ; Oxidative Stress/drug effects ; Protein Carbamylation/drug effects ; Rats ; Species Specificity ; Time Factors
Czasopismo naukowe
Tytuł :
[Protein carbamylation: what it is and why it concerns nephrologists].
Autorzy :
De Simone E; UOC Nefrologia, Ospedale Moscati, Avellino, Italia.
Di Micco L; UOC Nefrologia, Ospedale Moscati, Avellino, Italia.
La Manna G; Cattedra di Nefrologia, Università Alma Mater Studiorum - Policlinico Sant'Orsola Bologna, Italia.
Di Iorio B; UO Nefrologia Ospedale Landolfi, Solofra, Avellino, Italia.
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Źródło :
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia [G Ital Nefrol] 2018 May; Vol. 35 (3).
Typ publikacji :
Journal Article; Review
MeSH Terms :
Protein Carbamylation*
Cardiovascular Diseases/*etiology
Kidney Failure, Chronic/*metabolism
Urea/*metabolism
Alzheimer Disease/metabolism ; Amino Acids/therapeutic use ; Amyloidosis/metabolism ; Anemia, Sickle Cell/metabolism ; Animals ; Cardiovascular Diseases/metabolism ; Cataract/metabolism ; Chromatography, High Pressure Liquid ; Citrulline/analogs & derivatives ; Citrulline/analysis ; Clinical Trials as Topic ; Cyanates/metabolism ; Follow-Up Studies ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Lipoproteins/metabolism ; Renal Dialysis ; Tandem Mass Spectrometry ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Protein carbamylation exacerbates vascular calcification.
Autorzy :
Mori D; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Matsui I; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. Electronic address: .
Shimomura A; Department of Surgery, University of California-Irvine, Irvine, California, USA.
Hashimoto N; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Matsumoto A; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Shimada K; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Yamaguchi S; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Oka T; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Kubota K; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Yonemoto S; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Sakaguchi Y; Department of Comprehensive Kidney Disease Research, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
Takahashi A; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Shintani Y; Department of Medical Biochemistry, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Takashima S; Department of Medical Biochemistry, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Takabatake Y; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Hamano T; Department of Comprehensive Kidney Disease Research, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
Isaka Y; Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Pokaż więcej
Źródło :
Kidney international [Kidney Int] 2018 Jul; Vol. 94 (1), pp. 72-90. Date of Electronic Publication: 2018 Apr 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Carbamylation*
Kidney Failure, Chronic/*complications
Phosphoric Diester Hydrolases/*metabolism
Pyrophosphatases/*metabolism
Uremia/*complications
Vascular Calcification/*pathology
Animals ; Cell Line ; Disease Models, Animal ; Disease Progression ; Gene Knockdown Techniques ; Humans ; Kidney Failure, Chronic/blood ; Male ; Membrane Potential, Mitochondrial/physiology ; Muscle, Smooth, Vascular ; Oxidative Stress ; Phosphoric Diester Hydrolases/genetics ; Pyrophosphatases/genetics ; Rats ; Rats, Sprague-Dawley ; Uremia/blood ; Vascular Calcification/etiology
Czasopismo naukowe
Tytuł :
High-density lipoprotein carbamylation and dysfunction in vascular disease.
Autorzy :
Santana JM; Department of Anesthesiolgy, SUNY Downstate Medical Center, Brooklyn, NY, United States.
Brown CD; Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, United States, .
Pokaż więcej
Źródło :
Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2018 Jun 01; Vol. 23, pp. 2227-2234. Date of Electronic Publication: 2018 Jun 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Protein Carbamylation*
Atherosclerosis/*metabolism
Cardiovascular Diseases/*metabolism
Lipoproteins, HDL/*metabolism
Endothelial Cells/metabolism ; Humans ; Models, Biological ; Signal Transduction
Czasopismo naukowe

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