Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Ukraiński (UK)
Przejdź do strony domowej biblioteki Uniwersytet Ekonomiczny we Wrocławiu Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""Protein Conformation, alpha-Helical"" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-20 z 34
Tytuł:
Depolarizing Effects in Hydrogen Bond Energy in 3 10 -Helices Revealed by Quantum Chemical Analysis.
Autorzy:
Kondo HX; School of Regional Innovation and Social Design Engineering, Faculty of Engineering, Kitami Institute of Technology, Kitami 090-8507, Japan.; Department of Biomedical Information Sciences, Graduate School of Information Sciences, Hiroshima City University, Hiroshima 731-3194, Japan.; Laboratory for Computational Molecular Design, RIKEN Center for Biosystems Dynamics Research, 6-2-3, Furuedai, Suita 565-0874, Japan.
Nakamura H; Institute for Protein Research, Osaka University, Suita 565-0871, Japan.
Takano Y; Department of Biomedical Information Sciences, Graduate School of Information Sciences, Hiroshima City University, Hiroshima 731-3194, Japan.; Institute for Protein Research, Osaka University, Suita 565-0871, Japan.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 12; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 12.
Typ publikacji:
Journal Article
MeSH Terms:
Peptides*/chemistry
Density Functional Theory ; Hydrogen Bonding ; Models, Molecular ; Protein Conformation, alpha-Helical
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Insights Into the Micelle-Induced β-Hairpin-to-α-Helix Transition of a LytA-Derived Peptide by Photo-CIDNP Spectroscopy.
Autorzy:
Gomez MV; IRICA, Department of Inorganic, Organic and Biochemistry, Faculty of Chemical Sciences and Technologies, Universidad de Castilla-La Mancha (UCLM), Av. Camilo José Cela 10, 13071 Ciudad Real, Spain.
Ruiz-Castañeda M; IRICA, Department of Inorganic, Organic and Biochemistry, Faculty of Chemical Sciences and Technologies, Universidad de Castilla-La Mancha (UCLM), Av. Camilo José Cela 10, 13071 Ciudad Real, Spain.
Nitschke P; Institute of Organic Chemistry, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany.
Gschwind RM; Institute of Organic Chemistry, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany.
Jiménez MA; Departamento de Química-Física Biológica, Instituto de Química Física Rocasolano (IQFR-CSIC), Serrano 119, 28006 Madrid, Spain.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 22; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Micelles*
Protein Conformation, alpha-Helical*
Peptides/*chemistry
Tyrosine/*chemistry
Light ; Nuclear Magnetic Resonance, Biomolecular ; Photochemical Processes ; Spectrum Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structure-based derivation and optimization of YAP-like coactivator-derived peptides to selectively target TEAD family transcription factors by hydrocarbon stapling and cyclization.
Autorzy:
He B; Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wu T; Department of Thoracic Surgery, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
He P; Department of Cardiac Surgery, Southwest Hospital, Third Army Medical University, Chongqing, China.
Lv F; College of Bioengineering, Chongqing University, Chongqing, China.
Liu H; Department of Thoracic Surgery, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Pokaż więcej
Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2021 Jun; Vol. 97 (6), pp. 1129-1136. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Cycle Proteins/*chemistry
Hydrocarbons/*chemistry
Peptides/*chemistry
Transcription Factors/*metabolism
Amino Acid Sequence ; Binding Sites ; Cyclization ; Fluorescence Polarization ; Humans ; Molecular Dynamics Simulation ; Peptides/metabolism ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Isoforms/agonists ; Protein Isoforms/metabolism ; Transcription Factors/agonists ; Transcription Factors/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
X-ray Crystallographic Structure of α-Helical Peptide Stabilized by Hydrocarbon Stapling at i , i + 1 Positions.
Autorzy:
Makura Y; Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Ueda A; Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Kato T; Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, Osaka 569-1094, Japan.
Iyoshi A; Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Higuchi M; Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Doi M; Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, Osaka 569-1094, Japan.
Tanaka M; Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 May 19; Vol. 22 (10). Date of Electronic Publication: 2021 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Hydrocarbons/*chemistry
Peptides/*chemistry
Protein Stability/*drug effects
Alkenes/chemistry ; Amino Acid Sequence/genetics ; Amino Acids/chemistry ; Circular Dichroism/methods ; Crystallography, X-Ray/methods ; Oligopeptides/chemistry ; Proline/chemistry ; Protein Conformation, alpha-Helical/physiology ; Protein Structure, Secondary/physiology ; X-Rays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Studying the helical conformations of aspereline peptides.
Autorzy:
Blanár E; Institute of Biophysics, Biological Research Centre, Szeged, Hungary.
Leitgeb B; Institute of Biophysics, Biological Research Centre, Szeged, Hungary.
Pokaż więcej
Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2021 May; Vol. 97 (5), pp. 1029-1037. Date of Electronic Publication: 2021 Mar 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptides/*chemistry
Amino Acid Sequence ; Hydrogen Bonding ; Hypocreales/metabolism ; Molecular Dynamics Simulation ; Peptides/isolation & purification ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Folding
SCR Organism:
Trichoderma asperellum
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Virus-derived peptide inhibitors of the herpes simplex virus type 1 nuclear egress complex.
Autorzy:
Draganova EB; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA, 02111, USA.
Heldwein EE; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA, 02111, USA. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Feb 18; Vol. 11 (1), pp. 4206. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Nucleus/*genetics
Herpesvirus 1, Human/*genetics
Nuclear Proteins/*genetics
Peptides/*genetics
Viral Proteins/*genetics
Amino Acid Sequence ; Capsid Proteins/genetics ; Cytoplasm/genetics ; DNA Replication/genetics ; DNA, Viral/genetics ; Mutation/genetics ; Nuclear Envelope/genetics ; Protein Conformation, alpha-Helical/genetics ; Virus Replication/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Directed Electron Transfer in Flavin Peptides with Oligoproline-Type Helical Conformation as Models for Flavin-Functional Proteins.
Autorzy:
Wörner S; Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131, Karlsruhe, Germany.
Leier J; Institute of Physical Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 2, 76131, Karlsruhe, Germany.
Michenfelder NC; Institute of Physical Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 2, 76131, Karlsruhe, Germany.
Unterreiner AN; Institute of Physical Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 2, 76131, Karlsruhe, Germany.
Wagenknecht HA; Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131, Karlsruhe, Germany.
Pokaż więcej
Źródło:
ChemistryOpen [ChemistryOpen] 2020 Dec 11; Vol. 9 (12), pp. 1264-1269. Date of Electronic Publication: 2020 Dec 11 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Flavins/*chemistry
Peptides/*chemistry
Proteins/*chemistry
Electron Transport ; Models, Molecular ; Protein Conformation, alpha-Helical
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clustering and Fibril Formation during GNNQQNY Aggregation: A Molecular Dynamics Study.
Autorzy:
Szała-Mendyk B; Faculty of Chemistry, Adam Mickiewicz University, Umultowska 89b, 61-614 Poznań, Poland.
Molski A; Faculty of Chemistry, Adam Mickiewicz University, Umultowska 89b, 61-614 Poznań, Poland.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2020 Sep 24; Vol. 10 (10). Date of Electronic Publication: 2020 Sep 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amyloid/*ultrastructure
Peptide Termination Factors/*ultrastructure
Peptides/*chemistry
Prion Proteins/*ultrastructure
Saccharomyces cerevisiae Proteins/*ultrastructure
Amyloid/genetics ; Humans ; Kinetics ; Molecular Dynamics Simulation ; Peptide Termination Factors/genetics ; Peptides/genetics ; Prion Proteins/genetics ; Protein Aggregates/genetics ; Protein Aggregation, Pathological/genetics ; Protein Conformation ; Protein Conformation, alpha-Helical/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/ultrastructure ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A Diaminodiacid (DADA) Strategy for the Development of Disulfide Surrogate Peptides.
Autorzy:
Qi YK; Department of Medicinal Chemistry, School of Pharmacy, Qingdao University, Qingdao, 266021, China.; Tsinghua-Peking Center for Life Sciences, Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic and Systems Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Qu Q; Tsinghua-Peking Center for Life Sciences, Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic and Systems Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Bierer D; Bayer AG, Department of Medicinal Chemistry, Aprather Weg 18A, 42096, Wuppertal, Germany.
Liu L; Tsinghua-Peking Center for Life Sciences, Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic and Systems Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Pokaż więcej
Źródło:
Chemistry, an Asian journal [Chem Asian J] 2020 Sep 15; Vol. 15 (18), pp. 2793-2802. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Disulfides/*chemistry
Peptides/*chemistry
Antimicrobial Cationic Peptides/chemical synthesis ; Antimicrobial Cationic Peptides/chemistry ; Cyclization ; DNA-Binding Proteins/chemical synthesis ; DNA-Binding Proteins/chemistry ; Hydrocarbons/chemistry ; Peptides/chemical synthesis ; Peptides, Cyclic/chemical synthesis ; Peptides, Cyclic/chemistry ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Solid-Phase Synthesis Techniques
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stapled Peptides as HIF-1α/p300 Inhibitors: Helicity Enhancement in the Bound State Increases Inhibitory Potency.
Autorzy:
Hetherington K; School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.
Hegedus Z; School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.
Edwards TA; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.; School of Molecular and Cellular Biology, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.
Sessions RB; School of Biochemistry, University of Bristol, Medical Sciences Building, University Walk, Bristol, BS8 1TD, UK.; BrisSynBio, University of Bristol, Life Sciences Building, Tyndall Avenue, Bristol, BS8 1TQ, UK.
Nelson A; School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.
Wilson AJ; School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.
Pokaż więcej
Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Jun 18; Vol. 26 (34), pp. 7638-7646. Date of Electronic Publication: 2020 May 26.
Typ publikacji:
Journal Article
MeSH Terms:
E1A-Associated p300 Protein/*chemistry
Hypoxia-Inducible Factor 1, alpha Subunit/*chemistry
Peptides/*chemistry
Circular Dichroism ; E1A-Associated p300 Protein/antagonists & inhibitors ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/antagonists & inhibitors ; Protein Conformation, alpha-Helical
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cell Growth Stimulation, Cell Cycle Alternation, and Anti-Apoptosis Effects of Bovine Bone Collagen Hydrolysates Derived Peptides on MC3T3-E1 Cells Ex Vivo.
Autorzy:
Wang J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; School of Chemical Sciences, University of Chinese Academy of Sciences, Yuquan Road 19A, Beijing 100049, China.
Liu J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Guo Y; Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; School of Chemical Sciences, University of Chinese Academy of Sciences, Yuquan Road 19A, Beijing 100049, China.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 May 14; Vol. 25 (10). Date of Electronic Publication: 2020 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Bone and Bones/*chemistry
Collagen/*chemistry
ErbB Receptors/*chemistry
Peptides/*chemistry
Protein Hydrolysates/*chemistry
Amino Acid Sequence ; Animals ; Apoptosis/drug effects ; Binding Sites ; Cattle ; Cell Cycle/drug effects ; Cell Differentiation/drug effects ; Cell Division/drug effects ; Cell Line ; Cell Survival/drug effects ; Collagen/isolation & purification ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Mice ; Molecular Docking Simulation ; Osteoblasts/cytology ; Osteoblasts/drug effects ; Peptides/genetics ; Peptides/metabolism ; Peptides/pharmacology ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ambidextrous α,γ-Hybrid Peptide Foldamers.
Autorzy:
Misra R; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune, 411008, India.
George G; NMR Research Center, Indian Institute of Science, Bangalore, 560012, India.
Saseendran A; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune, 411008, India.
Raghothama S; NMR Research Center, Indian Institute of Science, Bangalore, 560012, India.
Gopi HN; Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune, 411008, India.
Pokaż więcej
Źródło:
Chemistry, an Asian journal [Chem Asian J] 2019 Dec 02; Vol. 14 (23), pp. 4408-4414. Date of Electronic Publication: 2019 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Peptides/*chemistry
Aminoisobutyric Acids/chemistry ; Crystallography, X-Ray ; Hydrogen Bonding ; Molecular Dynamics Simulation ; Protein Conformation, alpha-Helical ; Stereoisomerism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Aggregation State of Residual α -Helices and Their Influence on Physical Properties of S. c. ricini Native Fiber.
Autorzy:
Moseti KO; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan. .; Silk Materials Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan. .; National Sericulture Research Centre, Industrial Crops Research Institute, Kenya Agricultural and Livestock Research Organization, P.O. Box 7816-01000 Thika, Kenya. .
Yoshioka T; Silk Materials Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan. .
Kameda T; Silk Materials Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan. .
Nakazawa Y; Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan. .
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2019 Oct 17; Vol. 24 (20). Date of Electronic Publication: 2019 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Aggregates*
Bombyx/*chemistry
Fibroins/*ultrastructure
Peptides/*chemistry
Animals ; Bombyx/physiology ; Fibroins/isolation & purification ; Hot Temperature ; Larva/chemistry ; Larva/physiology ; Materials Testing ; Peptides/isolation & purification ; Pliability ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Tensile Strength
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stapled Peptides-A Useful Improvement for Peptide-Based Drugs.
Autorzy:
Moiola M; Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy. .
Memeo MG; Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy. .
Quadrelli P; Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy. .
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2019 Oct 10; Vol. 24 (20). Date of Electronic Publication: 2019 Oct 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Drug Design*
Peptides/*chemistry
Peptides/chemical synthesis ; Protein Conformation, alpha-Helical
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Immunomodulatory Functions of the Human Cathelicidin LL-37 (aa 13-31)-Derived Peptides are Associated with Predicted α-Helical Propensity and Hydrophobic Index.
Autorzy:
Hemshekhar M; Manitoba Centre for Proteomics and Systems Biology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3E3P4, Canada. .
Faiyaz S; Manitoba Centre for Proteomics and Systems Biology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3E3P4, Canada. .
Choi KG; Manitoba Centre for Proteomics and Systems Biology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3E3P4, Canada. .; Department of Immunology, University of Manitoba, Winnipeg, MB R3E 3P4, Canada. .
Krokhin OV; Manitoba Centre for Proteomics and Systems Biology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3E3P4, Canada. .; Department of Chemistry, University of Manitoba, Winnipeg, MB R3T 2N2, Canada. .
Mookherjee N; Manitoba Centre for Proteomics and Systems Biology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3E3P4, Canada. .; Department of Immunology, University of Manitoba, Winnipeg, MB R3E 3P4, Canada. .
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2019 Sep 18; Vol. 9 (9). Date of Electronic Publication: 2019 Sep 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Antimicrobial Cationic Peptides/*chemistry
Lipopolysaccharides/*adverse effects
Peptides/*pharmacology
Anti-Inflammatory Agents/chemistry ; Computer Simulation ; Cytokines/metabolism ; Down-Regulation ; Gene Expression Regulation/drug effects ; Humans ; Hydrophobic and Hydrophilic Interactions ; Interleukin 1 Receptor Antagonist Protein/metabolism ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/immunology ; Macrophages/drug effects ; Macrophages/immunology ; Peptides/chemistry ; Protein Conformation, alpha-Helical ; THP-1 Cells ; Cathelicidins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intragenic antimicrobial peptides (IAPs) from human proteins with potent antimicrobial and anti-inflammatory activity.
Autorzy:
Brand GD; Laboratório de Síntese e Análise de Biomoléculas, LSAB, Instituto de Química, Universidade de Brasília, Brasília, DF, Brasil.
Ramada MHS; Programa de Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília, DF, Brasil.; Programa de Pós-Graduação em Gerontologia, Universidade Católica de Brasília, Brasília, DF, Brasil.; Laboratório de Espectrometria de Massa, LEM, Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brasil.
Manickchand JR; Laboratório de Síntese e Análise de Biomoléculas, LSAB, Instituto de Química, Universidade de Brasília, Brasília, DF, Brasil.
Correa R; Laboratório de Imunologia e Inflamação, LIMI, Instituto de Biologia, Universidade de Brasília, Brasília, DF, Brasil.
Ribeiro DJS; Laboratório de Imunologia e Inflamação, LIMI, Instituto de Biologia, Universidade de Brasília, Brasília, DF, Brasil.
Santos MA; Laboratório de Ressonância Magnética Nuclear, LRMN, Instituto de Química, Universidade de Brasília, Brasília, DF, Brasil.
Vasconcelos AG; Núcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Campus Universitário Darcy Ribeiro, Universidade de Brasília, Brasília, DF, Brasil.
Abrão FY; Faculdade de Farmácia, FacUnicamps, Goiânia, GO, Brasil.
Prates MV; Laboratório de Espectrometria de Massa, LEM, Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brasil.
Murad AM; Laboratório de Espectrometria de Massa, LEM, Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brasil.
Cardozo Fh JL; Laboratório de Espectrometria de Massa, LEM, Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brasil.; Departamento de Fitopatologia, Instituto Mato-Grossense do Algodão, Primavera do Leste, MT, Brasil.
Leite JRSA; Núcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Campus Universitário Darcy Ribeiro, Universidade de Brasília, Brasília, DF, Brasil.
Magalhães KG; Laboratório de Imunologia e Inflamação, LIMI, Instituto de Biologia, Universidade de Brasília, Brasília, DF, Brasil.
Oliveira AL; Laboratório de Ressonância Magnética Nuclear, LRMN, Instituto de Química, Universidade de Brasília, Brasília, DF, Brasil.
Bloch C Jr; Laboratório de Espectrometria de Massa, LEM, Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brasil.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2019 Aug 06; Vol. 14 (8), pp. e0220656. Date of Electronic Publication: 2019 Aug 06 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Infective Agents/*chemical synthesis
Anti-Inflammatory Agents/*chemical synthesis
Peptides/*pharmacology
Animals ; Erythrocytes/drug effects ; Humans ; Liposomes/metabolism ; Macrophages/metabolism ; Mice ; Micelles ; Peptides/analysis ; Peptides/chemical synthesis ; Peptides/metabolism ; Protein Conformation, alpha-Helical ; Proteins/chemistry ; Solid-Phase Synthesis Techniques ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Improved Modeling of Peptidic Foldamers Using a Quantum Chemical Parametrization Based on Torsional Minimum Energy Path Matching.
Autorzy:
Wacha A; Institute of Materials and Environmental Chemistry Research Centre for Natural Sciences Hungarian Academy of Sciences H-1117 Budapest, Magyar tudósok körútja 2 Hungary.
Beke-Somfai T; Institute of Materials and Environmental Chemistry Research Centre for Natural Sciences Hungarian Academy of Sciences H-1117 Budapest, Magyar tudósok körútja 2 Hungary.
Nagy T; Institute of Materials and Environmental Chemistry Research Centre for Natural Sciences Hungarian Academy of Sciences H-1117 Budapest, Magyar tudósok körútja 2 Hungary.
Pokaż więcej
Źródło:
ChemPlusChem [Chempluschem] 2019 Jul; Vol. 84 (7), pp. 927-941. Date of Electronic Publication: 2019 Jul 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Quantum Theory*
Peptides/*chemistry
Hydrogen Bonding ; Models, Molecular ; Nuclear Magnetic Resonance, Biomolecular ; Protein Conformation, alpha-Helical ; Thermodynamics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability.
Autorzy:
Wolny M; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Batchelor M; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Bartlett GJ; School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.
Baker EG; School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.
Kurzawa M; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Knight PJ; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Dougan L; Astbury Centre for Structural Molecular Biology and School of Physics and Astronomy, University of Leeds, Leeds, LS2 9JT, UK.
Woolfson DN; School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.; School of Biochemistry, University of Bristol, Biomedical Sciences Building, Bristol, BS8 1TD, UK.; BrisSynBio, University of Bristol, Life Sciences Building, Bristol, BS8 1TQ, UK.
Paci E; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Peckham M; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2017 Mar 13; Vol. 7, pp. 44341. Date of Electronic Publication: 2017 Mar 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Conformation, alpha-Helical*
Arginine/*chemistry
Glutamic Acid/*chemistry
Lysine/*chemistry
Peptides/*chemistry
Amino Acid Sequence ; Hydrogen Bonding ; Models, Molecular ; Molecular Dynamics Simulation ; Protein Folding ; Protein Stability ; Thermodynamics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Concentration-dependent oligomerization of an alpha-helical antifreeze polypeptide makes it hyperactive.
Autorzy:
Mahatabuddin S; Graduate School of Life Science, Hokkaido University, Sapporo 060-0810, Japan.
Hanada Y; Graduate School of Life Science, Hokkaido University, Sapporo 060-0810, Japan.
Nishimiya Y; Bioproduction Research Institute, ioproduction Research Institute and OPERANDO Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Sapporo 062-8517, Japan.
Miura A; Bioproduction Research Institute, ioproduction Research Institute and OPERANDO Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Sapporo 062-8517, Japan.
Kondo H; Graduate School of Life Science, Hokkaido University, Sapporo 060-0810, Japan.; Bioproduction Research Institute, ioproduction Research Institute and OPERANDO Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Sapporo 062-8517, Japan.
Davies PL; Protein Function Discovery Group and Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, K7L 3N6, Canada.
Tsuda S; Graduate School of Life Science, Hokkaido University, Sapporo 060-0810, Japan.; Bioproduction Research Institute, ioproduction Research Institute and OPERANDO Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Sapporo 062-8517, Japan.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2017 Feb 13; Vol. 7, pp. 42501. Date of Electronic Publication: 2017 Feb 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Conformation, alpha-Helical*
Protein Multimerization*
Antifreeze Proteins/*chemistry
Antifreeze Proteins/*immunology
Peptides/*chemistry
Peptides/*immunology
Allergens/chemistry ; Allergens/immunology ; Animals ; Fish Proteins/chemistry ; Fish Proteins/immunology ; Hydrogen-Ion Concentration ; Protein Stability ; Solubility
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 34

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies