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Wyszukujesz frazę ""Protein Folding"" wg kryterium: Temat


Tytuł :
Misfolded amyloid-β-42 impairs the endosomal-lysosomal pathway.
Autorzy :
Marshall KE; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, BN1 9QG, UK.
Vadukul DM; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, BN1 9QG, UK.
Staras K; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, BN1 9QG, UK. .
Serpell LC; Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, BN1 9QG, UK. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Dec; Vol. 77 (23), pp. 5031-5043. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Folding*/drug effects
Amyloid beta-Peptides/*chemistry
Amyloid beta-Peptides/*metabolism
Endosomes/*metabolism
Lysosomes/*metabolism
Peptide Fragments/*chemistry
Peptide Fragments/*metabolism
Amyloid beta-Peptides/toxicity ; Animals ; Cells, Cultured ; Dynamins/metabolism ; Endocytosis/drug effects ; Endosomes/ultrastructure ; Hydrogen-Ion Concentration ; Lysosomes/drug effects ; Lysosomes/ultrastructure ; Neurons/drug effects ; Neurons/pathology ; Ovalbumin/metabolism ; Peptide Fragments/toxicity ; Rats
Czasopismo naukowe
Tytuł :
CD81 extracted in SMALP nanodiscs comprises two distinct protein populations within a lipid environment enriched with negatively charged headgroups.
Autorzy :
Ayub H; College of Health & Life Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK.
Clare M; College of Health & Life Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK.
Milic I; College of Health & Life Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK.
Chmel NP; Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Böning H; German Center for Infection Research (DZIF) Hannover-Braunschweig Site and Institute of Virology, Hannover Medical School, 30625 Hannover, Germany.
Devitt A; College of Health & Life Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK.
Krey T; German Center for Infection Research (DZIF) Hannover-Braunschweig Site and Institute of Virology, Hannover Medical School, 30625 Hannover, Germany; Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Luebeck, Luebeck, Germany; Centre for Structural Systems Biology (CSSB), Hamburg, Germany.
Bill RM; College of Health & Life Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK. Electronic address: .
Rothnie AJ; College of Health & Life Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Nov 01; Vol. 1862 (11), pp. 183419. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Molecular*
Protein Folding*
Tetraspanin 28/*chemistry
Crystallography, X-Ray ; Humans ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Saccharomycetales ; Tetraspanin 28/genetics ; Tetraspanin 28/metabolism
SCR Organism :
Komagataella pastoris
Czasopismo naukowe
Tytuł :
An Approach to comparing protein structures and origami models - Part 2. Multi-domain proteins.
Autorzy :
Azulay H; Koranit, 2018100, Israel. Electronic address: .
Pellach Leshem M; The Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, Henrietta Szold St. 8, POB 1589, Safed, Israel.
Qvit N; The Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, Henrietta Szold St. 8, POB 1589, Safed, Israel. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Nov 01; Vol. 1862 (11), pp. 183411. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Chemical*
Protein Folding*
Bacterial Outer Membrane Proteins/*chemistry
Protein Domains
Czasopismo naukowe
Tytuł :
A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels.
Autorzy :
Díaz-Franulic I; Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile, 2340000; .; Center for Bioinformatics and Integrative Biology, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile, 8370146.
Raddatz N; Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile, 2340000.
Castillo K; Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile, 2340000.
González-Nilo FD; Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile, 2340000.; Center for Bioinformatics and Integrative Biology, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile, 8370146.
Latorre R; Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile, 2340000; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Aug 18; Vol. 117 (33), pp. 20298-20304. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Protein Domains*
Protein Folding*
TRPM Cation Channels/*chemistry
Animals ; Cold Temperature ; Cryoelectron Microscopy ; Humans ; Ion Channel Gating ; Models, Molecular ; Mutagenesis, Site-Directed ; Mutation ; Oocytes ; Protein Conformation ; TRPM Cation Channels/metabolism ; Thermodynamics ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Conserved buried water molecules enable the β-trefoil architecture.
Autorzy :
Blaber M; Department of Biomedical Sciences, Florida State University, Tallahassee, Florida, USA.
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Źródło :
Protein science : a publication of the Protein Society [Protein Sci] 2020 Aug; Vol. 29 (8), pp. 1794-1802. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Molecular*
Protein Folding*
Proteins/*chemistry
Hydrophobic and Hydrophilic Interactions ; Protein Domains ; Protein Structure, Secondary
Czasopismo naukowe
Tytuł :
Synthesis runs counter to directional folding of a nascent protein domain.
Autorzy :
Chen X; CMDB Graduate Program, Johns Hopkins University, Baltimore, MD, USA.
Rajasekaran N; CMDB Graduate Program, Johns Hopkins University, Baltimore, MD, USA.
Liu K; CMDB Graduate Program, Johns Hopkins University, Baltimore, MD, USA.; Molecular Biology Program, Sloan Kettering Institute, New York, NY, USA.
Kaiser CM; Department of Biology, Johns Hopkins University, Baltimore, MD, USA. .; Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 09; Vol. 11 (1), pp. 5096. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Folding*
Peptide Elongation Factor G/*biosynthesis
Peptide Elongation Factor G/*chemistry
Luminescence ; Peptide Elongation Factor G/genetics ; Protein Biosynthesis ; Protein Domains ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Ribosomes/genetics ; Ribosomes/metabolism ; Single Molecule Imaging
Czasopismo naukowe
Tytuł :
GLN: a method to reveal unique properties of lasso type topology in proteins.
Autorzy :
Niemyska W; Faculty of Mathematics, Informatics and Mechanics, University of Warsaw, Banacha 2, 02-097, Warsaw, Poland.; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097, Warsaw, Poland.
Millett KC; Department of Mathematics, University of California Santa Barbara, Santa Barbara, CA, 93106, USA.
Sulkowska JI; Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097, Warsaw, Poland. .; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland. .
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 16; Vol. 10 (1), pp. 15186. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Molecular*
Models, Theoretical*
Protein Folding*
Proteins/*chemistry
Algorithms ; Animals ; Databases, Protein ; Datasets as Topic ; Humans ; Molecular Dynamics Simulation ; Protein Conformation
Czasopismo naukowe
Tytuł :
The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress.
Autorzy :
Zeinert RD; Department of Biochemistry and Molecular Biology, Molecular and Cellular Biology Program, University of Massachusetts Amherst, Amherst, MA 01003, USA.
Baniasadi H; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Tu BP; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Chien P; Department of Biochemistry and Molecular Biology, Molecular and Cellular Biology Program, University of Massachusetts Amherst, Amherst, MA 01003, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Sep 03; Vol. 79 (5), pp. 758-767.e6. Date of Electronic Publication: 2020 Aug 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Protein Folding*
Caulobacter crescentus/*metabolism
Nucleotides/*metabolism
Protease La/*metabolism
Bacterial Proteins/metabolism ; Caulobacter crescentus/enzymology ; DNA Transposable Elements ; Dideoxynucleosides/metabolism ; Gene Expression Regulation, Bacterial ; Nucleotide Deaminases/genetics ; Nucleotide Deaminases/metabolism ; Ribonucleotide Reductases/metabolism ; Stress, Physiological ; Transcription Factors/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Introducing Foldit Education Mode.
Autorzy :
Miller JA; Khoury College of Computer Sciences, Northeastern University, Boston, MA, USA.
Khatib F; Department of Computer and Information Science, University of Massachusetts Dartmouth, Dartmouth, MA, USA.
Hammond H; Department of Chemistry & Biochemistry and the Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, USA.
Cooper S; Khoury College of Computer Sciences, Northeastern University, Boston, MA, USA.
Horowitz S; Department of Chemistry & Biochemistry and the Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, USA. .
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2020 Sep; Vol. 27 (9), pp. 769-770.
Typ publikacji :
Letter; Research Support, N.I.H., Extramural
MeSH Terms :
Education, Distance*
Protein Folding*
Software*
Biochemistry/*education
Proteins/*chemistry
Humans ; Models, Molecular ; Peptides/chemistry ; Protein Conformation ; Video Games
Raport
Tytuł :
Expanding the space of protein geometries by computational design of de novo fold families.
Autorzy :
Pan X; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA. .; UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco, CA, USA.
Thompson MC; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.
Zhang Y; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.
Liu L; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.
Fraser JS; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.
Kelly MJS; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
Kortemme T; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA. .; UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco, CA, USA.; Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2020 Aug 28; Vol. 369 (6507), pp. 1132-1136.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Computer-Aided Design*
Protein Folding*
Protein Structure, Secondary*
Protein Engineering/*methods
Czasopismo naukowe
Tytuł :
Heterogeneous folding and stretched kinetics.
Autorzy :
Bilsel O; Microgradient Fluidics LLC, Worcester, MA 01605; .; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605.; Department of Chemistry, Stony Brook University, Stony Brook, NY 11794.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Aug 11; Vol. 117 (32), pp. 18915-18917. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Protein Folding*
Kinetics ; Protein Conformation ; Radiography ; X-Rays
Czasopismo naukowe
Tytuł :
Lipid membrane templated misfolding and self-assembly of intrinsically disordered tau protein.
Autorzy :
Majewski J; Division of Molecular and Cellular Biology, National Science Foundation, Alexandria, VA, 22314, USA.; Department of Chemical and Biological Engineering and Center for Biomedical Engineering, University of New Mexico, Albuquerque, NM, 87131, USA.; Theoretical Biology and Biophysics Division, Los Alamos National Laboratory, Los Alamos, NM, 87545, USA.
Jones EM; Nanoscience and Microsystems Engineering Graduate Program, University of New Mexico, Albuquerque, NM, 87131, USA.; Department of Chemical and Biological Engineering and Center for Biomedical Engineering, University of New Mexico, Albuquerque, NM, 87131, USA.
Vander Zanden CM; Department of Chemical and Biological Engineering and Center for Biomedical Engineering, University of New Mexico, Albuquerque, NM, 87131, USA.; Department of Chemistry and Biochemistry, University of Colorado at Colorado Springs, Colorado Springs, CO, 80918, USA.
Biernat J; Center for Neurodegenerative Diseases (DZNE), 53127, Bonn, Germany.; CAESAR Research Center, 53175, Bonn, Germany.
Mandelkow E; Center for Neurodegenerative Diseases (DZNE), 53127, Bonn, Germany.; CAESAR Research Center, 53175, Bonn, Germany.
Chi EY; Department of Chemical and Biological Engineering and Center for Biomedical Engineering, University of New Mexico, Albuquerque, NM, 87131, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Aug 07; Vol. 10 (1), pp. 13324. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Folding*
Protein Multimerization*
Intrinsically Disordered Proteins/*chemistry
Lipid Bilayers/*chemistry
tau Proteins/*chemistry
Humans ; Intrinsically Disordered Proteins/genetics ; Protein Conformation, beta-Strand ; tau Proteins/genetics
Czasopismo naukowe
Tytuł :
Cryo-electron microscopy structure of CLHM1 ion channel from Caenorhabditis elegans.
Autorzy :
Yang W; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Wang Y; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Guo J; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
He L; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Zhou Y; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Zheng H; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Liu Z; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Zhu P; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Zhang XC; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
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Źródło :
Protein science : a publication of the Protein Society [Protein Sci] 2020 Aug; Vol. 29 (8), pp. 1803-1815. Date of Electronic Publication: 2020 Jun 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Folding*
Caenorhabditis elegans/*ultrastructure
Caenorhabditis elegans Proteins/*ultrastructure
Calcium Channels/*ultrastructure
Animals ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/metabolism ; Calcium Channels/metabolism ; Cryoelectron Microscopy ; Protein Domains
Czasopismo naukowe
Tytuł :
A glance into the evolution of template-free protein structure prediction methodologies.
Autorzy :
Dhingra S; Université de Nantes, CNRS, UFIP, UMR6286, F-44000, Nantes, France.
Sowdhamini R; Computational Approaches to Protein Science (CAPS), National Centre for Biological Sciences (NCBS), Tata Institute for Fundamental Research (TIFR), Bangalore, 560-065, India.
Cadet F; University of Paris, BIGR-Biologie Intégrée du Globule Rouge, Inserm, UMR_S1134, Paris, F-75015, France; Laboratory of Excellence GR-Ex, Boulevard du Montparnasse, Paris, F-75015, France; DSIMB, UMR_S1134, BIGR, Inserm, Faculty of Sciences and Technology, University of La Reunion, Saint-Denis, F-97715, France.
Offmann B; Université de Nantes, CNRS, UFIP, UMR6286, F-44000, Nantes, France. Electronic address: .
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Źródło :
Biochimie [Biochimie] 2020 Aug; Vol. 175, pp. 85-92. Date of Electronic Publication: 2020 May 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Algorithms*
Computational Biology*
Databases, Protein*
Models, Molecular*
Protein Folding*
Proteins/*chemistry
Protein Conformation ; Proteins/genetics
Czasopismo naukowe
Tytuł :
Mechanistic modeling of chromatin folding to understand function.
Autorzy :
Brackey CA; SUPA School of Physics and Astronomy, University of Edinburgh, Edinburgh, UK.
Marenduzzo D; SUPA School of Physics and Astronomy, University of Edinburgh, Edinburgh, UK. .
Gilbert N; MRC Human Genetics Unit, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK. .
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Źródło :
Nature methods [Nat Methods] 2020 Aug; Vol. 17 (8), pp. 767-775. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Computer Simulation*
Models, Chemical*
Protein Folding*
Chromatin/*chemistry
Chromatin/*physiology
Animals
Czasopismo naukowe
Tytuł :
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria.
Autorzy :
Horne JE; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.; Department of Biochemistry, University of Oxford, Oxford, United Kingdom.
Brockwell DJ; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Radford SE; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Jul 24; Vol. 295 (30), pp. 10340-10367. Date of Electronic Publication: 2020 Jun 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Protein Folding*
Bacterial Outer Membrane Proteins/*metabolism
Cell Membrane/*metabolism
Gram-Negative Bacteria/*metabolism
Lipid Bilayers/*metabolism
Protein Multimerization/*physiology
Czasopismo naukowe
Tytuł :
Cotranslational folding stimulates programmed ribosomal frameshifting in the alphavirus structural polyprotein.
Autorzy :
Harrington HR; Department of Chemistry, Indiana University, Bloomington, Indiana 47405.
Zimmer MH; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125.
Chamness LM; Department of Chemistry, Indiana University, Bloomington, Indiana 47405.
Nash V; Department of Chemistry, Indiana University, Bloomington, Indiana 47405.
Penn WD; Department of Chemistry, Indiana University, Bloomington, Indiana 47405.
Miller TF 3rd; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125 .
Mukhopadhyay S; Department of Biology, Indiana University, Bloomington, Indiana 47405 .
Schlebach JP; Department of Chemistry, Indiana University, Bloomington, Indiana 47405 .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 May 15; Vol. 295 (20), pp. 6798-6808. Date of Electronic Publication: 2020 Mar 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Frameshifting, Ribosomal*
Protein Biosynthesis*
Protein Folding*
Alphavirus/*classification
Polyproteins/*biosynthesis
Sindbis Virus/*metabolism
Viral Proteins/*biosynthesis
Alphavirus/chemistry ; HEK293 Cells ; Humans ; Sindbis Virus/genetics
Czasopismo naukowe
Tytuł :
Modulated Scanning Fluorimetry Can Quickly Assess Thermal Protein Unfolding Reversibility in Microvolume Samples.
Autorzy :
Svilenov HL; Department of Pharmacy, Ludwig-Maximilians-University, Butenandtstr. 5, 81377 Munich, Germany.
Menzen T; Coriolis Pharma Research GmbH, Fraunhoferstr. 18 b, 82152 Martinsried, Germany.
Richter K; Coriolis Pharma Research GmbH, Fraunhoferstr. 18 b, 82152 Martinsried, Germany.
Winter G; Department of Pharmacy, Ludwig-Maximilians-University, Butenandtstr. 5, 81377 Munich, Germany.
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Źródło :
Molecular pharmaceutics [Mol Pharm] 2020 Jul 06; Vol. 17 (7), pp. 2638-2647. Date of Electronic Publication: 2020 May 27.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Folding*
Protein Unfolding*
Fluorometry/*methods
Proteins/*chemistry
Calorimetry, Differential Scanning ; Fluorescent Dyes/chemistry ; Hot Temperature ; Hydrogen-Ion Concentration ; Kinetics ; Muramidase/chemistry ; Ovalbumin/chemistry ; Polyethylene Glycols/chemistry ; Protein Denaturation ; Software ; Thermodynamics ; Trastuzumab/chemistry ; Ubiquitin/chemistry
Czasopismo naukowe
Tytuł :
Chaperone action of a cofactor in protein folding.
Autorzy :
Chen C; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA.
Park C; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA.; Interdisciplinary Life Science Graduate Program, Purdue University, West Lafayette, Indiana, USA.; Bindley Bioscience Center, Purdue University, West Lafayette, Indiana, USA.
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Źródło :
Protein science : a publication of the Protein Society [Protein Sci] 2020 Jul; Vol. 29 (7), pp. 1667-1678. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Protein Folding*
Adenosine Triphosphate/*chemistry
Escherichia coli/*enzymology
Escherichia coli Proteins/*chemistry
Glyceraldehyde-3-Phosphate Dehydrogenases/*chemistry
Molecular Chaperones/*chemistry
NAD/*chemistry
Czasopismo naukowe

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