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Wyszukujesz frazę ""Protein Folding"" wg kryterium: Temat


Tytuł :
Single-Molecule Force Spectroscopy of Protein Folding.
Autorzy :
Petrosyan R; Department of Physics, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Narayan A; Department of Physics, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Woodside MT; Department of Physics, University of Alberta, Edmonton, AB T6G 2E1, Canada.
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Oct 01; Vol. 433 (20), pp. 167207. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Protein Folding*
Proteins/*chemistry
Single Molecule Imaging/*methods
Animals ; Humans ; Models, Molecular
Czasopismo naukowe
Tytuł :
The local topological free energy of proteins.
Autorzy :
Baldwin Q; Department of Biology, Tuskegee University, 1200 W Montgomery Rd, Tuskegee, AL 36088, USA.
Panagiotou E; Department of Mathematics and SimCenter, University of Tennessee at Chattanooga, 615 McCallie Ave, Chattanooga, TN 37403, USA. Electronic address: .
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Źródło :
Journal of theoretical biology [J Theor Biol] 2021 Nov 21; Vol. 529, pp. 110854. Date of Electronic Publication: 2021 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Protein Folding*
Proteins*
Amino Acids ; Entropy ; Protein Conformation
Czasopismo naukowe
Tytuł :
Bimolecular quenching of tryptophan fluorescence in a membrane protein: Evolution of local solvation and environment during folding into a bilayer.
Autorzy :
Asamoto DK; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, United States.
Kozachenko IA; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, United States.
López-Peña I; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, United States.
Kim JE; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, United States. Electronic address: .
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Źródło :
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2021 Nov 05; Vol. 260, pp. 119919. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Folding*
Tryptophan*
Kinetics ; Lipid Bilayers ; Spectrometry, Fluorescence
Czasopismo naukowe
Tytuł :
AlphaFold - A Personal Perspective on the Impact of Machine Learning.
Autorzy :
Fersht AR; MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Oct 01; Vol. 433 (20), pp. 167088. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Machine Learning*
Protein Folding*
Proteins/*chemistry
Animals ; Chymotrypsin/chemistry ; Humans ; Models, Molecular ; Protein Conformation ; Software ; Trypsin/chemistry
Czasopismo naukowe
Tytuł :
The Protein Folding Problem: The Role of Theory.
Autorzy :
Nassar R; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, NY, USA; Department of Chemistry, Stony Brook University, Stony Brook, NY, USA.
Dignon GL; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, NY, USA.
Razban RM; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, NY, USA.
Dill KA; Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, NY, USA; Department of Chemistry, Stony Brook University, Stony Brook, NY, USA; Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY, USA. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Oct 01; Vol. 433 (20), pp. 167126. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Protein Folding*
Proteins/*chemistry
Animals ; Humans ; Intrinsically Disordered Proteins/chemistry ; Models, Molecular ; Protein Aggregates ; Protein Conformation
Czasopismo naukowe
Tytuł :
The Proteome Folding Problem and Cellular Proteostasis.
Autorzy :
Powers ET; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: .
Gierasch LM; Departments of Biochemistry & Molecular Biology and Chemistry, University of Massachusetts-Amherst, Amherst, MA 01003, USA. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Oct 01; Vol. 433 (20), pp. 167197. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Protein Folding*
Proteostasis*
Proteome/*chemistry
Animals ; Humans ; Molecular Chaperones/chemistry ; Molecular Chaperones/metabolism ; Proteome/metabolism
Czasopismo naukowe
Tytuł :
Entropy-Enthalpy Compensations Fold Proteins in Precise Ways.
Autorzy :
Li J; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.
Hou C; School of Electronics and Information Engineering, Harbin Institute of Technology, Harbin 150080, China.
Ma X; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.
Guo S; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.
Zhang H; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.
Shi L; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.
Liao C; School of Electronics and Information Engineering, Harbin Institute of Technology, Harbin 150080, China.
Zheng B; Key Laboratory of Functional Inorganic Material Chemistry (Ministry of Education), School of Chemistry and Materials Science, Heilongjiang University, Harbin 150001, China.
Ye L; School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW 2006, Australia.
Yang L; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.; School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW 2006, Australia.
He X; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.; Shenzhen STRONG Advanced Materials Research Institute Co., Ltd., Shenzhen 518035, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 06; Vol. 22 (17). Date of Electronic Publication: 2021 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Entropy*
Hydrogen Bonding*
Protein Folding*
Thermodynamics*
Proteins/*chemistry
Amino Acid Sequence ; Amino Acids/chemistry ; Hydrophobic and Hydrophilic Interactions ; Models, Molecular ; Peptides/chemistry ; Protein Conformation, alpha-Helical ; Protein Stability
Czasopismo naukowe
Tytuł :
Dissecting Inter-domain Cooperativity in the Folding of a Multi Domain Protein.
Autorzy :
Laursen L; Department of Medical Biochemistry and Microbiology, Uppsala University, BMC Box 582, SE-75123 Uppsala, Sweden.
Gianni S; Istituto Pasteur-Fondazione Cenci Bolognetti and Istituto di Biologia e Patologia Molecolari del CNR, Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli,' Sapienza Università di Roma, 00185 Rome, Italy. Electronic address: .
Jemth P; Department of Medical Biochemistry and Microbiology, Uppsala University, BMC Box 582, SE-75123 Uppsala, Sweden. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Sep 03; Vol. 433 (18), pp. 167148. Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
PDZ Domains*
Protein Folding*
src Homology Domains*
Disks Large Homolog 4 Protein/*chemistry
Binding Sites ; Humans ; Kinetics ; Models, Molecular ; Protein Binding ; Protein Conformation
Czasopismo naukowe
Tytuł :
The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.
Autorzy :
Romero-Romero S; Laboratorio de Fisicoquímica e Ingeniería de Proteínas, Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510 Mexico City, Mexico; Department of Biochemistry, University of Bayreuth, 95447 Bayreuth, Germany.
Costas M; Laboratorio de Biofisicoquímica, Departamento de Fisicoquímica, Facultad de Química, Universidad Nacional Autónoma de México, 04510 Mexico City, Mexico.
Silva Manzano DA; Department of Biochemistry, University of Washington, 98195 Seattle, USA; Institute for Protein Design, University of Washington, 98195 Seattle, USA.
Kordes S; Department of Biochemistry, University of Bayreuth, 95447 Bayreuth, Germany.
Rojas-Ortega E; Laboratorio de Fisicoquímica e Ingeniería de Proteínas, Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510 Mexico City, Mexico.
Tapia C; Laboratorio de Fisicoquímica e Ingeniería de Proteínas, Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510 Mexico City, Mexico.
Guerra Y; Laboratorio de Fisicoquímica e Ingeniería de Proteínas, Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510 Mexico City, Mexico.
Shanmugaratnam S; Department of Biochemistry, University of Bayreuth, 95447 Bayreuth, Germany.
Rodríguez-Romero A; Instituto de Química, Universidad Nacional Autónoma de México, 04510 Mexico City, Mexico.
Baker D; Department of Biochemistry, University of Washington, 98195 Seattle, USA; Institute for Protein Design, University of Washington, 98195 Seattle, USA. Electronic address: .
Höcker B; Department of Biochemistry, University of Bayreuth, 95447 Bayreuth, Germany. Electronic address: .
Fernández-Velasco DA; Laboratorio de Fisicoquímica e Ingeniería de Proteínas, Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510 Mexico City, Mexico. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Sep 03; Vol. 433 (18), pp. 167153. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Conformation, alpha-Helical*
Protein Conformation, beta-Strand*
Protein Folding*
Protein Stability*
Proteins/*chemistry
Evolution, Molecular ; Hydrophobic and Hydrophilic Interactions ; Models, Molecular ; Temperature
Czasopismo naukowe
Tytuł :
The protein hydration layer in high glucose concentration: Dynamical responses in folded and intrinsically disordered dimeric states.
Autorzy :
Ghosh B; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, 741 246, India.
Sengupta N; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, 741 246, India. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Nov 05; Vol. 577, pp. 124-129. Date of Electronic Publication: 2021 Sep 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Dynamics Simulation*
Protein Folding*
Protein Multimerization*
Glucose/*chemistry
Intrinsically Disordered Proteins/*chemistry
Proteins/*chemistry
Amyloid beta-Peptides/chemistry ; Amyloid beta-Peptides/metabolism ; Glucose/metabolism ; Hydrophobic and Hydrophilic Interactions ; Intrinsically Disordered Proteins/metabolism ; Protein Conformation ; Proteins/metabolism ; Ubiquitin/chemistry ; Ubiquitin/metabolism ; Water/chemistry
Czasopismo naukowe
Tytuł :
Single-molecule optical tweezers reveals folding steps of the domain swapping mechanism of a protein.
Autorzy :
Bustamante A; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile.
Rivera R; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile.
Floor M; Bioinformatics and Medical Statistics Group, Faculty of Science and Technology, Universitat de Vic - Universitat Central de Catalunya, Vic, Spain; Department of Basic Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.
Babul J; Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.
Baez M; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile. Electronic address: .
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Źródło :
Biophysical journal [Biophys J] 2021 Nov 02; Vol. 120 (21), pp. 4809-4818. Date of Electronic Publication: 2021 Sep 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Optical Tweezers*
Protein Folding*
Forkhead Transcription Factors/metabolism ; Humans ; Macromolecular Substances ; Protein Domains ; Proteins ; Repressor Proteins/metabolism
Czasopismo naukowe
Tytuł :
Small Neutral Crowding Solute Effects on Protein Folding Thermodynamic Stability and Kinetics.
Autorzy :
Contessoto VG; Department of Physics, Institute of Biosciences, Letters and Exact Sciences, São Paulo State University, São José do Rio Preto 15054-000, Brazil.
Ferreira PHB; Laboratório de Biofísica Teórica, Departamento de Física, Instituto de Ciências Exatas, Naturais e Educação, Universidade Federal do Triângulo Mineiro, Uberaba 38064-200, Brazil.
Chahine J; Department of Physics, Institute of Biosciences, Letters and Exact Sciences, São Paulo State University, São José do Rio Preto 15054-000, Brazil.
Leite VBP; Department of Physics, Institute of Biosciences, Letters and Exact Sciences, São Paulo State University, São José do Rio Preto 15054-000, Brazil.
Oliveira RJ; Laboratório de Biofísica Teórica, Departamento de Física, Instituto de Ciências Exatas, Naturais e Educação, Universidade Federal do Triângulo Mineiro, Uberaba 38064-200, Brazil.
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Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2021 Oct 28; Vol. 125 (42), pp. 11673-11686. Date of Electronic Publication: 2021 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Folding*
Kinetics ; Protein Stability ; Solutions ; Thermodynamics
Czasopismo naukowe
Tytuł :
AlphaFold 2: Why It Works and Its Implications for Understanding the Relationships of Protein Sequence, Structure, and Function.
Autorzy :
Skolnick J; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Gao M; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Zhou H; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Singh S; Twilight Design, 4 Adams Road, Kendall Park, New Jersey 08824, United States.
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Źródło :
Journal of chemical information and modeling [J Chem Inf Model] 2021 Oct 25; Vol. 61 (10), pp. 4827-4831. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Folding*
Proteins*
Algorithms ; Amino Acid Sequence
Czasopismo naukowe
Tytuł :
Temperature and Guanidine Hydrochloride Effects on the Folding Thermodynamics of WW Domain and Variants.
Autorzy :
Qin M; Biophysics Program, Institute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742, United States.; National Laboratory of Solid State Microstructure and Department of Physics, Nanjing University, and Collaborative Innovation Center of Advanced Microstructures, Nanjing 210093, China.
Denesyuk N; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States.
Liu Z; Department of Physics, Beijing Normal University, Beijing 100875, China.
Wang W; School of Physics, Nanjing University, Nanjing 210093, China.
Thirumalai D; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States.
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Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2021 Oct 21; Vol. 125 (41), pp. 11386-11391. Date of Electronic Publication: 2021 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Folding*
Guanidine ; Kinetics ; Protein Denaturation ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Temperature ; Thermodynamics ; WW Domains
Czasopismo naukowe
Tytuł :
Breakthrough Discovery in Protein Structure Prediction and the Promise of New Treatments.
Autorzy :
Komaroff AL; Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
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Źródło :
JAMA [JAMA] 2021 Oct 12; Vol. 326 (14), pp. 1369-1370.
Typ publikacji :
Historical Article; Journal Article
MeSH Terms :
Protein Folding*
Protein Structure, Tertiary*
Artificial Intelligence ; Biology/history ; History, 20th Century ; History, 21st Century ; Humans ; Protein Conformation
Czasopismo naukowe
Tytuł :
Trypsinogen and chymotrypsinogen: the mysterious hyper-reactivity of selected cysteines is still present after their divergent evolution.
Autorzy :
Cattani G; Department of Chemical Sciences and Technologies, University of Rome Tor Vergata, Italy.
Bocedi A; Department of Chemical Sciences and Technologies, University of Rome Tor Vergata, Italy.
Gambardella G; Department of Chemical Sciences and Technologies, University of Rome Tor Vergata, Italy.
Iavarone F; Dipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica Sacro Cuore, Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Boroumand M; Laboratorio di Proteomica, Centro Europeo di Ricerca sul Cervello, IRCCS Fondazione Santa Lucia, Rome, Italy.
Castagnola M; Laboratorio di Proteomica, Centro Europeo di Ricerca sul Cervello, IRCCS Fondazione Santa Lucia, Rome, Italy.
Ricci G; Department of Chemical Sciences and Technologies, University of Rome Tor Vergata, Italy.
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Źródło :
The FEBS journal [FEBS J] 2021 Oct; Vol. 288 (20), pp. 6003-6018. Date of Electronic Publication: 2021 May 30.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Protein Folding*
Chymotrypsinogen/*chemistry
Cysteine/*chemistry
Disulfides/*chemistry
Glutathione/*chemistry
Trypsinogen/*chemistry
Chymotrypsinogen/metabolism ; Cysteine/metabolism ; Disulfides/metabolism ; Glutathione/metabolism ; Humans ; Oxidation-Reduction ; Trypsinogen/metabolism
Czasopismo naukowe
Tytuł :
Structure-based classification of tauopathies.
Autorzy :
Shi Y; MRC Laboratory of Molecular Biology, Cambridge, UK.
Zhang W; MRC Laboratory of Molecular Biology, Cambridge, UK.
Yang Y; MRC Laboratory of Molecular Biology, Cambridge, UK.
Murzin AG; MRC Laboratory of Molecular Biology, Cambridge, UK.
Falcon B; MRC Laboratory of Molecular Biology, Cambridge, UK.
Kotecha A; Thermo Fisher Scientific, Eindhoven, The Netherlands.
van Beers M; Thermo Fisher Scientific, Eindhoven, The Netherlands.
Tarutani A; Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Kametani F; Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Garringer HJ; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Vidal R; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Hallinan GI; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Lashley T; Department of Neurodegenerative Disease and Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.
Saito Y; Department of Neuropathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Murayama S; Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, University of Osaka, Osaka, Japan.
Yoshida M; Institute for Medical Science of Aging, Aichi Medical University, Nagakute, Japan.
Tanaka H; Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan.
Kakita A; Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan.
Ikeuchi T; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.
Robinson AC; Clinical Sciences Building, University of Manchester, Salford Royal Foundation Trust, Salford, UK.
Mann DMA; Clinical Sciences Building, University of Manchester, Salford Royal Foundation Trust, Salford, UK.
Kovacs GG; Department of Laboratory Medicine and Pathobiology and Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Institute of Neurology, Medical University of Vienna, Vienna, Austria.
Revesz T; Department of Neurodegenerative Disease and Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.
Ghetti B; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Hasegawa M; Department of Brain and Neurosciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Goedert M; MRC Laboratory of Molecular Biology, Cambridge, UK. .
Scheres SHW; MRC Laboratory of Molecular Biology, Cambridge, UK. .
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Źródło :
Nature [Nature] 2021 Oct; Vol. 598 (7880), pp. 359-363. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cryoelectron Microscopy*
Protein Folding*
Tauopathies/*classification
tau Proteins/*chemistry
tau Proteins/*ultrastructure
Aged ; Aged, 80 and over ; Amino Acid Sequence ; Dementia/genetics ; Denmark ; Female ; Humans ; Introns/genetics ; Male ; Middle Aged ; Models, Molecular ; Mutation ; Protein Isoforms/chemistry ; Protein Isoforms/ultrastructure ; Supranuclear Palsy, Progressive ; Tauopathies/pathology ; United Kingdom
Czasopismo naukowe
Tytuł :
AlphaFold and the amyloid landscape.
Autorzy :
Pinheiro F; Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain; Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain. Electronic address: .
Santos J; Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain; Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
Ventura S; Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain; Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Oct 01; Vol. 433 (20), pp. 167059. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Protein Aggregates*
Protein Folding*
Amyloid/*chemistry
Amyloid/metabolism ; Amyloidosis/metabolism ; Animals ; Humans ; Models, Molecular ; Protein Aggregation, Pathological/metabolism ; Protein Conformation ; Software
Czasopismo naukowe
Tytuł :
AlphaFold and Implications for Intrinsically Disordered Proteins.
Autorzy :
Ruff KM; Department of Biomedical Engineering and Center for Science & Engineering of Living Systems (CSELS), Washington University in St. Louis, Campus Box 1097, St. Louis, MO 63130, USA.
Pappu RV; Department of Biomedical Engineering and Center for Science & Engineering of Living Systems (CSELS), Washington University in St. Louis, Campus Box 1097, St. Louis, MO 63130, USA. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Oct 01; Vol. 433 (20), pp. 167208. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Protein Folding*
Intrinsically Disordered Proteins/*chemistry
Animals ; Computational Biology ; Deep Learning ; Humans ; Models, Molecular ; Protein Conformation ; Proteome/chemistry
Czasopismo naukowe

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