Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Ukraiński (UK)
Przejdź do strony domowej biblioteki Uniwersytet Ekonomiczny we Wrocławiu Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""Protein Isoforms"" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-20 z 2236
Tytuł:
De novo annotation of lncRNA HOTAIR transcripts by long-read RNA capture-seq reveals a differentiation-driven isoform switch.
Autorzy:
Potolitsyna E; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112, 0317, Oslo, Blindern, Norway.
Hazell Pickering S; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112, 0317, Oslo, Blindern, Norway.; Department of Immunology and Transfusion Medicine, Oslo University Hospital, 0424, Oslo, Norway.
Tooming-Klunderud A; Centre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Oslo, Norway.
Collas P; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112, 0317, Oslo, Blindern, Norway. .; Department of Immunology and Transfusion Medicine, Oslo University Hospital, 0424, Oslo, Norway. .
Briand N; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112, 0317, Oslo, Blindern, Norway. .; Department of Immunology and Transfusion Medicine, Oslo University Hospital, 0424, Oslo, Norway. .
Pokaż więcej
Źródło:
BMC genomics [BMC Genomics] 2022 Sep 17; Vol. 23 (1), pp. 658. Date of Electronic Publication: 2022 Sep 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*/genetics
Protein Isoforms*/genetics
Protein Isoforms*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Biomarkers ; Histone Demethylases ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells.
Autorzy:
Melani RD; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Gerbasi VR; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Anderson LC; National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, USA.
Sikora JW; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Toby TK; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Hutton JE; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Butcher DS; National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, USA.
Negrão F; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Seckler HS; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Srzentić K; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Fornelli L; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Camarillo JM; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
LeDuc RD; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Cesnik AJ; Department of Genetics, Stanford University, Stanford, CA, USA.; Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH-Royal Institute of Technology, Stockholm, Sweden.
Lundberg E; Department of Genetics, Stanford University, Stanford, CA, USA.; Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH-Royal Institute of Technology, Stockholm, Sweden.
Greer JB; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Fellers RT; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Robey MT; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
DeHart CJ; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Forte E; Proteomics Center of Excellence, Northwestern University, Evanston, IL, USA.; Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Hendrickson CL; National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, USA.
Abbatiello SE; Thermo Fisher Scientific, Cambridge, MA, USA.
Thomas PM; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Kokaji AI; STEMCELL Technologies Inc., Vancouver, BC, Canada.
Levitsky J; Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Kelleher NL; Department of Molecular Biosciences, Department of Chemistry, and the Feinberg School of Medicine, Northwestern University, Evanston, IL, USA.; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2022 Jan 28; Vol. 375 (6579), pp. 411-418. Date of Electronic Publication: 2022 Jan 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Databases, Protein*
Blood Cells/*chemistry
Blood Proteins/*chemistry
Bone Marrow Cells/*chemistry
Protein Isoforms/*chemistry
Proteome/*chemistry
Alternative Splicing ; B-Lymphocytes/chemistry ; Blood Proteins/genetics ; Cell Lineage ; Humans ; Leukocytes, Mononuclear/chemistry ; Liver Transplantation ; Plasma/chemistry ; Protein Isoforms/genetics ; Protein Processing, Post-Translational ; Proteomics ; T-Lymphocytes/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Translation of human Δ133p53 mRNA and its targeting by antisense oligonucleotides complementary to the 5'-terminal region of this mRNA.
Autorzy:
Żydowicz-Machtel P; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Dutkiewicz M; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Swiatkowska A; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Gurda-Woźna D; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Ciesiołka J; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2021 Sep 07; Vol. 16 (9), pp. e0256938. Date of Electronic Publication: 2021 Sep 07 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oligonucleotides, Antisense/*pharmacology
Protein Biosynthesis/*drug effects
Protein Isoforms/*genetics
Tumor Suppressor Protein p53/*genetics
Cell Survival/drug effects ; Codon, Initiator/antagonists & inhibitors ; HCT116 Cells ; Humans ; Introns/genetics ; Protein Isoforms/antagonists & inhibitors ; RNA, Messenger/antagonists & inhibitors ; Transcription Initiation Site/drug effects ; Tumor Suppressor Protein p53/antagonists & inhibitors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
TREM-1 isoforms in bacterial infections: to immune modulation and beyond.
Autorzy:
Matos AO; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil.
Dantas PHDS; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil.
Silva-Sales M; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil.
Sales-Campos H; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil.
Pokaż więcej
Źródło:
Critical reviews in microbiology [Crit Rev Microbiol] 2021 May; Vol. 47 (3), pp. 290-306. Date of Electronic Publication: 2021 Jan 31.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Bacterial Infections/*immunology
Protein Isoforms/*immunology
Triggering Receptor Expressed on Myeloid Cells-1/*immunology
Animals ; Bacteria/genetics ; Bacteria/immunology ; Bacterial Infections/genetics ; Bacterial Infections/microbiology ; Biomarkers/analysis ; Humans ; Immunity ; Protein Isoforms/genetics ; Triggering Receptor Expressed on Myeloid Cells-1/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Isoform-Specific Role of GSK-3 in High Fat Diet Induced Obesity and Glucose Intolerance.
Autorzy:
Gupte M; Department of Biology, Austin Peay State University, Clarksville, TN 37044, USA.
Tousif S; Division of Cardiovascular Diseases, The University of Alabama at Birmingham (UAB), Birmingham, AL 35233, USA.
Lemon JJ; Department of Biology, Austin Peay State University, Clarksville, TN 37044, USA.
Toro Cora A; Division of Cardiovascular Diseases, The University of Alabama at Birmingham (UAB), Birmingham, AL 35233, USA.
Umbarkar P; Division of Cardiovascular Diseases, The University of Alabama at Birmingham (UAB), Birmingham, AL 35233, USA.
Lal H; Division of Cardiovascular Diseases, The University of Alabama at Birmingham (UAB), Birmingham, AL 35233, USA.
Pokaż więcej
Źródło:
Cells [Cells] 2022 Feb 05; Vol. 11 (3). Date of Electronic Publication: 2022 Feb 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Diet, High-Fat/*adverse effects
Glucose Intolerance/*etiology
Glycogen Synthase Kinase 3/*adverse effects
Obesity/*etiology
Protein Isoforms/*metabolism
Animals ; Female ; Glucose Intolerance/physiopathology ; Humans ; Male ; Mice ; Mice, Knockout ; Obesity/physiopathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Alpha adaptins show isoform-specific association with neurofibrillary tangles in Alzheimer's disease.
Autorzy:
Srinivasan S; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, USA.
Gal J; Spinal Cord and Brain Injury Research Center (SCoBIRC), University of Kentucky, Lexington, Kentucky, USA.; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, USA.
Bachstetter A; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, USA.; Spinal Cord and Brain Injury Research Center (SCoBIRC), University of Kentucky, Lexington, Kentucky, USA.; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, USA.
Nelson PT; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, USA.; Department of Pathology, University of Kentucky, Lexington, Kentucky, USA.
Pokaż więcej
Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2022 Feb; Vol. 48 (2), pp. e12776. Date of Electronic Publication: 2021 Dec 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Adaptor Protein Complex alpha Subunits/*metabolism
Alzheimer Disease/*metabolism
Brain/*metabolism
Neurofibrillary Tangles/*metabolism
Protein Isoforms/*metabolism
Aged ; Aged, 80 and over ; Alzheimer Disease/pathology ; Brain/pathology ; Female ; Humans ; Male ; Middle Aged ; Neurofibrillary Tangles/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An analysis of tissue-specific alternative splicing at the protein level.
Autorzy:
Rodriguez JM; Cardiovascular Proteomics Laboratory, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Calle Melchor Fernandez, Madrid, Spain.
Pozo F; Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Calle Melchor Fernandez, Madrid, Spain.
di Domenico T; Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Calle Melchor Fernandez, Madrid, Spain.
Vazquez J; Cardiovascular Proteomics Laboratory, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Calle Melchor Fernandez, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
Tress ML; Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Calle Melchor Fernandez, Madrid, Spain.
Pokaż więcej
Źródło:
PLoS computational biology [PLoS Comput Biol] 2020 Oct 05; Vol. 16 (10), pp. e1008287. Date of Electronic Publication: 2020 Oct 05 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Isoforms*/chemistry
Protein Isoforms*/classification
Protein Isoforms*/genetics
Alternative Splicing/*genetics
Organ Specificity/*genetics
Animals ; Computational Biology ; Genome/genetics ; Humans ; Proteomics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.
Autorzy:
Newton S; Mammalian Genetics Unit, MRC Harwell Institute, Harwell Oxford, United Kingdom.
Kong F; School of Sciences, University of Sheffield, Sheffield, United Kingdom.
Carlton AJ; School of Sciences, University of Sheffield, Sheffield, United Kingdom.
Aguilar C; Mammalian Genetics Unit, MRC Harwell Institute, Harwell Oxford, United Kingdom.
Parker A; Mammalian Genetics Unit, MRC Harwell Institute, Harwell Oxford, United Kingdom.
Codner GF; Mary Lyon Centre, MRC Harwell Institute, Harwell Oxford, United Kingdom.
Teboul L; Mary Lyon Centre, MRC Harwell Institute, Harwell Oxford, United Kingdom.
Wells S; Mary Lyon Centre, MRC Harwell Institute, Harwell Oxford, United Kingdom.
Brown SDM; Mammalian Genetics Unit, MRC Harwell Institute, Harwell Oxford, United Kingdom.
Marcotti W; School of Sciences, University of Sheffield, Sheffield, United Kingdom.; Sheffield Neuroscience Institute, University of Sheffield, Sheffield, United Kingdom.
Bowl MR; Mammalian Genetics Unit, MRC Harwell Institute, Harwell Oxford, United Kingdom.; UCL Ear Institute, University College London, London, United Kingdom.
Pokaż więcej
Źródło:
PLoS genetics [PLoS Genet] 2022 Jan 31; Vol. 18 (1), pp. e1009937. Date of Electronic Publication: 2022 Jan 31 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherins/*genetics
Hair Cells, Auditory, Inner/*physiology
Hearing/*genetics
Membrane Glycoproteins/*genetics
Protein Isoforms/*genetics
Animals ; Loss of Function Mutation ; Mice ; Mice, Knockout ; Plasma Membrane Calcium-Transporting ATPases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dual isoform sequencing reveals complex transcriptomic and epitranscriptomic landscapes of a prototype baculovirus.
Autorzy:
Torma G; Department of Medical Biology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, 6720, Hungary.
Tombácz D; Department of Medical Biology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, 6720, Hungary.
Moldován N; Department of Medical Biology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, 6720, Hungary.
Fülöp Á; Department of Medical Biology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, 6720, Hungary.
Prazsák I; Department of Medical Biology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, 6720, Hungary.
Csabai Z; Department of Medical Biology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, 6720, Hungary.
Snyder M; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Boldogkői Z; Department of Medical Biology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, 6720, Hungary. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Jan 25; Vol. 12 (1), pp. 1291. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Baculoviridae/*genetics
High-Throughput Nucleotide Sequencing/*methods
Protein Isoforms/*genetics
Sequence Analysis, RNA/*methods
Transcriptome/*genetics
Methylation ; Nucleopolyhedroviruses/genetics ; Open Reading Frames ; RNA, Viral ; TATA Box ; Untranslated Regions
SCR Organism:
Autographa californica multiple nuclear polyhedrosis virus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Ecdysone receptor isoforms play distinct roles in larval-pupal-adult transition in Leptinotarsa decemlineata.
Autorzy:
Xu QY; Education Ministry Key Laboratory of Integrated Management of Crop Diseases and Pests, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Deng P; Education Ministry Key Laboratory of Integrated Management of Crop Diseases and Pests, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Zhang Q; Education Ministry Key Laboratory of Integrated Management of Crop Diseases and Pests, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Li A; Education Ministry Key Laboratory of Integrated Management of Crop Diseases and Pests, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Fu KY; Institute of Plant Protection, Xinjiang Academy of Agricultural Sciences, Urumqi, China.
Guo WC; Institute of Microbiological Application, Xinjiang Academy of Agricultural Science, Urumqi, China.
Li GQ; Education Ministry Key Laboratory of Integrated Management of Crop Diseases and Pests, College of Plant Protection, Nanjing Agricultural University, Nanjing, China.
Pokaż więcej
Źródło:
Insect science [Insect Sci] 2020 Jun; Vol. 27 (3), pp. 487-499. Date of Electronic Publication: 2019 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Ecdysterone/*metabolism
Metamorphosis, Biological/*genetics
Metamorphosis, Biological/*physiology
Protein Isoforms/*metabolism
Receptors, Steroid/*genetics
Animals ; Coleoptera/embryology ; Insect Proteins/genetics ; Insect Proteins/metabolism ; Larva/metabolism ; Molting/genetics ; Protein Isoforms/genetics ; Pupa/metabolism ; RNA Interference ; Receptors, Steroid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reciprocal Homer1a and Homer2 Isoform Expression Is a Key Mechanism for Muscle Soleus Atrophy in Spaceflown Mice.
Autorzy:
Blottner D; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Institute of Integrative Neuroanatomy, 10117 Berlin, Germany.; Neuromuscular System and Neuromuscular Signaling, Center of Space Medicine Berlin, 10115 Berlin, Germany.
Trautmann G; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Institute of Integrative Neuroanatomy, 10117 Berlin, Germany.
Furlan S; C.N.R. Institute of Neuroscience, 35121 Padova, Italy.
Gambara G; Neuromuscular System and Neuromuscular Signaling, Center of Space Medicine Berlin, 10115 Berlin, Germany.
Block K; Neuromuscular System and Neuromuscular Signaling, Center of Space Medicine Berlin, 10115 Berlin, Germany.
Gutsmann M; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Institute of Integrative Neuroanatomy, 10117 Berlin, Germany.
Sun LW; Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.
Worley PF; Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21205, USA.
Gorza L; Department of Biomedical Sciences, University of Padova, 35131 Padova, Italy.
Scano M; Department of Biomedical Sciences, University of Padova, 35131 Padova, Italy.
Lorenzon P; Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.; B.R.A.I.N., Centre for Neuroscience, 34127 Trieste, Italy.
Vida I; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Institute of Integrative Neuroanatomy, 10117 Berlin, Germany.
Volpe P; Department of Biomedical Sciences, University of Padova, 35131 Padova, Italy.
Salanova M; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Institute of Integrative Neuroanatomy, 10117 Berlin, Germany.; Neuromuscular System and Neuromuscular Signaling, Center of Space Medicine Berlin, 10115 Berlin, Germany.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 22; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 22.
Typ publikacji:
Journal Article
MeSH Terms:
Homer Scaffolding Proteins/*metabolism
Muscle Proteins/*metabolism
Muscle, Skeletal/*metabolism
Muscular Atrophy/*metabolism
Protein Isoforms/*metabolism
Animals ; Hindlimb Suspension/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Neuromuscular Junction/metabolism ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar ; Space Flight/methods ; Weightlessness
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Natural History of a Mouse Model Overexpressing the Dp71 Dystrophin Isoform.
Autorzy:
Lim KRQ; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Shah MNA; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Woo S; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Wilton-Clark H; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Zhabyeyev P; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada.
Wang F; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada.
Maruyama R; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Oudit GY; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada.; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB T6G 2B7, Canada.
Yokota T; Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.; Muscular Dystrophy Canada Research Chair, Edmonton, AB T6G 2H7, Canada.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 23; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Dystrophin/*genetics
Muscular Dystrophy, Duchenne/*metabolism
Protein Isoforms/*metabolism
Animals ; Disease Models, Animal ; Dystrophin/metabolism ; Humans ; Mice ; Muscle, Skeletal/metabolism ; Muscular Dystrophy, Duchenne/genetics ; Myocardium/metabolism ; Promoter Regions, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Spontaneous pulmonary emphysema in mice lacking all three nitric oxide synthase isoforms.
Autorzy:
Kato K; Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Tsutsui M; Department of Pharmacology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan. .
Noguchi S; Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Iha Y; Department of Pharmacology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
Naito K; Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Ogoshi T; Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Nishida C; Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Tahara M; Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Yamashita H; Department of Pharmacology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
Wang KY; Shared-Use Research Center, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Toyohira Y; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Yanagihara N; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Masuzaki H; Second Department of Internal Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Shimokawa H; Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tanimoto A; Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Yatera K; Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Nov 11; Vol. 11 (1), pp. 22088. Date of Electronic Publication: 2021 Nov 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nitric Oxide Synthase/*genetics
Protein Isoforms/*genetics
Pulmonary Emphysema/*genetics
Animals ; Disease Models, Animal ; Down-Regulation/genetics ; Gene Expression/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; RNA, Messenger/genetics ; Signal Transduction/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Assessment of ICAM-1 N-glycoforms in mouse and human models of endothelial dysfunction.
Autorzy:
Regal-McDonald K; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Somarathna M; Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Lee T; Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Litovsky SH; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Barnes J; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Peretik JM; Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America.
Traylor JG Jr; Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America.
Orr AW; Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America.
Patel RP; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2020 Mar 24; Vol. 15 (3), pp. e0230358. Date of Electronic Publication: 2020 Mar 24 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Atherosclerosis/*pathology
Endothelium, Vascular/*pathology
Inflammation/*pathology
Intercellular Adhesion Molecule-1/*immunology
Protein Isoforms/*analysis
Adult ; Aged ; Animals ; Arteries/cytology ; Arteries/pathology ; Arteriovenous Shunt, Surgical/adverse effects ; Atherosclerosis/immunology ; Disease Models, Animal ; Endothelium, Vascular/cytology ; Endothelium, Vascular/immunology ; Epitopes/analysis ; Epitopes/immunology ; Epitopes/metabolism ; Female ; Glycosylation ; Human Umbilical Vein Endothelial Cells ; Humans ; Inflammation/immunology ; Intercellular Adhesion Molecule-1/analysis ; Intercellular Adhesion Molecule-1/metabolism ; Macrophages/immunology ; Male ; Mannose/metabolism ; Mice ; Mice, Knockout, ApoE ; Middle Aged ; N-Acetylneuraminic Acid/metabolism ; Protein Isoforms/metabolism ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Amino Acids 563-566 of the Na Exchanger Isoform 1 C-Terminal Cytosolic Tail Prevent Protein Degradation and Stabilize Protein Expression and Activity.
Autorzy:
Li X; Department of Biochemistry, University Alberta, Edmonton, AB T6G 2H7, Canada.
Dutta D; Department of Biochemistry, University Alberta, Edmonton, AB T6G 2H7, Canada.; Department of Biotechnology, Thapar Institute of Engineering and Technology Patiala, Patiala 147004, Punjab, India.
Jung M; Medical Biochemistry and Molecular Biology, Saarland University, 66421 Homburg, Germany.
Zimmermann R; Medical Biochemistry and Molecular Biology, Saarland University, 66421 Homburg, Germany.
Fliegel L; Department of Biochemistry, University Alberta, Edmonton, AB T6G 2H7, Canada.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Mar 03; Vol. 21 (5). Date of Electronic Publication: 2020 Mar 03.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Isoforms/*metabolism
Sodium-Hydrogen Exchanger 1/*metabolism
Electrophoresis, Polyacrylamide Gel ; Humans ; Hydrogen-Ion Concentration ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Plasmids/genetics ; Protein Isoforms/genetics ; Protein Stability ; Proteolysis ; Sodium-Hydrogen Exchanger 1/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Isoform-resolved correlation analysis between mRNA abundance regulation and protein level degradation.
Autorzy:
Salovska B; Yale Cancer Biology Institute, Yale University, West Haven, CT, USA.; Department of Genome Integrity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Zhu H; Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Gandhi T; Biognosys, Zurich-Schlieren, Switzerland.
Frank M; European Molecular Biology Laboratory, Heidelberg, Germany.
Li W; Yale Cancer Biology Institute, Yale University, West Haven, CT, USA.
Rosenberger G; Department of Systems Biology, Columbia University, New York, NY, USA.
Wu C; Yale Cancer Biology Institute, Yale University, West Haven, CT, USA.
Germain PL; Institute for Neuroscience, D-HEST, ETH Zurich, Zurich, Switzerland.; Statistical Bioinformatics Lab, DMLS, University of Zürich, Zurich, Switzerland.
Zhou H; Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Hodny Z; Department of Genome Integrity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Reiter L; Biognosys, Zurich-Schlieren, Switzerland.
Liu Y; Yale Cancer Biology Institute, Yale University, West Haven, CT, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
Pokaż więcej
Źródło:
Molecular systems biology [Mol Syst Biol] 2020 Mar; Vol. 16 (3), pp. e9170.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Isoforms/*analysis
Proteins/*analysis
RNA Isoforms/*metabolism
RNA, Messenger/*metabolism
Alternative Splicing ; Gene Expression Regulation, Neoplastic ; HeLa Cells ; Humans ; Isotope Labeling/methods ; Mass Spectrometry ; Protein Isoforms/metabolism ; Proteins/metabolism ; Proteolysis ; Proteomics/methods ; RNA Isoforms/genetics ; RNA, Messenger/genetics ; Workflow
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The effects of insecticides on two splice variants of the glutamate-gated chloride channel receptor of the major malaria vector, Anopheles gambiae.
Autorzy:
Atif M; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
Lynch JW; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
Keramidas A; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
Pokaż więcej
Źródło:
British journal of pharmacology [Br J Pharmacol] 2020 Jan; Vol. 177 (1), pp. 175-187. Date of Electronic Publication: 2019 Oct 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anopheles/*genetics
Chloride Channels/*genetics
Insecticides/*pharmacology
Mosquito Vectors/*genetics
Protein Isoforms/*genetics
Amino Acid Sequence ; Animals ; Anopheles/metabolism ; Chloride Channels/metabolism ; Dose-Response Relationship, Drug ; Female ; Glutamic Acid/pharmacology ; Ivermectin/pharmacology ; Mosquito Vectors/metabolism ; Oocytes/drug effects ; Oocytes/metabolism ; Protein Isoforms/metabolism ; Xenopus laevis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Human Isoform of RNA Polymerase II Subunit hRPB11bα Specifically Interacts with Transcription Factor ATF4.
Autorzy:
Proshkin SA; Laboratory of Mechanisms of Gene Expression, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Engelhardt Institute of Molecular Biology, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, 119991 Moscow, Russia.
Shematorova EK; Laboratory of Mechanisms of Gene Expression, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Shpakovski GV; Laboratory of Mechanisms of Gene Expression, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Dec 24; Vol. 21 (1). Date of Electronic Publication: 2019 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
Activating Transcription Factor 4/*metabolism
Protein Isoforms/*metabolism
RNA Polymerase II/*metabolism
Activating Transcription Factor 4/genetics ; Humans ; Protein Binding ; Protein Isoforms/genetics ; RNA Polymerase II/genetics ; Two-Hybrid System Techniques
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Influence of Quadruplex Structure in Proximity to P53 Target Sequences on the Transactivation Potential of P53 Alpha Isoforms.
Autorzy:
Porubiaková O; Faculty of Chemistry, Brno University of Technology, Purkyňova 118, 61200 Brno, Czech Republic.; Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 61265 Brno, Czech Republic.
Bohálová N; Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 61265 Brno, Czech Republic.; Department of Experimental Biology, Faculty of Science, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Inga A; Laboratory of Transcriptional Networks, Department CIBIO, University of Trento, via Sommarive 9, 38123 Trento, Italy.
Vadovičová N; Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 61265 Brno, Czech Republic.; Department of Biology, Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Coufal J; Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 61265 Brno, Czech Republic.
Fojta M; Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 61265 Brno, Czech Republic.
Brázda V; Faculty of Chemistry, Brno University of Technology, Purkyňova 118, 61200 Brno, Czech Republic.; Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 61265 Brno, Czech Republic.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Dec 24; Vol. 21 (1). Date of Electronic Publication: 2019 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
G-Quadruplexes*
Protein Isoforms/*metabolism
Tumor Suppressor Protein p53/*metabolism
Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Humans ; Promoter Regions, Genetic/genetics ; Protein Binding ; Protein Isoforms/genetics ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Response Elements/genetics ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Isoform-specific NF1 mRNA levels correlate with disease severity in Neurofibromatosis type 1.
Autorzy:
Assunto A; Department of Translational Medical Science, Section of Pediatrics, Federico II University, Via Sergio Pansini, 5, 80131, Naples, Italy.
Ferrara U; Department of Translational Medical Science, Section of Pediatrics, Federico II University, Via Sergio Pansini, 5, 80131, Naples, Italy.
De Luca A; IRCCS Casa Sollievo della Sofferenza, Molecular Genetics Unit, San Giovanni Rotondo, Foggia, Italy.
Pivonello C; Dipartimento di Medicina Clinica ed Endocrinologia, Università degli Studi di Napoli, 'Federico II', Naples, Italy.
Lombardo L; Department of Translational Medical Science, Section of Pediatrics, Federico II University, Via Sergio Pansini, 5, 80131, Naples, Italy.
Piscitelli A; Department of Translational Medical Science, Section of Pediatrics, Federico II University, Via Sergio Pansini, 5, 80131, Naples, Italy.
Tortora C; Department of Molecular Medicine and Medical Biotechnology Federico II University, Naples, Italy.
Pinna V; Department of Translational Medical Science, Section of Pediatrics, Federico II University, Via Sergio Pansini, 5, 80131, Naples, Italy.
Daniele P; Department of Translational Medical Science, Section of Pediatrics, Federico II University, Via Sergio Pansini, 5, 80131, Naples, Italy.
Pivonello R; Dipartimento di Medicina Clinica ed Endocrinologia, Università degli Studi di Napoli, 'Federico II', Naples, Italy.
Russo MG; Università della Campania 'Luigi Vanvitelli', AORN Colli, Ospedale Monaldi, Naples, Italy.
Limongelli G; Università della Campania 'Luigi Vanvitelli', AORN Colli, Ospedale Monaldi, Naples, Italy.
Colao A; Dipartimento di Medicina Clinica ed Endocrinologia, Università degli Studi di Napoli, 'Federico II', Naples, Italy.
Tartaglia M; Genetics and Rare Diseases Research Division, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Strisciuglio P; Department of Translational Medical Science, Section of Pediatrics, Federico II University, Via Sergio Pansini, 5, 80131, Naples, Italy.
Melis D; Department of Translational Medical Science, Section of Pediatrics, Federico II University, Via Sergio Pansini, 5, 80131, Naples, Italy. .
Pokaż więcej
Źródło:
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2019 Nov 15; Vol. 14 (1), pp. 261. Date of Electronic Publication: 2019 Nov 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neurofibromatosis 1/*metabolism
Neurofibromatosis 1/*pathology
Neurofibromin 1/*metabolism
Protein Isoforms/*metabolism
RNA, Messenger/*metabolism
Adolescent ; Adult ; Case-Control Studies ; Cerebrovascular Disorders/genetics ; Cerebrovascular Disorders/metabolism ; Cerebrovascular Disorders/pathology ; Child ; Child, Preschool ; Cognitive Dysfunction/genetics ; Cognitive Dysfunction/metabolism ; Cognitive Dysfunction/pathology ; Female ; Humans ; Infant ; Male ; Middle Aged ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Neurofibromatosis 1/genetics ; Neurofibromin 1/genetics ; Optic Nerve Glioma/genetics ; Optic Nerve Glioma/metabolism ; Optic Nerve Glioma/pathology ; Protein Biosynthesis ; Protein Isoforms/genetics ; RNA, Messenger/genetics ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 2236

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies