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Wyszukujesz frazę ""Protein Kinase Inhibitors/pharmacology"" wg kryterium: Temat


Tytuł :
MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance
Index Terms :
Antineoplastic Agents/pharmacology
Cell Line, Tumor
Cell Proliferation/drug effects
Colorectal Neoplasms/drug therapy
Drug Resistance, Neoplasm/drug effects
ErbB Receptors/antagonists & inhibitors
Gefitinib/pharmacology
Genes, APC
Humans
Intestinal Mucosa/drug effects
Mutation
Neoplastic Stem Cells/drug effects
Protein Kinase Inhibitors/pharmacology
Proto-Oncogene Proteins c-met/antagonists & inhibitors
Pyrazines/pharmacology
Signal Transduction
Triazines/pharmacology
Article
Źródło :
Gastroenterology vol.157 (2019) nr.4 p.1153-1155.e1 [ISSN 0016-5085]
URL :
https://pure.knaw.nl/portal/en/publications/met-signaling-overcomes-epidermal-growth-factor-receptor-inhibition-in-normal-and-colorectal-cancer-stem-cells-causing-drug-resistance(09dac440-1221-4d76-826c-d3f17ce4e1b4).html">https://pure.knaw.nl/portal/en/publications/met-signaling-overcomes-epidermal-growth-factor-receptor-inhibition-in-normal-and-colorectal-cancer-stem-cells-causing-drug-resistance(09dac440-1221-4d76-826c-d3f17ce4e1b4).html
Zasób elektroniczny
Tytuł :
MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance
Index Terms :
Antineoplastic Agents/pharmacology
Cell Line, Tumor
Cell Proliferation/drug effects
Colorectal Neoplasms/drug therapy
Drug Resistance, Neoplasm/drug effects
ErbB Receptors/antagonists & inhibitors
Gefitinib/pharmacology
Genes, APC
Humans
Intestinal Mucosa/drug effects
Mutation
Neoplastic Stem Cells/drug effects
Protein Kinase Inhibitors/pharmacology
Proto-Oncogene Proteins c-met/antagonists & inhibitors
Pyrazines/pharmacology
Signal Transduction
Triazines/pharmacology
Article
Źródło :
Gastroenterology vol.157 (2019) nr.4 p.1153-1155.e1 [ISSN 0016-5085]
URL :
https://pure.knaw.nl/portal/en/publications/met-signaling-overcomes-epidermal-growth-factor-receptor-inhibition-in-normal-and-colorectal-cancer-stem-cells-causing-drug-resistance(09dac440-1221-4d76-826c-d3f17ce4e1b4).html">https://pure.knaw.nl/portal/en/publications/met-signaling-overcomes-epidermal-growth-factor-receptor-inhibition-in-normal-and-colorectal-cancer-stem-cells-causing-drug-resistance(09dac440-1221-4d76-826c-d3f17ce4e1b4).html
Zasób elektroniczny
Tytuł :
CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to Palbociclib
Index Terms :
Sciences biomédicales en général
Antineoplastic Agents -- pharmacology
Breast Neoplasms -- pathology
Cell Cycle -- drug effects
Cell Line, Tumor
Cyclin-Dependent Kinase 4 -- antagonists & inhibitors -- chemistry
Female
Humans
Microarray Analysis
Phosphorylation
Piperazines -- pharmacology
Protein Kinase Inhibitors -- pharmacology
Protein Processing, Post-Translational
Pyridines -- pharmacology
Transcriptome
breast cancer / CDK4/6 inhibitors / cyclin-dependent kinase 4 / PD0332991 / sensitivity biomarker
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/251169">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/251169
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Tytuł :
Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase
Index Terms :
Animals
Aurora Kinase B
Aurora Kinases
Blastocyst/metabolism
Chromatin Assembly and Disassembly/drug effects
Chromosome Segregation
Fibroblasts/metabolism
Fluorescence Recovery After Photobleaching
HeLa Cells
Histones/immunology/*metabolism
Humans
Immunoglobulin Fab Fragments
Interphase/drug effects
Mice
Microscopy, Confocal
Phosphorylation
Protein Kinase Inhibitors/pharmacology
Protein Phosphatase 1/antagonists & inhibitors/metabolism
Protein Processing, Post-Translational/drug effects
Protein-Serine-Threonine Kinases/antagonists & inhibitors/metabolism
Serine
Time Factors
Journal Article
Tytuły dodatkowe :
Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase
URL :
http://jairo.nii.ac.jp/0083/00248151">http://jairo.nii.ac.jp/0083/00248151
10.1083/jcb.200904137
Zasób elektroniczny
Tytuł :
Accumulating microglia phagocytose injured neurons in hippocampal slice cultures: involvement of p38 MAP kinase
Index Terms :
Animals
Cell Movement/drug effects
Cell Proliferation/drug effects
Female
Fluorescence
Hippocampus/*pathology
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Microglia/drug effects/metabolism/*pathology
N-Methylaspartate/pharmacology
Nerve Tissue Proteins/metabolism
Neurons/drug effects/*enzymology/*pathology
Nuclear Proteins/metabolism
Phagocytosis/drug effects
Propidium/metabolism
Protein Kinase Inhibitors/pharmacology
Pyramidal Cells/drug effects/metabolism/pathology
Time Factors
Time-Lapse Imaging
Tissue Culture Techniques
p38 Mitogen-Activated Protein Kinases/*metabolism
Journal Article
Tytuły dodatkowe :
Accumulating microglia phagocytose injured neurons in hippocampal slice cultures: involvement of p38 MAP kinase
URL :
http://jairo.nii.ac.jp/0083/00238723">http://jairo.nii.ac.jp/0083/00238723
10.1371/journal.pone.0040813
Zasób elektroniczny
Tytuł :
CK2 phosphorylation of C/EBPdelta regulates its transcription factor activity.
Index Terms :
Amino Acid Sequence
CCAAT-Enhancer-Binding Protein-delta/genetics/metabolism
Casein Kinase II/antagonists & inhibitors/genetics/metabolism
Catalytic Domain
Conserved Sequence
HCT116 Cells
Humans
Molecular Sequence Data
Phosphorylation
Protein Interaction Domains and Motifs
Protein Kinase Inhibitors/pharmacology
Transcriptome
Protein kinase CK2
Protein-protein interaction
Transcription
Transcription factor
info:eu-repo/semantics/article
URL :
http://orbilu.uni.lu/handle/10993/27434">http://orbilu.uni.lu/handle/10993/27434
http://orbilu.uni.lu/bitstream/10993/27434/1/CK2%20phosphorylation.pdf">http://orbilu.uni.lu/bitstream/10993/27434/1/CK2%20phosphorylation.pdf
Zasób elektroniczny
Tytuł :
CK2 phosphorylation of C/EBPdelta regulates its transcription factor activity.
Index Terms :
Amino Acid Sequence
CCAAT-Enhancer-Binding Protein-delta/genetics/metabolism
Casein Kinase II/antagonists & inhibitors/genetics/metabolism
Catalytic Domain
Conserved Sequence
HCT116 Cells
Humans
Molecular Sequence Data
Phosphorylation
Protein Interaction Domains and Motifs
Protein Kinase Inhibitors/pharmacology
Transcriptome
Protein kinase CK2
Protein-protein interaction
Transcription
Transcription factor
info:eu-repo/semantics/article
URL :
http://orbilu.uni.lu/handle/10993/27434">http://orbilu.uni.lu/handle/10993/27434
http://orbilu.uni.lu/bitstream/10993/27434/1/CK2%20phosphorylation.pdf">http://orbilu.uni.lu/bitstream/10993/27434/1/CK2%20phosphorylation.pdf
Zasób elektroniczny
Tytuł :
CK2 phosphorylation of C/EBPdelta regulates its transcription factor activity.
Index Terms :
Amino Acid Sequence
CCAAT-Enhancer-Binding Protein-delta/genetics/metabolism
Casein Kinase II/antagonists & inhibitors/genetics/metabolism
Catalytic Domain
Conserved Sequence
HCT116 Cells
Humans
Molecular Sequence Data
Phosphorylation
Protein Interaction Domains and Motifs
Protein Kinase Inhibitors/pharmacology
Transcriptome
Protein kinase CK2
Protein-protein interaction
Transcription
Transcription factor
info:eu-repo/semantics/article
URL :
http://orbilu.uni.lu/handle/10993/27434">http://orbilu.uni.lu/handle/10993/27434
http://orbilu.uni.lu/bitstream/10993/27434/1/CK2%20phosphorylation.pdf">http://orbilu.uni.lu/bitstream/10993/27434/1/CK2%20phosphorylation.pdf
Zasób elektroniczny
Tytuł :
Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: application to the development of a new class of CK2 inhibitors.
Index Terms :
Casein Kinase II/antagonists & inhibitors
Casein Kinase II/metabolism
Catalysis
Dose-Response Relationship, Drug
Gold/chemistry
Humans
Indoles/chemical synthesis
Indoles/chemistry
Indoles/pharmacology
Molecular Structure
Protein Kinase Inhibitors/chemical synthesis
Protein Kinase Inhibitors/chemistry
Protein Kinase Inhibitors/pharmacology
Pyrazoles/chemical synthesis
Pyrazoles/chemistry
Pyrazoles/pharmacology
Structure-Activity Relationship
Journal Article
URL :
http://hdl.handle.net/2433/189820">http://hdl.handle.net/2433/189820
10.1039/c3ob40223a
Zasób elektroniczny
Tytuł :
Interaction between cAMP, volume-regulated anion channels and the Na +-HCO3--cotransporter, NBCe1, in the regulation of nutrient- and hypotonicity-induced insulin release from isolated rat pancreatic islets and tumoral insulin-producing BRIN-BD11 cells
Index Terms :
Cancérologie
Biologie moléculaire
Biochimie
Biologie
Animals
Anions
Cell Line, Tumor
Cyclic AMP -- analogs & derivatives -- metabolism
Estriol -- analogs & derivatives -- pharmacology
Food
Glucose -- pharmacology
Hypotonic Solutions -- pharmacology
Indoles -- pharmacology
Insulin -- biosynthesis -- secretion
Ion Channels -- metabolism
Islets of Langerhans -- drug effects -- secretion
Isotonic Solutions -- pharmacology
Mitogen-Activated Protein Kinases -- antagonists & inhibitors -- metabolism
Nitrobenzoates -- pharmacology
Phosphodiesterase Inhibitors -- pharmacology
Protein Kinase Inhibitors -- pharmacology
Rats
Reference Standards
Sodium -- metabolism
Sodium-Bicarbonate Symporters -- metabolism
Adenosine 3',5'-cyclic monophosphate
BRIN-BD11 cells
Insulin release
Na+-HCO3- cotransporter NBCe1
Rat isolated pancreatic islets
Volume-regulated anion channels
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/168864">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/168864
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Tytuł :
Design and synthesis of a novel class of CK2 inhibitors: application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles.
Index Terms :
Casein Kinase II/antagonists & inhibitors
Catalysis
Cell Line, Tumor
Cell Proliferation/drug effects
Copper/chemistry
Gold/chemistry
Heterocyclic Compounds/chemistry
Heterocyclic Compounds/pharmacology
Humans
Models, Molecular
Molecular Structure
Nitrogen Compounds/chemistry
Nitrogen Compounds/pharmacology
Protein Kinase Inhibitors/chemical synthesis
Protein Kinase Inhibitors/pharmacology
Structure-Activity Relationship
Journal Article
Źródło :
Organic & biomolecular chemistry
URL :
http://hdl.handle.net/2433/174130">http://hdl.handle.net/2433/174130
10.1039/c2ob25298h
Zasób elektroniczny
Tytuł :
Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: a breakthrough in the management of luminal (ER+/HER2-) breast cancers?
Index Terms :
Sciences biomédicales
Cancérologie
Antineoplastic Agents -- pharmacology -- therapeutic use
Breast Neoplasms -- drug therapy -- genetics -- metabolism
Clinical Trials as Topic
Drug Resistance, Neoplasm
Female
Humans
Phosphatidylinositol 3-Kinases -- antagonists & inhibitors -- genetics -- metabolism
Protein Kinase Inhibitors -- pharmacology -- therapeutic use
Receptor, erbB-2 -- metabolism
Receptors, Estrogen -- metabolism
Signal Transduction -- drug effects
Sirolimus -- pharmacology -- therapeutic use
TOR Serine-Threonine Kinases -- antagonists & inhibitors -- metabolism
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/148656">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/148656
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny

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