Skocz do pozycji: 1.

Tytuł:

The effects of restraint stress on ceramide metabolism disorders in the rat liver: the role of CerS6 in hepatocyte injury.

Autorzy:

Liu Y; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.; Department of Forensic Medicine, College of Medicine, Nantong University, Nantong, 226000, China.
Sun Z; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Sun Q; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Wang L; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Wang C; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Li Y; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Ma C; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Shi W; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Zhang G; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.; Hebei Province Laboratory of Experimental Animal, Shijiazhuang, 050017, China.
Dong Y; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China.
Zhang X; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China. .
Cong B; Department of Forensic Medicine, Hebei Medical University, No. 361 Zhong Shan Rd, Shijiazhuang, 050017, Hebei, China. .; Hainan Tropical Forensic Medicine Academician Workstation, Haikou, 571199, China. .

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Źródło:

Lipids in health and disease [Lipids Health Dis] 2024 Mar 02; Vol. 23 (1), pp. 68. Date of Electronic Publication: 2024 Mar 02.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*/metabolism
Tandem Mass Spectrometry*
Rats ; Animals ; Chromatography, Liquid ; Ceramides/metabolism ; Hepatocytes/metabolism ; Liver/metabolism ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism ; Apoptosis ; Sphingosine N-Acyltransferase/genetics ; Sphingosine N-Acyltransferase/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 2.

Tytuł:

The Role of the Dysregulated JNK Signaling Pathway in the Pathogenesis of Human Diseases and Its Potential Therapeutic Strategies: A Comprehensive Review.

Autorzy:

Yan H; Department of Ultrasound, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
He L; Department of Ultrasound, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Lv; Department of Endocrinology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Yang J; Cancer Center and State Key Laboratory of Biotherapy, Department of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.
Yuan Z; Cancer Center and State Key Laboratory of Biotherapy, Department of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.

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Źródło:

Biomolecules [Biomolecules] 2024 Feb 19; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 19.

Typ publikacji:

Journal Article; Review

MeSH Terms:

MAP Kinase Signaling System*
Mitogen-Activated Protein Kinases*/metabolism
Humans ; JNK Mitogen-Activated Protein Kinases/metabolism ; Cell Differentiation

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 3.

Tytuł:

Sesamin attenuates UVA-induced keratinocyte injury via inhibiting ASK-1-JNK/p38 MAPK pathways.

Autorzy:

Li H; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Zhu L; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Weng Z; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Fu H; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Liu J; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Mao Q; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Li W; The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Ding B; College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Cao Y; The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.

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Źródło:

Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Jan; Vol. 23 (1), pp. 316-325. Date of Electronic Publication: 2023 Aug 06.

Typ publikacji:

Journal Article

MeSH Terms:

p38 Mitogen-Activated Protein Kinases*/metabolism
p38 Mitogen-Activated Protein Kinases*/pharmacology
Matrix Metalloproteinase 9*/metabolism
Humans ; Reactive Oxygen Species/metabolism ; bcl-2-Associated X Protein/metabolism ; bcl-2-Associated X Protein/pharmacology ; Matrix Metalloproteinase 1/metabolism ; Keratinocytes/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-2/pharmacology ; JNK Mitogen-Activated Protein Kinases/metabolism ; JNK Mitogen-Activated Protein Kinases/pharmacology ; Apoptosis ; Superoxide Dismutase/metabolism ; Ultraviolet Rays/adverse effects

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 4.

Tytuł:

Dual-Specificity Phosphatases in Regulation of Tumor-Associated Macrophage Activity.

Autorzy:

Patysheva MR; Laboratory of Translational Cellular and Molecular Biomedicine, National Research Tomsk State University, 634050 Tomsk, Russia.; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634009 Tomsk, Russia.
Prostakishina EA; Laboratory of Translational Cellular and Molecular Biomedicine, National Research Tomsk State University, 634050 Tomsk, Russia.; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634009 Tomsk, Russia.
Budnitskaya AA; Laboratory of Translational Cellular and Molecular Biomedicine, National Research Tomsk State University, 634050 Tomsk, Russia.; Laboratory of Genetic Technologies, Siberian State Medical University, 634050 Tomsk, Russia.
Bragina OD; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634009 Tomsk, Russia.
Kzhyshkowska JG; Laboratory of Translational Cellular and Molecular Biomedicine, National Research Tomsk State University, 634050 Tomsk, Russia.; Laboratory of Genetic Technologies, Siberian State Medical University, 634050 Tomsk, Russia.; Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Mannheim Institute of Innate Immunosciences (MI3), University of Heidelberg, 68167 Mannheim, Germany.; German Red Cross Blood Service Baden-Württemberg-Hessen, 69117 Mannheim, Germany.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Dec 16; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 16.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Dual-Specificity Phosphatases*/metabolism
Mitogen-Activated Protein Kinases*/metabolism
Phosphoprotein Phosphatases/metabolism ; Tumor-Associated Macrophages/metabolism ; Protein Tyrosine Phosphatases/metabolism ; Mitogens ; Phosphorylation ; Protein Kinases/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism ; Dual Specificity Phosphatase 1/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 5.

Tytuł:

Photoprotective Effects of Epigallocatechin Gallate on Ultraviolet-Induced Zebrafish and Human Skin Fibroblasts Cells.

Autorzy:

Zhang J; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Xu Y; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Ruan X; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Zhang T; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Zi M; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.
Zhang Q; Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China.

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Źródło:

Mediators of inflammation [Mediators Inflamm] 2024 Jan 24; Vol. 2024, pp. 7887678. Date of Electronic Publication: 2024 Jan 24 (Print Publication: 2024).

Typ publikacji:

Journal Article

MeSH Terms:

Zebrafish*
Mitogen-Activated Protein Kinases*/metabolism
Catechin/*analogs & derivatives
Animals ; Humans ; NF-kappa B/metabolism ; Interleukin-6/metabolism ; Transcription Factor AP-1/metabolism ; Ultraviolet Rays/adverse effects ; Tumor Necrosis Factor-alpha/metabolism ; Skin/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism ; Fibroblasts/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism ; Reactive Oxygen Species/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 6.

Tytuł:

Resveratrol improves the prognosis of rats after spinal cord injury by inhibiting mitogen-activated protein kinases signaling pathway.

Autorzy:

Kan S; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Liu C; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Zhao X; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Feng S; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Zhu H; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Ma B; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Zhou M; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Fu X; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Hu W; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China.
Zhu R; Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, 300121, China. .

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Źródło:

Scientific reports [Sci Rep] 2023 Nov 13; Vol. 13 (1), pp. 19723. Date of Electronic Publication: 2023 Nov 13.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Mitogen-Activated Protein Kinases*/metabolism
Spinal Cord Injuries*
Rats ; Animals ; Rats, Sprague-Dawley ; Resveratrol/pharmacology ; Resveratrol/therapeutic use ; Tumor Necrosis Factor-alpha/pharmacology ; Interleukin-6/pharmacology ; Signal Transduction ; p38 Mitogen-Activated Protein Kinases/metabolism ; Prognosis ; Anti-Inflammatory Agents/pharmacology ; Spinal Cord/metabolism ; Recovery of Function

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 7.

Tytuł:

Mitogen-Activated Protein Kinase and Exploratory Nuclear Receptor Crosstalk in Cancer Immunotherapy.

Autorzy:

Burgermeister E; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Sep 26; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 26.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Mitogen-Activated Protein Kinases*/metabolism
Neoplasms*/therapy
Humans ; p38 Mitogen-Activated Protein Kinases ; JNK Mitogen-Activated Protein Kinases ; Receptors, Cytoplasmic and Nuclear ; Immunotherapy

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 8.

Tytuł:

Oral Intake of Inosine 5'-Monophosphate in Mice Promotes the Absorption of Exogenous Fatty Acids and Their Conversion into Triglycerides though Enhancing the Phosphorylation of Adenosine 5'-Monophosphate-Activated Protein Kinase in the Liver, Leading to Lipohyperplasia.

Autorzy:

Zhang B; Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Malianwa North Road No. 151, Haidian District, Beijing 100193, China.
Xu Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Malianwa North Road No. 151, Haidian District, Beijing 100193, China.
Liu J; Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Malianwa North Road No. 151, Haidian District, Beijing 100193, China.
Wu C; Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Malianwa North Road No. 151, Haidian District, Beijing 100193, China.
Zhao X; Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Malianwa North Road No. 151, Haidian District, Beijing 100193, China.
Zhou L; Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Malianwa North Road No. 151, Haidian District, Beijing 100193, China.
Xie Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Malianwa North Road No. 151, Haidian District, Beijing 100193, China.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Sep 26; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 26.

Typ publikacji:

Journal Article

MeSH Terms:

Protein Kinases*/metabolism
Fatty Acids*/metabolism
Mice ; Animals ; Triglycerides/metabolism ; Phosphorylation ; Acetyl-CoA Carboxylase/metabolism ; Acetyl Coenzyme A/metabolism ; Mice, Inbred C57BL ; Liver/metabolism ; Obesity/metabolism ; Adenosine/metabolism ; Inosine/metabolism ; AMP-Activated Protein Kinases/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 9.

Tytuł:

Repeated Rounds of Gonadotropin Stimulation Induce Imbalance in the Antioxidant Machinery and Activation of Pro-Survival Proteins in Mouse Oviducts.

Autorzy:

Di Nisio V; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, SE-14186 Stockholm, Sweden.; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, SE-14186 Stockholm, Sweden.
Antonouli S; Department of Clinical Chemistry, Faculty of Medicine, University of Ioannina, PC-45110 Ioannina, Greece.
Colafarina S; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Zarivi O; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Rossi G; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Cecconi S; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Poma AMG; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 May 26; Vol. 24 (11). Date of Electronic Publication: 2023 May 26.

Typ publikacji:

Journal Article

MeSH Terms:

Mitogen-Activated Protein Kinases*/metabolism
Antioxidants*
Mice ; Animals ; JNK Mitogen-Activated Protein Kinases ; HSP27 Heat-Shock Proteins ; p38 Mitogen-Activated Protein Kinases ; Apoptosis ; Mitogen-Activated Protein Kinase 8 ; DNA, Mitochondrial

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 10.

Tytuł:

Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells.

Autorzy:

Lynch KD; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Iverson DT; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Bachhav NK; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Call MR; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Yue GE; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Prasad B; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.
Clarke JD; Department of Pharmaceutical Sciences, Washington State University, Spokane, WA 99202, USA.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Jul 06; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 06.

Typ publikacji:

Journal Article

MeSH Terms:

Mitogen-Activated Protein Kinases*/metabolism
Chemical and Drug Induced Liver Injury*/metabolism
Humans ; Microcystins/toxicity ; Phosphorylation ; Phosphoprotein Phosphatases/metabolism ; Cytoskeleton/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 11.

Tytuł:

MKK4 Inhibitors-Recent Development Status and Therapeutic Potential.

Autorzy:

Katzengruber L; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmaceutical Sciences, Faculty of Sciences, University of Tuebingen, 72076 Tübingen, Germany.
Sander P; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmaceutical Sciences, Faculty of Sciences, University of Tuebingen, 72076 Tübingen, Germany.
Laufer S; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmaceutical Sciences, Faculty of Sciences, University of Tuebingen, 72076 Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided & Functionally Instructed Tumor Therapies', Eberhard Karls Universität Tübingen, 72076 Tübingen, Germany.; Tübingen Center for Academic Drug Discovery, Auf der Morgenstelle 8, 72076 Tübingen, Germany.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Apr 19; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 19.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Ovarian Neoplasms*/pathology
p38 Mitogen-Activated Protein Kinases*/metabolism
Female ; Humans ; Male ; JNK Mitogen-Activated Protein Kinases/metabolism ; MAP Kinase Kinase 4/metabolism ; Phosphorylation

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 12.

Tytuł:

FGF19 increases mitochondrial biogenesis and fusion in chondrocytes via the AMPKα-p38/MAPK pathway.

Autorzy:

Kan S; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Pi C; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Zhang L; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Guo D; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Niu Z; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Liu Y; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Duan M; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Pu X; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Bai M; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Zhou C; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Zhang D; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China.
Xie J; Lab of Bone and Joint Disease, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, Sichuan, China. .; National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610064, China. .

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Źródło:

Cell communication and signaling : CCS [Cell Commun Signal] 2023 Mar 13; Vol. 21 (1), pp. 55. Date of Electronic Publication: 2023 Mar 13.

Typ publikacji:

Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Transcription Factors*/metabolism
AMP-Activated Protein Kinases*/metabolism
Chondrocytes/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism ; Organelle Biogenesis ; Sirtuin 1/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 13.

Tytuł:

Comprehensive Data-Driven Assessment of Non-Kinase Targets of Inhibitors of the Human Kinome.

Autorzy:

Mobasher M; LIMES Program Unit Chemical Biology and Medicinal Chemistry, Department of Life Science Informatics and Data Science, B-IT, Lamarr Institute for Machine Learning and Artificial Intelligence, University of Bonn, Friedrich-Hirzebruch-Allee 5/6, 53115 Bonn, Germany.
Vogt M; LIMES Program Unit Chemical Biology and Medicinal Chemistry, Department of Life Science Informatics and Data Science, B-IT, Lamarr Institute for Machine Learning and Artificial Intelligence, University of Bonn, Friedrich-Hirzebruch-Allee 5/6, 53115 Bonn, Germany.
Xerxa E; LIMES Program Unit Chemical Biology and Medicinal Chemistry, Department of Life Science Informatics and Data Science, B-IT, Lamarr Institute for Machine Learning and Artificial Intelligence, University of Bonn, Friedrich-Hirzebruch-Allee 5/6, 53115 Bonn, Germany.
Bajorath J; LIMES Program Unit Chemical Biology and Medicinal Chemistry, Department of Life Science Informatics and Data Science, B-IT, Lamarr Institute for Machine Learning and Artificial Intelligence, University of Bonn, Friedrich-Hirzebruch-Allee 5/6, 53115 Bonn, Germany.

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Źródło:

Biomolecules [Biomolecules] 2024 Feb 21; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 21.

Typ publikacji:

Journal Article

MeSH Terms:

Protein Kinases*/metabolism
Signal Transduction*
Humans ; Phosphorylation ; Binding Sites ; Pharmaceutical Preparations ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 14.

Tytuł:

A resource database for protein kinase substrate sequence-preference motifs based on large-scale mass spectrometry data.

Autorzy:

Poll BG; Epithelial Systems Biology Laboratory, Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, National Institutes of Health, Bethesda, MD, 20892-1603, USA.
Leo KT; Epithelial Systems Biology Laboratory, Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, National Institutes of Health, Bethesda, MD, 20892-1603, USA.
Deshpande V; Epithelial Systems Biology Laboratory, Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, National Institutes of Health, Bethesda, MD, 20892-1603, USA.
Jayatissa N; Epithelial Systems Biology Laboratory, Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, National Institutes of Health, Bethesda, MD, 20892-1603, USA.
Pisitkun T; Epithelial Systems Biology Laboratory, Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, National Institutes of Health, Bethesda, MD, 20892-1603, USA.; Center of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Park E; Epithelial Systems Biology Laboratory, Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, National Institutes of Health, Bethesda, MD, 20892-1603, USA.
Yang CR; Epithelial Systems Biology Laboratory, Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, National Institutes of Health, Bethesda, MD, 20892-1603, USA.
Raghuram V; Epithelial Systems Biology Laboratory, Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, National Institutes of Health, Bethesda, MD, 20892-1603, USA.
Knepper MA; Epithelial Systems Biology Laboratory, Systems Biology Center, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, National Institutes of Health, Bethesda, MD, 20892-1603, USA. .

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Źródło:

Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 19; Vol. 22 (1), pp. 137. Date of Electronic Publication: 2024 Feb 19.

Typ publikacji:

Video-Audio Media; Journal Article; Research Support, N.I.H., Intramural

MeSH Terms:

Protein Kinases*/metabolism
Proteins*/metabolism
Animals ; Humans ; Phylogeny ; Phosphorylation ; Mass Spectrometry/methods ; Mammals/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 15.

Tytuł:

Hypothalamic AMP-Activated Protein Kinase as a Whole-Body Energy Sensor and Regulator.

Autorzy:

Min SH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Diabetes Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Song DK; Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Lee CH; Program of Material Science for Medicine and Pharmaceutics, Hallym University, Chuncheon, Korea.
Roh E; Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Korea.
Kim MS; Division of Endocrinology and Metabolism, Department of Internal Medicine, Diabetes Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

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Źródło:

Endocrinology and metabolism (Seoul, Korea) [Endocrinol Metab (Seoul)] 2024 Feb; Vol. 39 (1), pp. 1-11. Date of Electronic Publication: 2024 Feb 14.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*/metabolism
Diabetes Mellitus, Type 2*/metabolism
Humans ; Hypothalamus/metabolism ; Insulin/metabolism ; Glucose

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 16.

Tytuł:

In Silico Investigation of Parkin-Activating Mutations Using Simulations and Network Modeling.

Autorzy:

Islam NN; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Weber CA; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Coban M; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Cocker LT; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Fiesel FC; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Springer W; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Caulfield TR; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.; Department of Neurosurgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.; Department of Cancer Biology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.; Department of Biochemistry & Molecular Biology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.; Department of Computational Biology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

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Źródło:

Biomolecules [Biomolecules] 2024 Mar 19; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 19.

Typ publikacji:

Journal Article

MeSH Terms:

Protein Kinases*/metabolism
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
Humans ; Ubiquitin-Protein Ligases/metabolism ; Mutation

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 17.

Tytuł:

Development of Genetically Encoded Fluorescent KSR1-Based Probes to Track Ceramides during Phagocytosis.

Autorzy:

Girik V; Department of Pathology and Immunology, Geneva Center for Inflammation Research, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
van Ek L; Department of Cellular Physiology and Metabolism, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.; Diabetes Center, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Dentand Quadri I; Department of Pathology and Immunology, Geneva Center for Inflammation Research, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Azam M; Department of Pathology and Immunology, Geneva Center for Inflammation Research, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Cruz Cobo M; Department of Pathology and Immunology, Geneva Center for Inflammation Research, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Mandavit M; Department of Pathology and Immunology, Geneva Center for Inflammation Research, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Riezman I; Department of Biochemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, 1211 Geneva, Switzerland.
Riezman H; Department of Biochemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, 1211 Geneva, Switzerland.
Gavin AC; Department of Cellular Physiology and Metabolism, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.; Diabetes Center, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.; Department of Biochemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, 1211 Geneva, Switzerland.
Nunes-Hasler P; Department of Pathology and Immunology, Geneva Center for Inflammation Research, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Mar 05; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 05.

Typ publikacji:

Journal Article

MeSH Terms:

Ceramides*/metabolism
Fluorescent Dyes*
Protein Kinases*
Signal Transduction/physiology ; Phagocytosis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 18.

Tytuł:

AMPK stimulation inhibits YAP/TAZ signaling to ameliorate hepatic fibrosis.

Autorzy:

Shihan MH; Department of Medicine, University of California, San Francisco, San Francisco, CA, 94115, USA.
Sharma S; Department of Medicine, University of California, San Francisco, San Francisco, CA, 94115, USA.
Cable C; Department of Medicine, University of California, San Francisco, San Francisco, CA, 94115, USA.
Prathigudupu V; Department of Medicine, University of California, San Francisco, San Francisco, CA, 94115, USA.
Chen A; Department of Medicine, University of California, San Francisco, San Francisco, CA, 94115, USA.
Mattis AN; Department of Pathology, University of California, San Francisco, San Francisco, CA, 94143, USA.; The Liver Center, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.
Chen JY; Department of Medicine, University of California, San Francisco, San Francisco, CA, 94115, USA. .; The Liver Center, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA. .

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Źródło:

Scientific reports [Sci Rep] 2024 Mar 03; Vol. 14 (1), pp. 5205. Date of Electronic Publication: 2024 Mar 03.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*
Liver Cirrhosis*
Animals ; Mice ; Hippo Signaling Pathway ; Protein Serine-Threonine Kinases/genetics ; Signal Transduction

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 19.

Tytuł:

Parkin inhibits proliferation and migration of bladder cancer via ubiquitinating Catalase.

Autorzy:

Zhang R; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Jiang W; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Wang G; Department of Biological Repositories, Human Genetic Resources Preservation Center of Hubei Province, Hubei Key Laboratory of Urological Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhang Y; Euler Technology, ZGC Life Sciences Park, Beijing, China.; Center for Quantitative Biology, School of Life Sciences, Peking University, Beijing, China.
Liu W; Department of Urology, Peking University Aerospace Center Hospital, Beijing, China.
Li M; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yu J; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yan X; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhou F; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Du W; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Qian K; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Biological Repositories, Human Genetic Resources Preservation Center of Hubei Province, Hubei Key Laboratory of Urological Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xiao Y; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Biological Repositories, Human Genetic Resources Preservation Center of Hubei Province, Hubei Key Laboratory of Urological Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Liu T; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China. .
Ju L; Department of Biological Repositories, Human Genetic Resources Preservation Center of Hubei Province, Hubei Key Laboratory of Urological Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China. .
Wang X; Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China. .; Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China. .

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Źródło:

Communications biology [Commun Biol] 2024 Feb 29; Vol. 7 (1), pp. 245. Date of Electronic Publication: 2024 Feb 29.

Typ publikacji:

Journal Article

MeSH Terms:

Protein Kinases*/genetics
Urinary Bladder Neoplasms*/genetics
Humans ; Catalase/genetics ; Reactive Oxygen Species/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 20.

Tytuł:

Hygrothermal stress increases malignant arrhythmias susceptibility by inhibiting the LKB1-AMPK-Cx43 pathway.

Autorzy:

Chi J; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.; Department of Geriatric Cardiology, General Hospital of Southern Theater Command, Guangzhou, China.; Branch of National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Guangzhou, China.; Guangzhou Key Laboratory of Cardiac Rehabilitation, Guangzhou, China.
Wu N; Graduate School, Guangzhou University of Chinese Medicine, Guangzhou, China.
Li P; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.; Department of Geriatric Cardiology, General Hospital of Southern Theater Command, Guangzhou, China.
Hu J; Department of Geriatric Cardiology, General Hospital of Southern Theater Command, Guangzhou, China.; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Cai H; Department of Geriatric Cardiology, General Hospital of Southern Theater Command, Guangzhou, China.; Graduate School, Guangzhou University of Chinese Medicine, Guangzhou, China.
Lin C; Branch of National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Guangzhou, China.; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Lai Y; Branch of National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Guangzhou, China.; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Yang H; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.; Department of Geriatric Cardiology, General Hospital of Southern Theater Command, Guangzhou, China.
Huang J; Department of Geriatric Cardiology, General Hospital of Southern Theater Command, Guangzhou, China.; Branch of National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Guangzhou, China.
Li M; Department of Geriatric Cardiology, General Hospital of Southern Theater Command, Guangzhou, China.; Branch of National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Guangzhou, China.
Xu L; The First School of Clinical Medicine, Southern Medical University, Guangzhou, China. xxgnk_.; Department of Geriatric Cardiology, General Hospital of Southern Theater Command, Guangzhou, China. xxgnk_.; Branch of National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Guangzhou, China. xxgnk_.; Guangzhou Key Laboratory of Cardiac Rehabilitation, Guangzhou, China. xxgnk_.

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Źródło:

Scientific reports [Sci Rep] 2024 Feb 29; Vol. 14 (1), pp. 5010. Date of Electronic Publication: 2024 Feb 29.

Typ publikacji:

Journal Article

MeSH Terms:

Connexin 43*/metabolism
AMP-Activated Protein Kinases*/metabolism
Rats ; Animals ; Rats, Sprague-Dawley ; Arrhythmias, Cardiac ; Protein Serine-Threonine Kinases/metabolism ; Phosphorylation ; Adenosine Monophosphate/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 21.

Tytuł:

Cloflucarban Illuminates Specificity and Context-Dependent Activation of the PINK1-Parkin Pathway by Mitochondrial Complex Inhibition.

Autorzy:

Ramirez AT; Department of Biochemistry, Jennie Smoly Caruthers Biotechnology Building, University of Colorado-Boulder, 3415 Colorado Ave, Boulder, CO 80303, USA.
Liu Z; Department of Biochemistry, Jennie Smoly Caruthers Biotechnology Building, University of Colorado-Boulder, 3415 Colorado Ave, Boulder, CO 80303, USA.
Xu Q; Department of Biochemistry, Jennie Smoly Caruthers Biotechnology Building, University of Colorado-Boulder, 3415 Colorado Ave, Boulder, CO 80303, USA.
Nowosadtko S; Department of Biochemistry, Jennie Smoly Caruthers Biotechnology Building, University of Colorado-Boulder, 3415 Colorado Ave, Boulder, CO 80303, USA.
Liu X; Department of Biochemistry, Jennie Smoly Caruthers Biotechnology Building, University of Colorado-Boulder, 3415 Colorado Ave, Boulder, CO 80303, USA.

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Źródło:

Biomolecules [Biomolecules] 2024 Feb 20; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 20.

Typ publikacji:

Journal Article

MeSH Terms:

Protein Kinases*/metabolism
Ubiquitin-Protein Ligases*/metabolism
Carbanilides*
Humans ; Reproducibility of Results ; Mitochondria/metabolism ; Albumins/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 22.

Tytuł:

KINtaro: protein kinase-like database.

Autorzy:

Baranowski B; Laboratory of Plant Pathogenesis, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.
Krysińska M; Department of Biochemistry and Microbiology, Warsaw University of Life Sciences (SGGW), Warsaw, Poland.
Gradowski M; Department of Biochemistry and Microbiology, Warsaw University of Life Sciences (SGGW), Warsaw, Poland. marcin_.

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Źródło:

BMC research notes [BMC Res Notes] 2024 Feb 16; Vol. 17 (1), pp. 50. Date of Electronic Publication: 2024 Feb 16.

Typ publikacji:

Journal Article

MeSH Terms:

Protein Kinases*/genetics
Proteins*
Humans ; Phosphorylation ; Amino Acid Sequence ; Sequence Alignment ; Databases, Protein

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 23.

Tytuł:

The Protein Kinase A Inhibitor KT5720 Prevents Endothelial Dysfunctions Induced by High-Dose Irradiation.

Autorzy:

Boittin FX; Unité de Radiobiologie, Département Effets Biologiques des Rayonnements, IRBA-Institut de Recherche Biomédicale des Armées, Place du Général Valérie André, 91223 Brétigny-sur-Orge, France.
Guitard N; Unité de Radiobiologie, Département Effets Biologiques des Rayonnements, IRBA-Institut de Recherche Biomédicale des Armées, Place du Général Valérie André, 91223 Brétigny-sur-Orge, France.
Toth M; Université Paris-Saclay, INSERM, Laboratory of Signalling and Cardiovascular Pathophysiology U1180, 91400 Orsay, France.
Riccobono D; Unité de Radiobiologie, Département Effets Biologiques des Rayonnements, IRBA-Institut de Recherche Biomédicale des Armées, Place du Général Valérie André, 91223 Brétigny-sur-Orge, France.
Théry H; Unité de Radiobiologie, Département Effets Biologiques des Rayonnements, IRBA-Institut de Recherche Biomédicale des Armées, Place du Général Valérie André, 91223 Brétigny-sur-Orge, France.
Bobe R; Université Paris-Saclay, INSERM, Hémostase Inflammation Thrombose HITh U1176, 94276 Le Kremlin-Bicêtre, France.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.

Typ publikacji:

Journal Article

MeSH Terms:

Endothelial Cells*/metabolism
Cyclic AMP-Dependent Protein Kinases*/metabolism
Carbazoles*
Pyrroles*
Intracellular Signaling Peptides and Proteins*
Humans ; Cells, Cultured

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 24.

Tytuł:

Vagus nerve stimulation inhibits cortical spreading depression via glutamate-dependent TrkB activation mechanism in the nucleus tractus solitarius.

Autorzy:

Liu TT; Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chen SP; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Clinical Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Division of Translational Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.
Wang SJ; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yen JC; Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

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Źródło:

Cephalalgia : an international journal of headache [Cephalalgia] 2024 Feb; Vol. 44 (2), pp. 3331024241230466.

Typ publikacji:

Journal Article

MeSH Terms:

Cortical Spreading Depression*
Vagus Nerve Stimulation*
Protein Kinases*
Rats ; Animals ; Solitary Nucleus/physiology ; Glutamic Acid ; Vagus Nerve/physiology ; Receptors, Glutamate

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 25.

Tytuł:

Overexpression of salusin‑β downregulates adipoR1 expression to prevent fatty acid oxidation in HepG2 cells.

Autorzy:

Xu A; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei 430065, P.R. China.
Wang L; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei 430065, P.R. China.
Luo M; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei 430065, P.R. China.
Zhang H; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei 430065, P.R. China.
Ning M; Jiamusi College, Heilongjiang University of Chinese Medicine, Jiamusi, Heilongjiang 154007, P.R. China.
Pan J; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei 430065, P.R. China.
Duan X; Clinical Laboratory, Ezhou Central Hospital, Ezhou, Hubei 436000, P.R. China.
Wang Y; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei 430065, P.R. China.
Liu X; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, Hubei 430065, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2024 Feb; Vol. 29 (2). Date of Electronic Publication: 2023 Dec 08.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*/metabolism
Lipid Metabolism*
Receptors, Adiponectin*/genetics
Receptors, Adiponectin*/metabolism
Humans ; Fatty Acids, Nonesterified/metabolism ; Hep G2 Cells ; Liver/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 26.

Tytuł:

Dock10 Regulates Cardiac Function under Neurohormonal Stress.

Autorzy:

Segal L; Department of Physiology and Cell Biology, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.; Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Etzion S; Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Elyagon S; Department of Physiology and Cell Biology, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.; Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Shahar M; Department of Physiology and Cell Biology, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Klapper-Goldstein H; Department of Physiology and Cell Biology, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.; Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Levitas A; Pediatric Cardiology Department, Soroka University Medical Center, Beer-Sheva 8410501, Israel.
Kapiloff MS; Departments of Ophthalmology and Medicine (Cardiovascular Medicine), Stanford Cardiovascular Institute, Stanford University, Palo Alto 94304-1209, CA, USA.
Parvari R; The Shraga Segal Department of Microbiology, Immunology and Genetics, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.; National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Etzion Y; Department of Physiology and Cell Biology, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.; Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2022 Aug 25; Vol. 23 (17). Date of Electronic Publication: 2022 Aug 25.

Typ publikacji:

Journal Article

MeSH Terms:

Myocytes, Cardiac*/metabolism
p38 Mitogen-Activated Protein Kinases*/genetics
p38 Mitogen-Activated Protein Kinases*/metabolism
Guanine Nucleotide Exchange Factors/*metabolism
Angiotensin II/metabolism ; Angiotensin II/pharmacology ; Animals ; Cardiomegaly/metabolism ; JNK Mitogen-Activated Protein Kinases/metabolism ; Mice ; Myocardium/metabolism ; Signal Transduction

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 27.

Tytuł:

Potential and limitations of PKA/ PKG inhibitors for platelet studies.

Autorzy:

Shpakova V; Laboratory of cellular mechanisms of blood homeostasis, Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, Saint Petersburg, Russia.
Rukoyatkina N; Laboratory of cellular mechanisms of blood homeostasis, Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, Saint Petersburg, Russia.
Walter U; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz of the Johannes Gutenberg University Mainz, Mainz, Germany.
Gambaryan S; Laboratory of cellular mechanisms of blood homeostasis, Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, Saint Petersburg, Russia.

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Źródło:

Platelets [Platelets] 2022 Aug 18; Vol. 33 (6), pp. 859-868. Date of Electronic Publication: 2021 Nov 30.

Typ publikacji:

Journal Article

MeSH Terms:

Cyclic AMP*/metabolism
Cyclic GMP-Dependent Protein Kinases*/metabolism
Blood Platelets/metabolism ; Cyclic AMP-Dependent Protein Kinases ; Cyclic GMP/metabolism ; Cyclic GMP/pharmacology ; Humans ; Intracellular Signaling Peptides and Proteins

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 28.

Tytuł:

Bayesian analysis of dynamic phosphoproteomic data identifies protein kinases mediating GPCR responses.

Autorzy:

Leo KT; Epithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Chou CL; Epithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Yang CR; Epithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Park E; Epithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Raghuram V; Epithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Knepper MA; Epithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. .

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Źródło:

Cell communication and signaling : CCS [Cell Commun Signal] 2022 Jun 03; Vol. 20 (1), pp. 80. Date of Electronic Publication: 2022 Jun 03.

Typ publikacji:

Journal Article; Video-Audio Media; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

MeSH Terms:

Aquaporin 2*/genetics
Aquaporin 2*/metabolism
Protein Kinases*/metabolism
Animals ; Bayes Theorem ; Calcium/metabolism ; Calmodulin/metabolism ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Phosphorylation ; Rats ; Receptors, G-Protein-Coupled/metabolism ; Receptors, Vasopressin/metabolism ; Vasopressins/metabolism ; Water/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 29.

Tytuł:

AMP activated kinase negatively regulates hepatic Fetuin-A via p38 MAPK-C/EBPβ/E3 Ubiquitin Ligase Signaling pathway.

Autorzy:

Kothari V; Department of Nutrition and Dietetics, Boshell Diabetes and Metabolic Diseases Research Program, Auburn University, Auburn, AL, United States of America.
Babu JR; Department of Nutrition and Dietetics, Boshell Diabetes and Metabolic Diseases Research Program, Auburn University, Auburn, AL, United States of America.
Mathews ST; Department of Nutrition and Dietetics, Boshell Diabetes and Metabolic Diseases Research Program, Auburn University, Auburn, AL, United States of America.; Department of Nutrition and Dietetics, Samford University, Birmingham, AL, United States of America.

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Źródło:

PloS one [PLoS One] 2022 May 06; Vol. 17 (5), pp. e0266472. Date of Electronic Publication: 2022 May 06 (Print Publication: 2022).

Typ publikacji:

Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

MeSH Terms:

AMP-Activated Protein Kinases*/metabolism
MAP Kinase Signaling System*
Animals ; Glucose/metabolism ; Insulin/metabolism ; Liver/metabolism ; Phosphorylation ; Rats ; Signal Transduction ; Ubiquitin-Protein Ligases/metabolism ; alpha-2-HS-Glycoprotein/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 30.

Tytuł:

Dexamethasone Attenuates the Expression of MMP-13 in Chondrocytes through MKP-1.

Autorzy:

Lehtola T; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Nummenmaa E; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Tuure L; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Hämäläinen M; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Nieminen RM; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Moilanen T; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.; Coxa Hospital for Joint Replacement, 33520 Tampere, Finland.
Pemmari A; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.
Moilanen E; The Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 33014 Tampere, Finland.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2022 Mar 31; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 31.

Typ publikacji:

Journal Article

MeSH Terms:

Chondrocytes*/metabolism
p38 Mitogen-Activated Protein Kinases*/metabolism
Animals ; Cells, Cultured ; Dexamethasone/pharmacology ; JNK Mitogen-Activated Protein Kinases/metabolism ; Matrix Metalloproteinase 13/genetics ; Matrix Metalloproteinase 13/metabolism ; Mice ; Mitogen-Activated Protein Kinases/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 31.

Tytuł:

Metastasis and MAPK Pathways.

Autorzy:

Kciuk M; Doctoral School of Exact and Natural Sciences, University of Lodz, Banacha Street 12/16, 90-237 Lodz, Poland.; Department of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 12/16 Banacha St., 90-237 Lodz, Poland.
Gielecińska A; Department of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 12/16 Banacha St., 90-237 Lodz, Poland.
Budzinska A; Laboratory of Mitochondrial Biochemistry, Department of Bioenergetics, Faculty of Biology, Adam Mickiewicz University, 61-614 Poznan, Poland.
Mojzych M; Department of Chemistry, Siedlce University of Natural Sciences and Humanities, 3 Maja 54, 08-110 Siedlce, Poland.
Kontek R; Department of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 12/16 Banacha St., 90-237 Lodz, Poland.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2022 Mar 31; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 31.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Mitogen-Activated Protein Kinases*/metabolism
Neoplasms*
Humans ; JNK Mitogen-Activated Protein Kinases/metabolism ; MAP Kinase Signaling System ; Phosphorylation ; p38 Mitogen-Activated Protein Kinases/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 32.

Tytuł:

Convergent and divergent roles of the glucose-responsive kinase SNF4 in Candida tropicalis .

Autorzy:

Ke CL; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Lew SQ; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Hsieh Y; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Chang SC; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Lin CH; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.

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Źródło:

Virulence [Virulence] 2023 Dec; Vol. 14 (1), pp. 2175914.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

AMP-Activated Protein Kinases*/genetics
AMP-Activated Protein Kinases*/metabolism
Candida tropicalis*/genetics
Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/metabolism
Animals ; Glucose/metabolism ; Mammals ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Transcription Factors/genetics

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 33.

Tytuł:

The role of CSE1L silencing in the regulation of proliferation and apoptosis via the AMPK/mTOR signaling pathway in chronic myeloid leukemia.

Autorzy:

Liu XY; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Shanxi Medical University, Taiyuan, People's Republic of China.
Wang YH; Laboratory Department, The Second Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.
Wang J; Shanxi Medical University, Taiyuan, People's Republic of China.
Quan JK; Shanxi Medical University, Taiyuan, People's Republic of China.
Li XD; Shanxi Medical University, Taiyuan, People's Republic of China.
Guan KP; Laboratory Department, The Second Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.

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Źródło:

Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 1-9.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*/genetics
AMP-Activated Protein Kinases*/metabolism
AMP-Activated Protein Kinases*/pharmacology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/pathology
Humans ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Apoptosis ; Cell Proliferation ; K562 Cells

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 34.

Tytuł:

BNIP3 overexpression may promote myeloma cell apoptosis by enhancing sensitivity to bortezomib via the p38 MAPK pathway.

Autorzy:

Xiao P; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Chen X; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Dong Z; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Fan W; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Chen Y; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Su J; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Wang Q; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.
Ma L; Department of Hematology and Rheumatology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China.

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Źródło:

Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2231739.

Typ publikacji:

Journal Article

MeSH Terms:

p38 Mitogen-Activated Protein Kinases*/metabolism
p38 Mitogen-Activated Protein Kinases*/pharmacology
Multiple Myeloma*/drug therapy
Multiple Myeloma*/genetics
Humans ; Bortezomib/pharmacology ; Caspase 3/metabolism ; Caspase 3/pharmacology ; Reactive Oxygen Species/metabolism ; bcl-2-Associated X Protein/metabolism ; bcl-2-Associated X Protein/pharmacology ; Apoptosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-2/pharmacology ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Proto-Oncogene Proteins/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 35.

Tytuł:

AMPK activator-treated human cardiac spheres enhance maturation and enable pathological modeling.

Autorzy:

Li D; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Armand LC; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Sun F; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Hwang H; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Wolfson D; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.
Rampoldi A; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Liu R; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Forghani P; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Hu X; Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Yu WM; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Qu CK; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Jones DP; Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Wu R; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Cho HC; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.
Maxwell JT; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA.
Xu C; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA. .; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA. .

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Źródło:

Stem cell research & therapy [Stem Cell Res Ther] 2023 Nov 08; Vol. 14 (1), pp. 322. Date of Electronic Publication: 2023 Nov 08.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*/genetics
AMP-Activated Protein Kinases*/metabolism
Induced Pluripotent Stem Cells*/metabolism
Humans ; Cells, Cultured ; Proteomics ; Myocytes, Cardiac/metabolism ; Cell Differentiation/physiology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 36.

Tytuł:

Abnormal expression of PRKAG2-AS results in dysfunction of cardiomyocytes through regulating PRKAG2 transcription by interacting with PPARG.

Autorzy:

Song XW; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China. xiao_wei_.
Su T; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
Li B; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
Huang YJ; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
He WX; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
Jiang LL; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
Li CJ; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
Huang SQ; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
Li SH; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
Guo ZF; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
Wu H; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China. .
Zhang BL; Department of Cardiology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China. .

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Źródło:

Clinical epigenetics [Clin Epigenetics] 2023 Nov 07; Vol. 15 (1), pp. 178. Date of Electronic Publication: 2023 Nov 07.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

AMP-Activated Protein Kinases*/genetics
AMP-Activated Protein Kinases*/metabolism
Heart Failure*/genetics
Myocardial Ischemia*
PPAR gamma*/genetics
PPAR gamma*/metabolism
RNA, Long Noncoding*/genetics
Humans ; Apoptosis ; DNA Methylation ; Hypoxia ; In Situ Hybridization, Fluorescence ; Myocytes, Cardiac/metabolism ; Rosiglitazone/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 37.

Tytuł:

DEL-1: a promising treatment for AMD-associated ER stress in retinal pigment epithelial cells.

Autorzy:

Kwon C; GenesisEgo, Seoul, Republic of Korea.
Cho W; Department of Pharmacology, College of Medicine, Chung-Ang University, 221, Heuksuk-dong, Dongjak-gu, Seoul, 156-756, Republic of Korea.
Choi SW; Department of Pharmacology, College of Medicine, Chung-Ang University, 221, Heuksuk-dong, Dongjak-gu, Seoul, 156-756, Republic of Korea.
Oh H; Department of Pharmacology, College of Medicine, Chung-Ang University, 221, Heuksuk-dong, Dongjak-gu, Seoul, 156-756, Republic of Korea.
Abd El-Aty AM; Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.; Department of Medical Pharmacology, Medical Faculty, Ataturk University, 25240, Erzurum, Türkiye.
Gecili I; Department of Medical Pharmacology, Medical Faculty, Ataturk University, 25240, Erzurum, Türkiye.
Jeong JH; Department of Pharmacology, College of Medicine, Chung-Ang University, 221, Heuksuk-dong, Dongjak-gu, Seoul, 156-756, Republic of Korea.; Department of Global Innovative Drugs, Graduate School of Chung-Ang University, Seoul, Republic of Korea.
Jung TW; Department of Pharmacology, College of Medicine, Chung-Ang University, 221, Heuksuk-dong, Dongjak-gu, Seoul, 156-756, Republic of Korea. .

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Źródło:

Journal of translational medicine [J Transl Med] 2024 Jan 09; Vol. 22 (1), pp. 38. Date of Electronic Publication: 2024 Jan 09.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*
Macular Degeneration*/therapy
Humans ; Caspase 3 ; Tunicamycin/pharmacology ; Vascular Endothelial Growth Factor A ; Myokines ; Epithelial Cells ; Retinal Pigments

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 38.

Tytuł:

Cinnamyl Alcohol Attenuates Adipogenesis in 3T3-L1 Cells by Arresting the Cell Cycle.

Autorzy:

Choi YR; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun 55365, Republic of Korea.; Department of Food Science and Biotechnology, Ewha Womans University, Seoul 03760, Republic of Korea.
Kim YS; Department of Food Science and Biotechnology, Ewha Womans University, Seoul 03760, Republic of Korea.
Kim MJ; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun 55365, Republic of Korea.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2024 Jan 05; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 05.

Typ publikacji:

Journal Article

MeSH Terms:

Adipogenesis*
AMP-Activated Protein Kinases*
Propanols*
Mice ; Animals ; 3T3-L1 Cells ; Cell Cycle ; Cell Division

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 39.

Tytuł:

RIPK3 activation promotes DAXX-dependent neuronal necroptosis after intracerebral hemorrhage in mice.

Autorzy:

Bai Q; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.; Anhui Province Key Laboratory of Non-coding RNA Basic and Clinical Transformation, Wannan Medical College, Wuhu, Anhui, China.
Wang S; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.
Rao D; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.
Zhou Z; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.
Wang J; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.
Wang Q; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.
Qin Y; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.
Chu Z; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.
Zhao S; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.
Yu D; Department of Ophthalmology, Wuhu Eye Hospital, Wuhu, Anhui, China.
Xu Y; Department of Neurology, First Affiliated Hospital of Wannan Medical College, Yijishan Hospital, Wuhu, Anhui, China.; Anhui Province Key Laboratory of Non-coding RNA Basic and Clinical Transformation, Wannan Medical College, Wuhu, Anhui, China.

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Źródło:

CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Jan; Vol. 30 (1), pp. e14397. Date of Electronic Publication: 2023 Aug 08.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Necroptosis*
Protein Kinases*/metabolism
Animals ; Humans ; Mice ; Brain/metabolism ; Cerebral Hemorrhage ; Co-Repressor Proteins/metabolism ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Receptor-Interacting Protein Serine-Threonine Kinases/genetics ; Receptor-Interacting Protein Serine-Threonine Kinases/metabolism ; RNA, Small Interfering/genetics

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 40.

Tytuł:

Ghrelin improves endothelial function and reduces blood pressure in Ang II-induced hypertensive mice: Role of AMPK.

Autorzy:

Deng J; Department of Endocrinology, People's Hospital of Chongqing Liang Jiang New Area, Chongqing, China.
Hu Y; Department of Endocrinology, Songshan General Hospital, Chongqing, China.
Zhang Y; Department of Endocrinology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yu F; Department of Endocrinology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.

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Źródło:

Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2023 Dec 31; Vol. 45 (1), pp. 2208774.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*/metabolism
Hypertension*/chemically induced
Hypertension*/drug therapy
Hypertension*/metabolism
Mice ; Animals ; Blood Pressure ; Ghrelin/pharmacology ; Angiotensin II/pharmacology ; Oxidative Stress ; Endothelium, Vascular

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 41.

Tytuł:

A Potent PDK4 Inhibitor for Treatment of Heart Failure with Reduced Ejection Fraction.

Autorzy:

Aizawa K; Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University, Shimotsuke 329-0498, Japan.; Clinical Pharmacology Center, Jichi Medical University Hospital, Shimotsuke 329-0498, Japan.; Division of Translational Research, Clinical Research Center, Jichi Medical University Hospital, Shimotsuke 329-0498, Japan.
Ikeda A; Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo 108-8641, Japan.
Tomida S; Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University, Shimotsuke 329-0498, Japan.
Hino K; Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University, Shimotsuke 329-0498, Japan.
Sugita Y; Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo 108-8641, Japan.
Hirose T; Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo 108-8641, Japan.
Sunazuka T; Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo 108-8641, Japan.
Kido H; Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima 770-8503, Japan.
Yokoyama S; RIKEN Cluster for Science, Technology and Innovation Hub, Yokohama 230-0045, Japan.
Nagai R; Jichi Medical University, Shimotsuke 329-0498, Japan.

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Źródło:

Cells [Cells] 2023 Dec 30; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 30.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Heart Failure*/drug therapy
Protein Kinases*
Animals ; Mice ; Stroke Volume ; Ventricular Function, Left ; Heart ; Disease Models, Animal

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 42.

Tytuł:

Role of TGF-β and p38 MAPK in TSG-6 Expression in Adipose Tissue-Derived Stem Cells In Vitro and In Vivo.

Autorzy:

Kwon HY; Department of Surgery, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Yoon Y; Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Hong JE; Department of Biomedical Laboratory Science, College of Software and Digital Healthcare Convergence, Yonsei University Mirae Campus, Wonju 26493, Republic of Korea.
Rhee KJ; Department of Biomedical Laboratory Science, College of Software and Digital Healthcare Convergence, Yonsei University Mirae Campus, Wonju 26493, Republic of Korea.
Sohn JH; Department of Convergence Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Jung PY; Department of Surgery, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Kim MY; Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.; Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Baik SK; Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.; Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Ryu H; Department of Surgery, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.
Eom YW; Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju 26426, Republic of Korea.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Dec 29; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 29.

Typ publikacji:

Journal Article

MeSH Terms:

Transforming Growth Factor beta*
p38 Mitogen-Activated Protein Kinases*
Pyrazoles*
Thiosemicarbazones*
Mice ; Animals ; Mice, Inbred C57BL ; Lipopolysaccharides/pharmacology ; Stem Cells ; Adipose Tissue

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 43.

Tytuł:

Ubiquinol attenuates γ-radiation induced coronary and aortic changes via PDGF/p38 MAPK/ICAM-1 related pathway.

Autorzy:

El-Sabbagh WA; Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt.
Fadel NA; Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt. noha_.
El-Hazek RM; Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt.
Osman AH; Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Ramadan LA; Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt.; Pharmacology and Toxicology Department, Faculty of Pharmacy, Egyptian Russian University (ERU), Cairo, Egypt.

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Źródło:

Scientific reports [Sci Rep] 2023 Dec 27; Vol. 13 (1), pp. 22959. Date of Electronic Publication: 2023 Dec 27.

Typ publikacji:

Journal Article

MeSH Terms:

p38 Mitogen-Activated Protein Kinases*/metabolism
Mitogen-Activated Protein Kinase 14*
Rats ; Animals ; Male ; Matrix Metalloproteinase 9 ; Intercellular Adhesion Molecule-1/metabolism ; Platelet-Derived Growth Factor/pharmacology ; Endothelial Cells/metabolism ; Cell Adhesion Molecules

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 44.

Tytuł:

1,3-Dichloroadamantyl-Containing Ureas as Potential Triple Inhibitors of Soluble Epoxide Hydrolase, p38 MAPK and c-Raf.

Autorzy:

Gladkikh BP; Department of Technology of Organic and Petrochemical Synthesis, Volgograd State Technical University, Volgograd 400005, Russia.
Danilov DV; Department of Technology of Organic and Petrochemical Synthesis, Volgograd State Technical University, Volgograd 400005, Russia.
D'yachenko VS; Department of Technology of Organic and Petrochemical Synthesis, Volgograd State Technical University, Volgograd 400005, Russia.; Department of Chemistry, Technology and Equipment of Chemical Industry, Volzhsky Polytechnic Institute (Branch), Volgograd State Technical University (VSTU), Volzhsky 404121, Russia.
Butov GM; Department of Technology of Organic and Petrochemical Synthesis, Volgograd State Technical University, Volgograd 400005, Russia.; Department of Chemistry, Technology and Equipment of Chemical Industry, Volzhsky Polytechnic Institute (Branch), Volgograd State Technical University (VSTU), Volzhsky 404121, Russia.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Dec 26; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 26.

Typ publikacji:

Journal Article

MeSH Terms:

p38 Mitogen-Activated Protein Kinases*
Mitogen-Activated Protein Kinase 14*
Humans ; Epoxide Hydrolases ; Chlorine ; Ligands ; Halogens ; Chlorides

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 45.

Tytuł:

AMPK-HIF-1α signaling enhances glucose-derived de novo serine biosynthesis to promote glioblastoma growth.

Autorzy:

Yun HJ; Department of Health Sciences, The Graduate School of Dong-A University, Busan, 49315, Republic of Korea.
Li M; Zhejiang Provincial Key Laboratory of Pancreatic Disease, the First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.
Guo D; Zhejiang Provincial Key Laboratory of Pancreatic Disease, the First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.
Jeon SM; Department of Health Sciences, The Graduate School of Dong-A University, Busan, 49315, Republic of Korea.
Park SH; Department of Health Sciences, The Graduate School of Dong-A University, Busan, 49315, Republic of Korea.
Lim JS; Department of Health Sciences, The Graduate School of Dong-A University, Busan, 49315, Republic of Korea.
Lee SB; Department of Health Sciences, The Graduate School of Dong-A University, Busan, 49315, Republic of Korea.
Liu R; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, People's Republic of China.
Du L; Key Laboratory of Laboratory of Medicine, Ministry of Education of China, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People's Republic of China.
Kim SH; Department of Health Sciences, The Graduate School of Dong-A University, Busan, 49315, Republic of Korea.
Shin TH; Department of Biomedical Sciences, Dong-A University, Busan, 49315, Republic of Korea.
Eyun SI; Department of Life Science, Chung-Ang University, Seoul, 06974, Republic of Korea.
Park YY; Department of Life Science, Chung-Ang University, Seoul, 06974, Republic of Korea. .
Lu Z; Zhejiang Provincial Key Laboratory of Pancreatic Disease, the First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China. .; Cancer Center, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China. .
Lee JH; Department of Health Sciences, The Graduate School of Dong-A University, Busan, 49315, Republic of Korea. .; Department of Biomedical Sciences, Dong-A University, Busan, 49315, Republic of Korea. .

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Źródło:

Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Dec 15; Vol. 42 (1), pp. 340. Date of Electronic Publication: 2023 Dec 15.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*
Glioblastoma*/pathology
Humans ; Serine ; Glucose/metabolism ; Glycine ; RNA ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Cell Line, Tumor ; Tumor Microenvironment ; Phosphofructokinase-2

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 46.

Tytuł:

The role of AMPK in macrophage metabolism, function and polarisation.

Autorzy:

Cui Y; Department of Physiology, School of Basic Medical Science, Southwest Medical University, Luzhou, 646000, China.; Department of General Surgery, Dongguan Huangjiang Hospital, Dongguan, 523061, Guangdong, China.
Chen J; Department of Physiology, School of Basic Medical Science, Southwest Medical University, Luzhou, 646000, China.
Zhang Z; Department of General Surgery, Dongguan Huangjiang Hospital, Dongguan, 523061, Guangdong, China.
Shi H; Department of Orthopedics, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, 646000, China.
Sun W; Department of Bone Joint and Bone Oncology, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China. .; The Central Laboratory, Shenzhen Second People's Hospital, Shenzhen, 518035, Guangdong, China. .
Yi Q; Department of Physiology, School of Basic Medical Science, Southwest Medical University, Luzhou, 646000, China. .

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Źródło:

Journal of translational medicine [J Transl Med] 2023 Dec 08; Vol. 21 (1), pp. 892. Date of Electronic Publication: 2023 Dec 08.

Typ publikacji:

Journal Article; Review

MeSH Terms:

AMP-Activated Protein Kinases*/metabolism
Macrophages*/metabolism
Humans ; Inflammation/metabolism ; Anti-Inflammatory Agents/therapeutic use ; Homeostasis ; Energy Metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 47.

Tytuł:

Hexavalent-Chromium-Induced Disruption of Mitochondrial Dynamics and Apoptosis in the Liver via the AMPK-PGC-1α Pathway in Ducks.

Autorzy:

Wang C; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
Dai X; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
Xing C; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
Zhang C; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
Cao H; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
Guo X; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
Liu P; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
Yang F; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
Zhuang Y; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
Hu G; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Dec 08; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 08.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*
Ducks*
Animals ; bcl-2-Associated X Protein/metabolism ; Mitochondrial Dynamics ; Ecosystem ; Hydrogen Peroxide ; Liver/metabolism ; Apoptosis ; Chromium/toxicity ; Proto-Oncogene Proteins c-bcl-2/genetics ; Superoxide Dismutase

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 48.

Tytuł:

Ozone alleviates MSU-induced acute gout pain via upregulating AMPK/GAS6/MerTK/SOCS3 signaling pathway.

Autorzy:

Fan W; Department of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China.
Liu C; Department of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China.
Chen D; The Fourth Affiliated Hospital of Nantong University, Jiangsu, China.; Yancheng Ruikang Hospital, Jiangsu, 224000, China.
Xu C; Department of Anesthesiology and Pain, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, China.
Qi X; Department of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China.
Zhang A; Nanjing University of Chinese Medicine Institute of Literature in Chinese Medicine, Jiangsu, 224000, China.
Zhu X; Department of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China.
Liu Y; Department of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China.
Wang L; Department of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China.
Hao L; The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Jiangsu, 224005, China. .
Liu WT; Department of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China. .
Hu L; Department of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China. .

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Źródło:

Journal of translational medicine [J Transl Med] 2023 Dec 08; Vol. 21 (1), pp. 890. Date of Electronic Publication: 2023 Dec 08.

Typ publikacji:

Journal Article

MeSH Terms:

AMP-Activated Protein Kinases*/metabolism
Gout*/therapy
Ozone*/therapeutic use
Arthralgia*/therapy
Animals ; Humans ; Mice ; c-Mer Tyrosine Kinase/metabolism ; Inflammation/complications ; Inflammation/therapy ; Signal Transduction ; Suppressor of Cytokine Signaling 3 Protein/genetics ; Suppressor of Cytokine Signaling 3 Protein/metabolism ; Disease Models, Animal

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 49.

Tytuł:

MP Allosterically Activates AMPK to Enhance ABCA1 Stability by Retarding the Calpain-Mediated Degradation Pathway.

Autorzy:

Li H; State Key Laboratory for Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Xian Nong Tan Street 1, Xicheng District, Beijing 100050, China.
Wang M; State Key Laboratory for Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Xian Nong Tan Street 1, Xicheng District, Beijing 100050, China.
Qu K; State Key Laboratory for Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Xian Nong Tan Street 1, Xicheng District, Beijing 100050, China.
Xu R; State Key Laboratory for Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Xian Nong Tan Street 1, Xicheng District, Beijing 100050, China.
Zhu H; State Key Laboratory for Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Xian Nong Tan Street 1, Xicheng District, Beijing 100050, China.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2023 Dec 08; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 08.

Typ publikacji:

Journal Article

MeSH Terms:

Calpain*/metabolism
AMP-Activated Protein Kinases*/metabolism
Cholesterol/metabolism ; Macrophages/metabolism ; Proteolysis ; ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter 1/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 50.

Tytuł:

Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase.

Autorzy:

Hassan AHE; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
Oh YI; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Lee CH; Department of Fundamental Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Kim YJ; Department of Fundamental Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Cho SB; Department of Fundamental Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Alam MM; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
Park SE; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Life and Biomedical and Pharmaceutical Sciences, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
Chung KS; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
Lee KT; Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Life and Biomedical and Pharmaceutical Sciences, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
Lee YS; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.; Department of Fundamental Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.

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Źródło:

Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2217695.

Typ publikacji:

Journal Article

MeSH Terms:

p38 Mitogen-Activated Protein Kinases*
Antineoplastic Agents*/pharmacology
Male ; Female ; Humans ; Phosphorylation ; Lipids

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły