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Wyszukujesz frazę ""Protein Multimerization"" wg kryterium: Temat


Tytuł :
Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7.
Autorzy :
Pham NTH; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Université du Québec, Laval, Quebec, Canada.
Létourneau M; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Université du Québec, Laval, Quebec, Canada.
Fortier M; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Université du Québec, Laval, Quebec, Canada.
Bégin G; Département de Biochimie, de Microbiologie et de Bio-informatique and Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Quebec, Canada; PROTEO, the Québec Network for Research on Protein Function, Engineering, and Applications, Université Laval, Québec, Quebec, Canada.
Al-Abdul-Wahid MS; Nuclear Magnetic Resonance Centre, University of Guelph, Guelph, Ontario, Canada.
Pucci F; Computational Biology and Bioinformatics, Université Libre de Bruxelles, Brussels, Belgium.
Folch B; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Université du Québec, Laval, Quebec, Canada.
Rooman M; Computational Biology and Bioinformatics, Université Libre de Bruxelles, Brussels, Belgium.
Chatenet D; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Université du Québec, Laval, Quebec, Canada.
St-Pierre Y; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Université du Québec, Laval, Quebec, Canada.
Lagüe P; Département de Biochimie, de Microbiologie et de Bio-informatique and Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Quebec, Canada; PROTEO, the Québec Network for Research on Protein Function, Engineering, and Applications, Université Laval, Québec, Quebec, Canada.
Calmettes C; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Université du Québec, Laval, Quebec, Canada; PROTEO, the Québec Network for Research on Protein Function, Engineering, and Applications, Université Laval, Québec, Quebec, Canada.
Doucet N; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Université du Québec, Laval, Quebec, Canada; PROTEO, the Québec Network for Research on Protein Function, Engineering, and Applications, Université Laval, Québec, Quebec, Canada. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Nov; Vol. 297 (5), pp. 101308. Date of Electronic Publication: 2021 Oct 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*/genetics
Apoptosis*/immunology
Galectins*/chemistry
Galectins*/genetics
Galectins*/immunology
Immune Tolerance*
Protein Multimerization*/genetics
Protein Multimerization*/immunology
T-Lymphocytes/*immunology
Allosteric Regulation ; Humans ; Jurkat Cells
Czasopismo naukowe
Tytuł :
Nonequilibrium self-assembly of multiple stored targets in a dimer-based system.
Autorzy :
Ben-Ari A; Faculty of Engineering, School of Electrical Engineering, Tel Aviv University, Tel Aviv 6997801, Israel.
Ben-Ari L; Faculty of Engineering, School of Electrical Engineering, Tel Aviv University, Tel Aviv 6997801, Israel.
Bisker G; Faculty of Engineering, Department of Biomedical Engineering, Tel Aviv University, Tel Aviv 6997801, Israel.
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Źródło :
The Journal of chemical physics [J Chem Phys] 2021 Dec 21; Vol. 155 (23), pp. 234113.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Multimerization*
Microtubules/*chemistry
Tubulin/*chemistry
Monte Carlo Method ; Thermodynamics
Czasopismo naukowe
Tytuł :
Single-particle cryo-EM reveals conformational variability of the oligomeric VCC β-barrel pore in a lipid bilayer.
Autorzy :
Sengupta N; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Mondal AK; Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Punjab, India.
Mishra S; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Chattopadhyay K; Centre for Protein Science, Design and Engineering, Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Punjab, India.
Dutta S; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Dec 06; Vol. 220 (12). Date of Electronic Publication: 2021 Oct 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cryoelectron Microscopy*
Protein Multimerization*
Bacterial Proteins/*chemistry
Bacterial Proteins/*ultrastructure
Lipid Bilayers/*chemistry
Perforin/*chemistry
Perforin/*ultrastructure
Vibrio cholerae/*metabolism
Cell Membrane/metabolism ; Cell Membrane/ultrastructure ; Models, Molecular ; Perforin/metabolism ; Protein Structure, Secondary
Czasopismo naukowe
Tytuł :
Divergence in Dimerization and Activity of Primate APOBEC3C.
Autorzy :
Gaba A; Department of Biochemistry, Microbiology, and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Canada. Electronic address: https://twitter.com/optimist1023.
Hix MA; Department of Chemistry, University of North Texas, Denton, TX, USA. Electronic address: https://twitter.com/markahix.
Suhail S; Department of Biological Sciences, Center for Systems Biology, University of Texas at Dallas, Richardson, TX, USA. Electronic address: https://twitter.com/sakuraa_329.
Flath B; Department of Biochemistry, Microbiology, and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Boysan B; Department of Chemistry, University of North Texas, Denton, TX, USA.
Williams DR; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. Electronic address: https://twitter.com/dani_renee_.
Pelletier T; Department of Biochemistry, Microbiology, and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Emerman M; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. Electronic address: https://twitter.com/memerman.
Morcos F; Department of Biological Sciences, Center for Systems Biology, University of Texas at Dallas, Richardson, TX, USA; Department of Bioengineering, University of Texas at Dallas, Dallas, TX, USA. Electronic address: https://twitter.com/MorcosLab.
Cisneros GA; Department of Chemistry, University of North Texas, Denton, TX, USA. Electronic address: https://twitter.com/CisnerosRes.
Chelico L; Department of Biochemistry, Microbiology, and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Canada. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Dec 03; Vol. 433 (24), pp. 167306. Date of Electronic Publication: 2021 Oct 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Evolution, Molecular*
HIV-1*
Protein Multimerization*/genetics
Cytidine Deaminase/*chemistry
Cytidine Deaminase/*classification
HIV Infections/*virology
Amino Acid Sequence ; Amino Acid Substitution/genetics ; Animals ; Cytidine Deaminase/genetics ; HEK293 Cells ; Humans ; Macaca mulatta ; Mutation ; Phylogeny ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Biochemical and structural studies of two tetrameric nucleoside 2'-deoxyribosyltransferases from psychrophilic and mesophilic bacteria: Insights into cold-adaptation.
Autorzy :
Fernández-Lucas J; Applied Biotechnology Group, Universidad Europea de Madrid, Urbanización El Bosque, E-28670 Villaviciosa de Odón, Madrid, Spain; Grupo de Investigación en Ciencias Naturales y Exactas, GICNEX, Universidad de la Costa, CUC, Calle 58 # 55 66, Barranquilla, Colombia.
Acebrón I; Department of Crystallography and Structural Biology, Institute Rocasolano (CSIC), Serrano 119, 28006 Madrid, Spain.
Wu RY; Bioscience Division, Argonne National Laboratory, Argonne, IL 60439, USA.
Alfaro Y; Department of Biochemistry and Molecular Biology I, Faculty of Biology, Complutense University of Madrid, C/José Antonio Nováis 2, 28040 Madrid, Spain.
Acosta J; Applied Biotechnology Group, Universidad Europea de Madrid, Urbanización El Bosque, E-28670 Villaviciosa de Odón, Madrid, Spain.
Kaminski PA; Institut Pasteur, Unite ́Biologie des Bactéries Pathogènes à Gram-positif, CNRS URL3526, Paris, France.
Arroyo M; Department of Biochemistry and Molecular Biology I, Faculty of Biology, Complutense University of Madrid, C/José Antonio Nováis 2, 28040 Madrid, Spain.
Joachimiak A; Department of Crystallography and Structural Biology, Institute Rocasolano (CSIC), Serrano 119, 28006 Madrid, Spain; Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Argonne, IL 60439, USA; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60367, USA.
Nocek BP; Bioscience Division, Argonne National Laboratory, Argonne, IL 60439, USA.
De la Mata I; Department of Biochemistry and Molecular Biology I, Faculty of Biology, Complutense University of Madrid, C/José Antonio Nováis 2, 28040 Madrid, Spain.
Mancheño JM; Department of Crystallography and Structural Biology, Institute Rocasolano (CSIC), Serrano 119, 28006 Madrid, Spain. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Dec 01; Vol. 192, pp. 138-150. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Molecular*
Protein Conformation*
Protein Multimerization*
Bacterial Proteins/*chemistry
Pentosyltransferases/*chemistry
Adaptation, Physiological ; Bacterial Proteins/isolation & purification ; Catalytic Domain ; Chemical Phenomena ; Cold Temperature ; Disulfides ; Enzyme Activation ; Enzyme Stability ; Pentosyltransferases/isolation & purification ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Spectrum Analysis ; Thermodynamics
Czasopismo naukowe
Tytuł :
New findings on GFP-like protein application as fluorescent tags: Fibrillogenesis, oligomerization, and amorphous aggregation.
Autorzy :
Stepanenko OV; Laboratory of Structural Dynamics, Stability and Folding of Proteins, Institute of Cytology, Russian Academy of Sciences, St. Petersburg 194064, Russia.
Sulatsky MI; Laboratory of Cell Morphology, Institute of Cytology, Russian Academy of Sciences, St. Petersburg 194064, Russia.
Mikhailova EV; Laboratory of Structural Dynamics, Stability and Folding of Proteins, Institute of Cytology, Russian Academy of Sciences, St. Petersburg 194064, Russia.
Kuznetsova IM; Laboratory of Structural Dynamics, Stability and Folding of Proteins, Institute of Cytology, Russian Academy of Sciences, St. Petersburg 194064, Russia.
Turoverov KK; Laboratory of Structural Dynamics, Stability and Folding of Proteins, Institute of Cytology, Russian Academy of Sciences, St. Petersburg 194064, Russia. Electronic address: .
Stepanenko OV; Laboratory of Structural Dynamics, Stability and Folding of Proteins, Institute of Cytology, Russian Academy of Sciences, St. Petersburg 194064, Russia. Electronic address: .
Sulatskaya AI; Laboratory of Structural Dynamics, Stability and Folding of Proteins, Institute of Cytology, Russian Academy of Sciences, St. Petersburg 194064, Russia.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Dec 01; Vol. 192, pp. 1304-1310. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, Reporter*
Protein Aggregates*
Protein Multimerization*
Amyloid/*chemistry
Green Fluorescent Proteins/*chemistry
Recombinant Fusion Proteins/*chemistry
Amyloid/metabolism ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; HeLa Cells ; Humans ; Protein Aggregation, Pathological ; Protein Binding ; Protein Conformation ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
BthTX-II from Bothrops jararacussu venom has variants with different oligomeric assemblies: An example of snake venom phospholipases A 2 versatility.
Autorzy :
Borges RJ; Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, São Paulo 18618-689, Brazil; Crystallographic Methods, Institute of Molecular Biology of Barcelona - Spanish National Research Council (IBMB-CSIC), Barcelona 08028, Spain. Electronic address: .
Salvador GHM; Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, São Paulo 18618-689, Brazil.
Campanelli HB; Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, São Paulo 18618-689, Brazil.
Pimenta DC; Biochemistry and Biophysics Laboratory, Butantan Institute, São Paulo, São Paulo 05503-900, Brazil.
de Oliveira Neto M; Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, São Paulo 18618-689, Brazil.
Usón I; Crystallographic Methods, Institute of Molecular Biology of Barcelona - Spanish National Research Council (IBMB-CSIC), Barcelona 08028, Spain; ICREA, Institució Catalana de Recerca i Estudis Avançats, Pg. Lluís Companys 23, 08010 Barcelona, Spain.
Fontes MRM; Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, São Paulo 18618-689, Brazil. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Nov 30; Vol. 191, pp. 255-266. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Multimerization*
Crotalid Venoms/*chemistry
Group II Phospholipases A2/*chemistry
Binding Sites ; Calcium/metabolism ; Crotalid Venoms/metabolism ; Group II Phospholipases A2/metabolism ; Molecular Dynamics Simulation ; Protein Binding
Czasopismo naukowe
Tytuł :
Homodimeric and Heterodimeric Interactions among Vertebrate Basic Helix-Loop-Helix Transcription Factors.
Autorzy :
Torres-Machorro AL; Laboratorio de Biología Celular, Departamento de Investigación en Fibrosis Pulmonar, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosío Villegas', Tlalpan, Mexico City 14080, Mexico.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 28; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Dimerization*
Protein Multimerization*
Basic Helix-Loop-Helix Transcription Factors/*chemistry
Basic Helix-Loop-Helix Transcription Factors/*metabolism
Animals ; Basic Helix-Loop-Helix Transcription Factors/classification ; Humans ; Models, Chemical ; Protein Structure, Quaternary
Czasopismo naukowe
Tytuł :
NTCP Oligomerization Occurs Downstream of the NTCP-EGFR Interaction during Hepatitis B Virus Internalization.
Autorzy :
Fukano K; Department of Virology II, National Institute of Infectious Diseasesgrid.410795.e, Tokyo, Japan.; Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
Oshima M; Department of Virology II, National Institute of Infectious Diseasesgrid.410795.e, Tokyo, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda, Japan.
Tsukuda S; Department of Virology II, National Institute of Infectious Diseasesgrid.410795.e, Tokyo, Japan.; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Aizaki H; Department of Virology II, National Institute of Infectious Diseasesgrid.410795.e, Tokyo, Japan.
Ohki M; Drug Design Laboratory, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.
Park SY; Drug Design Laboratory, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.
Wakita T; Department of Virology II, National Institute of Infectious Diseasesgrid.410795.e, Tokyo, Japan.
Wakae K; Department of Virology II, National Institute of Infectious Diseasesgrid.410795.e, Tokyo, Japan.
Watashi K; Department of Virology II, National Institute of Infectious Diseasesgrid.410795.e, Tokyo, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda, Japan.; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseasesgrid.410795.e, Tokyo, Japan.; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.; MIRAI, JST, Saitama, Japan.
Muramatsu M; Department of Virology II, National Institute of Infectious Diseasesgrid.410795.e, Tokyo, Japan.
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Źródło :
Journal of virology [J Virol] 2021 Nov 23; Vol. 95 (24), pp. e0093821. Date of Electronic Publication: 2021 Oct 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Multimerization*
Hepatitis B virus/*physiology
Organic Anion Transporters, Sodium-Dependent/*metabolism
Receptors, Virus/*metabolism
Symporters/*metabolism
Virus Internalization/*drug effects
Biological Transport ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Hep G2 Cells ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Hepatocytes/virology ; Humans ; Organic Anion Transporters, Sodium-Dependent/genetics ; Symporters/genetics ; Troglitazone/pharmacology ; Virus Attachment/drug effects
Czasopismo naukowe
Tytuł :
Structural Characterization of the Cooperativity of Unfolding of a Heterodimeric Protein using Hydrogen Exchange-Mass Spectrometry.
Autorzy :
Bhattacharjee R; National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India; Indian Institute of Science Education and Research, Pune, India. Electronic address: https://twitter.com/Rupam_B01.
Udgaonkar JB; National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India; Indian Institute of Science Education and Research, Pune, India. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Nov 19; Vol. 433 (23), pp. 167268. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mass Spectrometry*/methods
Models, Molecular*
Protein Conformation*
Protein Folding*
Protein Multimerization*
Proteins/*chemistry
Czasopismo naukowe
Tytuł :
Quantification of EGFR-HER2 Heterodimers in HER2-Overexpressing Breast Cancer Cells Using Liquid-Phase Electron Microscopy.
Autorzy :
Peckys DB; Clinic of Operative Dentistry, Periodontology and Preventive Dentistry, University Hospital, Saarland University, 66421 Homburg, Germany.
Gaa D; INM-Leibniz Institute for New Materials, 66123 Saarbrücken, Germany.
de Jonge N; INM-Leibniz Institute for New Materials, 66123 Saarbrücken, Germany.; Department of Physics, Saarland University, 66123 Saarbrücken, Germany.
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Źródło :
Cells [Cells] 2021 Nov 19; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Microscopy, Electron*
Protein Multimerization*
Breast Neoplasms/*metabolism
Breast Neoplasms/*ultrastructure
Receptor, ErbB-2/*metabolism
Cell Line, Tumor ; Cell Membrane/metabolism ; Cell Surface Extensions/metabolism ; ErbB Receptors/metabolism ; Female ; Humans ; Models, Biological ; Quantum Dots
Czasopismo naukowe
Tytuł :
Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble.
Autorzy :
Mühlhofer M; Center for Protein Assemblies, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 8, 85747, Garching, Germany.
Peters C; Center for Protein Assemblies, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 8, 85747, Garching, Germany.
Kriehuber T; Center for Protein Assemblies, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 8, 85747, Garching, Germany.; Boehringer Ingelheim, Birkendorfer Str. 65, 88397, Biberach an der Riß, Germany.
Kreuzeder M; Center for Protein Assemblies, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 8, 85747, Garching, Germany.; Ludwig-Maximilians-Universität München, Biozentrum Großhaderner Str. 2, 82152, Planegg-Martinsried, Germany.
Kazman P; Center for Protein Assemblies, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 8, 85747, Garching, Germany.; Roche Diagnostics, Nonnenwald 2, 82377, Penzberg, Germany.
Rodina N; BNMRZ, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 2, 85747, Garching, Germany.; Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und Umwelt, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Reif B; BNMRZ, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 2, 85747, Garching, Germany.; Helmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und Umwelt, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Haslbeck M; Center for Protein Assemblies, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 8, 85747, Garching, Germany.
Weinkauf S; Center for Protein Assemblies, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 8, 85747, Garching, Germany.
Buchner J; Center for Protein Assemblies, Department of Chemistry, Technische Universität München, Ernst-Otto-Fischer Str. 8, 85747, Garching, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Nov 18; Vol. 12 (1), pp. 6697. Date of Electronic Publication: 2021 Nov 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Multimerization*
Heat-Shock Proteins/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Binding Sites/genetics ; Circular Dichroism ; Cryoelectron Microscopy ; Fluorescence Resonance Energy Transfer ; Heat-Shock Proteins/chemistry ; Heat-Shock Proteins/genetics ; Heat-Shock Response ; Models, Molecular ; Mutation ; Phosphorylation ; Protein Binding ; Protein Conformation ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/ultrastructure ; Tandem Mass Spectrometry ; Temperature
Czasopismo naukowe
Tytuł :
Functional Properties of Oligomeric and Monomeric Forms of Helicobacter pylori VacA Toxin.
Autorzy :
Caso GC; Department of Medicine, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
McClain MS; Department of Medicine, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Erwin AL; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Truelock MD; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Campbell AM; Department of Medicine, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Leasure CS; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Nagel M; Mass Spectrometry Research Center, Department of Biochemistry, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Schey KL; Mass Spectrometry Research Center, Department of Biochemistry, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Lacy DB; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.; Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA.
Ohi MD; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Cover TL; Department of Medicine, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.; Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA.
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Źródło :
Infection and immunity [Infect Immun] 2021 Nov 16; Vol. 89 (12), pp. e0034821. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Protein Conformation*
Protein Multimerization*
Bacterial Proteins/*chemistry
Bacterial Proteins/*metabolism
Bacterial Toxins/*chemistry
Bacterial Toxins/*metabolism
Bacterial Proteins/genetics ; Bacterial Toxins/genetics ; Protein Binding ; Protein Interaction Domains and Motifs ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Zinc Induced Aβ 16 Aggregation Modeled by Molecular Dynamics.
Autorzy :
Tolstova AP; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov St. 32, 119991 Moscow, Russia.
Makarov AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov St. 32, 119991 Moscow, Russia.
Adzhubei AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov St. 32, 119991 Moscow, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 10; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Dynamics Simulation*
Protein Aggregates*
Protein Multimerization*
Amyloid beta-Peptides/*chemistry
Peptide Fragments/*chemistry
Zinc/*chemistry
Humans
Czasopismo naukowe
Tytuł :
Amino acid residues at core protein dimer-dimer interface modulate multiple steps of hepatitis B virus replication and HBeAg biogenesis.
Autorzy :
Liu H; Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.; Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America.
Cheng J; Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America.
Viswanathan U; Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America.
Chang J; Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America.
Lu F; Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Guo JT; Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Nov 09; Vol. 17 (11), pp. e1010057. Date of Electronic Publication: 2021 Nov 09 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Protein Multimerization*
Virus Assembly*
Virus Replication*
Hepatitis B/*virology
Hepatitis B e Antigens/*metabolism
Hepatitis B virus/*physiology
Viral Core Proteins/*chemistry
DNA Replication ; DNA, Viral ; Hep G2 Cells ; Humans ; Nucleocapsid ; Viral Core Proteins/metabolism
Czasopismo naukowe
Tytuł :
Clioquinol Decreases Levels of Phosphorylated, Truncated, and Oligomerized Tau Protein.
Autorzy :
Lin G; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.; Department of Neurology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.
Zhu F; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.; Department of Neurology, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China.
Kanaan NM; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI 49503, USA.
Asano R; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Shirafuji N; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.; Department of Aging and Dementia (DAD), Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Sasaki H; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Yamaguchi T; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Enomoto S; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.; Department of Aging and Dementia (DAD), Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Endo Y; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Ueno A; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Ikawa M; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Hayashi K; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Yamamura O; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Yen SH; Department of Neuroscience, Mayo Clinic Jacksonville, Jacksonville, FL 32224, USA.
Nakamoto Y; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.
Hamano T; Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.; Department of Aging and Dementia (DAD), Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan.; Life Science Innovation Center, University of Fukui, Fukui 910-1193, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 08; Vol. 22 (21). Date of Electronic Publication: 2021 Nov 08.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Multimerization*
Alzheimer Disease/*drug therapy
Clioquinol/*pharmacology
Gene Expression Regulation/*drug effects
Neurofibrillary Tangles/*drug effects
tau Proteins/*chemistry
tau Proteins/*metabolism
Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Autophagy ; Cell Line, Tumor ; Copper/chemistry ; Humans ; Neurofibrillary Tangles/metabolism ; Phosphorylation ; Protein Phosphatase 2/metabolism
Czasopismo naukowe
Tytuł :
The protein hydration layer in high glucose concentration: Dynamical responses in folded and intrinsically disordered dimeric states.
Autorzy :
Ghosh B; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, 741 246, India.
Sengupta N; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, 741 246, India. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Nov 05; Vol. 577, pp. 124-129. Date of Electronic Publication: 2021 Sep 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Dynamics Simulation*
Protein Folding*
Protein Multimerization*
Glucose/*chemistry
Intrinsically Disordered Proteins/*chemistry
Proteins/*chemistry
Amyloid beta-Peptides/chemistry ; Amyloid beta-Peptides/metabolism ; Glucose/metabolism ; Hydrophobic and Hydrophilic Interactions ; Intrinsically Disordered Proteins/metabolism ; Protein Conformation ; Proteins/metabolism ; Ubiquitin/chemistry ; Ubiquitin/metabolism ; Water/chemistry
Czasopismo naukowe
Tytuł :
Assembly of infectious Kaposi's sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer.
Autorzy :
Naniima P; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research (DZIF), partner sites Hannover-Braunschweig and Hamburg-Lübeck-Borstel-Riems, Braunschweig, Germany.
Naimo E; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research (DZIF), partner sites Hannover-Braunschweig and Hamburg-Lübeck-Borstel-Riems, Braunschweig, Germany.
Koch S; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research (DZIF), partner sites Hannover-Braunschweig and Hamburg-Lübeck-Borstel-Riems, Braunschweig, Germany.
Curth U; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.
Alkharsah KR; Department of Microbiology, College of Medicine, Imam Abdulrahman Bin Faisal University (IAU), Dammam, Saudi Arabia.
Ströh LJ; Institute of Virology, Hannover Medical School, Hannover, Germany.
Binz A; Institute of Virology, Hannover Medical School, Hannover, Germany.; Excellence Cluster 2155 RESIST, Hannover Medical School, Hannover, Germany.
Beneke JM; Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Luebeck, Luebeck, Germany.
Vollmer B; Centre for Structural Systems Biology, Leibniz-Institut für Experimentelle Virologie (HPI), Hamburg, Germany.
Böning H; Institute of Virology, Hannover Medical School, Hannover, Germany.
Borst EM; Institute of Virology, Hannover Medical School, Hannover, Germany.
Desai P; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University, Baltimore, Maryland, United States of America.
Bohne J; Institute of Virology, Hannover Medical School, Hannover, Germany.
Messerle M; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research (DZIF), partner sites Hannover-Braunschweig and Hamburg-Lübeck-Borstel-Riems, Braunschweig, Germany.; Excellence Cluster 2155 RESIST, Hannover Medical School, Hannover, Germany.
Bauerfeind R; Research Core Unit Laser Microscopy, Hannover Medical School, Hannover, Germany.
Legrand P; Synchrotron SOLEIL, L'Orme des Merisiers, Gif-sur-Yvette, France.
Sodeik B; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research (DZIF), partner sites Hannover-Braunschweig and Hamburg-Lübeck-Borstel-Riems, Braunschweig, Germany.; Excellence Cluster 2155 RESIST, Hannover Medical School, Hannover, Germany.
Schulz TF; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research (DZIF), partner sites Hannover-Braunschweig and Hamburg-Lübeck-Borstel-Riems, Braunschweig, Germany.; Excellence Cluster 2155 RESIST, Hannover Medical School, Hannover, Germany.
Krey T; Institute of Virology, Hannover Medical School, Hannover, Germany.; German Center for Infection Research (DZIF), partner sites Hannover-Braunschweig and Hamburg-Lübeck-Borstel-Riems, Braunschweig, Germany.; Excellence Cluster 2155 RESIST, Hannover Medical School, Hannover, Germany.; Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Luebeck, Luebeck, Germany.; Centre for Structural Systems Biology (CSSB), Hamburg, Germany.
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Źródło :
PLoS biology [PLoS Biol] 2021 Nov 04; Vol. 19 (11), pp. e3001423. Date of Electronic Publication: 2021 Nov 04 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Multimerization*
Herpesvirus 8, Human/*physiology
Open Reading Frames/*genetics
Viral Proteins/*metabolism
Virus Assembly/*physiology
Animals ; Capsid/chemistry ; Conserved Sequence ; Crystallography, X-Ray ; DNA Packaging ; DNA, Viral/genetics ; Drosophila ; HEK293 Cells ; Herpesvirus 8, Human/ultrastructure ; Humans ; Models, Molecular ; Mutagenesis/genetics ; Mutant Proteins/metabolism ; Viral Proteins/chemistry
Czasopismo naukowe
Tytuł :
Peptide Blocking Self-Polymerization of Extracellular Calcium-Sensing Receptor Attenuates Hypoxia-Induced Pulmonary Hypertension.
Autorzy :
Xiao R; From the Department of Pathophysiology, School of Basic Medicine (R.X., S.L., T.Z., L.Z., Q.H.).; Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.).
Luo S; From the Department of Pathophysiology, School of Basic Medicine (R.X., S.L., T.Z., L.Z., Q.H.).; Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.).
Zhang T; From the Department of Pathophysiology, School of Basic Medicine (R.X., S.L., T.Z., L.Z., Q.H.).; Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.).
Lv Y; Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.).; Department of Pathology (Y.L.), Tongji Hospital.
Wang T; Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.).; Department of Respiratory and Critical Care Medicine (T.W.), Tongji Hospital.
Zhang J; Department of Pathology (J.Z.).
Su Y; Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.).; Department of Respiratory and Critical Care Medicine, Union Hospital (Y.S.).
Ruiz M; Tongji Medical College, Huazhong University of Science and Technology (HUST), China; Department of Nutrition, Université de Montréal, Canada (M.R.).; Montreal Heart Institute, Canada (M.R., J.D.).
Dupuis J; Montreal Heart Institute, Canada (M.R., J.D.).; Department of medicine, Université de Montréal, Canada (J.D.).
Zhu L; From the Department of Pathophysiology, School of Basic Medicine (R.X., S.L., T.Z., L.Z., Q.H.).; Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.).
Hu Q; From the Department of Pathophysiology, School of Basic Medicine (R.X., S.L., T.Z., L.Z., Q.H.).; Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.).
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Źródło :
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2021 Nov; Vol. 78 (5), pp. 1605-1616. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Multimerization*
Hypertension, Pulmonary/*drug therapy
Hypoxia/*complications
Peptides/*pharmacology
Receptors, Calcium-Sensing/*antagonists & inhibitors
Animals ; Cells, Cultured ; Hypertension, Pulmonary/etiology ; Hypertension, Pulmonary/metabolism ; Male ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Receptors, Calcium-Sensing/chemistry ; Vasoconstriction/drug effects
Czasopismo naukowe
Tytuł :
Basolateral protein Scribble binds phosphatase PP1 to establish a signaling network maintaining apicobasal polarity.
Autorzy :
Troyanovsky RB; Department of Dermatology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Indra I; Department of Dermatology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Kato R; Department of Dermatology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Mitchell BJ; Department of Cell & Developmental Biology, The Feinberg School of Medicine, Chicago, Illinois, USA.
Troyanovsky SM; Department of Dermatology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; Department of Cell & Developmental Biology, The Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Nov; Vol. 297 (5), pp. 101289. Date of Electronic Publication: 2021 Oct 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cell Polarity*
Protein Multimerization*
Signal Transduction*
Epithelial Cells/*metabolism
Membrane Proteins/*metabolism
Receptors, Neuropeptide Y/*metabolism
Tumor Suppressor Proteins/*metabolism
Cell Line ; Humans ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Protein Binding ; Protein Domains ; Receptors, Neuropeptide Y/chemistry ; Receptors, Neuropeptide Y/genetics ; Tumor Suppressor Proteins/chemistry ; Tumor Suppressor Proteins/genetics
Czasopismo naukowe

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