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Title:
Evaluating antibiotic regimens for streptococcal toxic shock syndrome in children.
Authors:
Zhang H; Department of Pharmacy, Hunan Children's Hospital, Changsha, China.
Dong J; Pediatrics Research Institute of Hunan Province, Hunan Children's Hospital, Changsha, China.
Huang J; Department of Intensive Care Medicine, Hunan Children's Hospital, Changsha, China.
Zhang K; School of Medicine, Hunan Normal University, Changsha, China.
Lu X; Department of Intensive Care Medicine, Hunan Children's Hospital, Changsha, China.
Zhao X; Department of Pharmacy, Hunan Children's Hospital, Changsha, China.
Xiao C; Department of Pharmacy, Chenzhou First People's Hospital, Chenzhou, China.
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Source:
PloS one [PLoS One] 2023 Oct 12; Vol. 18 (10), pp. e0292311. Date of Electronic Publication: 2023 Oct 12 (Print Publication: 2023).
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Shock, Septic*/drug therapy
Streptococcal Infections*/drug therapy
Humans ; Child ; Anti-Bacterial Agents/therapeutic use ; Clindamycin/therapeutic use ; Retrospective Studies ; Streptococcus pyogenes ; Penicillins/therapeutic use ; Ampicillin/therapeutic use ; Protein Synthesis Inhibitors/therapeutic use ; Macrolides/therapeutic use
Academic Journal
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Title:
Influence of reconsolidation in maintenance of cocaine-associated contextual memories formed during adolescence or adulthood.
Authors:
Charpentier ANH; Department of Psychology, Behavioral Neuroscience, Michigan State University (MSU), Interdisciplinary Science and Technology Building, West Rm. 4010, 766 Service Rd., East Lansing, MI, 48824, USA.
Olekanma DI; Department of Psychology, Behavioral Neuroscience, Michigan State University (MSU), Interdisciplinary Science and Technology Building, West Rm. 4010, 766 Service Rd., East Lansing, MI, 48824, USA.
Valade CT; Department of Psychology, Behavioral Neuroscience, Michigan State University (MSU), Interdisciplinary Science and Technology Building, West Rm. 4010, 766 Service Rd., East Lansing, MI, 48824, USA.
Reeves CA; Department of Psychology, Behavioral Neuroscience, Michigan State University (MSU), Interdisciplinary Science and Technology Building, West Rm. 4010, 766 Service Rd., East Lansing, MI, 48824, USA.
Cho BR; Department of Psychology, Behavioral Neuroscience, Michigan State University (MSU), Interdisciplinary Science and Technology Building, West Rm. 4010, 766 Service Rd., East Lansing, MI, 48824, USA.
Arguello AA; Department of Psychology, Behavioral Neuroscience, Michigan State University (MSU), Interdisciplinary Science and Technology Building, West Rm. 4010, 766 Service Rd., East Lansing, MI, 48824, USA. .
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Scientific reports [Sci Rep] 2023 Aug 25; Vol. 13 (1), pp. 13936. Date of Electronic Publication: 2023 Aug 25.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Catheterization, Central Venous*
Cocaine*/pharmacology
Animals ; Rats ; Cycloheximide ; Protein Synthesis Inhibitors ; Administration, Cutaneous
Academic Journal
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Title:
Effect of veterinary feed directive rule changes on tetracycline-resistant and erythromycin-resistant bacteria (Salmonella, Escherichia, and Campylobacter) in retail meats in the United States.
Authors:
Sarkar S; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, United States of America.
Okafor C; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, United States of America.
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Source:
PloS one [PLoS One] 2023 Aug 03; Vol. 18 (8), pp. e0289208. Date of Electronic Publication: 2023 Aug 03 (Print Publication: 2023).
Publication Type:
Journal Article
MeSH Terms:
Campylobacter*
Animals ; Cattle ; United States ; Erythromycin/pharmacology ; Escherichia ; Drug Resistance, Bacterial ; Anti-Bacterial Agents/pharmacology ; Meat/microbiology ; Tetracycline/pharmacology ; Salmonella ; Chickens/microbiology ; Turkeys/microbiology ; Protein Synthesis Inhibitors/pharmacology ; Microbial Sensitivity Tests
Academic Journal
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Title:
Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis.
Authors:
Oudaert I; Department of Hematology and Immunology-Myeloma Center Brussels, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Brussels, Belgium.
Satilmis H; Department of Hematology and Immunology-Myeloma Center Brussels, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Brussels, Belgium.
Vlummens P; Department of Hematology and Immunology-Myeloma Center Brussels, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Brussels, Belgium.; Department of Clinical Hematology, Ghent University Hospital, Gent, Belgium.
De Brouwer W; Department of Hematology, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, 1090, Jette, Brussels, Belgium.
Maes A; Department of Hematology and Immunology-Myeloma Center Brussels, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Brussels, Belgium.
Hose D; Department of Hematology and Immunology-Myeloma Center Brussels, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Brussels, Belgium.
De Bruyne E; Department of Hematology and Immunology-Myeloma Center Brussels, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Brussels, Belgium.
Ghesquière B; Metabolomics Expertise Center, VIB Center for Cancer Biology (VIB-CCB) - Department of Oncology, KU Leuven, Leuven, Belgium.
Vanderkerken K; Department of Hematology and Immunology-Myeloma Center Brussels, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Brussels, Belgium.
De Veirman K; Department of Hematology and Immunology-Myeloma Center Brussels, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Brussels, Belgium.
Menu E; Department of Hematology and Immunology-Myeloma Center Brussels, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Brussels, Belgium. .
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Source:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2022 Feb 01; Vol. 41 (1), pp. 45. Date of Electronic Publication: 2022 Feb 01.
Publication Type:
Journal Article
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Bortezomib/*therapeutic use
Multiple Myeloma/*drug therapy
Protein Synthesis Inhibitors/*therapeutic use
Pyrroline Carboxylate Reductases/*therapeutic use
Animals ; Antineoplastic Agents/pharmacology ; Bortezomib/pharmacology ; Cell Proliferation ; Humans ; Mice ; Multiple Myeloma/mortality ; Multiple Myeloma/pathology ; Protein Synthesis Inhibitors/pharmacology ; Pyrroline Carboxylate Reductases/pharmacology ; Survival Analysis
Academic Journal
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Title:
Characterization of aminoglycoside resistance genes in multidrug-resistant Klebsiella pneumoniae collected from tertiary hospitals during the COVID-19 pandemic.
Authors:
Ahmed OB; Department of Environmental and Health Research, The Custodian of the Two Holy Mosques Institute for Hajj and Umrah Research, Umm Al-Qura University, Makkah, Saudi Arabia.
Asghar AH; Department of Environmental and Health Research, The Custodian of the Two Holy Mosques Institute for Hajj and Umrah Research, Umm Al-Qura University, Makkah, Saudi Arabia.
Bamaga M; Department of Environmental and Health Research, The Custodian of the Two Holy Mosques Institute for Hajj and Umrah Research, Umm Al-Qura University, Makkah, Saudi Arabia.
Bahwerth FS; King Faisal Hospital, Ministry of Health, Makkah, Saudi Arabia.
Ibrahim ME; Department of Basic Medical Sciences (Microbiology Unit), College of Medicine, University of Bisha, Bisha, Saudi Arabia.
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PloS one [PLoS One] 2023 Jul 28; Vol. 18 (7), pp. e0289359. Date of Electronic Publication: 2023 Jul 28 (Print Publication: 2023).
Publication Type:
Journal Article
MeSH Terms:
COVID-19*/epidemiology
Bacterial Infections*/epidemiology
Klebsiella Infections*/drug therapy
Klebsiella Infections*/epidemiology
Klebsiella Infections*/microbiology
Humans ; Aminoglycosides/pharmacology ; Aminoglycosides/therapeutic use ; Klebsiella pneumoniae ; Pandemics ; Tertiary Care Centers ; Drug Resistance, Bacterial/genetics ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Protein Synthesis Inhibitors/pharmacology ; Microbial Sensitivity Tests ; beta-Lactamases/genetics
Academic Journal
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Title:
GSI Treatment Preserves Protein Synthesis in C2C12 Myotubes.
Authors:
Huot JR; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Thompson B; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
McMullen C; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
Marino JS; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
Arthur ST; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
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Source:
Cells [Cells] 2021 Jul 15; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 15.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amyloid Precursor Protein Secretases/*drug effects
Muscle Fibers, Skeletal/*drug effects
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*pharmacology
Amyloid Precursor Protein Secretases/metabolism ; Animals ; Cell Differentiation/drug effects ; Mice ; Muscle Fibers, Skeletal/metabolism ; Muscle Proteins/metabolism ; Muscle, Skeletal/metabolism ; Myoblasts/drug effects ; Myoblasts/metabolism ; Protein Synthesis Inhibitors/metabolism ; Signal Transduction/drug effects
Academic Journal
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Title:
Kirkiin: A New Toxic Type 2 Ribosome-Inactivating Protein from the Caudex of Adenia kirkii .
Authors:
Bortolotti M; Department of Experimental, Diagnostic and Specialty Medicine-DIMES, General Pathology Section, Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.
Maiello S; Department of Experimental, Diagnostic and Specialty Medicine-DIMES, General Pathology Section, Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.
Ferreras JM; Department of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E-47011 Valladolid, Spain.
Iglesias R; Department of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E-47011 Valladolid, Spain.
Polito L; Department of Experimental, Diagnostic and Specialty Medicine-DIMES, General Pathology Section, Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.
Bolognesi A; Department of Experimental, Diagnostic and Specialty Medicine-DIMES, General Pathology Section, Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.
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Source:
Toxins [Toxins (Basel)] 2021 Jan 22; Vol. 13 (2). Date of Electronic Publication: 2021 Jan 22.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents, Phytogenic/*pharmacology
Neuroblastoma/*drug therapy
Passifloraceae/*enzymology
Protein Synthesis Inhibitors/*pharmacology
Ribosome Inactivating Proteins, Type 2/*pharmacology
Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/toxicity ; Cell Line, Tumor ; Cell Survival/drug effects ; Erythrocyte Aggregation/drug effects ; Humans ; Molecular Weight ; Neuroblastoma/metabolism ; Neuroblastoma/pathology ; Protein Biosynthesis/drug effects ; Protein Synthesis Inhibitors/isolation & purification ; Protein Synthesis Inhibitors/toxicity ; Ribosome Inactivating Proteins, Type 2/isolation & purification ; Ribosome Inactivating Proteins, Type 2/toxicity ; Ribosomes/drug effects ; Ribosomes/genetics ; Ribosomes/metabolism
Academic Journal
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Title:
The efficacy and safety of a homoharringtonine-based protocol for children with acute myeloid leukemia: A retrospective study in China.
Authors:
Tang Y; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
Luo C; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
Shen S; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
Xue H; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
Pan C; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
Hu W; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
Chen X; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
Cai J; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
Chen J; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
Tang J; Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Key Lab of Pediatric Hematology & Oncology of China Ministry of Health, Shanghai, China.
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Source:
Pediatric hematology and oncology [Pediatr Hematol Oncol] 2021 Mar; Vol. 38 (2), pp. 97-107. Date of Electronic Publication: 2020 Oct 05.
Publication Type:
Journal Article
MeSH Terms:
Homoharringtonine/*therapeutic use
Leukemia, Myeloid, Acute/*drug therapy
Protein Synthesis Inhibitors/*therapeutic use
Adolescent ; Child ; Child, Preschool ; China ; Female ; Homoharringtonine/pharmacology ; Humans ; Infant ; Infant, Newborn ; Male ; Protein Synthesis Inhibitors/pharmacology ; Retrospective Studies
Academic Journal
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Title:
A Quick Guide to Small-Molecule Inhibitors of Eukaryotic Protein Synthesis.
Authors:
Dmitriev SE; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia. .; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119234, Russia.; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Vladimirov DO; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119234, Russia.
Lashkevich KA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
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Source:
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2020 Nov; Vol. 85 (11), pp. 1389-1421.
Publication Type:
Journal Article; Review
MeSH Terms:
Anti-Bacterial Agents*/chemistry
Anti-Bacterial Agents*/therapeutic use
Protein Synthesis Inhibitors*/chemistry
Protein Synthesis Inhibitors*/therapeutic use
Eukaryotic Cells/*metabolism
Protein Biosynthesis/*drug effects
Humans
Academic Journal
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Title:
Antiviral Activity of Ribosome-Inactivating Proteins.
Authors:
Citores L; Department of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E-47011 Valladolid, Spain.
Iglesias R; Department of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E-47011 Valladolid, Spain.
Ferreras JM; Department of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, E-47011 Valladolid, Spain.
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Source:
Toxins [Toxins (Basel)] 2021 Jan 22; Vol. 13 (2). Date of Electronic Publication: 2021 Jan 22.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Pest Control, Biological*
Antiviral Agents/*pharmacology
Plant Diseases/*prevention & control
Plants, Genetically Modified/*enzymology
Protein Synthesis Inhibitors/*pharmacology
Ribosome Inactivating Proteins/*pharmacology
Toxins, Biological/*pharmacology
Virus Diseases/*drug therapy
Viruses/*drug effects
Animals ; Antiviral Agents/isolation & purification ; Humans ; Plant Diseases/genetics ; Plant Diseases/virology ; Plants, Genetically Modified/genetics ; Plants, Genetically Modified/virology ; Protein Synthesis Inhibitors/isolation & purification ; Ribosome Inactivating Proteins/isolation & purification ; Toxins, Biological/isolation & purification ; Virus Diseases/metabolism ; Virus Diseases/virology ; Viruses/metabolism ; Viruses/pathogenicity
Academic Journal
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Title:
Social Fear Memory Requires Two Stages of Protein Synthesis in Mice.
Authors:
Kornhuber J; Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Zoicas I; Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.; Department of Behavioural and Molecular Neurobiology, University of Regensburg, 93040 Regensburg, Germany.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 02; Vol. 21 (15). Date of Electronic Publication: 2020 Aug 02.
Publication Type:
Journal Article
MeSH Terms:
Anisomycin/*pharmacology
Fear/*drug effects
Memory/*drug effects
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*pharmacology
Animals ; Anisomycin/administration & dosage ; Conditioning, Classical/drug effects ; Male ; Mice ; Protein Synthesis Inhibitors/administration & dosage ; Time Factors
Academic Journal
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Title:
Exploring Drug Treatment Patterns Based on the Action of Drug and Multilayer Network Model.
Authors:
Yu L; School of Computer Science and Technology, Xidian University, Xi'an 710071, China.
Shi Y; School of Computer Science and Technology, Xidian University, Xi'an 710071, China.
Zou Q; Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology, Chengdu 650004, China.
Wang S; Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.
Zheng L; School of Computer Science and Technology, Liaocheng University, Liaocheng 252000, China.
Gao L; School of Computer Science and Technology, Xidian University, Xi'an 710071, China.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2020 Jul 16; Vol. 21 (14). Date of Electronic Publication: 2020 Jul 16.
Publication Type:
Journal Article
MeSH Terms:
Gene Regulatory Networks/*drug effects
Hydroxamic Acids/*pharmacology
Protein Interaction Maps/*drug effects
Protein Synthesis Inhibitors/*pharmacology
Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Drug Repositioning ; Female ; Gene Ontology ; Humans ; Hydroxamic Acids/therapeutic use ; Leukemia/drug therapy ; Leukemia/genetics ; Leukemia/metabolism ; Male ; Models, Biological ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/metabolism ; Protein Synthesis Inhibitors/therapeutic use ; Transcriptome/drug effects
Academic Journal
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Title:
Preprotein signature for full susceptibility to the co-translational translocation inhibitor cyclotriazadisulfonamide.
Authors:
Van Puyenbroeck V; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Pauwels E; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Provinciael B; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Bell TW; Department of Chemistry, University of Nevada, Reno, Nevada.
Schols D; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Kalies KU; Centre for Structural and Cell Biology in Medicine, Institute of Biology, University of Lübeck, Lübeck, Germany.
Hartmann E; Centre for Structural and Cell Biology in Medicine, Institute of Biology, University of Lübeck, Lübeck, Germany.
Vermeire K; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
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Source:
Traffic (Copenhagen, Denmark) [Traffic] 2020 Feb; Vol. 21 (2), pp. 250-264. Date of Electronic Publication: 2019 Nov 25.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4 Antigens*/metabolism
Protein Sorting Signals*/drug effects
Protein Synthesis Inhibitors*/pharmacology
Endoplasmic Reticulum/metabolism ; Humans ; Hydrophobic and Hydrophilic Interactions ; Protein Processing, Post-Translational/drug effects
Academic Journal
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Title:
Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline.
Authors:
Jagdmann J; Uppsala University, Department of Medical Biochemistry and Microbiology, Uppsala, Sweden.
Andersson DI; Uppsala University, Department of Medical Biochemistry and Microbiology, Uppsala, Sweden.
Nicoloff H; Uppsala University, Department of Medical Biochemistry and Microbiology, Uppsala, Sweden.
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Source:
PLoS biology [PLoS Biol] 2022 Sep 28; Vol. 20 (9), pp. e3001808. Date of Electronic Publication: 2022 Sep 28 (Print Publication: 2022).
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Escherichia coli*/genetics
Tetracyclines*/pharmacology
Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Microbial Sensitivity Tests ; Mutation/genetics ; Plasmids ; Protein Synthesis Inhibitors/pharmacology ; Tigecycline/pharmacology
Academic Journal
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Title:
Conjugates of Desmycosin with Fragments of Antimicrobial Peptide Oncocin: Synthesis, Antibacterial Activity, Interaction with Ribosome.
Authors:
Khairullina ZZ; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.
Makarov GI; South Ural State University, Chelyabinsk, 454080, Russia.
Tereshchenkov AG; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119992, Russia.
Buev VS; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119992, Russia.
Lukianov DA; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.; Skolkovo Institute of Science and Technology, Skolkovo, 143025, Russia.
Polshakov VI; Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow, 119991, Russia.
Tashlitsky VN; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.
Osterman IA; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.; Skolkovo Institute of Science and Technology, Skolkovo, 143025, Russia.
Sumbatyan NV; Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia. .
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Source:
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2022 Sep; Vol. 87 (9), pp. 871-889.
Publication Type:
Journal Article
MeSH Terms:
Antimicrobial Peptides*
Escherichia coli*/metabolism
Anti-Bacterial Agents/chemistry ; Antimicrobial Cationic Peptides/pharmacology ; Bacterial Proteins/metabolism ; Macrolides/analysis ; Macrolides/metabolism ; Protein Synthesis Inhibitors/chemistry ; RNA/metabolism ; Ribosomes/chemistry ; Tylosin/analogs & derivatives
Academic Journal
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Title:
Ribotoxic Proteins, Known as Inhibitors of Protein Synthesis, from Mushrooms and Other Fungi According to Endo's Fragment Detection.
Authors:
Landi N; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.
Hussain HZF; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.
Pedone PV; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.
Ragucci S; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.
Di Maro A; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.
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Source:
Toxins [Toxins (Basel)] 2022 Jun 13; Vol. 14 (6). Date of Electronic Publication: 2022 Jun 13.
Publication Type:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Agaricales*/metabolism
Ricin*/metabolism
Adenine/metabolism ; Aniline Compounds ; Animals ; Plant Proteins/metabolism ; Protein Synthesis Inhibitors/pharmacology ; RNA, Ribosomal/analysis ; RNA, Ribosomal/metabolism ; Rats ; Ribosome Inactivating Proteins/metabolism ; Ribosomes/metabolism
Academic Journal
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Title:
The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.
Authors:
Friesen WJ; PTC Therapeutics, South Plainfield, NJ, United States of America.
Johnson B; PTC Therapeutics, South Plainfield, NJ, United States of America.
Sierra J; PTC Therapeutics, South Plainfield, NJ, United States of America.
Zhuo J; PTC Therapeutics, South Plainfield, NJ, United States of America.
Vazirani P; PTC Therapeutics, South Plainfield, NJ, United States of America.
Xue X; PTC Therapeutics, South Plainfield, NJ, United States of America.
Tomizawa Y; PTC Therapeutics, South Plainfield, NJ, United States of America.
Baiazitov R; PTC Therapeutics, South Plainfield, NJ, United States of America.
Morrill C; PTC Therapeutics, South Plainfield, NJ, United States of America.
Ren H; PTC Therapeutics, South Plainfield, NJ, United States of America.
Babu S; PTC Therapeutics, South Plainfield, NJ, United States of America.
Moon YC; PTC Therapeutics, South Plainfield, NJ, United States of America.
Branstrom A; PTC Therapeutics, South Plainfield, NJ, United States of America.
Mollin A; PTC Therapeutics, South Plainfield, NJ, United States of America.
Hedrick J; PTC Therapeutics, South Plainfield, NJ, United States of America.
Sheedy J; PTC Therapeutics, South Plainfield, NJ, United States of America.
Elfring G; PTC Therapeutics, South Plainfield, NJ, United States of America.
Weetall M; PTC Therapeutics, South Plainfield, NJ, United States of America.
Colacino JM; PTC Therapeutics, South Plainfield, NJ, United States of America.
Welch EM; PTC Therapeutics, South Plainfield, NJ, United States of America.
Peltz SW; PTC Therapeutics, South Plainfield, NJ, United States of America.
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Source:
PloS one [PLoS One] 2018 Oct 25; Vol. 13 (10), pp. e0206158. Date of Electronic Publication: 2018 Oct 25 (Print Publication: 2018).
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Codon, Nonsense/*chemical synthesis
Genetic Diseases, Inborn/*drug therapy
Gentamicins/*pharmacology
Protein Synthesis Inhibitors/*pharmacology
Aminoglycosides/pharmacology ; Aminoglycosides/therapeutic use ; Animals ; Antibiotics, Antineoplastic/pharmacology ; Cells, Cultured ; Codon, Terminator/chemical synthesis ; Embryo, Nonmammalian ; Gentamicins/chemistry ; Gentamicins/therapeutic use ; Humans ; Kidney Diseases/chemically induced ; Kidney Diseases/pathology ; Male ; Open Reading Frames/drug effects ; Open Reading Frames/genetics ; Protein Synthesis Inhibitors/therapeutic use ; Rats ; Rats, Sprague-Dawley ; Zebrafish/embryology
Academic Journal
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Title:
Helicobacter pylori resistance to antibiotics before and after treatment: Incidence of eradication failure.
Authors:
Nestegard O; Ringerike Hospital, Vestre Viken Health trust, Hønefoss, Norway.; Research Group Gastroenterology and Nutrition, Department of Clinical Medicine, UiT the Artic University, Tromsø, Norway.
Moayeri B; Department of Microbiology, Oslo University Hospital, Oslo, Norway.
Halvorsen FA; Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway.
Tønnesen T; Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway.
Sørbye SW; Department of Pathology, University Hospital of North Norway, Tromsø, Norway.
Paulssen E; Research Group Gastroenterology and Nutrition, Department of Clinical Medicine, UiT the Artic University, Tromsø, Norway.
Johnsen KM; Research Group Gastroenterology and Nutrition, Department of Clinical Medicine, UiT the Artic University, Tromsø, Norway.
Goll R; Research Group Gastroenterology and Nutrition, Department of Clinical Medicine, UiT the Artic University, Tromsø, Norway.
Florholmen JR; Research Group Gastroenterology and Nutrition, Department of Clinical Medicine, UiT the Artic University, Tromsø, Norway.
Melby KK; Department of Microbiology, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
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Source:
PloS one [PLoS One] 2022 Apr 20; Vol. 17 (4), pp. e0265322. Date of Electronic Publication: 2022 Apr 20 (Print Publication: 2022).
Publication Type:
Clinical Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Helicobacter Infections*/diagnosis
Helicobacter Infections*/drug therapy
Helicobacter Infections*/epidemiology
Helicobacter pylori*
Amoxicillin/pharmacology ; Amoxicillin/therapeutic use ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Clarithromycin/pharmacology ; Clarithromycin/therapeutic use ; Drug Resistance, Bacterial ; Humans ; Incidence ; Levofloxacin/therapeutic use ; Metronidazole/pharmacology ; Metronidazole/therapeutic use ; Microbial Sensitivity Tests ; Omeprazole ; Protein Synthesis Inhibitors ; Tetracycline
Academic Journal
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Title:
Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1.
Authors:
Peukert K; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Steinhagen F; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.; Department of Anesthesiology and Intensive Care Medicine, SHG Hospital Voelklingen, Richard-Str. 5-9, 66333, Voelklingen, Germany.
Fox M; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Feuerborn C; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Schulz S; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Seeliger B; Department of Respiratory Medicine and German Centre of Lung Research (DZL), Hannover Medical School, Carl-Neuberg-Str. 1, 30635, Hannover, Germany.
Schuss P; Department of Neurosurgery, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Schneider M; Department of Neurosurgery, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Frede S; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Sauer A; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Putensen C; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Latz E; Institute of Innate Immunity, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Wilhelm C; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Bode C; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany. .
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Source:
Respiratory research [Respir Res] 2022 Feb 07; Vol. 23 (1), pp. 21. Date of Electronic Publication: 2022 Feb 07.
Publication Type:
Journal Article
MeSH Terms:
Caspase 1/*metabolism
Caspase Inhibitors/*therapeutic use
Pneumonia/*drug therapy
Pulmonary Fibrosis/*drug therapy
Tetracycline/*therapeutic use
Animals ; Disease Models, Animal ; Male ; Mice ; Mice, Inbred C57BL ; Pneumonia/chemically induced ; Pneumonia/metabolism ; Protein Synthesis Inhibitors/therapeutic use ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/metabolism ; Silicon Dioxide/toxicity
Academic Journal
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Title:
Evolutionary paths to macrolide resistance in a Neisseria commensal converge on ribosomal genes through short sequence duplications.
Authors:
Raisman JC; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Fiore MA; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Tomin L; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Adjei JKO; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Aswad VX; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Chu J; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Domondon CJ; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Donahue BA; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Masciotti CA; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
McGrath CG; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Melita J; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Podbielski PA; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Schreiner MR; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Trumpore LJ; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Wengert PC; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Wrightstone EA; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Hudson AO; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
Wadsworth CB; Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, NY, United States of America.
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Source:
PloS one [PLoS One] 2022 Jan 13; Vol. 17 (1), pp. e0262370. Date of Electronic Publication: 2022 Jan 13 (Print Publication: 2022).
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Resistance, Bacterial/*genetics
Macrolides/*pharmacology
Neisseria/*genetics
Anti-Bacterial Agents/pharmacology ; Azithromycin/pharmacology ; Microbial Sensitivity Tests ; Microbiota/genetics ; Protein Synthesis Inhibitors ; RNA, Ribosomal, 23S/genetics ; Ribosomal Proteins/genetics ; Ribosome Subunits, Large, Bacterial/genetics ; Ribosome Subunits, Small, Bacterial/genetics ; Ribosomes/genetics ; Sequence Deletion/genetics
Academic Journal
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Showing 1-20 from 1296 results

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